Olav Klingenberg

  • Senior consultant; MD, PhD
  • +47 22 11 94 68

Original articles

Fjeld B, Sudmann-Day ÅA, Grimholt RM, Klingenberg O (2019)
Might the patient have thalassaemia or a haemoglobin variant?
Tidsskr Nor Laegeforen, 139 (17)
DOI 10.4045/tidsskr.19.0121, PubMed 31746162

Grimholt RM, Fjeld B, Selsås H, Schwettmann L, Klingenberg O (2019)
Hb Aalesund (HBA2: c.400_406delAGCACCG), an Unstable α-Globin Variant Found in a Norwegian Patient Causing Moderate Hemolytic Anemia and Falsely High Hb A1c Using Ion Exchange High Performance Liquid Chromatography
Hemoglobin, 43 (2), 122-125
DOI 10.1080/03630269.2019.1614048, PubMed 31145010

Grimholt RM, Vestli A, Urdal P, Bechensteen AG, Fjeld B, Dalhus B, Klingenberg O (2018)
Hb Oslo [β42(CD1)Phe→Ile; HBB: c.127T>A]: A Novel Unstable Hemoglobin Variant Found in a Norwegian Patient
Hemoglobin, 42 (2), 78-83
DOI 10.1080/03630269.2018.1468773, PubMed 30032685

Grimholt RM, Harteveld CL, Arkesteijn SGJ, Fjeld B, Klingenberg O (2018)
Characterization of Two Deep Intronic Variants on the β-Globin Gene with Inconsistent Interpretations of Clinical Significance
Hemoglobin, 42 (2), 126-128
DOI 10.1080/03630269.2018.1473255, PubMed 30047296

Sagedal S, Sandvik L, Klingenberg O, Sandset PM (2017)
β-Thromboglobulin may not reflect platelet activation during haemodialysis with the HeprAN membrane
Scand J Clin Lab Invest, 77 (8), 679-684
DOI 10.1080/00365513.2017.1397288, PubMed 29117741

Klingenberg O, Furuset T, Hestbråten CR, Hallberg MH, Steiro A, Orset IR, Berg JP (2017)
HbA1c analysis by capillary electrophoresis - comparison with chromatography and an immunological method
Scand J Clin Lab Invest, 77 (6), 458-464
DOI 10.1080/00365513.2017.1338747, PubMed 28644050

Lindberg A, Holm AM, Hilberg O, Harju T, Vestbo J, Foronjy R, Harju T, Nurmos NI, Karvonen H, Lappi-Blanco E, Skold M, Lehtonen S, Kaarteenaho R, Backman H, Christensen VL, Rustoen T, Cooper BA, Miaskowski C, Henriksen AH, Bentsen SB, Holm AM, Andersson M, Waatevik M, Johannessen A, Real FG et al. (2017)
VII Scandinavian Copd Research Symposium, Holmenkollen, Oslo 18th-19th November 2016
EUR. CLIN. RESPIR. J., 5 1, 1401867

Berntsen NL, Klingenberg O, Juran BD, Benito de Valle M, Lindkvist B, Lazaridis KN, Boberg KM, Karlsen TH, Hov JR (2015)
Association Between HLA Haplotypes and Increased Serum Levels of IgG4 in Patients With Primary Sclerosing Cholangitis
Gastroenterology, 148 (5), 924-927.e2
DOI 10.1053/j.gastro.2015.01.041, PubMed 25655558

Sudmann-Day ÅA, Piehler A, Klingenberg O, Urdal P (2015)
Six-day stability of erythrocyte and reticulocyte parameters in-vitro: a comparison of blood samples from healthy, iron-deficient, and thalassemic individuals
Scand J Clin Lab Invest, 75 (3), 247-53
DOI 10.3109/00365513.2014.1000370, PubMed 25608597

Urdal P, Amundsen EK, Toska K, Klingenberg O (2014)
Automated alarm to detect antigen excess in serum free immunoglobulin light chain kappa and lambda assays
Scand J Clin Lab Invest, 74 (7), 575-81
DOI 10.3109/00365513.2014.915426, PubMed 25007050

Grimholt RM, Urdal P, Klingenberg O, Piehler AP (2014)
Rapid and reliable detection of α-globin copy number variations by quantitative real-time PCR
BMC Hematol, 14 (1), 4
DOI 10.1186/2052-1839-14-4, PubMed 24456650

Grimholt RM, Sudmann ÅA, Piehler AP, Urdal P, Klingenberg O (2013)
Hb Ullevaal [β78(EF2)Leu→Val; HBB: c.235C>G], a new hemoglobin variant interfering with Hb A1c measurement using a cation exchange high performance liquid chromatography method
Hemoglobin, 38 (2), 130-2
DOI 10.3109/03630269.2013.858640, PubMed 24274186

Henriksson CE, Hellum M, Haug KB, Aass HC, Joø GB, Øvstebø R, Trøseid AM, Klingenberg O, Kierulf P (2011)
Anticoagulant effects of an antidiabetic drug on monocytes in vitro
Thromb Res, 128 (5), e100-6
DOI 10.1016/j.thromres.2011.07.007, PubMed 21862110

Bachmann-Harildstad G, Stenklev NC, Myrvoll E, Jablonski G, Klingenberg O (2011)
β-trace protein as a diagnostic marker for perilymphatic fluid fistula: a prospective controlled pilot study to test a sample collection technique
Otol Neurotol, 32 (1), 7-10
DOI 10.1097/mao.0b013e3181fc74d0, PubMed 21192373

Sagedal S, Witczak BJ, Osnes K, Hartmann A, Os I, Eikvar L, Klingenberg O, Brosstad F (2011)
A heparin-coated dialysis filter (AN69 ST) does not reduce clotting during hemodialysis when compared to a conventional polysulfone filter (F×8)
Blood Purif, 32 (3), 151-5
DOI 10.1159/000325227, PubMed 21659742

Jensen T, Kierulf P, Sandset PM, Klingenberg O, Joø GB, Godal HC, Skjønsberg OH (2007)
Fibrinogen and fibrin induce synthesis of proinflammatory cytokines from isolated peripheral blood mononuclear cells
Thromb Haemost, 97 (5), 822-9
DOI 10.1160/th07-01-0039, PubMed 17479194

Knudsen GP, Pedersen J, Klingenberg O, Lygren I, Ørstavik KH (2007)
Increased skewing of X chromosome inactivation with age in both blood and buccal cells
Cytogenet Genome Res, 116 (1-2), 24-8
DOI 10.1159/000097414, PubMed 17268174

Henriksson CE, Klingenberg O, Hellum M, Landsverk KS, Joø GB, Westvik AB, Kierulf P (2006)
Calcium ionophore-induced de-encryption of tissue factor in monocytes is associated with extensive cell death
Thromb Res, 119 (5), 621-30
DOI 10.1016/j.thromres.2006.05.012, PubMed 16844202

Henriksson CE, Hellum M, Landsverk KS, Klingenberg O, Joø GB, Kierulf P (2006)
Flow cytometry-sorted non-viable endotoxin-treated human monocytes are strongly procoagulant
Thromb Haemost, 96 (1), 29-37
DOI 10.1160/TH06-01-0052, PubMed 16807648

Henriksson CE, Klingenberg O, Ovstebø R, Joø GB, Westvik AB, Kierulf P (2005)
Discrepancy between tissue factor activity and tissue factor expression in endotoxin-induced monocytes is associated with apoptosis and necrosis
Thromb Haemost, 94 (6), 1236-44
DOI 10.1160/TH05-07-0463, PubMed 16411400

Citores L, Khnykin D, Sørensen V, Wesche J, Klingenberg O, Wiedłocha A, Olsnes S (2001)
Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain
J Cell Sci, 114 (Pt 9), 1677-89
PubMed 11398757

Klingenberg O, Wiedlocha A, Rapak A, Khnykin D, Citores L, Olsnes S (2000)
Requirement for C-terminal end of fibroblast growth factor receptor 4 in translocation of acidic fibroblast growth factor to cytosol and nucleus
J Cell Sci, 113 ( Pt 10), 1827-38
PubMed 10769213

Klingenberg O, Wiedlocha A, Olsnes S (1999)
Effects of mutations of a phosphorylation site in an exposed loop in acidic fibroblast growth factor
J Biol Chem, 274 (25), 18081-6
DOI 10.1074/jbc.274.25.18081, PubMed 10364261

Kolpakova E, Wiedłocha A, Stenmark H, Klingenberg O, Falnes PO, Olsnes S (1998)
Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor
Biochem J, 336 ( Pt 1), 213-22
DOI 10.1042/bj3360213, PubMed 9806903

Klingenberg O, Widlocha A, Rapak A, Muñoz R, Falnes P, Olsnes S (1998)
Inability of the acidic fibroblast growth factor mutant K132E to stimulate DNA synthesis after translocation into cells
J Biol Chem, 273 (18), 11164-72
DOI 10.1074/jbc.273.18.11164, PubMed 9556604

Muñoz R, Klingenberg O, Wiedłocha A, Rapak A, Falnes PO, Olsnes S (1997)
Effect of mutation of cytoplasmic receptor domain and of genistein on transport of acidic fibroblast growth factor into cells
Oncogene, 15 (5), 525-36
DOI 10.1038/sj.onc.1201226, PubMed 9247306

Klingenberg O, Olsnes S (1996)
Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin
Biochem J, 313 ( Pt 2), 647-53
DOI 10.1042/bj3130647, PubMed 8573105

Wiedłocha A, Falnes PO, Rapak A, Muñoz R, Klingenberg O, Olsnes S (1996)
Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization
Mol Cell Biol, 16 (1), 270-80
DOI 10.1128/mcb.16.1.270, PubMed 8524304

Wiedłocha A, Falnes PO, Rapak A, Klingenberg O, Muñoz R, Olsnes S (1995)
Translocation of cytosol of exogenous, CAAX-tagged acidic fibroblast growth factor
J Biol Chem, 270 (51), 30680-5
DOI 10.1074/jbc.270.51.30680, PubMed 8530506

Review articles

Olsnes S, Klingenberg O, Wiedłocha A (2003)
Transport of exogenous growth factors and cytokines to the cytosol and to the nucleus
Physiol Rev, 83 (1), 163-82
DOI 10.1152/physrev.00021.2002, PubMed 12506129

Klingenberg O, Wiedocha A, Citores L, Olsnes S (2000)
Requirement of phosphatidylinositol 3-kinase activity for translocation of exogenous aFGF to the cytosol and nucleus
J Biol Chem, 275 (16), 11972-80
DOI 10.1074/jbc.275.16.11972, PubMed 10766827

Other articles

Fjeld B, Sudmann-Day AA, Grimholt RM, Klingenberg O (2019)
Can the patient have thalassemia or a hemoglobin variant?
Tidsskr. Nor. Laegeforen., 139 (17), 1679

Grimholt RM, Urdal P, Klingenberg O, Piehler AP (2019)
Correction to: Rapid and reliable detection of α-globin copy number variations by quantitative real-time PCR
BMC Hematol, 19, 13
DOI 10.1186/s12878-019-0144-5, PubMed 31695920

Klingenberg O (2017)
Hemoglobin amino acids by the numbers
Scand J Clin Lab Invest, 77 (1), 1
DOI 10.1080/00365513.2017.1267428, PubMed 27937007

Hausken J, Klingenberg O, Mørkrid L, Rollag H, Foss A, Midtvedt K (2012)
Elevated troponin I and NT-proBNP at the time of transplantation may predict a major adverse cardiac event in the early postoperative period after renal transplantation
Transplantation, 94 (2), e15-6
DOI 10.1097/TP.0b013e31825b7633, PubMed 22820562


Klingenberg O (1999)
Translocation of acidic fibroblast growth factor from thecell surface to the cytosol and nucleus
Department of Biochemistry, Institute for Cancer Research, Norwegian Radium Hospital and Norwegian Cancer Society, [Oslo], 1 b. (flere pag.)
BIBSYS 990881717, ISBN 82-7633-124-6

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