Publications 2024

Cun HT, Bernard L, Lande KT, Lawson BC, Nesbakken AJ, Davidson B, Lindemann K, Fellman B, Sørlie T, Soliman PT, Eriksson AGZ (2024)
Comprehensive molecular characterization of early stage grade 3 endometrioid endometrial adenocarcinoma
Gynecol Oncol, 189, 138-145
DOI 10.1016/j.ygyno.2024.07.677, PubMed 39126895

Davidson B, Teien Lande K, Nebdal D, Nesbakken AJ, Holth A, Lindemann K, Zahl Eriksson AG, Sørlie T (2024)
Endometrial carcinomas with ambiguous histology often harbor TP53 mutations
Virchows Arch (in press)
DOI 10.1007/s00428-024-03912-7, PubMed 39235515

Moragas N, Fernandez-Nogueira P, Recalde-Percaz L, Inman JL, López-Plana A, Bergholtz H, Noguera-Castells A, Del Burgo PJ, Chen X, Sorlie T, Gascón P, Bragado P, Bissell M, Carbó N, Fuster G (2024)
The SEMA3F-NRP1/NRP2 axis is a key factor in the acquisition of invasive traits in in situ breast ductal carcinoma
Breast Cancer Res, 26 (1), 122
DOI 10.1186/s13058-024-01871-0, PubMed 39138514

Ohnstad HO, Blix ES, Akslen LA, Gilje B, Raj SX, Skjerven H, Borgen E, Janssen EAM, Mortensen E, Brekke MB, Falk RS, Schlichting E, Boge B, Songe-Møller S, Olsson P, Heie A, Mannsåker B, Vestlid MA, Kursetgjerde T, Gravdehaug B, Suhrke P, Sanchez E, Bublevic J, Røe OD, Geitvik GA et al. (2024)
Impact of Prosigna test on adjuvant treatment decision in lymph node-negative early breast cancer-a prospective national multicentre study (EMIT-1)
ESMO Open, 9 (6), 103475
DOI 10.1016/j.esmoop.2024.103475, PubMed 38838499

Publications 2023

Haugen MH, von der Lippe Gythfeldt H, Egeland EV, Svartdal Normann L, Pandya AD, Vedin LL, Juell S, Tenstad E, Øy GF, Kristian A, Marangoni E, Sørlie T, Steffensen K, Maelandsmo GM, Engebraaten O (2023)
Liver X receptors induce antiproliferative effects in basal-like breast cancer
Mol Oncol, 17 (10), 2041-2055
DOI 10.1002/1878-0261.13476, PubMed 37341140

Połeć A, Ekstrøm PO, Fougner C, Sørlie T, Norum JH (2023)
Rapid assessment of 3-dimensional intra-tumor heterogeneity through cycling temperature capillary electrophoresis
BMC Res Notes, 16 (1), 167
DOI 10.1186/s13104-023-06437-5, PubMed 37568187

van Amerongen R, Bentires-Alj M, van Boxtel AL, Clarke RB, Fre S, Suarez EG, Iggo R, Jechlinger M, Jonkers J, Mikkola ML, Koledova ZS, Sørlie T, Vivanco MD (2023)
Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research
J Mammary Gland Biol Neoplasia, 28 (1), 17
DOI 10.1007/s10911-023-09544-y, PubMed 37450065

Publications 2022

Bergholtz H, Lien T, Lingaas F, Sørlie T (2022)
Comparative analysis of the molecular subtype landscape in canine and human mammary gland tumors
J Mammary Gland Biol Neoplasia, 27 (2), 171-183
DOI 10.1007/s10911-022-09523-9, PubMed 35932380

Langille E, Al-Zahrani KN, Ma Z, Liang M, Uuskula-Reimand L, Espin R, Teng K, Malik A, Bergholtz H, Ghamrasni SE, Afiuni-Zadeh S, Tsai R, Alvi S, Elia A, Lü Y, Oh RH, Kozma KJ, Trcka D, Narimatsu M, Liu JC, Nguyen T, Barutcu S, Loganathan SK, Bremner R, Bader GD et al. (2022)
Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer
Cancer Discov, 12 (12), 2930-2953
DOI 10.1158/2159-8290.CD-21-0865, PubMed 36108220

Staaf J, Häkkinen J, Hegardt C, Saal LH, Kimbung S, Hedenfalk I, Lien T, Sørlie T, Naume B, Russnes H, Marcone R, Ayyanan A, Brisken C, Malterling RR, Asking B, Olofsson H, Lindman H, Bendahl PO, Ehinger A, Larsson C, Loman N, Rydén L, Malmberg M, Borg Å, Vallon-Christersson J (2022)
RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer
NPJ Breast Cancer, 8 (1), 94
DOI 10.1038/s41523-022-00465-3, PubMed 35974007

Publications 2021

Bergholtz H, Carter JM, Cesano A, Cheang MCU, Church SE, Divakar P, Fuhrman CA, Goel S, Gong J, Guerriero JL, Hoang ML, Hwang ES, Kuasne H, Lee J, Liang Y, Mittendorf EA, Perez J, Prat A, Pusztai L, Reeves JW, Riazalhosseini Y, Richer JK, Sahin Ö, Sato H, Schlam I et al. (2021)
Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx^® Digital Spatial Profiler
Cancers (Basel), 13 (17)
DOI 10.3390/cancers13174456, PubMed 34503266

Lien TG, Ohnstad HO, Lingjærde OC, Vallon-Christersson J, Aaserud M, Sveli MAT, Borg Å, Osbreac OBO, Garred Ø, Borgen E, Naume B, Russnes H, Sørlie T (2021)
Sample Preparation Approach Influences PAM50 Risk of Recurrence Score in Early Breast Cancer
Cancers (Basel), 13 (23)
DOI 10.3390/cancers13236118, PubMed 34885228

Lilleborge M, Falk RS, Sørlie T, Ursin G, Hofvind S (2021)
Can breast cancer be stopped? Modifiable risk factors of breast cancer among women with a prior benign or premalignant lesion
Int J Cancer, 149 (6), 1247-1256
DOI 10.1002/ijc.33680, PubMed 33990967

Xu H, Lien T, Bergholtz H, Fleischer T, Djerroudi L, Vincent-Salomon A, Sørlie T, Aittokallio T (2021)
Multi-Omics Marker Analysis Enables Early Prediction of Breast Tumor Progression
Front Genet, 12, 670749
DOI 10.3389/fgene.2021.670749, PubMed 34149812

Publications 2020

Bergholtz H, Kumar S, Wärnberg F, Lüders T, Kristensen V, Sørlie T (2020)
Comparable cancer-relevant mutation profiles in synchronous ductal carcinoma in situ and invasive breast cancer
Cancer Rep (Hoboken), 3 (3), e1248
DOI 10.1002/cnr2.1248, PubMed 32671987

Bergholtz H, Lien TG, Swanson DM, Frigessi A, Oslo Breast Cancer Research Consortium (OSBREAC), Daidone MG, Tost J, Wärnberg F, Sørlie T (2020)
Contrasting DCIS and invasive breast cancer by subtype suggests basal-like DCIS as distinct lesions
NPJ Breast Cancer, 6, 26
DOI 10.1038/s41523-020-0167-x, PubMed 32577501

Engelsen AST, Wnuk-Lipinska K, Bougnaud S, Pelissier Vatter FA, Tiron C, Villadsen R, Miyano M, Lotsberg ML, Madeleine N, Panahandeh P, Dhakal S, Tan TZ, Peters SD, Grøndal S, Aziz SM, Nord S, Herfindal L, Stampfer MR, Sørlie T, Brekken RA, Straume O, Halberg N, Gausdal G, Thiery JP, Akslen LA et al. (2020)
AXL Is a Driver of Stemness in Normal Mammary Gland and Breast Cancer
iScience, 23 (11), 101649
DOI 10.1016/j.isci.2020.101649, PubMed 33103086

Fougner C, Bergholtz H, Norum JH, Sørlie T (2020)
Re-definition of claudin-low as a breast cancer phenotype
Nat Commun, 11 (1), 1787
DOI 10.1038/s41467-020-15574-5, PubMed 32286297

Knutsen E, Lellahi SM, Aure MR, Nord S, Fismen S, Larsen KB, Gabriel MT, Hedberg A, Bjørklund SS, Oslo Breast Cancer Research Consortium (OSBREAC), Bofin AM, Mælandsmo GM, Sørlie T, Mortensen ES, Perander M (2020)
The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers
Sci Rep, 10 (1), 1277
DOI 10.1038/s41598-020-57759-4, PubMed 31992741

Publications 2019

Bergholtz H, Lien TG, Ursin G, Holmen MM, Helland Å, Sørlie T, Haakensen VD (2019)
A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue
J Mammary Gland Biol Neoplasia, 24 (2), 163-175
DOI 10.1007/s10911-018-09423-x, PubMed 30613869

Fougner C, Bergholtz H, Kuiper R, Norum JH, Sørlie T (2019)
Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers
Breast Cancer Res, 21 (1), 85
DOI 10.1186/s13058-019-1170-8, PubMed 31366361

Norum JH, Frings O, Kasper M, Bergholtz H, Zell Thime H, Bergström Å, Andersson A, Kuiper R, Fredlund E, Sørlie T, Toftgård R (2019)
GLI1-induced mammary gland tumours are transplantable and maintain major molecular features
Int J Cancer, 146 (4), 1125-1138
DOI 10.1002/ijc.32522, PubMed 31219615

Swanson DM, Lien T, Bergholtz H, Sørlie T, Frigessi A (2019)
A Bayesian two-way latent structure model for genomic data integration reveals few pan-genomic cluster subtypes in a breast cancer cohort
Bioinformatics, 35 (23), 4886-4897
DOI 10.1093/bioinformatics/btz381, PubMed 31077301

Tekpli X, Lien T, Røssevold AH, Nebdal D, Borgen E, Ohnstad HO, Kyte JA, Vallon-Christersson J, Fongaard M, Due EU, Svartdal LG, Sveli MAT, Garred Ø, OSBREAC, Frigessi A, Sahlberg KK, Sørlie T, Russnes HG, Naume B, Kristensen VN (2019)
An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
Nat Commun, 10 (1), 5499
DOI 10.1038/s41467-019-13329-5, PubMed 31796750

Publications 2018

Norum JH, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, Sørlie T (2018)
The tankyrase inhibitor G007-LK inhibits small intestine LGR5⁺ stem cell proliferation without altering tissue morphology
Biol Res, 51 (1), 3
DOI 10.1186/s40659-017-0151-6, PubMed 29316982

Publications 2017

Gil Del Alcazar CR, Huh SJ, Ekram MB, Trinh A, Liu LL, Beca F, Zi X, Kwak M, Bergholtz H, Su Y, Ding L, Russnes HG, Richardson AL, Babski K, Min Hui Kim E, McDonnell CH, Wagner J, Rowberry R, Freeman GJ, Dillon D, Sorlie T, Coussens LM, Garber JE, Fan R, Bobolis K et al. (2017)
Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition
Cancer Discov, 7 (10), 1098-1115
DOI 10.1158/2159-8290.CD-17-0222, PubMed 28652380

Laurberg T, Tramm T, Nielsen T, Alsner J, Nord S, Myhre S, Sørlie T, Leung S, Fan C, Perou C, Gelmon K, Overgaard J, Voduc D, Prat A, Cheang MCU (2017)
Intrinsic subtypes and benefit from postmastectomy radiotherapy in node-positive premenopausal breast cancer patients who received adjuvant chemotherapy - results from two independent randomized trials
Acta Oncol, 57 (1), 38-43
DOI 10.1080/0284186X.2017.1401735, PubMed 29172851

Ohnstad HO, Borgen E, Falk RS, Lien TG, Aaserud M, Sveli MAT, Kyte JA, Kristensen VN, Geitvik GA, Schlichting E, Wist EA, Sørlie T, Russnes HG, Naume B (2017)
Prognostic value of PAM50 and risk of recurrence score in patients with early-stage breast cancer with long-term follow-up
Breast Cancer Res, 19 (1), 120
DOI 10.1186/s13058-017-0911-9, PubMed 29137653

Publications 2016

Lesurf R, Aure MR, Mørk HH, Vitelli V, Oslo Breast Cancer Research Consortium (OSBREAC), Lundgren S, Børresen-Dale AL, Kristensen V, Wärnberg F, Hallett M, Sørlie T (2016)
Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer
Cell Rep, 16 (4), 1166-1179
DOI 10.1016/j.celrep.2016.06.051, PubMed 27396337

Sørlie T (2016)
The Impact of Gene Expression Patterns in Breast Cancer
Clin Chem, 62 (8), 1150-1
DOI 10.1373/clinchem.2015.253229, PubMed 27022070

Publications 2015

Borgquist S, Zhou W, Jirström K, Amini RM, Sollie T, Sørlie T, Blomqvist C, Butt S, Wärnberg F (2015)
The prognostic role of HER2 expression in ductal breast carcinoma in situ (DCIS); a population-based cohort study
BMC Cancer, 15, 468
DOI 10.1186/s12885-015-1479-3, PubMed 26062614

Norum JH, Bergström Å, Andersson AB, Kuiper RV, Hoelzl MA, Sørlie T, Toftgård R (2015)
A conditional transgenic mouse line for targeted expression of the stem cell marker LGR5
Dev Biol, 404 (2), 35-48
DOI 10.1016/j.ydbio.2015.05.002, PubMed 26003047

Potapenko IO, Lüders T, Russnes HG, Helland Å, Sørlie T, Kristensen VN, Nord S, Lingjærde OC, Børresen-Dale AL, Haakensen VD (2015)
Glycan-related gene expression signatures in breast cancer subtypes; relation to survival
Mol Oncol, 9 (4), 861-76
DOI 10.1016/j.molonc.2014.12.013, PubMed 25655580

Skrbo N, Tenstad E, Mælandsmo GM, Sørlie T, Andersen K (2015)
From autonomy to community; new perspectives on tumorigenicity and therapy resistance
Cancer Treat Rev, 41 (10), 809-13
DOI 10.1016/j.ctrv.2015.10.004, PubMed 26519005

Publications 2014

Grinde MT, Skrbo N, Moestue SA, Rødland EA, Borgan E, Kristian A, Sitter B, Bathen TF, Børresen-Dale AL, Mælandsmo GM, Engebraaten O, Sørlie T, Marangoni E, Gribbestad IS (2014)
Interplay of choline metabolites and genes in patient-derived breast cancer xenografts
Breast Cancer Res, 16 (1), R5
DOI 10.1186/bcr3597, PubMed 24447408

Norum JH, Andersen K, Sørlie T (2014)
Lessons learned from the intrinsic subtypes of breast cancer in the quest for precision therapy
Br J Surg, 101 (8), 925-38
DOI 10.1002/bjs.9562, PubMed 24849143

Skrbo N, Hjortland GO, Kristian A, Holm R, Nord S, Prasmickaite L, Engebraaten O, Mælandsmo GM, Sørlie T, Andersen K (2014)
Differential in vivo tumorigenicity of distinct subpopulations from a luminal-like breast cancer xenograft
PLoS One, 9 (11), e113278
DOI 10.1371/journal.pone.0113278, PubMed 25419568

Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2014)
Mutation screening of the TP53 gene by temporal temperature gel electrophoresis (TTGE)
Methods Mol Biol, 1105, 315-24
DOI 10.1007/978-1-62703-739-6_25, PubMed 24623239

Tramm T, Kyndi M, Myhre S, Nord S, Alsner J, Sørensen FB, Sørlie T, Overgaard J (2014)
Relationship between the prognostic and predictive value of the intrinsic subtypes and a validated gene profile predictive of loco-regional control and benefit from post-mastectomy radiotherapy in patients with high-risk breast cancer
Acta Oncol, 53 (10), 1337-46
DOI 10.3109/0284186X.2014.925580, PubMed 24957550

Tramm T, Mohammed H, Myhre S, Kyndi M, Alsner J, Børresen-Dale AL, Sørlie T, Frigessi A, Overgaard J (2014)
Development and validation of a gene profile predicting benefit of postmastectomy radiotherapy in patients with high-risk breast cancer: a study of gene expression in the DBCG82bc cohort
Clin Cancer Res, 20 (20), 5272-80
DOI 10.1158/1078-0432.CCR-14-0458, PubMed 25149560

Zhao X, Rødland EA, Sørlie T, Vollan HK, Russnes HG, Kristensen VN, Lingjærde OC, Børresen-Dale AL (2014)
Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status
BMC Cancer, 14, 211
DOI 10.1186/1471-2407-14-211, PubMed 24645668

Publications 2013

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522

Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825

Publications 2012

Borgan E, Lindholm EM, Moestue S, Mælandsmo GM, Lingjærde OC, Gribbestad IS, Børresen-Dale AL, Engebraaten O, Sørlie T (2012)
Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts
Mol Oncol, 7 (1), 130-42
DOI 10.1016/j.molonc.2012.10.005, PubMed 23142657

Guiu S, Michiels S, André F, Cortes J, Denkert C, Di Leo A, Hennessy BT, Sorlie T, Sotiriou C, Turner N, Van de Vijver M, Viale G, Loi S, Reis-Filho JS (2012)
Molecular subclasses of breast cancer: how do we define them? The IMPAKT 2012 Working Group Statement
Ann Oncol, 23 (12), 2997-3006
DOI 10.1093/annonc/mds586, PubMed 23166150

Kim J, Villadsen R, Sørlie T, Fogh L, Grønlund SZ, Fridriksdottir AJ, Kuhn I, Rank F, Wielenga VT, Solvang H, Edwards PA, Børresen-Dale AL, Rønnov-Jessen L, Bissell MJ, Petersen OW (2012)
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
Proc Natl Acad Sci U S A, 109 (16), 6124-9
DOI 10.1073/pnas.1203203109, PubMed 22454501

Nerum H, Halvorsen L, Straume B, Sørlie T, Øian P (2012)
Different labour outcomes in primiparous women that have been subjected to childhood sexual abuse or rape in adulthood: a case-control study in a clinical cohort
BJOG, 120 (4), 487-95
DOI 10.1111/1471-0528.12053, PubMed 23157417

Publications 2011

Akslen LA, Straume O, Geisler S, Sørlie T, Chi JT, Aas T, Børresen-Dale AL, Lønning PE (2011)
Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer
Br J Cancer, 105 (1), 9-12
DOI 10.1038/bjc.2011.203, PubMed 21673677

Borgan E, Navon R, Vollan HK, Schlichting E, Sauer T, Yakhini Z, Lingjærde OC, Sørlie T, Børresen-Dale AL (2011)
Ischemia caused by time to freezing induces systematic microRNA and mRNA responses in cancer tissue
Mol Oncol, 5 (6), 564-76
DOI 10.1016/j.molonc.2011.08.004, PubMed 21917534

Kristensen VN, Vaske CJ, Ursini-Siegel J, Van Loo P, Nordgard SH, Sachidanandam R, Sørlie T, Wärnberg F, Haakensen VD, Helland Å, Naume B, Perou CM, Haussler D, Troyanskaya OG, Børresen-Dale AL (2011)
Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling
Proc Natl Acad Sci U S A, 109 (8), 2802-7
DOI 10.1073/pnas.1108781108, PubMed 21908711

Sørlie T (2011)
How to personalise treatment in early breast cancer
Eur J Cancer, 47 Suppl 3, S310-1
DOI 10.1016/S0959-8049(11)70182-4, PubMed 21943994

Zhao X, Rødland EA, Sørlie T, Naume B, Langerød A, Frigessi A, Kristensen VN, Børresen-Dale AL, Lingjærde OC (2011)
Combining gene signatures improves prediction of breast cancer survival
PLoS One, 6 (3), e17845
DOI 10.1371/journal.pone.0017845, PubMed 21423775

Publications 2010

Borgan E, Sitter B, Lingjærde OC, Johnsen H, Lundgren S, Bathen TF, Sørlie T, Børresen-Dale AL, Gribbestad IS (2010)
Merging transcriptomics and metabolomics--advances in breast cancer profiling
BMC Cancer, 10, 628
DOI 10.1186/1471-2407-10-628, PubMed 21080935

Børresen-Dale AL, Sørlie T, Kristensen VN (2010)
On the molecular biology of breast cancer
Mol Oncol, 4 (3), 171-3
DOI 10.1016/j.molonc.2010.04.007, PubMed 20483673

Muggerud AA, Hallett M, Johnsen H, Kleivi K, Zhou W, Tahmasebpoor S, Amini RM, Botling J, Børresen-Dale AL, Sørlie T, Wärnberg F (2010)
Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer
Mol Oncol, 4 (4), 357-68
DOI 10.1016/j.molonc.2010.06.007, PubMed 20663721

Muggerud AA, Rønneberg JA, Wärnberg F, Botling J, Busato F, Jovanovic J, Solvang H, Bukholm I, Børresen-Dale AL, Kristensen VN, Sørlie T, Tost J (2010)
Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
Breast Cancer Res, 12 (1), R3
DOI 10.1186/bcr2466, PubMed 20056007

Myhre S, Mohammed H, Tramm T, Alsner J, Finak G, Park M, Overgaard J, Børresen-Dale AL, Frigessi A, Sørlie T (2010)
In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome
PLoS One, 5 (11), e14002
DOI 10.1371/journal.pone.0014002, PubMed 21124964

Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Stromberg M, Wiedswang G, Kvalheim G, Karesen R, Nesland JM, Borresen-Dale AL, Sorlie T (2010)
Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer (vol 1, pg 160, 2007)
Mol. Oncol., 4 (2), 169
DOI 10.1016/j.molonc.2010.01.003

Podo F, Buydens LM, Degani H, Hilhorst R, Klipp E, Gribbestad IS, Van Huffel S, van Laarhoven HW, Luts J, Monleon D, Postma GJ, Schneiderhan-Marra N, Santoro F, Wouters H, Russnes HG, Sørlie T, Tagliabue E, Børresen-Dale AL, FEMME Consortium (2010)
Triple-negative breast cancer: present challenges and new perspectives
Mol Oncol, 4 (3), 209-29
DOI 10.1016/j.molonc.2010.04.006, PubMed 20537966

Russnes HG, Vollan HKM, Lingjærde OC, Krasnitz A, Lundin P, Naume B, Sørlie T, Borgen E, Rye IH, Langerød A, Chin SF, Teschendorff AE, Stephens PJ, Månér S, Schlichting E, Baumbusch LO, Kåresen R, Stratton MP, Wigler M, Caldas C, Zetterberg A, Hicks J, Børresen-Dale AL (2010)
Genomic architecture characterizes tumor progression paths and fate in breast cancer patients
Sci Transl Med, 2 (38), 38ra47
DOI 10.1126/scitranslmed.3000611, PubMed 20592421

Sørlie T, Borgan E, Myhre S, Vollan HK, Russnes H, Zhao X, Nilsen G, Lingjaerde OC, Børresen-Dale AL, Rødland E (2010)
The importance of gene-centring microarray data
Lancet Oncol, 11 (8), 719-20; author reply 720-1
DOI 10.1016/S1470-2045(10)70174-1, PubMed 20688275

Publications 2009

Agarwal R, Gonzalez-Angulo AM, Myhre S, Carey M, Lee JS, Overgaard J, Alsner J, Stemke-Hale K, Lluch A, Neve RM, Kuo WL, Sorlie T, Sahin A, Valero V, Keyomarsi K, Gray JW, Borresen-Dale AL, Mills GB, Hennessy BT (2009)
Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer
Clin Cancer Res, 15 (11), 3654-62
DOI 10.1158/1078-0432.CCR-08-3293, PubMed 19470724

Bergamaschi A, Hjortland GO, Triulzi T, Sørlie T, Johnsen H, Ree AH, Russnes HG, Tronnes S, Maelandsmo GM, Fodstad O, Borresen-Dale AL, Engebraaten O (2009)
Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models
Mol Oncol, 3 (5-6), 469-82
DOI 10.1016/j.molonc.2009.07.003, PubMed 19713161

Muggerud AA, Edgren H, Wolf M, Kleivi K, Dejeux E, Tost J, Sørlie T, Kallioniemi O (2009)
Data integration from two microarray platforms identifies bi-allelic genetic inactivation of RIC8A in a breast cancer cell line
BMC Med Genomics, 2, 26
DOI 10.1186/1755-8794-2-26, PubMed 19432969

Potapenko IO, Haakensen VD, Lüders T, Helland A, Bukholm I, Sørlie T, Kristensen VN, Lingjaerde OC, Børresen-Dale AL (2009)
Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
Mol Oncol, 4 (2), 98-118
DOI 10.1016/j.molonc.2009.12.001, PubMed 20060370

Sørlie T (2009)
Introducing molecular subtyping of breast cancer into the clinic?
J Clin Oncol, 27 (8), 1153-4
DOI 10.1200/JCO.2008.20.6276, PubMed 19204193

Zhou W, Muggerud AA, Vu P, Due EU, Sørlie T, Børresen-Dale AL, Wärnberg F, Langerød A (2009)
Full sequencing of TP53 identifies identical mutations within in situ and invasive components in breast cancer suggesting clonal evolution
Mol Oncol, 3 (3), 214-9
DOI 10.1016/j.molonc.2009.03.001, PubMed 19403344

Publications 2008

Bergamaschi A, Tagliabue E, Sørlie T, Naume B, Triulzi T, Orlandi R, Russnes HG, Nesland JM, Tammi R, Auvinen P, Kosma VM, Ménard S, Børresen-Dale AL (2008)
Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome
J Pathol, 214 (3), 357-67
DOI 10.1002/path.2278, PubMed 18044827

Nordgard SH, Alnaes GI, Hihn B, Lingjaerde OC, Liestøl K, Tsalenko A, Sørlie T, Lønning PE, Børresen-Dale AL, Kristensen VN (2008)
Pathway based analysis of SNPs with relevance to 5-FU therapy: relation to intratumoral mRNA expression and survival
Int J Cancer, 123 (3), 577-85
DOI 10.1002/ijc.23541, PubMed 18498133

Publications 2007

Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Strømberg M, Wiedswang G, Kvalheim G, Kåresen R, Nesland JM, Børresen-Dale AL, Sørlie T (2007)
Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
Mol Oncol, 1 (2), 160-71
DOI 10.1016/j.molonc.2007.03.004, PubMed 19383292

Sørlie T (2007)
Molecular classification of breast tumors: toward improved diagnostics and treatments
Methods Mol Biol, 360, 91-114
DOI 10.1385/1-59745-165-7:91, PubMed 17172726

Publications 2006

Bergamaschi A, Kim YH, Wang P, Sørlie T, Hernandez-Boussard T, Lonning PE, Tibshirani R, Børresen-Dale AL, Pollack JR (2006)
Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer
Genes Chromosomes Cancer, 45 (11), 1033-40
DOI 10.1002/gcc.20366, PubMed 16897746

Kristensen VN, Edvardsen H, Tsalenko A, Nordgard SH, Sørlie T, Sharan R, Vailaya A, Ben-Dor A, Lønning PE, Lien S, Omholt S, Syvänen AC, Yakhini Z, Børresen-Dale AL (2006)
Genetic variation in putative regulatory loci controlling gene expression in breast cancer
Proc Natl Acad Sci U S A, 103 (20), 7735-40
DOI 10.1073/pnas.0601893103, PubMed 16684880

Muggerud AA, Johnsen H, Barnes DA, Steel A, Lønning PE, Naume B, Sørlie T, Børresen-Dale AL (2006)
Evaluation of MetriGenix custom 4D arrays applied for detection of breast cancer subtypes
BMC Cancer, 6, 59
DOI 10.1186/1471-2407-6-59, PubMed 16536878

Sørlie T, Perou CM, Fan C, Geisler S, Aas T, Nobel A, Anker G, Akslen LA, Botstein D, Børresen-Dale AL, Lønning PE (2006)
Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer
Mol Cancer Ther, 5 (11), 2914-8
DOI 10.1158/1535-7163.MCT-06-0126, PubMed 17121939

Sørlie T, Wang Y, Xiao C, Johnsen H, Naume B, Samaha RR, Børresen-Dale AL (2006)
Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms
BMC Genomics, 7, 127
DOI 10.1186/1471-2164-7-127, PubMed 16729877

Publications 2005

Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sørlie T, Dai H, He YD, van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ (2005)
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
Proc Natl Acad Sci U S A, 102 (10), 3738-43
DOI 10.1073/pnas.0409462102, PubMed 15701700

Kristensen VN, Sørlie T, Geisler J, Langerød A, Yoshimura N, Kåresen R, Harada N, Lønning PE, Børresen-Dale AL (2005)
Gene expression profiling of breast cancer in relation to estrogen receptor status and estrogen-metabolizing enzymes: clinical implications
Clin Cancer Res, 11 (2 Pt 2), 878s-83s
PubMed 15701881

Kristensen VN, Sørlie T, Geisler J, Yoshimura N, Linegjaerde OC, Glad I, Frigessi A, Harada N, Lønning PE, Børresen-Dale AL (2005)
Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer
J Steroid Biochem Mol Biol, 95 (1-5), 105-11
DOI 10.1016/j.jsbmb.2005.04.028, PubMed 16023338

Lønning PE, Sørlie T, Børresen-Dale AL (2005)
Genomics in breast cancer-therapeutic implications
Nat Clin Pract Oncol, 2 (1), 26-33
DOI 10.1038/ncponc0072, PubMed 16264853

Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2005)
Mutation screening of the TP53 gene by temporal temperature gradient gel electrophoresis
Methods Mol Biol, 291, 207-16
DOI 10.1385/1-59259-840-4:207, PubMed 15502225

Wolf M, Edgren H, Muggerud A, Kilpinen S, Huusko P, Sorlie T, Mousses S, Kallioniemi O (2005)
NMD microarray analysis for rapid genome-wide screen of mutated genes in cancer
Cell. Oncol., 27 (3), 169-173

Wolf M, Edgren H, Muggerud A, Kilpinen S, Huusko P, Sørlie T, Mousses S, Kallioniemi O (2005)
NMD microarray analysis for rapid genome-wide screen of mutated genes in cancer
Cell Oncol, 27 (3), 169-73
DOI 10.1155/2005/478316, PubMed 16037637

Publications 2004

Sørlie T (2004)
Molecular portraits of breast cancer: tumour subtypes as distinct disease entities
Eur J Cancer, 40 (18), 2667-75
DOI 10.1016/j.ejca.2004.08.021, PubMed 15571950

Sørlie T, Børresen-Dale AL, Lønning PE, Brown PO, Botstein D (2004)
Expression profiling of breast cancer: From molecular portraits to clinical utility.
In Oncogenomics: Molecular approaches to cancer (Brenner C, Duggan DJ, eds.), John Wiley & Sons, Inc., New York
PublikaID 67, ISBN 0-471-22592-4

Troester MA, Hoadley KA, Sørlie T, Herbert BS, Børresen-Dale AL, Lønning PE, Shay JW, Kaufmann WK, Perou CM (2004)
Cell-type-specific responses to chemotherapeutics in breast cancer
Cancer Res, 64 (12), 4218-26
DOI 10.1158/0008-5472.CAN-04-0107, PubMed 15205334

Publications 2003

Schaner ME, Ross DT, Ciaravino G, Sorlie T, Troyanskaya O, Diehn M, Wang YC, Duran GE, Sikic TL, Caldeira S, Skomedal H, Tu IP, Hernandez-Boussard T, Johnson SW, O'Dwyer PJ, Fero MJ, Kristensen GB, Borresen-Dale AL, Hastie T, Tibshirani R, van de Rijn M, Teng NN, Longacre TA, Botstein D, Brown PO et al. (2003)
Gene expression patterns in ovarian carcinomas
Mol Biol Cell, 14 (11), 4376-86
DOI 10.1091/mbc.e03-05-0279, PubMed 12960427

Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM, Lønning PE, Brown PO, Børresen-Dale AL, Botstein D (2003)
Repeated observation of breast tumor subtypes in independent gene expression data sets
Proc Natl Acad Sci U S A, 100 (14), 8418-23
DOI 10.1073/pnas.0932692100, PubMed 12829800

Publications 2002

Pollack JR, Sørlie T, Perou CM, Rees CA, Jeffrey SS, Lonning PE, Tibshirani R, Botstein D, Børresen-Dale AL, Brown PO (2002)
Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors
Proc Natl Acad Sci U S A, 99 (20), 12963-8
DOI 10.1073/pnas.162471999, PubMed 12297621

Publications 2001

Forus A, Sørlie T, Børresen-Dale AL, Myklebost O (2001)
[Microarray technology--potential in cancer research]
Tidsskr Nor Laegeforen, 121 (21), 2498-503
PubMed 11875927

Lønning PE, Sørlie T, Perou CM, Brown PO, Botstein D, Børresen-Dale AL (2001)
Microarrays in primary breast cancer--lessons from chemotherapy studies
Endocr Relat Cancer, 8 (3), 259-63
DOI 10.1677/erc.0.0080259, PubMed 11566617

Sørlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matese JC, Brown PO, Botstein D, Lønning PE, Børresen-Dale AL (2001)
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
Proc Natl Acad Sci U S A, 98 (19), 10869-74
DOI 10.1073/pnas.191367098, PubMed 11553815

Publications 2000

Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lønning PE, Børresen-Dale AL, Brown PO, Botstein D (2000)
Molecular portraits of human breast tumours
Nature, 406 (6797), 747-52
DOI 10.1038/35021093, PubMed 10963602

Sørlie T (2000)
Tumor genotypes and phenotypes associated with exposure, aggressiveness and clinical outcome: methodological approoaches [sic]
Department of Genetics, The Norwegian Radium Hospital, Department Group of Laboratory Medicine, Oslo, 1 b. (flere pag.)
BIBSYS 001846469, ISBN 82-7633-157-2

Publications 1999

Berner JM, Sørlie T, Mertens F, Henriksen J, Saeter G, Mandahl N, Brøgger A, Myklebost O, Lothe RA (1999)
Chromosome band 9p21 is frequently altered in malignant peripheral nerve sheath tumors: studies of CDKN2A and other genes of the pRB pathway
Genes Chromosomes Cancer, 26 (2), 151-60
DOI 10.1002/(SICI)1098-2264(199910)26:2<151::AID-GCC7>3.0.CO;2-A, PubMed 10469453

Publications 1998

Sørlie T, Andersen TI, Bukholm I, Børresen-Dale AL (1998)
Mutation screening of BRCA1 using PTT and LOH analysis at 17q21 in breast carcinomas from familial and non-familial cases
Breast Cancer Res Treat, 48 (3), 259-64
DOI 10.1023/a:1005953519972, PubMed 9598872

Sørlie T, Bukholm I, Børresen-Dale AL (1998)
Truncating somatic mutation in exon 15 of the APC gene is a rare event in human breast carcinomas. Mutations in brief no. 179. Online
Hum Mutat, 12 (3), 215
PubMed 10660330

Sørlie T, Martel-Planche G, Hainaut P, Lewalter J, Holm R, Børresen-Dale AL, Montesano R (1998)
Analysis of p53, p16MTS, p21WAF1 and H-ras in archived bladder tumours from workers exposed to aromatic amines
Br J Cancer, 77 (10), 1573-9
DOI 10.1038/bjc.1998.259, PubMed 9635831

Publications 1995

Esteve A, Sørlie T, Martel-Planche G, Hollstein M, Kusters I, Lewalter J, Vineis P, Stephan-Odenthal M, Montesano R (1995)
Screening for p53 gene mutations in archived tumors of workers occupationally exposed to carcinogens: examples from analysis of bladder tumors
J Occup Environ Med, 37 (1), 59-68
DOI 10.1097/00043764-199501000-00009, PubMed 7620944

Publications 1994

Hollstein M, Rice K, Greenblatt MS, Soussi T, Fuchs R, Sørlie T, Hovig E, Smith-Sørensen B, Montesano R, Harris CC (1994)
Database of p53 gene somatic mutations in human tumors and cell lines
Nucleic Acids Res, 22 (17), 3551-5
PubMed 7937055