Light Meets Precision:
EIC Pathfinder Project SCALPEL Pioneering a Revolutionary Photoimmunotherapy for Cancer
Theo Theodossiou, Project coordinator
In a groundbreaking effort to revolutionise modern oncology, the SCALPEL project launches a Europe wide initiative aimed at redefining cancer treatment by using light to precisely ‘click’ tags to cancer cells, enabling the immune system to recognise and destroy them with unparalleled accuracy. Project coordinator is Theo Theodossiou, head of the Protonics project group at the Department of Radiation Biology at OUH.
The multidisciplinary initiative funded by the European Innovation Council Pathfinder programme under Horizon Europe with a total budget of more than EUR 4 million aims to revolutionise modern oncology offering new hope for millions worldwide.
Published in Level 2 journals, first or last author from Oslo University Hospital.
Distler O, Antonopoulou K, Galetti I, Wheatley MJ, Aggarwal R, Allanore Y, Emery P, Kaneko Y, Kreuter M, Bery-Janusko F, Moros L, Hoffmann-Vold AM(2026) Patient reports of evaluations for interstitial lung disease in patients with connective tissue diseases and rheumatoid arthritis: an international survey Respir Res(in press) DOI 10.1186/s12931-026-03795-z, PubMed 42436526
Hindley G, Mizuno Y, Beck K, Carreira Figueiredo I, Pillinger T, Jeljeli S, Dunn J, Hammers A, Awais R, Sander K, Årstad E, Lythgoe DJ, Schubert JJ, Veronese M, Turkheimer F, Howes OD, Reis Marques T(2026) Does a monoclonal antibody targeting immune cells affect glutamatergic level in schizophrenia? A multimodal PET/MRS brain imaging study Neuropsychopharmacology(in press) DOI 10.1038/s41386-026-02466-3, PubMed 42426247
Grün W, Poulsen M, Riiser MØ, Hvaal K, Husebye EE, Stødle AH(2026) A Randomized Controlled Trial of Primary Arthrodesis Versus Temporary Bridge Plating in Unstable Lisfranc Injuries: A Concise Follow-up, at 10 Years, of a Previous Report J Bone Joint Surg Am(in press) DOI 10.2106/JBJS.26.00020, PubMed 42424434