Research projects

Extracellular vesicles

  • Characterization of extracellular vesicles from human plasma, human skeletal muscle cells, saliva and tear fluid from healthy and diseased donors.
  • Implementation and validation of methods for isolation of EV from plasma
  • Functional roles of plasma extracellular vesicles in cardiovascular disease

Laboratory-oriented coagulation research in patients with increased thrombotic or bleeding tendency

  • Hemostatic changes during pregnancy and postpartum – in women with and without increased tendency
  • Traumatic cascadopathy: A study of inflammation and coagulation after severe trauma using high-resolution data capture
  • Molecular and functional characterization of defects in patients with increased bleeding and thrombotic tendency
  • Thrombin generation and complement activation over time in patients with antiphospholipid syndrome
  • Evaluation of the ability of recombinant coagulation factor VIIa to generate factor Xa, thrombin, fibrin and the binding to platelets

Identification and characterization of hemoglobinopathies in Norway

  • Influence on erythrocyte variables

Inflammation and coagulation in human meningococcal disease.

  • mRNA and non-coding RNA in FFPE tissue
 
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