Per Kristian Eide

  • Professor MD, PhD
  • +47 23074321

Head of NHRG

Per Kristian Eide received his MD from Faculty of Medicine, University of Bergen in 1989, and the same year his PhD in Neurophysiology from the Department of Physiology, Faculty of Medicine, University of Bergen, Bergen, Norway. He is a professor of clinical neurosurgery, Faculty of Medicine, University of Oslo, and senior consultant neurosurgeon/section chief (hydrocephalus) at the Department of Neurosurgery, Oslo University Hospital – Rikshospitalet. Eide’s current research involves several areas: (1) Pathophysiology of hydrocephalus and other diseases with imbalance in brain water homeostasis (idiopathic intracranial hypertension, cysts, Chiari malformation etc.) (2) Physiological monitoring of patients with brain disease/injury regarding (intracranial pressure, arterial blood pressure, intracranial compliance, cerebral auto-regulation, and non-invasive ICP monitoring). (3) Monitoring and treatment of patients with subarachnoid hemorrhage. His current main clinical activities are shunt/endoscopic surgery for hydrocephalus and other cerebrospinal fluid (CSF ) circulation disorders (idiopathic intracranial hypertension, normal pressure hydrocephalus, Chiari malformation), cerebrovascular surgery (cerebral aneurysms, cerebal vascular malformations), microvascular decompressions (trigeminal neuralgia, hemifacial spasms, glossopharyngeal neuralgia, vertigo), and surgery for brain tumors (posterior skull base, ventricular).

Thesis: Function and plasticity of serotonergic systems in the regulation of nociception

 

Author network for Per Kristian Eide by COREMINE medical


Publications 2018

Eide PK, Ringstad G (2018)
Delayed clearance of cerebrospinal fluid tracer from entorhinal cortex in idiopathic normal pressure hydrocephalus: A glymphatic magnetic resonance imaging study
J Cereb Blood Flow Metab, 271678X18760974 (in press)
DOI 10.1177/0271678X18760974, PubMed 29485341

Eide PK, Sorteberg A, Sorteberg W, Lindstrøm EK, Mardal KA, Ringstad G (2018)
"Bucket" cerebrospinal fluid bulk flow: when the terrain disagrees with the map
Acta Neurochir (Wien) (in press)
DOI 10.1007/s00701-018-3775-6, PubMed 30560378

Eide PK, Vatnehol SAS, Emblem KE, Ringstad G (2018)
Magnetic resonance imaging provides evidence of glymphatic drainage from human brain to cervical lymph nodes
Sci Rep, 8 (1), 7194
DOI 10.1038/s41598-018-25666-4, PubMed 29740121

Eidsvaag VA, Hansson HA, Heuser K, Nagelhus EA, Eide PK (2018)
Cerebral microvascular abnormalities in patients with idiopathic intracranial hypertension
Brain Res, 1686, 72-82
DOI 10.1016/j.brainres.2018.02.017, PubMed 29477544

Evensen KB, Eide PK (2018)
Noninvasive Estimation of Intracranial Pressure Waveform from Central Aortic Pressure Waveform
World Neurosurg, 121, 257-258
DOI 10.1016/j.wneu.2018.10.079, PubMed 30347297

Evensen KB, O'Rourke M, Prieur F, Holm S, Eide PK (2018)
Non-invasive Estimation of the Intracranial Pressure Waveform from the Central Arterial Blood Pressure Waveform in Idiopathic Normal Pressure Hydrocephalus Patients
Sci Rep, 8 (1), 4714
DOI 10.1038/s41598-018-23142-7, PubMed 29549286

Evensen KB, Paulat K, Prieur F, Holm S, Eide PK (2018)
Utility of the Tympanic Membrane Pressure Waveform for Non-invasive Estimation of The Intracranial Pressure Waveform
Sci Rep, 8 (1), 15776
DOI 10.1038/s41598-018-34083-6, PubMed 30361489

Hasan-Olive MM, Enger R, Hansson HA, Nagelhus EA, Eide PK (2018)
Loss of perivascular aquaporin-4 in idiopathic normal pressure hydrocephalus
Glia, 67 (1), 91-100
DOI 10.1002/glia.23528, PubMed 30306658

Korhonen VE, Helisalmi S, Jokinen A, Jokinen I, Lehtola JM, Oinas M, Lönnrot K, Avellan C, Kotkansalo A, Frantzen J, Rinne J, Ronkainen A, Kauppinen M, Junkkari A, Hiltunen M, Soininen H, Kurki M, Jääskeläinen JE, Koivisto AM, Sato H, Kato T, Remes AM, Eide PK, Leinonen V (2018)
Copy number loss in SFMBT1 is common among Finnish and Norwegian patients with iNPH
Neurol Genet, 4 (6), e291
DOI 10.1212/NXG.0000000000000291, PubMed 30584596

Lindstrøm EK, Ringstad G, Mardal KA, Eide PK (2018)
Cerebrospinal fluid volumetric net flow rate and direction in idiopathic normal pressure hydrocephalus
Neuroimage Clin, 20, 731-741
DOI 10.1016/j.nicl.2018.09.006, PubMed 30238917

Lindstrøm EK, Ringstad G, Sorteberg A, Sorteberg W, Mardal KA, Eide PK (2018)
Magnitude and direction of aqueductal cerebrospinal fluid flow: large variations in patients with intracranial aneurysms with or without a previous subarachnoid hemorrhage
Acta Neurochir (Wien) (in press)
DOI 10.1007/s00701-018-3730-6, PubMed 30443816

Lindstrøm EK, Schreiner J, Ringstad GA, Haughton V, Eide PK, Mardal KA (2018)
Comparison of phase-contrast MR and flow simulations for the study of CSF dynamics in the cervical spine
Neuroradiol J, 31 (3), 292-298
DOI 10.1177/1971400918759812, PubMed 29464985

Ringstad G, Valnes LM, Dale AM, Pripp AH, Vatnehol SS, Emblem KE, Mardal KA, Eide PK (2018)
Brain-wide glymphatic enhancement and clearance in humans assessed with MRI
JCI Insight, 3 (13), e121537
DOI 10.1172/jci.insight.121537, PubMed 29997300

Publications 2017

Brix MK, Westman E, Simmons A, Ringstad GA, Eide PK, Wagner-Larsen K, Page CM, Vitelli V, Beyer MK (2017)
The Evans' Index revisited: New cut-off levels for use in radiological assessment of ventricular enlargement in the elderly
Eur J Radiol, 95, 28-32
DOI 10.1016/j.ejrad.2017.07.013, PubMed 28987681

Eide PK (2017)
The pathophysiology of chronic noncommunicating hydrocephalus: lessons from continuous intracranial pressure monitoring and ventricular infusion testing
J Neurosurg, 129 (1), 220-233
DOI 10.3171/2017.1.JNS162813, PubMed 28799879

Eide PK, Hansson HA (2017)
Astrogliosis and impaired aquaporin-4 and dystrophin systems in idiopathic normal pressure hydrocephalus
Neuropathol Appl Neurobiol, 44 (5), 474-490
DOI 10.1111/nan.12420, PubMed 28627088

Eidsvaag VA, Enger R, Hansson HA, Eide PK, Nagelhus EA (2017)
Human and mouse cortical astrocytes differ in aquaporin-4 polarization toward microvessels
Glia, 65 (6), 964-973
DOI 10.1002/glia.23138, PubMed 28317216

Eidsvaag VA, Hansson HA, Heuser K, Nagelhus EA, Eide PK (2017)
Brain Capillary Ultrastructure in Idiopathic Normal Pressure Hydrocephalus: Relationship With Static and Pulsatile Intracranial Pressure
J Neuropathol Exp Neurol, 76 (12), 1034-1045
DOI 10.1093/jnen/nlx091, PubMed 29040647

Frič R, Pripp AH, Eide PK (2017)
Cardiovascular risk factors in Chiari malformation and idiopathic intracranial hypertension
Brain Behav, 7 (5), e00677
DOI 10.1002/brb3.677, PubMed 28523220

Jain K, Ringstad G, Eide PK, Mardal KA (2017)
Direct numerical simulation of transitional hydrodynamics of the cerebrospinal fluid in Chiari I malformation: The role of cranio-vertebral junction
Int J Numer Method Biomed Eng, 33 (9)
DOI 10.1002/cnm.2853, PubMed 27863152

Meling TR, Romundstad L, Niemi G, Narum J, Eide PK, Sorteberg AG, Sorteberg WA (2017)
Adenosine-assisted clipping of intracranial aneurysms
Neurosurg Rev, 41 (2), 585-592
DOI 10.1007/s10143-017-0896-y, PubMed 28819885

Ringstad G, Lindstrøm EK, Vatnehol SAS, Mardal KA, Emblem KE, Eide PK (2017)
Non-invasive assessment of pulsatile intracranial pressure with phase-contrast magnetic resonance imaging
PLoS One, 12 (11), e0188896
DOI 10.1371/journal.pone.0188896, PubMed 29190788

Ringstad G, Vatnehol SAS, Eide PK (2017)
Glymphatic MRI in idiopathic normal pressure hydrocephalus
Brain, 140 (10), 2691-2705
DOI 10.1093/brain/awx191, PubMed 28969373

Publications 2016

Eide PK (2016)
The correlation between pulsatile intracranial pressure and indices of intracranial pressure-volume reserve capacity: results from ventricular infusion testing
J Neurosurg, 125 (6), 1493-1503
DOI 10.3171/2015.11.JNS151529, PubMed 26918478

Eide PK, Eidsvaag VA, Nagelhus EA, Hansson HA (2016)
Cortical astrogliosis and increased perivascular aquaporin-4 in idiopathic intracranial hypertension
Brain Res, 1644, 161-75
DOI 10.1016/j.brainres.2016.05.024, PubMed 27188961

Eide PK, Pripp AH (2016)
The prevalence of cardiovascular disease in non-communicating hydrocephalus
Clin Neurol Neurosurg, 149, 33-8
DOI 10.1016/j.clineuro.2016.07.024, PubMed 27455422

Eide PK, Pripp AH, Ringstad GA (2016)
Magnetic resonance imaging biomarkers indicate a central venous hypertension syndrome in patients with symptomatic pineal cysts
J Neurol Sci, 363, 207-16
DOI 10.1016/j.jns.2016.02.038, PubMed 27000252

Eide PK, Ringstad G (2016)
Increased pulsatile intracranial pressure in patients with symptomatic pineal cysts and magnetic resonance imaging biomarkers indicative of central venous hypertension
J Neurol Sci, 367, 247-55
DOI 10.1016/j.jns.2016.06.028, PubMed 27423599

Eide PK, Ringstad G (2016)
Results of surgery in symptomatic non-hydrocephalic pineal cysts: role of magnetic resonance imaging biomarkers indicative of central venous hypertension
Acta Neurochir (Wien), 159 (2), 349-361
DOI 10.1007/s00701-016-3029-4, PubMed 27878615

Frič R, Eide PK (2016)
Comparative observational study on the clinical presentation, intracranial volume measurements, and intracranial pressure scores in patients with either Chiari malformation Type I or idiopathic intracranial hypertension
J Neurosurg, 126 (4), 1312-1322
DOI 10.3171/2016.4.JNS152862, PubMed 27341045

Frič R, Lindstrøm EK, Ringstad GA, Mardal KA, Eide PK (2016)
The association between the pulse pressure gradient at the cranio-cervical junction derived from phase-contrast magnetic resonance imaging and invasively measured pulsatile intracranial pressure in symptomatic patients with Chiari malformation type 1
Acta Neurochir (Wien), 158 (12), 2295-2304
DOI 10.1007/s00701-016-2979-x, PubMed 27743249

Kim MO, Eide PK, O'Rourke MF, Adji A, Avolio AP (2016)
Intracranial Pressure Waveforms are More Closely Related to Central Aortic than Radial Pressure Waveforms: Implications for Pathophysiology and Therapy
Acta Neurochir Suppl, 122, 61-4
DOI 10.1007/978-3-319-22533-3_12, PubMed 27165878

Levinsky A, Papyan S, Weinberg G, Stadheim T, Eide PK (2016)
Non-invasive estimation of static and pulsatile intracranial pressure from transcranial acoustic signals
Med Eng Phys, 38 (5), 477-84
DOI 10.1016/j.medengphy.2016.02.009, PubMed 26997563

Støverud KH, Langtangen HP, Ringstad GA, Eide PK, Mardal KA (2016)
Computational Investigation of Cerebrospinal Fluid Dynamics in the Posterior Cranial Fossa and Cervical Subarachnoid Space in Patients with Chiari I Malformation
PLoS One, 11 (10), e0162938
DOI 10.1371/journal.pone.0162938, PubMed 27727298

Publications 2015

Eide PK, Lundar T (2015)
Arne Torkildsen and the ventriculocisternal shunt: the first clinically successful shunt for hydrocephalus
J Neurosurg, 124 (5), 1421-8
DOI 10.3171/2015.1.JNS142659, PubMed 26339852

Eide PK, Ringstad G (2015)
MRI with intrathecal MRI gadolinium contrast medium administration: a possible method to assess glymphatic function in human brain
Acta Radiol Open, 4 (11), 2058460115609635
DOI 10.1177/2058460115609635, PubMed 26634147

Eide PK, Sorteberg W (2015)
Outcome of Surgery for Idiopathic Normal Pressure Hydrocephalus: Role of Preoperative Static and Pulsatile Intracranial Pressure
World Neurosurg, 86, 186-193.e1
DOI 10.1016/j.wneu.2015.09.067, PubMed 26428326

Farahmand D, Sæhle T, Eide PK, Tisell M, Hellström P, Wikkelsö C (2015)
A double-blind randomized trial on the clinical effect of different shunt valve settings in idiopathic normal pressure hydrocephalus
J Neurosurg, 124 (2), 359-67
DOI 10.3171/2015.1.JNS141301, PubMed 26315004

Frič R, Eide PK (2015)
Perioperative monitoring of pulsatile and static intracranial pressure in patients with Chiari malformation type 1 undergoing foramen magnum decompression
Acta Neurochir (Wien), 158 (2), 341-7; discussion 346-7
DOI 10.1007/s00701-015-2669-0, PubMed 26711284

Frič R, Eide PK (2015)
Comparison of pulsatile and static pressures within the intracranial and lumbar compartments in patients with Chiari malformation type 1: a prospective observational study
Acta Neurochir (Wien), 157 (8), 1411-23; discussion 1423
DOI 10.1007/s00701-015-2465-x, PubMed 26105759

Ringstad G, Emblem KE, Eide PK (2015)
Phase-contrast magnetic resonance imaging reveals net retrograde aqueductal flow in idiopathic normal pressure hydrocephalus
J Neurosurg, 124 (6), 1850-7
DOI 10.3171/2015.6.JNS15496, PubMed 26636385

Ringstad G, Emblem KE, Geier O, Alperin N, Eide PK (2015)
Aqueductal Stroke Volume: Comparisons with Intracranial Pressure Scores in Idiopathic Normal Pressure Hydrocephalus
AJNR Am J Neuroradiol, 36 (9), 1623-30
DOI 10.3174/ajnr.A4340, PubMed 25977480

Ringstad G, Emblem KE, Geier O, Alperin N, Eide PK (2015)
Reply: To PMID 25977480
AJNR Am J Neuroradiol, 36 (9), 1633-4
DOI 10.3174/ajnr.A4488, PubMed 26251437

Sæhle T, Eide PK (2015)
Characteristics of intracranial pressure (ICP) waves and ICP in children with treatment-responsive hydrocephalus
Acta Neurochir (Wien), 157 (6), 1003-14
DOI 10.1007/s00701-015-2410-z, PubMed 25870129

Sæhle T, Eide PK (2015)
Intracranial pressure monitoring in pediatric and adult patients with hydrocephalus and tentative shunt failure: a single-center experience over 10 years in 146 patients
J Neurosurg, 122 (5), 1076-86
DOI 10.3171/2014.12.JNS141029, PubMed 25679270

Sæhle T, Eide PK (2015)
Association between ventricular volume measures and pulsatile and static intracranial pressure scores in non-communicating hydrocephalus
J Neurol Sci, 350 (1-2), 33-9
DOI 10.1016/j.jns.2015.02.003, PubMed 25680584

Publications 2014

Eide PK, Eidsvaag VA, Hansson HA (2014)
Antisecretory factor (AF) exerts no effects on intracranial pressure (ICP) waves and ICP in patients with idiopathic normal pressure hydrocephalus and idiopathic intracranial hypertension
J Neurol Sci, 343 (1-2), 132-7
DOI 10.1016/j.jns.2014.05.054, PubMed 24928077

Eide PK, Pripp AH (2014)
Increased prevalence of cardiovascular disease in idiopathic normal pressure hydrocephalus patients compared to a population-based cohort from the HUNT3 survey
Fluids Barriers CNS, 11, 19
DOI 10.1186/2045-8118-11-19, PubMed 25180074

Eide PK, Sorteberg A, Meling TR, Sorteberg W (2014)
Baseline pressure errors (BPEs) extensively influence intracranial pressure scores: results of a prospective observational study
Biomed Eng Online, 13, 7
DOI 10.1186/1475-925X-13-7, PubMed 24472296

Eide PK, Sorteberg A, Meling TR, Sorteberg W (2014)
The effect of baseline pressure errors on an intracranial pressure-derived index: results of a prospective observational study
Biomed Eng Online, 13, 99
DOI 10.1186/1475-925X-13-99, PubMed 25052470

Erixon HO, Sorteberg A, Sorteberg W, Eide PK (2014)
Predictors of shunt dependency after aneurysmal subarachnoid hemorrhage: results of a single-center clinical trial
Acta Neurochir (Wien), 156 (11), 2059-69
DOI 10.1007/s00701-014-2200-z, PubMed 25143185

Hommelstad J, Madsø A, Eide PK (2014)
Response to validity of the results of a perioperative protocol to reduce shunt infections
Acta Neurochir (Wien), 156 (4), 791
DOI 10.1007/s00701-014-2016-x, PubMed 24557450

Sandell T, Ringstad GA, Eide PK (2014)
Usefulness of the endoscope in microvascular decompression for trigeminal neuralgia and MRI-based prediction of the need for endoscopy
Acta Neurochir (Wien), 156 (10), 1901-9; discussion 1909
DOI 10.1007/s00701-014-2171-0, PubMed 25008460

Sæhle T, Farahmand D, Eide PK, Tisell M, Wikkelsö C (2014)
A randomized controlled dual-center trial on shunt complications in idiopathic normal-pressure hydrocephalus treated with gradually reduced or "fixed" pressure valve settings
J Neurosurg, 121 (5), 1257-63
DOI 10.3171/2014.7.JNS14283, PubMed 25192478

Publications 2013

Eide PK, Sorteberg AG, Meling TR, Sorteberg W (2013)
Directional intraoperative Doppler ultrasonography during surgery on cranial dural arteriovenous fistulas
Neurosurgery, 73 (2 Suppl Operative), ons211-22; discussion ons222-3
DOI 10.1227/NEU.0000000000000061, PubMed 23839518

Eide PK, Sorteberg W (2013)
An intracranial pressure-derived index monitored simultaneously from two separate sensors in patients with cerebral bleeds: comparison of findings
Biomed Eng Online, 12, 14
DOI 10.1186/1475-925X-12-14, PubMed 23405985

Sandel T, Eide PK (2013)
Long-term results of microvascular decompression for trigeminal neuralgia and hemifacial spasms according to preoperative symptomatology
Acta Neurochir (Wien), 155 (9), 1681-92; discussion 1692
DOI 10.1007/s00701-013-1816-8, PubMed 23873123

Sandell T, Holmen J, Eide PK (2013)
Hypertension in patients with cranial nerve vascular compression syndromes and comparison with a population-based cohort
J Neurosurg, 119 (5), 1302-8
DOI 10.3171/2013.7.JNS13231, PubMed 23991839

Publications 2012

Eide PK, Holm S, Sorteberg W (2012)
Simultaneous monitoring of static and dynamic intracranial pressure parameters from two separate sensors in patients with cerebral bleeds: comparison of findings
Biomed Eng Online, 11, 66
DOI 10.1186/1475-925X-11-66, PubMed 22958653

Eide PK, Sorteberg A, Bentsen G, Marthinsen PB, Stubhaug A, Sorteberg W (2012)
Pressure-derived versus pressure wave amplitude-derived indices of cerebrovascular pressure reactivity in relation to early clinical state and 12-month outcome following aneurysmal subarachnoid hemorrhage
J Neurosurg, 116 (5), 961-71
DOI 10.3171/2012.1.JNS111313, PubMed 22324419

Hommelstad J, Madsø A, Eide PK (2012)
Significant reduction of shunt infection rate in children below 1 year of age after implementation of a perioperative protocol
Acta Neurochir (Wien), 155 (3), 523-31
DOI 10.1007/s00701-012-1574-z, PubMed 23224578

Park EH, Eide PK, Zurakowski D, Madsen JR (2012)
Impaired pulsation absorber mechanism in idiopathic normal pressure hydrocephalus: laboratory investigation
J Neurosurg, 117 (6), 1189-96
DOI 10.3171/2012.9.JNS121227, PubMed 23061391

Publications 2011

Eide PK (2011)
Cardiac output in idiopathic normal pressure hydrocephalus: association with arterial blood pressure and intracranial pressure wave amplitudes and outcome of shunt surgery
Fluids Barriers CNS, 8 (1), 11
DOI 10.1186/2045-8118-8-11, PubMed 21349148

Eide PK, Bakken A (2011)
The baseline pressure of intracranial pressure (ICP) sensors can be altered by electrostatic discharges
Biomed Eng Online, 10, 75
DOI 10.1186/1475-925X-10-75, PubMed 21859487

Eide PK, Bentsen G, Sorteberg AG, Marthinsen PB, Stubhaug A, Sorteberg W (2011)
A randomized and blinded single-center trial comparing the effect of intracranial pressure and intracranial pressure wave amplitude-guided intensive care management on early clinical state and 12-month outcome in patients with aneurysmal subarachnoid hemorrhage
Neurosurgery, 69 (5), 1105-15
DOI 10.1227/NEU.0b013e318227e0e1, PubMed 21670714

Eide PK, Sroka M, Wozniak A, Sæhle T (2011)
Morphological characterization of cardiac induced intracranial pressure (ICP) waves in patients with overdrainage of cerebrospinal fluid and negative ICP
Med Eng Phys, 34 (8), 1066-70
DOI 10.1016/j.medengphy.2011.11.011, PubMed 22153319

Wagshul ME, Eide PK, Madsen JR (2011)
The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility
Fluids Barriers CNS, 8 (1), 5
DOI 10.1186/2045-8118-8-5, PubMed 21349153

Publications 2010

Eide PK, Brean A (2010)
Cerebrospinal fluid pulse pressure amplitude during lumbar infusion in idiopathic normal pressure hydrocephalus can predict response to shunting
Cerebrospinal Fluid Res, 7, 5
DOI 10.1186/1743-8454-7-5, PubMed 20205911

Eide PK, Kerty E (2010)
Static and pulsatile intracranial pressure in idiopathic intracranial hypertension
Clin Neurol Neurosurg, 113 (2), 123-8
DOI 10.1016/j.clineuro.2010.10.008, PubMed 21075509

Eide PK, Park EH, Madsen JR (2010)
Arterial blood pressure vs intracranial pressure in normal pressure hydrocephalus
Acta Neurol Scand, 122 (4), 262-9
DOI 10.1111/j.1600-0404.2009.01304.x, PubMed 20070274

Eide PK, Rapoport BI, Gormley WB, Madsen JR (2010)
A dynamic nonlinear relationship between the static and pulsatile components of intracranial pressure in patients with subarachnoid hemorrhage
J Neurosurg, 112 (3), 616-25
DOI 10.3171/2009.7.JNS081593, PubMed 19731984

Eide PK, Saehle T (2010)
Is ventriculomegaly in idiopathic normal pressure hydrocephalus associated with a transmantle gradient in pulsatile intracranial pressure?
Acta Neurochir (Wien), 152 (6), 989-95
DOI 10.1007/s00701-010-0605-x, PubMed 20130957

Eide PK, Sorteberg W (2010)
Diagnostic intracranial pressure monitoring and surgical management in idiopathic normal pressure hydrocephalus: a 6-year review of 214 patients
Neurosurgery, 66 (1), 80-91
DOI 10.1227/01.NEU.0000363408.69856.B8, PubMed 20023540

Eide PK, Sorteberg W (2010)
Simultaneous measurements of intracranial pressure parameters in the epidural space and in brain parenchyma in patients with hydrocephalus
J Neurosurg, 113 (6), 1317-25
DOI 10.3171/2010.7.JNS10483, PubMed 20799859

Eide PK, Stanisic M (2010)
Cerebral microdialysis and intracranial pressure monitoring in patients with idiopathic normal-pressure hydrocephalus: association with clinical response to extended lumbar drainage and shunt surgery
J Neurosurg, 112 (2), 414-24
DOI 10.3171/2009.5.JNS09122, PubMed 19538048

Frič R, Eide PK (2010)
The presigmoid approach for removal of tumours causing ventral compression of the brainstem. Surgical results and postoperative quality of life
Br J Neurosurg, 25 (1), 86-93
DOI 10.3109/02688697.2010.525266, PubMed 20979440

Sandell T, Eide PK (2010)
The effect of microvascular decompression in patients with multiple sclerosis and trigeminal neuralgia
Neurosurgery, 67 (3), 749-53; discussion 753-4
DOI 10.1227/01.NEU.0000375491.81803.5D, PubMed 20651626

Publications 2009

Brean A, Eide PK (2009)
Lumbar infusion testing in the selection of patients with normal pressure hydrocephalus for surgery
Eur. J. Neurol., 16 (2), E8

Brean A, Fredø HL, Sollid S, Müller T, Sundstrøm T, Eide PK (2009)
Five-year incidence of surgery for idiopathic normal pressure hydrocephalus in Norway
Acta Neurol Scand, 120 (5), 314-6
DOI 10.1111/j.1600-0404.2009.01250.x, PubMed 19832773

Holm S, Eide PK (2009)
Impact of sampling rate for time domain analysis of continuous intracranial pressure (ICP) signals
Med Eng Phys, 31 (5), 601-6
DOI 10.1016/j.medengphy.2008.12.001, PubMed 19185527

Publications 2008

Bentsen G, Stubhaug A, Eide PK (2008)
Differential effects of osmotherapy on static and pulsatile intracranial pressure
Crit Care Med, 36 (8), 2414-9
DOI 10.1097/CCM.0b013e318180fe04, PubMed 18596629

Brean A, Eide PK (2008)
Prevalence of probable idiopathic normal pressure hydrocephalus in a Norwegian population
Acta Neurol Scand, 118 (1), 48-53
DOI 10.1111/j.1600-0404.2007.00982.x, PubMed 18205881

Brean A, Eide PK (2008)
Assessment of idiopathic normal pressure patients in neurological practice: the role of lumbar infusion testing for referral of patients to neurosurgery
Eur J Neurol, 15 (6), 605-12
DOI 10.1111/j.1468-1331.2008.02134.x, PubMed 18410369

Daley ML, Narayanan N, Leffler CW, Eide PK (2008)
Stroke with subarachnoid hemorrhage: assessment of cerebrovascular pressure regulation and simulated cerebrovascular resistance
Acta Neurochir Suppl, 102, 321-5
DOI 10.1007/978-3-211-85578-2_61, PubMed 19388338

Eide PK (2008)
Demonstration of uneven distribution of intracranial pulsatility in hydrocephalus patients
J Neurosurg, 109 (5), 912-7
DOI 10.3171/JNS/2008/109/11/0912, PubMed 18976084

Eide PK, Sorteberg W (2008)
Changes in intracranial pulse pressure amplitudes after shunt implantation and adjustment of shunt valve opening pressure in normal pressure hydrocephalus
Acta Neurochir (Wien), 150 (11), 1141-7; discussion 1147
DOI 10.1007/s00701-008-0138-8, PubMed 18936877

Sandell T, Eide PK (2008)
Effect of microvascular decompression in trigeminal neuralgia patients with or without constant pain
Neurosurgery, 63 (1), 93-9; discussion 99-100
DOI 10.1227/01.NEU.0000335075.16858.EF, PubMed 18728573

Solheim O, Vik A, Gulati S, Eide PK (2008)
Rapid and severe rise in static and pulsatile intracranial pressures during a generalized epileptic seizure
Seizure, 17 (8), 740-3
DOI 10.1016/j.seizure.2008.05.006, PubMed 18554932

Sorteberg W, Slettebø H, Eide PK, Stubhaug A, Sorteberg A (2008)
Surgical treatment of aneurysmal subarachnoid haemorrhage in the presence of 24-h endovascular availability: management and results
Br J Neurosurg, 22 (1), 53-62
DOI 10.1080/02688690701593553, PubMed 17852110

Publications 2007

Eide PK (2007)
Comparison of simultaneous continuous intracranial pressure (ICP) signals from ICP sensors placed within the brain parenchyma and the epidural space
Med Eng Phys, 30 (1), 34-40
DOI 10.1016/j.medengphy.2007.01.005, PubMed 17336574

Eide PK, Bentsen G, Stanisic M, Stubhaug A (2007)
Association between intracranial pulse pressure levels and brain energy metabolism in a patient with an aneurysmal subarachnoid haemorrhage
Acta Anaesthesiol Scand, 51 (9), 1273-6
DOI 10.1111/j.1399-6576.2007.01433.x, PubMed 17714572

Eide PK, Czosnyka M, Sorteberg W, Pickard JD, Smielewski P (2007)
Association between intracranial, arterial pulse pressure amplitudes and cerebral autoregulation in head injury patients
Neurol Res, 29 (6), 578-82
DOI 10.1179/016164107X172167, PubMed 17535570

Eide PK, Egge A, Due-Tønnessen BJ, Helseth E (2007)
Is intracranial pressure waveform analysis useful in the management of pediatric neurosurgical patients?
Pediatr Neurosurg, 43 (6), 472-81
DOI 10.1159/000108790, PubMed 17992035

Eide PK, Sorteberg W (2007)
Association among intracranial compliance, intracranial pulse pressure amplitude and intracranial pressure in patients with intracranial bleeds
Neurol Res, 29 (8), 798-802
DOI 10.1179/016164107X224132, PubMed 17601366

Eide PK, Sorteberg W, Meling T, Jörum E, Hald J, Stubhaug A (2007)
From intracranial pressure to intracranial pressure wave-guided intensive care management of a patient with an aneurysmal subarachnoid haemorrhage
Acta Anaesthesiol Scand, 51 (4), 501-4
DOI 10.1111/j.1399-6576.2007.01269.x, PubMed 17378790

Heuser K, Kerty E, Eide PK, Cvancarova M, Dietrichs E (2007)
Microvascular decompression for hemifacial spasm: postoperative neurologic follow-up and evaluation of life quality
Eur J Neurol, 14 (3), 335-40
DOI 10.1111/j.1468-1331.2006.01670.x, PubMed 17355557

Holm S, Eide PK (2007)
The frequency domain versus time domain methods for processing of intracranial pressure (ICP) signals
Med Eng Phys, 30 (2), 164-70
DOI 10.1016/j.medengphy.2007.03.003, PubMed 17468029

Meling TR, Tiller C, Due-Tønnessen BJ, Egge A, Eide PK, Frøslie KF, Lundar T, Helseth E (2007)
Audits can improve neurosurgical practice--illustrated by endoscopic third ventriculostomy
Pediatr Neurosurg, 43 (6), 482-7
DOI 10.1159/000108791, PubMed 17992036

Publications 2006

Brean A, Eide PK, Stubhaug A (2006)
Comparison of intracranial pressure measured simultaneously within the brain parenchyma and cerebral ventricles
J Clin Monit Comput, 20 (6), 411-4
DOI 10.1007/s10877-006-9047-7, PubMed 17016744

Eide PK (2006)
Assessment of quality of continuous intracranial pressure recordings in children
Pediatr Neurosurg, 42 (1), 28-34
DOI 10.1159/000089506, PubMed 16357498

Eide PK, Brean A (2006)
Lumbar cerebrospinal fluid pressure waves versus intracranial pressure waves in idiopathic normal pressure hydrocephalus
Br J Neurosurg, 20 (6), 407-14
DOI 10.1080/02688690601047312, PubMed 17439094

Eide PK, Brean A (2006)
Intracranial pulse pressure amplitude levels determined during preoperative assessment of subjects with possible idiopathic normal pressure hydrocephalus
Acta Neurochir (Wien), 148 (11), 1151-6; discussion 1156
DOI 10.1007/s00701-006-0896-0, PubMed 17039303

Eide PK, Sorteberg W (2006)
Intracranial pressure levels and single wave amplitudes, Glasgow Coma Score and Glasgow Outcome Score after subarachnoid haemorrhage
Acta Neurochir (Wien), 148 (12), 1267-75; discussion 1275-6
DOI 10.1007/s00701-006-0908-0, PubMed 17123038

Foss T, Eide PK, Finset A (2006)
Intracranial pressure parameters in idiopathic normal pressure hydrocephalus patients with or without improvement of cognitive function after shunt treatment
Dement Geriatr Cogn Disord, 23 (1), 47-54
DOI 10.1159/000096683, PubMed 17077633

Publications 2005

Eide PK (2005)
Assessment of childhood intracranial pressure recordings using a new method of processing intracranial pressure signals
Pediatr Neurosurg, 41 (3), 122-30
DOI 10.1159/000085868, PubMed 15995328

Eide PK (2005)
Comparison of simultaneous continuous intracranial pressure (ICP) signals from a Codman and a Camino ICP sensor
Med Eng Phys, 28 (6), 542-9
DOI 10.1016/j.medengphy.2005.09.003, PubMed 16253539

Eide PK (2005)
A new method for processing of continuous intracranial pressure signals
Med Eng Phys, 28 (6), 579-87
DOI 10.1016/j.medengphy.2005.09.008, PubMed 16275153

Eide PK (2005)
Intracranial pressure parameters in idiopathic normal pressure hydrocephalus patients treated with ventriculo-peritoneal shunts
Acta Neurochir (Wien), 148 (1), 21-9; discussion 29
DOI 10.1007/s00701-005-0654-8, PubMed 16284706

Eide PK, Sorteberg W (2005)
Preoperative spinal hydrodynamics versus clinical change 1 year after shunt treatment in idiopathic normal pressure hydrocephalus patients
Br J Neurosurg, 19 (6), 475-83
DOI 10.1080/02688690500495125, PubMed 16574559

Publications 2004

Sorteberg A, Eide PK, Fremming AD (2004)
A prospective study on the clinical effect of surgical treatment of normal pressure hydrocephalus: the value of hydrodynamic evaluation
Br J Neurosurg, 18 (2), 149-57
DOI 10.1080/02688690410001681000, PubMed 15176556

Publications 2003

Amthor KF, Eide PK (2003)
[Glossopharyngeal neuralgia]
Tidsskr Nor Laegeforen, 123 (23), 3381-3
PubMed 14713973

Eide PK (2003)
Quantitative analysis of continuous intracranial pressure recordings in symptomatic patients with extracranial shunts
J Neurol Neurosurg Psychiatry, 74 (2), 231-7
DOI 10.1136/jnnp.74.2.231, PubMed 12531957

Eide PK (2003)
The relationship between intracranial pressure and size of cerebral ventricles assessed by computed tomography
Acta Neurochir (Wien), 145 (3), 171-9; discussion 179
DOI 10.1007/s00701-002-1062-y, PubMed 12632112

Eide PK, Fremming AD (2003)
A computer-based method for comparisons of continuous intracranial pressure recordings within individual cases
Acta Neurochir (Wien), 145 (5), 351-7; discussion 357-8
DOI 10.1007/s00701-003-0029-y, PubMed 12820041

Eide PK, Fremming AD, Sorteberg A (2003)
Lack of relationship between resistance to cerebrospinal fluid outflow and intracranial pressure in normal pressure hydrocephalus
Acta Neurol Scand, 108 (6), 381-8
DOI 10.1034/j.1600-0404.2003.00163.x, PubMed 14616289

Publications 2002

Eide PK, Due-Tønnessen B, Helseth E, Lundar T (2002)
Differences in quantitative characteristics of intracranial pressure in hydrocephalic children treated surgically or conservatively
Pediatr Neurosurg, 36 (6), 304-13
DOI 10.1159/000063534, PubMed 12077475

Eide PK, Helseth E, Due-Tønnessen B, Lundar T (2002)
Assessment of continuous intracranial pressure recordings in childhood craniosynostosis
Pediatr Neurosurg, 37 (6), 310-20
DOI 10.1159/000066311, PubMed 12422046

Helseth E, Due-Tønnessen B, Egge A, Eide PK, Meling T, Lundar T, Frøslie KF (2002)
[Treatment of hydrocephalus with endoscopic third ventriculocisternostomy]
Tidsskr Nor Laegeforen, 122 (10), 994-8
PubMed 12082709

Publications 2001

Eide PK, Due-Tønnessen B, Helseth E, Lundar T (2001)
Assessment of intracranial pressure volume relationships in childhood: the lumbar infusion test versus intracranial pressure monitoring
Childs Nerv Syst, 17 (7), 382-90
DOI 10.1007/s003810000437, PubMed 11465790

Eide PK, Fremming AD (2001)
A new method and software for quantitative analysis of continuous intracranial pressure recordings
Acta Neurochir (Wien), 143 (12), 1237-47
DOI 10.1007/s007010100020, PubMed 11810388

Eide PK, Helseth E, Due-Tønnessen B, Lundar T (2001)
Changes in intracranial pressure after calvarial expansion surgery in children with slit ventricle syndrome
Pediatr Neurosurg, 35 (4), 195-204
DOI 10.1159/000050421, PubMed 11694797

Publications 2000

Eide PK (2000)
Wind-up and the NMDA receptor complex from a clinical perspective
Eur J Pain, 4 (1), 5-15
DOI 10.1053/eujp.1999.0154, PubMed 10833550

Publications 1998

Eide PK (1998)
Pathophysiological mechanisms of central neuropathic pain after spinal cord injury
Spinal Cord, 36 (9), 601-12
DOI 10.1038/sj.sc.3100737, PubMed 9773443

Eide PK, Rabben T (1998)
Trigeminal neuropathic pain: pathophysiological mechanisms examined by quantitative assessment of abnormal pain and sensory perception
Neurosurgery, 43 (5), 1103-10
DOI 10.1097/00006123-199811000-00055, PubMed 9802854

Eide PK, Rabben T, Skjelbred P, Stubhaug A (1998)
The effect of peripheral glycerol on trigeminal neuropathic pain examined by quantitative assessment of abnormal pain and sensory perception
Acta Neurochir (Wien), 140 (12), 1271-7
DOI 10.1007/s007010050249, PubMed 9932128

Eide PK, Slettebø H (1998)
[Vascular compression and cranial nerve diseases]
Tidsskr Nor Laegeforen, 118 (26), 4079-84
PubMed 9844512

Eide PK, Stubhaug A (1998)
Relief of trigeminal neuralgia after percutaneous retrogasserian glycerol rhizolysis is dependent on normalization of abnormal temporal summation of pain, without general impairment of sensory perception
Neurosurgery, 43 (3), 462-72; discussion 472-4
DOI 10.1097/00006123-199809000-00036, PubMed 9733301

Publications 1997

Eide PK, Stubhaug A (1997)
Sensory perception in patients with trigeminal neuralgia: effects of percutaneous retrogasserian glycerol rhizotomy
Stereotact Funct Neurosurg, 68 (1-4 Pt 1), 207-11
DOI 10.1159/000099925, PubMed 9711718

Eide PK, Stubhaug A (1997)
Relief of glossopharyngeal neuralgia by ketamine-induced N-methyl-aspartate receptor blockade
Neurosurgery, 41 (2), 505-8
DOI 10.1097/00006123-199708000-00043, PubMed 9257324

Eide PK, Stubhaug A, Breivik H, Oye I (1997)
Reply to S.T. Meller: Ketamine: relief from chronic pain through actions at the NMDA receptor
Pain, 72 (1-2), 289-91
PubMed 9272819

Slettebø H, Eide PK (1997)
A prospective study of microvascular decompression for trigeminal neuralgia
Acta Neurochir (Wien), 139 (5), 421-5
DOI 10.1007/BF01808878, PubMed 9204111

Stubhaug A, Breivik H, Eide PK, Kreunen M, Foss A (1997)
Mapping of punctuate hyperalgesia around a surgical incision demonstrates that ketamine is a powerful suppressor of central sensitization to pain following surgery
Acta Anaesthesiol Scand, 41 (9), 1124-32
DOI 10.1111/j.1399-6576.1997.tb04854.x, PubMed 9366932

Publications 1996

Eide PK, Jørum E, Stenehjem AE (1996)
Somatosensory findings in patients with spinal cord injury and central dysaesthesia pain
J Neurol Neurosurg Psychiatry, 60 (4), 411-5
DOI 10.1136/jnnp.60.4.411, PubMed 8774406

Publications 1995

Eide PK, Stubhaug A, Stenehjem AE (1995)
Central dysesthesia pain after traumatic spinal cord injury is dependent on N-methyl-D-aspartate receptor activation
Neurosurgery, 37 (6), 1080-7
DOI 10.1227/00006123-199512000-00007, PubMed 8584148

Publications 1994

Eide PK, Jørum E, Stubhaug A, Bremnes J, Breivik H (1994)
Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo
Pain, 58 (3), 347-54
DOI 10.1016/0304-3959(94)90129-5, PubMed 7838584

Eide PK, Skullerud K (1994)
[Teratoma of the medullary cone as a cause of peripheral polyneuropathy]
Tidsskr Nor Laegeforen, 114 (10), 1185-6
PubMed 8209315

Publications 1993

Eide PK (1993)
[New views on pathogenesis and treatment of pain caused by nerve injury]
Tidsskr Nor Laegeforen, 113 (23), 2917-20
PubMed 8236196

Eide PK, Hole K (1993)
The role of 5-hydroxytryptamine (5-HT) receptor subtypes and plasticity in the 5-HT systems in the regulation of nociceptive sensitivity
Cephalalgia, 13 (2), 75-85
DOI 10.1046/j.1468-2982.1993.1302075.x, PubMed 7684323

Eide PK, Tysnes OB (1993)
[The significance of radiologically diagnosed brain concussion for the outcome after head injury]
Tidsskr Nor Laegeforen, 113 (10), 1227-9
PubMed 8493653

Publications 1992

Eide PK (1992)
Stimulation of 5-HT1 receptors in the spinal cord changes substance P-induced behaviour
Neuropharmacology, 31 (6), 541-5
DOI 10.1016/0028-3908(92)90185-R, PubMed 1383863

Eide PK, Hole K, Broch OJ (1992)
Supersensitivity to the antinociceptive effect of a 5-HT1 receptor agonist after lesion of raphe-spinal serotonergic neurones
Pharmacol Toxicol, 71 (1), 62-4
DOI 10.1111/j.1600-0773.1992.tb00522.x, PubMed 1523196

Eide PK, Tysnes OB (1992)
Early and late outcome in head injury patients with radiological evidence of brain damage
Acta Neurol Scand, 86 (2), 194-8
DOI 10.1111/j.1600-0404.1992.tb05065.x, PubMed 1414231

Mjellem N, Lund A, Eide PK, Størkson R, Tjølsen A (1992)
The role of 5-HT1A and 5-HT1B receptors in spinal nociceptive transmission and in the modulation of NMDA induced behaviour
Neuroreport, 3 (12), 1061-4
DOI 10.1097/00001756-199212000-00007, PubMed 1337283

Publications 1991

Eide PK, Hole K (1991)
Different role of 5-HT1A and 5-HT2 receptors in spinal cord in the control of nociceptive responsiveness
Neuropharmacology, 30 (7), 727-31
DOI 10.1016/0028-3908(91)90180-J, PubMed 1717872

Eide PK, Hole K (1991)
Interactions between serotonin and substance P in the spinal regulation of nociception
Brain Res, 550 (2), 225-30
DOI 10.1016/0006-8993(91)91322-R, PubMed 1715803

Eide PK, Joly NM, Lund A (1991)
The behavioural response to intrathecal serotonin is changed by acute but not by repeated treatment with zimelidine or metergoline
Pharmacol Toxicol, 69 (5), 361-4
DOI 10.1111/j.1600-0773.1991.tb01311.x, PubMed 1839446

Publications 1990

Eide PK (1990)
[Pain surgery seen from the physiologic point of view]
Tidsskr Nor Laegeforen, 110 (14), 1812-4
PubMed 2363142

Eide PK (1990)
Effects of intrathecal substance P and a substance P antagonist on a reflex to noxious heat are independent of changes in tail skin temperature
Acta Physiol Scand, 140 (4), 539-43
DOI 10.1111/j.1748-1716.1990.tb09031.x, PubMed 1707212

Eide PK, Joly NM, Hole K (1990)
The role of spinal cord 5-HT1A and 5-HT1B receptors in the modulation of a spinal nociceptive reflex
Brain Res, 536 (1-2), 195-200
PubMed 2150769

Hole K, Berge OG, Tjølsen A, Eide PK, Garcia-Cabrera I, Lund A, Rosland JH (1990)
The tail-flick test needs to be improved
Pain, 43 (3), 391-3
DOI 10.1016/0304-3959(90)90039-G, PubMed 2293148

Publications 1989

Eide PK, Hole K (1989)
Subsensitivity of serotonin and substance P receptors involved in nociception after repeated administration of a serotonin receptor agonist
J Neural Transm, 77 (1), 1-10
PubMed 2545812

Eide PK, Rosland JH (1989)
The role of tail skin temperature in the facilitation of the tail-flick reflex after spinal transection or interference with descending serotonergic neurotransmission
Acta Physiol Scand, 135 (4), 427-33
DOI 10.1111/j.1748-1716.1989.tb08600.x, PubMed 2544077

Tjølsen A, Lund A, Eide PK, Berge OG, Hole K (1989)
The apparent hyperalgesic effect of a serotonin antagonist in the tail flick test is mainly due to increased tail skin temperature
Pharmacol Biochem Behav, 32 (3), 601-5
DOI 10.1016/0091-3057(89)90004-X, PubMed 2740416

Publications 1988

Eide PK, Berge OG, Tjølsen A, Hole K (1988)
Apparent hyperalgesia in the mouse tail-flick test due to increased tail skin temperature after lesioning of serotonergic pathways
Acta Physiol Scand, 134 (3), 413-20
DOI 10.1111/j.1748-1716.1988.tb08509.x, PubMed 2976242

Eide PK, Hole K (1988)
Intrathecal substance P modulates the depressant effect of 5-methoxy-N,N-dimethyltryptamine on a reflex response to radiant heat in mice
Neurosci Lett, 90 (1-2), 203-7
DOI 10.1016/0304-3940(88)90812-9, PubMed 2457854

Eide PK, Hole K (1988)
Increased behavioural response to intrathecal serotonin after lesion of serotonergic pathways with 5,7-dihydroxytryptamine seems not to be due to depletion of serotonin
Acta Physiol Scand, 134 (2), 291-4
DOI 10.1111/j.1748-1716.1988.tb08491.x, PubMed 2976239

Eide PK, Hole K (1988)
Acute and chronic treatment with selective serotonin uptake inhibitors in mice: effects on nociceptive sensitivity and response to 5-methoxy-N,N-dimethyltryptamine
Pain, 32 (3), 333-40
DOI 10.1016/0304-3959(88)90045-0, PubMed 2966334

Eide PK, Hole K, Berge OG (1988)
Mechanisms by which the putative serotonin receptor antagonist metitepin alters nociception in mice
J Neural Transm, 73 (1), 31-41
PubMed 2969948

Eide PK, Hole K, Berge OG, Broch OJ (1988)
5-HT depletion with 5,7-DHT, PCA and PCPA in mice: differential effects on the sensitivity to 5-MeODMT, 8-OH-DPAT and 5-HTP as measured by two nociceptive tests
Brain Res, 440 (1), 42-52
DOI 10.1016/0006-8993(88)91157-2, PubMed 2965956

Eide PK, Hole K, Broch OJ (1988)
Increased behavioural response to intrathecal substance P after intracerebroventricular 5,7-dihydroxytryptamine but not after p-chlorophenylalanine administration
Acta Physiol Scand, 132 (3), 419-23
DOI 10.1111/j.1748-1716.1988.tb08346.x, PubMed 2465667

Eide PK, Tjølsen A (1988)
Effects of serotonin receptor antagonists and agonists on the tail-flick response in mice involve altered tail-skin temperature
Neuropharmacology, 27 (9), 889-93
DOI 10.1016/0028-3908(88)90115-3, PubMed 2972938

Tjølsen A, Berge OG, Eide PK, Broch OJ, Hole K (1988)
Apparent hyperalgesia after lesions of the descending serotonergic pathways is due to increased tail skin temperature
Pain, 33 (2), 225-31
DOI 10.1016/0304-3959(88)90094-2, PubMed 3380562

Publications 1987

Eide PK, Berge OG, Hunskaar S (1987)
Test-dependent changes in nociception after administration of the putative serotonin antagonist metitepin in mice
Neuropharmacology, 26 (8), 1121-6
DOI 10.1016/0028-3908(87)90257-7, PubMed 3658119

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