Publications

Publications by Bjørnar Hassel

63 publications found

1. Rogne AG, Sigurdardottir S, Raudeberg R, Hassel B, Dahlberg D (2024)
   Cognitive and everyday functioning after bacterial brain abscess: a prospective study of functional recovery from 8 weeks to 1 year post-treatment
   Brain Inj, 1-9 (in press)
   DOI 10.1080/02699052.2024.2347565, PubMed 38676705
2. Dahlberg D, Holm S, Sagen EML, Michelsen AE, Stensland M, de Souza GA, Müller EG, Connelly JP, Revheim ME, Halvorsen B, Hassel B (2023)
   Bacterial Brain Abscesses Expand Despite Effective Antibiotic Treatment: A Process Powered by Osmosis Due to Neutrophil Cell Death
   Neurosurgery, 94 (5), 1079-87 (in press)
   DOI 10.1227/neu.0000000000002792, PubMed 38084989
3. Kildal ESM, Quintana DS, Szabo A, Tronstad C, Andreassen O, Nærland T, Hassel B (2023)
   Heart rate monitoring to detect acute pain in non-verbal patients: a study protocol for a randomized controlled clinical trial
   BMC Psychiatry, 23 (1), 252
   DOI 10.1186/s12888-023-04757-1, PubMed 37060049
4. Jamali A, Kristensen E, Tangeraas T, Arntsen V, Sikiric A, Kupliauskiene G, Myren-Svelstad S, Berland S, Sejersted Y, Gerstner T, Hassel B, Bindoff LA, Brodtkorb E (2023)
   Corrigendum to "The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study" [Epilepsy Res. 190 (2023) 107099]
   Epilepsy Res, 198, 107113
   DOI 10.1016/j.eplepsyres.2023.107113, PubMed 36906427
5. Jamali A, Kristensen E, Tangeraas T, Arntsen V, Sikiric A, Kupliauskiene G, Myren-Svelstad S, Berland S, Sejersted Y, Gerstner T, Hassel B, Bindoff LA, Brodtkorb E (2023)
   The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study
   Epilepsy Res, 190, 107099
   DOI 10.1016/j.eplepsyres.2023.107099, PubMed 36731270
6. Watne LO, Pollmann CT, Neerland BE, Quist-Paulsen E, Halaas NB, Idland AV, Hassel B, Henjum K, Knapskog AB, Frihagen F, Raeder J, Godø A, Ueland PM, McCann A, Figved W, Selbæk G, Zetterberg H, Fang EF, Myrstad M, Giil LM (2023)
   Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients
   J Clin Invest, 133 (2)
   DOI 10.1172/JCI163472, PubMed 36409557
7. Rogne A, Hassel B (2022)
   Improvement of attention deficit/hyperactivity disorder (ADHD) in three adult men during testosterone treatment: a case series
   J Med Case Rep, 16 (1), 425
   DOI 10.1186/s13256-022-03651-w, PubMed 36397172
8. Svae GB, Hassel B, Søndenaa E (2022)
   People with intellectual disabilities and harmful sexual behaviour: Professionals' views on the barriers to prevent harm
   J Appl Res Intellect Disabil, 36 (1), 176-185
   DOI 10.1111/jar.13048, PubMed 36385724
9. Hassel B, Niehusmann P, Halvorsen B, Dahlberg D (2022)
   Pro-inflammatory cytokines in cystic glioblastoma: A quantitative study with a comparison with bacterial brain abscesses. With an MRI investigation of displacement and destruction of the brain tissue surrounding a glioblastoma
   Front Oncol, 12, 846674
   DOI 10.3389/fonc.2022.846674, PubMed 35965529
10. Kildal E, Hassel B, Bjørnebekk A (2022)
    ADHD symptoms and use of anabolic androgenic steroids among male weightlifters
    Sci Rep, 12 (1), 9479
    DOI 10.1038/s41598-022-12977-w, PubMed 35676515
11. Dahlberg D, Rummel J, Distante S, De Souza GA, Stensland ME, Mariussen E, Rootwelt H, Voie Ø, Hassel B (2022)
    Glioblastoma microenvironment contains multiple hormonal and non-hormonal growth-stimulating factors
    Fluids Barriers CNS, 19 (1), 45
    DOI 10.1186/s12987-022-00333-z, PubMed 35659255
12. Henjum K, Godang K, Quist-Paulsen E, Idland AV, Neerland BE, Sandvig H, Brugård A, Raeder J, Frihagen F, Wyller TB, Hassel B, Bollerslev J, Watne LO (2021)
    Cerebrospinal fluid catecholamines in delirium and dementia
    Brain Commun, 3 (3), fcab121
    DOI 10.1093/braincomms/fcab121, PubMed 34423298
13. Eide PK, Mariussen E, Uggerud H, Pripp AH, Lashkarivand A, Hassel B, Christensen H, Hovd MH, Ringstad G (2021)
    Clinical application of intrathecal gadobutrol for assessment of cerebrospinal fluid tracer clearance to blood
    JCI Insight, 6 (9)
    DOI 10.1172/jci.insight.147063, PubMed 33822769
14. Kildal E, Stadskleiv K, Boysen ES, Øderud T, Dahl IL, Seeberg TM, Guldal S, Strisland F, Morland C, Hassel B (2021)
    Increased heart rate functions as a signal of acute distress in non-communicating persons with intellectual disability
    Sci Rep, 11 (1), 6479
    DOI 10.1038/s41598-021-86023-6, PubMed 33742078
15. Rogne AG, Müller EG, Udnaes E, Sigurdardottir S, Raudeberg R, Connelly JP, Revheim ME, Hassel B, Dahlberg D (2020)
    β-Amyloid may accumulate in the human brain after focal bacterial infection: An ¹⁸ F-flutemetamol positron emission tomography study
    Eur J Neurol, 28 (3), 877-883
    DOI 10.1111/ene.14622, PubMed 33131195
16. Zhou Y, Eid T, Hassel B, Danbolt NC (2020)
    Novel aspects of glutamine synthetase in ammonia homeostasis
    Neurochem Int, 140, 104809
    DOI 10.1016/j.neuint.2020.104809, PubMed 32758585
17. Qureshi T, Bjørkmo M, Nordengen K, Gundersen V, Utheim TP, Watne LO, Storm-Mathisen J, Hassel B, Chaudhry FA (2020)
    Slc38a1 Conveys Astroglia-Derived Glutamine into GABAergic Interneurons for Neurotransmitter GABA Synthesis
    Cells, 9 (7)
    DOI 10.3390/cells9071686, PubMed 32668809
18. Sumathipala D, Strømme P, Gilissen C, Einarsen IH, Bjørndalen HJ, Server A, Corominas J, Hassel B, Fannemel M, Misceo D, Frengen E (2020)
    Sudden death in epilepsy and ectopic neurohypophysis in Joubert syndrome 23 diagnosed using SNVs/indels and structural variants pipelines on WGS data: a case report
    BMC Med Genet, 21 (1), 96
    DOI 10.1186/s12881-020-01024-y, PubMed 32381069
19. Qureshi T, Sørensen C, Berghuis P, Jensen V, Dobszay MB, Farkas T, Dalen KT, Guo C, Hassel B, Utheim TP, Hvalby Ø, Hafting T, Harkany T, Fyhn M, Chaudhry FA (2019)
    The Glutamine Transporter Slc38a1 Regulates GABAergic Neurotransmission and Synaptic Plasticity
    Cereb Cortex, 29 (12), 5166-5179
    DOI 10.1093/cercor/bhz055, PubMed 31050701
20. Hassel B, Rogne AG, Hope S (2019)
    Intellectual Disability Associated With Pyridoxine-Responsive Epilepsies: The Need to Protect Cognitive Development
    Front Psychiatry, 10, 116
    DOI 10.3389/fpsyt.2019.00116, PubMed 30930802
21. Holmøy AKT, Johannessen CH, Hope S, van Walsem MR, Aanonsen NO, Hassel B (2019)
    Uncovering health and social care needs among myotonic dystrophy patients: Utility of the Needs and Provisions Complexity Scale
    Acta Neurol Scand, 139 (6), 526-532
    DOI 10.1111/ane.13086, PubMed 30848487
22. Vohra R, Dalgaard LM, Vibaek J, Langbøl MA, Bergersen LH, Olsen NV, Hassel B, Chaudhry FA, Kolko M (2019)
    Potential metabolic markers in glaucoma and their regulation in response to hypoxia
    Acta Ophthalmol, 97 (6), 567-576
    DOI 10.1111/aos.14021, PubMed 30690927
23. Hassel B, Mariussen E, Idland AV, Dahl GT, Ræder J, Frihagen F, Berg JP, Chaudhry FA, Wyller TB, Watne LO (2018)
    CSF sodium at toxic levels precedes delirium in hip fracture patients
    Neurotoxicology, 69, 11-16
    DOI 10.1016/j.neuro.2018.08.010, PubMed 30149051
24. Zhou Y, Dhaher R, Parent M, Hu QX, Hassel B, Yee SP, Hyder F, Gruenbaum SE, Eid T, Danbolt NC (2018)
    Selective deletion of glutamine synthetase in the mouse cerebral cortex induces glial dysfunction and vascular impairment that precede epilepsy and neurodegeneration
    Neurochem Int, 123, 22-33
    DOI 10.1016/j.neuint.2018.07.009, PubMed 30053506
25. Zhou Y, Hassel B, Eid T, Danbolt NC (2018)
    Axon-terminals expressing EAAT2 (GLT-1; Slc1a2) are common in the forebrain and not limited to the hippocampus
    Neurochem Int, 123, 101-113
    DOI 10.1016/j.neuint.2018.03.006, PubMed 29530756
26. Morland C, Frøland AS, Pettersen MN, Storm-Mathisen J, Gundersen V, Rise F, Hassel B (2018)
    Propionate enters GABAergic neurons, inhibits GABA transaminase, causes GABA accumulation and lethargy in a model of propionic acidemia
    Biochem J, 475 (4), 749-758
    DOI 10.1042/BCJ20170814, PubMed 29339464
27. Hu QX, Ottestad-Hansen S, Holmseth S, Hassel B, Danbolt NC, Zhou Y (2018)
    Expression of Glutamate Transporters in Mouse Liver, Kidney, and Intestine
    J Histochem Cytochem, 66 (3), 189-202
    DOI 10.1369/0022155417749828, PubMed 29303644
28. Idland AV, Wyller TB, Støen R, Dahl GT, Frihagen F, Brækhus A, Hassel B, Watne LO (2017)
    Cerebrospinal Fluid Phosphate in Delirium after Hip Fracture
    Dement Geriatr Cogn Dis Extra, 7 (3), 309-317
    DOI 10.1159/000478723, PubMed 29118783
29. Hassel B, De Souza GA, Stensland ME, Ivanovic J, Voie Ø, Dahlberg D (2017)
    The proteome of pus from human brain abscesses: host-derived neurotoxic proteins and the cell-type diversity of CNS pus
    J Neurosurg, 129 (3), 829-837
    DOI 10.3171/2017.4.JNS17284, PubMed 29053067
30. Dahlberg D, Struys EA, Jansen EE, Mørkrid L, Midttun Ø, Hassel B (2017)
    Cyst Fluid From Cystic, Malignant Brain Tumors: A Reservoir of Nutrients, Including Growth Factor-Like Nutrients, for Tumor Cells
    Neurosurgery, 80 (6), 917-924
    DOI 10.1093/neuros/nyw101, PubMed 28327992
31. Moen MN, Fjær R, Hamdani EH, Laerdahl JK, Menchini RJ, Vigeland MD, Sheng Y, Undlien DE, Hassel B, Salih MA, El Khashab HY, Selmer KK, Chaudhry FA (2016)
    Pathogenic variants in KCTD7 perturb neuronal K+ fluxes and glutamine transport
    Brain, 139 (Pt 12), 3109-3120
    DOI 10.1093/brain/aww244, PubMed 27742667
32. Watne LO, Idland AV, Fekkes D, Raeder J, Frihagen F, Ranhoff AH, Chaudhry FA, Engedal K, Wyller TB, Hassel B (2016)
    Increased CSF levels of aromatic amino acids in hip fracture patients with delirium suggests higher monoaminergic activity
    BMC Geriatr, 16, 149
    DOI 10.1186/s12877-016-0324-0, PubMed 27484129
33. Dingledine R, Hassel B (2016)
    A New Approach for Epilepsy
    Cerebrum, 2016
    PubMed 27408679
34. Morland C, Pettersen MN, Hassel B (2016)
    Hyperosmolar sodium chloride is toxic to cultured neurons and causes reduction of glucose metabolism and ATP levels, an increase in glutamate uptake, and a reduction in cytosolic calcium
    Neurotoxicology, 54, 34-43
    DOI 10.1016/j.neuro.2016.03.005, PubMed 26994581
35. Dahlberg D, Ivanovic J, Hassel B (2015)
    Toxic levels of ammonia in human brain abscess
    J Neurosurg, 124 (3), 854-60
    DOI 10.3171/2015.1.JNS142582, PubMed 26274996
36. Solyga VM, Western E, Solheim H, Hassel B, Kerty E (2015)
    [Posterior cortical atrophy]
    Tidsskr Nor Laegeforen, 135 (10), 949-52
    DOI 10.4045/tidsskr.14.1127, PubMed 26037756
37. Dahlberg D, Mariussen E, Goverud IL, Tønjum T, Mæhlen J, Antal EA, Hassel B (2015)
    Staphylococcal α-hemolysin is neurotoxic and causes lysis of brain cells in vivo and in vitro
    Neurotoxicology, 48, 61-7
    DOI 10.1016/j.neuro.2015.03.001, PubMed 25757835
38. Hassel B, Elsais A, Frøland AS, Taubøll E, Gjerstad L, Quan Y, Dingledine R, Rise F (2015)
    Uptake and metabolism of fructose by rat neocortical cells in vivo and by isolated nerve terminals in vitro
    J Neurochem, 133 (4), 572-81
    DOI 10.1111/jnc.13079, PubMed 25708447
39. Dahlberg D, Ivanovic J, Mariussen E, Hassel B (2015)
    High extracellular levels of potassium and trace metals in human brain abscess
    Neurochem Int, 82, 28-32
    DOI 10.1016/j.neuint.2015.02.003, PubMed 25684071
40. Hassel B, Dahlberg D, Mariussen E, Goverud IL, Antal EA, Tønjum T, Maehlen J (2014)
    Brain infection with Staphylococcus aureus leads to high extracellular levels of glutamate, aspartate, γ-aminobutyric acid, and zinc
    J Neurosci Res, 92 (12), 1792-800
    DOI 10.1002/jnr.23444, PubMed 25043715
41. Dahlberg D, Ivanovic J, Hassel B (2014)
    High extracellular concentration of excitatory amino acids glutamate and aspartate in human brain abscess
    Neurochem Int, 69, 41-7
    DOI 10.1016/j.neuint.2014.03.001, PubMed 24632003
42. Hassel B (2012)
    [A description of early hydrocephalus with macrocephaly, cerebral palsy, epilepsy, intellectual disability, and growth retardation by Norwegian novelist Amalie Skram (1846-1905)]
    Tidsskr Nor Laegeforen, 132 (23-24), 2632-5
    DOI 10.4045/tidsskr.12.0912, PubMed 23338097
43. Hassel B (2013)
    Tetanus: pathophysiology, treatment, and the possibility of using botulinum toxin against tetanus-induced rigidity and spasms
    Toxins (Basel), 5 (1), 73-83
    DOI 10.3390/toxins5010073, PubMed 23299659
44. Zhou Y, Holmseth S, Guo C, Hassel B, Höfner G, Huitfeldt HS, Wanner KT, Danbolt NC (2012)
    Deletion of the γ-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents
    J Biol Chem, 287 (42), 35733-35746
    DOI 10.1074/jbc.M112.368175, PubMed 22896705
45. Hassel B, Taubøll E, Shaw R, Gjerstad L, Dingledine R (2010)
    Region-specific changes in gene expression in rat brain after chronic treatment with levetiracetam or phenytoin
    Epilepsia, 51 (9), 1714-20
    DOI 10.1111/j.1528-1167.2010.02545.x, PubMed 20345932
46. Hassel B, Solyga V, Lossius A (2008)
    High-affinity choline uptake and acetylcholine-metabolizing enzymes in CNS white matter. A quantitative study
    Neurochem Int, 53 (6-8), 193-8
    DOI 10.1016/j.neuint.2008.06.008, PubMed 18674580
47. Herrman H, Braekhus A, Aaserud O, Aukrust P, Stubhaug A, Hassel B (2008)
    Early treatment of tetanus-induced trismus with botulinum toxin A
    Anesth Analg, 106 (5), 1591
    DOI 10.1213/ANE.0b013e31816a30f0, PubMed 18420892
48. Hassel B, Tessler S, Faull RL, Emson PC (2007)
    Glutamate uptake is reduced in prefrontal cortex in Huntington's disease
    Neurochem Res, 33 (2), 232-7
    DOI 10.1007/s11064-007-9463-1, PubMed 17726644
49. Bough KJ, Paquet M, Paré JF, Hassel B, Smith Y, Hall RA, Dingledine R (2007)
    Evidence against enhanced glutamate transport in the anticonvulsant mechanism of the ketogenic diet
    Epilepsy Res, 74 (2-3), 232-6
    DOI 10.1016/j.eplepsyres.2007.03.002, PubMed 17416486
50. Henjum S, Hassel B (2007)
    High-affinity glycine and glutamate transport in pig forebrain white and gray matter: a quantitative study
    Neurochem Int, 50 (5), 696-702
    DOI 10.1016/j.neuint.2007.01.002, PubMed 17316904
51. Morland C, Henjum S, Iversen EG, Skrede KK, Hassel B (2007)
    Evidence for a higher glycolytic than oxidative metabolic activity in white matter of rat brain
    Neurochem Int, 50 (5), 703-9
    DOI 10.1016/j.neuint.2007.01.003, PubMed 17316901
52. Nguyen NH, Morland C, Gonzalez SV, Rise F, Storm-Mathisen J, Gundersen V, Hassel B (2007)
    Propionate increases neuronal histone acetylation, but is metabolized oxidatively by glia. Relevance for propionic acidemia
    J Neurochem, 101 (3), 806-14
    DOI 10.1111/j.1471-4159.2006.04397.x, PubMed 17286595
53. Nguyen NH, Gonzalez SV, Hassel B (2007)
    Formation of glycerol from glucose in rat brain and cultured brain cells. Augmentation with kainate or ischemia
    J Neurochem, 101 (6), 1694-700
    DOI 10.1111/j.1471-4159.2006.04433.x, PubMed 17286586
54. Nguyen N, Gonzalez SV, Rise F, Hassel B (2006)
    Cerebral metabolism of glucose and pyruvate in soman poisoning. A 13C nuclear magnetic resonance spectroscopic study
    Neurotoxicology, 28 (1), 13-8
    DOI 10.1016/j.neuro.2006.09.007, PubMed 17087995
55. Henjum S, Hassel B (2006)
    High-affinity GABA uptake and GABA-metabolizing enzymes in pig forebrain white matter: a quantitative study
    Neurochem Int, 50 (2), 365-70
    DOI 10.1016/j.neuint.2006.09.004, PubMed 17069932
56. Bough KJ, Wetherington J, Hassel B, Pare JF, Gawryluk JW, Greene JG, Shaw R, Smith Y, Geiger JD, Dingledine RJ (2006)
    Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet
    Ann Neurol, 60 (2), 223-35
    DOI 10.1002/ana.20899, PubMed 16807920
57. Hassel B (2006)
    Nicotinic mechanisms contribute to soman-induced symptoms and lethality
    Neurotoxicology, 27 (4), 501-7
    DOI 10.1016/j.neuro.2006.01.007, PubMed 16500708
58. Gonzalez SV, Nguyen NH, Rise F, Hassel B (2005)
    Brain metabolism of exogenous pyruvate
    J Neurochem, 95 (1), 284-93
    DOI 10.1111/j.1471-4159.2005.03365.x, PubMed 16181432
59. Morland C, Boldingh KA, Iversen EG, Hassel B (2004)
    Valproate is neuroprotective against malonate toxicity in rat striatum: an association with augmentation of high-affinity glutamate uptake
    J Cereb Blood Flow Metab, 24 (11), 1226-34
    DOI 10.1097/01.WCB.0000138666.25305.A7, PubMed 15545916
60. Hassel B, Boldingh KA, Narvesen C, Iversen EG, Skrede KK (2003)
    Glutamate transport, glutamine synthetase and phosphate-activated glutaminase in rat CNS white matter. A quantitative study
    J Neurochem, 87 (1), 230-7
    DOI 10.1046/j.1471-4159.2003.01984.x, PubMed 12969269
61. Nguyen NH, Bråthe A, Hassel B (2003)
    Neuronal uptake and metabolism of glycerol and the neuronal expression of mitochondrial glycerol-3-phosphate dehydrogenase
    J Neurochem, 85 (4), 831-42
    DOI 10.1046/j.1471-4159.2003.01762.x, PubMed 12716415
62. Hassel B, Bråthe A, Petersen D (2002)
    Cerebral dicarboxylate transport and metabolism studied with isotopically labelled fumarate, malate and malonate
    J Neurochem, 82 (2), 410-9
    DOI 10.1046/j.1471-4159.2002.00986.x, PubMed 12124442
63. Hassel B, Sonnewald U (2002)
    Effects of potassium and glutamine on metabolism of glucose in astrocytes
    Neurochem Res, 27 (1-2), 167-71
    DOI 10.1023/a:1014827327690, PubMed 11926271