Publications 2024

Hamid MHBA, Cespedes PF, Jin C, Chen JL, Gileadi U, Antoun E, Liang Z, Gao F, Teague R, Manoharan N, Maldonado-Perez D, Khalid-Alham N, Cerundolo L, Ciaoca R, Hester SS, Pinto-Fernández A, Draganov SD, Vendrell I, Liu G, Yao X, Kvalvaag A, Dominey-Foy DCC, Nanayakkara C, Kanellakis N, Chen YL et al. (2024)
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity
Nat Immunol, 25 (5), 834-846
DOI 10.1038/s41590-024-01802-3, PubMed 38561495

Kvalvaag A, Dustin ML (2024)
Clathrin controls bidirectional communication between T cells and antigen presenting cells
Bioessays, 46 (4), e2300230
DOI 10.1002/bies.202300230, PubMed 38412391

Philips EA, Liu J, Kvalvaag A, Mørch AM, Tocheva AS, Ng C, Liang H, Ahearn IM, Pan R, Luo CC, Leithner A, Qin Z, Zhou Y, Garcia-España A, Mor A, Littman DR, Dustin ML, Wang J, Kong XP (2024)
Transmembrane domain-driven PD-1 dimers mediate T cell inhibition
Sci Immunol, 9 (93), eade6256
DOI 10.1126/sciimmunol.ade6256, PubMed 38457513

Valsalakumari R, Pandya AD, Prasmickaite L, Kvalvaag A, Myrann AG, Åslund AKO, Kjos MS, Fontecha-Cuenca C, Haroon HB, Ribeiro ARS, Horejs-Hoeck J, Moghimi SM, Mørch Ý, Skotland T, Sandvig K, Mælandsmo GM, Iversen TG (2024)
Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
Int J Nanomedicine, 19, 3009-3029
DOI 10.2147/IJN.S450283, PubMed 38562610

Publications 2023

Capera J, Jainarayanan A, Navarro-Pérez M, Valvo S, Demetriou P, Depoil D, Estadella I, Kvalvaag A, Felce JH, Felipe A, Dustin ML (2023)
Dynamics and spatial organization of Kv1.3 at the immunological synapse of human CD4+ T cells
Biophys J, 123 (15), 2271-2281
DOI 10.1016/j.bpj.2023.08.011, PubMed 37596785

Hessvik NP, Sagini K, Romero S, Ramirez-Garrastacho M, Rodriguez M, Tutturen AEV, Kvalvaag A, Stang E, Brech A, Sandvig K, Llorente A (2023)
siRNA screening reveals that SNAP29 contributes to exosome release
Cell Mol Life Sci, 80 (7), 177
DOI 10.1007/s00018-023-04822-8, PubMed 37285022

Kvalvaag A, Valvo S, Céspedes PF, Saliba DG, Kurz E, Korobchevskaya K, Dustin ML (2023)
Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse
Proc Natl Acad Sci U S A, 120 (6), e2211368120
DOI 10.1073/pnas.2211368120, PubMed 36730202

Publications 2022

Céspedes PF, Jainarayanan A, Fernández-Messina L, Valvo S, Saliba DG, Kurz E, Kvalvaag A, Chen L, Ganskow C, Colin-York H, Fritzsche M, Peng Y, Dong T, Johnson E, Siller-Farfán JA, Dushek O, Sezgin E, Peacock B, Law A, Aubert D, Engledow S, Attar M, Hester S, Fischer R, Sánchez-Madrid F et al. (2022)
T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles
Nat Commun, 13 (1), 3460
DOI 10.1038/s41467-022-31160-3, PubMed 35710644

Publications 2021

Demetriou P, Abu-Shah E, Valvo S, McCuaig S, Mayya V, Kvalvaag A, Starkey T, Korobchevskaya K, Lee LYW, Friedrich M, Mann E, Kutuzov MA, Morotti M, Wietek N, Rada H, Yusuf S, Afrose J, Siokis A, Oxford IBD Cohort Investigators, Meyer-Hermann M, Ahmed AA, Depoil D, Dustin ML (2021)
Author Correction: A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals
Nat Immunol, 22 (1), 99
DOI 10.1038/s41590-020-00825-w, PubMed 33122852

Siokis A, Robert PA, Demetriou P, Kvalvaag A, Valvo S, Mayya V, Dustin ML, Meyer-Hermann M (2021)
Characterization of mechanisms positioning costimulatory complexes in immune synapses
iScience, 24 (10), 103100
DOI 10.1016/j.isci.2021.103100, PubMed 34622155

Publications 2020

Demetriou P, Abu-Shah E, Valvo S, McCuaig S, Mayya V, Kvalvaag A, Starkey T, Korobchevskaya K, Lee LYW, Friedrich M, Mann E, Kutuzov MA, Morotti M, Wietek N, Rada H, Yusuf S, Afrose J, Siokis A, Oxford IBD Cohort Investigators, Meyer-Hermann M, Ahmed AA, Depoil D, Dustin ML (2020)
A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals
Nat Immunol, 21 (10), 1232-1243
DOI 10.1038/s41590-020-0770-x, PubMed 32929275

Publications 2019

Saliba DG, Céspedes-Donoso PF, Bálint Š, Compeer EB, Korobchevskaya K, Valvo S, Mayya V, Kvalvaag A, Peng Y, Dong T, Tognoli ML, O'Neill E, Bonham S, Fischer R, Kessler BM, Dustin ML (2019)
Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells
Elife, 8
DOI 10.7554/eLife.47528, PubMed 31469364

Publications 2017

Ailte I, Lingelem AB, Kvalvaag AS, Kavaliauskiene S, Brech A, Koster G, Dommersnes PG, Bergan J, Skotland T, Sandvig K (2017)
Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
Traffic, 18 (3), 176-191
DOI 10.1111/tra.12468, PubMed 28067430

Simm R, Kvalvaag AS, van Deurs B, Lindbäck T, Sandvig K (2017)
Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network
Exp Cell Res, 357 (1), 67-78
DOI 10.1016/j.yexcr.2017.04.025, PubMed 28450044

Publications 2016

Ailte I, Lingelem AB, Kavaliauskiene S, Bergan J, Kvalvaag AS, Myrann AG, Skotland T, Sandvig K (2016)
Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding
Sci Rep, 6, 30336
DOI 10.1038/srep30336, PubMed 27458147

Asp N, Kvalvaag A, Sandvig K, Pust S (2016)
Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins
Oncotarget, 7 (18), 25443-60
DOI 10.18632/oncotarget.8327, PubMed 27029001

Publications 2014

Kvalvaag AS, Pust S, Sandvig K (2014)
Vps11, a subunit of the tethering complexes HOPS and CORVET, is involved in regulation of glycolipid degradation and retrograde toxin transport
Commun Integr Biol, 7 (1), e28129
DOI 10.4161/cib.28129, PubMed 24778763

Publications 2013

Kvalvaag AS, Pust S, Sundet KI, Engedal N, Simm R, Sandvig K (2013)
The ERM proteins ezrin and moesin regulate retrograde Shiga toxin transport
Traffic, 14 (7), 839-52
DOI 10.1111/tra.12077, PubMed 23593995