Monocytes and microparticles in experimental and clinical settings of meningococcal disease – with special focus on tissue factor
Pro- and anti-inflammatory responses in human meningococcal disease.
Genetic changes in sepsis; Studies of gene expression in FFPE tissues from patients with systemic meningococcal disease
Laboratory-oriented coagulation research in patients with increased thrombotic or bleeding tendency
Identification and characterization of hemoglobinopathies in Norway
Association studies of DNA and RNA variation in health and disease
Endocytosis of extracellular vesicles (EV) in human monocytes
Implementation and validation of methods for isolation of EV from plasma
Functional microparticle (MP)-associated tissue factor (TF) as a potential biomarker of thrombosis in cancer
Characterization of extracellular vesicles from human skeletal muscle cells
Functional roles of plasma extracellular vesicles in cardiovascular disease.
Recent publications
Brusletto BS, Løberg EM, Hellerud BC, Goverud IL, Berg JP, Olstad OK, Gopinathan U, Brandtzaeg P, Øvstebø R(2020) Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis Front Cell Infect Microbiol, 10, 42 DOI 10.3389/fcimb.2020.00042, PubMed 32154187
Gautvik KM, Günther CC, Prijatelj V, Medina-Gomez C, Shevroja E, Rad LH, Yazdani M, Lindalen E, Valland H, Gautvik VT, Olstad OK, Holden M, Rivadeneira F, Utheim TP, Reppe S(2020) Distinct Subsets of Noncoding RNAs Are Strongly Associated With BMD and Fracture, Studied in Weight-Bearing and Non-Weight-Bearing Human Bone J Bone Miner Res DOI 10.1002/jbmr.3974, PubMed 32017184
Lunde LK, Skare Ø, Mamen A, Sirnes PA, Aass HCD, Øvstebø R, Goffeng E, Matre D, Nielsen P, Heglum HSA, Hammer SE, Skogstad M(2020) Cardiovascular Health Effects of Shift Work with Long Working Hours and Night Shifts: Study Protocol for a Three-Year Prospective Follow-Up Study on Industrial Workers Int J Environ Res Public Health, 17(2) DOI 10.3390/ijerph17020589, PubMed 31963313