Inger Lise Bogen
- Group Leader, Senior Scientist, Associate Professor; MSc Pharm, PhD
- +47 97 04 15 88
Publications 2024
Metabolite markers for three synthetic tryptamines N-ethyl-N-propyltryptamine, 4-hydroxy-N-ethyl-N-propyltryptamine, and 5-methoxy-N-ethyl-N-propyltryptamine
Drug Test Anal (in press)
DOI 10.1002/dta.3668, PubMed 38459837
Role of aquaporin-4 polarization in extracellular solute clearance
Fluids Barriers CNS, 21 (1), 28
DOI 10.1186/s12987-024-00527-7, PubMed 38532513
Effects of prenatal exposure to methadone or buprenorphine and maternal separation on anxiety-like behavior in rats
Drug Alcohol Depend, 262, 111367
DOI 10.1016/j.drugalcdep.2024.111367, PubMed 39003831
Publications 2023
Heroin metabolism in human blood and its impact for the design of an immunotherapeutic approach against heroin effects
Basic Clin Pharmacol Toxicol, 133 (4), 418-427
DOI 10.1111/bcpt.13926, PubMed 37452619
Scalable production of tissue-like vascularized liver organoids from human PSCs
Exp Mol Med, 55 (9), 2005-2024
DOI 10.1038/s12276-023-01074-1, PubMed 37653039
Publications 2022
"Organ-in-a-Column" Coupled On-line with Liquid Chromatography-Mass Spectrometry
Anal Chem, 94 (50), 17677-17684
DOI 10.1021/acs.analchem.2c04530, PubMed 36484723
Publications 2021
Does the preparation for intravenous administration affect the composition of heroin injections? A controlled laboratory study
Addiction, 116 (11), 3104-3112
DOI 10.1111/add.15492, PubMed 33739552
Pharmacokinetics and pharmacodynamics of cyclopropylfentanyl in male rats
Psychopharmacology (Berl), 238 (12), 3629-3641
DOI 10.1007/s00213-021-05981-x, PubMed 34613431
Discovering the major metabolites of the three novel fentanyl analogues 3-methylcrotonylfentanyl, furanylbenzylfentanyl, and 4-fluorocyclopropylbenzylfentanyl for forensic case work
Forensic Toxicol., 39 (1), 167-178
DOI 10.1007/s11419-020-00560-9
Electromembrane Extraction and Mass Spectrometry for Liver Organoid Drug Metabolism Studies
Anal Chem, 93 (7), 3576-3585
DOI 10.1021/acs.analchem.0c05082, PubMed 33534551
Comparative Neuropharmacology and Pharmacokinetics of Methamphetamine and Its Thiophene Analog Methiopropamine in Rodents
Int J Mol Sci, 22 (21)
DOI 10.3390/ijms222112002, PubMed 34769427
Publications 2020
Selectivity and sensitivity of urine fentanyl test strips to detect fentanyl analogues in illicit drugs
Int J Drug Policy, 90, 103065
DOI 10.1016/j.drugpo.2020.103065, PubMed 33333419
Prenatal exposure to methadone or buprenorphine alters µ-opioid receptor binding and downstream signaling in the rat brain
Int J Dev Neurosci, 80 (5), 443-453
DOI 10.1002/jdn.10043, PubMed 32484968
Prenatal exposure to methadone or buprenorphine impairs cognitive performance in young adult rats
Drug Alcohol Depend, 212, 108008
DOI 10.1016/j.drugalcdep.2020.108008, PubMed 32402939
Publications 2019
Evidence for nonlinear accumulation of the ultrapotent fentanyl analog, carfentanil, after systemic administration to male rats
Neuropharmacology, 158, 107596
DOI 10.1016/j.neuropharm.2019.04.002, PubMed 30965021
Distinguishing Between Cyclopropylfentanyl and Crotonylfentanyl by Methods Commonly Available in the Forensic Laboratory
Ther Drug Monit, 41 (4), 519-527
DOI 10.1097/FTD.0000000000000617, PubMed 30807539
High Accumulation of Methadone Compared with Buprenorphine in Fetal Rat Brain after Maternal Exposure
J Pharmacol Exp Ther, 371 (1), 130-137
DOI 10.1124/jpet.119.259531, PubMed 31358559
The role of 6-acetylmorphine in heroin-induced reward and locomotor sensitization in mice
Addict Biol, 25 (2), e12727
DOI 10.1111/adb.12727, PubMed 30788879
Publications 2018
The active heroin metabolite 6-acetylmorphine has robust reinforcing effects as assessed by self-administration in the rat
Neuropharmacology, 150, 192-199
DOI 10.1016/j.neuropharm.2018.12.023, PubMed 30578794
Addressing the Fentanyl Analogue Epidemic by Multiplex UHPLC-MS/MS Analysis of Whole Blood
Ther Drug Monit, 40 (6), 738-748
DOI 10.1097/FTD.0000000000000564, PubMed 30157097
A Monoclonal Antibody against 6-Acetylmorphine Protects Female Mice Offspring from Adverse Behavioral Effects Induced by Prenatal Heroin Exposure
J Pharmacol Exp Ther, 368 (1), 106-115
DOI 10.1124/jpet.118.251504, PubMed 30361238
Publications 2017
Determination of adrenaline, noradrenaline and corticosterone in rodent blood by ion pair reversed phase UHPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 1072, 161-172
DOI 10.1016/j.jchromb.2017.11.016, PubMed 29175696
The fungal neurotoxin penitrem A induces the production of reactive oxygen species in human neutrophils at submicromolar concentrations
Toxicology, 392, 64-70
DOI 10.1016/j.tox.2017.10.008, PubMed 29037868
Studies on Para-Methoxymethamphetamine (PMMA) Metabolite Pattern and Influence of CYP2D6 Genetics in Human Liver Microsomes and Authentic Samples from Fatal PMMA Intoxications
Drug Metab Dispos, 45 (12), 1326-1335
DOI 10.1124/dmd.117.077263, PubMed 28978661
Publications 2016
Validated methods for determination of neurotransmitters and metabolites in rodent brain tissue and extracellular fluid by reversed phase UHPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 1028, 120-129
DOI 10.1016/j.jchromb.2016.06.011, PubMed 27336704
Low-Chlorinated Non-Dioxin-like Polychlorinated Biphenyls Present in Blood and Breast Milk Induce Higher Levels of Reactive Oxygen Species in Neutrophil Granulocytes than High-Chlorinated Congeners
Basic Clin Pharmacol Toxicol, 119 (6), 588-597
DOI 10.1111/bcpt.12620, PubMed 27194217
Pharmacological Effects of a Monoclonal Antibody against 6-Monoacetylmorphine upon Heroin-Induced Locomotor Activity and Pharmacokinetics in Mice
J Pharmacol Exp Ther, 358 (2), 181-9
DOI 10.1124/jpet.116.233510, PubMed 27217591
Is toxicity of PMMA (paramethoxymethamphetamine) associated with cytochrome P450 pharmacogenetics?
Forensic Sci Int, 261, 137-47
DOI 10.1016/j.forsciint.2016.02.027, PubMed 26930544
Publications 2014
A monoclonal antibody specific for 6-monoacetylmorphine reduces acute heroin effects in mice
J Pharmacol Exp Ther, 349 (3), 568-76
DOI 10.1124/jpet.113.212035, PubMed 24700886
Effects of long-term exposure of 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy") on neuronal transmitter transport, brain immuno-regulatory systems and progression of experimental periodontitis in rats
Neurochem Int, 72, 30-6
DOI 10.1016/j.neuint.2014.04.002, PubMed 24726767
Toxicological profile of ultrapure 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in adult rats
PLoS One, 9 (8), e104639
DOI 10.1371/journal.pone.0104639, PubMed 25137063
Publications 2013
Mechanisms of penitrem-induced cerebellar granule neuron death in vitro: possible involvement of GABAA receptors and oxidative processes
Neurotoxicology, 35, 129-36
DOI 10.1016/j.neuro.2013.01.004, PubMed 23313729
Publications 2012
Marine Ο-3 polyunsaturated fatty acids induce sex-specific changes in reinforcer-controlled behaviour and neurotransmitter metabolism in a spontaneously hypertensive rat model of ADHD
Behav Brain Funct, 8, 56
DOI 10.1186/1744-9081-8-56, PubMed 23228189
Synapsins I and II are not required for insulin secretion from mouse pancreatic β-cells
Endocrinology, 153 (5), 2112-9
DOI 10.1210/en.2011-1702, PubMed 22334712
Publications 2011
Glutamatergic neurotransmission in the synapsin I and II double knock-out mouse
Semin Cell Dev Biol, 22 (4), 400-7
DOI 10.1016/j.semcdb.2011.07.004, PubMed 21827868
Publications 2009
The importance of synapsin I and II for neurotransmitter levels and vesicular storage in cholinergic, glutamatergic and GABAergic nerve terminals
Neurochem Int, 55 (1-3), 13-21
DOI 10.1016/j.neuint.2009.02.006, PubMed 19428802
Publications 2008
Synapsin-dependent development of glutamatergic synaptic vesicles and presynaptic plasticity in postnatal mouse brain
Neuroscience, 158 (1), 231-41
DOI 10.1016/j.neuroscience.2008.05.055, PubMed 18606212
Distinct changes in neuronal and astrocytic amino acid neurotransmitter metabolism in mice with reduced numbers of synaptic vesicles
J Neurochem, 105 (6), 2524-34
DOI 10.1111/j.1471-4159.2008.05344.x, PubMed 18346203
Publications 2006
Absence of synapsin I and II is accompanied by decreases in vesicular transport of specific neurotransmitters
J Neurochem, 96 (5), 1458-66
DOI 10.1111/j.1471-4159.2005.03636.x, PubMed 16478532
Differential development of vesicular glutamate transporters in brain: an in vitro study of cerebellar granule cells
Neurochem Int, 48 (6-7), 579-85
DOI 10.1016/j.neuint.2005.12.027, PubMed 16517018
Publications 2005
Response of circulating immune cells to major gunshot injury, haemorrhage, and acute surgery
Injury, 36 (8), 949-55
DOI 10.1016/j.injury.2004.09.021, PubMed 15982652
Ultrastructural quantification of glutamate receptors at excitatory synapses in hippocampus of synapsin I+II double knock-out mice
Neuroscience, 136 (3), 769-77
DOI 10.1016/j.neuroscience.2005.08.056, PubMed 16344150
Effects on cholinergic markers in rat brain and blood after short and prolonged administration of donepezil
Neurochem Res, 30 (12), 1511-20
DOI 10.1007/s11064-005-8828-6, PubMed 16362770
Publications 2004
Erk1/2 phosphorylation and reactive oxygen species formation via nitric oxide and Akt-1/Raf-1 crosstalk in cultured rat cerebellar granule cells exposed to the organic solvent 1,2,4-trimethylcyclohexane
Toxicol Sci, 80 (2), 296-303
DOI 10.1093/toxsci/kfh166, PubMed 15141098
Publications 2003
Short- and long-term effects of MDMA ("ecstasy") on synaptosomal and vesicular uptake of neurotransmitters in vitro and ex vivo
Neurochem Int, 43 (4-5), 393-400
DOI 10.1016/s0197-0186(03)00027-5, PubMed 12742084