Marit Helen Andersen

  • Professor II PhD
  • +47 23 07 00 00

Patient-reported outcomes following living donor nephrectomy

Kidney transplantation is the optimal treatment for patients with end stage renal disease. In Norway almost 40 % of all renal transplants are performed with organs from living donors, and efforts are made to increase the number of kidneys available for transplantation. The purpose of this thesis was to study clinical and patient-reported outcomes following living kidney donor nephrectomy, with particular emphasis on patient-reported outcomes. A combination of quantitative and qualitative research approaches was used. In a randomized, controlled trial of 122 donors we compared laparoscopic and open donor nephrectomy, focusing on donor safety, postoperative pain, sick leave, health status and overall quality of life at 1, 6 and 12 months follow-up. To explore donor experiences of going through surgery 12 donors were in-depth interviewed at one week and at one year after open donor nephrectomy.

The results from the randomized trial demonstrated that the conventional open donor nephrectomy was superior to laparoscopic donor nephrectomy with regard to donor safety. Yet, an uncomplicated laparoscopic donor nephrectomy had important short-term advantages such as less analgesic requirements, less postoperative pain, shorter sick leave, and better health status and as compared to the open approach. Long-term follow up revealed significant differences in favour of laparoscopy only when adjusting for reoperations and convertions. We therefore conclude that long term benefits are hard to prove in favour of the laparoscopic technique. The in-depth interviews revealed that a positive feeling about being a donor was the dominant theme in both interview series. Though experiencing disincentives from surgery during the first postoperative period, the donors expressed that they were back to their normal health at one year after surgery. Donors experiencing unsuccessful recipient outcome did not regret donation.


Publications not indexed by PubMed:

Dueland, Svein; Line, Pål Dag; Hagness, Morten; Foss, Aksel; Andersen, Marit Helen.
Long‐term quality of life after liver transplantation for non‐resectable colorectal metastases confined to the liver.
JBJS Open Access 2018 s. -
OUS UiO

Haraldstad, Kristin; Wahl, Astrid Klopstad; Andenæs, Randi; Andersen, John Roger; Andersen, Marit Helen; Elisabeth Grov, Beisland; Råheim Borge, Christine; Engebretsen, Eivind; Eisemann, Martin; Halvorsrud, Liv Torill; Hanssen, Tove Aminda; Haugstvedt, Anne; Haugland, Trude; Johansen, Venke A; Løvereide, Lise; Larsen, Marie Hamilton; Løyland, Borghild; Kvarme, Lisbeth Gravdal; Moons, Philip; Norekvål, Tone M.; Ribu, Lis; Urstad, Kristin Hjorthaug; Rohde, Gudrun Elin; Helseth, Sølvi.
A systematic snapshot review of quality of life research in medicine and health sciences.
Internasjonal livskvalitetskonferanse, ISOQOL; 2018-10-24 - 2018-10-28.

Engebretsen, Eivind; Andersen, Marit Helen; Urstad, Kristin Hjorthaug; Wahl, Astrid Klopstad.
Action Research in Implementation and Evaluation. Outline of a Study of a Training Programme for Kidney Transplant Recipients. I: Theory and Methodology in International Comparative Classroom Studies.
Cappelen Damm Akademisk 2014 ISBN 978–82-02–47061–6. s. 256-266.

Foss, Aksel; Andersen, Marit Helen; Hagness, Morten; Vidnes, Tone Karine; Finstad, Ellen Drolsum; Wahl, Astrid Klopstad; Dueland, Svein.
Patient Survival and Quality of Life Following Liver Transplantation for Colorectal Liver Metastases.
Liver transplantation 2010 ;Volum 16.(6) s. S189-S190.


Indexed by PubMed:

 

Publications 2019

Andersen MH, Wahl AK, Engebretsen E, Urstad KH (2019)
Implementing a tailored education programme: renal transplant recipients' experiences
J Ren Care, 45 (2), 111-119
DOI 10.1111/jorc.12273, PubMed 30920177

Engeseth M, Enden T, Andersen MH, Sandset PM, Wik HS (2019)
Does the Villalta scale capture the essence of postthrombotic syndrome? A qualitative study of patient experience and expert opinion
J Thromb Haemost
DOI 10.1111/jth.14557, PubMed 31265193

Gustavsen MT, Midtvedt K, Lønning K, Jacobsen T, Reisaeter AV, De Geest S, Andersen MH, Hartmann A, Åsberg A (2019)
Evaluation of tools for annual capture of adherence to immunosuppressive medications after renal transplantation - a single-centre open prospective trial
Transpl Int, 32 (6), 614-625
DOI 10.1111/tri.13412, PubMed 30770608

Hausken J, Fretland ÅA, Edwin B, Andersen MH, Dagenborg VJ, Bjørnelv GMW, Kristiansen R, Røysland K, Kvarstein G, Tønnessen TI (2019)
Intravenous Patient-controlled Analgesia Versus Thoracic Epidural Analgesia After Open Liver Surgery: A Prospective, Randomized, Controlled, Noninferiority Trial
Ann Surg, 270 (2), 193-199
DOI 10.1097/SLA.0000000000003209, PubMed 30676382

Hjørnholm U, Larstorp ACK, Andersen MH, Høieggen A (2019)
Directly observed therapy prior to ambulatory blood pressure measurement (DOT-HTN) in uncontrolled hypertensive patients - Effect on blood pressure, safety and patient perception
Blood Press
DOI 10.1080/08037051.2019.1633907, PubMed 31250668

Publications 2018

Andresen B, Døhlen G, Diep LM, Lindberg H, Fosse E, Andersen MH (2018)
Psychosocial and clinical outcomes of percutaneous versus surgical pulmonary valve implantation
Open Heart, 5 (1), e000758
DOI 10.1136/openhrt-2017-000758, PubMed 30018768

Bøe C, Bondevik H, Wahl AK, Andersen MH (2018)
Going through laparoscopic liver resection in patients with colorectal liver metastases-A qualitative study
Nurs Open, 6 (2), 260-267
DOI 10.1002/nop2.206, PubMed 30918677

Fretland ÅA, Dagenborg VJ, Bjørnelv GMW, Kazaryan AM, Kristiansen R, Fagerland MW, Hausken J, Tønnessen TI, Abildgaard A, Barkhatov L, Yaqub S, Røsok BI, Bjørnbeth BA, Andersen MH, Flatmark K, Aas E, Edwin B (2018)
Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial
Ann Surg, 267 (2), 199-207
DOI 10.1097/SLA.0000000000002353, PubMed 28657937

Lillehagen I, Andersen MH, Urstad KH, Wahl A, Engebretsen E (2018)
How does a new patient education programme for renal recipients become situated and adapted when implemented in the daily teaching practice in a university hospital? An ethnographic observation study
BMJ Open, 8 (11), e023005
DOI 10.1136/bmjopen-2018-023005, PubMed 30478114

Lønning K, Heldal K, Bernklev T, Brunborg C, Andersen MH, von der Lippe N, Reisæter AV, Line PD, Hartmann A, Midtvedt K (2018)
Improved Health-Related Quality of Life in Older Kidney Recipients 1 Year After Transplantation
Transplant Direct, 4 (4), e351
DOI 10.1097/TXD.0000000000000770, PubMed 29707622

Lønning K, Midtvedt K, Bernklev T, Brunborg C, Andersen MH, von der Lippe N, Reisaeter AV, Line PD, Hartmann A, Heldal K (2018)
Changes in health-related quality of life in older candidates waiting for kidney transplantation
Nephrology (Carlton), 23 (10), 948-956
DOI 10.1111/nep.13117, PubMed 28734131

Lønning K, Midtvedt K, Heldal K, Andersen MH (2018)
Older kidney transplantation candidates' expectations of improvement in life and health following kidney transplantation: semistructured interviews with enlisted dialysis patients aged 65 years and older
BMJ Open, 8 (6), e021275
DOI 10.1136/bmjopen-2017-021275, PubMed 29934388

Urstad KH, Wahl AK, Engebretsen E, Larsen MH, Vidnes TK, Stenwig AGK, Simensen ØW, Nordli A, Reisaeter AV, Andersen MH (2018)
Implementation of a new patient education programme for renal transplant recipients
J Ren Care, 44 (2), 106-114
DOI 10.1111/jorc.12236, PubMed 29460501

Verket NJ, Andersen MH, Sandvik L, Tanbo TG, Qvigstad E (2018)
Lack of cross-cultural validity of the Endometriosis Health Profile-30
J Endometr Pelvic Pain Disord, 10 (2), 107-115
DOI 10.1177/2284026518780638, PubMed 30320042

Verket NJ, Uhlig T, Sandvik L, Andersen MH, Tanbo TG, Qvigstad E (2018)
Health-related quality of life in women with endometriosis, compared with the general population and women with rheumatoid arthritis
Acta Obstet Gynecol Scand, 97 (11), 1339-1348
DOI 10.1111/aogs.13427, PubMed 30007080

Publications 2017

Andresen B, Mishra V, Lewandowska M, Andersen JG, Andersen MH, Lindberg H, Døhlen G, Fosse E (2017)
In-hospital cost comparison between percutaneous pulmonary valve implantation and surgery
Eur J Cardiothorac Surg, 51 (4), 747-753
DOI 10.1093/ejcts/ezw378, PubMed 28007875

Lillehol BM, Lønning K, Andersen MH (2017)
Exploring nurse managers' perception of using the RAFAELA system as a management tool in a Norwegian hospital setting
Nurs Open, 5 (1), 77-83
DOI 10.1002/nop2.115, PubMed 29344398

Meyer KB, Bjørk IT, Wahl AK, Lennerling A, Andersen MH (2017)
Long-term experiences of Norwegian live kidney donors: qualitative in-depth interviews
BMJ Open, 7 (2), e014072
DOI 10.1136/bmjopen-2016-014072, PubMed 28209606

Meyer KB, Hartmann A, Mjøen G, Andersen MH (2017)
Relationships Between Clinical, Self-Reported, and Donation Specific Outcomes: A Prospective Follow-up Study 10 Years After Kidney Donation
Ann Transplant, 22, 148-155
DOI 10.12659/aot.902330, PubMed 28321111

Syversen TB, Sørensen DW, Foss S, Andersen MH (2017)
Donation after circulatory death - an expanded opportunity for donation appreciated by families
J Crit Care, 43, 306-311
DOI 10.1016/j.jcrc.2017.09.002, PubMed 28968526

Publications 2016

Andersen MH, Lønning K, Bjørnelv GM, Fagerström L (2016)
Nursing intensity and costs of nurse staffing demonstrated by the RAFAELA system: liver vs. kidney transplant recipients
J Nurs Manag, 24 (6), 798-805
DOI 10.1111/jonm.12384, PubMed 27162168

Meyer K, Wahl AK, Bjørk IT, Wisløff T, Hartmann A, Andersen MH (2016)
Long-term, self-reported health outcomes in kidney donors
BMC Nephrol, 17, 8
DOI 10.1186/s12882-016-0221-y, PubMed 26754798

Publications 2015

Fretland ÅA, Kazaryan AM, Bjørnbeth BA, Flatmark K, Andersen MH, Tønnessen TI, Bjørnelv GM, Fagerland MW, Kristiansen R, Øyri K, Edwin B (2015)
Open versus laparoscopic liver resection for colorectal liver metastases (the Oslo-CoMet Study): study protocol for a randomized controlled trial
Trials, 16, 73
DOI 10.1186/s13063-015-0577-5, PubMed 25872027

Hustad NB, Hellesøe R, Andersen MH (2015)
A qualitative study of manager experiences using the RAFAELA system
Open Journal of Nursing, 5, 1224-1232
DOI 10.4236/ojn.2015.511109, PublikaID 225

Publications 2014

Andersen MH, Lønning Kjersti, Fagerstrøm Lisbeth (2014)
Testing reliability and validity of the Oulu Patient Classification instrument- the first step in evaluating the RAFAELA system in Norway
OJN, 4, 303-311
DOI 10.4236/ojn.2014.44035, PublikaID 210

Andresen B, Andersen MH, Lindberg H, Døhlen G, Fosse E (2014)
Perceived health after percutaneous pulmonary valve implantation: in-depth interviews of patients and next-of-kin
BMJ Open, 4 (7), e005102
DOI 10.1136/bmjopen-2014-005102, PubMed 25079930

Fagerström L, Lønning K, Andersen MH (2014)
The RAFAELA system: a workforce planning tool for nurse staffing and human resource management
Nurs Manag (Harrow), 21 (2), 30-6
DOI 10.7748/nm2014.04.21.2.30.e1199, PubMed 24779764

Publications 2012

Andersen MH, Dueland S, Hagness M, Vidnes T, Finstad ED, Wahl AK, Foss A (2012)
Quality of life following liver transplantation in patients with liver metastases from colorectal carcinoma
Scand J Caring Sci, 26 (4), 713-9
DOI 10.1111/j.1471-6712.2012.00984.x, PubMed 22452269

Urstad KH, Wahl AK, Andersen MH, Øyen O, Fagermoen MS (2012)
Renal recipients' educational experiences in the early post-operative phase--a qualitative study
Scand J Caring Sci, 26 (4), 635-42
DOI 10.1111/j.1471-6712.2012.00972.x, PubMed 22417055

Urstad KH, Wahl AK, Andersen MH, Øyen O, Hagen KB (2012)
Limited evidence for the effectiveness of educational interventions for renal transplant recipients. Results from a systematic review of controlled clinical trials
Patient Educ Couns, 90 (2), 147-54
DOI 10.1016/j.pec.2012.10.020, PubMed 23199794

Urstad KH, Øyen O, Andersen MH, Moum T, Wahl AK (2012)
The effect of an educational intervention for renal recipients: a randomized controlled trial
Clin Transplant, 26 (3), E246-53
DOI 10.1111/j.1399-0012.2012.01666.x, PubMed 22686948

Vidnes TK, Wahl AK, Andersen MH (2012)
Patient experiences following liver transplantation due to liver metastases from colorectal cancer
Eur J Oncol Nurs, 17 (3), 269-74
DOI 10.1016/j.ejon.2012.07.004, PubMed 22901549

Publications 2010

Lohne V, Heer HC, Andersen M, Miaskowski C, Kongerud J, Rustøen T (2010)
Qualitative study of pain of patients with chronic obstructive pulmonary disease
Heart Lung, 39 (3), 226-34
DOI 10.1016/j.hrtlng.2009.08.002, PubMed 20457343

Urstad KH, Andersen MH, Øyen O, Moum T, Wahl AK (2010)
Patients' level of knowledge measured five days after kidney transplantation
Clin Transplant, 25 (4), 646-52
DOI 10.1111/j.1399-0012.2010.01355.x, PubMed 21077953

Publications 2009

Hamidi V, Andersen MH, Oyen O, Mathisen L, Fosse E, Kristiansen IS (2009)
Cost effectiveness of open versus laparoscopic living-donor nephrectomy
Transplantation, 87 (6), 831-8
DOI 10.1097/TP.0b013e318199cfc9, PubMed 19300185

Mathisen L, Lingaas PS, Andersen MH, Hol PK, Fredriksen PM, Sundet K, Rokne B, Wahl AK, Fosse E (2009)
Changes in cardiac and cognitive function and self-reported outcomes at one year after coronary artery bypass grafting
J Thorac Cardiovasc Surg, 140 (1), 122-8
DOI 10.1016/j.jtcvs.2009.10.034, PubMed 20018306

Publications 2007

Andersen MH, Bruserud F, Mathisen L, Wahl AK, Hanestad BR, Fosse E (2007)
Follow-up interviews of 12 living kidney donors one yr after open donor nephrectomy
Clin Transplant, 21 (6), 702-9
DOI 10.1111/j.1399-0012.2007.00726.x, PubMed 17988262

Andersen MH, Mathisen L, Veenstra M, Oyen O, Edwin B, Digernes R, Kvarstein G, Tønnessen TI, Wahl AK, Hanestad BR, Fosse E (2007)
Quality of life after randomization to laparoscopic versus open living donor nephrectomy: long-term follow-up
Transplantation, 84 (1), 64-9
DOI 10.1097/01.tp.0000268071.63977.42, PubMed 17627239

Mathisen L, Andersen MH, Veenstra M, Wahl AK, Hanestad BR, Fosse E (2007)
Quality of life can both influence and be an outcome of general health perceptions after heart surgery
Health Qual Life Outcomes, 5, 27
DOI 10.1186/1477-7525-5-27, PubMed 17524152

Publications 2006

Andersen MH, Mathisen L, Oyen O, Edwin B, Digernes R, Kvarstein G, Tønnessen TI, Wahl AK, Hanestad BR, Fosse E (2006)
Postoperative pain and convalescence in living kidney donors-laparoscopic versus open donor nephrectomy: a randomized study
Am J Transplant, 6 (6), 1438-43
DOI 10.1111/j.1600-6143.2006.01301.x, PubMed 16686768

Lingaas PS, Hol PK, Lundblad R, Rein KA, Mathisen L, Smith HJ, Andersen R, Thaulow E, Tønnesen TI, Svennevig JL, Hauge SN, Fredriksen PM, Andersen M, Fosse E (2006)
Clinical and radiologic outcome of off-pump coronary surgery at 12 months follow-up: a prospective randomized trial
Ann Thorac Surg, 81 (6), 2089-95
DOI 10.1016/j.athoracsur.2005.12.003, PubMed 16731135

Publications 2005

Andersen MH, Mathisen L, Øyen O, Wahl AK, Hanestad BR, Fosse E (2005)
Living donors' experiences 1 wk after donating a kidney
Clin Transplant, 19 (1), 90-6
DOI 10.1111/j.1399-0012.2004.00304.x, PubMed 15659140

Mathisen L, Andersen MH, Hol PK, Lingaas PS, Lundblad R, Rein KA, Tønnessen TI, Mørk BE, Svennevig JL, Wahl AK, Hanestad BR, Fosse E (2005)
Patient-reported outcome after randomization to on-pump versus off-pump coronary artery surgery
Ann Thorac Surg, 79 (5), 1584-9
DOI 10.1016/j.athoracsur.2004.10.019, PubMed 15854937

Mathisen L, Andersen MH, Hol PK, Tennøe B, Lund C, Russell D, Lundblad R, Halvorsen S, Wahl AK, Hanestad BR, Fosse E (2005)
Preoperative cerebral ischemic lesions predict physical health status after on-pump coronary artery bypass surgery
J Thorac Cardiovasc Surg, 130 (6), 1691-7
DOI 10.1016/j.jtcvs.2005.08.008, PubMed 16308017

Øyen O, Andersen M, Mathisen L, Kvarstein G, Edwin B, Line PD, Scholz T, Pfeffer PF (2005)
Laparoscopic versus open living-donor nephrectomy: experiences from a prospective, randomized, single-center study focusing on donor safety
Transplantation, 79 (9), 1236-40
DOI 10.1097/01.tp.0000161669.49416.ba, PubMed 15880077

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