Our group studies breast tumor initiation and progression; from the cell of origin in which the first oncogenic events take place, the specific pathways and processes that are deregulated in the further progression of the tumors, to the specific events that are essential for the transition from in situ to invasive cancer. We use patient cohorts and animal models (transgenic and patient-derived xenograft - PDX). We apply high-throughput genomic technologies, functional assays, lineage-tracing, in situ hybridization techniques and statistical and bioinformatics methods in our research.
Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler
Cancers (Basel), 13 (17)
Multi-Omics Marker Analysis Enables Early Prediction of Breast Tumor Progression
Front Genet, 12, 670749
Can breast cancer be stopped? Modifiable risk factors of breast cancer among women with a prior benign or premalignant lesion
Int J Cancer, 149 (6), 1247-1256