Publications 2023

Bogen IL, Boix F, Andersen JM, Steinsland S, Nerem E, Mørland J (2023)
Heroin metabolism in human blood and its impact for the design of an immunotherapeutic approach against heroin effects
Basic Clin Pharmacol Toxicol, 133 (4), 418-427
DOI 10.1111/bcpt.13926, PubMed 37452619

Hansen JS, Boix F, Hasselstrøm JB, Sørensen LK, Kjolby M, Gustavsen S, Hansen RM, Petersen T, Sellebjerg F, Kasch H, Rasmussen PV, Finnerup NB, Saedder EA, Svendsen KB (2023)
Pharmacokinetics and pharmacodynamics of cannabis-based medicine in a patient population included in a randomized, placebo-controlled, clinical trial
Clin Transl Sci, 17 (1), e13685
DOI 10.1111/cts.13685, PubMed 38054364

Rajalingam D, Boix F, Khoder A, Andersen JM, Paulsen RE (2023)
Distribution of morphine and methadone to the brain in a developmental chicken embryo model
Toxicol Appl Pharmacol, 479, 116731
DOI 10.1016/j.taap.2023.116731, PubMed 37866706

Publications 2022

D'Ottavio G, Reverte I, Ragozzino D, Meringolo M, Milella MS, Boix F, Venniro M, Badiani A, Caprioli D (2022)
Increased heroin intake and relapse vulnerability in intermittent relative to continuous self-administration: Sex differences in rats
Br J Pharmacol, 180 (7), 910-926
DOI 10.1111/bph.15791, PubMed 34986504

Publications 2021

Andersen JM, Bogen IL, Karinen R, Brochmann GW, Mørland J, Vindenes V, Boix F (2021)
Does the preparation for intravenous administration affect the composition of heroin injections? A controlled laboratory study
Addiction, 116 (11), 3104-3112
DOI 10.1111/add.15492, PubMed 33739552

Boix F (2021)
[Is the conclusion reliable?]
Tidsskr Nor Laegeforen, 141 (7)
DOI 10.4045/tidsskr.21.0306, PubMed 33950652

Yadav A, Verhaegen S, Hadera MG, Berntsen HF, Berg V, Lyche JL, Sabaredzovic A, Haug LS, Myhre O, Zimmer KE, Paulsen RE, Ropstad E, Boix F (2021)
Peripherally administered persistent organic pollutants distribute to the brain of developing chicken embryo in concentrations relevant for human exposure
Neurotoxicology, 88, 79-87
DOI 10.1016/j.neuro.2021.10.013, PubMed 34757084

Publications 2020

Andersen JM, Opdal SH, Müller CP, Boix F (2020)
CaMKII is activated in opioid induced conditioned place preference, but αCaMKII Thr286 autophosphorylation is not necessary for its establishment
Behav Brain Res, 390, 112676
DOI 10.1016/j.bbr.2020.112676, PubMed 32407818

Rhein C, Mühle C, Lenz B, Richter-Schmidinger T, Kogias G, Boix F, Lourdusamy A, Dörfler A, Peters O, Ramirez A, Jessen F, Maier W, Hüll M, Frölich L, Teipel S, Wiltfang J, Kornhuber J, Müller CP (2020)
Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly
Brain Res Bull, 161, 13-20
DOI 10.1016/j.brainresbull.2020.05.001, PubMed 32418901

Publications 2019

Kvello AMS, Andersen JM, Boix F, Mørland J, Bogen IL (2019)
The role of 6-acetylmorphine in heroin-induced reward and locomotor sensitization in mice
Addict Biol, 25 (2), e12727
DOI 10.1111/adb.12727, PubMed 30788879

Publications 2018

Avvisati R, Bogen IL, Andersen JM, Vindenes V, Mørland J, Badiani A, Boix F (2018)
The active heroin metabolite 6-acetylmorphine has robust reinforcing effects as assessed by self-administration in the rat
Neuropharmacology, 150, 192-199
DOI 10.1016/j.neuropharm.2018.12.023, PubMed 30578794

Publications 2017

Hofer T, Duale N, Muusse M, Eide DM, Dahl H, Boix F, Andersen JM, Olsen AK, Myhre O (2017)
Restoration of Cognitive Performance in Mice Carrying a Deficient Allele of 8-Oxoguanine DNA Glycosylase by X-ray Irradiation
Neurotox Res, 33 (4), 824-836
DOI 10.1007/s12640-017-9833-7, PubMed 29101721

Publications 2016

Eriksen GS, Andersen JM, Boix F, Bergh MS, Vindenes V, Rice KC, Huestis MA, Mørland J (2016)
Comparison of (+)- and (-)-Naloxone on the Acute Psychomotor-Stimulating Effects of Heroin, 6-Acetylmorphine, and Morphine in Mice
J Pharmacol Exp Ther, 358 (2), 209-15
DOI 10.1124/jpet.116.233544, PubMed 27278234

Publications 2014

Bogen IL, Boix F, Nerem E, Mørland J, Andersen JM (2014)
A monoclonal antibody specific for 6-monoacetylmorphine reduces acute heroin effects in mice
J Pharmacol Exp Ther, 349 (3), 568-76
DOI 10.1124/jpet.113.212035, PubMed 24700886

Eriksen GS, Andersen JM, Boix F, Mørland J (2014)
3-Methoxynaltrexone is not a selective antagonist for the acute psychomotor stimulating effects of heroin and 6-monoacetylmorphine in mice
Pharmacol Biochem Behav, 122, 82-8
DOI 10.1016/j.pbb.2014.03.018, PubMed 24699386

Vindenes V, Boix F, Koksæter P, Strand MC, Bachs L, Mørland J, Gjerde H (2014)
Drugged driving arrests in Norway before and after the implementation of per se law
Forensic Sci Int, 245, 171-7
DOI 10.1016/j.forsciint.2014.10.038, PubMed 25447190

Publications 2013

Vindenes V, Strand DH, Kristoffersen L, Boix F, Mørland J (2013)
Has the intake of THC by cannabis users changed over the last decade? Evidence of increased exposure by analysis of blood THC concentrations in impaired drivers
Forensic Sci Int, 226 (1-3), 197-201
DOI 10.1016/j.forsciint.2013.01.017, PubMed 23415163

Publications 2011

Boix F, Andersen JM, Mørland J (2011)
Pharmacokinetic modeling of subcutaneous heroin and its metabolites in blood and brain of mice
Addict Biol, 18 (1), 1-7
DOI 10.1111/j.1369-1600.2010.00298.x, PubMed 21481103

Publications 2009

Andersen JM, Ripel A, Boix F, Normann PT, Mørland J (2009)
Increased locomotor activity induced by heroin in mice: pharmacokinetic demonstration of heroin acting as a prodrug for the mediator 6-monoacetylmorphine in vivo
J Pharmacol Exp Ther, 331 (1), 153-61
DOI 10.1124/jpet.109.152462, PubMed 19541908

Vindenes V, Pettersen BS, Gottås A, Christiansen NL, Boix F, Mørland J (2009)
Different effects on dopamine release in nucleus accumbens in mice by the morphine metabolites morphine-6-glucuronide and morphine-3-glucuronide
Basic Clin Pharmacol Toxicol, 105 (5), 357-60
DOI 10.1111/j.1742-7843.2009.00451.x, PubMed 19663818

Vindenes V, Ripel A, Handal M, Boix F, Mørland J (2009)
Interactions between morphine and the morphine-glucuronides measured by conditioned place preference and locomotor activity
Pharmacol Biochem Behav, 93 (1), 1-9
DOI 10.1016/j.pbb.2009.03.013, PubMed 19351545

Publications 2008

Vindenes V, Handal M, Ripel A, Thaulow CH, Vindenes HB, Boix F, Mørland J (2008)
Different time schedules affect conditioned place preference after morphine and morphine-6-glucuronide administration
Pharmacol Biochem Behav, 89 (3), 374-83
DOI 10.1016/j.pbb.2008.01.012, PubMed 18308383

Publications 2007

Wilson SR, Jankowski M, Pepaj M, Mihailova A, Boix F, Truyols GV, Lundanes E, Greibrokk T (2007)
2D LC separation and determination of bradykinin in rat muscle tissue dialysate with on-line SPE-HILIC-SPE-RP-MS
Chromatographia, 66 (7-8), 469-474
DOI 10.1365/s10337-007-0341-4

Publications 2006

Vindenes V, Handal M, Ripel A, Boix F, Mørland J (2006)
Conditioned place preference induced by morphine and morphine-6-glucuronide in mice
Pharmacol Biochem Behav, 85 (2), 292-7
DOI 10.1016/j.pbb.2006.08.010, PubMed 17011617

Publications 2005

Wilson SR, Boix F, Holm A, Molander P, Lundanes E, Greibrokk T (2005)
Determination of bradykinin and arg-bradykinin in rat muscle tissue by microdialysis and capillary column-switching liquid chromatography with mass spectrometric detection
J Sep Sci, 28 (14), 1751-8
DOI 10.1002/jssc.200500062, PubMed 16224970

Publications 2004

Boix F, Røe C, Rosenborg L, Knardahl S (2004)
Kinin peptides in human trapezius muscle during sustained isometric contraction and their relation to pain
J Appl Physiol (1985), 98 (2), 534-40
DOI 10.1152/japplphysiol.01340.2003, PubMed 15475593

Publications 2002

Boix F (2002)
Vasopeptidase inhibitors: a bradykinin link
Lancet, 359 (9312), 1157-8
DOI 10.1016/S0140-6736(02)08142-4, PubMed 11943297

Boix F, Rosenborg L, Hilgenfeldt U, Knardahl S (2002)
Contraction-related factors affect the concentration of a kallidin-like peptide in rat muscle tissue
J Physiol, 544 (Pt 1), 127-36
DOI 10.1113/jphysiol.2002.025106, PubMed 12356886