Jannike Mørch Andersen
- Head of Unit, Associate Professor; PhD
- +47 23 01 30 42
Publications 2024
Maternal exposure to buprenorphine, but not methadone, during pregnancy reduces social play behavior across two generations of offspring
Psychopharmacology (Berl) (in press)
DOI 10.1007/s00213-024-06718-2, PubMed 39633163
Effects of prenatal exposure to methadone or buprenorphine and maternal separation on anxiety-like behavior in rats
Drug Alcohol Depend, 262, 111367
DOI 10.1016/j.drugalcdep.2024.111367, PubMed 39003831
Publications 2023
Heroin metabolism in human blood and its impact for the design of an immunotherapeutic approach against heroin effects
Basic Clin Pharmacol Toxicol, 133 (4), 418-427
DOI 10.1111/bcpt.13926, PubMed 37452619
Distribution of morphine and methadone to the brain in a developmental chicken embryo model
Toxicol Appl Pharmacol, 479, 116731
DOI 10.1016/j.taap.2023.116731, PubMed 37866706
Publications 2021
Does the preparation for intravenous administration affect the composition of heroin injections? A controlled laboratory study
Addiction, 116 (11), 3104-3112
DOI 10.1111/add.15492, PubMed 33739552
Comparative Neuropharmacology and Pharmacokinetics of Methamphetamine and Its Thiophene Analog Methiopropamine in Rodents
Int J Mol Sci, 22 (21)
DOI 10.3390/ijms222112002, PubMed 34769427
Chicken embryo as animal model to study drug distribution to the developing brain
J Pharmacol Toxicol Methods, 112, 107105
DOI 10.1016/j.vascn.2021.107105, PubMed 34284116
Publications 2020
Prenatal exposure to methadone or buprenorphine and long-term outcomes: A meta-analysis
Early Hum Dev, 143, 104997
DOI 10.1016/j.earlhumdev.2020.104997, PubMed 32146140
CaMKII is activated in opioid induced conditioned place preference, but αCaMKII Thr286 autophosphorylation is not necessary for its establishment
Behav Brain Res, 390, 112676
DOI 10.1016/j.bbr.2020.112676, PubMed 32407818
Prenatal exposure to methadone or buprenorphine alters µ-opioid receptor binding and downstream signaling in the rat brain
Int J Dev Neurosci, 80 (5), 443-453
DOI 10.1002/jdn.10043, PubMed 32484968
Prenatal exposure to methadone or buprenorphine impairs cognitive performance in young adult rats
Drug Alcohol Depend, 212, 108008
DOI 10.1016/j.drugalcdep.2020.108008, PubMed 32402939
Publications 2019
Opioid receptor-mediated changes in the NMDA receptor in developing rat and chicken
Int J Dev Neurosci, 78, 19-27
DOI 10.1016/j.ijdevneu.2019.07.009, PubMed 31351113
High Accumulation of Methadone Compared with Buprenorphine in Fetal Rat Brain after Maternal Exposure
J Pharmacol Exp Ther, 371 (1), 130-137
DOI 10.1124/jpet.119.259531, PubMed 31358559
The role of 6-acetylmorphine in heroin-induced reward and locomotor sensitization in mice
Addict Biol, 25 (2), e12727
DOI 10.1111/adb.12727, PubMed 30788879
Publications 2018
The active heroin metabolite 6-acetylmorphine has robust reinforcing effects as assessed by self-administration in the rat
Neuropharmacology, 150, 192-199
DOI 10.1016/j.neuropharm.2018.12.023, PubMed 30578794
A Monoclonal Antibody against 6-Acetylmorphine Protects Female Mice Offspring from Adverse Behavioral Effects Induced by Prenatal Heroin Exposure
J Pharmacol Exp Ther, 368 (1), 106-115
DOI 10.1124/jpet.118.251504, PubMed 30361238
Can measurements of heroin metabolites in post-mortem matrices other than peripheral blood indicate if death was rapid or delayed?
Forensic Sci Int, 290, 121-128
DOI 10.1016/j.forsciint.2018.06.041, PubMed 30015276
Metabolites of Heroin in Several Different Post-mortem Matrices
J Anal Toxicol, 42 (5), 311-320
DOI 10.1093/jat/bky002, PubMed 29409037
Publications 2017
Determination of adrenaline, noradrenaline and corticosterone in rodent blood by ion pair reversed phase UHPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 1072, 161-172
DOI 10.1016/j.jchromb.2017.11.016, PubMed 29175696
Restoration of Cognitive Performance in Mice Carrying a Deficient Allele of 8-Oxoguanine DNA Glycosylase by X-ray Irradiation
Neurotox Res, 33 (4), 824-836
DOI 10.1007/s12640-017-9833-7, PubMed 29101721
Publications 2016
Comparison of (+)- and (-)-Naloxone on the Acute Psychomotor-Stimulating Effects of Heroin, 6-Acetylmorphine, and Morphine in Mice
J Pharmacol Exp Ther, 358 (2), 209-15
DOI 10.1124/jpet.116.233544, PubMed 27278234
Pharmacological Effects of a Monoclonal Antibody against 6-Monoacetylmorphine upon Heroin-Induced Locomotor Activity and Pharmacokinetics in Mice
J Pharmacol Exp Ther, 358 (2), 181-9
DOI 10.1124/jpet.116.233510, PubMed 27217591
Publications 2015
Rapport om konsekvenser for fosteret/barnet ved bruk av rusmidler/avhengighetsskapende legemidler i svangerskapet
Helsedirektoratet
PublikaID 460
Publications 2014
A monoclonal antibody specific for 6-monoacetylmorphine reduces acute heroin effects in mice
J Pharmacol Exp Ther, 349 (3), 568-76
DOI 10.1124/jpet.113.212035, PubMed 24700886
3-Methoxynaltrexone is not a selective antagonist for the acute psychomotor stimulating effects of heroin and 6-monoacetylmorphine in mice
Pharmacol Biochem Behav, 122, 82-8
DOI 10.1016/j.pbb.2014.03.018, PubMed 24699386
Pharmacokinetic interactions between ethanol and heroin: a study on post-mortem cases
Forensic Sci Int, 242, 127-134
DOI 10.1016/j.forsciint.2014.06.032, PubMed 25050840
Publications 2013
The interference of ethanol with heroin-stimulated psychomotor activation in mice is not related to changed brain concentrations of the active metabolites 6MAM or morphine
Basic Clin Pharmacol Toxicol, 114 (2), 197-201
DOI 10.1111/bcpt.12133, PubMed 24102968
Less glucuronidation of morphine in the presence of ethanol in vivo
Eur J Clin Pharmacol, 69 (9), 1683-7
DOI 10.1007/s00228-013-1533-5, PubMed 23739999
Publications 2012
Long-term methadone treatment reduces phosphorylation of CaMKII in rat brain
J Pharm Pharmacol, 64 (6), 843-7
DOI 10.1111/j.2042-7158.2012.01469.x, PubMed 22571262
Long-term methadone treatment reduces phosphorylation of CaMKII in rat brain
J Pharm Pharmacol, Jun;64(6), 843-7
DOI 10.1111/j.2042-7158.2012.01469.x, PublikaID 276
Methadone does not alter key parameters of adult hippocampal neurogenesis in the heroin-naïve rat
Neurosci Lett, 516 (1), 99-104
DOI 10.1016/j.neulet.2012.03.066, PubMed 22487733
Publications 2011
Long-term methadone treatment impairs novelty preference in rats both when present and absent in brain tissue
Pharmacol Biochem Behav, 98 (3), 412-6
DOI 10.1016/j.pbb.2011.02.017, PubMed 21352846
Pharmacokinetic modeling of subcutaneous heroin and its metabolites in blood and brain of mice
Addict Biol, 18 (1), 1-7
DOI 10.1111/j.1369-1600.2010.00298.x, PubMed 21481103
Publications 2009
Increased locomotor activity induced by heroin in mice: pharmacokinetic demonstration of heroin acting as a prodrug for the mediator 6-monoacetylmorphine in vivo
J Pharmacol Exp Ther, 331 (1), 153-61
DOI 10.1124/jpet.109.152462, PubMed 19541908
Determination of heroin and its main metabolites in small sample volumes of whole blood and brain tissue by reversed-phase liquid chromatography-tandem mass spectrometry
J Anal Toxicol, 33 (7), 345-50
DOI 10.1093/jat/33.7.345, PubMed 19796503
Publications 2006
Results of the Two-County trial of mammography screening are not compatible with contemporaneous official Swedish breast cancer statistics
Dan Med Bull, 53 (4), 438-40
PubMed 17150148
WITHDRAWN: Results of the Two-County trial of mammography screening are not compatible with contemporaneous official Swedish breast cancer statistics
Eur J Cancer (in press)
DOI 10.1016/j.ejca.2005.12.016, PubMed 16530407
Publications 2005
Soman-induced convulsions in rats terminated with pharmacological agents after 45 min: neuropathology and cognitive performance
Neurotoxicology, 26 (1), 39-48
DOI 10.1016/j.neuro.2004.07.011, PubMed 15527872
Publications 2004
Protection against soman-induced seizures in rats: relationship among doses of prophylactics, soman, and adjuncts
Toxicol Appl Pharmacol, 196 (3), 327-36
DOI 10.1016/j.taap.2004.01.007, PubMed 15094303
Spontaneous regression of cancerous tumors detected by mammography screening
JAMA, 292 (21), 2579-80; author reply 2580
DOI 10.1001/jama.292.21.2579, PubMed 15572712
Publications 2003
D-Serine alleviates retrograde amnesia of a visual discrimination task in rats with a lesion of the perirhinal cortex
Brain Res, 979 (1-2), 240-4
DOI 10.1016/s0006-8993(03)02894-4, PubMed 12850593
Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease
Neurochem Res, 28 (2), 319-26
DOI 10.1023/a:1022389503105, PubMed 12608704
Identification of the hydroxyl radical and other reactive oxygen species in human neutrophil granulocytes exposed to a fragment of the amyloid beta peptide
Free Radic Res, 37 (3), 269-79
DOI 10.1080/1071576021000046631, PubMed 12688422
Glysin som del av det akutte resusciteringsregimet etter skuddskader hos gris: modulering av den tidlige inflammatoriske responsen
FFI, Kjeller, 20 s.
BIBSYS 030747864, ISBN 82-464-0696-5
[Pharmacological modulation of the inflammatory response after gunshot injuries in the pig]
Tidsskr Nor Laegeforen, 123 (8), 1054-7
PubMed 12760219
Hydrocortisone and the mitogen-activated protein kinase inhibitor U0126 acutely suppress reactive oxygen species generation from circulating granulocytes after gunshot injuries in the pig
Crit Care Med, 31 (1), 166-70
DOI 10.1097/00003246-200301000-00026, PubMed 12545011
Evaluation of the probes 2',7'-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation
Biochem Pharmacol, 65 (10), 1575-82
DOI 10.1016/s0006-2952(03)00083-2, PubMed 12754093
Publications 2002
Effects of scopolamine and D-cycloserine on non-spatial reference memory in rats
Behav Brain Res, 129 (1-2), 211-6
DOI 10.1016/s0166-4328(01)00318-7, PubMed 11809513
Tidlig behandling med hydrokortison og/eller U-0126 hemmer syntesen av frie oksygenradikaler etter skuddskader hos gris
FFI, Kjeller, 16 s.
BIBSYS 020531664, ISBN 82-464-0581-0