Publications 2023

Richartz N, Pietka W, Yadav A, Bostad M, Bhagwat S, Naderi S, Naderi EH, Stokke T, Ruud E, Blomhoff HK (2023)
N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells
J Biol Chem, 300 (1), 105509
DOI 10.1016/j.jbc.2023.105509, PubMed 38042493

Publications 2022

Richartz N, Pietka W, Gilljam KM, Skah S, Skålhegg BS, Bhagwat S, Naderi EH, Ruud E, Blomhoff HK (2022)
cAMP-Mediated Autophagy Promotes Cell Survival via ROS-Induced Activation of PARP1: Implications for Treatment of Acute Lymphoblastic Leukemia
Mol Cancer Res, 20 (3), 400-411
DOI 10.1158/1541-7786.MCR-21-0652, PubMed 34880123

Publications 2019

Richartz N, Duthil E, Ford A, Naderi EH, Bhagwat S, Gilljam KM, Burman MM, Ruud E, Blomhoff HK, Skah S (2019)
Targeting cyclooxygenase by indomethacin decelerates progression of acute lymphoblastic leukemia in a xenograft model
Blood Adv, 3 (21), 3181-3190
DOI 10.1182/bloodadvances.2019000473, PubMed 31698450

Publications 2018

Skah S, Richartz N, Duthil E, Gilljam KM, Bindesbøll C, Naderi EH, Eriksen AB, Ruud E, Dirdal MM, Simonsen A, Blomhoff HK (2018)
cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53
Oncotarget, 9 (54), 30434-30449
DOI 10.18632/oncotarget.25758, PubMed 30100998

Publications 2017

Arguinano AA, Naderi E, Ndiaye NC, Stathopoulou M, Dadé S, Alizadeh B, Visvikis-Siest S (2017)
IL6R haplotype rs4845625*T/rs4537545*C is a risk factor for simultaneously high CRP, LDL and ApoB levels
Genes Immun, 18 (3), 163-169
DOI 10.1038/gene.2017.16, PubMed 28769070

Publications 2016

Holm KL, Indrevaer RL, Myklebust JH, Kolstad A, Moskaug JØ, Naderi EH, Blomhoff HK (2016)
Myeloid cell leukaemia 1 has a vital role in retinoic acid-mediated protection of Toll-like receptor 9-stimulated B cells from spontaneous and DNA damage-induced apoptosis
Immunology, 149 (1), 62-73
DOI 10.1111/imm.12629, PubMed 27278254

Publications 2015

Follin-Arbelet V, Misund K, Naderi EH, Ugland H, Sundan A, Blomhoff HK (2015)
The natural compound forskolin synergizes with dexamethasone to induce cell death in myeloma cells via BIM
Sci Rep, 5, 13001
DOI 10.1038/srep13001, PubMed 26306624

Naderi EH, Skah S, Ugland H, Myklebost O, Sandnes DL, Torgersen ML, Josefsen D, Ruud E, Naderi S, Blomhoff HK (2015)
Bone marrow stroma-derived PGE2 protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death
Mol Cancer, 14 (1), 14
DOI 10.1186/s12943-014-0278-9, PubMed 25623255

Publications 2013

Follin-Arbelet V, Torgersen ML, Naderi EH, Misund K, Sundan A, Blomhoff HK (2013)
Death of multiple myeloma cells induced by cAMP-signaling involves downregulation of Mcl-1 via the JAK/STAT pathway
Cancer Lett, 335 (2), 323-31
DOI 10.1016/j.canlet.2013.02.042, PubMed 23454584

Indrevær RL, Holm KL, Aukrust P, Osnes LT, Naderi EH, Fevang B, Blomhoff HK (2013)
Retinoic acid improves defective TLR9/RP105-induced immune responses in common variable immunodeficiency-derived B cells
J Immunol, 191 (7), 3624-33
DOI 10.4049/jimmunol.1300213, PubMed 24006462

Kloster MM, Naderi EH, Haaland I, Gjertsen BT, Blomhoff HK, Naderi S (2013)
cAMP signalling inhibits p53 acetylation and apoptosis via HDAC and SIRT deacetylases
Int J Oncol, 42 (5), 1815-21
DOI 10.3892/ijo.2013.1853, PubMed 23483263

Naderi EH, Ugland HK, Diep PP, Josefsen D, Ruud E, Naderi S, Blomhoff HK (2013)
Selective inhibition of cell death in malignant vs normal B-cell precursors: implications for cAMP in development and treatment of BCP-ALL
Blood, 121 (10), 1805-13
DOI 10.1182/blood-2012-08-452698, PubMed 23299313

Publications 2011

Kloster MM, Naderi EH, Carlsen H, Blomhoff HK, Naderi S (2011)
Hyperactivation of NF-κB via the MEK signaling is indispensable for the inhibitory effect of cAMP on DNA damage-induced cell death
Mol Cancer, 10, 45
DOI 10.1186/1476-4598-10-45, PubMed 21510868

Naderi EH, Jochemsen AG, Blomhoff HK, Naderi S (2011)
Activation of cAMP signaling interferes with stress-induced p53 accumulation in ALL-derived cells by promoting the interaction between p53 and HDM2
Neoplasia, 13 (7), 653-63
DOI 10.1593/neo.11542, PubMed 21750659

Publications 2009

Naderi EH, Findley HW, Ruud E, Blomhoff HK, Naderi S (2009)
Activation of cAMP signaling inhibits DNA damage-induced apoptosis in BCP-ALL cells through abrogation of p53 accumulation
Blood, 114 (3), 608-18
DOI 10.1182/blood-2009-02-204883, PubMed 19451550

Publications 2008

Kloster MM, Hafte TT, Moltzau LR, Naderi EH, Dahle MK, Skålhegg BS, Gaudernack G, Levy FO, Naderi S, Blomhoff HK (2008)
EBV infection renders B cells resistant to growth inhibition via adenylyl cyclase
Cell Signal, 20 (6), 1169-78
DOI 10.1016/j.cellsig.2008.02.007, PubMed 18406106