Publications

Publications from OUS - Cellular membrane dynamics (Stenmark)

776 publications found

Publications 2025

Bäcker N, Ast J, Martorana D, Renicke C, Berger J, Mais CN, Christ M, Stehlik T, Heimerl T, Wernet V, Taxis C, Pané-Farré J, Bölker M, Klatt JM, Sandrock B, Schink KO, Bange G, Freitag J (2025)
Peroxisomal core structures segregate diverse metabolic pathways
Nat Commun, 16 (1), 1802
DOI 10.1038/s41467-025-57053-9, PubMed 39979331
Droste M, Puhka M, van Royen ME, Ng MSY, Blijdorp C, Alvarez-Llamas G, Borràs FE, Büscher AK, Bussolati B, Dear JW, Falcón-Pérez JM, Giebel B, Grange C, Hoorn EJ, Leivo J, Lenassi M, Llorente A, Lucien F, Mertens I, Mischak H, Pink D, Tertel T, Tiwari S, Di Vizio D, Yuen PST et al. (2025)
Roadblocks of Urinary EV Biomarkers: Moving Toward the Clinic
J Extracell Vesicles, 14 (7), e70120
DOI 10.1002/jev2.70120, PubMed 40673839
Haukaas HS, Stenmark H (2025)
Phosphoinositides as regulators of membrane contact sites
Biochim Biophys Acta Mol Cell Biol Lipids, 1870 (7), 159673
DOI 10.1016/j.bbalip.2025.159673, PubMed 40721165
Hurley JH, Coyne AN, Miączyńska M, Stenmark H (2025)
The expanding repertoire of ESCRT functions in cell biology and disease
Nature, 642 (8069), 877-888
DOI 10.1038/s41586-025-08950-y, PubMed 40562928
Jayakumar N, Villegas-Hernández LE, Zhao W, Mao H, Dullo FT, Tinguely JC, Sagini K, Llorente A, Ahluwalia BS (2025)
Chip-based label-free incoherent super-resolution optical microscopy
Light Sci Appl, 14 (1), 259
DOI 10.1038/s41377-025-01914-x, PubMed 40754581
Kaur N, Carlsson SR, Lystad AH (2025)
Lysosome-associated CASM: from upstream triggers to downstream effector mechanisms
Front Cell Dev Biol, 13, 1559125
DOI 10.3389/fcell.2025.1559125, PubMed 40213394
Kondo T, Bourassa FXP, Achar S, DuSold J, Céspedes PF, Ando M, Dwivedi A, Moraly J, Chien C, Majdoul S, Kenet AL, Wahlsten M, Kvalvaag A, Jenkins E, Kim SP, Ade CM, Yu Z, Gaud G, Davila M, Love P, Yang JC, Dustin ML, Altan-Bonnet G, François P, Taylor N (2025)
Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity
Cell, 188 (9), 2372-2389.e35
DOI 10.1016/j.cell.2025.03.017, PubMed 40220754
Lystad AH (2025)
V-ATPase assembly at leaky lysosomes
Nat Struct Mol Biol, 32 (10), 1862-1864
DOI 10.1038/s41594-025-01612-7, PubMed 40646311
Medhus A, Schink KO, Longva AS, Engebraaten O, Berg K, Weyergang A (2025)
The mechanisms of HER2 targeted ADCs are dependent on Rab GTPases
Ther Adv Med Oncol, 17, 17588359251332473
DOI 10.1177/17588359251332473, PubMed 40297622
Mlynska A, Dobrovolskiene N, Suveizde K, Lukaseviciute G, Sagini K, Martin-Gracia B, Romero S, Llorente A, Line A, Butkute A, Gudaite B, Venckunas T, Matuseviciene N, Pasukoniene V (2025)
Exercise-induced extracellular vesicles delay tumor development by igniting inflammation in an immunologically cold triple-negative breast cancer mouse model
J Sport Health Sci, 14, 101041 (in press)
DOI 10.1016/j.jshs.2025.101041, PubMed 40250619
Nita A, Abraham SP, Elrefaay ER, Fafilek B, Cizkova E, Ursachi VC, Gudernova I, Koudelka A, Dudeja P, Gregor T, Feketova Z, Rico G, Svozilova K, Celiker C, Czyrek AA, Barta T, Trantirek L, Wiedlocha A, Krejci P, Bosakova M (2025)
FGFR2 residence in primary cilia is necessary for epithelial cell signaling
J Cell Biol, 224 (7)
DOI 10.1083/jcb.202311030, PubMed 40257378
Puurand M, Llorente A, Linē A, Kaambre T (2025)
Exercise-induced extracellular vesicles in reprogramming energy metabolism in cancer
Front Oncol, 14, 1480074
DOI 10.3389/fonc.2024.1480074, PubMed 39834935
Radulovic M, Yang C, Stenmark H (2025)
Lysosomal membrane homeostasis and its importance in physiology and disease
Nat Rev Mol Cell Biol (in press)
DOI 10.1038/s41580-025-00873-w, PubMed 40759742
Sagini K, Selvarajah M, Romero S, Bassols-Citores E, Martin-Gracia B, Ramirez-Garrastacho M, Rise F, Endzeliņš E, Sadovska L, Skorinkina D, Boguševiča M, Cešeiko R, Čampa M, Klavina A, Linē A, Llorente A (2025)
The Redox Enzyme Thioredoxin Is Increased in Plasma Extracellular Vesicles From Endurance-Trained Females in Response to Acute Exercise
FASEB J, 39 (16), e70927
DOI 10.1096/fj.202500678R, PubMed 40810354
Skotland T, Ekroos K, Llorente A, Sandvig K (2025)
Quantitative Lipid Analysis of Extracellular Vesicle Preparations: A Perspective
J Extracell Vesicles, 14 (3), e70049
DOI 10.1002/jev2.70049, PubMed 40091364
Trachsel-Moncho L, Veroni C, Mathai BJ, Lapao A, Singh S, Asp NT, Schultz SW, Pankiv S, Simonsen A (2025)
SNX10 functions as a modulator of piecemeal mitophagy and mitochondrial bioenergetics
J Cell Biol, 224 (5)
DOI 10.1083/jcb.202404009, PubMed 40052924
Tunset ME, Haslene-Hox H, Larsen JB, Kondziella D, Nygård M, Pedersen SA, Vaaler A, Llorente A (2025)
Clinical studies of blood-borne Extracellular vesicles in psychiatry: A systematic review
J Psychiatr Res, 182, 373-390
DOI 10.1016/j.jpsychires.2025.01.037, PubMed 39862765
Valsala Kumari R, Pandya AD, Pettersen SJ, Kvalvaag A, Myrann AG, Ghiarasim R, Rotaru A, Dimofte MG, Skotland T, Sandvig K, Mari Mælandsmo G, Iversen TG (2025)
Evaluation of HER2 Targeted Poly(Ethylene Glycol)-Poly(L-histidine) Copolymer Micelles in Breast Cancer Models
Macromol Biosci, e00047 (in press)
DOI 10.1002/mabi.202500047, PubMed 40719176
Valsalakumari R, Feith M, Pettersen S, Åslund AKO, Mørch Ý, Skotland T, Sandvig K, Mælandsmo GM, Iversen TG (2025)
Combinatorial Effects of Free and Nanoencapsulated Forms of Cabazitaxel and RAS-Selective Lethal 3 in Breast Cancer Cells
Pharmaceutics, 17 (5)
DOI 10.3390/pharmaceutics17050657, PubMed 40430947
Zhen Y, Stenmark H (2025)
Sustained release of cytokines from migrasomes
Extracell Vesicles Circ Nucl Acids, 6 (1), 171-175
DOI 10.20517/evcna.2025.15, PubMed 40206805

Publications 2024

Brugger M, Lauri A, Zhen Y, Gramegna LL, Zott B, Sekulić N, Fasano G, Kopajtich R, Cordeddu V, Radio FC, Mancini C, Pizzi S, Paradisi G, Zanni G, Vasco G, Carrozzo R, Palombo F, Tonon C, Lodi R, La Morgia C, Arelin M, Blechschmidt C, Finck T, Sørensen V, Kreiser K et al. (2024)
Bi-allelic variants in SNF8 cause a disease spectrum ranging from severe developmental and epileptic encephalopathy to syndromic optic atrophy
Am J Hum Genet, 111 (3), 594-613
DOI 10.1016/j.ajhg.2024.02.005, PubMed 38423010
Duran J, Salinas JE, Wheaton RP, Poolsup S, Allers L, Rosas-Lemus M, Chen L, Cheng Q, Pu J, Salemi M, Phinney B, Ivanov P, Lystad AH, Bhaskar K, Rajaiya J, Perkins DJ, Jia J (2024)
Calcium signaling from damaged lysosomes induces cytoprotective stress granules
EMBO J, 43 (24), 6410-6443
DOI 10.1038/s44318-024-00292-1, PubMed 39533058
Hamid MHBA, Cespedes PF, Jin C, Chen JL, Gileadi U, Antoun E, Liang Z, Gao F, Teague R, Manoharan N, Maldonado-Perez D, Khalid-Alham N, Cerundolo L, Ciaoca R, Hester SS, Pinto-Fernández A, Draganov SD, Vendrell I, Liu G, Yao X, Kvalvaag A, Dominey-Foy DCC, Nanayakkara C, Kanellakis N, Chen YL et al. (2024)
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity
Nat Immunol, 25 (5), 834-846
DOI 10.1038/s41590-024-01802-3, PubMed 38561495
Klavina A, Ceseiko R, Campa M, Jermolenko GF, Eglitis K, Llorente A, Linē A (2024)
The Effect of High-Intensity Interval Training on Quality of Life and Incidence of Chemotherapy Side Effects in Women With Breast Cancer
Integr Cancer Ther, 23, 15347354241297385
DOI 10.1177/15347354241297385, PubMed 39548802
Kvalvaag A, Dustin ML (2024)
Clathrin controls bidirectional communication between T cells and antigen presenting cells
Bioessays, 46 (4), e2300230
DOI 10.1002/bies.202300230, PubMed 38412391
Lamsal A, Andersen SB, Johansson I, Desgarnier MD, Wolowczyk C, Engedal N, Vietri M, Bjørkøy G, Giambelluca MS, Pettersen K (2024)
Elucidating the power of arginine restriction: taming type I interferon response in breast cancer via selective autophagy
Cell Commun Signal, 22 (1), 481
DOI 10.1186/s12964-024-01858-6, PubMed 39380098
Llorente A, Brokāne A, Mlynska A, Puurand M, Sagini K, Folkmane S, Hjorth M, Martin-Gracia B, Romero S, Skorinkina D, Čampa M, Cešeiko R, Romanchikova N, Kļaviņa A, Käämbre T, Linē A (2024)
From sweat to hope: The role of exercise-induced extracellular vesicles in cancer prevention and treatment
J Extracell Vesicles, 13 (8), e12500
DOI 10.1002/jev2.12500, PubMed 39183543
Nähse V, Stenmark H, Schink KO (2024)
Omegasomes control formation, expansion, and closure of autophagosomes
Bioessays, 46 (6), e2400038
DOI 10.1002/bies.202400038, PubMed 38724256
Pankiv S, Dahl AK, Aas A, Andersen RL, Brech A, Holland P, Singh S, Bindesbøll C, Simonsen A (2024)
BEACH domain proteins function as cargo-sorting adaptors in secretory and endocytic pathways
J Cell Biol, 223 (12)
DOI 10.1083/jcb.202408173, PubMed 39514288
Philips EA, Liu J, Kvalvaag A, Mørch AM, Tocheva AS, Ng C, Liang H, Ahearn IM, Pan R, Luo CC, Leithner A, Qin Z, Zhou Y, Garcia-España A, Mor A, Littman DR, Dustin ML, Wang J, Kong XP (2024)
Transmembrane domain-driven PD-1 dimers mediate T cell inhibition
Sci Immunol, 9 (93), eade6256
DOI 10.1126/sciimmunol.ade6256, PubMed 38457513
Radulovic M, Stenmark H (2024)
Lysophagy prevents neurotoxic aggregate transmission
Proc Natl Acad Sci U S A, 121 (3), e2321181121
DOI 10.1073/pnas.2321181121, PubMed 38190545
Sandvig K, Iversen TG, Skotland T (2024)
Entry of nanoparticles into cells and tissues: status and challenges
Beilstein J Nanotechnol, 15, 1017-1029
DOI 10.3762/bjnano.15.83, PubMed 39161463
Skotland T, Ekroos K, McDonald J, Ahrends R, Liebisch G, Sandvig K (2024)
Pitfalls in lipid mass spectrometry of mammalian samples - a brief guide for biologists
Nat Rev Mol Cell Biol, 25 (10), 759-760
DOI 10.1038/s41580-024-00758-4, PubMed 38951702
Totland MZ, Knudsen LM, Rasmussen NL, Omori Y, Sørensen V, Elster VCW, Stenersen JM, Larsen M, Jensen CL, Zickfeldt Lade AA, Bruusgaard E, Basing S, Kryeziu K, Brech A, Aasen T, Lothe RA, Leithe E (2024)
The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation
Cell Mol Life Sci, 81 (1), 171
DOI 10.1007/s00018-024-05165-8, PubMed 38597989
Valsalakumari R, Pandya AD, Prasmickaite L, Kvalvaag A, Myrann AG, Åslund AKO, Kjos MS, Fontecha-Cuenca C, Haroon HB, Ribeiro ARS, Horejs-Hoeck J, Moghimi SM, Mørch Ý, Skotland T, Sandvig K, Mælandsmo GM, Iversen TG (2024)
Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
Int J Nanomedicine, 19, 3009-3029
DOI 10.2147/IJN.S450283, PubMed 38562610
Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S et al. (2024)
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
J Extracell Vesicles, 13 (2), e12404
DOI 10.1002/jev2.12404, PubMed 38326288
Wenzel EM, Pedersen NM, Elfmark LA, Wang L, Kjos I, Stang E, Malerød L, Brech A, Stenmark H, Raiborg C (2024)
Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
Nat Commun, 15 (1), 1277
DOI 10.1038/s41467-024-45558-8, PubMed 38341434
Zhen Y, Stenmark H (2024)
A dual-purpose fusion complex in autophagy
Cell Res, 34 (3), 183-184
DOI 10.1038/s41422-023-00925-w, PubMed 38228880
Zhen Y, Stenmark H (2024)
Exosome regulation by Rubicon in ageing
Nat Cell Biol, 26 (9), 1380-1381
DOI 10.1038/s41556-024-01482-z, PubMed 39174741

Publications 2023

Bajo-Santos C, Brokāne A, Zayakin P, Endzeliņš E, Soboļevska K, Belovs A, Jansons J, Sperga M, Llorente A, Radoviča-Spalviņa I, Lietuvietis V, Linē A (2023)
Plasma and urinary extracellular vesicles as a source of RNA biomarkers for prostate cancer in liquid biopsies
Front Mol Biosci, 10, 980433
DOI 10.3389/fmolb.2023.980433, PubMed 36818049
Capera J, Jainarayanan A, Navarro-Pérez M, Valvo S, Demetriou P, Depoil D, Estadella I, Kvalvaag A, Felce JH, Felipe A, Dustin ML (2023)
Dynamics and spatial organization of Kv1.3 at the immunological synapse of human CD4+ T cells
Biophys J, 123 (15), 2271-2281
DOI 10.1016/j.bpj.2023.08.011, PubMed 37596785
Clement D, Szabo EK, Krokeide SZ, Wiiger MT, Vincenti M, Palacios D, Chang YT, Grimm C, Patel S, Stenmark H, Brech A, Majhi RK, Malmberg KJ (2023)
The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk
J Immunol, 211 (9), 1348-1358
DOI 10.4049/jimmunol.2300406, PubMed 37737664
Elfmark LA, Wenzel EM, Wang L, Pedersen NM, Stenmark H, Raiborg C (2023)
Protrudin-mediated ER-endosome contact sites promote phagocytosis
Cell Mol Life Sci, 80 (8), 216
DOI 10.1007/s00018-023-04862-0, PubMed 37468729
Hessvik NP, Sagini K, Romero S, Ramirez-Garrastacho M, Rodriguez M, Tutturen AEV, Kvalvaag A, Stang E, Brech A, Sandvig K, Llorente A (2023)
siRNA screening reveals that SNAP29 contributes to exosome release
Cell Mol Life Sci, 80 (7), 177
DOI 10.1007/s00018-023-04822-8, PubMed 37285022
Holme B, Bjørnerud B, Pedersen NM, de la Ballina LR, Wesche J, Haugsten EM (2023)
Automated tracking of cell migration in phase contrast images with CellTraxx
Sci Rep, 13 (1), 22982
DOI 10.1038/s41598-023-50227-9, PubMed 38151514
Kaur N, Carlsson SR, Lystad AH (2023)
The separate axes of TECPR1 and ATG16L1 in CASM
Autophagy, 20 (1), 214-215
DOI 10.1080/15548627.2023.2255462, PubMed 37676042
Kaur N, de la Ballina LR, Haukaas HS, Torgersen ML, Radulovic M, Munson MJ, Sabirsh A, Stenmark H, Simonsen A, Carlsson SR, Lystad AH (2023)
TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
EMBO J, 42 (17), e113105
DOI 10.15252/embj.2022113105, PubMed 37409525
Kvalvaag A, Valvo S, Céspedes PF, Saliba DG, Kurz E, Korobchevskaya K, Dustin ML (2023)
Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse
Proc Natl Acad Sci U S A, 120 (6), e2211368120
DOI 10.1073/pnas.2211368120, PubMed 36730202
Lampart A, Krowarsch D, Biadun M, Sorensen V, Szymczyk J, Sluzalska K, Wiedlocha A, Otlewski J, Zakrzewska M (2023)
Intracellular FGF1 protects cells from apoptosis through direct interaction with p53
Cell Mol Life Sci, 80 (10), 311
DOI 10.1007/s00018-023-04964-9, PubMed 37783936
Lamsal A, Andersen SB, Johansson I, Vietri M, Bokil AA, Kurganovs NJ, Rylander F, Bjørkøy G, Pettersen K, Giambelluca MS (2023)
Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer
Cell Commun Signal, 21 (1), 50
DOI 10.1186/s12964-023-01062-y, PubMed 36882786
Migliano SM, Schultz SW, Wenzel EM, Takáts S, Liu D, Mørk S, Tan KW, Rusten TE, Raiborg C, Stenmark H (2023)
Removal of hypersignaling endosomes by simaphagy
Autophagy, 20 (4), 769-791
DOI 10.1080/15548627.2023.2267958, PubMed 37840274
Nunzi E, Mezzasoma L, Bellezza I, Zelante T, Orvietani P, Coata G, Giardina I, Sagini K, Manni G, Di Michele A, Gargaro M, Talesa VN, Di Renzo GC, Fallarino F, Romani R (2023)
Microbiota-Associated HAF-EVs Regulate Monocytes by Triggering or Inhibiting Inflammasome Activation
Int J Mol Sci, 24 (3)
DOI 10.3390/ijms24032527, PubMed 36768851
Nähse V, Raiborg C, Tan KW, Mørk S, Torgersen ML, Wenzel EM, Nager M, Salo VT, Johansen T, Ikonen E, Schink KO, Stenmark H (2023)
ATPase activity of DFCP1 controls selective autophagy
Nat Commun, 14 (1), 4051
DOI 10.1038/s41467-023-39641-9, PubMed 37422481
Nähse V, Schink KO, Stenmark H (2023)
ATPase-regulated autophagosome biogenesis
Autophagy, 20 (1), 218-219
DOI 10.1080/15548627.2023.2255967, PubMed 37722386
Perdreau-Dahl H, Lipsett DB, Frisk M, Kermani F, Carlson CR, Brech A, Shen X, Bergan-Dahl A, Hou Y, Tuomainen T, Tavi P, Jones PP, Lunde M, Wasserstrom JA, Laporte J, Ullrich ND, Christensen G, Morth JP, Louch WE (2023)
BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes
Circ Res, 132 (11), e188-e205
DOI 10.1161/CIRCRESAHA.122.321732, PubMed 37139790
Pust S, Brech A, Wegner CS, Stenmark H, Haglund K (2023)
Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis
Cell Mol Life Sci, 80 (8), 235
DOI 10.1007/s00018-023-04864-y, PubMed 37523003
Sagini K, Urbanelli L, Buratta S, Emiliani C, Llorente A (2023)
Lipid Biomarkers in Liquid Biopsies: Novel Opportunities for Cancer Diagnosis
Pharmaceutics, 15 (2)
DOI 10.3390/pharmaceutics15020437, PubMed 36839759
Sandoz PA, Kuhnigk K, Szabo EK, Thunberg S, Erikson E, Sandström N, Verron Q, Brech A, Watzl C, Wagner AK, Alici E, Malmberg KJ, Uhlin M, Önfelt B (2023)
Modulation of lytic molecules restrain serial killing in γδ T lymphocytes
Nat Commun, 14 (1), 6035
DOI 10.1038/s41467-023-41634-7, PubMed 37758698
Sarmento MJ, Llorente A, Petan T, Khnykin D, Popa I, Nikolac Perkovic M, Konjevod M, Jaganjac M (2023)
The expanding organelle lipidomes: current knowledge and challenges
Cell Mol Life Sci, 80 (8), 237
DOI 10.1007/s00018-023-04889-3, PubMed 37530856
Skotland T, Llorente A, Sandvig K (2023)
Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?
Cold Spring Harb Perspect Biol, 15 (8)
DOI 10.1101/cshperspect.a041415, PubMed 37277192
Stonyte V, Mastrangelopoulou M, Timmer R, Lindbergsengen L, Vietri M, Campsteijn C, Grallert B (2023)
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity
EMBO Rep, 24 (8), e56100
DOI 10.15252/embr.202256100, PubMed 37291955
Totland MZ, Omori Y, Sørensen V, Kryeziu K, Aasen T, Brech A, Leithe E (2023)
Endocytic trafficking of connexins in cancer pathogenesis
Biochim Biophys Acta Mol Basis Dis, 1869 (7), 166812
DOI 10.1016/j.bbadis.2023.166812, PubMed 37454772
van den Berg CM, Volkov VA, Schnorrenberg S, Huang Z, Stecker KE, Grigoriev I, Gilani S, Frikstad KM, Patzke S, Zimmermann T, Dogterom M, Akhmanova A (2023)
CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side
J Cell Biol, 222 (4)
DOI 10.1083/jcb.202208062, PubMed 36752787
van Royen ME, Soekmadji C, Grange C, Webber JP, Tertel T, Droste M, Buescher A, Giebel B, Jenster GW, Llorente A, Blijdorp CJ, Burger D, Erdbrügger U, Martens-Uzunova ES (2023)
The quick reference card "Storage of urinary EVs" - A practical guideline tool for research and clinical laboratories
J Extracell Vesicles, 12 (3), e12286
DOI 10.1002/jev2.12286, PubMed 36916183
Zhen Y, Stenmark H (2023)
Autophagosome Biogenesis
Cells, 12 (4)
DOI 10.3390/cells12040668, PubMed 36831335
Zhen Y, Stenmark H (2023)
A phosphoinositide kinase triggers migrasome formation
Cell Res, 33 (8), 577-578
DOI 10.1038/s41422-023-00822-2, PubMed 37165066

Publications 2022

Arora A, Kivelä AM, Wang L, Minkeviciene R, Taskinen JH, Zhang B, Koponen A, Sun J, Shirane M, Zhou Y, Hotulainen P, Raiborg C, Olkkonen VM (2022)
Protrudin regulates FAK activation, endothelial cell migration and angiogenesis
Cell Mol Life Sci, 79 (4), 220
DOI 10.1007/s00018-022-04251-z, PubMed 35368213
Blijdorp CJ, Burger D, Llorente A, Martens-Uzunova ES, Erdbrügger U (2022)
Extracellular Vesicles as Novel Players in Kidney Disease
J Am Soc Nephrol, 33 (3), 467-471
DOI 10.1681/ASN.2021091232, PubMed 35131841
Bousquet PA, Manna D, Sandvik JA, Arntzen MØ, Moreno E, Sandvig K, Krengel U (2022)
SILAC-based quantitative proteomics and microscopy analysis of cancer cells treated with the N-glycolyl GM3-specific anti-tumor antibody 14F7
Front Immunol, 13, 994790
DOI 10.3389/fimmu.2022.994790, PubMed 36439103
Doncheva AI, Romero S, Ramirez-Garrastacho M, Lee S, Kolnes KJ, Tangen DS, Olsen T, Drevon CA, Llorente A, Dalen KT, Hjorth M (2022)
Extracellular vesicles and microRNAs are altered in response to exercise, insulin sensitivity and overweight
Acta Physiol (Oxf), 236 (4), e13862
DOI 10.1111/apha.13862, PubMed 36377504
Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML (2022)
Measuring Autophagic Cargo Flux with Keima-Based Probes
Methods Mol Biol, 2445, 99-115
DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988
Espeland K, Kleinauskas A, Juzenas P, Brech A, Darvekar S, Vasovic V, Warloe T, Christensen E, Jahnsen J, Peng Q (2022)
Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells
Biomedicines, 10 (2)
DOI 10.3390/biomedicines10020232, PubMed 35203441
Fiorito E, Szybowska P, Haugsten EM, Kostas M, Øy GF, Wiedlocha A, Singh S, Nakken S, Mælandsmo GM, Fletcher JA, Meza-Zepeda LA, Wesche J (2022)
Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
Br J Cancer, 127 (11), 1939-1953
DOI 10.1038/s41416-022-01973-6, PubMed 36097178
Frikstad KM, Schink KO, Gilani S, Pedersen LB, Patzke S (2022)
3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines
Bio Protoc, 12 (6), e4360
DOI 10.21769/BioProtoc.4360, PubMed 35434191
Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2022)
Corrigendum to "Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft", [Journal of Control Release, 293 (2019) 183-192]
J Control Release, 349, 1
DOI 10.1016/j.jconrel.2022.06.040, PubMed 35792388
Garcia-Garcia J, Berge AKM, Overå KS, Larsen KB, Bhujabal Z, Brech A, Abudu YP, Lamark T, Johansen T, Sjøttem E (2022)
TRIM27 is an autophagy substrate facilitating mitochondria clustering and mitophagy via phosphorylated TBK1
FEBS J, 290 (4), 1096-1116
DOI 10.1111/febs.16628, PubMed 36111389
Lampart A, Sluzalska KD, Czyrek A, Szerszen A, Otlewski J, Wiedlocha A, Zakrzewska M (2022)
Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells
Cells, 11 (3)
DOI 10.3390/cells11030522, PubMed 35159330
Lobert VH, Skardal ML, Malerød L, Simensen JE, Algra HA, Andersen AN, Fleischer T, Enserink HA, Liestøl K, Heath JK, Rusten TE, Stenmark HA (2022)
PHLPP1 regulates CFTR activity and lumen expansion through AMPK
Development, 149 (20)
DOI 10.1242/dev.200955, PubMed 35997536
Mateus D, Wiedlocha A (2022)
FGF-FGFR signaling promotes the development of invasive cervical cancer
FEBS J, 289 (12), 3419-3421
DOI 10.1111/febs.16384, PubMed 35146913
Mezzasoma L, Bellezza I, Orvietani P, Manni G, Gargaro M, Sagini K, Llorente A, Scarpelli P, Pascucci L, Cellini B, Talesa VN, Fallarino F, Romani R (2022)
Amniotic fluid stem cell-derived extracellular vesicles are independent metabolic units capable of modulating inflammasome activation in THP-1 cells
FASEB J, 36 (4), e22218
DOI 10.1096/fj.202101657R, PubMed 35218567
Migliano SM, Stenmark H (2022)
ESCRTed resistance to T cell attack
Trends Immunol, 43 (8), 598-600
DOI 10.1016/j.it.2022.06.007, PubMed 35810056
Migliano SM, Wenzel EM, Stenmark H (2022)
Biophysical and molecular mechanisms of ESCRT functions, and their implications for disease
Curr Opin Cell Biol, 75, 102062
DOI 10.1016/j.ceb.2022.01.007, PubMed 35248976
Ng MYW, Charsou C, Lapao A, Singh S, Trachsel-Moncho L, Schultz SW, Nakken S, Munson MJ, Simonsen A (2022)
The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
Nat Commun, 13 (1), 6283
DOI 10.1038/s41467-022-33933-2, PubMed 36270994
Nissen-Meyer J, Skotland T, Boye E (2022)
Are doping tests in sports trustworthy?: Athletes suffer from insufficiently defined criteria for doping tests: Athletes suffer from insufficiently defined criteria for doping tests
EMBO Rep, 23 (3), e54431
DOI 10.15252/embr.202154431, PubMed 35156749
Radulovic M, Wenzel EM, Gilani S, Holland LK, Lystad AH, Phuyal S, Olkkonen VM, Brech A, Jäättelä M, Maeda K, Raiborg C, Stenmark H (2022)
Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
EMBO J, 41 (24), e112677
DOI 10.15252/embj.2022112677, PubMed 36408828
Romaine A, Melleby AO, Alam J, Lobert VH, Lu N, Lockwood FE, Hasic A, Lunde IG, Sjaastad I, Stenmark H, Herum KM, Gullberg D, Christensen G (2022)
Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart
Am J Physiol Heart Circ Physiol, 322 (6), H1057-H1071
DOI 10.1152/ajpheart.00635.2021, PubMed 35522553
Sandvig K, Kavaliauskiene S, Myrann AG, Iversen TG, Skotland T (2022)
Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC
Toxins (Basel), 14 (5)
DOI 10.3390/toxins14050360, PubMed 35622606
Skotland T, Iversen TG, Llorente A, Sandvig K (2022)
Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges
Adv Drug Deliv Rev, 186, 114326
DOI 10.1016/j.addr.2022.114326, PubMed 35588953
Skotland T, Sandvig K (2022)
Need for more focus on lipid species in studies of biological and model membranes
Prog Lipid Res, 86, 101160
DOI 10.1016/j.plipres.2022.101160, PubMed 35288150
Wenzel EM, Elfmark LA, Stenmark H, Raiborg C (2022)
ER as master regulator of membrane trafficking and organelle function
J Cell Biol, 221 (10)
DOI 10.1083/jcb.202205135, PubMed 36108241
Wenzel EM, Raiborg C (2022)
ER-endosome contacts master the ins and outs of secretory endosomes
J Cell Biol, 221 (12)
DOI 10.1083/jcb.202210033, PubMed 36355088
Zendrini A, Guerra G, Sagini K, Vagner T, Di Vizio D, Bergese P (2022)
On the surface-to-bulk partition of proteins in extracellular vesicles
Colloids Surf B Biointerfaces, 218, 112728
DOI 10.1016/j.colsurfb.2022.112728, PubMed 35969923

Publications 2021

Agudo-Canalejo J, Schultz SW, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, May AI, Mizushima N, Knorr RL (2021)
Wetting regulates autophagy of phase-separated compartments and the cytosol
Nature, 591 (7848), 142-146
DOI 10.1038/s41586-020-2992-3, PubMed 33473217
Anda S, Boye E, Schink KO, Grallert B (2021)
Cosegregation of asymmetric features during cell division
Open Biol, 11 (8), 210116
DOI 10.1098/rsob.210116, PubMed 34343465
Fernandes P, Miotto B, Saint-Ruf C, Said M, Barra V, Nähse V, Ravera S, Cappelli E, Naim V (2021)
FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
Commun Biol, 4 (1), 127
DOI 10.1038/s42003-021-01647-8, PubMed 33514811
Khezri R, Holland P, Schoborg TA, Abramovich I, Takáts S, Dillard C, Jain A, O'Farrell F, Schultz SW, Hagopian WM, Quintana EM, Ng R, Katheder NS, Rahman MM, Teles Reis JG, Brech A, Jasper H, Rusan NM, Jahren AH, Gottlieb E, Rusten TE (2021)
Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
EMBO J, 40 (18), e107336
DOI 10.15252/embj.2020107336, PubMed 34309071
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹
Autophagy, 17 (1), 1-382
DOI 10.1080/15548627.2020.1797280, PubMed 33634751
Krzyscik MA, Zakrzewska M, Sørensen V, Øy GF, Brunheim S, Haugsten EM, Mælandsmo GM, Wiedlocha A, Otlewski J (2021)
Fibroblast Growth Factor 2 Conjugated with Monomethyl Auristatin E Inhibits Tumor Growth in a Mouse Model
Biomacromolecules, 22 (10), 4169-4180
DOI 10.1021/acs.biomac.1c00662, PubMed 34542998
Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A (2021)
GAK and PRKCD are positive regulators of PRKN-independent mitophagy
Nat Commun, 12 (1), 6101
DOI 10.1038/s41467-021-26331-7, PubMed 34671015
Mygland L, Brinch SA, Strand MF, Olsen PA, Aizenshtadt A, Lund K, Solberg NT, Lycke M, Thorvaldsen TE, Espada S, Misaghian D, Page CM, Agafonov O, Nygård S, Chi NW, Lin E, Tan J, Yu Y, Costa M, Krauss S, Waaler J (2021)
Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
iScience, 24 (7), 102807
DOI 10.1016/j.isci.2021.102807, PubMed 34337362
Nowosielska EM, Cheda A, Pociegiel M, Cheda L, Szymański P, Wiedlocha A (2021)
Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice
Int J Mol Sci, 22 (12)
DOI 10.3390/ijms22126309, PubMed 34208396
Ravussin A, Brech A, Tooze SA, Stenmark H (2021)
The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy
J Cell Sci, 134 (3)
DOI 10.1242/jcs.250670, PubMed 33468622
Schink KO, Tan KW, Spangenberg H, Martorana D, Sneeggen M, Stévenin V, Enninga J, Campsteijn C, Raiborg C, Stenmark H (2021)
The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes
Nat Commun, 12 (1), 6577
DOI 10.1038/s41467-021-26775-x, PubMed 34772942
Schultz SW, Agudo-Canalejo J, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, Mizushima N, Knorr RL, May AI (2021)
Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
Autophagy, 17 (4), 1046-1048
DOI 10.1080/15548627.2021.1887548, PubMed 33629888
Szybowska P, Kostas M, Wesche J, Haugsten EM, Wiedlocha A (2021)
Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
Cells, 10 (6)
DOI 10.3390/cells10061342, PubMed 34071546
Tan KW (2021)
First person - Kia Wee Tan
J. Cell Sci., 134 (14), jcs259055
DOI 10.1242/jcs.259055
Tan KW, Nähse V, Campsteijn C, Brech A, Schink KO, Stenmark H (2021)
JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes
J Cell Sci, 134 (14)
DOI 10.1242/jcs.258495, PubMed 34109410
Valko A, Perez-Pandolfo S, Sorianello E, Brech A, Wappner P, Melani M (2021)
Adaptation to hypoxia in Drosophila melanogaster requires autophagy
Autophagy, 18 (4), 909-920
DOI 10.1080/15548627.2021.1991191, PubMed 34793268
Weisheit S, Wegner CS, Ailte I, Radulovic M, Weyergang A, Selbo PK, Brech A (2021)
Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
Biochem Pharmacol, 194, 114837
DOI 10.1016/j.bcp.2021.114837, PubMed 34780750
Wiedlocha A, Haugsten EM, Zakrzewska M (2021)
Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation
Cells, 10 (9)
DOI 10.3390/cells10092231, PubMed 34571880
Zdżalik-Bielecka D, Poświata A, Kozik K, Jastrzębski K, Schink KO, Brewińska-Olchowik M, Piwocka K, Stenmark H, Miączyńska M (2021)
The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion
Proc Natl Acad Sci U S A, 118 (28)
DOI 10.1073/pnas.2024596118, PubMed 34244439
Zhen Y, Radulovic M, Vietri M, Stenmark H (2021)
Sealing holes in cellular membranes
EMBO J, 40 (7), e106922
DOI 10.15252/embj.2020106922, PubMed 33644904

Publications 2020

Dillard P, Lie M, Baken E, Lobert VH, Benard E, Köksal H, Inderberg EM, Wälchli S (2020)
Colorectal cysts as a validating tool for CAR therapy
BMC Biotechnol, 20 (1), 30
DOI 10.1186/s12896-020-00623-0, PubMed 32487146
Jakobi AJ, Huber ST, Mortensen SA, Schultz SW, Palara A, Kuhm T, Shrestha BK, Lamark T, Hagen WJH, Wilmanns M, Johansen T, Brech A, Sachse C (2020)
Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake
Nat Commun, 11 (1), 440
DOI 10.1038/s41467-020-14343-8, PubMed 31974402
Jendryczko K, Chudzian J, Skinder N, Opaliński Ł, Rzeszótko J, Wiedlocha A, Otlewski J, Szlachcic A (2020)
FGF2-Derived PeptibodyF2-MMAE Conjugate for Targeted Delivery of Cytotoxic Drugs into Cancer Cells Overexpressing FGFR1
Cancers (Basel), 12 (10)
DOI 10.3390/cancers12102992, PubMed 33076489
Laiouar S, Berns N, Brech A, Riechmann V (2020)
RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism
Curr Biol, 30 (7), 1177-1188.e5
DOI 10.1016/j.cub.2020.01.048, PubMed 32059769
Liese S, Wenzel EM, Kjos I, Rojas Molina R, Schultz SW, Brech A, Stenmark H, Raiborg C, Carlson A (2020)
Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles
Proc Natl Acad Sci U S A, 117 (46), 28614-28624
DOI 10.1073/pnas.2014228117, PubMed 33139578
Munthe E, Raiborg C, Stenmark H, Wenzel EM (2020)
Clathrin regulates Wnt/β-catenin signaling by affecting Golgi to plasma membrane transport of transmembrane proteins
J Cell Sci, 133 (13)
DOI 10.1242/jcs.244467, PubMed 32546530
Ohnstad AE, Delgado JM, North BJ, Nasa I, Kettenbach AN, Schultz SW, Shoemaker CJ (2020)
Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
EMBO J, 39 (24), e104948
DOI 10.15252/embj.2020104948, PubMed 33226137
Palušová V, Renzová T, Verlande A, Vaclová T, Medková M, Cetlová L, Sedláčková M, Hříbková H, Slaninová I, Krutá M, Rotrekl V, Uhlířová H, Křížová A, Chmelík R, Veselý P, Krafčíková M, Trantírek L, Schink KO, Uldrijan S (2020)
Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds
Cancers (Basel), 12 (6)
DOI 10.3390/cancers12061516, PubMed 32531927
Pedersen NM, Wenzel EM, Wang L, Antoine S, Chavrier P, Stenmark H, Raiborg C (2020)
Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion
J Cell Biol, 219 (8)
DOI 10.1083/jcb.202003063, PubMed 32479595
Radulovic M, Stenmark H (2020)
LRRK2 to the rescue of damaged endomembranes
EMBO J, 39 (18), e106162
DOI 10.15252/embj.2020106162, PubMed 32803793
Vietri M, Schultz SW, Bellanger A, Jones CM, Petersen LI, Raiborg C, Skarpen E, Pedurupillay CRJ, Kjos I, Kip E, Timmer R, Jain A, Collas P, Knorr RL, Grellscheid SN, Kusumaatmaja H, Brech A, Micci F, Stenmark H, Campsteijn C (2020)
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
Nat Cell Biol, 22 (7), 856-867
DOI 10.1038/s41556-020-0537-5, PubMed 32601372
Wong JJW, Berstad MB, Fremstedal ASV, Berg K, Patzke S, Sørensen V, Peng Q, Selbo PK, Weyergang A (2020)
Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy
Cancers (Basel), 12 (2)
DOI 10.3390/cancers12020417, PubMed 32053965
Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
STEEP mediates STING ER exit and activation of signaling
Nat Immunol, 21 (8), 868-879
DOI 10.1038/s41590-020-0730-5, PubMed 32690950
Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
Author Correction: STEEP mediates STING ER exit and activation of signaling
Nat Immunol, 21 (11), 1468-1469
DOI 10.1038/s41590-020-0803-5, PubMed 32929276

Publications 2019

Brison O, El-Hilali S, Azar D, Koundrioukoff S, Schmidt M, Nähse V, Jaszczyszyn Y, Lachages AM, Dutrillaux B, Thermes C, Debatisse M, Chen CL (2019)
Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide
Nat Commun, 10 (1), 5693
DOI 10.1038/s41467-019-13674-5, PubMed 31836700
Frikstad KM, Molinari E, Thoresen M, Ramsbottom SA, Hughes F, Letteboer SJF, Gilani S, Schink KO, Stokke T, Geimer S, Pedersen LB, Giles RH, Akhmanova A, Roepman R, Sayer JA, Patzke S (2019)
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
Cell Rep, 28 (7), 1907-1922.e6
DOI 10.1016/j.celrep.2019.07.025, PubMed 31412255
Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ (2019)
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
Nat Commun, 10 (1), 514
DOI 10.1038/s41467-019-08384-x, PubMed 30705279
Hoem G, Bowitz Larsen K, Øvervatn A, Brech A, Lamark T, Sjøttem E, Johansen T (2019)
The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS
Front Genet, 10, 249
DOI 10.3389/fgene.2019.00249, PubMed 30984240
Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen JC, Eibes S, Maiani E, Harder LM, Wesch N, Foged MM, Maeda K, Nazio F, de la Ballina LR, Dötsch V, Brech A, Frankel LB, Jäättelä M, Locatelli F, Barisic M, Andersen JS, Bekker-Jensen S, Lund AH, Rogov VV, Papaleo E et al. (2019)
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites
Nat Commun, 10 (1), 4176
DOI 10.1038/s41467-019-12094-9, PubMed 31519908
Lie-Jensen A, Ivanauskiene K, Malerød L, Jain A, Tan KW, Laerdahl JK, Liestøl K, Stenmark H, Haglund K (2019)
Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
Curr Biol, 29 (20), 3538-3548.e7
DOI 10.1016/j.cub.2019.09.025, PubMed 31607533
Luhr M, Torgersen ML, Szalai P, Hashim A, Brech A, Staerk J, Engedal N (2019)
The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress
J Biol Chem, 294 (20), 8197-8217
DOI 10.1074/jbc.RA118.002829, PubMed 30926605
Palomo-Guerrero M, Fadó R, Casas M, Pérez-Montero M, Baena M, Helmer PO, Domínguez JL, Roig A, Serra D, Hayen H, Stenmark H, Raiborg C, Casals N (2019)
Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
Elife, 8
DOI 10.7554/eLife.51063, PubMed 31868590
Pölönen P, Jawahar Deen A, Leinonen HM, Jyrkkänen HK, Kuosmanen S, Mononen M, Jain A, Tuomainen T, Pasonen-Seppänen S, Hartikainen JM, Mannermaa A, Nykter M, Tavi P, Johansen T, Heinäniemi M, Levonen AL (2019)
Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma
Oncogene, 38 (50), 7473-7490
DOI 10.1038/s41388-019-0956-6, PubMed 31444413
Shoemaker CJ, Huang TQ, Weir NR, Polyakov NJ, Schultz SW, Denic V (2019)
CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor
PLoS Biol, 17 (4), e2007044
DOI 10.1371/journal.pbio.2007044, PubMed 30933966
Skjesol A, Yurchenko M, Bösl K, Gravastrand C, Nilsen KE, Grøvdal LM, Agliano F, Patane F, Lentini G, Kim H, Teti G, Kumar Sharma A, Kandasamy RK, Sporsheim B, Starheim KK, Golenbock DT, Stenmark H, McCaffrey M, Espevik T, Husebye H (2019)
The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
PLoS Pathog, 15 (3), e1007684
DOI 10.1371/journal.ppat.1007684, PubMed 30883606
Sneeggen M, Pedersen NM, Campsteijn C, Haugsten EM, Stenmark H, Schink KO (2019)
WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
Nat Commun, 10 (1), 2850
DOI 10.1038/s41467-019-10794-w, PubMed 31253801
Sneeggen M, Schink KO, Stenmark H (2019)
Tumor suppression by control of matrix metalloproteinase recycling
Mol Cell Oncol, 6 (6), e1646606
DOI 10.1080/23723556.2019.1646606, PubMed 31692886
Szybowska P, Kostas M, Wesche J, Wiedlocha A, Haugsten EM (2019)
Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway
Cells, 8 (6)
DOI 10.3390/cells8060518, PubMed 31146385
Theodossiou TA, Ali M, Grigalavicius M, Grallert B, Dillard P, Schink KO, Olsen CE, Wälchli S, Inderberg EM, Kubin A, Peng Q, Berg K (2019)
Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
NPJ Breast Cancer, 5, 13
DOI 10.1038/s41523-019-0108-8, PubMed 30993194
Vietri M, Radulovic M, Stenmark H (2019)
The many functions of ESCRTs
Nat Rev Mol Cell Biol, 21 (1), 25-42
DOI 10.1038/s41580-019-0177-4, PubMed 31705132
Zakrzewska M, Opalinski L, Haugsten EM, Otlewski J, Wiedlocha A (2019)
Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling
Int J Mol Sci, 20 (8)
DOI 10.3390/ijms20081826, PubMed 31013829
Zhen Y, Spangenberg H, Munson MJ, Brech A, Schink KO, Tan KW, Sørensen V, Wenzel EM, Radulovic M, Engedal N, Simonsen A, Raiborg C, Stenmark H (2019)
ESCRT-mediated phagophore sealing during mitophagy
Autophagy, 16 (5), 826-841
DOI 10.1080/15548627.2019.1639301, PubMed 31366282

Publications 2018

Hurem S, Gomes T, Brede DA, Mayer I, Lobert VH, Mutoloki S, Gutzkow KB, Teien HC, Oughton D, Aleström P, Lyche JL (2018)
Gamma irradiation during gametogenesis in young adult zebrafish causes persistent genotoxicity and adverse reproductive effects
Ecotoxicol Environ Saf, 154, 19-26
DOI 10.1016/j.ecoenv.2018.02.031, PubMed 29453161
Kostas M, Haugsten EM, Zhen Y, Sørensen V, Szybowska P, Fiorito E, Lorenz S, Jones N, de Souza GA, Wiedlocha A, Wesche J (2018)
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
Mol Cell Proteomics, 17 (5), 850-870
DOI 10.1074/mcp.RA117.000538, PubMed 29371290
Kostas M, Lampart A, Bober J, Wiedlocha A, Tomala J, Krowarsch D, Otlewski J, Zakrzewska M (2018)
Translocation of Exogenous FGF1 and FGF2 Protects the Cell against Apoptosis Independently of Receptor Activation
J Mol Biol, 430 (21), 4087-4101
DOI 10.1016/j.jmb.2018.08.004, PubMed 30099027
Malerød L, Le Borgne R, Lie-Jensen A, Eikenes ÅH, Brech A, Liestøl K, Stenmark H, Haglund K (2018)
Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics
EMBO J, 37 (13)
DOI 10.15252/embj.201797741, PubMed 29858227
Mejlvang J, Olsvik H, Svenning S, Bruun JA, Abudu YP, Larsen KB, Brech A, Hansen TE, Brenne H, Hansen T, Stenmark H, Johansen T (2018)
Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
J Cell Biol, 217 (10), 3640-3655
DOI 10.1083/jcb.201711002, PubMed 30018090
Norum JH, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, Sørlie T (2018)
The tankyrase inhibitor G007-LK inhibits small intestine LGR5⁺ stem cell proliferation without altering tissue morphology
Biol Res, 51 (1), 3
DOI 10.1186/s40659-017-0151-6, PubMed 29316982
Olsvik HL, Svenning S, Abudu YP, Brech A, Stenmark H, Johansen T, Mejlvang J (2018)
Endosomal microautophagy is an integrated part of the autophagic response to amino acid starvation
Autophagy, 15 (1), 182-183
DOI 10.1080/15548627.2018.1532265, PubMed 30295124
Radulovic M, Schink KO, Wenzel EM, Nähse V, Bongiovanni A, Lafont F, Stenmark H (2018)
ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival
EMBO J, 37 (21)
DOI 10.15252/embj.201899753, PubMed 30314966
Radulovic M, Stenmark H (2018)
ESCRTs in membrane sealing
Biochem Soc Trans, 46 (4), 773-778
DOI 10.1042/BST20170435, PubMed 29903934
Vietri M, Stenmark H (2018)
Orchestrating Nuclear Envelope Sealing during Mitosis
Dev Cell, 47 (5), 541-542
DOI 10.1016/j.devcel.2018.11.020, PubMed 30513298
Wenzel EM, Schultz SW, Schink KO, Pedersen NM, Nähse V, Carlson A, Brech A, Stenmark H, Raiborg C (2018)
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
Nat Commun, 9 (1), 2932
DOI 10.1038/s41467-018-05345-8, PubMed 30050131
Zhen Y, Haugsten EM, Singh SK, Wesche J (2018)
Proximity Labeling by a Recombinant APEX2-FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4
Biochemistry, 57 (26), 3807-3816
DOI 10.1021/acs.biochem.8b00120, PubMed 29812912

Publications 2017

Ailte I, Lingelem AB, Kvalvaag AS, Kavaliauskiene S, Brech A, Koster G, Dommersnes PG, Bergan J, Skotland T, Sandvig K (2017)
Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
Traffic, 18 (3), 176-191
DOI 10.1111/tra.12468, PubMed 28067430
Fosdahl AM, Dietrich M, Schink KO, Malik MS, Skeie M, Bertelsen V, Stang E (2017)
ErbB3 interacts with Hrs and is sorted to lysosomes for degradation
Biochim Biophys Acta Mol Cell Res, 1864 (12), 2241-2252
DOI 10.1016/j.bbamcr.2017.08.011, PubMed 28867611
Hong Z, Pedersen NM, Wang L, Torgersen ML, Stenmark H, Raiborg C (2017)
PtdIns3P controls mTORC1 signaling through lysosomal positioning
J Cell Biol, 216 (12), 4217-4233
DOI 10.1083/jcb.201611073, PubMed 29030394
Katheder NS, Khezri R, O'Farrell F, Schultz SW, Jain A, Rahman MM, Schink KO, Theodossiou TA, Johansen T, Juhász G, Bilder D, Brech A, Stenmark H, Rusten TE (2017)
Microenvironmental autophagy promotes tumour growth
Nature, 541 (7637), 417-420
DOI 10.1038/nature20815, PubMed 28077876
Katheder NS, Rusten TE (2017)
Microenvironment and tumors-a nurturing relationship
Autophagy, 13 (7), 1241-1243
DOI 10.1080/15548627.2017.1310361, PubMed 28632995
Krzyscik MA, Zakrzewska M, Sørensen V, Sokolowska-Wedzina A, Lobocki M, Swiderska KW, Krowarsch D, Wiedlocha A, Otlewski J (2017)
Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors
ACS Omega, 2 (7), 3792-3805
DOI 10.1021/acsomega.7b00116, PubMed 30023704
Lång A, Eriksson J, Schink KO, Lång E, Blicher P, Połeć A, Brech A, Dalhus B, Bøe SO (2017)
Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites
Nucleus, 8 (4), 404-420
DOI 10.1080/19491034.2017.1306161, PubMed 28402725
O'Farrell F, Lobert VH, Sneeggen M, Jain A, Katheder NS, Wenzel EM, Schultz SW, Tan KW, Brech A, Stenmark H, Rusten TE (2017)
Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation
Nat Cell Biol, 19 (12), 1412-1423
DOI 10.1038/ncb3631, PubMed 29084199
Olsen CE, Weyergang A, Edwards VT, Berg K, Brech A, Weisheit S, Høgset A, Selbo PK (2017)
Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
Biochem Pharmacol, 144, 63-77
DOI 10.1016/j.bcp.2017.08.002, PubMed 28784290
Raiborg C, Schink KO, Stenmark H (2017)
Suppressing mTORC1 on the lysosome
EMBO J, 36 (13), 1809-1810
DOI 10.15252/embj.201797469, PubMed 28623241
Thorvaldsen TE (2017)
Targeting Tankyrase to Fight WNT-dependent Tumours
Basic Clin Pharmacol Toxicol, 121 (2), 81-88
DOI 10.1111/bcpt.12786, PubMed 28371398
Thorvaldsen TE, Pedersen NM, Wenzel EM, Stenmark H (2017)
Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation
PLoS One, 12 (1), e0170508
DOI 10.1371/journal.pone.0170508, PubMed 28107521
Totland MZ, Bergsland CH, Fykerud TA, Knudsen LM, Rasmussen NL, Eide PW, Yohannes Z, Sørensen V, Brech A, Lothe RA, Leithe E (2017)
The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions
J Cell Sci, 130 (17), 2867-2882
DOI 10.1242/jcs.202408, PubMed 28733455

Publications 2016

Campsteijn C, Vietri M, Stenmark H (2016)
Novel ESCRT functions in cell biology: spiraling out of control?
Curr Opin Cell Biol, 41, 1-8
DOI 10.1016/j.ceb.2016.03.008, PubMed 27031044
Christ L, Raiborg C, Wenzel EM, Campsteijn C, Stenmark H (2016)
Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery
Trends Biochem Sci, 42 (1), 42-56
DOI 10.1016/j.tibs.2016.08.016, PubMed 27669649
Christ L, Wenzel EM, Liestøl K, Raiborg C, Campsteijn C, Stenmark H (2016)
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission
J Cell Biol, 212 (5), 499-513
DOI 10.1083/jcb.201507009, PubMed 26929449
Fykerud TA, Knudsen LM, Totland MZ, Sørensen V, Dahal-Koirala S, Lothe RA, Brech A, Leithe E (2016)
Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding
Cell Cycle, 15 (21), 2943-2957
DOI 10.1080/15384101.2016.1231280, PubMed 27625181
Halsne R, Tandberg JI, Lobert VH, Østby GC, Thoen E, Ropstad E, Verhaegen S (2016)
Effects of perfluorinated alkyl acids on cellular responses of MCF-10A mammary epithelial cells in monolayers and on acini formation in vitro
Toxicol Lett, 259, 95-107
DOI 10.1016/j.toxlet.2016.08.004, PubMed 27511595
Haugsten EM, Sørensen V, Kunova Bosakova M, de Souza GA, Krejci P, Wiedlocha A, Wesche J (2016)
Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport
J Proteome Res, 15 (10), 3841-3855
DOI 10.1021/acs.jproteome.6b00652, PubMed 27615514
Hessvik NP, Øverbye A, Brech A, Torgersen ML, Jakobsen IS, Sandvig K, Llorente A (2016)
PIKfyve inhibition increases exosome release and induces secretory autophagy
Cell Mol Life Sci, 73 (24), 4717-4737
DOI 10.1007/s00018-016-2309-8, PubMed 27438886
Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A (2016)
HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
Nat Commun, 7, 13889
DOI 10.1038/ncomms13889, PubMed 28004827
Lie-Jensen A, Haglund K (2016)
Antibody Staining in Drosophila Germaria
Methods Mol Biol, 1457, 19-33
DOI 10.1007/978-1-4939-3795-0_3, PubMed 27557571
Lobert VH, Mouradov D, Heath JK (2016)
Focusing the Spotlight on the Zebrafish Intestine to Illuminate Mechanisms of Colorectal Cancer
Adv Exp Med Biol, 916, 411-37
DOI 10.1007/978-3-319-30654-4_18, PubMed 27165364
Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M (2016)
ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors
Sci Signal, 9 (411), ra8
DOI 10.1126/scisignal.aad0848, PubMed 26787452
Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V (2016)
TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
J Cell Sci, 129 (19), 3562-3573
DOI 10.1242/jcs.190017, PubMed 27562068
Nähse V, Christ L, Stenmark H, Campsteijn C (2016)
The Abscission Checkpoint: Making It to the Final Cut
Trends Cell Biol, 27 (1), 1-11
DOI 10.1016/j.tcb.2016.10.001, PubMed 27810282
Pedersen NM, Thorvaldsen TE, Schultz SW, Wenzel EM, Stenmark H (2016)
Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity
PLoS One, 11 (8), e0160507
DOI 10.1371/journal.pone.0160507, PubMed 27482906
Puvirajesinghe TM, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, Sebbagh M, Lopez M, Brech A, Finetti P, Charafe-Jauffret E, Chaffanet M, Castellano R, Restouin A, Marchetto S, Collette Y, Gonçalvès A, Macara I, Birnbaum D, Kodjabachian L, Johansen T, Borg JP (2016)
Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer
Nat Commun, 7, 10318
DOI 10.1038/ncomms10318, PubMed 26754771
Raiborg C, Stenmark H (2016)
Plasma membrane repairs by small GTPase Rab3a
J Cell Biol, 213 (6), 613-5
DOI 10.1083/jcb.201606006, PubMed 27325788
Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
Phosphoinositides in membrane contact sites
Biochem Soc Trans, 44 (2), 425-30
DOI 10.1042/BST20150190, PubMed 27068950
Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
ER-endosome contact sites in endosome positioning and protrusion outgrowth
Biochem Soc Trans, 44 (2), 441-6
DOI 10.1042/BST20150246, PubMed 27068952
Schink KO, Tan KW, Stenmark H (2016)
Phosphoinositides in Control of Membrane Dynamics
Annu Rev Cell Dev Biol, 32, 143-171
DOI 10.1146/annurev-cellbio-111315-125349, PubMed 27576122
Schmid MR, Anderl I, Vo HT, Valanne S, Yang H, Kronhamn J, Rämet M, Rusten TE, Hultmark D (2016)
Genetic Screen in Drosophila Larvae Links ird1 Function to Toll Signaling in the Fat Body and Hemocyte Motility
PLoS One, 11 (7), e0159473
DOI 10.1371/journal.pone.0159473, PubMed 27467079
Sundvold H, Sundvold-Gjerstad V, Malerød-Fjeld H, Haglund K, Stenmark H, Malerød L (2016)
Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow
Cell Cycle, 15 (5), 628-43
DOI 10.1080/15384101.2016.1146834, PubMed 27104745
Szymanska M, Fosdahl AM, Raiborg C, Dietrich M, Liestøl K, Stang E, Bertelsen V (2016)
Interaction with epsin 1 regulates the constitutive clathrin-dependent internalization of ErbB3
Biochim Biophys Acta, 1863 (6 Pt A), 1179-88
DOI 10.1016/j.bbamcr.2016.03.011, PubMed 26975582
Vietri M, Stenmark H, Campsteijn C (2016)
Closing a gap in the nuclear envelope
Curr Opin Cell Biol, 40, 90-97
DOI 10.1016/j.ceb.2016.03.001, PubMed 27016712

Publications 2015

Bauereiss A, Welzel O, Jung J, Grosse-Holz S, Lelental N, Lewczuk P, Wenzel EM, Kornhuber J, Groemer TW (2015)
Surface Trafficking of APP and BACE in Live Cells
Traffic, 16 (6), 655-75
DOI 10.1111/tra.12270, PubMed 25712587
Buchtova M, Chaloupkova R, Zakrzewska M, Vesela I, Cela P, Barathova J, Gudernova I, Zajickova R, Trantirek L, Martin J, Kostas M, Otlewski J, Damborsky J, Kozubik A, Wiedlocha A, Krejci P (2015)
Instability restricts signaling of multiple fibroblast growth factors
Cell Mol Life Sci, 72 (12), 2445-59
DOI 10.1007/s00018-015-1856-8, PubMed 25854632
Drießen S, Berleth N, Friesen O, Löffler AS, Böhler P, Hieke N, Stuhldreier F, Peter C, Schink KO, Schultz SW, Stenmark H, Holland P, Simonsen A, Wesselborg S, Stork B (2015)
Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy
Autophagy, 11 (9), 1458-70
DOI 10.1080/15548627.2015.1067359, PubMed 26207339
Egeland EV, Boye K, Pettersen SJ, Haugen MH, Øyjord T, Malerød L, Flatmark K, Mælandsmo GM (2015)
Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes
Clin Exp Metastasis, 32 (8), 755-67
DOI 10.1007/s10585-015-9742-1, PubMed 26349943
Eikenes ÅH, Malerød L, Christensen AL, Steen CB, Mathieu J, Nezis IP, Liestøl K, Huynh JR, Stenmark H, Haglund K (2015)
ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo
PLoS Genet, 11 (1), e1004904
DOI 10.1371/journal.pgen.1004904, PubMed 25635693
Eikenes ÅH, Malerød L, Lie-Jensen A, Sem Wegner C, Brech A, Liestøl K, Stenmark H, Haglund K (2015)
Src64 controls a novel actin network required for proper ring canal formation in the Drosophila male germline
Development, 142 (23), 4107-18
DOI 10.1242/dev.124370, PubMed 26628094
Helgesen E, Fossum-Raunehaug S, Sætre F, Schink KO, Skarstad K (2015)
Dynamic Escherichia coli SeqA complexes organize the newly replicated DNA at a considerable distance from the replisome
Nucleic Acids Res, 43 (5), 2730-43
DOI 10.1093/nar/gkv146, PubMed 25722374
Jain A, Rusten TE, Katheder N, Elvenes J, Bruun JA, Sjøttem E, Lamark T, Johansen T (2015)
p62/Sequestosome-1, Autophagy-related Gene 8, and Autophagy in Drosophila Are Regulated by Nuclear Factor Erythroid 2-related Factor 2 (NRF2), Independent of Transcription Factor TFEB
J Biol Chem, 290 (24), 14945-62
DOI 10.1074/jbc.M115.656116, PubMed 25931115
Raiborg C, Wenzel EM, Pedersen NM, Olsvik H, Schink KO, Schultz SW, Vietri M, Nisi V, Bucci C, Brech A, Johansen T, Stenmark H (2015)
Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth
Nature, 520 (7546), 234-8
DOI 10.1038/nature14359, PubMed 25855459
Raiborg C, Wenzel EM, Stenmark H (2015)
ER-endosome contact sites: molecular compositions and functions
EMBO J, 34 (14), 1848-58
DOI 10.15252/embj.201591481, PubMed 26041457
Sternemalm J, Geimer S, Frikstad KA, Schink KO, Stokke T, Patzke S (2015)
CSPP-L Associates with the Desmosome of Polarized Epithelial Cells and Is Required for Normal Spheroid Formation
PLoS One, 10 (8), e0134789
DOI 10.1371/journal.pone.0134789, PubMed 26241740
Thorvaldsen TE, Pedersen NM, Wenzel EM, Schultz SW, Brech A, Liestøl K, Waaler J, Krauss S, Stenmark H (2015)
Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes
Mol Cancer Res, 13 (11), 1487-501
DOI 10.1158/1541-7786.MCR-15-0125, PubMed 26124443
Vietri M, Schink KO, Campsteijn C, Wegner CS, Schultz SW, Christ L, Thoresen SB, Brech A, Raiborg C, Stenmark H (2015)
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing
Nature, 522 (7555), 231-5
DOI 10.1038/nature14408, PubMed 26040712
Wendel T, Zhen Y, Suo Z, Bruheim S, Wiedlocha A (2015)
The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo
Exp Cell Res, 340 (2), 220-6
DOI 10.1016/j.yexcr.2015.12.017, PubMed 26748184
Zhen Y, Stenmark H (2015)
Cellular functions of Rab GTPases at a glance
J Cell Sci, 128 (17), 3171-6
DOI 10.1242/jcs.166074, PubMed 26272922
Øvrebø JI, Campsteijn C, Kourtesis I, Hausen H, Raasholm M, Thompson EM (2015)
Functional specialization of chordate CDK1 paralogs during oogenic meiosis
Cell Cycle, 14 (6), 880-93
DOI 10.1080/15384101.2015.1006000, PubMed 25714331

Publications 2014

Danks GB, Raasholm M, Campsteijn C, Long AM, Manak JR, Lenhard B, Thompson EM (2014)
Trans-splicing and operons in metazoans: translational control in maternally regulated development and recovery from growth arrest
Mol Biol Evol, 32 (3), 585-99
DOI 10.1093/molbev/msu336, PubMed 25525214
Demarco RS, Eikenes ÅH, Haglund K, Jones DL (2014)
Investigating spermatogenesis in Drosophila melanogaster
Methods, 68 (1), 218-27
DOI 10.1016/j.ymeth.2014.04.020, PubMed 24798812
Haugsten EM, Brech A, Liestøl K, Norman JC, Wesche J (2014)
Photoactivation approaches reveal a role for Rab11 in FGFR4 recycling and signalling
Traffic, 15 (6), 665-83
DOI 10.1111/tra.12168, PubMed 24589086
Oppelt A, Haugsten EM, Zech T, Danielsen HE, Sveen A, Lobert VH, Skotheim RI, Wesche J (2014)
PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1
Biochem J, 461 (3), 383-90
DOI 10.1042/BJ20140132, PubMed 24840251
Palibrk V, Lång E, Lång A, Schink KO, Rowe AD, Bøe SO (2014)
Promyelocytic leukemia bodies tether to early endosomes during mitosis
Cell Cycle, 13 (11), 1749-55
DOI 10.4161/cc.28653, PubMed 24675887
Phuyal S, Skotland T, Hessvik NP, Simolin H, Øverbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A (2014)
The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
J Biol Chem, 290 (7), 4225-37
DOI 10.1074/jbc.M114.593962, PubMed 25519911
Raiborg C, Stenmark H (2014)
An ER clamp for endosome fission
EMBO J, 34 (2), 136-7
DOI 10.15252/embj.201490707, PubMed 25502456
Reidick C, El Magraoui F, Meyer HE, Stenmark H, Platta HW (2014)
Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO
Cancers (Basel), 7 (1), 1-29
DOI 10.3390/cancers7010001, PubMed 25545884
Sagona AP, Nezis IP, Stenmark H (2014)
Association of CHMP4B and autophagy with micronuclei: implications for cataract formation
Biomed Res Int, 2014, 974393
DOI 10.1155/2014/974393, PubMed 24741567
Salvi M, Raiborg C, Hanson PI, Campsteijn C, Stenmark H, Pinna LA (2014)
CK2 involvement in ESCRT-III complex phosphorylation
Arch Biochem Biophys, 545, 83-91
DOI 10.1016/j.abb.2014.01.006, PubMed 24440309
Sletten T, Kostas M, Bober J, Sorensen V, Yadollahi M, Olsnes S, Tomala J, Otlewski J, Zakrzewska M, Wiedlocha A (2014)
Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1)
PLoS One, 9 (3), e90687
DOI 10.1371/journal.pone.0090687, PubMed 24595027
Stiebler AC, Freitag J, Schink KO, Stehlik T, Tillmann BA, Ast J, Bölker M (2014)
Ribosomal readthrough at a short UGA stop codon context triggers dual localization of metabolic enzymes in Fungi and animals
PLoS Genet, 10 (10), e1004685
DOI 10.1371/journal.pgen.1004685, PubMed 25340584
Thoresen SB, Campsteijn C, Vietri M, Schink KO, Liestøl K, Andersen JS, Raiborg C, Stenmark H (2014)
ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4
Nat Cell Biol, 16 (6), 550-60
DOI 10.1038/ncb2959, PubMed 24814515
Wegner CS, Schink KO, Stenmark H, Brech A (2014)
Monitoring phosphatidylinositol 3-phosphate in multivesicular endosome biogenesis
Methods Enzymol, 534, 3-23
DOI 10.1016/B978-0-12-397926-1.00001-9, PubMed 24359945

Publications 2013

Amoasii L, Hnia K, Chicanne G, Brech A, Cowling BS, Müller MM, Schwab Y, Koebel P, Ferry A, Payrastre B, Laporte J (2013)
Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo
J Cell Sci, 126 (Pt 8), 1806-19
DOI 10.1242/jcs.118505, PubMed 23444364
Bostad M, Berg K, Høgset A, Skarpen E, Stenmark H, Selbo PK (2013)
Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
J Control Release, 168 (3), 317-26
DOI 10.1016/j.jconrel.2013.03.023, PubMed 23567040
Eikenes ÅH, Brech A, Stenmark H, Haglund K (2013)
Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline
Dev Biol, 377 (1), 9-20
DOI 10.1016/j.ydbio.2013.02.021, PubMed 23499247
Haugsten EM, Oppelt A, Wesche J (2013)
Phosphatidylinositol 5-phosphate is a second messenger important for cell migration
Commun Integr Biol, 6 (5), e25446
DOI 10.4161/cib.25446, PubMed 24265857
Henne WM, Stenmark H, Emr SD (2013)
Molecular mechanisms of the membrane sculpting ESCRT pathway
Cold Spring Harb Perspect Biol, 5 (9)
DOI 10.1101/cshperspect.a016766, PubMed 24003212
Isakson P, Lystad AH, Breen K, Koster G, Stenmark H, Simonsen A (2013)
TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
Autophagy, 9 (12), 1955-64
DOI 10.4161/auto.26085, PubMed 24128730
Knævelsrud H, Søreng K, Raiborg C, Håberg K, Rasmuson F, Brech A, Liestøl K, Rusten TE, Stenmark H, Neufeld TP, Carlsson SR, Simonsen A (2013)
Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation
J Cell Biol, 202 (2), 331-49
DOI 10.1083/jcb.201205129, PubMed 23878278
Lueke K, Kaiser T, Svetlitchny A, Welzel O, Wenzel EM, Tyagarajan S, Kornhuber J, Groemer TW (2013)
Basic presynaptic functions in hippocampal neurons are not affected by acute or chronic lithium treatment
J Neural Transm (Vienna), 121 (2), 211-9
DOI 10.1007/s00702-013-1087-9, PubMed 24036894
Nadratowska-Wesolowska B, Haugsten EM, Zakrzewska M, Jakimowicz P, Zhen Y, Pajdzik D, Wesche J, Wiedlocha A (2013)
RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789
Oncogene, 33 (40), 4823-36
DOI 10.1038/onc.2013.425, PubMed 24141780
O Farrell F, Rusten TE, Stenmark H (2013)
Phosphoinositide 3-kinases as accelerators and brakes of autophagy
FEBS J, 280 (24), 6322-37
DOI 10.1111/febs.12486, PubMed 23953235
O'Farrell F, Wang S, Katheder N, Rusten TE, Samakovlis C (2013)
Two-tiered control of epithelial growth and autophagy by the insulin receptor and the ret-like receptor, stitcher
PLoS Biol, 11 (7), e1001612
DOI 10.1371/journal.pbio.1001612, PubMed 23935447
Raiborg C, Schink KO, Stenmark H (2013)
Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic
FEBS J, 280 (12), 2730-42
DOI 10.1111/febs.12116, PubMed 23289851
Schink KO, Raiborg C, Stenmark H (2013)
Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling
Bioessays, 35 (10), 900-12
DOI 10.1002/bies.201300064, PubMed 23881848
Schneikert J, Vijaya Chandra SH, Ruppert JG, Ray S, Wenzel EM, Behrens J (2013)
Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation
PLoS One, 8 (7), e68072
DOI 10.1371/journal.pone.0068072, PubMed 23840886
Shahzidi S, Brech A, Sioud M, Li X, Suo Z, Nesland JM, Peng Q (2013)
Lamin A/C cleavage by caspase-6 activation is crucial for apoptotic induction by photodynamic therapy with hexaminolevulinate in human B-cell lymphoma cells
Cancer Lett, 339 (1), 25-32
DOI 10.1016/j.canlet.2013.07.026, PubMed 23916608
Wu X, Chen JY, Brech A, Fang C, Wang J, Helm PJ, Peng Q (2013)
The use of femto-second lasers to trigger powerful explosions of gold nanorods to destroy cancer cells
Biomaterials, 34 (26), 6157-62
DOI 10.1016/j.biomaterials.2013.04.048, PubMed 23706782
Zakrzewska M, Haugsten EM, Nadratowska-Wesolowska B, Oppelt A, Hausott B, Jin Y, Otlewski J, Wesche J, Wiedlocha A (2013)
ERK-mediated phosphorylation of fibroblast growth factor receptor 1 on Ser777 inhibits signaling
Sci Signal, 6 (262), ra11
DOI 10.1126/scisignal.2003087, PubMed 23405013

Publications 2012

Abrahamsen H, Stenmark H, Platta HW (2012)
Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression
FEBS Lett, 586 (11), 1584-91
DOI 10.1016/j.febslet.2012.04.046, PubMed 22673570
Danks G, Campsteijn C, Parida M, Butcher S, Doddapaneni H, Fu B, Petrin R, Metpally R, Lenhard B, Wincker P, Chourrout D, Thompson EM, Manak JR (2012)
OikoBase: a genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica
Nucleic Acids Res, 41 (Database issue), D845-53
DOI 10.1093/nar/gks1159, PubMed 23185044
Hessvik NP, Phuyal S, Brech A, Sandvig K, Llorente A (2012)
Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells
Biochim Biophys Acta, 1819 (11-12), 1154-63
DOI 10.1016/j.bbagrm.2012.08.016, PubMed 22982408
Huotari J, Meyer-Schaller N, Hubner M, Stauffer S, Katheder N, Horvath P, Mancini R, Helenius A, Peter M (2012)
Cullin-3 regulates late endosome maturation
Proc Natl Acad Sci U S A, 109 (3), 823-8
DOI 10.1073/pnas.1118744109, PubMed 22219362
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A et al. (2012)
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 8 (4), 445-544
DOI 10.4161/auto.19496, PubMed 22966490
Lobert VH, Bruun J, Abrahamsen H, Lothe RA, Stenmark H, Kolberg M, Campsteijn C (2012)
Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin
EMBO Rep, 14 (1), 10-1
DOI 10.1038/embor.2012.188, PubMed 23229585
Lobert VH, Stenmark H (2012)
The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain
J Cell Sci, 125 (Pt 1), 29-36
DOI 10.1242/jcs.088310, PubMed 22266905
Nezis IP (2012)
Selective autophagy in Drosophila
Int J Cell Biol, 2012, 146767
DOI 10.1155/2012/146767, PubMed 22567011
Nezis IP, Stenmark H (2012)
p62 at the interface of autophagy, oxidative stress signaling, and cancer
Antioxid Redox Signal, 17 (5), 786-93
DOI 10.1089/ars.2011.4394, PubMed 22074114
Oksvold MP, Pedersen NM, Forfang L, Smeland EB (2012)
Effect of cycloheximide on epidermal growth factor receptor trafficking and signaling
FEBS Lett, 586 (20), 3575-81
DOI 10.1016/j.febslet.2012.08.022, PubMed 22971756
Oppelt A, Lobert VH, Haglund K, Mackey AM, Rameh LE, Liestøl K, Schink KO, Pedersen NM, Wenzel EM, Haugsten EM, Brech A, Rusten TE, Stenmark H, Wesche J (2012)
Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration
EMBO Rep, 14 (1), 57-64
DOI 10.1038/embor.2012.183, PubMed 23154468
Pedersen NM, Raiborg C, Brech A, Skarpen E, Roxrud I, Platta HW, Liestøl K, Stenmark H (2012)
The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion
Traffic, 13 (11), 1547-63
DOI 10.1111/j.1600-0854.2012.01400.x, PubMed 22816767
Platta HW, Abrahamsen H, Thoresen SB, Stenmark H (2012)
Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1
Biochem J, 441 (1), 399-406
DOI 10.1042/BJ20111424, PubMed 21936852
Sak MM, Breen K, Rønning SB, Pedersen NM, Bertelsen V, Stang E, Madshus IH (2012)
The oncoprotein ErbB3 is endocytosed in the absence of added ligand in a clathrin-dependent manner
Carcinogenesis, 33 (5), 1031-9
DOI 10.1093/carcin/bgs128, PubMed 22436610
Szlachcic A, Pala K, Zakrzewska M, Jakimowicz P, Wiedlocha A, Otlewski J (2012)
FGF1-gold nanoparticle conjugates targeting FGFR efficiently decrease cell viability upon NIR irradiation
Int J Nanomedicine, 7, 5915-27
DOI 10.2147/IJN.S36575, PubMed 23226697
Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S (2012)
A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice
Cancer Res, 72 (11), 2822-32
DOI 10.1158/0008-5472.CAN-11-3336, PubMed 22440753
Zhen Y, Sørensen V, Skjerpen CS, Haugsten EM, Jin Y, Wälchli S, Olsnes S, Wiedlocha A (2012)
Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnα1 and Kpnβ1
Traffic, 13 (5), 650-64
DOI 10.1111/j.1600-0854.2012.01341.x, PubMed 22321063

Publications 2011

Abrahamsen H, Stenmark H (2011)
Cell biology. Growth signaling from inside
Science, 334 (6056), 611-2
DOI 10.1126/science.1214355, PubMed 22053037
Bartlett BJ, Isakson P, Lewerenz J, Sanchez H, Kotzebue RW, Cumming RC, Harris GL, Nezis IP, Schubert DR, Simonsen A, Finley KD (2011)
p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects
Autophagy, 7 (6), 572-83
DOI 10.4161/auto.7.6.14943, PubMed 21325881
Freitag J, Lanver D, Böhmer C, Schink KO, Bölker M, Sandrock B (2011)
Septation of infectious hyphae is critical for appressoria formation and virulence in the smut fungus Ustilago maydis
PLoS Pathog, 7 (5), e1002044
DOI 10.1371/journal.ppat.1002044, PubMed 21625538
Grimm I, Saffian D, Platta HW, Erdmann R (2011)
The AAA-type ATPases Pex1p and Pex6p and their role in peroxisomal matrix protein import in Saccharomyces cerevisiae
Biochim Biophys Acta, 1823 (1), 150-8
DOI 10.1016/j.bbamcr.2011.09.005, PubMed 21963882
Grunau S, Lay D, Mindthoff S, Platta HW, Girzalsky W, Just WW, Erdmann R (2011)
The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae
Biochem J, 434 (1), 161-70
DOI 10.1042/BJ20101115, PubMed 21121900
Haglund K, Nezis IP, Stenmark H (2011)
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
Commun Integr Biol, 4 (1), 1-9
DOI 10.4161/cib.4.1.13550, PubMed 21509167
Haugsten EM, Zakrzewska M, Brech A, Pust S, Olsnes S, Sandvig K, Wesche J (2011)
Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling
PLoS One, 6 (7), e21708
DOI 10.1371/journal.pone.0021708, PubMed 21779335
Helmrich U, Marsano A, Melly L, Wolff T, Christ L, Heberer M, Scherberich A, Martin I, Banfi A (2011)
Generation of human adult mesenchymal stromal/stem cells expressing defined xenogenic vascular endothelial growth factor levels by optimized transduction and flow cytometry purification
Tissue Eng Part C Methods, 18 (4), 283-92
DOI 10.1089/ten.TEC.2011.0413, PubMed 22070632
Hurley JH, Stenmark H (2011)
Molecular mechanisms of ubiquitin-dependent membrane traffic
Annu Rev Biophys, 40, 119-42
DOI 10.1146/annurev-biophys-042910-155404, PubMed 21332354
Jin Y, Zhen Y, Haugsten EM, Wiedlocha A (2011)
The driver of malignancy in KG-1a leukemic cells, FGFR1OP2-FGFR1, encodes an HSP90 addicted oncoprotein
Cell Signal, 23 (11), 1758-66
DOI 10.1016/j.cellsig.2011.06.010, PubMed 21745565
Lind GE, Raiborg C, Danielsen SA, Rognum TO, Thiis-Evensen E, Hoff G, Nesbakken A, Stenmark H, Lothe RA (2011)
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
Oncogene, 30 (37), 3967-78
DOI 10.1038/onc.2011.109, PubMed 21499309
Lobert VH, Stenmark H (2011)
Cell polarity and migration: emerging role for the endosomal sorting machinery
Physiology (Bethesda), 26 (3), 171-80
DOI 10.1152/physiol.00054.2010, PubMed 21670163
Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
Traffic, 12 (9), 1211-26
DOI 10.1111/j.1600-0854.2011.01220.x, PubMed 21564451
Martinez AL, Roxrud I (2011)
Basic and discovery-based translational research on cancer was on the agenda at the 21st Congress of the European Association for Cancer Research (EACR) in Oslo, Norway, 26-29 June 2010
Clin. Transl. Oncol., 13 (1), 1-2
DOI 10.1007/s12094-011-0608-y
Moosmann A, Campsteijn C, Jansen PW, Nasrallah C, Raasholm M, Stunnenberg HG, Thompson EM (2011)
Histone variant innovation in a rapidly evolving chordate lineage
BMC Evol Biol, 11, 208
DOI 10.1186/1471-2148-11-208, PubMed 21756361
Platta HW, Stenmark H (2011)
Endocytosis and signaling
Curr Opin Cell Biol, 23 (4), 393-403
DOI 10.1016/j.ceb.2011.03.008, PubMed 21474295
Raiborg C, Stenmark H (2011)
Cell biology. A helix for the final cut
Science, 331 (6024), 1533-4
DOI 10.1126/science.1204208, PubMed 21436431
Rusten TE, Vaccari T, Stenmark H (2011)
Shaping development with ESCRTs
Nat Cell Biol, 14 (1), 38-45
DOI 10.1038/ncb2381, PubMed 22193162
Rønning SB, Pedersen NM, Madshus IH, Stang E (2011)
CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor
Exp Cell Res, 317 (13), 1804-16
DOI 10.1016/j.yexcr.2011.05.016, PubMed 21635887
Sagona AP, Nezis IP, Bache KG, Haglund K, Bakken AC, Skotheim RI, Stenmark H (2011)
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
PLoS One, 6 (3), e17086
DOI 10.1371/journal.pone.0017086, PubMed 21455500
Schink KO, Stenmark H (2011)
Cell differentiation: midbody remnants - junk or fate factors?
Curr Biol, 21 (23), R958-60
DOI 10.1016/j.cub.2011.10.035, PubMed 22153165
Shahzidi S, Cunderlíková B, Więdłocha A, Zhen Y, Vasovič V, Nesland JM, Peng Q (2011)
Simultaneously targeting mitochondria and endoplasmic reticulum by photodynamic therapy induces apoptosis in human lymphoma cells
Photochem Photobiol Sci, 10 (11), 1773-82
DOI 10.1039/c1pp05169e, PubMed 21881674
Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E (2011)
Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
Int J Cancer, 131 (3), 570-81
DOI 10.1002/ijc.26392, PubMed 21866551
Stenmark H (2011)
Harald Stenmark: hands on FYVE-fingers. Interview by Caitlin Sedwick
J Cell Biol, 192 (4), 544-5
DOI 10.1083/jcb.1924pi, PubMed 21339328
Takahashi Y, Shimokawa N, Esmaeili-Mahani S, Morita A, Masuda H, Iwasaki T, Tamura J, Haglund K, Koibuchi N (2011)
Ligand-induced downregulation of TrkA is partly regulated through ubiquitination by Cbl
FEBS Lett, 585 (12), 1741-7
DOI 10.1016/j.febslet.2011.04.056, PubMed 21570973
Ugland H, Naderi S, Brech A, Collas P, Blomhoff HK (2011)
cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1
Autophagy, 7 (10), 1199-211
DOI 10.4161/auto.7.10.16649, PubMed 21750416
Warsame AA, Aasheim HC, Nustad K, Trøen G, Tierens A, Wang V, Randen U, Dong HP, Heim S, Brech A, Delabie J (2011)
Splenic marginal zone lymphoma with VH1-02 gene rearrangement expresses poly- and self-reactive antibodies with similar reactivity
Blood, 118 (12), 3331-9
DOI 10.1182/blood-2011-03-341651, PubMed 21725051
Wegner CS, Rodahl LM, Stenmark H (2011)
ESCRT proteins and cell signalling
Traffic, 12 (10), 1291-7
DOI 10.1111/j.1600-0854.2011.01210.x, PubMed 21518165
Wesche J, Haglund K, Haugsten EM (2011)
Fibroblast growth factors and their receptors in cancer
Biochem J, 437 (2), 199-213
DOI 10.1042/BJ20101603, PubMed 21711248
Zakrzewska M, Sørensen V, Jin Y, Wiedlocha A, Olsnes S (2011)
Translocation of exogenous FGF1 into cytosol and nucleus is a periodic event independent of receptor kinase activity
Exp Cell Res, 317 (7), 1005-15
DOI 10.1016/j.yexcr.2011.01.003, PubMed 21223966

Publications 2010

Abrahamsen H, Stenmark H (2010)
Protein secretion: unconventional exit by exophagy
Curr Biol, 20 (9), R415-8
DOI 10.1016/j.cub.2010.03.011, PubMed 20462486
Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T (2010)
p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
Autophagy, 6 (3), 330-44
DOI 10.4161/auto.6.3.11226, PubMed 20168092
Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A (2010)
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
Mol Cell, 38 (2), 265-79
DOI 10.1016/j.molcel.2010.04.007, PubMed 20417604
Groves B, Abrahamsen H, Clingan H, Frantz M, Mavor L, Bailey J, Ma D (2010)
An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy
PLoS One, 5 (1), e8877
DOI 10.1371/journal.pone.0008877, PubMed 20126274
Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestøl K, Dikic I, Palmer R, Stenmark H (2010)
Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
Curr Biol, 20 (10), 944-50
DOI 10.1016/j.cub.2010.03.068, PubMed 20451383
Halaas O, Steigedal M, Haug M, Awuh JA, Ryan L, Brech A, Sato S, Husebye H, Cangelosi GA, Akira S, Strong RK, Espevik T, Flo TH (2010)
Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathway
J Infect Dis, 201 (5), 783-92
DOI 10.1086/650493, PubMed 20121435
Haugsten EM, Wiedlocha A, Olsnes S, Wesche J (2010)
Roles of fibroblast growth factor receptors in carcinogenesis
Mol Cancer Res, 8 (11), 1439-52
DOI 10.1158/1541-7786.MCR-10-0168, PubMed 21047773
Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, Nilsen NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T (2010)
The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
Immunity, 33 (4), 583-96
DOI 10.1016/j.immuni.2010.09.010, PubMed 20933442
Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
Autophagy, 6 (7), 863-70
DOI 10.4161/auto.6.7.13033, PubMed 20724836
Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L, Stenmark H (2010)
Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes
Dev Cell, 19 (1), 148-59
DOI 10.1016/j.devcel.2010.06.010, PubMed 20643357
Lobert VH, Stenmark H (2010)
Ubiquitination of α-integrin cytoplasmic tails
Commun Integr Biol, 3 (6), 583-5
DOI 10.4161/cib.3.6.13176, PubMed 21331246
Malagoli D, Abdalla FC, Cao Y, Feng Q, Fujisaki K, Gregorc A, Matsuo T, Nezis IP, Papassideri IS, Sass M, Silva-Zacarin EC, Tettamanti G, Umemiya-Shirafuji R (2010)
Autophagy and its physiological relevance in arthropods: current knowledge and perspectives
Autophagy, 6 (5), 575-88
DOI 10.4161/auto.6.5.11962, PubMed 20458176
Nezis IP, Sagona AP, Schink KO, Stenmark H (2010)
Divide and ProsPer: the emerging role of PtdIns3P in cytokinesis
Trends Cell Biol, 20 (11), 642-9
DOI 10.1016/j.tcb.2010.08.010, PubMed 20880709
Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
Autophagy as a trigger for cell death Autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-+
DOI 10.4161/auto.6.8.13694
Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
Autophagy as a trigger for cell death: autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-5
DOI 10.4161/auto.6.8.13694, PubMed 20935512
Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjørkøy G, Johansen T, Rusten TE, Brech A, Baehrecke EH, Stenmark H (2010)
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
J Cell Biol, 190 (4), 523-31
DOI 10.1083/jcb.201002035, PubMed 20713604
Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A, Bjørkøy G, Johansen T (2010)
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
J Cell Biol, 188 (2), 253-69
DOI 10.1083/jcb.200907015, PubMed 20100911
Roxrud I, Stenmark H, Malerød L (2010)
ESCRT & Co
Biol Cell, 102 (5), 293-318
DOI 10.1042/BC20090161, PubMed 20222872
Rusten TE, Stenmark H (2010)
p62, an autophagy hero or culprit?
Nat Cell Biol, 12 (3), 207-9
DOI 10.1038/ncb0310-207, PubMed 20190829
Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
DOI 10.1038/ncb2036, PubMed 20208530
Sagona AP, Stenmark H (2010)
Cytokinesis and cancer (vol 584, pg 2652, 2010)
FEBS Lett., 584 (18), 4128
DOI 10.1016/j.febslet.2010.08.016
Sagona AP, Stenmark H (2010)
Cytokinesis and cancer
FEBS Lett, 584 (12), 2652-61
DOI 10.1016/j.febslet.2010.03.044, PubMed 20371245
Shimokawa N, Haglund K, Hölter SM, Grabbe C, Kirkin V, Koibuchi N, Schultz C, Rozman J, Hoeller D, Qiu CH, Londoño MB, Ikezawa J, Jedlicka P, Stein B, Schwarzacher SW, Wolfer DP, Ehrhardt N, Heuchel R, Nezis I, Brech A, Schmidt MHH, Fuchs H, Gailus-Durner V, Klingenspor M, Bogler O et al. (2010)
CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice
EMBO J, 29 (14), 2421-32
DOI 10.1038/emboj.2010.120, PubMed 20551902
Stuffers S, Malerød L, Schink KO, Corvera S, Stenmark H, Brech A (2010)
Time-resolved ultrastructural detection of phosphatidylinositol 3-phosphate
J Histochem Cytochem, 58 (11), 1025-32
DOI 10.1369/jhc.2010.955815, PubMed 20713985
Teichmann B, Liu L, Schink KO, Bölker M (2010)
Activation of the ustilagic acid biosynthesis gene cluster in Ustilago maydis by the C2H2 zinc finger transcription factor Rua1
Appl Environ Microbiol, 76 (8), 2633-40
DOI 10.1128/AEM.02211-09, PubMed 20173069
Thoresen SB, Pedersen NM, Liestøl K, Stenmark H (2010)
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
Exp Cell Res, 316 (20), 3368-78
DOI 10.1016/j.yexcr.2010.07.008, PubMed 20643123

Publications 2009

Bjørkøy G, Lamark T, Pankiv S, Øvervatn A, Brech A, Johansen T (2009)
Monitoring autophagic degradation of p62/SQSTM1
Methods Enzymol, 452, 181-97
DOI 10.1016/S0076-6879(08)03612-4, PubMed 19200883
Brech A, Ahlquist T, Lothe RA, Stenmark H (2009)
Autophagy in tumour suppression and promotion
Mol Oncol, 3 (4), 366-75
DOI 10.1016/j.molonc.2009.05.007, PubMed 19559660
Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
J Cell Sci, 122 (Pt 21), 3883-93
DOI 10.1242/jcs.053801, PubMed 19808888
Malerød L, Stenmark H (2009)
ESCRTing membrane deformation
Cell, 136 (1), 15-7
DOI 10.1016/j.cell.2008.12.029, PubMed 19135881
Nezis IP, Lamark T, Velentzas AD, Rusten TE, Bjørkøy G, Johansen T, Papassideri IS, Stravopodis DJ, Margaritis LH, Stenmark H, Brech A (2009)
Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
Autophagy, 5 (3), 298-302
DOI 10.4161/auto.5.3.7454, PubMed 19066465
Raiborg C, Stenmark H (2009)
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
Nature, 458 (7237), 445-52
DOI 10.1038/nature07961, PubMed 19325624
Rodahl LM, Haglund K, Sem-Jacobsen C, Wendler F, Vincent JP, Lindmo K, Rusten TE, Stenmark H (2009)
Disruption of Vps4 and JNK function in Drosophila causes tumour growth
PLoS One, 4 (2), e4354
DOI 10.1371/journal.pone.0004354, PubMed 19194501
Rodahl LM, Stuffers S, Lobert VH, Stenmark H (2009)
The role of ESCRT proteins in attenuation of cell signalling
Biochem Soc Trans, 37 (Pt 1), 137-42
DOI 10.1042/BST0370137, PubMed 19143618
Roxrud I, Raiborg C, Gilfillan GD, Strømme P, Stenmark H (2009)
Dual degradation mechanisms ensure disposal of NHE6 mutant protein associated with neurological disease
Exp Cell Res, 315 (17), 3014-27
DOI 10.1016/j.yexcr.2009.07.012, PubMed 19619532
Rusten TE, Stenmark H (2009)
How do ESCRT proteins control autophagy?
J Cell Sci, 122 (Pt 13), 2179-83
DOI 10.1242/jcs.050021, PubMed 19535733
Skånland SS, Wälchli S, Brech A, Sandvig K (2009)
SNX4 in complex with clathrin and dynein: implications for endosome movement
PLoS One, 4 (6), e5935
DOI 10.1371/journal.pone.0005935, PubMed 19529763
Stenmark H (2009)
Rab GTPases as coordinators of vesicle traffic
Nat Rev Mol Cell Biol, 10 (8), 513-25
DOI 10.1038/nrm2728, PubMed 19603039
Stenmark H (2009)
Seeing is believing
Nat Rev Mol Cell Biol, 10 (9), 582
DOI 10.1038/nrm2747, PubMed 19702012
Stuffers S, Sem Wegner C, Stenmark H, Brech A (2009)
Multivesicular endosome biogenesis in the absence of ESCRTs
Traffic, 10 (7), 925-37
DOI 10.1111/j.1600-0854.2009.00920.x, PubMed 19490536
Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D (2009)
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
J Cell Sci, 122 (Pt 14), 2413-23
DOI 10.1242/jcs.046391, PubMed 19571114
Wegner CS, Malerød L, Pedersen NM, Progida C, Bakke O, Stenmark H, Brech A (2009)
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
Histochem Cell Biol, 133 (1), 41-55
DOI 10.1007/s00418-009-0643-8, PubMed 19830447
Zakrzewska M, Wiedlocha A, Szlachcic A, Krowarsch D, Otlewski J, Olsnes S (2009)
Increased protein stability of FGF1 can compensate for its reduced affinity for heparin
J Biol Chem, 284 (37), 25388-403
DOI 10.1074/jbc.M109.001289, PubMed 19574212
Zakrzewska M, Zhen Y, Wiedlocha A, Olsnes S, Wesche J (2009)
Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane
Biochemistry, 48 (30), 7209-18
DOI 10.1021/bi9007353, PubMed 19558187
Zheng YT, Shahnazari S, Brech A, Lamark T, Johansen T, Brumell JH (2009)
The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway
J Immunol, 183 (9), 5909-16
DOI 10.4049/jimmunol.0900441, PubMed 19812211

Publications 2008

Bergeland T, Haugen L, Landsverk OJ, Stenmark H, Bakke O (2008)
Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1
EMBO Rep, 9 (2), 171-8
DOI 10.1038/sj.embor.7401152, PubMed 18188183
Cumming RC, Simonsen A, Finley KD (2008)
Quantitative analysis of autophagic activity in Drosophila neural tissues by measuring the turnover rates of pathway substrates
Methods Enzymol, 451, 639-51
DOI 10.1016/S0076-6879(08)03235-7, PubMed 19185743
Gilfillan GD, Selmer KK, Roxrud I, Smith R, Kyllerman M, Eiklid K, Kroken M, Mattingsdal M, Egeland T, Stenmark H, Sjøholm H, Server A, Samuelsson L, Christianson A, Tarpey P, Whibley A, Stratton MR, Futreal PA, Teague J, Edkins S, Gecz J, Turner G, Raymond FL, Schwartz C, Stevenson RE et al. (2008)
SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome
Am J Hum Genet, 82 (4), 1003-10
DOI 10.1016/j.ajhg.2008.01.013, PubMed 18342287
Grosso S, Volta V, Sala LA, Vietri M, Marchisio PC, Ron D, Biffo S (2008)
PKCbetaII modulates translation independently from mTOR and through RACK1
Biochem J, 415 (1), 77-85
DOI 10.1042/BJ20080463, PubMed 18557705
Grosso S, Volta V, Vietri M, Gorrini C, Marchisio PC, Biffo S (2008)
Eukaryotic ribosomes host PKC activity
Biochem Biophys Res Commun, 376 (1), 65-9
DOI 10.1016/j.bbrc.2008.08.118, PubMed 18768137
Haugsten EM, Malecki J, Bjørklund SM, Olsnes S, Wesche J (2008)
Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis
Mol Biol Cell, 19 (8), 3390-403
DOI 10.1091/mbc.e07-12-1219, PubMed 18480409
Lindmo K, Brech A, Finley KD, Gaumer S, Contamine D, Rusten TE, Stenmark H (2008)
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
Autophagy, 4 (4), 500-6
DOI 10.4161/auto.5829, PubMed 18326940
Miaczynska M, Stenmark H (2008)
Mechanisms and functions of endocytosis
J Cell Biol, 180 (1), 7-11
DOI 10.1083/jcb.200711073, PubMed 18195098
Morrison HA, Dionne H, Rusten TE, Brech A, Fisher WW, Pfeiffer BD, Celniker SE, Stenmark H, Bilder D (2008)
Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45
Mol Biol Cell, 19 (10), 4167-76
DOI 10.1091/mbc.e08-07-0716, PubMed 18685079
Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A (2008)
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
J Cell Biol, 180 (6), 1065-71
DOI 10.1083/jcb.200711108, PubMed 18347073
Raposo G, Stenmark H (2008)
Membranes and organelles
Curr Opin Cell Biol, 20 (4), 357-9
DOI 10.1016/j.ceb.2008.06.005, PubMed 18588977
Rusten TE, Filimonenko M, Rodahl LM, Stenmark H, Simonsen A (2008)
ESCRTing autophagic clearance of aggregating proteins
Autophagy, 4 (2), 233-236
DOI 10.4161/auto.5396
Rusten TE, Simonsen A (2008)
ESCRT functions in autophagy and associated disease
Cell Cycle, 7 (9), 1166-72
DOI 10.4161/cc.7.9.5784, PubMed 18418046
Stuffers S, Brech A, Stenmark H (2008)
ESCRT proteins in physiology and disease
Exp Cell Res, 315 (9), 1619-26
DOI 10.1016/j.yexcr.2008.10.013, PubMed 19013455
Sørensen V, Zhen Y, Zakrzewska M, Haugsten EM, Wälchli S, Nilsen T, Olsnes S, Wiedlocha A (2008)
Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus
Mol Cell Biol, 28 (12), 4129-41
DOI 10.1128/MCB.02117-07, PubMed 18411303
Umebayashi K, Stenmark H, Yoshimori T (2008)
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
Mol Biol Cell, 19 (8), 3454-62
DOI 10.1091/mbc.e07-10-0988, PubMed 18508924
Zakrzewska M, Marcinkowska E, Wiedlocha A (2008)
FGF-1: from biology through engineering to potential medical applications
Crit Rev Clin Lab Sci, 45 (1), 91-135
DOI 10.1080/10408360701713120, PubMed 18293181

Publications 2007

Citores L, Bai L, Sørensen V, Olsnes S (2007)
Fibroblast growth factor receptor-induced phosphorylation of STAT1 at the Golgi apparatus without translocation to the nucleus
J Cell Physiol, 212 (1), 148-56
DOI 10.1002/jcp.21014, PubMed 17311277
Feugaing DD, Tammi R, Echtermeyer FG, Stenmark H, Kresse H, Smollich M, Schönherr E, Kiesel L, Götte M (2007)
Endocytosis of the dermatan sulfate proteoglycan decorin utilizes multiple pathways and is modulated by epidermal growth factor receptor signaling
Biochimie, 89 (5), 637-57
DOI 10.1016/j.biochi.2006.12.012, PubMed 17335953
Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A (2007)
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
J Cell Biol, 179 (3), 485-500
DOI 10.1083/jcb.200702115, PubMed 17984323
Haglund K, Rusten TE, Stenmark H (2007)
Aberrant receptor signaling and trafficking as mechanisms in oncogenesis
Crit Rev Oncog, 13 (1), 39-74
DOI 10.1615/critrevoncog.v13.i1.20, PubMed 17956217
Hughes T, Rusten TE (2007)
Origin and evolution of self-consumption: autophagy
Adv Exp Med Biol, 607, 111-8
DOI 10.1007/978-0-387-74021-8_9, PubMed 17977463
Kurmanova A, Llorente A, Polesskaya A, Garred O, Olsnes S, Kozlov J, Sandvig K (2007)
Structural requirements for furin-induced cleavage and activation of Shiga toxin
Biochem Biophys Res Commun, 357 (1), 144-9
DOI 10.1016/j.bbrc.2007.03.110, PubMed 17407762
Malerød L, Stenmark H (2007)
ESCRTs
Curr Biol, 17 (2), R42-3
DOI 10.1016/j.cub.2006.12.009, PubMed 17240322
Malerød L, Stuffers S, Brech A, Stenmark H (2007)
Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation
Traffic, 8 (11), 1617-29
DOI 10.1111/j.1600-0854.2007.00630.x, PubMed 17714434
Nilsen T, Rosendal KR, Sørensen V, Wesche J, Olsnes S, Wiedłocha A (2007)
A nuclear export sequence located on a beta-strand in fibroblast growth factor-1
J Biol Chem, 282 (36), 26245-56
DOI 10.1074/jbc.M611234200, PubMed 17616529
Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T (2007)
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
J Biol Chem, 282 (33), 24131-45
DOI 10.1074/jbc.M702824200, PubMed 17580304
Progida C, Malerød L, Stuffers S, Brech A, Bucci C, Stenmark H (2007)
RILP is required for the proper morphology and function of late endosomes
J Cell Sci, 120 (Pt 21), 3729-37
DOI 10.1242/jcs.017301, PubMed 17959629
Raiborg C, Malerød L, Pedersen NM, Stenmark H (2007)
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
Exp Cell Res, 314 (4), 801-13
DOI 10.1016/j.yexcr.2007.10.014, PubMed 18031739
Rusten TE, Stenmark H (2007)
Developmental biology: moonlighting at the pole
Nature, 445 (7127), 497-9
DOI 10.1038/445497a, PubMed 17268460
Rusten TE, Vaccari T, Lindmo K, Rodahl LM, Nezis IP, Sem-Jacobsen C, Wendler F, Vincent JP, Brech A, Bilder D, Stenmark H (2007)
ESCRTs and Fab1 regulate distinct steps of autophagy
Curr Biol, 17 (20), 1817-25
DOI 10.1016/j.cub.2007.09.032, PubMed 17935992
Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD (2007)
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
Autophagy, 4 (2), 176-84
DOI 10.4161/auto.5269, PubMed 18059160
Simonsen A, Cumming RC, Lindmo K, Galaviz V, Cheng S, Rusten TE, Finley KD (2007)
Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles
Genetics, 176 (2), 1283-97
DOI 10.1534/genetics.106.065011, PubMed 17435236
Simonsen A, Stenmark H (2007)
Stimulating the cell's appetite for itself
Nat Chem Biol, 3 (6), 304-6
DOI 10.1038/nchembio0607-304, PubMed 17510644
Zhen Y, Sørensen V, Jin Y, Suo Z, Wiedłocha A (2007)
Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
Oncogene, 26 (44), 6372-85
DOI 10.1038/sj.onc.1210473, PubMed 17533378

Publications 2006

Bache KG (2006)
The function of ubiquitin-binding protein complexes in endocytic downregulation of growth factor receptors
Crit Rev Oncog, 12 (3-4), 301; discussion 301-2
DOI 10.1615/critrevoncog.v12.i3-4.90, PubMed 17425510
Bache KG, Stuffers S, Malerød L, Slagsvold T, Raiborg C, Lechardeur D, Wälchli S, Lukacs GL, Brech A, Stenmark H (2006)
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
Mol Biol Cell, 17 (6), 2513-23
DOI 10.1091/mbc.e05-10-0915, PubMed 16554368
Cabezas A, Pattni K, Stenmark H (2006)
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
Gene, 371 (1), 34-41
DOI 10.1016/j.gene.2005.11.009, PubMed 16448788
Haglund K, Stenmark H (2006)
Working out coupled monoubiquitination
Nat Cell Biol, 8 (11), 1218-9
DOI 10.1038/ncb1106-1218, PubMed 17077855
Hecker CM, Rabiller M, Haglund K, Bayer P, Dikic I (2006)
Specification of SUMO1- and SUMO2-interacting motifs
J Biol Chem, 281 (23), 16117-27
DOI 10.1074/jbc.M512757200, PubMed 16524884
Hirano S, Kawasaki M, Ura H, Kato R, Raiborg C, Stenmark H, Wakatsuki S (2006)
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Nat Struct Mol Biol, 13 (3), 272-7
DOI 10.1038/nsmb1051, PubMed 16462748
Hirano S, Suzuki N, Slagsvold T, Kawasaki M, Trambaiolo D, Kato R, Stenmark H, Wakatsuki S (2006)
Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain
Nat Struct Mol Biol, 13 (11), 1031-2
DOI 10.1038/nsmb1163, PubMed 17057714
Hoeller D, Crosetto N, Blagoev B, Raiborg C, Tikkanen R, Wagner S, Kowanetz K, Breitling R, Mann M, Stenmark H, Dikic I (2006)
Regulation of ubiquitin-binding proteins by monoubiquitination
Nat Cell Biol, 8 (2), 163-9
DOI 10.1038/ncb1354, PubMed 16429130
Husebye H, Halaas Ø, Stenmark H, Tunheim G, Sandanger Ø, Bogen B, Brech A, Latz E, Espevik T (2006)
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
EMBO J, 25 (4), 683-92
DOI 10.1038/sj.emboj.7600991, PubMed 16467847
Johannessen LE, Pedersen NM, Pedersen KW, Madshus IH, Stang E (2006)
Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits
Mol Cell Biol, 26 (2), 389-401
DOI 10.1128/MCB.26.2.389-401.2006, PubMed 16382132
Kazazic M, Roepstorff K, Johannessen LE, Pedersen NM, van Deurs B, Stang E, Madshus IH (2006)
EGF-induced activation of the EGF receptor does not trigger mobilization of caveolae
Traffic, 7 (11), 1518-27
DOI 10.1111/j.1600-0854.2006.00487.x, PubMed 16984407
Khnykin D, Olsnes S (2006)
Reduced binding of FGF1 to mutant fibroblast growth factor receptor 3
Growth Factors, 24 (2), 111-9
DOI 10.1080/08977190600621388, PubMed 16801131
Klokk TI, Kurys P, Elbi C, Nagaich AK, Hendarwanto A, Slagsvold T, Chang CY, Hager GL, Saatcioglu F (2006)
Ligand-specific dynamics of the androgen receptor at its response element in living cells
Mol Cell Biol, 27 (5), 1823-43
DOI 10.1128/MCB.01297-06, PubMed 17189428
Leithe E, Brech A, Rivedal E (2006)
Endocytic processing of connexin43 gap junctions: a morphological study
Biochem J, 393 (Pt 1), 59-67
DOI 10.1042/BJ20050674, PubMed 16162097
Lindmo K, Simonsen A, Brech A, Finley K, Rusten TE, Stenmark H (2006)
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
Exp Cell Res, 312 (11), 2018-27
DOI 10.1016/j.yexcr.2006.03.002, PubMed 16600212
Lindmo K, Stenmark H (2006)
Regulation of membrane traffic by phosphoinositide 3-kinases
J Cell Sci, 119 (Pt 4), 605-14
DOI 10.1242/jcs.02855, PubMed 16467569
Lindmo K, Stenmark H (2006)
How a RING finger protein and a steroid hormone control autophagy
Autophagy, 2 (4), 321-2
DOI 10.4161/auto.3091, PubMed 16874068
Marcinkowska E, Superat K, Wiedłocha A (2006)
FGF-1 as a possible carrier for targeted drug delivery
Oncol Res, 16 (1), 27-34
DOI 10.3727/000000006783981242, PubMed 16783965
Myromslien FD, Grøvdal LM, Raiborg C, Stenmark H, Madshus IH, Stang E (2006)
Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
Exp Cell Res, 312 (16), 3036-48
DOI 10.1016/j.yexcr.2006.06.004, PubMed 16859684
Norlén L, Gil IP, Simonsen A, Descouts P (2006)
Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films
J Struct Biol, 158 (3), 386-400
DOI 10.1016/j.jsb.2006.12.006, PubMed 17287132
Raiborg C (2006)
Hrs makes receptors silent: a key to endosomal protein sorting
Crit Rev Oncog, 12 (3-4), 295, discussion 295-6
DOI 10.1615/critrevoncog.v12.i3-4.70, PubMed 17425508
Raiborg C, Slagsvold T, Stenmark H (2006)
A new side to ubiquitin
Trends Biochem Sci, 31 (10), 541-4
DOI 10.1016/j.tibs.2006.07.009, PubMed 16901703
Raiborg C, Wesche J, Malerød L, Stenmark H (2006)
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
J Cell Sci, 119 (Pt 12), 2414-24
DOI 10.1242/jcs.02978, PubMed 16720641
Rusten TE, Rodahl LM, Pattni K, Englund C, Samakovlis C, Dove S, Brech A, Stenmark H (2006)
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
Mol Biol Cell, 17 (9), 3989-4001
DOI 10.1091/mbc.e06-03-0239, PubMed 16837550
Rusten TE, Stenmark H (2006)
Analyzing phosphoinositides and their interacting proteins
Nat Methods, 3 (4), 251-8
DOI 10.1038/nmeth867, PubMed 16554828
Rutherford AC, Traer C, Wassmer T, Pattni K, Bujny MV, Carlton JG, Stenmark H, Cullen PJ (2006)
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
J Cell Sci, 119 (Pt 19), 3944-57
DOI 10.1242/jcs.03153, PubMed 16954148
Slagsvold T, Marchese A, Brech A, Stenmark H (2006)
CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
EMBO J, 25 (16), 3738-49
DOI 10.1038/sj.emboj.7601267, PubMed 16888620
Slagsvold T, Pattni K, Malerød L, Stenmark H (2006)
Endosomal and non-endosomal functions of ESCRT proteins
Trends Cell Biol, 16 (6), 317-26
DOI 10.1016/j.tcb.2006.04.004, PubMed 16716591
Sørensen V, Nilsen T, Wiedłocha A (2006)
Functional diversity of FGF-2 isoforms by intracellular sorting
Bioessays, 28 (5), 504-14
DOI 10.1002/bies.20405, PubMed 16615083
Sørensen V, Wiedlocha A, Haugsten EM, Khnykin D, Wesche J, Olsnes S (2006)
Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail
J Cell Sci, 119 (Pt 20), 4332-41
DOI 10.1242/jcs.03209, PubMed 17003104
Wesche J, Małecki J, Wiedłocha A, Skjerpen CS, Claus P, Olsnes S (2006)
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus
J Biol Chem, 281 (16), 11405-12
DOI 10.1074/jbc.M600477200, PubMed 16495214
Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2006)
Structural requirements of FGF-1 for receptor binding and translocation into cells
Biochemistry, 45 (51), 15338-48
DOI 10.1021/bi0618114, PubMed 17176056

Publications 2005

Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T (2005)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
J Cell Biol, 171 (4), 603-14
DOI 10.1083/jcb.200507002, PubMed 16286508
Cabezas A, Bache KG, Brech A, Stenmark H (2005)
Alix regulates cortical actin and the spatial distribution of endosomes
J Cell Sci, 118 (Pt 12), 2625-35
DOI 10.1242/jcs.02382, PubMed 15914539
Canales J, Cabezas A, Pinto RM, Cameselle JC (2005)
Fluorimetric HPLC detection of endogenous riboflavin 4',5'-cyclic phosphate in rat liver at nanomolar concentrations
Anal Biochem, 341 (2), 214-9
DOI 10.1016/j.ab.2005.01.060, PubMed 15907866
Drevon T, Slagsvold T (2005)
When and from whom do female pied flycatchers (Ficedula hypoleuca) solicit copulations
Behaviour, 142, 1059-1076
DOI 10.1163/156853905774405335
Haugsten EM, Sørensen V, Brech A, Olsnes S, Wesche J (2005)
Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors
J Cell Sci, 118 (Pt 17), 3869-81
DOI 10.1242/jcs.02509, PubMed 16091423
Hoepfner S, Severin F, Cabezas A, Habermann B, Runge A, Gillooly D, Stenmark H, Zerial M (2005)
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B
Cell, 121 (3), 437-50
DOI 10.1016/j.cell.2005.02.017, PubMed 15882625
Høiseth G, Olsnes S (2005)
[Ricin--a therapeutic agent and a biological weapon]
Tidsskr Nor Laegeforen, 125 (18), 2477-9
PubMed 16186864
Johannessen LE, Slagsvold T, Hansen BT, Lifjeld JT (2005)
Manipulation of male quality in wild tits: effects on paternity loss
Behav. Ecol., 16 (4), 747-754
DOI 10.1093/beheco/ari048
Korobko E, Kiselev S, Olsnes S, Stenmark H, Korobko I (2005)
The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5delta differ in their ability to interact with the small GTPase Rab4
FEBS J, 272 (1), 37-46
DOI 10.1111/j.1742-4658.2004.04387.x, PubMed 15634330
Longva KE, Pedersen NM, Haslekås C, Stang E, Madshus IH (2005)
Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2
Int J Cancer, 116 (3), 359-67
DOI 10.1002/ijc.21015, PubMed 15800944
Slagsvold T, Aasland R, Hirano S, Bache KG, Raiborg C, Trambaiolo D, Wakatsuki S, Stenmark H (2005)
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain
J Biol Chem, 280 (20), 19600-6
DOI 10.1074/jbc.M501510200, PubMed 15755741
Stige LC, Slagsvold T, Vollestad LA (2005)
Individual fluctuating asymmetry in pied flycatchers (Ficedula hypoleuca) persists across moults, but is not heritable and not related to fitness
Evol. Ecol. Res., 7 (3), 381-406
Voigt B, Timmers AC, Samaj J, Hlavacka A, Ueda T, Preuss M, Nielsen E, Mathur J, Emans N, Stenmark H, Nakano A, Baluska F, Menzel D (2005)
Actin-based motility of endosomes is linked to the polar tip growth of root hairs
Eur J Cell Biol, 84 (6), 609-21
DOI 10.1016/j.ejcb.2004.12.029, PubMed 16032929
Wesche J, Małecki J, Wiedłocha A, Ehsani M, Marcinkowska E, Nilsen T, Olsnes S (2005)
Two nuclear localization signals required for transport from the cytosol to the nucleus of externally added FGF-1 translocated into cells
Biochemistry, 44 (16), 6071-80
DOI 10.1021/bi047403m, PubMed 15835896
Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2005)
Highly stable mutants of human fibroblast growth factor-1 exhibit prolonged biological action
J Mol Biol, 352 (4), 860-75
DOI 10.1016/j.jmb.2005.07.066, PubMed 16126225

Publications 2004

Bache KG, Slagsvold T, Cabezas A, Rosendal KR, Raiborg C, Stenmark H (2004)
The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
Mol Biol Cell, 15 (9), 4337-46
DOI 10.1091/mbc.e04-03-0250, PubMed 15240819
Bache KG, Slagsvold T, Stenmark H (2004)
Defective downregulation of receptor tyrosine kinases in cancer
EMBO J, 23 (14), 2707-12
DOI 10.1038/sj.emboj.7600292, PubMed 15229652
Birkeland HC, Stenmark H (2004)
Protein targeting to endosomes and phagosomes via FYVE and PX domains
Curr Top Microbiol Immunol, 282, 89-115
DOI 10.1007/978-3-642-18805-3_4, PubMed 14594215
Gruenberg J, Stenmark H (2004)
The biogenesis of multivesicular endosomes
Nat Rev Mol Cell Biol, 5 (4), 317-23
DOI 10.1038/nrm1360, PubMed 15071556
Hansen BT, Slagsvold T (2004)
Early learning affects social dominance: interspecifically cross-fostered tits become subdominant
Behav. Ecol., 15 (2), 262-268
DOI 10.1093/beheco/arh010
Johnson HM, Subramaniam PS, Olsnes S, Jans DA (2004)
Trafficking and signaling pathways of nuclear localizing protein ligands and their receptors
Bioessays, 26 (9), 993-1004
DOI 10.1002/bies.20086, PubMed 15351969
Kourmanova AG, Soudarkina OJ, Olsnes S, Kozlov JV (2004)
Cloning and characterization of the genes encoding toxic lectins in mistletoe (Viscum album L)
Eur J Biochem, 271 (12), 2350-60
DOI 10.1111/j.1432-1033.2004.04153.x, PubMed 15182350
Kowanetz K, Crosetto N, Haglund K, Schmidt MHH, Heldin CH, Dikic I (2004)
Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases
J Biol Chem, 279 (31), 32786-95
DOI 10.1074/jbc.M403759200, PubMed 15159412
Loog M, Oskolkov N, O'Farrell F, Ek P, Järv J (2004)
Comparison of cAMP-dependent protein kinase substrate specificity in reaction with proteins and synthetic peptides
Biochim Biophys Acta, 1747 (2), 261-6
DOI 10.1016/j.bbapap.2004.11.016, PubMed 15698961
Olsnes S (2004)
The history of ricin, abrin and related toxins
Toxicon, 44 (4), 361-70
DOI 10.1016/j.toxicon.2004.05.003, PubMed 15302520
Rusten TE, Lindmo K, Juhász G, Sass M, Seglen PO, Brech A, Stenmark H (2004)
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
Dev Cell, 7 (2), 179-92
DOI 10.1016/j.devcel.2004.07.005, PubMed 15296715
Sharma M, Pampinella F, Nemes C, Benharouga M, So J, Du K, Bache KG, Papsin B, Zerangue N, Stenmark H, Lukacs GL (2004)
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes
J Cell Biol, 164 (6), 923-33
DOI 10.1083/jcb.200312018, PubMed 15007060
Simonsen A, Birkeland HC, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A, Stenmark H (2004)
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
J Cell Sci, 117 (Pt 18), 4239-51
DOI 10.1242/jcs.01287, PubMed 15292400
Slagsvold T, Stenmark H (2004)
The structure of an endosomal protein sorter
Dev Cell, 7 (4), 457-8
DOI 10.1016/j.devcel.2004.09.007, PubMed 15469831
Stang E, Blystad FD, Kazazic M, Bertelsen V, Brodahl T, Raiborg C, Stenmark H, Madshus IH (2004)
Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits
Mol Biol Cell, 15 (8), 3591-604
DOI 10.1091/mbc.e04-01-0041, PubMed 15194809
Sørensen V, Brech A, Khnykin D, Kolpakova E, Citores L, Olsnes S (2004)
Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus
J Cell Sci, 117 (Pt 9), 1807-19
DOI 10.1242/jcs.01047, PubMed 15075241
Vieira OV, Harrison RE, Scott CC, Stenmark H, Alexander D, Liu J, Gruenberg J, Schreiber AD, Grinstein S (2004)
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria
Mol Cell Biol, 24 (10), 4593-604
DOI 10.1128/MCB.24.10.4593-4604.2004, PubMed 15121875
Wiedłocha A, Nilsen T, Wesche J, Sørensen V, Małecki J, Marcinkowska E, Olsnes S (2004)
Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1
Mol Biol Cell, 16 (2), 794-810
DOI 10.1091/mbc.e04-05-0389, PubMed 15574884
Wiedłocha A, Sørensen V (2004)
Signaling, internalization, and intracellular activity of fibroblast growth factor
Curr Top Microbiol Immunol, 286, 45-79
DOI 10.1007/978-3-540-69494-6_3, PubMed 15645710
Zakrzewska M, Krowarsch D, Wiedlocha A, Otlewski J (2004)
Design of fully active FGF-1 variants with increased stability
Protein Eng Des Sel, 17 (8), 603-11
DOI 10.1093/protein/gzh076, PubMed 15469994

Publications 2003

Bache KG, Brech A, Mehlum A, Stenmark H (2003)
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
J Cell Biol, 162 (3), 435-42
DOI 10.1083/jcb.200302131, PubMed 12900395
Bache KG, Raiborg C, Mehlum A, Stenmark H (2003)
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
J Biol Chem, 278 (14), 12513-21
DOI 10.1074/jbc.M210843200, PubMed 12551915
Duś D, Krawczenko A, Załecki P, Paprocka M, Wiedłocha A, Goupille C, Kieda C (2003)
IL-7 receptor is present on human microvascular endothelial cells
Immunol Lett, 86 (2), 163-8
DOI 10.1016/s0165-2478(03)00018-x, PubMed 12644318
Gillooly DJ, Raiborg C, Stenmark H (2003)
Phosphatidylinositol 3-phosphate is found in microdomains of early endosomes
Histochem Cell Biol, 120 (6), 445-53
DOI 10.1007/s00418-003-0591-7, PubMed 14618335
González-Gaitán M, Stenmark H (2003)
Endocytosis and signaling: a relationship under development
Cell, 115 (5), 513-21
DOI 10.1016/s0092-8674(03)00932-2, PubMed 14651844
Gregers TF, Nordeng TW, Birkeland HC, Sandlie I, Bakke O (2003)
The cytoplasmic tail of invariant chain modulates antigen processing and presentation
Eur J Immunol, 33 (2), 277-86
DOI 10.1002/immu.200310001, PubMed 12548558
Holme HK, Lindmo K, Kristiansen A, Smidsrod O (2003)
Thermal depolymerization of alginate in the solid state
Carbohydr. Polym., 54 (4), 431-438
DOI 10.1016/S0144-8617(03)00134-6
Kolpakova E, Rusten TE, Olsnes S (2003)
Characterization and tissue expression of acidic fibroblast growth factor binding protein homologue in Drosophila melanogaster
Gene, 310, 185-91
DOI 10.1016/s0378-1119(03)00550-x, PubMed 12801646
Kowanetz K, Szymkiewicz I, Haglund K, Kowanetz M, Husnjak K, Taylor JD, Soubeyran P, Engstrom U, Ladbury JE, Dikic I (2003)
Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors
J Biol Chem, 278 (41), 39735-46
DOI 10.1074/jbc.M304541200, PubMed 12874286
Małecki J, Wesche J, Skjerpen CS, Wiedłocha A, Olsnes S (2003)
Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism
Mol Biol Cell, 15 (2), 801-14
DOI 10.1091/mbc.e03-08-0589, PubMed 14657241
Marchese A, Raiborg C, Santini F, Keen JH, Stenmark H, Benovic JL (2003)
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
Dev Cell, 5 (5), 709-22
DOI 10.1016/s1534-5807(03)00321-6, PubMed 14602072
Marcinkowska E, Wiedlocha A (2003)
Phosphatidylinositol-3 kinase-dependent activation of Akt does not correlate with either high mitogenicity or cell migration induced by FGF-1
Anticancer Res, 23 (5A), 4071-7
PubMed 14666721
Mousavi SA, Brech A, Berg T, Kjeken R (2003)
Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes
Biochem J, 372 (Pt 3), 861-9
DOI 10.1042/BJ20021136, PubMed 12646047
Nilsen T, Slagsvold T, Skjerpen CS, Brech A, Stenmark H, Olsnes S (2003)
Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
J Biol Chem, 279 (6), 4794-801
DOI 10.1074/jbc.M309653200, PubMed 14604990
Olsnes S, Klingenberg O, Wiedłocha A (2003)
Transport of exogenous growth factors and cytokines to the cytosol and to the nucleus
Physiol Rev, 83 (1), 163-82
DOI 10.1152/physrev.00021.2002, PubMed 12506129
Petiot A, Faure J, Stenmark H, Gruenberg J (2003)
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
J Cell Biol, 162 (6), 971-9
DOI 10.1083/jcb.200303018, PubMed 12975344
Raiborg C, Rusten TE, Stenmark H (2003)
Protein sorting into multivesicular endosomes
Curr Opin Cell Biol, 15 (4), 446-55
DOI 10.1016/s0955-0674(03)00080-2, PubMed 12892785
Schedlich LJ, Nilsen T, John AP, Jans DA, Baxter RC (2003)
Phosphorylation of insulin-like growth factor binding protein-3 by deoxyribonucleic acid-dependent protein kinase reduces ligand binding and enhances nuclear accumulation
Endocrinology, 144 (5), 1984-93
DOI 10.1210/en.2002-220798, PubMed 12697706
Storen T, Simonsen A, Royset AK, Lokberg OJ, Svaasand LO, Lindmo T (2003)
Time resolved spectroscopic optical coherence tomography for diffusion measurements
P SOC PHOTO-OPT INS, 4956, 197-204
DOI 10.1117/12.477645

Publications 2002

Bache KG, Raiborg C, Mehlum A, Madshus IH, Stenmark H (2002)
Phosphorylation of Hrs downstream of the epidermal growth factor receptor
Eur J Biochem, 269 (16), 3881-7
DOI 10.1046/j.1432-1033.2002.03046.x, PubMed 12180964
Braathen R, Sorensen V, Brandtzaeg P, Sandlie I, Johansen FE (2002)
The carboxyl-terminal domains of IgA and IgM direct isotype-specific polymerization and interaction with the polymeric immunoglobulin receptor
J Biol Chem, 277 (45), 42755-62
DOI 10.1074/jbc.M205502200, PubMed 12213814
Kauppi M, Simonsen A, Bremnes B, Vieira A, Callaghan J, Stenmark H, Olkkonen VM (2002)
The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
J Cell Sci, 115 (Pt 5), 899-911
DOI 10.1242/jcs.115.5.899, PubMed 11870209
Luk'ianov EV, Viedlokha A, Kuianskaia DV, Olsnes S, Kozlov IuV (2002)
[A short form of the heparin-binding EGF-like growth factor with a changed EGF domain]
Mol Biol (Mosk), 36 (1), 76-83
PubMed 11862716
Luk'yanov EV, Viedlokha A, Kuyavskaya DV, Olsnes S, Kozlov YV (2002)
A short form of the heparin-binding EGF-like growth factor with a changed EGF domain
Mol. Biol., 36 (1), 58-64
DOI 10.1023/A:1014246423243
Małecki J, Wiedłocha A, Wesche J, Olsnes S (2002)
Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1
EMBO J, 21 (17), 4480-90
DOI 10.1093/emboj/cdf472, PubMed 12198150
Marcinkowska E, Wiedłocha A (2002)
Steroid signal transduction activated at the cell membrane: from plants to animals
Acta Biochim Pol, 49 (3), 735-45
PubMed 12422243
Murray JT, Panaretou C, Stenmark H, Miaczynska M, Backer JM (2002)
Role of Rab5 in the recruitment of hVps34/p150 to the early endosome
Traffic, 3 (6), 416-27
DOI 10.1034/j.1600-0854.2002.30605.x, PubMed 12010460
Panopoulou E, Gillooly DJ, Wrana JL, Zerial M, Stenmark H, Murphy C, Fotsis T (2002)
Early endosomal regulation of Smad-dependent signaling in endothelial cells
J Biol Chem, 277 (20), 18046-52
DOI 10.1074/jbc.M107983200, PubMed 11877415
Raiborg C, Bache KG, Gillooly DJ, Madshus IH, Stang E, Stenmark H (2002)
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
Nat Cell Biol, 4 (5), 394-8
DOI 10.1038/ncb791, PubMed 11988743
Raiborg C, Stenmark H (2002)
Hrs and endocytic sorting of ubiquitinated membrane proteins
Cell Struct Funct, 27 (6), 403-8
DOI 10.1247/csf.27.403, PubMed 12576633
Shimokawa N, Okada J, Haglund K, Dikic I, Koibuchi N, Miura M (2002)
Past-A, a novel proton-associated sugar transporter, regulates glucose homeostasis in the brain
J Neurosci, 22 (21), 9160-5
DOI 10.1523/JNEUROSCI.22-21-09160.2002, PubMed 12417639
Skjerpen CS, Nilsen T, Wesche J, Olsnes S (2002)
Binding of FGF-1 variants to protein kinase CK2 correlates with mitogenicity
EMBO J, 21 (15), 4058-69
DOI 10.1093/emboj/cdf402, PubMed 12145206
Skjerpen CS, Wesche J, Olsnes S (2002)
Identification of ribosome-binding protein p34 as an intracellular protein that binds acidic fibroblast growth factor
J Biol Chem, 277 (26), 23864-71
DOI 10.1074/jbc.M112193200, PubMed 11964394
Stenmark H, Aasland R, Driscoll PC (2002)
The phosphatidylinositol 3-phosphate-binding FYVE finger
FEBS Lett, 513 (1), 77-84
DOI 10.1016/s0014-5793(01)03308-7, PubMed 11911884
Wabakken T, Hauge H, Finne EF, Wiedlocha A, Aasheim H (2002)
Expression of human protein tyrosine phosphatase epsilon in leucocytes: a potential ERK pathway-regulating phosphatase
Scand J Immunol, 56 (2), 195-203
DOI 10.1046/j.1365-3083.2002.01126.x, PubMed 12121439
Wesche J (2002)
Retrograde transport of ricin
Int J Med Microbiol, 291 (6-7), 517-21
DOI 10.1078/1438-4221-00161, PubMed 11890552

Publications 2001

Citores L, Khnykin D, Sørensen V, Wesche J, Klingenberg O, Wiedłocha A, Olsnes S (2001)
Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain
J Cell Sci, 114 (Pt 9), 1677-89
DOI 10.1242/jcs.114.9.1677, PubMed 11398757
Falnes PØ, Wesche J, Olsnes S (2001)
Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment
Biochemistry, 40 (14), 4349-58
DOI 10.1021/bi002443l, PubMed 11284691
Gillooly DJ, Simonsen A, Stenmark H (2001)
Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
Biochem J, 355 (Pt 2), 249-58
DOI 10.1042/0264-6021:3550249, PubMed 11284710
Gillooly DJ, Simonsen A, Stenmark H (2001)
Phosphoinositides and phagocytosis
J Cell Biol, 155 (1), 15-7
DOI 10.1083/jcb.200109001, PubMed 11581282
Gillooly DJ, Stenmark H (2001)
Cell biology. A lipid oils the endocytosis machine
Science, 291 (5506), 993-4
DOI 10.1126/science.291.5506.993, PubMed 11232585
Kim DH, Eu YJ, Yoo CM, Kim YW, Pih KT, Jin JB, Kim SJ, Stenmark H, Hwang I (2001)
Trafficking of phosphatidylinositol 3-phosphate from the trans-Golgi network to the lumen of the central vacuole in plant cells
Plant Cell, 13 (2), 287-301
DOI 10.1105/tpc.13.2.287, PubMed 11226186
Kjeken R, Mousavi SA, Brech A, Gjøen T, Berg T (2001)
Fluid phase endocytosis of [125I]iodixanol in rat liver parenchymal, endothelial and Kupffer cells
Cell Tissue Res, 304 (2), 221-30
DOI 10.1007/s004410100348, PubMed 11396716
Kjeken R, Mousavi SA, Brech A, Griffiths G, Berg T (2001)
Wortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cells
Biochem J, 357 (Pt 2), 497-503
DOI 10.1042/0264-6021:3570497, PubMed 11439100
Loukianov EV, Wiedlocha A, Olsnes S, Kozlov YV (2001)
Two farms of the heparin-binding EGF-like growth factor precursor, a receptor for diphtheria toxin
Mol. Biol., 35 (1), 122-129
DOI 10.1023/A:1004819321876
Luk'ianov EV, Viedlokha A, Olsnes S, Kozlov IuV (2001)
[Two forms of precursors of a heparin-binding EGF-like growth factor-diphtheria toxin receptor]
Mol Biol (Mosk), 35 (1), 136-45
PubMed 11234372
Marcinkowska E, Chrobak A, Wiedłocha A (2001)
Evading apoptosis by calcitriol-differentiated human leukemic HL-60 cells is not mediated by changes in CD95 receptor system but by increased sensitivity of these cells to insulin
Exp Cell Res, 270 (1), 119-27
DOI 10.1006/excr.2001.5335, PubMed 11597134
Mousavi SA, Kjeken R, Berg TO, Seglen PO, Berg T, Brech A (2001)
Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy
Biochim Biophys Acta, 1510 (1-2), 243-57
DOI 10.1016/s0005-2736(00)00354-0, PubMed 11342162
Olsnes S, Kozlov JV (2001)
Ricin
Toxicon, 39 (11), 1723-8
DOI 10.1016/s0041-0101(01)00158-1, PubMed 11595634
Olsnes S, Wesche J (2001)
Microbiology. Fighting anthrax with a mutant toxin
Science, 292 (5517), 647-8
DOI 10.1126/science.1060857, PubMed 11330322
Pattni K, Jepson M, Stenmark H, Banting G (2001)
A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells
Curr Biol, 11 (20), 1636-42
DOI 10.1016/s0960-9822(01)00486-9, PubMed 11676927
Raiborg C, Bache KG, Mehlum A, Stang E, Stenmark H (2001)
Hrs recruits clathrin to early endosomes
EMBO J, 20 (17), 5008-21
DOI 10.1093/emboj/20.17.5008, PubMed 11532964
Raiborg C, Bache KG, Mehlum A, Stenmark H (2001)
Function of Hrs in endocytic trafficking and signalling
Biochem Soc Trans, 29 (Pt 4), 472-5
DOI 10.1042/bst0290472, PubMed 11498011
Raiborg C, Bremnes B, Mehlum A, Gillooly DJ, D'Arrigo A, Stang E, Stenmark H (2001)
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes
J Cell Sci, 114 (Pt 12), 2255-63
DOI 10.1242/jcs.114.12.2255, PubMed 11493665
Simonsen A, Stenmark H (2001)
PX domains: attracted by phosphoinositides
Nat Cell Biol, 3 (8), E179-82
DOI 10.1038/35087112, PubMed 11483972
Simonsen A, Wurmser AE, Emr SD, Stenmark H (2001)
The role of phosphoinositides in membrane transport
Curr Opin Cell Biol, 13 (4), 485-92
DOI 10.1016/s0955-0674(00)00240-4, PubMed 11454456
Slagsvold T, Kraus I, Frønsdal K, Saatcioglu F (2001)
DNA binding-independent transcriptional activation by the androgen receptor through triggering of coactivators
J Biol Chem, 276 (33), 31030-6
DOI 10.1074/jbc.M104310200, PubMed 11429409
Stenmark H (2001)
Introduction. Trafficking of lipids
Semin Cell Dev Biol, 12 (2), 135-7
DOI 10.1006/scdb.2000.0230, PubMed 11292379
Stenmark H, Gillooly DJ (2001)
Intracellular trafficking and turnover of phosphatidylinositol 3-phosphate
Semin Cell Dev Biol, 12 (2), 193-9
DOI 10.1006/scdb.2000.0236, PubMed 11292385
Stenmark H, Olkkonen VM (2001)
The Rab GTPase family
Genome Biol, 2 (5), REVIEWS3007
DOI 10.1186/gb-2001-2-5-reviews3007, PubMed 11387043
Stenmark H, Olkkonen VM (2001)
The Rab GTPase family
Genome Biol., 2 (5), 3007.1

Publications 2000

Day PJ, Owens SR, Wesche J, Olsnes S, Roberts LM, Lord JM (2000)
An interaction between ricin and calreticulin that may have implications for toxin trafficking
J Biol Chem, 276 (10), 7202-8
DOI 10.1074/jbc.M009499200, PubMed 11113144
Duclos S, Diez R, Garin J, Papadopoulou B, Descoteaux A, Stenmark H, Desjardins M (2000)
Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages
J Cell Sci, 113 Pt 19, 3531-41
DOI 10.1242/jcs.113.19.3531, PubMed 10984443
Eliassen TM, Frøystad MK, Dannevig BH, Jankowska M, Brech A, Falk K, Romøren K, Gjøen T (2000)
Initial events in infectious salmon anemia virus infection: evidence for the requirement of a low-pH step
J Virol, 74 (1), 218-27
DOI 10.1128/jvi.74.1.218-227.2000, PubMed 10590109
Falnes PO, Ariansen S, Sandvig K, Olsnes S (2000)
Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin
J Biol Chem, 275 (6), 4363-8
DOI 10.1074/jbc.275.6.4363, PubMed 10660606
Fengsrud M, Erichsen ES, Berg TO, Raiborg C, Seglen PO (2000)
Ultrastructural characterization of the delimiting membranes of isolated autophagosomes and amphisomes by freeze-fracture electron microscopy
Eur J Cell Biol, 79 (12), 871-82
DOI 10.1078/0171-9335-00125, PubMed 11152279
Fengsrud M, Raiborg C, Berg TO, Strømhaug PE, Ueno T, Erichsen ES, Seglen PO (2000)
Autophagosome-associated variant isoforms of cytosolic enzymes
Biochem J, 352 Pt 3 (Pt 3), 773-81
DOI 10.1042/0264-6021:3520773, PubMed 11104685
Gaullier JM, Ronning E, Gillooly DJ, Stenmark H (2000)
Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues
J Biol Chem, 275 (32), 24595-600
DOI 10.1074/jbc.M906554199, PubMed 10807926
Gillooly DJ, Morrow IC, Lindsay M, Gould R, Bryant NJ, Gaullier JM, Parton RG, Stenmark H (2000)
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
EMBO J, 19 (17), 4577-88
DOI 10.1093/emboj/19.17.4577, PubMed 10970851
Klingenberg O, Wiedlocha A, Rapak A, Khnykin D, Citores L, Olsnes S (2000)
Requirement for C-terminal end of fibroblast growth factor receptor 4 in translocation of acidic fibroblast growth factor to cytosol and nucleus
J Cell Sci, 113 ( Pt 10), 1827-38
DOI 10.1242/jcs.113.10.1827, PubMed 10769213
Klingenberg O, Wiedocha A, Citores L, Olsnes S (2000)
Requirement of phosphatidylinositol 3-kinase activity for translocation of exogenous aFGF to the cytosol and nucleus
J Biol Chem, 275 (16), 11972-80
DOI 10.1074/jbc.275.16.11972, PubMed 10766827
Kolpakova E, Frengen E, Stokke T, Olsnes S (2000)
Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein
Biochem J, 352 Pt 3 (Pt 3), 629-35
DOI 10.1042/0264-6021:3520629, PubMed 11104667
Løvdal T, Andersen E, Brech A, Berg T (2000)
Fc receptor mediated endocytosis of small soluble immunoglobulin G immune complexes in Kupffer and endothelial cells from rat liver
J Cell Sci, 113 ( Pt 18), 3255-66
DOI 10.1242/jcs.113.18.3255, PubMed 10954423
Olsnes S, Falnes PO (2000)
Probing pores with peptide plugs. Topology of membrane-inserted diphtheria toxin
J Gen Physiol, 115 (4), 417-20
DOI 10.1085/jgp.115.4.417, PubMed 10736309
Prosch-Danielsen L, Simonsen A (2000)
Palaeoecological investigations towards the reconstruction of the history of forest clearances and coastal heathlands in south-western Norway
Veg. Hist. Archaeobot., 9 (4), 189-204
DOI 10.1007/BF01294634
Slagsvold T, Kraus I, Bentzen T, Palvimo J, Saatcioglu F (2000)
Mutational analysis of the androgen receptor AF-2 (activation function 2) core domain reveals functional and mechanistic differences of conserved residues compared with other nuclear receptors
Mol Endocrinol, 14 (10), 1603-17
DOI 10.1210/mend.14.10.0544, PubMed 11043576
Stenmark H (2000)
Cycling lipids
Curr Biol, 10 (2), R57-9
DOI 10.1016/s0960-9822(00)00279-7, PubMed 10662657
Urbé S, Mills IG, Stenmark H, Kitamura N, Clague MJ (2000)
Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate
Mol Cell Biol, 20 (20), 7685-92
DOI 10.1128/MCB.20.20.7685-7692.2000, PubMed 11003664
Wesche J, Wiedłocha A, Falnes PO, Choe S, Olsnes S (2000)
Externally added aFGF mutants do not require extensive unfolding for transport to the cytosol and the nucleus in NIH/3T3 cells
Biochemistry, 39 (49), 15091-100
DOI 10.1021/bi001831k, PubMed 11106487

Publications 1999

Callaghan J, Nixon S, Bucci C, Toh BH, Stenmark H (1999)
Direct interaction of EEA1 with Rab5b
Eur J Biochem, 265 (1), 361-6
DOI 10.1046/j.1432-1327.1999.00743.x, PubMed 10491193
Callaghan J, Simonsen A, Gaullier JM, Toh BH, Stenmark H (1999)
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer
Biochem J, 338 ( Pt 2) (Pt 2), 539-43
DOI 10.1042/0264-6021:3380539, PubMed 10024533
Citores L, Wesche J, Kolpakova E, Olsnes S (1999)
Uptake and intracellular transport of acidic fibroblast growth factor: evidence for free and cytoskeleton-anchored fibroblast growth factor receptors
Mol Biol Cell, 10 (11), 3835-48
DOI 10.1091/mbc.10.11.3835, PubMed 10564275
Corvera S, D'Arrigo A, Stenmark H (1999)
Phosphoinositides in membrane traffic
Curr Opin Cell Biol, 11 (4), 460-5
DOI 10.1016/S0955-0674(99)80066-0, PubMed 10449332
Falnes PO, Welker R, Kräusslich HG, Olsnes S (1999)
Toxins that are activated by HIV type-1 protease through removal of a signal for degradation by the N-end-rule pathway
Biochem J, 343 Pt 1 (Pt 1), 199-207
DOI 10.1042/0264-6021:3430199, PubMed 10493930
Gaullier JM, Gillooly D, Simonsen A, Stenmark H (1999)
Regulation of endocytic membrane traffic by phosphatidylinositol 3-phosphate
Biochem Soc Trans, 27 (4), 666-70
DOI 10.1042/bst0270666, PubMed 10917663
Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H (1999)
FYVE finger proteins as effectors of phosphatidylinositol 3-phosphate
Chem Phys Lipids, 98 (1-2), 87-94
DOI 10.1016/s0009-3084(99)00021-3, PubMed 10358931
Klingenberg O, Wiedlocha A, Olsnes S (1999)
Effects of mutations of a phosphorylation site in an exposed loop in acidic fibroblast growth factor
J Biol Chem, 274 (25), 18081-6
DOI 10.1074/jbc.274.25.18081, PubMed 10364261
Olsnes S (1999)
[The Nobel Prize in physiology and medicine]
Tidsskr Nor Laegeforen, 119 (30), 4450
PubMed 10827478
Simonsen A, Gaullier JM, D'Arrigo A, Stenmark H (1999)
The Rab5 effector EEA1 interacts directly with syntaxin-6
J Biol Chem, 274 (41), 28857-60
DOI 10.1074/jbc.274.41.28857, PubMed 10506127
Stenmark H, Aasland R (1999)
FYVE-finger proteins--effectors of an inositol lipid
J Cell Sci, 112 ( Pt 23), 4175-83
DOI 10.1242/jcs.112.23.4175, PubMed 10564636
Synnes M, Prydz K, Løvdal T, Brech A, Berg T (1999)
Fluid phase endocytosis and galactosyl receptor-mediated endocytosis employ different early endosomes
Biochim Biophys Acta, 1421 (2), 317-28
DOI 10.1016/s0005-2736(99)00134-0, PubMed 10518701
Wesche J, Rapak A, Olsnes S (1999)
Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol
J Biol Chem, 274 (48), 34443-9
DOI 10.1074/jbc.274.48.34443, PubMed 10567425
Wiedłocha A (1999)
Following angiogenin during angiogenesis: a journey from the cell surface to the nucleolus
Arch Immunol Ther Exp (Warsz), 47 (5), 299-305
PubMed 10604235

Publications 1998

Falnes PO, Olsnes S (1998)
Modulation of the intracellular stability and toxicity of diphtheria toxin through degradation by the N-end rule pathway
EMBO J, 17 (2), 615-25
DOI 10.1093/emboj/17.2.615, PubMed 9430652
Frønsdal K, Engedal N, Slagsvold T, Saatcioglu F (1998)
CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1
J Biol Chem, 273 (48), 31853-9
DOI 10.1074/jbc.273.48.31853, PubMed 9822653
Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H, Aasland R (1998)
FYVE fingers bind PtdIns(3)P
Nature, 394 (6692), 432-3
DOI 10.1038/28767, PubMed 9697764
Gournier H, Stenmark H, Rybin V, Lippé R, Zerial M (1998)
Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion
EMBO J, 17 (7), 1930-40
DOI 10.1093/emboj/17.7.1930, PubMed 9524116
Janson IM, Toomik R, O'Farrell F, Ek P (1998)
KDEL motif interacts with a specific sequence in mammalian erd2 receptor
Biochem Biophys Res Commun, 247 (2), 447-51
DOI 10.1006/bbrc.1998.8809, PubMed 9642148
Klingenberg O, Widlocha A, Rapak A, Muñoz R, Falnes P, Olsnes S (1998)
Inability of the acidic fibroblast growth factor mutant K132E to stimulate DNA synthesis after translocation into cells
J Biol Chem, 273 (18), 11164-72
DOI 10.1074/jbc.273.18.11164, PubMed 9556604
Kolpakova E, Wiedłocha A, Stenmark H, Klingenberg O, Falnes PO, Olsnes S (1998)
Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor
Biochem J, 336 ( Pt 1) (Pt 1), 213-22
DOI 10.1042/bj3360213, PubMed 9806903
Loukianov EV, Loukianova T, Wiedlocha A, Olsnes S (1998)
Variation in the proregion structure of heparin-binding EGF-like growth factor precursors
Gene, 212 (1), 1-4
DOI 10.1016/s0378-1119(98)00139-5, PubMed 9661657
Marcinkowska E, Wiedlocha A, Radzikowski C (1998)
Evidence that phosphatidylinositol 3-kinase and p70S6K protein are involved in differentiation of HL-60 cells induced by calcitriol
Anticancer Res, 18 (5A), 3507-14
PubMed 9858932
Mathiesen RH, Mo F, Eikenes A, Nyborg T, Larsen HB (1998)
Existence of two crystal structures of the complex alpha-D-glucose center dot NaCl center dot H2O (2 : 1 : 1) verified by three-beam diffraction experiments
Acta Crystallogr. Sect. A, 54, 338-347
DOI 10.1107/S0108767397018849
Olsnes S (1998)
Shiga and Shiga-like toxins
RECENT ADVANCES IN THE PATHOGENESIS OF GASTROINTESTINAL BACTERIAL INFECTIONS, 143-153
Simonsen A, Bremnes B, Rønning E, Aasland R, Stenmark H (1998)
Syntaxin-16, a putative Golgi t-SNARE
Eur J Cell Biol, 75 (3), 223-31
DOI 10.1016/S0171-9335(98)80116-7, PubMed 9587053
Simonsen A, Lippé R, Christoforidis S, Gaullier JM, Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H (1998)
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
Nature, 394 (6692), 494-8
DOI 10.1038/28879, PubMed 9697774
Vitale G, Rybin V, Christoforidis S, Thornqvist P, McCaffrey M, Stenmark H, Zerial M (1998)
Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5
EMBO J, 17 (7), 1941-51
DOI 10.1093/emboj/17.7.1941, PubMed 9524117
Waite RL, Sentry JW, Stenmark H, Toh BH (1998)
Autoantibodies to a novel early endosome antigen 1
Clin Immunol Immunopathol, 86 (1), 81-7
DOI 10.1006/clin.1997.4455, PubMed 9434799
Wesche J, Elliott JL, Falnes PO, Olsnes S, Collier RJ (1998)
Characterization of membrane translocation by anthrax protective antigen
Biochemistry, 37 (45), 15737-46
DOI 10.1021/bi981436i, PubMed 9843379
Wiedłocha A (1998)
Novel protein toxin-based strategy for development of cytotoxic T lymphocyte vaccines
Arch Immunol Ther Exp (Warsz), 46 (6), 341-6
PubMed 9883312
Zacchi P, Stenmark H, Parton RG, Orioli D, Lim F, Giner A, Mellman I, Zerial M, Murphy C (1998)
Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells
J Cell Biol, 140 (5), 1039-53
DOI 10.1083/jcb.140.5.1039, PubMed 9490718
Zalecki P, Radzikowski C, Olsnes S, Wiedłocha A (1998)
Modulation by interleukin-2 of cellular response to fibroblast growth factor-1 in F69-3 fibrosarcoma cells
Exp Cell Res, 244 (1), 61-70
DOI 10.1006/excr.1998.4187, PubMed 9770349

Publications 1997

D'Arrigo A, Bucci C, Toh BH, Stenmark H (1997)
Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes
Eur J Cell Biol, 72 (2), 95-103
PubMed 9157016
Garred O, Dubinina E, Polesskaya A, Olsnes S, Kozlov J, Sandvig K (1997)
Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells
J Biol Chem, 272 (17), 11414-9
DOI 10.1074/jbc.272.17.11414, PubMed 9111051
Horiuchi H, Lippé R, McBride HM, Rubino M, Woodman P, Stenmark H, Rybin V, Wilm M, Ashman K, Mann M, Zerial M (1997)
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function
Cell, 90 (6), 1149-59
DOI 10.1016/s0092-8674(00)80380-3, PubMed 9323142
Lanzrein M, Falnes PO, Sand O, Olsnes S (1997)
Structure-function relationship of the ion channel formed by diphtheria toxin in Vero cell membranes
J Membr Biol, 156 (2), 141-8
DOI 10.1007/s002329900196, PubMed 9075645
Lemichez E, Bomsel M, Devilliers G, vanderSpek J, Murphy JR, Lukianov EV, Olsnes S, Boquet P (1997)
Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery
Mol Microbiol, 23 (3), 445-57
DOI 10.1111/j.1365-2958.1997.tb02669.x, PubMed 9044279
Loukianov E, Loukianova T, Wiedlocha A, Olsnes S (1997)
Expression of mRNA for a short form of heparin-binding EGF-like growth factor
Gene, 195 (1), 81-6
DOI 10.1016/s0378-1119(97)00161-3, PubMed 9300824
Marcinkowska E, Wiedłocha A, Radzikowski C (1997)
1,25-Dihydroxyvitamin D3 induced activation and subsequent nuclear translocation of MAPK is upstream regulated by PKC in HL-60 cells
Biochem Biophys Res Commun, 241 (2), 419-26
DOI 10.1006/bbrc.1997.7832, PubMed 9425286
Muñoz R, Klingenberg O, Wiedłocha A, Rapak A, Falnes PO, Olsnes S (1997)
Effect of mutation of cytoplasmic receptor domain and of genistein on transport of acidic fibroblast growth factor into cells
Oncogene, 15 (5), 525-36
DOI 10.1038/sj.onc.1201226, PubMed 9247306
Olkkonen VM, Stenmark H (1997)
Role of Rab GTPases in membrane traffic
Int Rev Cytol, 176, 1-85
DOI 10.1016/s0074-7696(08)61608-3, PubMed 9394917
Polesskaia AN, Garred O, Olsnes S, Kozlov IuV (1997)
[Self-inhibiting N-glycosidase activity of shigella toxin]
Mol Biol (Mosk), 31 (3), 528-35
PubMed 9297098
Polesskaya AN, Garred O, Olsnes S, Kozlov YV (1997)
Self-inhibition of N-glycosidase activity of shiga toxin
Mol. Biol., 31 (3), 441-447
Rapak A, Falnes PO, Olsnes S (1997)
Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol
Proc Natl Acad Sci U S A, 94 (8), 3783-8
DOI 10.1073/pnas.94.8.3783, PubMed 9108055
Wiedłocha A (1997)
Diphtheria toxin as a molecular tool in the study of acidic fibroblast growth factor signalling
Arch Immunol Ther Exp (Warsz), 45 (5-6), 391-409
PubMed 9437495

Publications 1996

Berg T, Gudmundsen O, Brech A, Kjeken R, Gjøen T (1996)
Clathrin-dependent and clathrin-independent endocytosis in liver cells
Z Gastroenterol, 34 Suppl 3, 92-4
PubMed 8767476
Klingenberg O, Olsnes S (1996)
Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin
Biochem J, 313 ( Pt 2) (Pt 2), 647-53
DOI 10.1042/bj3130647, PubMed 8573105
Lanzrein M, Sand O, Olsnes S (1996)
GPI-anchored diphtheria toxin receptor allows membrane translocation of the toxin without detectable ion channel activity
EMBO J, 15 (4), 725-34
DOI 10.1002/j.1460-2075.1996.tb00408.x, PubMed 8631294
Stenmark H, Aasland R, Toh BH, D'Arrigo A (1996)
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger
J Biol Chem, 271 (39), 24048-54
DOI 10.1074/jbc.271.39.24048, PubMed 8798641
Tjelle TE, Brech A, Juvet LK, Griffiths G, Berg T (1996)
Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation
J Cell Sci, 109 ( Pt 12), 2905-14
DOI 10.1242/jcs.109.12.2905, PubMed 9013338
Waldum HL, Osmundsen H, Olsnes S, Sand O (1996)
[The Anders Jahre medical awarad 1996]
Tidsskr Nor Laegeforen, 116 (23), 2804-6
PubMed 8928170
Wiedłocha A (1996)
Retrograde transport of acidic fibroblast growth factor as a part of the growth factor signaling
Arch Immunol Ther Exp (Warsz), 44 (4), 201-7
PubMed 9017159
Wiedłocha A, Falnes PO, Rapak A, Muñoz R, Klingenberg O, Olsnes S (1996)
Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization
Mol Cell Biol, 16 (1), 270-80
DOI 10.1128/MCB.16.1.270, PubMed 8524304

Publications 1995

Barnett YA, Brennan LA, O'Farrell F, Hannigan BM (1995)
Oxidant-induced stress response in lymphoid cells
Biochem Mol Biol Int, 37 (2), 273-81
PubMed 8673010
ERIKSEN S, SAND O, LANZREIN M, SANDVIG K, OLSNES S (1995)
CELL PENETRATION OF BACTERIAL PROTEIN TOXINS - RESPONSE
Trends Microbiol., 3 (5), 167-168
DOI 10.1016/S0966-842X(00)88912-X
Falnes PO, Olsnes S (1995)
Cell-mediated reduction and incomplete membrane translocation of diphtheria toxin mutants with internal disulfides in the A fragment
J Biol Chem, 270 (35), 20787-93
DOI 10.1074/jbc.270.35.20787, PubMed 7657662
Falnes PO, Wiedłocha A, Rapak A, Olsnes S (1995)
Farnesylation of CaaX-tagged diphtheria toxin A-fragment as a measure of transfer to the cytosol
Biochemistry, 34 (35), 11152-9
DOI 10.1021/bi00035a021, PubMed 7669773
Garred O, Dubinina E, Holm PK, Olsnes S, van Deurs B, Kozlov JV, Sandvig K (1995)
Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
Exp Cell Res, 218 (1), 39-49
DOI 10.1006/excr.1995.1128, PubMed 7737376
Holen I, Gordon PB, Strømhaug PE, Berg TO, Fengsrud M, Brech A, Roos N, Berg T, Seglen PO (1995)
Inhibition of asialoglycoprotein endocytosis and degradation in rat hepatocytes by protein phosphatase inhibitors
Biochem J, 311 ( Pt 1) (Pt 1), 317-26
DOI 10.1042/bj3110317, PubMed 7575471
Kjeken R, Brech A, Løvdal T, Roos N, Berg T (1995)
Involvement of early and late lysosomes in the degradation of mannosylated ligands by rat liver endothelial cells
Exp Cell Res, 216 (2), 290-8
DOI 10.1006/excr.1995.1037, PubMed 7843273
Lanzrein M, Garred O, Olsnes S, Sandvig K (1995)
Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells
Biochem J, 310 ( Pt 1) (Pt 1), 285-9
DOI 10.1042/bj3100285, PubMed 7646457
Mu FT, Callaghan JM, Steele-Mortimer O, Stenmark H, Parton RG, Campbell PL, McCluskey J, Yeo JP, Tock EP, Toh BH (1995)
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif
J Biol Chem, 270 (22), 13503-11
DOI 10.1074/jbc.270.22.13503, PubMed 7768953
Singer-Krüger B, Stenmark H, Zerial M (1995)
Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway
J Cell Sci, 108 ( Pt 11), 3509-21
DOI 10.1242/jcs.108.11.3509, PubMed 8586662
Valdizan EM, Loukianov EV, Olsnes S (1995)
Induction of toxin sensitivity in insect cells by infection with baculovirus encoding diphtheria toxin receptor
J Biol Chem, 270 (28), 16879-85
DOI 10.1074/jbc.270.28.16879, PubMed 7622504
Vitale G, Alexandrov K, Ullrich O, Horiuchi H, Giner A, Dobson C, Baykova O, Gournier H, Stenmark H, Zerial M (1995)
The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic
Cold Spring Harb Symp Quant Biol, 60, 211-20
DOI 10.1101/sqb.1995.060.01.024, PubMed 8824393
Wiedłocha A, Falnes PO, Rapak A, Klingenberg O, Muñoz R, Olsnes S (1995)
Translocation of cytosol of exogenous, CAAX-tagged acidic fibroblast growth factor
J Biol Chem, 270 (51), 30680-5
DOI 10.1074/jbc.270.51.30680, PubMed 8530506

Publications 1994

de Hoop MJ, Huber LA, Stenmark H, Williamson E, Zerial M, Parton RG, Dotti CG (1994)
The involvement of the small GTP-binding protein Rab5a in neuronal endocytosis
Neuron, 13 (1), 11-22
DOI 10.1016/0896-6273(94)90456-1, PubMed 8043272
Eriksen S, Olsnes S, Sandvig K, Sand O (1994)
Diphtheria toxin at low pH depolarizes the membrane, increases the membrane conductance and induces a new type of ion channel in Vero cells
EMBO J, 13 (19), 4433-9
DOI 10.1002/j.1460-2075.1994.tb06765.x, PubMed 7523112
Falnes PO, Choe S, Madshus IH, Wilson BA, Olsnes S (1994)
Inhibition of membrane translocation of diphtheria toxin A-fragment by internal disulfide bridges
J Biol Chem, 269 (11), 8402-7
PubMed 8132565
Madshus IH, Wiedlocha A, Sandvig K (1994)
Intermediates in translocation of diphtheria toxin across the plasma membrane
J Biol Chem, 269 (6), 4648-52
PubMed 7508447
Singer-Krüger B, Stenmark H, Düsterhöft A, Philippsen P, Yoo JS, Gallwitz D, Zerial M (1994)
Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast
J Cell Biol, 125 (2), 283-98
DOI 10.1083/jcb.125.2.283, PubMed 8163546
Wiedłocha A, Falnes PO, Madshus IH, Sandvig K, Olsnes S (1994)
Dual mode of signal transduction by externally added acidic fibroblast growth factor
Cell, 76 (6), 1039-51
DOI 10.1016/0092-8674(94)90381-6, PubMed 7511061

Publications 1993

Ariansen S, Afanasiev BN, Moskaug JO, Stenmark H, Madshus IH, Olsnes S (1993)
Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region
Biochemistry, 32 (1), 83-90
DOI 10.1021/bi00052a012, PubMed 8418864
Aullo P, Giry M, Olsnes S, Popoff MR, Kocks C, Boquet P (1993)
A chimeric toxin to study the role of the 21 kDa GTP binding protein rho in the control of actin microfilament assembly
EMBO J, 12 (3), 921-31
DOI 10.1002/j.1460-2075.1993.tb05733.x, PubMed 8458345
Banning DP, O'Farrell F, Gooderham NJ (1993)
Activation of the food derived carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by rat pleural cavity inflammatory cells
Carcinogenesis, 14 (12), 2457-62
DOI 10.1093/carcin/14.12.2457, PubMed 8269612
BERG T, BRECH A, KJEKEN R, ROOS N (1993)
PRELYSOSOMAL DEGRADATION IN RAT-LIVER ENDOTHELIAL-CELLS
CELLS OF THE HEPATIC SINUSOID, VOL 4, 426-430
Esbensen QY, Falnes PO, Olsnes S, Madshus IH (1993)
Subcloning and characterization of the binding domain of fragment B of diphtheria toxin
Biochem J, 294 ( Pt 3) (Pt 3), 663-6
DOI 10.1042/bj2940663, PubMed 8379922
Loukianov EV, Olsnes S (1993)
New cloning opportunities with the use of noncomplementary SfiI adaptors
Biotechniques, 15 (6), 980-2
PubMed 8292350
Ludt J, Sandvig K, Olsnes S (1993)
Rapid increase in pH set-point of the Na(+)-in-dependent chloride/bicarbonate antiporter in Vero cells exposed to heat shock
J Membr Biol, 134 (2), 143-53
DOI 10.1007/BF00232750, PubMed 8411117
Melby EL, Jacobsen J, Olsnes S, Sandvig K (1993)
Entry of protein toxins in polarized epithelial cells
Cancer Res, 53 (8), 1755-60
PubMed 8467493
Moskaug JO, Prydz K, Olsnes S (1993)
Rapid cellular removal of a membrane-inserted foreign polypeptide
Biochem J, 291 ( Pt 2) (Pt 2), 473-7
DOI 10.1042/bj2910473, PubMed 8484728
Olsnes S, van Deurs B, Sandvig K (1993)
Protein toxins acting on intracellular targets: cellular uptake and translocation to the cytosol
Med Microbiol Immunol, 182 (2), 51-61
DOI 10.1007/BF00189373, PubMed 8392658
Ullrich O, Stenmark H, Alexandrov K, Huber LA, Kaibuchi K, Sasaki T, Takai Y, Zerial M (1993)
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins
J Biol Chem, 268 (24), 18143-50
PubMed 8349690
Zerial M, Stenmark H (1993)
Rab GTPases in vesicular transport
Curr Opin Cell Biol, 5 (4), 613-20
DOI 10.1016/0955-0674(93)90130-i, PubMed 8257602

Publications 1992

Falnes PO, Madshus IH, Sandvig K, Olsnes S (1992)
Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels
J Biol Chem, 267 (17), 12284-90
PubMed 1376320
Jonas L, Walzel H, Bremer H, Wiedlocha A (1992)
Comparative studies on internalization of gold labelled mistletoe lectin I (MLI), its subunits, and of an immunotoxin into mouse L 1210V leukemia cells
Acta Histochem, 92 (1), 46-53
DOI 10.1016/S0065-1281(11)80140-6, PubMed 1580141
Madshus IH, Olsnes S, Stenmark H (1992)
Membrane translocation of diphtheria toxin carrying passenger protein domains
Infect Immun, 60 (8), 3296-302
DOI 10.1128/iai.60.8.3296-3302.1992, PubMed 1639497
Madshus IH, Stenmark H (1992)
Entry of ADP-ribosylating toxins into cells
Curr Top Microbiol Immunol, 175, 1-26
DOI 10.1007/978-3-642-76966-5_1, PubMed 1378368
O'Brien AD, Tesh VL, Donohue-Rolfe A, Jackson MP, Olsnes S, Sandvig K, Lindberg AA, Keusch GT (1992)
Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis
Curr Top Microbiol Immunol, 180, 65-94
DOI 10.1007/978-3-642-77238-2_4, PubMed 1324134
Olsnes S, Frankel AE (1992)
Genetically engineered toxins in perspective
Targeted Diagn Ther, 7, 465-77
PubMed 1633307
Paprocka M, Wiedłocha A, Walzel H, Radzikowski C (1992)
The activity of two immunotoxins composed of monoclonal antibody MoAb-16 and A-chain of ricin (MoAb-16-RTA) or A-chain of mistletoe lectin I (MoAb-16-MLIA)
Arch Immunol Ther Exp (Warsz), 40 (3-4), 223-7
PubMed 1300987
Stenmark H, Afanasiev BN, Ariansen S, Olsnes S (1992)
Association between diphtheria toxin A- and B-fragment and their fusion proteins
Biochem J, 281 ( Pt 3) (Pt 3), 619-25
DOI 10.1042/bj2810619, PubMed 1536643
Stenmark H, Ariansen S, Afanasiev BN, Olsnes S (1992)
Interactions of diphtheria toxin B-fragment with cells. Role of amino- and carboxyl-terminal regions
J Biol Chem, 267 (13), 8957-62
PubMed 1374382
Wiedlocha A, Madshus IH, Mach H, Middaugh CR, Olsnes S (1992)
Tight folding of acidic fibroblast growth factor prevents its translocation to the cytosol with diphtheria toxin as vector
EMBO J, 11 (13), 4835-42
DOI 10.1002/j.1460-2075.1992.tb05589.x, PubMed 1281450

Publications 1991

Ludt J, Tønnessen TI, Sandvig K, Olsnes S (1991)
Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport
J Membr Biol, 119 (2), 179-86
DOI 10.1007/BF01871417, PubMed 2046087
Madshus IH, Stenmark H, Sandvig K, Olsnes S (1991)
Entry of diphtheria toxin-protein A chimeras into cells
J Biol Chem, 266 (26), 17446-53
PubMed 1894632
Melby EL, Prydz K, Olsnes S, Sandvig K (1991)
Effect of monensin on ricin and fluid phase transport in polarized MDCK cells
J Cell Biochem, 47 (3), 251-60
DOI 10.1002/jcb.240470311, PubMed 1791187
Moskaug JO, Stenmark H, Olsnes S (1991)
Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions
J Biol Chem, 266 (4), 2652-9
PubMed 1990012
Olsnes S, Kozlov JV, van Deurs B, Sandvig K (1991)
Bacterial protein toxins acting on intracellular targets
Semin Cell Biol, 2 (1), 7-14
PubMed 1954345
Stenmark H, Moskaug JO, Madshus IH, Sandvig K, Olsnes S (1991)
Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
J Cell Biol, 113 (5), 1025-32
DOI 10.1083/jcb.113.5.1025, PubMed 2040642
Stenmark H, Olsnes S, Madshus IH (1991)
Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding
Mol Microbiol, 5 (3), 595-606
DOI 10.1111/j.1365-2958.1991.tb00730.x, PubMed 1646374
Wiedłocha A, Sandvig K, Walzel H, Radzikowsky C, Olsnes S (1991)
Internalization and action of an immunotoxin containing mistletoe lectin A-chain
Cancer Res, 51 (3), 916-20
PubMed 1988131

Publications 1990

Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1990)
Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
J Physiol (Paris), 84 (3), 191-6
PubMed 1705980
Olsnes S, Stenmark H, Moskaug JO, McGill S, Madshus IH, Sandvig K (1990)
Protein toxins with intracellular targets
Microb Pathog, 8 (3), 163-8
DOI 10.1016/0882-4010(90)90043-p, PubMed 1696341
Paprocka M, Wiedlocha A, Radzikowski C (1990)
Mouse L1210V leukemia as a model to analyse efficiency of leukemic cell elimination by immunotoxin, antibody and complement, and cytostatic agents
In Vivo, 4 (3), 209-13
PubMed 2133264
Tønnessen TI, Sandvig K, Olsnes S (1990)
Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality
Am J Physiol, 258 (6 Pt 1), C1117-26
DOI 10.1152/ajpcell.1990.258.6.C1117, PubMed 2163200
Tønnessen TI, Aas AT, Ludt J, Blomhoff HK, Olsnes S (1990)
Regulation of Na+/H+ and Cl-/HCO3- antiports in Vero cells
J Cell Physiol, 143 (1), 178-87
DOI 10.1002/jcp.1041430125, PubMed 2156872

Publications 1989

Hansen SH, Petersen OW, Sandvig K, Olsnes S, van Deurs B (1989)
Internalized ricin and the plasma membrane glycoprotein MAM-6 colocalize in the trans-Golgi network of T47D human breast carcinoma cells
Exp Cell Res, 185 (2), 373-86
DOI 10.1016/0014-4827(89)90307-8, PubMed 2689197
Katnik I, Steuden I, Pupek M, Wiedłocha A, Dobryszycka W (1989)
Monoclonal antibodies against human haptoglobin
Hybridoma, 8 (5), 551-60
DOI 10.1089/hyb.1989.8.551, PubMed 2478448
McGill S, Stenmark H, Sandvig K, Olsnes S (1989)
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants
EMBO J, 8 (10), 2843-8
DOI 10.1002/j.1460-2075.1989.tb08431.x, PubMed 2684631
Moskaug JO, Sandvig K, Olsnes S (1989)
Role of anions in low pH-induced translocation of diphtheria toxin
J Biol Chem, 264 (19), 11367-72
PubMed 2500440
Moskaug JO, Sletten K, Sandvig K, Olsnes S (1989)
Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage
J Biol Chem, 264 (26), 15709-13
PubMed 2768283
Olsnes S, Sandvig K, Petersen OW, van Deurs B (1989)
Immunotoxins--entry into cells and mechanisms of action
Immunol Today, 10 (9), 291-5
PubMed 2686677
Olsnes S, Stenmark H, McGill S, Hovig E, Collier RJ, Sandvig K (1989)
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
J Biol Chem, 264 (22), 12747-51
PubMed 2753882
OLSNES S, STENMARK H, MCGILL S, HOVIG E, COLLIER RJ, SANDVIG K (1989)
FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
J. Biol. Chem., 264 (22), 12749-12751
Radzikowski CZ, Steuden I, Wiedlocha A, Kieler J, Tromholt V (1989)
The Thomsen-Friedenreich antigen on human urothelial cell lines detectable by peanut lectin and monoclonal antibody raised against human glycophorin A
Anticancer Res, 9 (1), 103-7
PubMed 2650614
Sandvig K, Olsnes S, Brown JE, Petersen OW, van Deurs B (1989)
Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1
J Cell Biol, 108 (4), 1331-43
DOI 10.1083/jcb.108.4.1331, PubMed 2564398
Sandvig K, Olsnes S, Petersen OW, Van Deurs B (1989)
Control of coated-pit function by cytoplasmic pH
Methods Cell Biol, 32, 365-82
DOI 10.1016/s0091-679x(08)61181-4, PubMed 2575206
Stenmark H, McGill S, Olsnes S, Sandvig K (1989)
Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
EMBO J, 8 (10), 2849-53
DOI 10.1002/j.1460-2075.1989.tb08432.x, PubMed 2479538
Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport
J Pharmacol Exp Ther, 248 (3), 1197-206
PubMed 2703970
Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Inhibition of chloride/bicarbonate antiports in monkey kidney cells (Vero) by non-steroidal anti-inflammatory drugs
Biochem Pharmacol, 38 (20), 3583-91
DOI 10.1016/0006-2952(89)90131-7, PubMed 2818647
van Deurs B, Petersen OW, Olsnes S, Sandvig K (1989)
The ways of endocytosis
Int Rev Cytol, 117, 131-77
DOI 10.1016/s0074-7696(08)61336-4, PubMed 2573583
van Deurs B, Petersen OW, Sandvig K, Olsnes S (1989)
[Endocytosis, intracellular transport and sorting of proteins]
Nord Med, 104 (1), 9-11
PubMed 2911460

Publications 1988

Czerwiński M, Waśniowska K, Steuden I, Duk M, Wiedłocha A, Lisowska E (1988)
Degradation of the human erythrocyte membrane band 3 studied with monoclonal antibody directed against an epitope on the cytoplasmic fragment of band 3
Eur J Biochem, 174 (4), 647-54
DOI 10.1111/j.1432-1033.1988.tb14147.x, PubMed 2455637
Holtskog R, Sandvig K, Olsnes S (1988)
Characterization of a toxic lectin in Iscador, a mistletoe preparation with alleged cancerostatic properties
Oncology, 45 (3), 172-9
DOI 10.1159/000226557, PubMed 3368193
Moskaug JO, Sandvig K, Olsnes S (1988)
Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol
J Biol Chem, 263 (5), 2518-25
PubMed 3339019
Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1988)
Diphtheria toxin entry: protein translocation in the reverse direction
Trends Biochem Sci, 13 (9), 348-51
DOI 10.1016/0968-0004(88)90105-3, PubMed 3072713
Olsnes S, Sandvig K (1988)
How protein toxins enter and kill cells
Cancer Treat Res, 37, 39-73
DOI 10.1007/978-1-4613-1083-9_4, PubMed 2908634
Reinertsen KV, Tønnessen TI, Jacobsen J, Sandvig K, Olsnes S (1988)
Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport
J Biol Chem, 263 (23), 11117-25
PubMed 3403517
Sandvig K, Olsnes S (1988)
Diphtheria toxin-induced channels in Vero cells selective for monovalent cations
J Biol Chem, 263 (25), 12352-9
PubMed 2457582
Sandvig K, Olsnes S, Petersen OW, van Deurs B (1988)
Inhibition of endocytosis from coated pits by acidification of the cytosol
J Cell Biochem, 36 (1), 73-81
DOI 10.1002/jcb.240360108, PubMed 2893802
Stenmark H, Olsnes S, Sandvig K (1988)
Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
J Biol Chem, 263 (26), 13449-55
PubMed 3417666
van Deurs B, Sandvig K, Petersen OW, Olsnes S, Simons K, Griffiths G (1988)
Estimation of the amount of internalized ricin that reaches the trans-Golgi network
J Cell Biol, 106 (2), 253-67
DOI 10.1083/jcb.106.2.253, PubMed 2892843
Waśniowska K, Duk M, Steuden I, Czerwiński M, Wiedłocha A, Lisowska E (1988)
Two monoclonal antibodies recognizing different epitopes of blood group N antigen
Arch Immunol Ther Exp (Warsz), 36 (5), 623-32
PubMed 2478103

Publications 1987

Madshus IH, Olsnes S (1987)
Selective inhibition of sodium-linked and sodium-independent bicarbonate/chloride antiport in Vero cells
J Biol Chem, 262 (16), 7486-91
PubMed 3584123
Madshus IH, Sandvig K, Olsnes S, van Deurs B (1987)
Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses
J Cell Physiol, 131 (1), 14-22
DOI 10.1002/jcp.1041310104, PubMed 3032992
Madshus IH, Tønnessen TI, Olsnes S, Sandvig K (1987)
Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
J Cell Physiol, 131 (1), 6-13
DOI 10.1002/jcp.1041310103, PubMed 3571337
Moskaug JO, Sandvig K, Olsnes S (1987)
Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH
J Biol Chem, 262 (21), 10339-45
PubMed 3112141
Olsnes S (1987)
Closing in on ricin action
Nature, 328 (6130), 474-5
DOI 10.1038/328474b0, PubMed 3614350
Olsnes S, Ludt J, Tønnessen TI, Sandvig K (1987)
Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
J Cell Physiol, 132 (2), 192-202
DOI 10.1002/jcp.1041320203, PubMed 3624315
Olsnes S, Tønnessen TI, Ludt J, Sandvig K (1987)
Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
Biochemistry, 26 (10), 2778-85
DOI 10.1021/bi00384a019, PubMed 3606992
Sandvig K, Olsnes S, Petersen OW, van Deurs B (1987)
Acidification of the cytosol inhibits endocytosis from coated pits
J Cell Biol, 105 (2), 679-89
DOI 10.1083/jcb.105.2.679, PubMed 2887575
Tønnessen TI, Ludt J, Sandvig K, Olsnes S (1987)
Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
J Cell Physiol, 132 (2), 183-91
DOI 10.1002/jcp.1041320202, PubMed 3624314
van Deurs B, Petersen OW, Olsnes S, Sandvig K (1987)
Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process
Exp Cell Res, 171 (1), 137-52
DOI 10.1016/0014-4827(87)90257-6, PubMed 3622628
Aarnes CM, Madshus IH, Guillemot JC, Sandvig K, Olsnes S (1987)
Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures
Exp Cell Res, 170 (2), 483-90
DOI 10.1016/0014-4827(87)90322-3, PubMed 3036553

Publications 1986

Olsnes S, Carvajal E, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate
J Biol Chem, 261 (4), 1562-9
PubMed 3632976
Olsnes S, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells
J Biol Chem, 261 (4), 1542-52
PubMed 3944100
Olsnes S, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin
J Biol Chem, 261 (4), 1553-61
PubMed 3944101
Olsnes S, Tønnessen TI, Sandvig K (1986)
pH-regulated anion antiport in nucleated mammalian cells
J Cell Biol, 102 (3), 967-71
DOI 10.1083/jcb.102.3.967, PubMed 3949885
Sandvig K, Olsnes S (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport
J Biol Chem, 261 (4), 1570-5
PubMed 2418015
SANDVIG K, TONNESSEN TI, SAND O, OLSNES S (1986)
REQUIREMENT OF A TRANSMEMBRANE PH GRADIENT FOR THE ENTRY OF DIPHTHERIA-TOXIN INTO CELLS AT LOW PH
J. Biol. Chem., 261 (25), 1639-1644
Sandvig K, Tønnessen TI, Olsnes S (1986)
Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
Cancer Res, 46 (12 Pt 1), 6418-22
PubMed 3096563
Sandvig K, Tønnessen TI, Sand O, Olsnes S (1986)
Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
J Biol Chem, 261 (25), 11639-44
PubMed 3745160
van Deurs B, Tønnessen TI, Petersen OW, Sandvig K, Olsnes S (1986)
Routing of internalized ricin and ricin conjugates to the Golgi complex
J Cell Biol, 102 (1), 37-47
DOI 10.1083/jcb.102.1.37, PubMed 3001103

Publications 1985

Guillemot JC, Sundan A, Olsnes S, Sandvig K (1985)
Entry of diphtheria toxin linked to concanavalin A into primate and murine cells
J Cell Physiol, 122 (2), 193-9
DOI 10.1002/jcp.1041220205, PubMed 3844014
Madshus IH, Sandvig K, Olsnes S (1985)
Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1
Exp Cell Res, 160 (1), 240-4
DOI 10.1016/0014-4827(85)90253-8, PubMed 2995095
Olsnes S, Carvajal E, Sundan A, Sandvig K (1985)
Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells
Biochim Biophys Acta, 846 (3), 334-41
DOI 10.1016/0167-4889(85)90003-5, PubMed 4041483
Olsnes S, Sandvig K, Madshus IH, Sundan A (1985)
Entry mechanisms of protein toxins and picornaviruses
Biochem Soc Symp, 50, 171-91
PubMed 3915869
OLSNES S, SANDVIG K, MADSHUS IH, SUNDAN A (1985)
ENTRY MECHANISMS OF PROTEIN TOXINS AND PICORNAVIRUSES
Biochem. Soc. Symp. (50), 171-191
Sandvig K, Olsnes S (1985)
Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells
Biochem J, 228 (2), 521-3
DOI 10.1042/bj2280521, PubMed 2990449
Sandvig K, Sundan A, Olsnes S (1985)
Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin
J Cell Physiol, 124 (1), 54-60
DOI 10.1002/jcp.1041240110, PubMed 3930519
Stirpe F, Barbieri L, Abbondanza A, Falasca AI, Brown AN, Sandvig K, Olsnes S, Pihl A (1985)
Properties of volkensin, a toxic lectin from Adenia volkensii
J Biol Chem, 260 (27), 14589-95
PubMed 3932357
STIRPE F, BARBIERI L, ABBONDANZA A, FALASCA AI, BROWN ANF, SANDVIG K, OLSNES S, PIHL A (1985)
PROPERTIES OF VOLKENSIN, A TOXIC LECTIN FROM ADENIA-VOLKENSII
J. Biol. Chem., 260 (27), 4589-4595
van Deurs B, Pedersen LR, Sundan A, Olsnes S, Sandvig K (1985)
Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing to vacuolar and tubulo-vesicular portions of the endosomal system
Exp Cell Res, 159 (2), 287-304
DOI 10.1016/s0014-4827(85)80003-3, PubMed 2863159

Publications 1984

Madshus IH, Olsnes S, Sandvig K (1984)
Requirements for entry of poliovirus RNA into cells at low pH
EMBO J, 3 (9), 1945-50
DOI 10.1002/j.1460-2075.1984.tb02074.x, PubMed 6092049
Madshus IH, Olsnes S, Sandvig K (1984)
Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus
Virology, 139 (2), 346-57
DOI 10.1016/0042-6822(84)90380-5, PubMed 6097029
Madshus IH, Olsnes S, Sandvig K (1984)
Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH
J Cell Biol, 98 (4), 1194-200
DOI 10.1083/jcb.98.4.1194, PubMed 6325467
Sandvig K, Madshus IH, Olsnes S (1984)
Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus
Biochem J, 219 (3), 935-40
DOI 10.1042/bj2190935, PubMed 6331401
Sandvig K, Olsnes S (1984)
Receptor-mediated entry of protein toxins into cells
Acta Histochem Suppl, 29, 79-94
PubMed 6144140
Sandvig K, Olsnes S (1984)
Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin
J Cell Physiol, 119 (1), 7-14
DOI 10.1002/jcp.1041190103, PubMed 6707104
Sandvig K, Sundan A, Olsnes S (1984)
Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments
J Cell Biol, 98 (3), 963-70
DOI 10.1083/jcb.98.3.963, PubMed 6699094
Sundan A, Sandvig K, Olsnes S (1984)
Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin
Cancer Res, 44 (11), 4919-23
PubMed 6435858
Sundan A, Sandvig K, Olsnes S (1984)
Calmodulin antagonists sensitize cells to pseudomonas toxin
J Cell Physiol, 119 (1), 15-22
DOI 10.1002/jcp.1041190104, PubMed 6707099

Publications 1983

Eiklid K, Olsnes S (1983)
Animal toxicity of Shigella dysenteriae cytotoxin: evidence that the neurotoxic, enterotoxic, and cytotoxic activities are due to one toxin
J Immunol, 130 (1), 380-4
PubMed 6336624
Eiklid K, Olsnes S (1983)
Entry of Shigella dysenteriae toxin into HeLa cells
Infect Immun, 42 (2), 771-7
DOI 10.1128/iai.42.2.771-777.1983, PubMed 6358031
Sundan A, Sandvig K, Olsnes S (1983)
Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase
Biochem Biophys Res Commun, 117 (2), 562-7
DOI 10.1016/0006-291x(83)91237-8, PubMed 6318763
Sundan A, Sandvig K, Olsnes S (1983)
Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain
Biochim Biophys Acta, 761 (3), 296-302
DOI 10.1016/0304-4165(83)90080-6, PubMed 6652111

Publications 1982

Olsnes S, Haylett T, Sandvig K (1982)
The toxic lectin modeccin
Methods Enzymol, 83, 357-62
DOI 10.1016/0076-6879(82)83030-9, PubMed 6178935
Olsnes S, Stirpe F, Sandvig K, Pihl A (1982)
Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe)
J Biol Chem, 257 (22), 13263-70
PubMed 7142144
Sandvig K, Olsnes S (1982)
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
J Biol Chem, 257 (13), 7495-503
PubMed 6806276
Sandvig K, Olsnes S (1982)
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
J Biol Chem, 257 (13), 7504-13
PubMed 7085634
Stirpe F, Sandvig K, Olsnes S, Pihl A (1982)
Action of viscumin, a toxic lectin from mistletoe, on cells in culture
J Biol Chem, 257 (22), 13271-7
PubMed 7142145
Sundan A, Olsnes S, Sandvig K, Pihl A (1982)
Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway
J Biol Chem, 257 (16), 9733-9
PubMed 7107588

Publications 1981

Godal A, Olsnes S, Pihl A (1981)
Radioimmunoassays of abrin and ricin in blood
J Toxicol Environ Health, 8 (3), 409-17
DOI 10.1080/15287398109530079, PubMed 7345165
Olsnes S (1981)
Directing toxins to cancer cells
Nature, 290 (5802), 84
DOI 10.1038/290084a0, PubMed 7207602
Olsnes S, Pihl A (1981)
Chimeric toxins
Pharmacol Ther, 15 (3), 355-81
DOI 10.1016/0163-7258(81)90050-4, PubMed 7345440
Olsnes S, Reisbig R, Eiklid K (1981)
Subunit structure of Shigella cytotoxin
J Biol Chem, 256 (16), 8732-8
PubMed 7021550
Reisbig R, Olsnes S, Eiklid K (1981)
The cytotoxic activity of Shigella toxin. Evidence for catalytic inactivation of the 60 S ribosomal subunit
J Biol Chem, 256 (16), 8739-44
PubMed 6894922
Sandvig K, Olsnes S (1981)
Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule
J Biol Chem, 256 (17), 9068-76
PubMed 7263699
Sandvig K, Olsnes S (1981)
Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin
Biochem J, 194 (3), 821-7
DOI 10.1042/bj1940821, PubMed 7306026

Publications 1980

Eiklid K, Olsnes S (1980)
Interaction of Shigella shigae cytotoxin with receptors on sensitive and insensitive cells
J Recept Res, 1 (2), 199-213
DOI 10.3109/10799898009044098, PubMed 6895387
Eiklid K, Olsnes S, Pihl A (1980)
Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells
Exp Cell Res, 126 (2), 321-6
DOI 10.1016/0014-4827(80)90270-0, PubMed 7363949
Gonatas J, Stieber A, Olsnes S, Gonatas NK (1980)
Pathways involved in fluid phase and adsorptive endocytosis in neuroblastoma
J Cell Biol, 87 (3 Pt 1), 579-88
DOI 10.1083/jcb.87.3.579, PubMed 7462317
Olsnes S, Eiklid K (1980)
Isolation and characterization of Shigella shigae cytotoxin
J Biol Chem, 255 (1), 284-9
PubMed 7350160
Sandvig K, Olsnes S (1980)
Diphtheria toxin entry into cells is facilitated by low pH
J Cell Biol, 87 (3 Pt 1), 828-32
DOI 10.1083/jcb.87.3.828, PubMed 7462324
Stirpe F, Olsnes S, Pihl A (1980)
Gelonin, a new inhibitor of protein synthesis, nontoxic to intact cells. Isolation, characterization, and preparation of cytotoxic complexes with concanavalin A
J Biol Chem, 255 (14), 6947-53
PubMed 7391060
Tveit KM, Fodstad O, Brøgger A, Olsnes S (1980)
Human embryonal carcinoma grown in athymic mice and in vitro
Cancer Res, 40 (3), 949-53
PubMed 7471109
Tveit KM, Fodstad O, Johannessen JV, Olsnes S (1980)
A human melanoma cell line established from xenograft in athymic mice
Br J Cancer, 41 (5), 724-33
DOI 10.1038/bjc.1980.134, PubMed 7426299
Tveit KM, Fodstad O, Olsnes S, Pihl A (1980)
In vitro sensitivity of human melanoma xenografts to cytotoxic drugs. Correlation with in vivo chemosensitivity
Int J Cancer, 26 (6), 717-22
DOI 10.1002/ijc.2910260604, PubMed 7216540

Publications 1979

Abraham AK, Olsnes S, Pihl A (1979)
Fidelity of protein synthesis in vitro is increased in the presence of spermidine
FEBS Lett, 101 (1), 93-6
DOI 10.1016/0014-5793(79)81302-2, PubMed 446744
Olsnes S, Abraham AK (1979)
Elongation-factor-2-induced sensitization of ribosomes to modeccin. Evidence for specific binding of elongation factor 2 to ribosomes in the absence of nucleotides
Eur J Biochem, 93 (3), 447-52
DOI 10.1111/j.1432-1033.1979.tb12842.x, PubMed 421687
Sandvig K, Olsnes S (1979)
Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells
Exp Cell Res, 121 (1), 15-25
DOI 10.1016/0014-4827(79)90439-7, PubMed 446525
Sandvig K, Olsnes S, Pihl A (1979)
Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells
Biochem Biophys Res Commun, 90 (2), 648-55
DOI 10.1016/0006-291x(79)91284-1, PubMed 508328

Publications 1978

Olsnes S (1978)
Toxic and nontoxic lectins from Abrus precatorius
Methods Enzymol, 50, 323-30
DOI 10.1016/0076-6879(78)50036-0, PubMed 661585
Olsnes S (1978)
Ricin and ricinus agglutinin, toxic lectins from castor bean
Methods Enzymol, 50, 330-5
DOI 10.1016/0076-6879(78)50037-2, PubMed 661586
Olsnes S, Haylett T, Refsnes K (1978)
Purification and characterization of the highly toxic lectin modeccin
J Biol Chem, 253 (14), 5069-73
PubMed 97288
OLSNES S, PIHL A (1978)
ABRIN AND RICIN-2 TOXIC LECTINS
Trends Biochem.Sci., 3 (1), 7-10
DOI 10.1016/S0968-0004(78)92494-5
Olsnes S, Refsnes K (1978)
On the mechanism of toxin resistance in cell variants resistant to abrin and ricin
Eur J Biochem, 88 (1), 7-15
DOI 10.1111/j.1432-1033.1978.tb12417.x, PubMed 566668
Olsnes S, Sandvig K, Eiklid K, Pihl A (1978)
Properties and action mechanism of the toxic lectin modeccin: interaction with cell lines resistant to modeccin, abrin, and ricin
J Supramol Struct, 9 (1), 15-25
DOI 10.1002/jss.400090103, PubMed 732310
Olsnes S, Tveit KM (1978)
[Teratocarcinoma as a model system in studies of malignancy and differentiation]
Tidsskr Nor Laegeforen, 98 (22), 998-1001
PubMed 684708
Sandvig K, Olsnes S, Pihl A (1978)
Interactions between abrus lectins and Sephadex particles possessing immobilized desialylated fetuin. Model studies of the interaction of lectins with cell surface receptors
Eur J Biochem, 88 (1), 307-13
DOI 10.1111/j.1432-1033.1978.tb12451.x, PubMed 78847
Sandvig K, Olsnes S, Pihl A (1978)
Binding, uptake and degradation of the toxic proteins abrin and ricin by toxin-resistant cell variants
Eur J Biochem, 82 (1), 13-23
DOI 10.1111/j.1432-1033.1978.tb11992.x, PubMed 620666
Sandvig K, Olsnes S, Pihl A (1978)
Chemical modifications of the toxic lectins abrin and ricin
Eur J Biochem, 84 (2), 323-31
DOI 10.1111/j.1432-1033.1978.tb12171.x, PubMed 639792

Publications 1977

Fodstad O, Olsnes S (1977)
Studies on the accessability of ribosomes to inactivation by the toxic lectins abrin and ricin
Eur J Biochem, 74 (2), 209-15
DOI 10.1111/j.1432-1033.1977.tb11383.x, PubMed 856578
Fodstad O, Olsnes S, Pihl A (1977)
Inhibitory effect of abrin and ricin on the growth of transplantable murine tumors and of abrin on human cancers in nude mice
Cancer Res, 37 (12), 4559-67
PubMed 922739
Refsnes K, Haylett T, Sandvig K, Olsnes S (1977)
Modeccin--a plant toxin inhibiting protein synthesis
Biochem Biophys Res Commun, 79 (4), 1176-83
DOI 10.1016/0006-291x(77)91130-5, PubMed 603653
Skorve J, Abraham AK, Olsnes S, Pihl A (1977)
Effect of abrin on peptide chain initiation
Eur J Biochem, 79 (2), 559-64
DOI 10.1111/j.1432-1033.1977.tb11840.x, PubMed 243461

Publications 1976

Fernandez-Puentes C, Benson S, Olsnes S, Pihl A (1976)
Protective effect of elongation factor 2 on the inactivation of ribosomes by the toxic lectins abrin and ricin
Eur J Biochem, 64 (2), 437-43
DOI 10.1111/j.1432-1033.1976.tb10320.x, PubMed 1278169
Fodstad O, Olsnes S, Pihl A (1976)
Toxicity, distribution and elimination of the cancerostatic lectins abrin and ricin after parenteral injection into mice
Br J Cancer, 34 (4), 418-25
DOI 10.1038/bjc.1976.187, PubMed 974006
OLSNES S (1976)
ABRIN AND RICIN - STRUCTURE AND MECHANISM OF ACTION OF 2 TOXIC LECTINS
Bull. Inst. Pasteur, 74 (1), 85-99
Olsnes S, Sandvig K, Refsnes K, Pihl A (1976)
Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin
J Biol Chem, 251 (13), 3985-92
PubMed 932017
Sandvig K, Olsnes S, Pihl A (1976)
Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells
J Biol Chem, 251 (13), 3977-84
PubMed 6468

Publications 1975

Benson S, Olsnes S, Pihl A, Skorve J, Abraham AK (1975)
On the mechanism of protein-synthesis inhibition by abrin and ricin. Inhibition of the GTP-hydrolysis site on the 60-S ribosomal subunit
Eur J Biochem, 59 (2), 573-80
DOI 10.1111/j.1432-1033.1975.tb02484.x, PubMed 128455
Closs O, Saltvedt E, Olsnes S (1975)
Stimulation of human lymphocytes by galactose-specific abrus and ricinus lectins
J Immunol, 115 (4), 1045-8
PubMed 1176765
HARBOE M, SALTVEDT E, CLOSS O, OLSNES S (1975)
INTERACTIONS BETWEEN RICINUS AGGLUTININ AND HUMAN PLASMA-PROTEINS
Scand. J. Immunol. (2), 125-134
Kozlov JV, Olsnes S, Brogger A, Pihl A (1975)
Cleavage of adenovirus-5 DNA by an endonuclease from Haemophilus parainfluenzae
FEBS Lett, 57 (2), 153-7
DOI 10.1016/0014-5793(75)80705-8, PubMed 1175785
Olsnes S, Fernandez-Puentes C, Carrasco L, Vazquez D (1975)
Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains
Eur J Biochem, 60 (1), 281-8
DOI 10.1111/j.1432-1033.1975.tb21001.x, PubMed 1204642
Olsnes S, Refsnes K, Christensen TB, Pihl A (1975)
Studies on the structure and properties of the lectins from Abrus precatorius and Ricinus communis
Biochim Biophys Acta, 405 (1), 1-10
DOI 10.1016/0005-2795(75)90308-6, PubMed 1174560
Olsnes S, Saltvedt E (1975)
Conformation-dependent antigenic determinants in the toxic lectin ricin
J Immunol, 114 (6), 1743-8
PubMed 47877
Saltvedt E, Harboe M, Følling I, Olsnes S (1975)
Interactions between ricinus agglutinin and human IgM and IgG
Scand J Immunol, 4 (3), 287-94
DOI 10.1111/j.1365-3083.1975.tb02628.x, PubMed 1080291

Publications 1974

Olsnes S, Pappenheimer AM, Meren R (1974)
Lectins from Abrus precatorius and Ricinus communis. II. Hybrid toxins and their interaction with chain-specific antibodies
J Immunol, 113 (3), 842-7
PubMed 4414071
Olsnes S, Pihl A (1974)
Clinical significance of estrogen receptors in human breast cancer
Biomedicine, 20 (6), 377-83
PubMed 4376029
Olsnes S, Refsnes K, Pihl A (1974)
Mechanism of action of the toxic lectins abrin and ricin
Nature, 249 (458), 627-31
DOI 10.1038/249627a0, PubMed 4857870
Olsnes S, Saltvedt E, Pihl A (1974)
Isolation and comparison of galactose-binding lectins from Abrus precatorius and Ricinus communis
J Biol Chem, 249 (3), 803-10
PubMed 4811904
Pappenheimer AM, Olsnes S, Harper AA (1974)
Lectins from Abrus precatorius and Ricinus communis. I. Immunochemical relationships between toxins and agglutinins
J Immunol, 113 (3), 835-41
PubMed 4213214
Refsnes K, Olsnes S, Pihl A (1974)
On the toxic proteins abrin and ricin. Studies of their binding to and entry into Ehrlich ascites cells
J Biol Chem, 249 (11), 3557-62
PubMed 4208663
REFSNES K, OLSNES S, PIHL A (1974)
TOXIC PROTEINS ABRIN AND RICIN - STUDIES OF THEIR BINDING TO AND ENTRY INTO EHRLICH ASCITES-CELLS
J. Biol. Chem., 249 (11), 3557-3562

Publications 1973

Olsnes S (1973)
[Gene activation and mRNA synthesis in higher organisms]
Tidsskr Nor Laegeforen, 93 (16), 1230-5
PubMed 4356591
Olsnes S (1973)
[Diphtheria toxin--a specific inhibitor of protein synthesis]
Tidsskr Nor Laegeforen, 93 (4), 223-7
PubMed 4691026
Olsnes S, Heiberg R, Pihl A (1973)
Inactivation of eucaryotic ribosomes by the toxic plant proteins abrin and ricin
Mol Biol Rep, 1 (1), 15-20
DOI 10.1007/BF00357400, PubMed 24197425
Olsnes S, Pihl A (1973)
Isolation and properties of abrin: a toxic protein inhibiting protein synthesis. Evidence for different biological functions of its two constituent-peptide chains
Eur J Biochem, 35 (1), 179-85
DOI 10.1111/j.1432-1033.1973.tb02823.x, PubMed 4123356
Olsnes S, Pihl A (1973)
Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis
Biochemistry, 12 (16), 3121-6
DOI 10.1021/bi00740a028, PubMed 4730499
Spaeren U, Olsnes S, Brennhovd I, Efskind J, Pihl A (1973)
Content of estrogen receptors in human breast cancer
Eur J Cancer (1965), 9 (5), 353-7
DOI 10.1016/0014-2964(73)90050-9, PubMed 4355726

Publications 1972

Birkeland H, Bottolfsen K (1972)
[Iridocyclitis with juvenile rheumatoid arthritis]
Tidsskr Nor Laegeforen, 12 (13), 922-3
PubMed 5063957
Heiberg R, Spaeren U, Olsnes S, Pihl A (1972)
Binding of rat liver ribosomes to nuclear complementary RNA
Biochim Biophys Acta, 281 (2), 270-6
DOI 10.1016/0005-2787(72)90179-7, PubMed 4629425
Lukanidin EM, Olsnes S, Pihl A (1972)
Antigenic difference between informofers and protein bound to polyribosomal mRNA from rat liver
Nat New Biol, 240 (98), 90-2
DOI 10.1038/newbio240090a0, PubMed 4117892
Olsnes S (1972)
Toxic proteins inhibiting protein synthesis
Naturwissenschaften, 59 (11), 497-502
DOI 10.1007/BF00609814, PubMed 4657651
Olsnes S, Heiberg R, Pihl A (1972)
Deoxycholate-induced release of monosomes from rat liver polyribosomes
Biochim Biophys Acta, 272 (1), 75-80
DOI 10.1016/0005-2787(72)90035-4, PubMed 5043716
Olsnes S, Pihl A (1972)
Inhibition of peptide chain elongation
Nature, 238 (5365), 459-61
DOI 10.1038/238459a0, PubMed 4561855
Olsnes S, Pihl A (1972)
Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free system
FEBS Lett, 28 (1), 48-50
DOI 10.1016/0014-5793(72)80674-4, PubMed 4646874
Olsnes S, Pihl A (1972)
Possible function of the protein bound to nuclear complementary RNA
FEBS Lett, 20 (2), 181-183
DOI 10.1016/0014-5793(72)80788-9, PubMed 11946410
Olsnes S, Pihl A (1972)
Ricin - a potent inhibitor of protein synthesis
FEBS Lett, 20 (3), 327-329
DOI 10.1016/0014-5793(72)80098-x, PubMed 11946449
Olsnes S, Spaeren U, Heiberg R, Pihl A (1972)
Protein synthesis in the presence of non-ionic detergents in a cell-free system from rabbit reticulocytes
Biochem J, 130 (1), 297-9
DOI 10.1042/bj1300297, PubMed 4655435
Spaeren U, Olsnes S, Pihl A (1972)
Translation of mouse globin mRNA by isolated ribosomal subunits from rabbit reticulocytes
Biochim Biophys Acta, 272 (4), 663-6
DOI 10.1016/0005-2787(72)90525-4, PubMed 5050924

Publications 1971

Heiberg R, Olsnes S, Pihl A (1971)
On the mechanism of the inhibiting effect of aurin tricarboxylic acid on the binding of ribosomes to ribonucleic acids
FEBS Lett, 18 (1), 169-171
DOI 10.1016/0014-5793(71)80436-2, PubMed 11946112
Olsnes S (1971)
Further studies on the protein bound to the messenger RNA in mammalian polysomes
Eur J Biochem, 23 (3), 557-63
DOI 10.1111/j.1432-1033.1971.tb01654.x, PubMed 5003111
Olsnes S (1971)
Evidence that protein is bound to the rapidly labelled RNA in polyribosomes in vivo
Eur J Biochem, 23 (2), 248-52
DOI 10.1111/j.1432-1033.1971.tb01615.x, PubMed 5003205
Olsnes S (1971)
Characterization of the complex containing rapidly labelled RNA in EDTA-treated polyribosomes from rat liver
Eur J Biochem, 18 (2), 242-51
DOI 10.1111/j.1432-1033.1971.tb01237.x, PubMed 5541508
Olsnes S (1971)
The isolation of polysomes from rat liver. Contamination by membrane proteins with high affinity to ribosomes
Biochim Biophys Acta, 232 (4), 705-16
PubMed 5556851

Publications 1970

Olsnes S (1970)
Characterization of protein bound to rapidly-labelled RNA in polyribosomes from rat liver
Eur J Biochem, 15 (3), 464-71
DOI 10.1111/j.1432-1033.1970.tb01029.x, PubMed 4989503
Olsnes S (1970)
The isolation of polysomes from rat liver. Contamination of polysomes by ribonucleoprotein of nuclear origin
Biochim Biophys Acta, 213 (1), 149-58
DOI 10.1016/0005-2787(70)90016-x, PubMed 4992322
Olsnes S (1970)
Removal of structural proteins from ribosomes by treatment with sodium deoxycholate in the presence of EDTA
FEBS Lett, 7 (3), 211-213
DOI 10.1016/0014-5793(70)80162-4, PubMed 11947473

Publications 1968

Olsnes S, Hauge JG (1968)
Amino acid control of RNA synthesis in T4-infected Escherichia coli
Eur J Biochem, 7 (1), 128-36
DOI 10.1111/j.1432-1033.1968.tb19583.x, PubMed 4884582

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