Publications from OUS - Skin- and head and neck cancer
99 publications found
Publications 2024
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Deep learning with uncertainty estimation for automatic tumor segmentation in PET/CT of head and neck cancers: impact of model complexity, image processing and augmentation
Biomed Phys Eng Express, 10 (5)
DOI 10.1088/2057-1976/ad6dcd, PubMed 39127060 -
Corrigendum: Head and neck cancer treatment outcome prediction: a comparison between machine learning with conventional radiomics features and deep learning radiomics
Front Med (Lausanne), 11, 1421603
DOI 10.3389/fmed.2024.1421603, PubMed 38813378 -
Chronic fatigue in long-term survivors of head and neck cancer treated with radiotherapy
Radiother Oncol, 195, 110231
DOI 10.1016/j.radonc.2024.110231, PubMed 38518958 -
Current aspects of the quality of head and neck cancer care - survey of the Scandinavian Society for Head and Neck Oncology
Acta Otolaryngol, 1-5 (in press)
DOI 10.1080/00016489.2024.2386097, PubMed 39109489 -
High-dose loco-regional pattern of failure after primary radiotherapy in p16 positive and negative head and neck squamous cell carcinoma - A DAHANCA 19 study
Clin Transl Radiat Oncol, 46, 100772
DOI 10.1016/j.ctro.2024.100772, PubMed 38596816 -
Tumor volume and cancer stem cell expression as prognostic markers for high-dose loco-regional failure in head and neck squamous cell carcinoma - A DAHANCA 19 study
Radiother Oncol, 193, 110149
DOI 10.1016/j.radonc.2024.110149, PubMed 38341096 -
Thoracic radiation in combination with erlotinib-results from a phase 2 randomized trial
Front Oncol, 14, 1412716
DOI 10.3389/fonc.2024.1412716, PubMed 39148905 -
Long-term health-related quality of life in head and neck cancer survivors: A large multinational study
Int J Cancer, 154 (10), 1772-1785
DOI 10.1002/ijc.34861, PubMed 38312044
Publications 2023
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Impact of hyperfractionated re-irradiation on quality of life in patients with recurrent or second primary head and neck cancer, a prospective single institutional study
Clin Transl Radiat Oncol, 42, 100654
DOI 10.1016/j.ctro.2023.100654, PubMed 37415638 -
Health-Related Quality of Life with Pembrolizumab in Patients with Locally Advanced or Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma: KEYNOTE-629
Dermatol Ther (Heidelb), 13 (12), 3165-3180
DOI 10.1007/s13555-023-01059-y, PubMed 37943491 -
An HPV-Vaccinated Patient With Human Papillomavirus-Positive Oropharyngeal Squamous Cell Carcinoma
JAMA Otolaryngol Head Neck Surg, 149 (1), 92-94
DOI 10.1001/jamaoto.2022.3762, PubMed 36416857 -
Automatic gross tumor segmentation of canine head and neck cancer using deep learning and cross-species transfer learning
Front Vet Sci, 10, 1143986
DOI 10.3389/fvets.2023.1143986, PubMed 37026102 -
Efficacy and Safety of Nivolumab Plus Ipilimumab vs Nivolumab Alone for Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: The Phase 2 CheckMate 714 Randomized Clinical Trial
JAMA Oncol, 9 (6), 779-789
DOI 10.1001/jamaoncol.2023.0147, PubMed 37022706 -
Head and neck cancer treatment outcome prediction: a comparison between machine learning with conventional radiomics features and deep learning radiomics
Front Med (Lausanne), 10, 1217037
DOI 10.3389/fmed.2023.1217037, PubMed 37711738 -
Radiation-induced long-term dysphagia in survivors of head and neck cancer and association with dose-volume parameters
Radiother Oncol, 190, 110044
DOI 10.1016/j.radonc.2023.110044, PubMed 38061420 -
Single-arm studies involving patient-reported outcome data in oncology: a literature review on current practice
Lancet Oncol, 24 (5), e197-e206
DOI 10.1016/S1470-2045(23)00110-9, PubMed 37142381 -
Setting International Standards in Analyzing Patient-Reported Outcomes and Quality of Life Endpoints in Cancer Clinical Trials-Innovative Medicines Initiative (SISAQOL-IMI): stakeholder views, objectives, and procedures
Lancet Oncol, 24 (6), e270-e283
DOI 10.1016/S1470-2045(23)00157-2, PubMed 37269858 -
N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells
J Biol Chem, 300 (1), 105509
DOI 10.1016/j.jbc.2023.105509, PubMed 38042493 -
Diagnosis of locally recurrent head and neck squamous cell carcinoma in the Nordic HNC centers and feasibility of the Odense-Birmingham definition
Acta Oncol, 62 (9), 1102-1105
DOI 10.1080/0284186X.2023.2245550, PubMed 37602835 -
Serious Long-Term Effects of Head and Neck Cancer from the Survivors' Point of View
Healthcare (Basel), 11 (6)
DOI 10.3390/healthcare11060906, PubMed 36981562 -
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
Crit Care, 27 (1), 9
DOI 10.1186/s13054-022-04205-8, PubMed 36627655
Publications 2022
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A multicenter international prospective study of the validity and reliability of a COVID-19-specific health-related quality of life questionnaire
Qual Life Res, 32 (2), 447-459
DOI 10.1007/s11136-022-03272-2, PubMed 36273365 -
Health-related quality of life in patients with COVID-19; international development of a patient-reported outcome measure
J Patient Rep Outcomes, 6 (1), 26
DOI 10.1186/s41687-022-00434-1, PubMed 35348945 -
Pembrolizumab Alone or With Chemotherapy for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma in KEYNOTE-048: Subgroup Analysis by Programmed Death Ligand-1 Combined Positive Score
J Clin Oncol, 40 (21), 2321-2332
DOI 10.1200/JCO.21.02198, PubMed 35333599 -
Mucosa-sparing dose painting of head and neck cancer
Acta Oncol, 61 (2), 141-145
DOI 10.1080/0284186X.2021.2022200, PubMed 34991431 -
Pembrolizumab With or Without Chemotherapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: Updated Results of the Phase III KEYNOTE-048 Study
J Clin Oncol, 41 (4), 790-802
DOI 10.1200/JCO.21.02508, PubMed 36219809 -
Associations between patient-reported late effects and systemic cytokines in long-term survivors of head and neck cancer treated with radiotherapy
J Cancer Surviv, 17 (4), 1082-1093
DOI 10.1007/s11764-022-01273-1, PubMed 36350483 -
Proteomic Profiling of Saliva and Tears in Radiated Head and Neck Cancer Patients as Compared to Primary Sjögren's Syndrome Patients
Int J Mol Sci, 23 (7)
DOI 10.3390/ijms23073714, PubMed 35409074 -
Body image concerns in long-term head and neck cancer survivors: prevalence and role of clinical factors and patient-reported late effects
J Cancer Surviv, 17 (2), 526-534
DOI 10.1007/s11764-022-01311-y, PubMed 36509859 -
Merkel cell carcinoma
Tidsskr Nor Laegeforen, 142 (9)
DOI 10.4045/tidsskr.21.0693, PubMed 35699540 -
cAMP-Mediated Autophagy Promotes Cell Survival via ROS-Induced Activation of PARP1: Implications for Treatment of Acute Lymphoblastic Leukemia
Mol Cancer Res, 20 (3), 400-411
DOI 10.1158/1541-7786.MCR-21-0652, PubMed 34880123 -
Pembrolizumab alone or with chemotherapy for recurrent or metastatic head and neck squamous cell carcinoma: Health-related quality-of-life results from KEYNOTE-048
Oral Oncol, 128, 105815
DOI 10.1016/j.oraloncology.2022.105815, PubMed 35381576
Publications 2021
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Health-related quality of life issues, including symptoms, in patients with active COVID-19 or post COVID-19; a systematic literature review
Qual Life Res, 30 (12), 3367-3381
DOI 10.1007/s11136-021-02908-z, PubMed 34146226 -
Alterations in meibomian glands in patients treated with intensity-modulated radiotherapy for head and neck cancer
Sci Rep, 11 (1), 22419
DOI 10.1038/s41598-021-01844-9, PubMed 34789830 -
A comparison of methods for fully automatic segmentation of tumors and involved nodes in PET/CT of head and neck cancers
Phys Med Biol, 66 (6), 065012
DOI 10.1088/1361-6560/abe553, PubMed 33666176 -
Deep learning-based auto-delineation of gross tumour volumes and involved nodes in PET/CT images of head and neck cancer patients
Eur J Nucl Med Mol Imaging, 48 (9), 2782-2792
DOI 10.1007/s00259-020-05125-x, PubMed 33559711 -
Methodological approach for determining the Minimal Important Difference and Minimal Important Change scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module (EORTC QLQ-HN43) exemplified by the Swallowing scale
Qual Life Res, 31 (3), 841-853
DOI 10.1007/s11136-021-02939-6, PubMed 34272632 -
Oral and ocular late effects in head and neck cancer patients treated with radiotherapy
Sci Rep, 11 (1), 4026
DOI 10.1038/s41598-021-83635-w, PubMed 33597629 -
Repeatability of hypoxia dose painting by numbers based on EF5-PET in head and neck cancer
Acta Oncol, 60 (11), 1386-1391
DOI 10.1080/0284186X.2021.1944663, PubMed 34184605
Publications 2020
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Radiotherapy-related lymphopenia in patients with advanced non-small cell lung cancer receiving palliative radiotherapy
Clin Transl Radiat Oncol, 22, 15-21
DOI 10.1016/j.ctro.2020.02.005, PubMed 32181373 -
Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways
Cells, 9 (9)
DOI 10.3390/cells9092050, PubMed 32911805 -
A Nordic-Baltic perspective on indications for proton therapy with strategies for identification of proper patients
Acta Oncol, 59 (10), 1157-1163
DOI 10.1080/0284186X.2020.1817977, PubMed 32902341 -
Long-term outcome in patients operated with hybrid esophagectomy for esophageal cancer - a cohort study
Acta Oncol, 59 (7), 859-865
DOI 10.1080/0284186X.2020.1750694, PubMed 32324079 -
The Role of Adjuvant Treatment in Craniofacial Malignancy: A Critical Review
Front Oncol, 10, 1402
DOI 10.3389/fonc.2020.01402, PubMed 32850452 -
Ongoing and future clinical trials in particle therapy in the Nordic countries
Acta Oncol, 59 (10), 1145-1150
DOI 10.1080/0284186X.2020.1792548, PubMed 32673134
Publications 2019
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Mapping Bone Marrow Response in the Vertebral Column by Positron Emission Tomography Following Radiotherapy and Erlotinib Therapy of Lung Cancer
Mol Imaging Biol, 21 (2), 391-398
DOI 10.1007/s11307-018-1226-7, PubMed 29916117 -
Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study
Lancet, 394 (10212), 1915-1928
DOI 10.1016/S0140-6736(19)32591-7, PubMed 31679945 -
Treatment of Sinonasal Adenocarcinoma: A Population-Based Prospective Cohort Study
J Neurol Surg B Skull Base, 81 (6), 627-637
DOI 10.1055/s-0039-1694050, PubMed 33381366 -
Squamous Cell Carcinoma of the Paranasal Sinuses: A Single Center Experience
J Neurol Surg B Skull Base, 81 (6), 664-672
DOI 10.1055/s-0039-1694967, PubMed 33381371 -
The prognostic role of 18F-fluorodeoxyglucose PET in head and neck cancer depends on HPV status
Radiother Oncol, 140, 54-61
DOI 10.1016/j.radonc.2019.05.019, PubMed 31177043 -
Targeting cyclooxygenase by indomethacin decelerates progression of acute lymphoblastic leukemia in a xenograft model
Blood Adv, 3 (21), 3181-3190
DOI 10.1182/bloodadvances.2019000473, PubMed 31698450 -
International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43: Phase IV
Head Neck, 41 (6), 1725-1737
DOI 10.1002/hed.25609, PubMed 30636188
Publications 2018
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Proton therapy - a reality in Norway from 2023
Tidsskr Nor Laegeforen, 138 (13)
DOI 10.4045/tidsskr.18.0250, PubMed 30180494 -
Serum cytokine profiles and metabolic tumor burden in patients with non-small cell lung cancer undergoing palliative thoracic radiation therapy
Adv Radiat Oncol, 3 (2), 130-138
DOI 10.1016/j.adro.2017.12.007, PubMed 29904737 -
Patients know their own health best
Tidsskr. Nor. Laegeforen., 138 (8), 716-718 -
cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53
Oncotarget, 9 (54), 30434-30449
DOI 10.18632/oncotarget.25758, PubMed 30100998 -
Dose painting for re-irradiation of head and neck cancer
Acta Oncol, 57 (12), 1693-1699
DOI 10.1080/0284186X.2018.1512753, PubMed 30280623
Publications 2017
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Assessment of pulmonary 18F-FDG-PET uptake and cytokine profiles in non-small cell lung cancer patients treated with radiotherapy and erlotinib
Clin Transl Radiat Oncol, 4, 57-63
DOI 10.1016/j.ctro.2017.04.002, PubMed 29594209 -
A new method to assess pulmonary changes using 18F-fluoro-2-deoxyglucose positron emission tomography for lung cancer patients following radiotherapy
Acta Oncol, 56 (11), 1597-1603
DOI 10.1080/0284186X.2017.1349336, PubMed 28849707 -
Improved treatment decisions in patients with esophageal cancer
Acta Oncol, 56 (10), 1286-1294
DOI 10.1080/0284186X.2017.1346379, PubMed 28686501 -
Patterns of local-regional recurrence after conformal and intensity-modulated radiotherapy for head and neck cancer
Radiat Oncol, 12 (1), 87
DOI 10.1186/s13014-017-0829-5, PubMed 28545588 -
Combining radioiodine and external beam radiation therapy: the potential of integrated treatment planning for differentiated thyroid cancer
Acta Oncol, 56 (6), 894-897
DOI 10.1080/0284186X.2017.1286384, PubMed 28464741 -
Head and neck cancer management in the Nordic countries: an effort to harmonize treatment
Eur Arch Otorhinolaryngol, 274 (5), 2363-2365
DOI 10.1007/s00405-017-4456-4, PubMed 28124110
Publications 2016
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Cervical lymph node metastases of squamous cell carcinoma of unknown origin: the diagnostic value of FDG PET/CT and clinical outcome
Eur Arch Otorhinolaryngol, 274 (2), 1015-1019
DOI 10.1007/s00405-016-4318-5, PubMed 27671150 -
The MYCN-HMGA2-CDKN2A pathway in non-small cell lung carcinoma--differences in histological subtypes
BMC Cancer, 16, 71
DOI 10.1186/s12885-016-2104-9, PubMed 26858029 -
Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2 × 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol
Eur Heart J, 37 (21), 1671-80
DOI 10.1093/eurheartj/ehw022, PubMed 26903532
Publications 2015
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Dose painting by numbers in a standard treatment planning system using inverted dose prescription maps
Acta Oncol, 54 (9), 1607-13
DOI 10.3109/0284186X.2015.1061690, PubMed 26213311
Publications 2014
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Influence of radical prostatectomy for prostate cancer on work status and working life 3 years after surgery
J Cancer Surviv, 9 (2), 172-9
DOI 10.1007/s11764-014-0399-6, PubMed 25216609 -
[Re: Brachytherapy for malignant uveal melanoma]
Tidsskr Nor Laegeforen, 134 (8), 814
DOI 10.4045/tidsskr.14.0467, PubMed 24780973 -
[Dental health when using bisphosphonates against breast cancer]
Tidsskr Nor Laegeforen, 134 (15), 1451
DOI 10.4045/tidsskr.14.0717, PubMed 25138400 -
Man with macrocephaly, learning disability and multiple basal cell carcinomas
Tidsskr Nor Laegeforen, 134 (11), 1151-4
DOI 10.4045/tidsskr.13.0894, PubMed 24939783
Publications 2013
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Palliative brachytherapy with or without primary stent placement in patients with oesophageal cancer, a randomised phase III trial
Radiother Oncol, 107 (3), 428-33
DOI 10.1016/j.radonc.2013.04.008, PubMed 23647761 -
Return to work and sick leave after radical prostatectomy: a prospective clinical study
Acta Oncol, 53 (6), 744-51
DOI 10.3109/0284186X.2013.844357, PubMed 24195691 -
[Cardioprotective treatment during adjuvant cancer therapy]
Tidsskr Nor Laegeforen, 133 (17), 1832-6
DOI 10.4045/tidsskr.12.1514, PubMed 24042297 -
Bisphosphonate-related osteonecrosis of the jaw in four Nordic countries and an indication of under-reporting
Acta Odontol Scand, 71 (6), 1386-90
DOI 10.3109/00016357.2013.764007, PubMed 23351164 -
Hypoxic tumor kinase signaling mediated by STAT5A in development of castration-resistant prostate cancer
PLoS One, 8 (5), e63723
DOI 10.1371/journal.pone.0063723, PubMed 23675504
Publications 2012
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Patient-reported outcomes evaluating palliative radiotherapy and chemotherapy in patients with oesophageal cancer: a systematic review
Acta Oncol, 52 (4), 679-90
DOI 10.3109/0284186X.2012.731521, PubMed 23190360 -
Rationale and design of the prevention of cardiac dysfunction during an Adjuvant Breast Cancer Therapy (PRADA) Trial
Cardiology, 123 (4), 240-7
DOI 10.1159/000343622, PubMed 23207160 -
The EORTC QLQ-OH17: a supplementary module to the EORTC QLQ-C30 for assessment of oral health and quality of life in cancer patients
Eur J Cancer, 48 (14), 2203-11
DOI 10.1016/j.ejca.2012.04.003, PubMed 22572480 -
Sixty cases of extreme osteonecrosis and osteomyelitis of the mandible and maxilla in a West African population
Int J Oral Maxillofac Surg, 41 (8), 978-85
DOI 10.1016/j.ijom.2012.04.022, PubMed 22652445 -
Oral health is an important issue in end-of-life cancer care
Support Care Cancer, 20 (12), 3115-22
DOI 10.1007/s00520-012-1441-8, PubMed 22434497
Publications 2011
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Palliative interventions and prognosis in patients with advanced esophageal cancer
Dis Esophagus, 24 (7), 502-9
DOI 10.1111/j.1442-2050.2010.01174.x, PubMed 21309923
Publications 2010
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CT density in lung cancer patients after radiotherapy sensitized by metoclopramide. A subgroup analysis of a randomized trial
Strahlenther Onkol, 186 (3), 163-8
DOI 10.1007/s00066-010-2040-6, PubMed 20165821 -
Prevention and treatment of trismus in head and neck cancer: A case report and a systematic review of the literature
Scand J Pain, 1 (2), 84-88
DOI 10.1016/j.sjpain.2010.01.006, PubMed 29913945
Publications 2008
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[Molecular targeted therapy in colorectal cancer]
Tidsskr Nor Laegeforen, 128 (2), 190-3
PubMed 18202731
Publications 2006
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DNA damage responses in cell cycle G2 phase and mitosis--tracking and targeting
Anticancer Res, 26 (3A), 1909-16
PubMed 16827124 -
[Oral manifestations in HIV infection]
Tidsskr Nor Laegeforen, 126 (9), 1218-21
PubMed 16670745
Publications 2005
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Norwegian LongoVital and recurrent aphthous ulceration: a randomized, double-blind, placebo-controlled study
Oral Dis, 11 (6), 374-8
DOI 10.1111/j.1601-0825.2005.01133.x, PubMed 16269029 -
Cell cycle checkpoint signaling involved in histone deacetylase inhibition and radiation-induced cell death
Mol Cancer Ther, 4 (8), 1231-8
DOI 10.1158/1535-7163.MCT-04-0304, PubMed 16093439
Publications 2004
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Potentiation of cell killing by fractionated radiation and suppression of proliferative recovery in MCF-7 breast tumor cells by the Vitamin D3 analog EB 1089
J Steroid Biochem Mol Biol, 92 (5), 365-74
DOI 10.1016/j.jsbmb.2004.07.011, PubMed 15698541 -
Inhibitory targeting of checkpoint kinase signaling overrides radiation-induced cell cycle gene regulation: a therapeutic strategy in tumor cell radiosensitization?
Radiother Oncol, 72 (3), 305-10
DOI 10.1016/j.radonc.2004.07.002, PubMed 15450729 -
Ionizing radiation inhibits the PLK cell cycle gene in a G2 checkpoint-dependent manner
Anticancer Res, 24 (2B), 555-62
PubMed 15160994
Publications 2003
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Changes in treatment volume of hormonally treated and untreated cancerous prostate and its impact on rectal dose
Acta Oncol, 42 (1), 10-4
DOI 10.1080/0891060310002177, PubMed 12665325 -
Repression of mRNA for the PLK cell cycle gene after DNA damage requires BRCA1
Oncogene, 22 (55), 8952-5
DOI 10.1038/sj.onc.1207000, PubMed 14654792
Publications 2002
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[Updated when it comes to the prevention of restenosis?]
Tidsskr Nor Laegeforen, 122 (17), 1720; author reply 1720
PubMed 12555618 -
Modeling volume effects of experimental brachytherapy in the rat rectum: uncovering the limitations of a radiobiologic concept
Int J Radiat Oncol Biol Phys, 53 (4), 1014-22
DOI 10.1016/s0360-3016(02)02835-3, PubMed 12095571 -
Clinical and cell line specific expression profiles of a human gene identified in experimental central nervous system metastases
Anticancer Res, 22 (4), 1949-57
PubMed 12174869
Publications 1996
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Mouthrinses containing triclosan reduce the incidence of recurrent aphthous ulcers (RAU)
J Clin Periodontol, 23 (8), 778-81
DOI 10.1111/j.1600-051x.1996.tb00609.x, PubMed 8877665
Publications 1994
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Inhibitory effects of HgCl2 on excitation-secretion coupling at the motor nerve terminal and excitation-contraction coupling in the muscle cell
Cell Mol Neurobiol, 14 (6), 623-36
DOI 10.1007/BF02088672, PubMed 7543823