Therapeutic Drug Monitoring and Clincial Toxicology

Publications 2024

Halvorsen LV, Søraas CL, Larstorp ACK, Hjørnholm U, Kjær VN, Liestøl K, Aune A, Olsen E, Brobak KM, Bergland OU, Rognstad S, Aarskog NR, Heimark S, Fadl Elmula FEM, Gerdts E, Mo R, Solbu MD, Opdal MS, Kjeldsen SE, Rostrup M, Høieggen A (2024)
Effect of Therapeutic Drug Monitoring on Adherence and Blood Pressure: A Multicenter Randomized Clinical Trial
Am J Hypertens, 37 (10), 826-836
DOI 10.1093/ajh/hpae059, PubMed 38713475

Havig SM, Berg-Pedersen RM, Krabseth HM, Müller LD, Haugaa K, Zare HK, Gjesdal K, Krajci P, Opdal MS (2024)
Effect on QTc interval by switching from methadone to equipotent R-methadone dose in methadone maintenance treatment patients
Basic Clin Pharmacol Toxicol, 134 (4), 519-530
DOI 10.1111/bcpt.13982, PubMed 38308508

Opdal MS, Rognstad S, Edvardsen F, Halvorsen LV, Mo R, Gustavsen I, Larstorp ACK, Søraas CL, Helland A (2024)
[Not Available]
Tidsskr Nor Laegeforen, 144
DOI 10.4045/tidsskr.24.0407, PubMed 39149754

Opdal MS, Rognstad S, Edvardsen F, Halvorsen LV, Mo R, Gustavsen I, Larstorp ACK, Søraas CL, Helland A (2024)
Usefulness of measuring the serum concentration of antihypertensive drugs in uncontrolled hypertension
Tidsskr Nor Laegeforen, 144 (9)
DOI 10.4045/tidsskr.24.0167, PubMed 39167005

Publications 2022

Halvorsen LV, Bergland OU, Søraas CL, Larstorp ACK, Hjørnholm U, Kjær VN, Kringen MK, Clasen PE, Haldsrud R, Kjeldsen SE, Rostrup M, Fadl Elmula FEM, Opdal MS, Høieggen A (2022)
Nonadherence by Serum Drug Analyses in Resistant Hypertension: 7-Year Follow-Up of Patients Considered Adherent by Directly Observed Therapy
J Am Heart Assoc, 11 (18), e025879
DOI 10.1161/JAHA.121.025879, PubMed 36073648

Thorstensen CW, Clasen PE, Rognstad S, Haldsrud R, Føreid S, Helstrøm T, Bergland OU, Halvorsen LV, Aune A, Olsen E, Brobak KM, Høieggen A, Gustavsen I, Larstorp ACK, Søraas CL, Opdal MS (2022)
Development of UHPLC-MS/MS methods to quantify 25 antihypertensive drugs in serum in a cohort of patients treated for hypertension
J Pharm Biomed Anal, 219, 114908
DOI 10.1016/j.jpba.2022.114908, PubMed 35803015

Publications 2021

Bergland OU, Halvorsen LV, Søraas CL, Hjørnholm U, Kjær VN, Rognstad S, Brobak KM, Aune A, Olsen E, Fauchald YM, Heimark S, Thorstensen CW, Liestøl K, Solbu MD, Gerdts E, Mo R, Rostrup M, Kjeldsen SE, Høieggen A, Opdal MS, Larstorp ACK, Fadl Elmula FEM (2021)
Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations
Hypertension, 78 (3), 617-628
DOI 10.1161/HYPERTENSIONAHA.121.17514, PubMed 34275336

Rognstad S, Søraas CL, Bergland OU, Høieggen A, Strømmen M, Helland A, Opdal MS (2021)
Establishing Serum Reference Ranges for Antihypertensive Drugs
Ther Drug Monit, 43 (1), 116-125
DOI 10.1097/FTD.0000000000000806, PubMed 32881780

Publications 2019

Larsen Burns M, Kinge E, Stokke Opdal M, Johannessen SI, Johannessen Landmark C (2019)
Therapeutic drug monitoring of gabapentin in various indications
Acta Neurol Scand, 139 (5), 446-454
DOI 10.1111/ane.13075, PubMed 30710348

Publications 2018

Müller LD, Opdal MS (2018)
Developing a rapid semi-automated sample preparation with alkaline hydrolysis in a 96-well plate for quantification of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in urine samples by UHPLC-MS/MS
J Pharm Biomed Anal, 161, 296-304
DOI 10.1016/j.jpba.2018.08.045, PubMed 30189411

Publications 2016

Burns ML, Baftiu A, Opdal MS, Johannessen SI, Landmark CJ (2016)
Therapeutic Drug Monitoring of Clobazam and Its Metabolite-Impact of Age and Comedication on Pharmacokinetic Variability
Ther Drug Monit, 38 (3), 350-7
DOI 10.1097/FTD.0000000000000272, PubMed 26751267

Haga C, Opdal MS, Tuv SS, Zahl PH, Stenberg-Nilsen H (2016)
[Drug safety associated with the change of digitalis drug in Norway]
Tidsskr Nor Laegeforen, 136 (20), 1714-1718
DOI 10.4045/tidsskr.15.0161, PubMed 27830905

Opdal MS, Johansen PW (2016)
Useful and necessary about new anticoagulants
Tidsskr Nor Laegeforen, 136 (18), 1505
DOI 10.4045/tidsskr.16.0786, PubMed 27731583

Publications 2015

Opdal MS, Arnesen M, Müller LD, Hullstein I, Sayed K, Brørs O, Kringen M, Sagedal S, Gjesdal K, Krajci P (2015)
Effects of Hemodialysis on Methadone Pharmacokinetics and QTc
Clin Ther, 37 (7), 1594-9
DOI 10.1016/j.clinthera.2015.04.009, PubMed 25963997

Publications 2014

Kringen MK, Piehler AP, Grimholt RM, Opdal MS, Haug KB, Urdal P (2014)
Serum bilirubin concentration in healthy adult North-Europeans is strictly controlled by the UGT1A1 TA-repeat variants
PLoS One, 9 (2), e90248
DOI 10.1371/journal.pone.0090248, PubMed 24587300

Publications 2012

Opdal MS (2012)
[Sick from sickness, substance abuse or medicine]
Tidsskr Nor Laegeforen, 132 (1), 52
DOI 10.4045/tidsskr.11.0906, PubMed 22240832

Publications 2010

Al-Samarraie MS, Karinen R, Mørland J, Stokke Opdal M (2010)
Blood GHB concentrations and results of medical examinations in 25 car drivers in Norway
Eur J Clin Pharmacol, 66 (10), 987-98
DOI 10.1007/s00228-010-0870-x, PubMed 20717656

Kringen MK, Haug KB, Grimholt RM, Stormo C, Narum S, Opdal MS, Fosen JT, Piehler AP, Johansen PW, Seljeflot I, Berg JP, Brørs O (2010)
Genetic variation of VKORC1 and CYP4F2 genes related to warfarin maintenance dose in patients with myocardial infarction
J Biomed Biotechnol, 2011, 739751
DOI 10.1155/2011/739751, PubMed 21127708

Publications 2009

Al-Samarraie MS, Karinen R, Rognum T, Hasvold I, Opdal Stokke M, Christophersen AS (2009)
Lethal poisoning with ethiofencarb and ethanol
J Anal Toxicol, 33 (7), 389-92
DOI 10.1093/jat/33.7.389, PubMed 19796510

Oiestad EL, Johansen U, Stokke Opdal M, Bergan S, Christophersen AS (2009)
Determination of digoxin and digitoxin in whole blood
J Anal Toxicol, 33 (7), 372-8
DOI 10.1093/jat/33.7.372, PubMed 19796507

Publications 2008

Khiabani HZ, Opdal MS, Mørland J (2008)
Blood alcohol concentrations in apprehended drivers of cars and boats suspected to be impaired by the police
Traffic Inj Prev, 9 (1), 31-6
DOI 10.1080/15389580701737629, PubMed 18338292

Publications 2007

Al-Samarraie M, Khiabani HZ, Opdal MS (2007)
[Khat--a new drug of abuse in Norway]
Tidsskr Nor Laegeforen, 127 (5), 574-6
PubMed 17332809

Bernard JP, Opdal MS, Karinen R, Mørland J, Khiabani HZ (2007)
Relationship between methadone and EDDP (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) in urine samples from Norwegian prisons
Eur J Clin Pharmacol, 63 (8), 777-82
DOI 10.1007/s00228-007-0314-4, PubMed 17576548

Publications 2006

Bernard JP, Opdal MS, Khiabani H (2006)
[General pharmacodynamic principles]
Tidsskr Nor Laegeforen, 126 (16), 2107-9
PubMed 16932780

Kristoffersen L, Øiestad EL, Opdal MS, Krogh M, Lundanes E, Christophersen AS (2006)
Simultaneous determination of 6 beta-blockers, 3 calcium-channel antagonists, 4 angiotensin-II antagonists and 1 antiarrhythmic drug in post-mortem whole blood by automated solid phase extraction and liquid chromatography mass spectrometry. Method development and robustness testing by experimental design
J Chromatogr B Analyt Technol Biomed Life Sci, 850 (1-2), 147-60
DOI 10.1016/j.jchromb.2006.11.030, PubMed 17175206

Publications 2004

Opdal MS (2004)
[Clinical pharmacology education and internship]
Tidsskr Nor Laegeforen, 124 (13-14), 1828-9
PubMed 15229693