Publications

Publications by Bjørnar Hassel

66 publications found

1. Müller EG, Dahlberg D, Hassel B, Revheim ME, Connelly JP (2024)
   Brain Abscess Causes Brain Damage With Long-Lasting Focal Cerebral Hypoactivity that Correlates With Abscess Size: A Cross-Sectional 18F-Fluoro-Deoxyglucose Positron Emission Tomography Study
   Neurosurgery (in press)
   DOI 10.1227/neu.0000000000003268, PubMed 39526777
2. Rogne AG, Sigurdardottir S, Raudeberg R, Hassel B, Dahlberg D (2024)
   Fatigue and depression at 8 weeks and 1 year after bacterial brain abscess and their relationship with cognitive status
   Neuropsychol Rehabil, 1-24 (in press)
   DOI 10.1080/09602011.2024.2393361, PubMed 39205631
3. Hassel B, Sørnes K, Elsais A, Cordero PR, Frøland AS, Rise F (2024)
   Glyceraldehyde metabolism in mouse brain and the entry of blood-borne glyceraldehyde into the brain
   J Neurochem, 168 (9), 2868-2879
   DOI 10.1111/jnc.16158, PubMed 38922704
4. Rogne AG, Sigurdardottir S, Raudeberg R, Hassel B, Dahlberg D (2024)
   Cognitive and everyday functioning after bacterial brain abscess: a prospective study of functional recovery from 8 weeks to 1 year post-treatment
   Brain Inj, 38 (10), 787-795
   DOI 10.1080/02699052.2024.2347565, PubMed 38676705
5. Dahlberg D, Holm S, Sagen EML, Michelsen AE, Stensland M, de Souza GA, Müller EG, Connelly JP, Revheim ME, Halvorsen B, Hassel B (2023)
   Bacterial Brain Abscesses Expand Despite Effective Antibiotic Treatment: A Process Powered by Osmosis Due to Neutrophil Cell Death
   Neurosurgery, 94 (5), 1079-87 (in press)
   DOI 10.1227/neu.0000000000002792, PubMed 38084989
6. Kildal ESM, Quintana DS, Szabo A, Tronstad C, Andreassen O, Nærland T, Hassel B (2023)
   Heart rate monitoring to detect acute pain in non-verbal patients: a study protocol for a randomized controlled clinical trial
   BMC Psychiatry, 23 (1), 252
   DOI 10.1186/s12888-023-04757-1, PubMed 37060049
7. Jamali A, Kristensen E, Tangeraas T, Arntsen V, Sikiric A, Kupliauskiene G, Myren-Svelstad S, Berland S, Sejersted Y, Gerstner T, Hassel B, Bindoff LA, Brodtkorb E (2023)
   Corrigendum to "The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study" [Epilepsy Res. 190 (2023) 107099]
   Epilepsy Res, 198, 107113
   DOI 10.1016/j.eplepsyres.2023.107113, PubMed 36906427
8. Jamali A, Kristensen E, Tangeraas T, Arntsen V, Sikiric A, Kupliauskiene G, Myren-Svelstad S, Berland S, Sejersted Y, Gerstner T, Hassel B, Bindoff LA, Brodtkorb E (2023)
   The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study
   Epilepsy Res, 190, 107099
   DOI 10.1016/j.eplepsyres.2023.107099, PubMed 36731270
9. Watne LO, Pollmann CT, Neerland BE, Quist-Paulsen E, Halaas NB, Idland AV, Hassel B, Henjum K, Knapskog AB, Frihagen F, Raeder J, Godø A, Ueland PM, McCann A, Figved W, Selbæk G, Zetterberg H, Fang EF, Myrstad M, Giil LM (2023)
   Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients
   J Clin Invest, 133 (2)
   DOI 10.1172/JCI163472, PubMed 36409557
10. Rogne A, Hassel B (2022)
    Improvement of attention deficit/hyperactivity disorder (ADHD) in three adult men during testosterone treatment: a case series
    J Med Case Rep, 16 (1), 425
    DOI 10.1186/s13256-022-03651-w, PubMed 36397172
11. Svae GB, Hassel B, Søndenaa E (2022)
    People with intellectual disabilities and harmful sexual behaviour: Professionals' views on the barriers to prevent harm
    J Appl Res Intellect Disabil, 36 (1), 176-185
    DOI 10.1111/jar.13048, PubMed 36385724
12. Hassel B, Niehusmann P, Halvorsen B, Dahlberg D (2022)
    Pro-inflammatory cytokines in cystic glioblastoma: A quantitative study with a comparison with bacterial brain abscesses. With an MRI investigation of displacement and destruction of the brain tissue surrounding a glioblastoma
    Front Oncol, 12, 846674
    DOI 10.3389/fonc.2022.846674, PubMed 35965529
13. Kildal E, Hassel B, Bjørnebekk A (2022)
    ADHD symptoms and use of anabolic androgenic steroids among male weightlifters
    Sci Rep, 12 (1), 9479
    DOI 10.1038/s41598-022-12977-w, PubMed 35676515
14. Dahlberg D, Rummel J, Distante S, De Souza GA, Stensland ME, Mariussen E, Rootwelt H, Voie Ø, Hassel B (2022)
    Glioblastoma microenvironment contains multiple hormonal and non-hormonal growth-stimulating factors
    Fluids Barriers CNS, 19 (1), 45
    DOI 10.1186/s12987-022-00333-z, PubMed 35659255
15. Henjum K, Godang K, Quist-Paulsen E, Idland AV, Neerland BE, Sandvig H, Brugård A, Raeder J, Frihagen F, Wyller TB, Hassel B, Bollerslev J, Watne LO (2021)
    Cerebrospinal fluid catecholamines in delirium and dementia
    Brain Commun, 3 (3), fcab121
    DOI 10.1093/braincomms/fcab121, PubMed 34423298
16. Eide PK, Mariussen E, Uggerud H, Pripp AH, Lashkarivand A, Hassel B, Christensen H, Hovd MH, Ringstad G (2021)
    Clinical application of intrathecal gadobutrol for assessment of cerebrospinal fluid tracer clearance to blood
    JCI Insight, 6 (9)
    DOI 10.1172/jci.insight.147063, PubMed 33822769
17. Kildal E, Stadskleiv K, Boysen ES, Øderud T, Dahl IL, Seeberg TM, Guldal S, Strisland F, Morland C, Hassel B (2021)
    Increased heart rate functions as a signal of acute distress in non-communicating persons with intellectual disability
    Sci Rep, 11 (1), 6479
    DOI 10.1038/s41598-021-86023-6, PubMed 33742078
18. Rogne AG, Müller EG, Udnaes E, Sigurdardottir S, Raudeberg R, Connelly JP, Revheim ME, Hassel B, Dahlberg D (2020)
    β-Amyloid may accumulate in the human brain after focal bacterial infection: An ¹⁸ F-flutemetamol positron emission tomography study
    Eur J Neurol, 28 (3), 877-883
    DOI 10.1111/ene.14622, PubMed 33131195
19. Zhou Y, Eid T, Hassel B, Danbolt NC (2020)
    Novel aspects of glutamine synthetase in ammonia homeostasis
    Neurochem Int, 140, 104809
    DOI 10.1016/j.neuint.2020.104809, PubMed 32758585
20. Qureshi T, Bjørkmo M, Nordengen K, Gundersen V, Utheim TP, Watne LO, Storm-Mathisen J, Hassel B, Chaudhry FA (2020)
    Slc38a1 Conveys Astroglia-Derived Glutamine into GABAergic Interneurons for Neurotransmitter GABA Synthesis
    Cells, 9 (7)
    DOI 10.3390/cells9071686, PubMed 32668809
21. Sumathipala D, Strømme P, Gilissen C, Einarsen IH, Bjørndalen HJ, Server A, Corominas J, Hassel B, Fannemel M, Misceo D, Frengen E (2020)
    Sudden death in epilepsy and ectopic neurohypophysis in Joubert syndrome 23 diagnosed using SNVs/indels and structural variants pipelines on WGS data: a case report
    BMC Med Genet, 21 (1), 96
    DOI 10.1186/s12881-020-01024-y, PubMed 32381069
22. Qureshi T, Sørensen C, Berghuis P, Jensen V, Dobszay MB, Farkas T, Dalen KT, Guo C, Hassel B, Utheim TP, Hvalby Ø, Hafting T, Harkany T, Fyhn M, Chaudhry FA (2019)
    The Glutamine Transporter Slc38a1 Regulates GABAergic Neurotransmission and Synaptic Plasticity
    Cereb Cortex, 29 (12), 5166-5179
    DOI 10.1093/cercor/bhz055, PubMed 31050701
23. Hassel B, Rogne AG, Hope S (2019)
    Intellectual Disability Associated With Pyridoxine-Responsive Epilepsies: The Need to Protect Cognitive Development
    Front Psychiatry, 10, 116
    DOI 10.3389/fpsyt.2019.00116, PubMed 30930802
24. Holmøy AKT, Johannessen CH, Hope S, van Walsem MR, Aanonsen NO, Hassel B (2019)
    Uncovering health and social care needs among myotonic dystrophy patients: Utility of the Needs and Provisions Complexity Scale
    Acta Neurol Scand, 139 (6), 526-532
    DOI 10.1111/ane.13086, PubMed 30848487
25. Vohra R, Dalgaard LM, Vibaek J, Langbøl MA, Bergersen LH, Olsen NV, Hassel B, Chaudhry FA, Kolko M (2019)
    Potential metabolic markers in glaucoma and their regulation in response to hypoxia
    Acta Ophthalmol, 97 (6), 567-576
    DOI 10.1111/aos.14021, PubMed 30690927
26. Hassel B, Mariussen E, Idland AV, Dahl GT, Ræder J, Frihagen F, Berg JP, Chaudhry FA, Wyller TB, Watne LO (2018)
    CSF sodium at toxic levels precedes delirium in hip fracture patients
    Neurotoxicology, 69, 11-16
    DOI 10.1016/j.neuro.2018.08.010, PubMed 30149051
27. Zhou Y, Dhaher R, Parent M, Hu QX, Hassel B, Yee SP, Hyder F, Gruenbaum SE, Eid T, Danbolt NC (2018)
    Selective deletion of glutamine synthetase in the mouse cerebral cortex induces glial dysfunction and vascular impairment that precede epilepsy and neurodegeneration
    Neurochem Int, 123, 22-33
    DOI 10.1016/j.neuint.2018.07.009, PubMed 30053506
28. Zhou Y, Hassel B, Eid T, Danbolt NC (2018)
    Axon-terminals expressing EAAT2 (GLT-1; Slc1a2) are common in the forebrain and not limited to the hippocampus
    Neurochem Int, 123, 101-113
    DOI 10.1016/j.neuint.2018.03.006, PubMed 29530756
29. Morland C, Frøland AS, Pettersen MN, Storm-Mathisen J, Gundersen V, Rise F, Hassel B (2018)
    Propionate enters GABAergic neurons, inhibits GABA transaminase, causes GABA accumulation and lethargy in a model of propionic acidemia
    Biochem J, 475 (4), 749-758
    DOI 10.1042/BCJ20170814, PubMed 29339464
30. Hu QX, Ottestad-Hansen S, Holmseth S, Hassel B, Danbolt NC, Zhou Y (2018)
    Expression of Glutamate Transporters in Mouse Liver, Kidney, and Intestine
    J Histochem Cytochem, 66 (3), 189-202
    DOI 10.1369/0022155417749828, PubMed 29303644
31. Idland AV, Wyller TB, Støen R, Dahl GT, Frihagen F, Brækhus A, Hassel B, Watne LO (2017)
    Cerebrospinal Fluid Phosphate in Delirium after Hip Fracture
    Dement Geriatr Cogn Dis Extra, 7 (3), 309-317
    DOI 10.1159/000478723, PubMed 29118783
32. Hassel B, De Souza GA, Stensland ME, Ivanovic J, Voie Ø, Dahlberg D (2017)
    The proteome of pus from human brain abscesses: host-derived neurotoxic proteins and the cell-type diversity of CNS pus
    J Neurosurg, 129 (3), 829-837
    DOI 10.3171/2017.4.JNS17284, PubMed 29053067
33. Dahlberg D, Struys EA, Jansen EE, Mørkrid L, Midttun Ø, Hassel B (2017)
    Cyst Fluid From Cystic, Malignant Brain Tumors: A Reservoir of Nutrients, Including Growth Factor-Like Nutrients, for Tumor Cells
    Neurosurgery, 80 (6), 917-924
    DOI 10.1093/neuros/nyw101, PubMed 28327992
34. Moen MN, Fjær R, Hamdani EH, Laerdahl JK, Menchini RJ, Vigeland MD, Sheng Y, Undlien DE, Hassel B, Salih MA, El Khashab HY, Selmer KK, Chaudhry FA (2016)
    Pathogenic variants in KCTD7 perturb neuronal K+ fluxes and glutamine transport
    Brain, 139 (Pt 12), 3109-3120
    DOI 10.1093/brain/aww244, PubMed 27742667
35. Watne LO, Idland AV, Fekkes D, Raeder J, Frihagen F, Ranhoff AH, Chaudhry FA, Engedal K, Wyller TB, Hassel B (2016)
    Increased CSF levels of aromatic amino acids in hip fracture patients with delirium suggests higher monoaminergic activity
    BMC Geriatr, 16, 149
    DOI 10.1186/s12877-016-0324-0, PubMed 27484129
36. Dingledine R, Hassel B (2016)
    A New Approach for Epilepsy
    Cerebrum, 2016
    PubMed 27408679
37. Morland C, Pettersen MN, Hassel B (2016)
    Hyperosmolar sodium chloride is toxic to cultured neurons and causes reduction of glucose metabolism and ATP levels, an increase in glutamate uptake, and a reduction in cytosolic calcium
    Neurotoxicology, 54, 34-43
    DOI 10.1016/j.neuro.2016.03.005, PubMed 26994581
38. Dahlberg D, Ivanovic J, Hassel B (2015)
    Toxic levels of ammonia in human brain abscess
    J Neurosurg, 124 (3), 854-60
    DOI 10.3171/2015.1.JNS142582, PubMed 26274996
39. Solyga VM, Western E, Solheim H, Hassel B, Kerty E (2015)
    [Posterior cortical atrophy]
    Tidsskr Nor Laegeforen, 135 (10), 949-52
    DOI 10.4045/tidsskr.14.1127, PubMed 26037756
40. Dahlberg D, Mariussen E, Goverud IL, Tønjum T, Mæhlen J, Antal EA, Hassel B (2015)
    Staphylococcal α-hemolysin is neurotoxic and causes lysis of brain cells in vivo and in vitro
    Neurotoxicology, 48, 61-7
    DOI 10.1016/j.neuro.2015.03.001, PubMed 25757835
41. Hassel B, Elsais A, Frøland AS, Taubøll E, Gjerstad L, Quan Y, Dingledine R, Rise F (2015)
    Uptake and metabolism of fructose by rat neocortical cells in vivo and by isolated nerve terminals in vitro
    J Neurochem, 133 (4), 572-81
    DOI 10.1111/jnc.13079, PubMed 25708447
42. Dahlberg D, Ivanovic J, Mariussen E, Hassel B (2015)
    High extracellular levels of potassium and trace metals in human brain abscess
    Neurochem Int, 82, 28-32
    DOI 10.1016/j.neuint.2015.02.003, PubMed 25684071
43. Hassel B, Dahlberg D, Mariussen E, Goverud IL, Antal EA, Tønjum T, Maehlen J (2014)
    Brain infection with Staphylococcus aureus leads to high extracellular levels of glutamate, aspartate, γ-aminobutyric acid, and zinc
    J Neurosci Res, 92 (12), 1792-800
    DOI 10.1002/jnr.23444, PubMed 25043715
44. Dahlberg D, Ivanovic J, Hassel B (2014)
    High extracellular concentration of excitatory amino acids glutamate and aspartate in human brain abscess
    Neurochem Int, 69, 41-7
    DOI 10.1016/j.neuint.2014.03.001, PubMed 24632003
45. Hassel B (2012)
    [A description of early hydrocephalus with macrocephaly, cerebral palsy, epilepsy, intellectual disability, and growth retardation by Norwegian novelist Amalie Skram (1846-1905)]
    Tidsskr Nor Laegeforen, 132 (23-24), 2632-5
    DOI 10.4045/tidsskr.12.0912, PubMed 23338097
46. Hassel B (2013)
    Tetanus: pathophysiology, treatment, and the possibility of using botulinum toxin against tetanus-induced rigidity and spasms
    Toxins (Basel), 5 (1), 73-83
    DOI 10.3390/toxins5010073, PubMed 23299659
47. Zhou Y, Holmseth S, Guo C, Hassel B, Höfner G, Huitfeldt HS, Wanner KT, Danbolt NC (2012)
    Deletion of the γ-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents
    J Biol Chem, 287 (42), 35733-35746
    DOI 10.1074/jbc.M112.368175, PubMed 22896705
48. Hassel B, Taubøll E, Shaw R, Gjerstad L, Dingledine R (2010)
    Region-specific changes in gene expression in rat brain after chronic treatment with levetiracetam or phenytoin
    Epilepsia, 51 (9), 1714-20
    DOI 10.1111/j.1528-1167.2010.02545.x, PubMed 20345932
49. Hassel B, Solyga V, Lossius A (2008)
    High-affinity choline uptake and acetylcholine-metabolizing enzymes in CNS white matter. A quantitative study
    Neurochem Int, 53 (6-8), 193-8
    DOI 10.1016/j.neuint.2008.06.008, PubMed 18674580
50. Herrman H, Braekhus A, Aaserud O, Aukrust P, Stubhaug A, Hassel B (2008)
    Early treatment of tetanus-induced trismus with botulinum toxin A
    Anesth Analg, 106 (5), 1591
    DOI 10.1213/ANE.0b013e31816a30f0, PubMed 18420892
51. Hassel B, Tessler S, Faull RL, Emson PC (2007)
    Glutamate uptake is reduced in prefrontal cortex in Huntington's disease
    Neurochem Res, 33 (2), 232-7
    DOI 10.1007/s11064-007-9463-1, PubMed 17726644
52. Bough KJ, Paquet M, Paré JF, Hassel B, Smith Y, Hall RA, Dingledine R (2007)
    Evidence against enhanced glutamate transport in the anticonvulsant mechanism of the ketogenic diet
    Epilepsy Res, 74 (2-3), 232-6
    DOI 10.1016/j.eplepsyres.2007.03.002, PubMed 17416486
53. Henjum S, Hassel B (2007)
    High-affinity glycine and glutamate transport in pig forebrain white and gray matter: a quantitative study
    Neurochem Int, 50 (5), 696-702
    DOI 10.1016/j.neuint.2007.01.002, PubMed 17316904
54. Morland C, Henjum S, Iversen EG, Skrede KK, Hassel B (2007)
    Evidence for a higher glycolytic than oxidative metabolic activity in white matter of rat brain
    Neurochem Int, 50 (5), 703-9
    DOI 10.1016/j.neuint.2007.01.003, PubMed 17316901
55. Nguyen NH, Morland C, Gonzalez SV, Rise F, Storm-Mathisen J, Gundersen V, Hassel B (2007)
    Propionate increases neuronal histone acetylation, but is metabolized oxidatively by glia. Relevance for propionic acidemia
    J Neurochem, 101 (3), 806-14
    DOI 10.1111/j.1471-4159.2006.04397.x, PubMed 17286595
56. Nguyen NH, Gonzalez SV, Hassel B (2007)
    Formation of glycerol from glucose in rat brain and cultured brain cells. Augmentation with kainate or ischemia
    J Neurochem, 101 (6), 1694-700
    DOI 10.1111/j.1471-4159.2006.04433.x, PubMed 17286586
57. Nguyen N, Gonzalez SV, Rise F, Hassel B (2006)
    Cerebral metabolism of glucose and pyruvate in soman poisoning. A 13C nuclear magnetic resonance spectroscopic study
    Neurotoxicology, 28 (1), 13-8
    DOI 10.1016/j.neuro.2006.09.007, PubMed 17087995
58. Henjum S, Hassel B (2006)
    High-affinity GABA uptake and GABA-metabolizing enzymes in pig forebrain white matter: a quantitative study
    Neurochem Int, 50 (2), 365-70
    DOI 10.1016/j.neuint.2006.09.004, PubMed 17069932
59. Bough KJ, Wetherington J, Hassel B, Pare JF, Gawryluk JW, Greene JG, Shaw R, Smith Y, Geiger JD, Dingledine RJ (2006)
    Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet
    Ann Neurol, 60 (2), 223-35
    DOI 10.1002/ana.20899, PubMed 16807920
60. Hassel B (2006)
    Nicotinic mechanisms contribute to soman-induced symptoms and lethality
    Neurotoxicology, 27 (4), 501-7
    DOI 10.1016/j.neuro.2006.01.007, PubMed 16500708
61. Gonzalez SV, Nguyen NH, Rise F, Hassel B (2005)
    Brain metabolism of exogenous pyruvate
    J Neurochem, 95 (1), 284-93
    DOI 10.1111/j.1471-4159.2005.03365.x, PubMed 16181432
62. Morland C, Boldingh KA, Iversen EG, Hassel B (2004)
    Valproate is neuroprotective against malonate toxicity in rat striatum: an association with augmentation of high-affinity glutamate uptake
    J Cereb Blood Flow Metab, 24 (11), 1226-34
    DOI 10.1097/01.WCB.0000138666.25305.A7, PubMed 15545916
63. Hassel B, Boldingh KA, Narvesen C, Iversen EG, Skrede KK (2003)
    Glutamate transport, glutamine synthetase and phosphate-activated glutaminase in rat CNS white matter. A quantitative study
    J Neurochem, 87 (1), 230-7
    DOI 10.1046/j.1471-4159.2003.01984.x, PubMed 12969269
64. Nguyen NH, Bråthe A, Hassel B (2003)
    Neuronal uptake and metabolism of glycerol and the neuronal expression of mitochondrial glycerol-3-phosphate dehydrogenase
    J Neurochem, 85 (4), 831-42
    DOI 10.1046/j.1471-4159.2003.01762.x, PubMed 12716415
65. Hassel B, Bråthe A, Petersen D (2002)
    Cerebral dicarboxylate transport and metabolism studied with isotopically labelled fumarate, malate and malonate
    J Neurochem, 82 (2), 410-9
    DOI 10.1046/j.1471-4159.2002.00986.x, PubMed 12124442
66. Hassel B, Sonnewald U (2002)
    Effects of potassium and glutamine on metabolism of glucose in astrocytes
    Neurochem Res, 27 (1-2), 167-71
    DOI 10.1023/a:1014827327690, PubMed 11926271