Serhiy Pankiv

  • Scientist
  • +47 22 78 19 16


Publications 2022

Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
J Cell Sci, 135 (4)
DOI 10.1242/jcs.259138, PubMed 35099014

Publications 2020

Bindesbøll C, Aas A, Ogmundsdottir MH, Pankiv S, Reine T, Zoncu R, Simonsen A (2020)
NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease
Sci Rep, 10 (1), 4528
DOI 10.1038/s41598-020-61352-0, PubMed 32161285

Publications 2019

Abudu YP, Pankiv S, Mathai BJ, Lamark T, Johansen T, Simonsen A (2019)
NIPSNAP1 and NIPSNAP2 act as "eat me" signals to allow sustained recruitment of autophagy receptors during mitophagy
Autophagy, 15 (10), 1845-1847
DOI 10.1080/15548627.2019.1637642, PubMed 31251109

Princely Abudu Y, Pankiv S, Mathai BJ, Håkon Lystad A, Bindesbøll C, Brenne HB, Yoke Wui Ng M, Thiede B, Yamamoto A, Mutugi Nthiga T, Lamark T, Esguerra CV, Johansen T, Simonsen A (2019)
NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy
Dev Cell, 49 (4), 509-525.e12
DOI 10.1016/j.devcel.2019.03.013, PubMed 30982665

Publications 2018

Søreng K, Munson MJ, Lamb CA, Bjørndal GT, Pankiv S, Carlsson SR, Tooze SA, Simonsen A (2018)
SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin-2
EMBO Rep, 19 (4)
DOI 10.15252/embr.201744837, PubMed 29437695

Publications 2016

Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A (2016)
HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
Nat Commun, 7, 13889
DOI 10.1038/ncomms13889, PubMed 28004827

Publications 2014

Lystad AH, Ichimura Y, Takagi K, Yang Y, Pankiv S, Kanegae Y, Kageyama S, Suzuki M, Saito I, Mizushima T, Komatsu M, Simonsen A (2014)
Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures
EMBO Rep, 15 (5), 557-65
DOI 10.1002/embr.201338003, PubMed 24668264

Publications 2012

Lång E, Grudic A, Pankiv S, Bruserud O, Simonsen A, Bjerkvig R, Bjørås M, Bøe SO (2012)
The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling
Blood, 120 (4), 847-57
DOI 10.1182/blood-2011-10-388496, PubMed 22692509

Publications 2011

Ravuri C, Svineng G, Pankiv S, Huseby NE (2011)
Endogenous production of reactive oxygen species by the NADPH oxidase complexes is a determinant of γ-glutamyltransferase expression
Free Radic Res, 45 (5), 600-10
DOI 10.3109/10715762.2011.564164, PubMed 21381898

Publications 2010

Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A, Bjørkøy G, Johansen T (2010)
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
J Cell Biol, 188 (2), 253-69
DOI 10.1083/jcb.200907015, PubMed 20100911

Pankiv S, Johansen T (2010)
FYCO1: linking autophagosomes to microtubule plus end-directing molecular motors
Autophagy, 6 (4), 550-2
DOI 10.4161/auto.6.4.11670, PubMed 20364109

Publications 2009

Bjørkøy G, Lamark T, Pankiv S, Øvervatn A, Brech A, Johansen T (2009)
Monitoring autophagic degradation of p62/SQSTM1
Methods Enzymol, 452, 181-97
DOI 10.1016/S0076-6879(08)03612-4, PubMed 19200883

Pankiv S, Lamark T, Bruun JA, Øvervatn A, Bjørkøy G, Johansen T (2009)
Nucleocytoplasmic shuttling of p62/SQSTM1 and its role in recruitment of nuclear polyubiquitinated proteins to promyelocytic leukemia bodies
J Biol Chem, 285 (8), 5941-53
DOI 10.1074/jbc.M109.039925, PubMed 20018885

Publications 2007

Pandur S, Pankiv S, Johannessen M, Moens U, Huseby NE (2007)
Gamma-glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells
Free Radic Res, 41 (12), 1376-84
DOI 10.1080/10715760701739488, PubMed 18075840

Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T (2007)
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
J Biol Chem, 282 (33), 24131-45
DOI 10.1074/jbc.M702824200, PubMed 17580304

Publications 2005

Pankiv S, Møller S, Bjørkøy G, Moens U, Huseby NE (2005)
Radiation-induced upregulation of gamma-glutamyltransferase in colon carcinoma cells is mediated through the Ras signal transduction pathway
Biochim Biophys Acta, 1760 (2), 151-7
DOI 10.1016/j.bbagen.2005.11.006, PubMed 16386375

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