Publications by Pål Kristian Selbo

68 publications found

Publications 2024

  1. Selbo PK, Korbelik M (2024)
    Topical collection on photodynamic therapy-enhanced antitumour immunity
    Photochem Photobiol Sci, 23 (2), 213-214
    DOI 10.1007/s43630-024-00549-y, PubMed 38381362

Publications 2022

  1. Trojan J, Hoffmeister A, Neu B, Kasper S, Dechêne A, Jürgensen C, Schirra J, Jakobs R, Palmer D, Selbo PK, Olivecrona H, Finnesand L, Høgset A, Walday P, Sturgess R (2022)
    Photochemical Internalization of Gemcitabine Is Safe and Effective in Locally Advanced Inoperable Cholangiocarcinoma
    Oncologist, 27 (6), 430-e433
    DOI 10.1093/oncolo/oyab074, PubMed 35675633
  2. Wong JJW, Lorenz S, Selbo PK (2022)
    All-trans retinoic acid enhances the anti-tumour effects of fimaporfin-based photodynamic therapy
    Biomed Pharmacother, 155, 113678
    DOI 10.1016/j.biopha.2022.113678, PubMed 36108391

Publications 2021

  1. Otterhaug T, Janetzki S, Welters MJP, Håkerud M, Nedberg AG, Edwards VT, Boekestijn S, Loof NM, Selbo PK, Olivecrona H, van der Burg SH, Høgset A (2021)
    Photochemical Internalization Enhanced Vaccination Is Safe, and Gives Promising Cellular Immune Responses to an HPV Peptide-Based Vaccine in a Phase I Clinical Study in Healthy Volunteers
    Front Immunol, 11, 576756
    DOI 10.3389/fimmu.2020.576756, PubMed 33488576
  2. Vikan AK, Kostas M, Haugsten EM, Selbo PK, Wesche J (2021)
    Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1
    Cells, 10 (6)
    DOI 10.3390/cells10061476, PubMed 34204611
  3. Weisheit S, Wegner CS, Ailte I, Radulovic M, Weyergang A, Selbo PK, Brech A (2021)
    Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
    Biochem Pharmacol, 194, 114837
    DOI 10.1016/j.bcp.2021.114837, PubMed 34780750
  4. Wong JJW, Selbo PK (2021)
    Light-controlled elimination of PD-L1+ cells
    J Photochem Photobiol B, 225, 112355
    DOI 10.1016/j.jphotobiol.2021.112355, PubMed 34768077

Publications 2020

  1. Jerjes W, Theodossiou TA, Hirschberg H, Høgset A, Weyergang A, Selbo PK, Hamdoon Z, Hopper C, Berg K (2020)
    Photochemical Internalization for Intracellular Drug Delivery. From Basic Mechanisms to Clinical Research
    J Clin Med, 9 (2)
    DOI 10.3390/jcm9020528, PubMed 32075165
  2. Šošić L, Selbo PK, Kotkowska ZK, Kündig TM, Høgset A, Johansen P (2020)
    Photochemical Internalization: Light Paves Way for New Cancer Chemotherapies and Vaccines
    Cancers (Basel), 12 (1)
    DOI 10.3390/cancers12010165, PubMed 31936595
  3. Wong JJW, Berstad MB, Fremstedal ASV, Berg K, Patzke S, Sørensen V, Peng Q, Selbo PK, Weyergang A (2020)
    Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy
    Cancers (Basel), 12 (2)
    DOI 10.3390/cancers12020417, PubMed 32053965
  4. Wong JJW, Selbo PK (2020)
    High aldehyde dehydrogenase activity does not protect colon cancer cells against TPCS2a-sensitized photokilling
    Photochem Photobiol Sci, 19 (3), 308-312
    DOI 10.1039/c9pp00453j, PubMed 32108197

Publications 2019

  1. Ney A, Mahamed I, Garcia-Sampedro A, Selbo PK, Sancho P, MacRobert AJ, Pereira SP, Acedo P (2019)
    Combination light-based therapies to treat pancreatic cancer: a proof of concept
    PROC SPIE, 11070, UNSP 1107045
    DOI 10.1117/12.2525305
  2. Olsen CE, Cheung LH, Weyergang A, Berg K, Vallera DA, Rosenblum MG, Selbo PK (2019)
    Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization
    J Clin Med, 9 (1)
    DOI 10.3390/jcm9010068, PubMed 31888091

Publications 2018

  1. Eng MS, Kaur J, Prasmickaite L, Engesæter BØ, Weyergang A, Skarpen E, Berg K, Rosenblum MG, Mælandsmo GM, Høgset A, Ferrone S, Selbo PK (2018)
    Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins
    Photochem Photobiol Sci, 17 (5), 539-551
    DOI 10.1039/C7PP00358G, PubMed 29565434
  2. Haug M, Brede G, Håkerud M, Nedberg AG, Gederaas OA, Flo TH, Edwards VT, Selbo PK, Høgset A, Halaas Ø (2018)
    Photochemical Internalization of Peptide Antigens Provides a Novel Strategy to Realize Therapeutic Cancer Vaccination
    Front Immunol, 9, 650
    DOI 10.3389/fimmu.2018.00650, PubMed 29670624
  3. Zhang X, de Boer L, Heiliegers L, Man-Bovenkerk S, Selbo PK, Drijfhout JW, Høgset A, Zaat SAJ (2018)
    Photochemical internalization enhances cytosolic release of antibiotic and increases its efficacy against staphylococcal infection
    J Control Release, 283, 214-222
    DOI 10.1016/j.jconrel.2018.06.004, PubMed 29883696

Publications 2017

  1. Lund K, Olsen CE, Wong JJW, Olsen PA, Solberg NT, Høgset A, Krauss S, Selbo PK (2017)
    5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin
    J Exp Clin Cancer Res, 36 (1), 187
    DOI 10.1186/s13046-017-0662-6, PubMed 29258566
  2. Olsen CE, Weyergang A, Edwards VT, Berg K, Brech A, Weisheit S, Høgset A, Selbo PK (2017)
    Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
    Biochem Pharmacol, 144, 63-77
    DOI 10.1016/j.bcp.2017.08.002, PubMed 28784290

Publications 2015

  1. Bostad M, Olsen CE, Peng Q, Berg K, Høgset A, Selbo PK (2015)
    Light-controlled endosomal escape of the novel CD133-targeting immunotoxin AC133-saporin by photochemical internalization - A minimally invasive cancer stem cell-targeting strategy
    J Control Release, 206, 37-48
    DOI 10.1016/j.jconrel.2015.03.008, PubMed 25758331
  2. Selbo PK, Bostad M, Olsen CE, Edwards VT, Høgset A, Weyergang A, Berg K (2015)
    Photochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics
    Photochem Photobiol Sci, 14 (8), 1433-50
    DOI 10.1039/c5pp00027k, PubMed 25805311
  3. Weyergang A, Berstad ME, Bull-Hansen B, Olsen CE, Selbo PK, Berg K (2015)
    Photochemical activation of drugs for the treatment of therapy-resistant cancers
    Photochem Photobiol Sci, 14 (8), 1465-75
    DOI 10.1039/c5pp00029g, PubMed 25849953

Publications 2014

  1. Bostad M, Kausberg M, Weyergang A, Olsen CE, Berg K, Høgset A, Selbo PK (2014)
    Light-triggered, efficient cytosolic release of IM7-saporin targeting the putative cancer stem cell marker CD44 by photochemical internalization
    Mol Pharm, 11 (8), 2764-76
    DOI 10.1021/mp500129t, PubMed 24960585
  2. Håkerud M, Selbo PK, Waeckerle-Men Y, Contassot E, Dziunycz P, Kündig TM, Høgset A, Johansen P (2014)
    Photosensitisation facilitates cross-priming of adjuvant-free protein vaccines and stimulation of tumour-suppressing CD8 T cells
    J Control Release, 198, 10-7
    DOI 10.1016/j.jconrel.2014.11.032, PubMed 25482339
  3. Lund K, Bostad M, Skarpen E, Braunagel M, Kiprijanov S, Krauss S, Duncan A, Høgset A, Selbo PK (2014)
    The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
    MAbs, 6 (4), 1038-50
    DOI 10.4161/mabs.28207, PubMed 24525727
  4. Repetto-Llamazares AH, Larsen RH, Giusti AM, Riccardi E, Bruland ØS, Selbo PK, Dahle J (2014)
    177Lu-DOTA-HH1, a novel anti-CD37 radio-immunoconjugate: a study of toxicity in nude mice
    PLoS One, 9 (7), e103070
    DOI 10.1371/journal.pone.0103070, PubMed 25068508

Publications 2013

  1. Bostad M, Berg K, Høgset A, Skarpen E, Stenmark H, Selbo PK (2013)
    Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
    J Control Release, 168 (3), 317-26
    DOI 10.1016/j.jconrel.2013.03.023, PubMed 23567040
  2. Håkerud M, Waeckerle-Men Y, Selbo PK, Kündig TM, Høgset A, Johansen P (2013)
    Intradermal photosensitisation facilitates stimulation of MHC class-I restricted CD8 T-cell responses of co-administered antigen
    J Control Release, 174, 143-50
    DOI 10.1016/j.jconrel.2013.11.017, PubMed 24280261
  3. Olsen CE, Berg K, Selbo PK, Weyergang A (2013)
    Circumvention of resistance to photodynamic therapy in doxorubicin-resistant sarcoma by photochemical internalization of gelonin
    Free Radic Biol Med, 65, 1300-1309
    DOI 10.1016/j.freeradbiomed.2013.09.010, PubMed 24076428
  4. Stratford EW, Bostad M, Castro R, Skarpen E, Berg K, Høgset A, Myklebost O, Selbo PK (2013)
    Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity
    Biochim Biophys Acta, 1830 (8), 4235-43
    DOI 10.1016/j.bbagen.2013.04.033, PubMed 23643966
  5. Vikdal M, Weyergang A, Selbo PK, Berg K (2013)
    Vascular endothelial cells as targets for photochemical internalization (PCI)
    Photochem Photobiol, 89 (5), 1185-92
    DOI 10.1111/php.12126, PubMed 23819771
  6. Weyergang A, Selbo PK, Berg K (2013)
    Sustained ERK [corrected] inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy
    Biochim Biophys Acta, 1830 (3), 2659-70
    DOI 10.1016/j.bbagen.2012.11.010, PubMed 23671927
  7. Weyergang A, Selbo PK, Berg K (2013)
    Sustained ERK inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy (vol 1830, pg 2659, 2013)
    Biochim. Biophys. Acta-Gen. Subj., 1830 (10), 4417
    DOI 10.1016/j.bbagen.2013.05.002

Publications 2012

  1. Abu-Yousif AO, Moor AC, Zheng X, Savellano MD, Yu W, Selbo PK, Hasan T (2012)
    Epidermal growth factor receptor-targeted photosensitizer selectively inhibits EGFR signaling and induces targeted phototoxicity in ovarian cancer cells
    Cancer Lett, 321 (2), 120-7
    DOI 10.1016/j.canlet.2012.01.014, PubMed 22266098
  2. Selbo PK, Weyergang A, Eng MS, Bostad M, Mælandsmo GM, Høgset A, Berg K (2012)
    Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug
    J Control Release, 159 (2), 197-203
    DOI 10.1016/j.jconrel.2012.02.003, PubMed 22349185

Publications 2011

  1. Berg K, Nordstrand S, Selbo PK, Tran DT, Angell-Petersen E, Høgset A (2011)
    Disulfonated tetraphenyl chlorin (TPCS2a), a novel photosensitizer developed for clinical utilization of photochemical internalization
    Photochem Photobiol Sci, 10 (10), 1637-51
    DOI 10.1039/c1pp05128h, PubMed 21773635
  2. Weyergang A, Selbo PK, Berstad ME, Bostad M, Berg K (2011)
    Photochemical internalization of tumor-targeted protein toxins
    Lasers Surg Med, 43 (7), 721-33
    DOI 10.1002/lsm.21084, PubMed 22057500

Publications 2010

  1. Berg K, Berstad M, Prasmickaite L, Weyergang A, Selbo PK, Hedfors I, Høgset A (2010)
    Photochemical internalization: a new tool for gene and oligonucleotide delivery
    Top Curr Chem, 296, 251-81
    DOI 10.1007/128_2010_63, PubMed 21504105
  2. Berg K, Weyergang A, Prasmickaite L, Bonsted A, Høgset A, Strand MT, Wagner E, Selbo PK (2010)
    Photochemical internalization (PCI): a technology for drug delivery
    Methods Mol Biol, 635, 133-45
    DOI 10.1007/978-1-60761-697-9_10, PubMed 20552345
  3. Johansen P, Berg K, Selbo PK, Hofbauer GF (2010)
    [Photochemical internalisation (PCI): a further development of photodynamic therapy for the treatment of skin cancer]
    Praxis (Bern 1994), 99 (23), 1423-8
    DOI 10.1024/1661-8157/a000310, PubMed 21082595
  4. Selbo PK, Weyergang A, Høgset A, Norum OJ, Berstad MB, Vikdal M, Berg K (2010)
    Photochemical internalization provides time- and space-controlled endolysosomal escape of therapeutic molecules
    J Control Release, 148 (1), 2-12
    DOI 10.1016/j.jconrel.2010.06.008, PubMed 20600406

Publications 2009

  1. Norum OJ, Selbo PK, Weyergang A, Giercksky KE, Berg K (2009)
    Photochemical internalization (PCI) in cancer therapy: from bench towards bedside medicine
    J Photochem Photobiol B, 96 (2), 83-92
    DOI 10.1016/j.jphotobiol.2009.04.012, PubMed 19467605
  2. Selbo PK, Rosenblum MG, Cheung LH, Zhang W, Berg K (2009)
    Multi-modality therapeutics with potent anti-tumor effects: photochemical internalization enhances delivery of the fusion toxin scFvMEL/rGel
    PLoS One, 4 (8), e6691
    DOI 10.1371/journal.pone.0006691, PubMed 19690617
  3. Weyergang A, Berg K, Kaalhus O, Peng Q, Selbo PK (2009)
    Photodynamic therapy targets the mTOR signaling network in vitro and in vivo
    Mol Pharm, 6 (1), 255-64
    DOI 10.1021/mp800156e, PubMed 19125612
  4. Woodhams J, Lou PJ, Selbo PK, Mosse A, Oukrif D, MacRobert A, Novelli M, Peng Q, Berg K, Bown SG (2009)
    Intracellular re-localisation by photochemical internalisation enhances the cytotoxic effect of gelonin--quantitative studies in normal rat liver
    J Control Release, 142 (3), 347-53
    DOI 10.1016/j.jconrel.2009.11.017, PubMed 19932724

Publications 2007

  1. Berg K, Folini M, Prasmickaite L, Selbo PK, Bonsted A, Engesaeter BØ, Zaffaroni N, Weyergang A, Dietze A, Maelandsmo GM, Wagner E, Norum OJ, Høgset A (2007)
    Photochemical internalization: a new tool for drug delivery
    Curr Pharm Biotechnol, 8 (6), 362-72
    DOI 10.2174/138920107783018354, PubMed 18289045
  2. Melhus KB, Larsen RH, Stokke T, Kaalhus O, Selbo PK, Dahle J (2007)
    Evaluation of the binding of radiolabeled rituximab to CD20-positive lymphoma cells: an in vitro feasibility study concerning low-dose-rate radioimmunotherapy with the alpha-emitter 227Th
    Cancer Biother Radiopharm, 22 (4), 469-79
    DOI 10.1089/cbr.2007.371, PubMed 17803441
  3. Weyergang A, Selbo PK, Berg K (2007)
    Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor
    Biochem Pharmacol, 74 (2), 226-35
    DOI 10.1016/j.bcp.2007.04.018, PubMed 17531956
  4. Yip WL, Weyergang A, Berg K, Tønnesen HH, Selbo PK (2007)
    Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells
    Mol Pharm, 4 (2), 241-51
    DOI 10.1021/mp060105u, PubMed 17263556

Publications 2006

  1. Berg K, Høgset A, Prasmickaite L, Weyergang A, Bonsted A, Dietze A, Lou PJ, Bown S, Norum OJ, Møllergard HM, Selbo PK (2006)
    Photochemical internalization (PCI): A novel technology for activation of endocytosed therapeutic agents.
    Med Laser Appl, 21, 239-251
    DOI 10.1016/j.mla.2006.08.004, PublikaID 73
  2. Dietze A, Selbo PK, Prasmickaite L, Weyergang A, Bonsted A, Engesaeter B, Hogset A, Berg K (2006)
    Photochemical internalization (PCI): a new modality for light activation of endocytosed therapeuticals
    J Environ Pathol Toxicol Oncol, 25 (1-2), 521-36
    DOI 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.330, PubMed 16566739
  3. Selbo PK, Weyergang A, Bonsted A, Bown SG, Berg K (2006)
    Photochemical internalization of therapeutic macromolecular agents: a novel strategy to kill multidrug-resistant cancer cells
    J Pharmacol Exp Ther, 319 (2), 604-12
    DOI 10.1124/jpet.106.109165, PubMed 16902053
  4. Solban N, Selbo PK, Sinha AK, Chang SK, Hasan T (2006)
    Mechanistic investigation and implications of photodynamic therapy induction of vascular endothelial growth factor in prostate cancer
    Cancer Res, 66 (11), 5633-40
    DOI 10.1158/0008-5472.CAN-06-0604, PubMed 16740700
  5. Weyergang A, Selbo PK, Berg K (2006)
    Photochemically stimulated drug delivery increases the cytotoxicity and specificity of EGF-saporin
    J Control Release, 111 (1-2), 165-73
    DOI 10.1016/j.jconrel.2005.12.002, PubMed 16466823

Publications 2005

  1. Berg K, Selbo PK, Weyergang A, Dietze A, Prasmickaite L, Bonsted A, Engesaeter BØ, Angell-Petersen E, Warloe T, Frandsen N, Høgset A (2005)
    Porphyrin-related photosensitizers for cancer imaging and therapeutic applications
    J Microsc, 218 (Pt 2), 133-47
    DOI 10.1111/j.1365-2818.2005.01471.x, PubMed 15857375
  2. Dietze A, Peng Q, Selbo PK, Kaalhus O, Müller C, Bown S, Berg K (2005)
    Enhanced photodynamic destruction of a transplantable fibrosarcoma using photochemical internalisation of gelonin
    Br J Cancer, 92 (11), 2004-9
    DOI 10.1038/sj.bjc.6602600, PubMed 15886704

Publications 2004

  1. Berg K, Selbo PK, Prasmickaite L, Høgset A (2004)
    Photochemical drug and gene delivery
    Curr Opin Mol Ther, 6 (3), 279-87
    PubMed 15264430
  2. Høgset A, Prasmickaite L, Selbo PK, Hellum M, Engesaeter BØ, Bonsted A, Berg K (2004)
    Photochemical internalisation in drug and gene delivery
    Adv Drug Deliv Rev, 56 (1), 95-115
    DOI 10.1016/j.addr.2003.08.016, PubMed 14706447

Publications 2003

  1. Berg K, Prasmickaite L, Selbo PK, Hellum M, Bonsted A, Høgset A (2003)
    Photochemical internalization (PCI)--a novel technology for release of macromolecules from endocytic vesicles
    Oftalmologia, 56 (1), 67-71
    PubMed 12886687
  2. Høgset A, Prasmickaite L, Engesaeter BO, Hellum M, Selbo PK, Olsen VM, Maelandsmo GM, Berg K (2003)
    Light directed gene transfer by photochemical internalisation
    Curr Gene Ther, 3 (2), 89-112
    DOI 10.2174/1566523034578438, PubMed 12653404

Publications 2002

  1. Prasmickaite L, Høgset A, Selbo PK, Engesaeter BØ, Hellum M, Berg K (2002)
    Photochemical disruption of endocytic vesicles before delivery of drugs: a new strategy for cancer therapy
    Br J Cancer, 86 (4), 652-7
    DOI 10.1038/sj.bjc.6600138, PubMed 11870551
  2. Selbo PK, Høgset A, Prasmickaite L, Berg K (2002)
    Photochemical internalisation: a novel drug delivery system
    Tumour Biol, 23 (2), 103-12
    DOI 10.1159/000059713, PubMed 12065848

Publications 2001

  1. Selbo PK, Kaalhus O, Sivam G, Berg K (2001)
    5-Aminolevulinic acid-based photochemical internalization of the immunotoxin MOC31-gelonin generates synergistic cytotoxic effects in vitro
    Photochem Photobiol, 74 (2), 303-10
    DOI 10.1562/0031-8655(2001)074<0303:aabpio>2.0.co;2, PubMed 11547569
  2. Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2001)
    In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy
    Int J Cancer, 92 (5), 761-6
    DOI 10.1002/1097-0215(20010601)92:5<761::aid-ijc1238>3.0.co;2-4, PubMed 11340584

Publications 2000

  1. Selbo PK, Sandvig K, Kirveliene V, Berg K (2000)
    Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization
    Biochim Biophys Acta, 1475 (3), 307-13
    DOI 10.1016/s0304-4165(00)00082-9, PubMed 10913830
  2. Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2000)
    Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
    Int J Cancer, 87 (6), 853-9
    DOI 10.1002/1097-0215(20000915)87:6<853::aid-ijc15>3.0.co;2-0, PubMed 10956397

Publications 1999

  1. Berg K, Selbo PK, Prasmickaite L, Tjelle TE, Sandvig K, Moan J, Gaudernack G, Fodstad O, Kjølsrud S, Anholt H, Rodal GH, Rodal SK, Høgset A (1999)
    Photochemical internalization: a novel technology for delivery of macromolecules into cytosol
    Cancer Res, 59 (6), 1180-3
    PubMed 10096543

Publications 1997

  1. Gaullier JM, Berg K, Peng Q, Anholt H, Selbo PK, Ma LW, Moan J (1997)
    Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture
    Cancer Res, 57 (8), 1481-6
    PubMed 9108449

Publications 1996

  1. Andersen S, Bjermer L, Selbo PK, Dalaker M, Johansen B (1996)
    Extracellular phospholipase A2 expression in sarcoidosis
    Sarcoidosis Vasc Diffuse Lung Dis, 13 (1), 70-6
    PubMed 8865415
 
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