Publications Experimental Drug Abuse Research
Publications 2024
Metabolite markers for three synthetic tryptamines N-ethyl-N-propyltryptamine, 4-hydroxy-N-ethyl-N-propyltryptamine, and 5-methoxy-N-ethyl-N-propyltryptamine
Drug Test Anal (in press)
DOI 10.1002/dta.3668, PubMed 38459837
Role of aquaporin-4 polarization in extracellular solute clearance
Fluids Barriers CNS, 21 (1), 28
DOI 10.1186/s12987-024-00527-7, PubMed 38532513
Driving under the influence of cocaine and MDMA: Relationship between blood concentrations and results from clinical test of impairment
J Anal Toxicol, 48 (5), 380-387
DOI 10.1093/jat/bkae024, PubMed 38613441
[Not Available]
Tidsskr Nor Laegeforen, 144 (8)
DOI 10.4045/tidsskr.24.0160, PubMed 38934312
Effects of prenatal exposure to methadone or buprenorphine and maternal separation on anxiety-like behavior in rats
Drug Alcohol Depend, 262, 111367
DOI 10.1016/j.drugalcdep.2024.111367, PubMed 39003831
Electromembrane extraction of drugs of abuse and prescription drugs from micropulverized hair
J Anal Toxicol, 48 (7), 489-498
DOI 10.1093/jat/bkae051, PubMed 38905017
Publications 2023
Heroin metabolism in human blood and its impact for the design of an immunotherapeutic approach against heroin effects
Basic Clin Pharmacol Toxicol, 133 (4), 418-427
DOI 10.1111/bcpt.13926, PubMed 37452619
Crash-involved THC-positive drivers in Norway have a high frequency of polysubstance use
Drug Alcohol Depend, 244, 109800
DOI 10.1016/j.drugalcdep.2023.109800, PubMed 36774807
Pharmacokinetics and pharmacodynamics of cannabis-based medicine in a patient population included in a randomized, placebo-controlled, clinical trial
Clin Transl Sci, 17 (1), e13685
DOI 10.1111/cts.13685, PubMed 38054364
Scalable production of tissue-like vascularized liver organoids from human PSCs
Exp Mol Med, 55 (9), 2005-2024
DOI 10.1038/s12276-023-01074-1, PubMed 37653039
Distribution of morphine and methadone to the brain in a developmental chicken embryo model
Toxicol Appl Pharmacol, 479, 116731
DOI 10.1016/j.taap.2023.116731, PubMed 37866706
High-throughput quantification of emerging "nitazene" benzimidazole opioid analogs by microextraction and UHPLC-MS-MS
J Anal Toxicol, 47 (9), 787-796
DOI 10.1093/jat/bkad071, PubMed 37700512
Psychoactive substances and previous hospital admissions, triage and length of stay in rural injuries: a prospective observational study
Scand J Trauma Resusc Emerg Med, 31 (1), 86
DOI 10.1186/s13049-023-01156-z, PubMed 38012704
Comparative Study of Postmortem Concentrations of Benzodiazepines and Z-Hypnotics in Several Different Matrices
J Anal Toxicol, 47 (3), 287-298
DOI 10.1093/jat/bkac106, PubMed 36542823
Publications 2022
Increased heroin intake and relapse vulnerability in intermittent relative to continuous self-administration: Sex differences in rats
Br J Pharmacol, 180 (7), 910-926
DOI 10.1111/bph.15791, PubMed 34986504
Concentrations of psychoactive substances in blood samples from non-fatal and fatal opioid overdoses
Br J Clin Pharmacol, 88 (10), 4494-4504
DOI 10.1111/bcp.15365, PubMed 35470456
Methadone, Buprenorphine, Oxycodone, Fentanyl and Tramadol in Multiple Postmortem Matrices
J Anal Toxicol, 46 (6), 600-610
DOI 10.1093/jat/bkab071, PubMed 34115841
[High level of ferritin and HDL cholesterol is associated with high alcohol consumption]
Tidsskr Nor Laegeforen, 142 (17)
DOI 10.4045/tidsskr.22.0431, PubMed 36416649
Deaths associated with MDMA in the period 2000-2019
Tidsskr Nor Laegeforen, 142 (8)
DOI 10.4045/tidsskr.21.0547, PubMed 35635429
"Organ-in-a-Column" Coupled On-line with Liquid Chromatography-Mass Spectrometry
Anal Chem, 94 (50), 17677-17684
DOI 10.1021/acs.analchem.2c04530, PubMed 36484723
Systematic screening of substance use upon hospitalisation
Tidsskr Nor Laegeforen, 142 (14)
DOI 10.4045/tidsskr.22.0481, PubMed 36226432
[Yew – a toxic shrub veiled in myth with medical potential]
Tidsskr Nor Laegeforen, 142 (6)
DOI 10.4045/tidsskr.22.0033, PubMed 35383451
The Combined Effects of Amyloidosis and Serotonin Deficiency by Tryptophan Hydroxylase-2 Knockout Impacts Viability of the APP/PS1 Mouse Model of Alzheimer's Disease
J Alzheimers Dis, 85 (3), 1283-1300
DOI 10.3233/JAD-210581, PubMed 34924373
Publications 2021
Does the preparation for intravenous administration affect the composition of heroin injections? A controlled laboratory study
Addiction, 116 (11), 3104-3112
DOI 10.1111/add.15492, PubMed 33739552
Pharmacokinetics and pharmacodynamics of cyclopropylfentanyl in male rats
Psychopharmacology (Berl), 238 (12), 3629-3641
DOI 10.1007/s00213-021-05981-x, PubMed 34613431
Discovering the major metabolites of the three novel fentanyl analogues 3-methylcrotonylfentanyl, furanylbenzylfentanyl, and 4-fluorocyclopropylbenzylfentanyl for forensic case work
Forensic Toxicol., 39 (1), 167-178
DOI 10.1007/s11419-020-00560-9
[Is the conclusion reliable?]
Tidsskr Nor Laegeforen, 141 (7)
DOI 10.4045/tidsskr.21.0306, PubMed 33950652
Which illicit drugs are injected in Oslo? A study based on analysis of drug residues in used injection equipment and self-reported information
Scand J Public Health, 51 (1), 21-27
DOI 10.1177/14034948211043984, PubMed 34538164
The alcohol marker phosphatidylethanol is closely related to AST, GGT, ferritin and HDL-C
Basic Clin Pharmacol Toxicol, 130 (1), 182-190
DOI 10.1111/bcpt.13662, PubMed 34591374
The Association between the Alcohol Biomarker Phosphatidylethanol (PEth) and Self-Reported Alcohol Consumption among Russian and Norwegian Medical Patients
Alcohol Alcohol, 56 (6), 726-736
DOI 10.1093/alcalc/agab013, PubMed 33677484
Multimorbidity, psychoactive substance use and psychological distress among acute medically ill patients: a cross-sectional study
BMJ Open, 11 (11), e052428
DOI 10.1136/bmjopen-2021-052428, PubMed 34815283
Tumor Necrosis Factor (TNF) Is Required for Spatial Learning and Memory in Male Mice under Physiological, but Not Immune-Challenged Conditions
Cells, 10 (3)
DOI 10.3390/cells10030608, PubMed 33803476
Distribution of tetrahydrocannabinol and cannabidiol in several different postmortem matrices
Forensic Sci Int, 329, 111082
DOI 10.1016/j.forsciint.2021.111082, PubMed 34775328
Electromembrane Extraction and Mass Spectrometry for Liver Organoid Drug Metabolism Studies
Anal Chem, 93 (7), 3576-3585
DOI 10.1021/acs.analchem.0c05082, PubMed 33534551
Comparative Neuropharmacology and Pharmacokinetics of Methamphetamine and Its Thiophene Analog Methiopropamine in Rodents
Int J Mol Sci, 22 (21)
DOI 10.3390/ijms222112002, PubMed 34769427
Psychoactive substances have major impact on injuries in rural arctic Norway - A prospective observational study
Acta Anaesthesiol Scand, 65 (6), 824-833
DOI 10.1111/aas.13807, PubMed 33638866
Peripherally administered persistent organic pollutants distribute to the brain of developing chicken embryo in concentrations relevant for human exposure
Neurotoxicology, 88, 79-87
DOI 10.1016/j.neuro.2021.10.013, PubMed 34757084
Chicken embryo as animal model to study drug distribution to the developing brain
J Pharmacol Toxicol Methods, 112, 107105
DOI 10.1016/j.vascn.2021.107105, PubMed 34284116
Publications 2020
Prenatal exposure to methadone or buprenorphine and long-term outcomes: A meta-analysis
Early Hum Dev, 143, 104997
DOI 10.1016/j.earlhumdev.2020.104997, PubMed 32146140
CaMKII is activated in opioid induced conditioned place preference, but αCaMKII Thr286 autophosphorylation is not necessary for its establishment
Behav Brain Res, 390, 112676
DOI 10.1016/j.bbr.2020.112676, PubMed 32407818
Post-mortem toxicological analyses of blood samples from 107 patients receiving opioid agonist treatment: substances detected and pooled opioid and benzodiazepine concentrations
Addiction, 116 (4), 845-855
DOI 10.1111/add.15211, PubMed 32738014
Selectivity and sensitivity of urine fentanyl test strips to detect fentanyl analogues in illicit drugs
Int J Drug Policy, 90, 103065
DOI 10.1016/j.drugpo.2020.103065, PubMed 33333419
Prevalence of psychoactive substance use among acutely hospitalised patients in Oslo and Moscow: a cross-sectional, observational study
BMJ Open, 10 (9), e032572
DOI 10.1136/bmjopen-2019-032572, PubMed 32948540
Determination of drug residues in used syringe needles
Drug Test Anal, 12 (3), 410-416
DOI 10.1002/dta.2759, PubMed 31899604
Blood Concentrations of Designer Benzodiazepines: Relation to Impairment and Findings in Forensic Cases
J Anal Toxicol, 44 (8), 905-914
DOI 10.1093/jat/bkaa043, PubMed 32369173
Associations between psychoactive substance use and sensation seeking behavior among drivers in Norway
BMC Public Health, 20 (1), 23
DOI 10.1186/s12889-019-8087-0, PubMed 31914964
Corrigendum to "Harmful alcohol use among acutely ill hospitalized medical patients in Oslo and Moscow: A cross-sectional study" [Drug Alcohol Depend. 204 (2019) 107588]
Drug Alcohol Depend, 213, 108073
DOI 10.1016/j.drugalcdep.2020.108073, PubMed 32570137
Prenatal exposure to methadone or buprenorphine alters µ-opioid receptor binding and downstream signaling in the rat brain
Int J Dev Neurosci, 80 (5), 443-453
DOI 10.1002/jdn.10043, PubMed 32484968
Prenatal exposure to methadone or buprenorphine impairs cognitive performance in young adult rats
Drug Alcohol Depend, 212, 108008
DOI 10.1016/j.drugalcdep.2020.108008, PubMed 32402939
Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly
Brain Res Bull, 161, 13-20
DOI 10.1016/j.brainresbull.2020.05.001, PubMed 32418901
Comparison of anticoagulant rodenticide concentrations in liver and feces from apparently healthy red foxes
J Vet Diagn Invest, 32 (4), 560-564
DOI 10.1177/1040638720927365, PubMed 32476615
Determination of anticoagulant rodenticides in faeces of exposed dogs and in a healthy dog population
Acta Vet Scand, 62 (1), 30
DOI 10.1186/s13028-020-00531-5, PubMed 32546243
Comparison of the Diagnostic Value of Phosphatidylethanol and Carbohydrate-Deficient Transferrin as Biomarkers of Alcohol Consumption
Alcohol Clin Exp Res, 45 (1), 153-162
DOI 10.1111/acer.14503, PubMed 33164220
Publications 2019
Evidence for nonlinear accumulation of the ultrapotent fentanyl analog, carfentanil, after systemic administration to male rats
Neuropharmacology, 158, 107596
DOI 10.1016/j.neuropharm.2019.04.002, PubMed 30965021
Distinguishing Between Cyclopropylfentanyl and Crotonylfentanyl by Methods Commonly Available in the Forensic Laboratory
Ther Drug Monit, 41 (4), 519-527
DOI 10.1097/FTD.0000000000000617, PubMed 30807539
[Medical cannabis]
Tidsskr Nor Laegeforen, 139 (15)
DOI 10.4045/tidsskr.19.0595, PubMed 31642634
Medical cannabis
Tidsskr. Nor. Laegeforen., 139 (15), 1437
Opioid receptor-mediated changes in the NMDA receptor in developing rat and chicken
Int J Dev Neurosci, 78, 19-27
DOI 10.1016/j.ijdevneu.2019.07.009, PubMed 31351113
Harmful alcohol use among acutely ill hospitalized medical patients in Oslo and Moscow: A cross-sectional study
Drug Alcohol Depend, 204, 107588
DOI 10.1016/j.drugalcdep.2019.107588, PubMed 31590131
High Accumulation of Methadone Compared with Buprenorphine in Fetal Rat Brain after Maternal Exposure
J Pharmacol Exp Ther, 371 (1), 130-137
DOI 10.1124/jpet.119.259531, PubMed 31358559
The role of 6-acetylmorphine in heroin-induced reward and locomotor sensitization in mice
Addict Biol, 25 (2), e12727
DOI 10.1111/adb.12727, PubMed 30788879
Interpreting oral fluid drug results in prisoners: monitoring current drug intake and detection times for drugs self-administered prior to detention
Forensic Toxicol., 37 (1), 59-74
DOI 10.1007/s11419-018-0434-9
PREVALENCE OF ANTICOAGULANT RODENTICIDES IN FECES OF WILD RED FOXES (VULPES VULPES) IN NORWAY
J Wildl Dis, 55 (4), 834-843
DOI 10.7589/2019-01-027, PubMed 31112468
Pharmacokinetics of Single Doses of Methadone and Buprenorphine in Blood and Oral Fluid in Healthy Volunteers and Correlation With Effects on Psychomotor and Cognitive Functions
J Clin Psychopharmacol, 39 (5), 489-493
DOI 10.1097/JCP.0000000000001077, PubMed 31305338
Fatally injured drivers in Norway 2005-2015-Trends in substance use and crash characteristics
Traffic Inj Prev, 20 (5), 460-466
DOI 10.1080/15389588.2019.1616700, PubMed 31169405
Driver-related risk factors of fatal road traffic crashes associated with alcohol or drug impairment
Accid Anal Prev, 131, 191-199
DOI 10.1016/j.aap.2019.06.014, PubMed 31306833
Publications 2018
The active heroin metabolite 6-acetylmorphine has robust reinforcing effects as assessed by self-administration in the rat
Neuropharmacology, 150, 192-199
DOI 10.1016/j.neuropharm.2018.12.023, PubMed 30578794
Addressing the Fentanyl Analogue Epidemic by Multiplex UHPLC-MS/MS Analysis of Whole Blood
Ther Drug Monit, 40 (6), 738-748
DOI 10.1097/FTD.0000000000000564, PubMed 30157097
Roadside survey of alcohol and drug use among Norwegian drivers in 2016-2017: A follow-up of the 2008-2009 survey
Traffic Inj Prev, 19 (6), 555-562
DOI 10.1080/15389588.2018.1478087, PubMed 29927625
Is Hair Analysis Useful in Postmortem Cases?
J Anal Toxicol, 42 (1), 49-54
DOI 10.1093/jat/bkx077, PubMed 28977558
Association between speeding and use of alcohol and medicinal and illegal drugs and involvement in road traffic crashes among motor vehicle drivers
Traffic Inj Prev, 19 (8), 779-785
DOI 10.1080/15389588.2018.1518577, PubMed 30681887
A Monoclonal Antibody against 6-Acetylmorphine Protects Female Mice Offspring from Adverse Behavioral Effects Induced by Prenatal Heroin Exposure
J Pharmacol Exp Ther, 368 (1), 106-115
DOI 10.1124/jpet.118.251504, PubMed 30361238
Morphine reduced perceived anger from neutral and implicit emotional expressions
Psychoneuroendocrinology, 91, 123-131
DOI 10.1016/j.psyneuen.2018.02.035, PubMed 29550675
Postmortem analysis of three methoxyacetylfentanyl-related deaths in Denmark and in vitro metabolite profiling in pooled human hepatocytes
Forensic Sci Int, 290, 310-317
DOI 10.1016/j.forsciint.2018.07.020, PubMed 30107329
Separation of isomers of new psychoactive substances and isotope-labeled amphetamines using UHPSFC-MS/MS and UHPLC-MS/MS
J. Liq. Chromatogr. Relat. Technol., 41 (7), 391-400
DOI 10.1080/10826076.2017.1388818
Quantitative method for analysis of six anticoagulant rodenticides in faeces, applied in a case with repeated samples from a dog
Acta Vet Scand, 60 (1), 3
DOI 10.1186/s13028-018-0357-9, PubMed 29343296
A clinical trial on the acute effects of methadone and buprenorphine on actual driving and cognitive function of healthy volunteers
Br J Clin Pharmacol, 85 (2), 442-453
DOI 10.1111/bcp.13818, PubMed 30515857
Determination of cocaine, metabolites and a crack cocaine biomarker in whole blood by liquid-liquid extraction and UHPLC-MS/MS
Forensic Sci Int, 289, 165-174
DOI 10.1016/j.forsciint.2018.05.030, PubMed 29885489
Can measurements of heroin metabolites in post-mortem matrices other than peripheral blood indicate if death was rapid or delayed?
Forensic Sci Int, 290, 121-128
DOI 10.1016/j.forsciint.2018.06.041, PubMed 30015276
Metabolites of Heroin in Several Different Post-mortem Matrices
J Anal Toxicol, 42 (5), 311-320
DOI 10.1093/jat/bky002, PubMed 29409037
Rapid determination of designer benzodiazepines, benzodiazepines, and Z-hypnotics in whole blood using parallel artificial liquid membrane extraction and UHPLC-MS/MS
Anal Bioanal Chem, 410 (20), 4967-4978
DOI 10.1007/s00216-018-1147-y, PubMed 29947895
Comparative Study of Postmortem Concentrations of Antidepressants in Several Different Matrices
J Anal Toxicol, 42 (7), 446-458
DOI 10.1093/jat/bky030, PubMed 29762694
Publications 2017
Determination of adrenaline, noradrenaline and corticosterone in rodent blood by ion pair reversed phase UHPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 1072, 161-172
DOI 10.1016/j.jchromb.2017.11.016, PubMed 29175696
The fungal neurotoxin penitrem A induces the production of reactive oxygen species in human neutrophils at submicromolar concentrations
Toxicology, 392, 64-70
DOI 10.1016/j.tox.2017.10.008, PubMed 29037868
Differences in combinations and concentrations of drugs of abuse in fatal intoxication and driving under the influence cases
Forensic Sci Int, 281, 127-133
DOI 10.1016/j.forsciint.2017.10.045, PubMed 29128652
Corrigendum to "Differences in combinations and concentrations of drugs of abuse in fatal intoxication and driving under the influence cases" [Forensic Sci. Int. 281 (2017) 127-133]
Forensic Sci Int, 283, 219
DOI 10.1016/j.forsciint.2017.12.040, PubMed 29324351
THC and CBD in blood samples and seizures in Norway: Does CBD affect THC-induced impairment in apprehended subjects?
Forensic Sci Int, 276, 12-17
DOI 10.1016/j.forsciint.2017.04.006, PubMed 28463706
Zopiclone concentrations in oral fluid and blood after, administration of therapeutic doses of zopiclone
Forensic Sci Int, 278, 177-183
DOI 10.1016/j.forsciint.2017.07.004, PubMed 28735217
Restoration of Cognitive Performance in Mice Carrying a Deficient Allele of 8-Oxoguanine DNA Glycosylase by X-ray Irradiation
Neurotox Res, 33 (4), 824-836
DOI 10.1007/s12640-017-9833-7, PubMed 29101721
Conversion factors for assessment of driving impairment after exposure to multiple benzodiazepines/z-hypnotics or opioids
Forensic Sci Int, 281, 29-36
DOI 10.1016/j.forsciint.2017.10.022, PubMed 29101905
Increasing use of cannabis among arrested drivers in Norway
Traffic Inj Prev, 18 (8), 801-806
DOI 10.1080/15389588.2017.1321114, PubMed 28448164
Toxicological findings in suspected drug-impaired drivers in Norway - Trends during 1990-2015
Forensic Sci Int, 280, 15-24
DOI 10.1016/j.forsciint.2017.09.010, PubMed 28942374
Studies on Para-Methoxymethamphetamine (PMMA) Metabolite Pattern and Influence of CYP2D6 Genetics in Human Liver Microsomes and Authentic Samples from Fatal PMMA Intoxications
Drug Metab Dispos, 45 (12), 1326-1335
DOI 10.1124/dmd.117.077263, PubMed 28978661
Publications 2016
Extended Detection of Amphetamine and Methamphetamine in Oral Fluid
Ther Drug Monit, 38 (1), 114-9
DOI 10.1097/FTD.0000000000000248, PubMed 26402425
Validated methods for determination of neurotransmitters and metabolites in rodent brain tissue and extracellular fluid by reversed phase UHPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 1028, 120-129
DOI 10.1016/j.jchromb.2016.06.011, PubMed 27336704
Low-Chlorinated Non-Dioxin-like Polychlorinated Biphenyls Present in Blood and Breast Milk Induce Higher Levels of Reactive Oxygen Species in Neutrophil Granulocytes than High-Chlorinated Congeners
Basic Clin Pharmacol Toxicol, 119 (6), 588-597
DOI 10.1111/bcpt.12620, PubMed 27194217
Comparison of (+)- and (-)-Naloxone on the Acute Psychomotor-Stimulating Effects of Heroin, 6-Acetylmorphine, and Morphine in Mice
J Pharmacol Exp Ther, 358 (2), 209-15
DOI 10.1124/jpet.116.233544, PubMed 27278234
Impairment due to alcohol, tetrahydrocannabinol, and benzodiazepines in impaired drivers compared to experimental studies
Traffic Inj Prev, 18 (3), 244-250
DOI 10.1080/15389588.2016.1201205, PubMed 27327554
New psychoactive substances
Tidsskr. Nor. Laegeforen., 136 (8), 714-717
Novel psychoactive substances
Tidsskr Nor Laegeforen, 136 (8), 714-7
DOI 10.4045/tidsskr.15.1278, PubMed 27143461
Pharmacological Effects of a Monoclonal Antibody against 6-Monoacetylmorphine upon Heroin-Induced Locomotor Activity and Pharmacokinetics in Mice
J Pharmacol Exp Ther, 358 (2), 181-9
DOI 10.1124/jpet.116.233510, PubMed 27217591
[Revision of fixed limits for drugs in the traffic]
Tidsskr Nor Laegeforen, 136 (19), 1619-1620
DOI 10.4045/tidsskr.16.0730, PubMed 27790887
New drugs right from the online
Tidsskr. Nor. Laegeforen., 136 (8), 721-723
New designer drugs from the web
Tidsskr Nor Laegeforen, 136 (8), 721-3
DOI 10.4045/tidsskr.15.1276, PubMed 27143463
Determination of 21 drugs in oral fluid using fully automated supported liquid extraction and UHPLC-MS/MS
Drug Test Anal, 9 (5), 808-823
DOI 10.1002/dta.2045, PubMed 27464485
Is toxicity of PMMA (paramethoxymethamphetamine) associated with cytochrome P450 pharmacogenetics?
Forensic Sci Int, 261, 137-47
DOI 10.1016/j.forsciint.2016.02.027, PubMed 26930544
[Does stronger cannabis cause more health problems?]
Tidsskr Nor Laegeforen, 136 (20), 1736-1738
DOI 10.4045/tidsskr.15.1297, PubMed 27830910
Detection of Nitrobenzodiazepines and Their 7-Amino Metabolites in Oral Fluid
J Anal Toxicol, 40 (4), 310-2
DOI 10.1093/jat/bkw020, PubMed 27013620
Oral fluid drug analysis in the age of new psychoactive substances
Bioanalysis, 8 (7), 691-710
DOI 10.4155/bio-2015-0027, PubMed 26964619
Publications 2015
[Prevalence of injuries associated with the «russ» celebration in Norway]
Tidsskr Nor Laegeforen, 135 (7), 648-52
DOI 10.4045/tidsskr.14.0238, PubMed 25899369
Associations between driving under the influence of alcohol or drugs, speeding and seatbelt use among fatally injured car drivers in Norway
Accid Anal Prev, 78, 14-19
DOI 10.1016/j.aap.2014.12.025, PubMed 25725424
Determination of dopamine concentrations in brain extracellular fluid using microdialysis with short sampling intervals, analyzed by ultra high performance liquid chromatography tandem mass spectrometry
J Pharmacol Toxicol Methods, 74, 75-9
DOI 10.1016/j.vascn.2015.06.002, PubMed 26123500
A fatal intoxication with phenazone (antipyrine)
Forensic Sci Int, 248, e13-5
DOI 10.1016/j.forsciint.2015.01.001, PubMed 25631541
Determination of safety margins for whole blood concentrations of alcohol and nineteen drugs in driving under the influence cases
Forensic Sci Int, 259, 119-26
DOI 10.1016/j.forsciint.2015.12.009, PubMed 26773222
Detection Times of Diazepam, Clonazepam, and Alprazolam in Oral Fluid Collected From Patients Admitted to Detoxification, After High and Repeated Drug Intake
Ther Drug Monit, 37 (4), 451-60
DOI 10.1097/FTD.0000000000000174, PubMed 25549207
Fatal poisoning in drug addicts in the Nordic countries in 2012
Forensic Sci Int, 248, 172-80
DOI 10.1016/j.forsciint.2015.01.003, PubMed 25645132
Methiopropamine in blood samples from drivers suspected of being under the influence of drugs
Traffic Inj Prev, 17 (1), 1-4
DOI 10.1080/15389588.2015.1036157, PubMed 25874580
Publications 2014
Detection time for THC in oral fluid after frequent cannabis smoking
Ther Drug Monit, 36 (6), 808-14
DOI 10.1097/FTD.0000000000000092, PubMed 24819969
Evaluation of ¹³C- and ²H-labeled internal standards for the determination of amphetamines in biological samples, by reversed-phase ultra-high performance liquid chromatography-tandem mass spectrometry
J Chromatogr A, 1344, 83-90
DOI 10.1016/j.chroma.2014.04.020, PubMed 24780257
A monoclonal antibody specific for 6-monoacetylmorphine reduces acute heroin effects in mice
J Pharmacol Exp Ther, 349 (3), 568-76
DOI 10.1124/jpet.113.212035, PubMed 24700886
Recent trends in the availability and use of amphetamine and methamphetamine in Norway
Forensic Sci Int, 246, 92-7
DOI 10.1016/j.forsciint.2014.11.010, PubMed 25485948
Effects of long-term exposure of 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy") on neuronal transmitter transport, brain immuno-regulatory systems and progression of experimental periodontitis in rats
Neurochem Int, 72, 30-6
DOI 10.1016/j.neuint.2014.04.002, PubMed 24726767
3-Methoxynaltrexone is not a selective antagonist for the acute psychomotor stimulating effects of heroin and 6-monoacetylmorphine in mice
Pharmacol Biochem Behav, 122, 82-8
DOI 10.1016/j.pbb.2014.03.018, PubMed 24699386
Role of 6-monoacetylmorphine in the acute release of striatal dopamine induced by intravenous heroin
Int J Neuropsychopharmacol, 17 (9), 1357-65
DOI 10.1017/S1461145714000169, PubMed 24576415
Long-term stability of morphine, codeine, and 6-acetylmorphine in real-life whole blood samples, stored at -20°C
Forensic Sci Int, 239, 6-10
DOI 10.1016/j.forsciint.2014.03.008, PubMed 24709028
An accidental poisoning with mitragynine
Forensic Sci Int, 245, e29-32
DOI 10.1016/j.forsciint.2014.10.025, PubMed 25453780
Lethal poisonings with AH-7921 in combination with other substances
Forensic Sci Int, 244, e21-4
DOI 10.1016/j.forsciint.2014.08.013, PubMed 25216892
Concentrations of APINACA, 5F-APINACA, UR-144 and its degradant product in blood samples from six impaired drivers compared to previous reported concentrations of other synthetic cannabinoids
Forensic Sci Int, 246, 98-103
DOI 10.1016/j.forsciint.2014.11.012, PubMed 25485949
Determination of a selection of anti-epileptic drugs and two active metabolites in whole blood by reversed phase UPLC-MS/MS and some examples of application of the method in forensic toxicology cases
Drug Test Anal, 7 (7), 634-44
DOI 10.1002/dta.1733, PubMed 25331692
Pharmacokinetic interactions between ethanol and heroin: a study on post-mortem cases
Forensic Sci Int, 242, 127-134
DOI 10.1016/j.forsciint.2014.06.032, PubMed 25050840
Toxicological profile of ultrapure 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in adult rats
PLoS One, 9 (8), e104639
DOI 10.1371/journal.pone.0104639, PubMed 25137063
Drugged driving arrests in Norway before and after the implementation of per se law
Forensic Sci Int, 245, 171-7
DOI 10.1016/j.forsciint.2014.10.038, PubMed 25447190
Very long Detection Times after High and repeated intake of Heroin and Methadone, measured in Oral Fluid
Scand. J. Forensic Sci., 20 (2), 34-41
DOI 10.2478/sjfs-2014-0004
Very long Detection Times after High and repeated intake of Heroin and Methadone, measured in Oral Fluid
Scandinavian Journal of Forensic Science, 20 (2), 34-41
DOI 10.2478/sjfs-2014-0004, PublikaID 292
Publications 2013
Quantitative determination of fifteen basic pharmaceuticals in ante- and post-mortem whole blood by high pH mobile phase reversed phase ultra high performance liquid chromatography-tandem mass spectrometry
J Chromatogr B Analyt Technol Biomed Life Sci, 927, 112-23
DOI 10.1016/j.jchromb.2012.12.039, PubMed 23380540
The interference of ethanol with heroin-stimulated psychomotor activation in mice is not related to changed brain concentrations of the active metabolites 6MAM or morphine
Basic Clin Pharmacol Toxicol, 114 (2), 197-201
DOI 10.1111/bcpt.12133, PubMed 24102968
Codeine to morphine concentration ratios in samples from living subjects and autopsy cases after incubation
J Anal Toxicol, 38 (2), 99-105
DOI 10.1093/jat/bkt099, PubMed 24324229
Mechanisms of penitrem-induced cerebellar granule neuron death in vitro: possible involvement of GABAA receptors and oxidative processes
Neurotoxicology, 35, 129-36
DOI 10.1016/j.neuro.2013.01.004, PubMed 23313729
Levels of heroin and its metabolites in blood and brain extracellular fluid after i.v. heroin administration to freely moving rats
Br J Pharmacol, 170 (3), 546-56
DOI 10.1111/bph.12305, PubMed 23865556
Less glucuronidation of morphine in the presence of ethanol in vivo
Eur J Clin Pharmacol, 69 (9), 1683-7
DOI 10.1007/s00228-013-1533-5, PubMed 23739999
Methyl tert-butyl ether (MTBE) detected in abnormally high concentrations in postmortem blood and urine from two persons found dead inside a car containing a gasoline spill
J Forensic Sci, 58 (5), 1393-1396
DOI 10.1111/1556-4029.12208, PubMed 23879346
Prevalence of synthetic cannabinoids in blood samples from Norwegian drivers suspected of impaired driving during a seven weeks period
Accid Anal Prev, 62, 26-31
DOI 10.1016/j.aap.2013.09.009, PubMed 24129318
Has the intake of THC by cannabis users changed over the last decade? Evidence of increased exposure by analysis of blood THC concentrations in impaired drivers
Forensic Sci Int, 226 (1-3), 197-201
DOI 10.1016/j.forsciint.2013.01.017, PubMed 23415163
Analyses of beverage remains in drug rape cases revealing drug residues--the possibility of contamination from drug concentrated oral fluid or oral cavity contained tablets
J Forensic Sci, 59 (1), 208-10
DOI 10.1111/1556-4029.12270, PubMed 24117495
Publications 2012
Long-term methadone treatment reduces phosphorylation of CaMKII in rat brain
J Pharm Pharmacol, 64 (6), 843-7
DOI 10.1111/j.2042-7158.2012.01469.x, PubMed 22571262
Long-term methadone treatment reduces phosphorylation of CaMKII in rat brain
J Pharm Pharmacol, Jun;64(6), 843-7
DOI 10.1111/j.2042-7158.2012.01469.x, PublikaID 276
Marine Ο-3 polyunsaturated fatty acids induce sex-specific changes in reinforcer-controlled behaviour and neurotransmitter metabolism in a spontaneously hypertensive rat model of ADHD
Behav Brain Funct, 8, 56
DOI 10.1186/1744-9081-8-56, PubMed 23228189
Long-term stability of GHB in post-mortem samples and samples from living persons, stored at -20°C, using fluoride preservatives
Forensic Sci Int, 222 (1-3), 47-51
DOI 10.1016/j.forsciint.2012.04.033, PubMed 22648054
Simultaneous measurement of heroin and its metabolites in brain extracellular fluid by microdialysis and ultra performance liquid chromatography tandem mass spectrometry
J Pharmacol Toxicol Methods, 66 (1), 14-21
DOI 10.1016/j.vascn.2012.04.009, PubMed 22561414
Methadone does not alter key parameters of adult hippocampal neurogenesis in the heroin-naïve rat
Neurosci Lett, 516 (1), 99-104
DOI 10.1016/j.neulet.2012.03.066, PubMed 22487733
Prolonged excretion of 7-aminoclonazepam in urine after repeated ingestion of clonazepam: a case report
Forensic Sci Int, 222 (1-3), e33-5
DOI 10.1016/j.forsciint.2012.06.018, PubMed 22819278
[Effect and occurrence of synthetic cannabinoids]
Tidsskr Nor Laegeforen, 132 (20), 2285-8
DOI 10.4045/tidsskr.12.0471, PubMed 23736196
Detection of drugs of abuse in simultaneously collected oral fluid, urine and blood from Norwegian drug drivers
Forensic Sci Int, 219 (1-3), 165-71
DOI 10.1016/j.forsciint.2012.01.001, PubMed 22284072
Detection of drugs of abuse in simultaneously collected oral fluid, urine and blood from Norwegian drug drivers
Forensic Sci Int, 219 (1-3), 165
PublikaID 265
[Fixed limits for central stimulants in traffic]
Tidsskr Nor Laegeforen, 132 (3), 275-6
DOI 10.4045/tidsskr.11.1284, PubMed 22314734
Synapsins I and II are not required for insulin secretion from mouse pancreatic β-cells
Endocrinology, 153 (5), 2112-9
DOI 10.1210/en.2011-1702, PubMed 22334712
Publications 2011
Long-term methadone treatment impairs novelty preference in rats both when present and absent in brain tissue
Pharmacol Biochem Behav, 98 (3), 412-6
DOI 10.1016/j.pbb.2011.02.017, PubMed 21352846
Glutamatergic neurotransmission in the synapsin I and II double knock-out mouse
Semin Cell Dev Biol, 22 (4), 400-7
DOI 10.1016/j.semcdb.2011.07.004, PubMed 21827868
Pharmacokinetic modeling of subcutaneous heroin and its metabolites in blood and brain of mice
Addict Biol, 18 (1), 1-7
DOI 10.1111/j.1369-1600.2010.00298.x, PubMed 21481103
Drug screening of whole blood by ultra-performance liquid chromatography-tandem mass spectrometry
J Anal Toxicol, 35 (5), 280-93
DOI 10.1093/anatox/35.5.280, PubMed 21619723
Determination of benzodiazepines in ante-mortem and post-mortem whole blood by solid-supported liquid-liquid extraction and UPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 883-884, 177-88
DOI 10.1016/j.jchromb.2011.10.033, PubMed 22119506
Impairment based legislative limits for driving under the influence of non-alcohol drugs in Norway
Forensic Sci Int, 219 (1-3), 1-11
DOI 10.1016/j.forsciint.2011.11.004, PubMed 22118917
Oral fluid is a viable alternative for monitoring drug abuse: detection of drugs in oral fluid by liquid chromatography-tandem mass spectrometry and comparison to the results from urine samples from patients treated with Methadone or Buprenorphine
J Anal Toxicol, 35 (1), 32-9
DOI 10.1093/anatox/35.1.32, PubMed 21219701
Publications 2010
Comparison of zopiclone concentrations in oral fluid sampled with Intercept(®) oral specimen collection device and Statsure Saliva Sampler™ and concentrations in blood
J Anal Toxicol, 34 (9), 590-3
DOI 10.1093/jat/34.9.590, PubMed 21073813
Publications 2009
Increased locomotor activity induced by heroin in mice: pharmacokinetic demonstration of heroin acting as a prodrug for the mediator 6-monoacetylmorphine in vivo
J Pharmacol Exp Ther, 331 (1), 153-61
DOI 10.1124/jpet.109.152462, PubMed 19541908
The importance of synapsin I and II for neurotransmitter levels and vesicular storage in cholinergic, glutamatergic and GABAergic nerve terminals
Neurochem Int, 55 (1-3), 13-21
DOI 10.1016/j.neuint.2009.02.006, PubMed 19428802
Determination of heroin and its main metabolites in small sample volumes of whole blood and brain tissue by reversed-phase liquid chromatography-tandem mass spectrometry
J Anal Toxicol, 33 (7), 345-50
DOI 10.1093/jat/33.7.345, PubMed 19796503
Different effects on dopamine release in nucleus accumbens in mice by the morphine metabolites morphine-6-glucuronide and morphine-3-glucuronide
Basic Clin Pharmacol Toxicol, 105 (5), 357-60
DOI 10.1111/j.1742-7843.2009.00451.x, PubMed 19663818
Interactions between morphine and the morphine-glucuronides measured by conditioned place preference and locomotor activity
Pharmacol Biochem Behav, 93 (1), 1-9
DOI 10.1016/j.pbb.2009.03.013, PubMed 19351545
Publications 2008
Synapsin-dependent development of glutamatergic synaptic vesicles and presynaptic plasticity in postnatal mouse brain
Neuroscience, 158 (1), 231-41
DOI 10.1016/j.neuroscience.2008.05.055, PubMed 18606212
Distinct changes in neuronal and astrocytic amino acid neurotransmitter metabolism in mice with reduced numbers of synaptic vesicles
J Neurochem, 105 (6), 2524-34
DOI 10.1111/j.1471-4159.2008.05344.x, PubMed 18346203
Different time schedules affect conditioned place preference after morphine and morphine-6-glucuronide administration
Pharmacol Biochem Behav, 89 (3), 374-83
DOI 10.1016/j.pbb.2008.01.012, PubMed 18308383
Bromadiolone poisoning: LC-MS method and pharmacokinetic data
J Forensic Sci, 53 (4), 993-6
DOI 10.1111/j.1556-4029.2008.00737.x, PubMed 18482378
Publications 2007
2D LC separation and determination of bradykinin in rat muscle tissue dialysate with on-line SPE-HILIC-SPE-RP-MS
Chromatographia, 66 (7-8), 469-474
DOI 10.1365/s10337-007-0341-4
Publications 2006
Absence of synapsin I and II is accompanied by decreases in vesicular transport of specific neurotransmitters
J Neurochem, 96 (5), 1458-66
DOI 10.1111/j.1471-4159.2005.03636.x, PubMed 16478532
Differential development of vesicular glutamate transporters in brain: an in vitro study of cerebellar granule cells
Neurochem Int, 48 (6-7), 579-85
DOI 10.1016/j.neuint.2005.12.027, PubMed 16517018
Conditioned place preference induced by morphine and morphine-6-glucuronide in mice
Pharmacol Biochem Behav, 85 (2), 292-7
DOI 10.1016/j.pbb.2006.08.010, PubMed 17011617
Results of the Two-County trial of mammography screening are not compatible with contemporaneous official Swedish breast cancer statistics
Dan Med Bull, 53 (4), 438-40
PubMed 17150148
WITHDRAWN: Results of the Two-County trial of mammography screening are not compatible with contemporaneous official Swedish breast cancer statistics
Eur J Cancer (in press)
DOI 10.1016/j.ejca.2005.12.016, PubMed 16530407
Publications 2005
Response of circulating immune cells to major gunshot injury, haemorrhage, and acute surgery
Injury, 36 (8), 949-55
DOI 10.1016/j.injury.2004.09.021, PubMed 15982652
Ultrastructural quantification of glutamate receptors at excitatory synapses in hippocampus of synapsin I+II double knock-out mice
Neuroscience, 136 (3), 769-77
DOI 10.1016/j.neuroscience.2005.08.056, PubMed 16344150
Effects on cholinergic markers in rat brain and blood after short and prolonged administration of donepezil
Neurochem Res, 30 (12), 1511-20
DOI 10.1007/s11064-005-8828-6, PubMed 16362770
Soman-induced convulsions in rats terminated with pharmacological agents after 45 min: neuropathology and cognitive performance
Neurotoxicology, 26 (1), 39-48
DOI 10.1016/j.neuro.2004.07.011, PubMed 15527872
Binding of molecular oxygen and alkenes to coordinatively unsaturated bipyridinium metal complexes int the gas phase
International Journal of Mass Spectrometry , 243, p 231-239
PublikaID 452
Determination of bradykinin and arg-bradykinin in rat muscle tissue by microdialysis and capillary column-switching liquid chromatography with mass spectrometric detection
J Sep Sci, 28 (14), 1751-8
DOI 10.1002/jssc.200500062, PubMed 16224970
Publications 2004
Kinin peptides in human trapezius muscle during sustained isometric contraction and their relation to pain
J Appl Physiol (1985), 98 (2), 534-40
DOI 10.1152/japplphysiol.01340.2003, PubMed 15475593
Erk1/2 phosphorylation and reactive oxygen species formation via nitric oxide and Akt-1/Raf-1 crosstalk in cultured rat cerebellar granule cells exposed to the organic solvent 1,2,4-trimethylcyclohexane
Toxicol Sci, 80 (2), 296-303
DOI 10.1093/toxsci/kfh166, PubMed 15141098
Protection against soman-induced seizures in rats: relationship among doses of prophylactics, soman, and adjuncts
Toxicol Appl Pharmacol, 196 (3), 327-36
DOI 10.1016/j.taap.2004.01.007, PubMed 15094303
Spontaneous regression of cancerous tumors detected by mammography screening
JAMA, 292 (21), 2579-80; author reply 2580
DOI 10.1001/jama.292.21.2579, PubMed 15572712
Publications 2003
D-Serine alleviates retrograde amnesia of a visual discrimination task in rats with a lesion of the perirhinal cortex
Brain Res, 979 (1-2), 240-4
DOI 10.1016/s0006-8993(03)02894-4, PubMed 12850593
Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease
Neurochem Res, 28 (2), 319-26
DOI 10.1023/a:1022389503105, PubMed 12608704
Identification of the hydroxyl radical and other reactive oxygen species in human neutrophil granulocytes exposed to a fragment of the amyloid beta peptide
Free Radic Res, 37 (3), 269-79
DOI 10.1080/1071576021000046631, PubMed 12688422
Short- and long-term effects of MDMA ("ecstasy") on synaptosomal and vesicular uptake of neurotransmitters in vitro and ex vivo
Neurochem Int, 43 (4-5), 393-400
DOI 10.1016/s0197-0186(03)00027-5, PubMed 12742084
[Pharmacological modulation of the inflammatory response after gunshot injuries in the pig]
Tidsskr Nor Laegeforen, 123 (8), 1054-7
PubMed 12760219
Hydrocortisone and the mitogen-activated protein kinase inhibitor U0126 acutely suppress reactive oxygen species generation from circulating granulocytes after gunshot injuries in the pig
Crit Care Med, 31 (1), 166-70
DOI 10.1097/00003246-200301000-00026, PubMed 12545011
Evaluation of the probes 2',7'-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation
Biochem Pharmacol, 65 (10), 1575-82
DOI 10.1016/s0006-2952(03)00083-2, PubMed 12754093
Publications 2002
Effects of scopolamine and D-cycloserine on non-spatial reference memory in rats
Behav Brain Res, 129 (1-2), 211-6
DOI 10.1016/s0166-4328(01)00318-7, PubMed 11809513
Vasopeptidase inhibitors: a bradykinin link
Lancet, 359 (9312), 1157-8
DOI 10.1016/S0140-6736(02)08142-4, PubMed 11943297
Contraction-related factors affect the concentration of a kallidin-like peptide in rat muscle tissue
J Physiol, 544 (Pt 1), 127-36
DOI 10.1113/jphysiol.2002.025106, PubMed 12356886
Publications 2001
The oxidative power of protonated hydrogen peroxide
Angewandte Chemie, 113, p. 1345-1349
PublikaID 450
Publications 2000
Mediatiors for hydrogenation of carbon monoxide: theoretical study of addition of H2 to HCO+ in the presence of CO or H2O
International Journal of Mass Spectrometry , 201, p. 179-185
PublikaID 448
Gas phase reactivity of small cationic cobalt clusters towards methanol
Chemical Physics , 262, p. 169-177
PublikaID 449
Publications 1997
Loss of H2 from CH2NH2+ and NHNH2+. Reaction mechanisms and dynamics from observation of metastable ion fragmentations and ab initio calculations
International Journal of Mass Spectrometry and Ion Processes, 167/168, p 117-126
PublikaID 447
Publications 1995
Loss of H-2 from CH3NH3+, CH3OH2+ and CH3FH+ - Reaction-Mechanisms and Dynamics from Observation of Metastable Ion Fragmentations and Ab-Initio Calculations Reaction-Mechanisms
Europeamn Mass Spectrometry, 1 (2), 121-129
PublikaID 366