Are Martin Holm
- Consultant pulmonologist and associate university professor; MD, PhD
- +47 23072029
Main focus area: Airway inflammation in general and lung transplantation
Curriculum vitae
EDUCATION/EMPLOYMENT: MEDICAL
1993: Cand.med. (MD) Freiburg, Germany
1994: Physician authorisation
1994-2000: Gen.internal medicine: Aker University Hospital, Bærum Hospital, Rikshospitalet University Hospital (Section of Clinical Immunology and Infectious Diseases, Medical Department, Department of Respiratory Medicine)
2000-2004: Research fellow Research Institute for Internal Medicine, Rikshospitalet
2004-2009: Physician Dept. Respiratory Medicine, Rikshospitalet. Main area: lung transplantation
2006: Clinical speciality General Internal Medicine approved
2009- Associate professor medical faculty, University of Oslo and Physician Dept. Respiratory Medicine, Rikshospitalet. Main area: lung transplantation and pulmonary immunology
SCIENTIFICAL MERIT
1998: Bed-side teaching of medical students at Section of Infectious Diseases, Ullevål University Hospital (6 months)
2006: Dr.med. (PhD) thesis, title: "T cell dysfunction in Common Variable Immunodeficiency"
Review and scientific education
Reviewed papers in Blood, Br J Haematol, Clin Exp Immunol, Hematologica, Immunobiology, Immunology, Allergol&Immunopatol.
Reviewed grant applications for Primary Immunodeficiency Association, UK
Publications 2020
Lung allocation for transplant: The European perspective
Clin Transplant, 34 (7), e13883
DOI 10.1111/ctr.13883, PubMed 32294267
Publications 2018
The Role of Airway Inflammation and Bronchial Hyperresponsiveness in Athlete's Asthma
Med Sci Sports Exerc, 50 (4), 659-666
DOI 10.1249/MSS.0000000000001478, PubMed 29189668
Publications 2017
Increased long-term mortality after survival of invasive pneumococcal disease: a population-based study
Infect Dis (Lond), 49 (5), 365-372
DOI 10.1080/23744235.2016.1271997, PubMed 28095723
VII Scandinavian Copd Research Symposium, Holmenkollen, Oslo 18th-19th November 2016
EUR. CLIN. RESPIR. J., 5 1, 1401867
DOI 10.1080/20018525.2017.1401867
An association of particulate air pollution and traffic exposure with mortality after lung transplantation in Europe
Eur Respir J, 49 (1)
DOI 10.1183/13993003.00484-2016, PubMed 27836956
Publications 2016
Differences in Symptom Burden Among Patients With Moderate, Severe, or Very Severe Chronic Obstructive Pulmonary Disease
J Pain Symptom Manage, 51 (5), 849-59
DOI 10.1016/j.jpainsymman.2015.12.324, PubMed 26899820
Occurrence, Characteristics, and Predictors of Pain in Patients with Chronic Obstructive Pulmonary Disease
Pain Manag Nurs, 17 (2), 107-18
DOI 10.1016/j.pmn.2016.01.002, PubMed 27095390
Distinct symptom experiences in subgroups of patients with COPD
Int J Chron Obstruct Pulmon Dis, 11, 1801-9
DOI 10.2147/COPD.S105299, PubMed 27536092
Long-term persistence of human donor alveolar macrophages in lung transplant recipients
Thorax, 71 (11), 1006-1011
DOI 10.1136/thoraxjnl-2016-208292, PubMed 27329043
Dichotomy in pulmonary graft-versus-host disease evident among allogeneic stem-cell transplant recipients undergoing lung transplantation
Eur Respir J, 48 (6), 1807-1810
DOI 10.1183/13993003.01121-2016, PubMed 27587560
A unique set of 6 circulating microRNAs for early detection of non-small cell lung cancer
Oncotarget, 7 (24), 37250-37259
DOI 10.18632/oncotarget.9363, PubMed 27191990
Publications 2013
Multiorgan procurement increases systemic inflammation in brain dead donors
Clin Transplant, 27 (4), 613-8
DOI 10.1111/ctr.12175, PubMed 23803161
Lung disease, T-cells and inflammation in common variable immunodeficiency disorders
Scand J Clin Lab Invest, 73 (6), 514-22
DOI 10.3109/00365513.2013.819523, PubMed 23957371
Lung transplantation for bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation: unresolved questions
Transplantation, 96 (4), e21-2
DOI 10.1097/TP.0b013e31829df2c0, PubMed 23958883
Publications 2012
Lung transplantation for bronchiolitis obliterans syndrome after allo-SCT
Bone Marrow Transplant, 48 (5), 703-7
DOI 10.1038/bmt.2012.197, PubMed 23064037
Publications 2010
Development of pulmonary abnormalities in patients with common variable immunodeficiency: associations with clinical and immunologic factors
Ann Allergy Asthma Immunol, 104 (6), 503-10
DOI 10.1016/j.anai.2010.04.015, PubMed 20568383
Publications 2009
Chemokines and common variable immunodeficiency; possible contribution of CCL19, CCL21 and CCR7 to immune dysregulation
Clin Exp Immunol, 158 (2), 237-45
DOI 10.1111/j.1365-2249.2009.04013.x, PubMed 19747210
Publications 2008
Increased expression of LIGHT/TNFSF14 and its receptors in experimental and clinical heart failure
Eur J Heart Fail, 10 (4), 352-9
DOI 10.1016/j.ejheart.2008.02.010, PubMed 18353719
Chemokines and common variable immunodeficiency; possible contribution of the fractalkine system (CX3CL1/CX3CR1) to chronic inflammation
Clin Immunol, 130 (2), 151-61
DOI 10.1016/j.clim.2008.09.002, PubMed 18938112
Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes
Blood, 113 (9), 1967-76
DOI 10.1182/blood-2008-02-141937, PubMed 18981294
Publications 2007
Low numbers of regulatory T cells in common variable immunodeficiency: association with chronic inflammation in vivo
Clin Exp Immunol, 147 (3), 521-5
DOI 10.1111/j.1365-2249.2006.03314.x, PubMed 17302902
Publications 2006
Polyclonal expansion of large granular lymphocytes in common variable immunodeficiency - association with neutropenia
Clin Exp Immunol, 144 (3), 418-24
DOI 10.1111/j.1365-2249.2006.03086.x, PubMed 16734610
Publications 2005
Common variable immunodeficiency and the complement system; low mannose-binding lectin levels are associated with bronchiectasis
Clin Exp Immunol, 142 (3), 576-84
DOI 10.1111/j.1365-2249.2005.02951.x, PubMed 16297171
T cell dysfunction in common variable immunodeficiency
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 385, 1 b. (flere pag.)
BIBSYS 060457058, ISBN 82-8072-838-4
Publications 2004
Stimulation of toll-like receptor 2 in mononuclear cells from HIV-infected patients induces chemokine responses: possible pathogenic consequences
Clin Exp Immunol, 138 (1), 116-21
DOI 10.1111/j.1365-2249.2004.02595.x, PubMed 15373913
Abnormal interleukin-7 function in common variable immunodeficiency
Blood, 105 (7), 2887-90
DOI 10.1182/blood-2004-06-2423, PubMed 15598813
Gene expression analysis of peripheral T cells in a subgroup of common variable immunodeficiency shows predominance of CCR7(-) effector-memory T cells
Clin Exp Immunol, 138 (2), 278-89
DOI 10.1111/j.1365-2249.2004.02630.x, PubMed 15498038
ICOS deficiency in patients with common variable immunodeficiency
Clin Immunol, 113 (3), 234-40
DOI 10.1016/j.clim.2004.07.002, PubMed 15507387
Publications 2003
Impaired secretion of IL-10 by T cells from patients with common variable immunodeficiency--involvement of protein kinase A type I
J Immunol, 170 (11), 5772-7
DOI 10.4049/jimmunol.170.11.5772, PubMed 12759461
Hydroxymethylglutaryl coenzyme a reductase inhibitors down-regulate chemokines and chemokine receptors in patients with coronary artery disease
J Am Coll Cardiol, 41 (9), 1460-7
DOI 10.1016/s0735-1097(03)00263-8, PubMed 12742282
Hydroxymethylglutaryl coenzyme a reductase inhibitors down-regulate chemokines and chemokine receptors in patients with coronary artery disease
In Journal of the American College of Cardiology, Elsevier, New York, 41(2003)9, s.1460-7
BIBSYS 041728793
Enhanced expression of inflammatory cytokines and activation markers in T-cells from patients with chronic heart failure
Cardiovasc Res, 60 (1), 141-6
DOI 10.1016/s0008-6363(03)00362-6, PubMed 14522416
Publications 2002
Stromal cell-derived factor-1alpha in unstable angina: potential antiinflammatory and matrix-stabilizing effects
Circulation, 106 (1), 36-42
DOI 10.1161/01.cir.0000020001.09990.90, PubMed 12093767
Occurence and clinical presentation of systemic pneumococcal infections in an unselected population in Oslo, Norway, between 1993 and 1997
In European journal of clinical microbiology & infectious diseases, Vieweg, Wiesbaden, 21(2002)nr 6, s. 465-467
BIBSYS 031275397
Occurrence and clinical presentation of systemic pneumococcal infections in an unselected population in Oslo, Norway, between 1993 and 1997
Eur J Clin Microbiol Infect Dis, 21 (6), 465-7
DOI 10.1007/s10096-002-0751-z, PubMed 12111604
Publications 1997
[Pneumococcal endocarditis of the tricuspid valve. A case report with review of the literature]
Tidsskr Nor Laegeforen, 117 (6), 815-7
PubMed 9102976