Liv Ingunn Bjoner Sikkeland

  • Senior engineer; PhD, MSc
  • +47 23072997
Main focus area: Molecular biology
 

Publications 2024

Ellingsen DG, Sikkeland LIB, Lund MB, Skaugset NP, Ulvestad B (2024)
A study of inflammatory biomarkers in crystalline silica exposed rock drillers
Int Arch Occup Environ Health, 97 (5), 587-595
DOI 10.1007/s00420-024-02070-2, PubMed 38702427

Publications 2023

Mangseth H, Sikkeland LIB, Durheim MT, Ulvestad M, Myrdal OH, Kongerud J, Lund MB (2023)
Comparison of different reference values for lung function: implications of inconsistent use among centers
BMC Pulm Med, 23 (1), 137
DOI 10.1186/s12890-023-02430-7, PubMed 37095462

Sikkeland LIB, Ueland T, Lund MB, Durheim MT, Mollnes TE (2023)
A role for the terminal C5-C9 complement pathway in idiopathic pulmonary fibrosis
Front Med (Lausanne), 10, 1236495
DOI 10.3389/fmed.2023.1236495, PubMed 37621463

Publications 2022

Ellingsen DG, Ulvestad B, Lund MB, Skaugset NP, Sikkeland LIB (2022)
A study of pneumoproteins in crystalline silica exposed rock drillers
Inhal Toxicol, 34 (3-4), 99-105
DOI 10.1080/08958378.2022.2048745, PubMed 35286186

Publications 2021

Das J, Idh N, Sikkeland LIB, Paues J, Lerm M (2021)
DNA methylome-based validation of induced sputum as an effective protocol to study lung immunity: construction of a classifier of pulmonary cell types
Epigenetics, 17 (8), 882-893
DOI 10.1080/15592294.2021.1969499, PubMed 34482796

Myrdal OH, Aaløkken TM, Diep PP, Ruud E, Brinch L, Fosså K, Mangseth H, Kongerud J, Sikkeland LI, Lund MB (2021)
Late-Onset, Noninfectious Pulmonary Complications following Allogeneic Hematopoietic Stem Cell Transplantation: A Nationwide Cohort Study of Long-Term Survivors
Respiration, 101 (6), 544-552
DOI 10.1159/000520824, PubMed 34937032

Sikkeland LIB, Durheim MT, Riste TB, Kongerud J, Alexis NE, Holm AM (2021)
Relation of sputum neutrophilia to the development of chronic lung allograft dysfunction after lung transplantation
Clin Transplant, 35 (3), e14188
DOI 10.1111/ctr.14188, PubMed 33315265

Sikkeland LIB, Qiao SW, Ueland T, Myrdal O, Wyrożemski Ł, Aukrust P, Jahnsen FL, Sjåheim T, Kongerud J, Molberg Ø, Lund MB, Bækkevold ES (2021)
Lung CD4+ T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-γ
Eur Respir J, 57 (3)
DOI 10.1183/13993003.00983-2020, PubMed 33154027

Publications 2020

Myrdal OH, Diep PP, Ruud E, Brinch L, Massey RJ, Edvardsen E, Kongerud J, Lund MB, Sikkeland LI (2020)
Determinants of cardiorespiratory fitness in very long-term survivors of allogeneic hematopoietic stem cell transplantation: a national cohort study
Support Care Cancer, 29 (4), 1959-1967
DOI 10.1007/s00520-020-05644-1, PubMed 32827056

Publications 2019

Heldal KK, Austigard ÅD, Svendsen KH, Einarsdottir E, Goffeng LO, Sikkeland LI, Nordby KC (2019)
Endotoxin and Hydrogen Sulphide Exposure and Effects on the Airways Among Waste Water Workers in Sewage Treatment Plants and Sewer Net System
Ann Work Expo Health, 63 (4), 437-447
DOI 10.1093/annweh/wxz020, PubMed 30938763

Kononova N, Sikkeland LIB, Mahmood F, Vistnes M, Kongerud J, Einvik G, Søyseth V (2019)
Annual decline in forced expiratory volume and airway inflammatory cells and mediators in a general population-based sample
BMC Pulm Med, 19 (1), 90
DOI 10.1186/s12890-018-0765-7, PubMed 31072364

Publications 2018

Bølling AK, Steensen TB, Alexis NE, Sikkeland LIB (2018)
Isolating and culturing of sputum macrophages: A potential ex vivo/in vitro model
Exp Lung Res, 44 (6), 312-322
DOI 10.1080/01902148.2018.1539788, PubMed 30465455

Myrdal OH, Kanellopoulos A, Christensen JR, Ruud E, Edvardsen E, Kongerud J, Sikkeland LI, Lund MB (2018)
Risk factors for impaired pulmonary function and cardiorespiratory fitness in very long-term adult survivors of childhood acute lymphoblastic leukemia after treatment with chemotherapy only
Acta Oncol, 57 (5), 658-664
DOI 10.1080/0284186X.2017.1423177, PubMed 29303026

Sikkeland LIB, Borander AK, Voie ØA, Aass HCD, Øvstebø R, Aukrust P, Longva K, Alexis NE, Kongerud J, Ueland T (2018)
Systemic and Airway Inflammation after Exposure to Fumes from Military Small Arms
Am J Respir Crit Care Med, 197 (10), 1349-1353
DOI 10.1164/rccm.201709-1857LE, PubMed 29144885

Stang J, Sikkeland LIB, Tufvesson E, Holm AM, Stensrud T, Carlsen KH (2018)
The Role of Airway Inflammation and Bronchial Hyperresponsiveness in Athlete's Asthma
Med Sci Sports Exerc, 50 (4), 659-666
DOI 10.1249/MSS.0000000000001478, PubMed 29189668

Publications 2017

Borander AK, Voie ØA, Longva K, Danielsen TE, Grahnstedt S, Sandvik L, Kongerud J, Sikkeland LIB (2017)
Military small arms fire in association with acute decrements in lung function
Occup Environ Med, 74 (9), 639-644
DOI 10.1136/oemed-2016-104207, PubMed 28408655

Publications 2016

Eguíluz-Gracia I, Schultz HH, Sikkeland LI, Danilova E, Holm AM, Pronk CJ, Agace WW, Iversen M, Andersen C, Jahnsen FL, Baekkevold ES (2016)
Long-term persistence of human donor alveolar macrophages in lung transplant recipients
Thorax, 71 (11), 1006-1011
DOI 10.1136/thoraxjnl-2016-208292, PubMed 27329043

Sikkeland LI, Johnsen HL, Riste TB, Alexis NE, Halvorsen B, Søyseth V, Kongerud J (2016)
Sputum neutrophils are elevated in smelter workers, and systemic neutrophils are associated with rapid decline in FEV1
Occup Environ Med, 73 (7), 459-66
DOI 10.1136/oemed-2015-103083, PubMed 27052769

Publications 2015

Nemer M, Sikkeland LI, Kasem M, Kristensen P, Nijem K, Bjertness E, Skare Ø, Bakke B, Kongerud J, Skogstad M (2015)
Airway inflammation and ammonia exposure among female Palestinian hairdressers: a cross-sectional study
Occup Environ Med, 72 (6), 428-34
DOI 10.1136/oemed-2014-102437, PubMed 25653315

Publications 2014

Sikkeland LIB, Lund MB, Kongerud JS (2014)
Immunological Analysis of Induced Sputum in Work Exposures
JEIT, 1 (4), 183-189
DOI 10.7178/jeit.10, PublikaID 207

Voie Ø, Borander AK, Sikkeland LI, Grahnstedt S, Johnsen A, Danielsen TE, Longva K, Kongerud J (2014)
Health effects after firing small arms comparing leaded and unleaded ammunition
Inhal Toxicol, 26 (14), 873-9
DOI 10.3109/08958378.2014.970783, PubMed 25373830

Publications 2013

Gregersen S, Holm AM, Fevang B, Ueland T, Sikkeland LI, Aaløkken TM, Mynarek G, Kongerud J, Aukrust P, Johansen B, Frøland SS (2013)
Lung disease, T-cells and inflammation in common variable immunodeficiency disorders
Scand J Clin Lab Invest, 73 (6), 514-22
DOI 10.3109/00365513.2013.819523, PubMed 23957371

Publications 2012

Sikkeland LI, Dahl CP, Ueland T, Andreassen AK, Gude E, Edvardsen T, Holm T, Yndestad A, Gullestad L, Kongerud J, Aukrust P, Øie E (2012)
Increased levels of inflammatory cytokines and endothelin-1 in alveolar macrophages from patients with chronic heart failure
PLoS One, 7 (5), e36815
DOI 10.1371/journal.pone.0036815, PubMed 22615818

Sikkeland LI, Eduard W, Skogstad M, Alexis NE, Kongerud J (2012)
Recovery from workplace-induced airway inflammation 1 year after cessation of exposure
Occup Environ Med, 69 (10), 721-6
DOI 10.1136/oemed-2011-100632, PubMed 22833663

Publications 2011

Skogstad M, Sikkeland LI, Øvstebø R, Haug KB, Heldal KK, Skare Ø, Kongerud J, Kierulf P, Eduard W (2011)
Long-term occupational outcomes of endotoxin exposure and the effect of exposure cessation
Occup Environ Med, 69 (2), 107-12
DOI 10.1136/oem.2010.062414, PubMed 21810928

Publications 2010

Øie E, Ahmed MS, Ueland T, Sikkeland LI, Dahl CP, Hagelin EM, von Lueder T, Edvardsen T, Andreassen AK, Gullestad L, Aukrust P, Yndestad A, Vinge LE, Attramadal H (2010)
Adrenomedullin is increased in alveolar macrophages and released from the lungs into the circulation in severe heart failure
Basic Res Cardiol, 105 (1), 89-98
DOI 10.1007/s00395-009-0070-y, PubMed 19823891

Publications 2009

Fell AK, Sikkeland LI, Svendsen MV, Kongerud J (2009)
Airway inflammation in cement production workers
Occup Environ Med, 67 (6), 395-400
DOI 10.1136/oem.2009.047852, PubMed 19854695

Sikkeland LI, Eduard W, Stangeland AM, Thorgersen EB, Haug T, Aukrust P, Halvorsen B, Mollnes TE, Kongerud J (2009)
Occupational exposure to bacterial single cell protein induces inflammation in lung and blood
Inhal Toxicol, 21 (8), 674-81
DOI 10.1080/08958370802491425, PubMed 19558225

Publications 2008

Sikkeland LIB (2008)
Inflammatory biomarkers after occupational exposure to micro-organisms
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 666, 1 b. (flere pag.)
BIBSYS 082426716, ISBN 978-82-8072-749-7

Publications 2007

Sikkeland LI, Haug T, Stangeland AM, Flatberg G, Søstrand P, Halvorsen B, Kongerud J (2007)
Airway inflammation in paper mill workers
J Occup Environ Med, 49 (10), 1135-42
DOI 10.1097/JOM.0b013e31814b2e87, PubMed 18000418

Sikkeland LI, Kongerud J, Stangeland AM, Haug T, Alexis NE (2007)
Macrophage enrichment from induced sputum
Thorax, 62 (6), 558-9
DOI 10.1136/thx.2006.073544, PubMed 17536036

Sikkeland LI, Skogstad M, Ovstebø R, Brusletto B, Haug KB, Kongerud J, Eduard W, Kierulf P (2007)
Circulating lipopolysaccharides in the blood from "bioprotein" production workers
Occup Environ Med, 65 (3), 211-4
DOI 10.1136/oem.2007.032938, PubMed 17855504

Sikkeland LI, Thorgersen EB, Haug T, Mollnes TE (2007)
Complement activation and cytokine response by BioProtein, a bacterial single cell protein
Clin Exp Immunol, 148 (1), 146-52
DOI 10.1111/j.1365-2249.2007.03339.x, PubMed 17302729

Publications 2005

Munkeby BH, Børke WB, Bjørnland K, Sikkeland LI, Borge GI, Lømo J, Rivera S, Khrestchatisky M, Halvorsen B, Saugstad OD (2005)
Resuscitation of hypoxic piglets with 100% O2 increases pulmonary metalloproteinases and IL-8
Pediatr Res, 58 (3), 542-8
DOI 10.1203/01.PDR.0000179407.46810.2D, PubMed 16148071

Publications 2004

Munkeby BH, Børke WB, Bjørnland K, Sikkeland LI, Borge GI, Halvorsen B, Saugstad OD (2004)
Resuscitation with 100% O2 increases cerebral injury in hypoxemic piglets
Pediatr Res, 56 (5), 783-90
DOI 10.1203/01.PDR.0000141988.89820.E3, PubMed 15347772

Publications 2003

Grønevik E, Tollefsen S, Sikkeland LIB, Haug T, Tjelle TE, Mathiesen I (2003)
DNA transfection of mononuclear cells in muscle tissue
J Gene Med, 5 (10), 909-917
DOI 10.1002/jgm.416, PubMed 14533200

Ueland T, Sikkeland LI, Yndestad A, Eiken HG, Holm T, Guevara C, Haug T, Endresen K, Frøland SS, Gullestad L, Andreassen AK, Geiran O, Simonsen S, Aukrust P (2003)
Myocardial gene expression of inflammatory cytokines after heart transplantation in relation to the development of transplant coronary artery disease
Am J Cardiol, 92 (6), 715-7
DOI 10.1016/s0002-9149(03)00836-1, PubMed 12972116

Publications 2002

Stylianou E, Yndestad A, Sikkeland LI, Bjerkeli V, Damås JK, Haug T, Eiken HG, Aukrust P, Frøland SS (2002)
Effects of interferon-alpha on gene expression of chemokines and members of the tumour necrosis factor superfamily in HIV-infected patients
Clin Exp Immunol, 130 (2), 279-85
DOI 10.1046/j.1365-2249.2002.01980.x, PubMed 12390316