Marit Helen Andersen
- Professor II PhD
- +47 23 07 00 00
Patient-reported outcomes following living donor nephrectomy
Kidney transplantation is the optimal treatment for patients with end stage renal disease. In Norway almost 40 % of all renal transplants are performed with organs from living donors, and efforts are made to increase the number of kidneys available for transplantation. The purpose of this thesis was to study clinical and patient-reported outcomes following living kidney donor nephrectomy, with particular emphasis on patient-reported outcomes. A combination of quantitative and qualitative research approaches was used. In a randomized, controlled trial of 122 donors we compared laparoscopic and open donor nephrectomy, focusing on donor safety, postoperative pain, sick leave, health status and overall quality of life at 1, 6 and 12 months follow-up. To explore donor experiences of going through surgery 12 donors were in-depth interviewed at one week and at one year after open donor nephrectomy.
The results from the randomized trial demonstrated that the conventional open donor nephrectomy was superior to laparoscopic donor nephrectomy with regard to donor safety. Yet, an uncomplicated laparoscopic donor nephrectomy had important short-term advantages such as less analgesic requirements, less postoperative pain, shorter sick leave, and better health status and as compared to the open approach. Long-term follow up revealed significant differences in favour of laparoscopy only when adjusting for reoperations and convertions. We therefore conclude that long term benefits are hard to prove in favour of the laparoscopic technique. The in-depth interviews revealed that a positive feeling about being a donor was the dominant theme in both interview series. Though experiencing disincentives from surgery during the first postoperative period, the donors expressed that they were back to their normal health at one year after surgery. Donors experiencing unsuccessful recipient outcome did not regret donation.
Publications not indexed by PubMed:
Dueland, Svein; Line, Pål Dag; Hagness, Morten; Foss, Aksel; Andersen, Marit Helen.
Long‐term quality of life after liver transplantation for non‐resectable colorectal metastases confined to the liver.
JBJS Open Access 2018 s. -
Haraldstad, Kristin; Wahl, Astrid Klopstad; Andenæs, Randi; Andersen, John Roger; Andersen, Marit Helen; Elisabeth Grov, Beisland; Råheim Borge, Christine; Engebretsen, Eivind; Eisemann, Martin; Halvorsrud, Liv Torill; Hanssen, Tove Aminda; Haugstvedt, Anne; Haugland, Trude; Johansen, Venke A; Løvereide, Lise; Larsen, Marie Hamilton; Løyland, Borghild; Kvarme, Lisbeth Gravdal; Moons, Philip; Norekvål, Tone M.; Ribu, Lis; Urstad, Kristin Hjorthaug; Rohde, Gudrun Elin; Helseth, Sølvi.
A systematic snapshot review of quality of life research in medicine and health sciences.
Internasjonal livskvalitetskonferanse, ISOQOL; 2018-10-24 - 2018-10-28.
Engebretsen, Eivind; Andersen, Marit Helen; Urstad, Kristin Hjorthaug; Wahl, Astrid Klopstad.
Action Research in Implementation and Evaluation. Outline of a Study of a Training Programme for Kidney Transplant Recipients. I: Theory and Methodology in International Comparative Classroom Studies.
Cappelen Damm Akademisk 2014 ISBN 978–82-02–47061–6. s. 256-266.
Foss, Aksel; Andersen, Marit Helen; Hagness, Morten; Vidnes, Tone Karine; Finstad, Ellen Drolsum; Wahl, Astrid Klopstad; Dueland, Svein.
Patient Survival and Quality of Life Following Liver Transplantation for Colorectal Liver Metastases.
Liver transplantation 2010 ;Volum 16.(6) s. S189-S190.
Indexed by PubMed:
Evaluation of tools for annual capture of adherence to immunosuppressive medications after renal transplantation - a single-centre open prospective trial
Transpl Int (in press)
Intravenous Patient-controlled Analgesia Versus Thoracic Epidural Analgesia After Open Liver Surgery: A Prospective, Randomized, Controlled, Noninferiority Trial
Ann Surg (in press)
Psychosocial and clinical outcomes of percutaneous versus surgical pulmonary valve implantation
Open Heart, 5 (1), e000758
Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial
Ann Surg, 267 (2), 199-207
How does a new patient education programme for renal recipients become situated and adapted when implemented in the daily teaching practice in a university hospital? An ethnographic observation study
BMJ Open, 8 (11), e023005
Improved Health-Related Quality of Life in Older Kidney Recipients 1 Year After Transplantation
Transplant Direct, 4 (4), e351
Changes in health-related quality of life in older candidates waiting for kidney transplantation
Nephrology (Carlton), 23 (10), 948-956
Older kidney transplantation candidates' expectations of improvement in life and health following kidney transplantation: semistructured interviews with enlisted dialysis patients aged 65 years and older
BMJ Open, 8 (6), e021275
Implementation of a new patient education programme for renal transplant recipients
J Ren Care, 44 (2), 106-114
Lack of cross-cultural validity of the Endometriosis Health Profile-30
J Endometr Pelvic Pain Disord, 10 (2), 107-115
Health-related quality of life in women with endometriosis, compared with the general population and women with rheumatoid arthritis
Acta Obstet Gynecol Scand, 97 (11), 1339-1348
In-hospital cost comparison between percutaneous pulmonary valve implantation and surgery
Eur J Cardiothorac Surg, 51 (4), 747-753
Exploring nurse managers' perception of using the RAFAELA system as a management tool in a Norwegian hospital setting
Nurs Open, 5 (1), 77-83
Long-term experiences of Norwegian live kidney donors: qualitative in-depth interviews
BMJ Open, 7 (2), e014072
Relationships Between Clinical, Self-Reported, and Donation Specific Outcomes: A Prospective Follow-up Study 10 Years After Kidney Donation
Ann Transplant, 22, 148-155
Donation after circulatory death - an expanded opportunity for donation appreciated by families
J Crit Care, 43, 306-311
Nursing intensity and costs of nurse staffing demonstrated by the RAFAELA system: liver vs. kidney transplant recipients
J Nurs Manag, 24 (6), 798-805
Long-term, self-reported health outcomes in kidney donors
BMC Nephrol, 17, 8
Open versus laparoscopic liver resection for colorectal liver metastases (the Oslo-CoMet Study): study protocol for a randomized controlled trial
Trials, 16, 73
A qualitative study of manager experiences using the RAFAELA system
Open Journal of Nursing, 5, 1224-1232
Testing reliability and validity of the Oulu Patient Classification instrument- the first step in evaluating the RAFAELA system in Norway
OJN, 4, 303-311
Perceived health after percutaneous pulmonary valve implantation: in-depth interviews of patients and next-of-kin
BMJ Open, 4 (7), e005102
The RAFAELA system: a workforce planning tool for nurse staffing and human resource management
Nurs Manag (Harrow), 21 (2), 30-6
Quality of life following liver transplantation in patients with liver metastases from colorectal carcinoma
Scand J Caring Sci, 26 (4), 713-9
Renal recipients' educational experiences in the early post-operative phase--a qualitative study
Scand J Caring Sci, 26 (4), 635-42
Limited evidence for the effectiveness of educational interventions for renal transplant recipients. Results from a systematic review of controlled clinical trials
Patient Educ Couns, 90 (2), 147-54
The effect of an educational intervention for renal recipients: a randomized controlled trial
Clin Transplant, 26 (3), E246-53
Patient experiences following liver transplantation due to liver metastases from colorectal cancer
Eur J Oncol Nurs, 17 (3), 269-74
Qualitative study of pain of patients with chronic obstructive pulmonary disease
Heart Lung, 39 (3), 226-34
Patients' level of knowledge measured five days after kidney transplantation
Clin Transplant, 25 (4), 646-52
Cost effectiveness of open versus laparoscopic living-donor nephrectomy
Transplantation, 87 (6), 831-8
Changes in cardiac and cognitive function and self-reported outcomes at one year after coronary artery bypass grafting
J Thorac Cardiovasc Surg, 140 (1), 122-8
Follow-up interviews of 12 living kidney donors one yr after open donor nephrectomy
Clin Transplant, 21 (6), 702-9
Quality of life after randomization to laparoscopic versus open living donor nephrectomy: long-term follow-up
Transplantation, 84 (1), 64-9
Quality of life can both influence and be an outcome of general health perceptions after heart surgery
Health Qual Life Outcomes, 5, 27
Postoperative pain and convalescence in living kidney donors-laparoscopic versus open donor nephrectomy: a randomized study
Am J Transplant, 6 (6), 1438-43
Clinical and radiologic outcome of off-pump coronary surgery at 12 months follow-up: a prospective randomized trial
Ann Thorac Surg, 81 (6), 2089-95
Living donors' experiences 1 wk after donating a kidney
Clin Transplant, 19 (1), 90-6
Patient-reported outcome after randomization to on-pump versus off-pump coronary artery surgery
Ann Thorac Surg, 79 (5), 1584-9
Preoperative cerebral ischemic lesions predict physical health status after on-pump coronary artery bypass surgery
J Thorac Cardiovasc Surg, 130 (6), 1691-7
Laparoscopic versus open living-donor nephrectomy: experiences from a prospective, randomized, single-center study focusing on donor safety
Transplantation, 79 (9), 1236-40