Jannike Mørch Andersen

  • Head of Unit, Associate Professor; PhD
  • +47 23 01 30 42

Publications 2023

Bogen IL, Boix F, Andersen JM, Steinsland S, Nerem E, Mørland J (2023)
Heroin metabolism in human blood and its impact for the design of an immunotherapeutic approach against heroin effects
Basic Clin Pharmacol Toxicol, 133 (4), 418-427
DOI 10.1111/bcpt.13926, PubMed 37452619

Rajalingam D, Boix F, Khoder A, Andersen JM, Paulsen RE (2023)
Distribution of morphine and methadone to the brain in a developmental chicken embryo model
Toxicol Appl Pharmacol, 479, 116731
DOI 10.1016/j.taap.2023.116731, PubMed 37866706

Publications 2021

Andersen JM, Bogen IL, Karinen R, Brochmann GW, Mørland J, Vindenes V, Boix F (2021)
Does the preparation for intravenous administration affect the composition of heroin injections? A controlled laboratory study
Addiction, 116 (11), 3104-3112
DOI 10.1111/add.15492, PubMed 33739552

Tuv SS, Bergh MS, Andersen JM, Steinsland S, Vindenes V, Baumann MH, Huestis MA, Bogen IL (2021)
Comparative Neuropharmacology and Pharmacokinetics of Methamphetamine and Its Thiophene Analog Methiopropamine in Rodents
Int J Mol Sci, 22 (21)
DOI 10.3390/ijms222112002, PubMed 34769427

Zosen D, Hadera MG, Lumor JS, Andersen JM, Paulsen RE (2021)
Chicken embryo as animal model to study drug distribution to the developing brain
J Pharmacol Toxicol Methods, 112, 107105
DOI 10.1016/j.vascn.2021.107105, PubMed 34284116

Publications 2020

Andersen JM, Høiseth G, Nygaard E (2020)
Prenatal exposure to methadone or buprenorphine and long-term outcomes: A meta-analysis
Early Hum Dev, 143, 104997
DOI 10.1016/j.earlhumdev.2020.104997, PubMed 32146140

Andersen JM, Opdal SH, Müller CP, Boix F (2020)
CaMKII is activated in opioid induced conditioned place preference, but αCaMKII Thr286 autophosphorylation is not necessary for its establishment
Behav Brain Res, 390, 112676
DOI 10.1016/j.bbr.2020.112676, PubMed 32407818

Kongstorp M, Bogen IL, Steinsland S, Nerem E, Salih TW, Stiris T, Andersen JM (2020)
Prenatal exposure to methadone or buprenorphine alters µ-opioid receptor binding and downstream signaling in the rat brain
Int J Dev Neurosci, 80 (5), 443-453
DOI 10.1002/jdn.10043, PubMed 32484968

Kongstorp M, Bogen IL, Stiris T, Andersen JM (2020)
Prenatal exposure to methadone or buprenorphine impairs cognitive performance in young adult rats
Drug Alcohol Depend, 212, 108008
DOI 10.1016/j.drugalcdep.2020.108008, PubMed 32402939

Publications 2019

Fjelldal MF, Hadera MG, Kongstorp M, Austdal LPE, Šulović A, Andersen JM, Paulsen RE (2019)
Opioid receptor-mediated changes in the NMDA receptor in developing rat and chicken
Int J Dev Neurosci, 78, 19-27
DOI 10.1016/j.ijdevneu.2019.07.009, PubMed 31351113

Kongstorp M, Bogen IL, Stiris T, Andersen JM (2019)
High Accumulation of Methadone Compared with Buprenorphine in Fetal Rat Brain after Maternal Exposure
J Pharmacol Exp Ther, 371 (1), 130-137
DOI 10.1124/jpet.119.259531, PubMed 31358559

Kvello AMS, Andersen JM, Boix F, Mørland J, Bogen IL (2019)
The role of 6-acetylmorphine in heroin-induced reward and locomotor sensitization in mice
Addict Biol, 25 (2), e12727
DOI 10.1111/adb.12727, PubMed 30788879

Publications 2018

Avvisati R, Bogen IL, Andersen JM, Vindenes V, Mørland J, Badiani A, Boix F (2018)
The active heroin metabolite 6-acetylmorphine has robust reinforcing effects as assessed by self-administration in the rat
Neuropharmacology, 150, 192-199
DOI 10.1016/j.neuropharm.2018.12.023, PubMed 30578794

Kvello AMS, Andersen JM, Øiestad EL, Steinsland S, Aase A, Mørland J, Bogen IL (2018)
A Monoclonal Antibody against 6-Acetylmorphine Protects Female Mice Offspring from Adverse Behavioral Effects Induced by Prenatal Heroin Exposure
J Pharmacol Exp Ther, 368 (1), 106-115
DOI 10.1124/jpet.118.251504, PubMed 30361238

Thaulow CH, Øiestad ÅML, Rogde S, Andersen JM, Høiseth G, Handal M, Mørland J, Vindenes V (2018)
Can measurements of heroin metabolites in post-mortem matrices other than peripheral blood indicate if death was rapid or delayed?
Forensic Sci Int, 290, 121-128
DOI 10.1016/j.forsciint.2018.06.041, PubMed 30015276

Thaulow CH, Øiestad ÅML, Rogde S, Karinen R, Brochmann GW, Andersen JM, Høiseth G, Handal M, Mørland J, Arnestad M, Øiestad EL, Strand DH, Vindenes V (2018)
Metabolites of Heroin in Several Different Post-mortem Matrices
J Anal Toxicol, 42 (5), 311-320
DOI 10.1093/jat/bky002, PubMed 29409037

Publications 2017

Bergh MS, Bogen IL, Andersen JM, Øiestad ÅML, Berg T (2017)
Determination of adrenaline, noradrenaline and corticosterone in rodent blood by ion pair reversed phase UHPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 1072, 161-172
DOI 10.1016/j.jchromb.2017.11.016, PubMed 29175696

Hofer T, Duale N, Muusse M, Eide DM, Dahl H, Boix F, Andersen JM, Olsen AK, Myhre O (2017)
Restoration of Cognitive Performance in Mice Carrying a Deficient Allele of 8-Oxoguanine DNA Glycosylase by X-ray Irradiation
Neurotox Res, 33 (4), 824-836
DOI 10.1007/s12640-017-9833-7, PubMed 29101721

Publications 2016

Eriksen GS, Andersen JM, Boix F, Bergh MS, Vindenes V, Rice KC, Huestis MA, Mørland J (2016)
Comparison of (+)- and (-)-Naloxone on the Acute Psychomotor-Stimulating Effects of Heroin, 6-Acetylmorphine, and Morphine in Mice
J Pharmacol Exp Ther, 358 (2), 209-15
DOI 10.1124/jpet.116.233544, PubMed 27278234

Kvello AM, Andersen JM, Øiestad EL, Mørland J, Bogen IL (2016)
Pharmacological Effects of a Monoclonal Antibody against 6-Monoacetylmorphine upon Heroin-Induced Locomotor Activity and Pharmacokinetics in Mice
J Pharmacol Exp Ther, 358 (2), 181-9
DOI 10.1124/jpet.116.233510, PubMed 27217591

Publications 2015

Heide G, Andersen JM, Høiseth G (2015)
Rapport om konsekvenser for fosteret/barnet ved bruk av rusmidler/avhengighetsskapende legemidler i svangerskapet
PublikaID 460

Publications 2014

Bogen IL, Boix F, Nerem E, Mørland J, Andersen JM (2014)
A monoclonal antibody specific for 6-monoacetylmorphine reduces acute heroin effects in mice
J Pharmacol Exp Ther, 349 (3), 568-76
DOI 10.1124/jpet.113.212035, PubMed 24700886

Eriksen GS, Andersen JM, Boix F, Mørland J (2014)
3-Methoxynaltrexone is not a selective antagonist for the acute psychomotor stimulating effects of heroin and 6-monoacetylmorphine in mice
Pharmacol Biochem Behav, 122, 82-8
DOI 10.1016/j.pbb.2014.03.018, PubMed 24699386

Thaulow CH, Høiseth G, Andersen JM, Handal M, Mørland J (2014)
Pharmacokinetic interactions between ethanol and heroin: a study on post-mortem cases
Forensic Sci Int, 242, 127-134
DOI 10.1016/j.forsciint.2014.06.032, PubMed 25050840

Publications 2013

Andersen JM, Haugen KS, Ripel A, Mørland J (2013)
The interference of ethanol with heroin-stimulated psychomotor activation in mice is not related to changed brain concentrations of the active metabolites 6MAM or morphine
Basic Clin Pharmacol Toxicol, 114 (2), 197-201
DOI 10.1111/bcpt.12133, PubMed 24102968

Høiseth G, Andersen JM, Mørland J (2013)
Less glucuronidation of morphine in the presence of ethanol in vivo
Eur J Clin Pharmacol, 69 (9), 1683-7
DOI 10.1007/s00228-013-1533-5, PubMed 23739999

Publications 2012

Andersen JM, Klykken C, Mørland J (2012)
Long-term methadone treatment reduces phosphorylation of CaMKII in rat brain
J Pharm Pharmacol, 64 (6), 843-7
DOI 10.1111/j.2042-7158.2012.01469.x, PubMed 22571262

Andersen JM, Klykken C, Mørland J (2012)
Long-term methadone treatment reduces phosphorylation of CaMKII in rat brain
J Pharm Pharmacol, Jun;64(6), 843-7
DOI 10.1111/j.2042-7158.2012.01469.x, PublikaID 276

Sankararaman A, Masiulis I, Richardson DR, Andersen JM, Mørland J, Eisch AJ (2012)
Methadone does not alter key parameters of adult hippocampal neurogenesis in the heroin-naïve rat
Neurosci Lett, 516 (1), 99-104
DOI 10.1016/j.neulet.2012.03.066, PubMed 22487733

Publications 2011

Andersen JM, Olaussen CF, Ripel A, Mørland J (2011)
Long-term methadone treatment impairs novelty preference in rats both when present and absent in brain tissue
Pharmacol Biochem Behav, 98 (3), 412-6
DOI 10.1016/j.pbb.2011.02.017, PubMed 21352846

Boix F, Andersen JM, Mørland J (2011)
Pharmacokinetic modeling of subcutaneous heroin and its metabolites in blood and brain of mice
Addict Biol, 18 (1), 1-7
DOI 10.1111/j.1369-1600.2010.00298.x, PubMed 21481103

Publications 2009

Andersen JM, Ripel A, Boix F, Normann PT, Mørland J (2009)
Increased locomotor activity induced by heroin in mice: pharmacokinetic demonstration of heroin acting as a prodrug for the mediator 6-monoacetylmorphine in vivo
J Pharmacol Exp Ther, 331 (1), 153-61
DOI 10.1124/jpet.109.152462, PubMed 19541908

Karinen R, Andersen JM, Ripel A, Hasvold I, Hopen AB, Mørland J, Christophersen AS (2009)
Determination of heroin and its main metabolites in small sample volumes of whole blood and brain tissue by reversed-phase liquid chromatography-tandem mass spectrometry
J Anal Toxicol, 33 (7), 345-50
DOI 10.1093/jat/33.7.345, PubMed 19796503

Publications 2006

Zahl PH, Gøtzsche PC, Andersen JM, Maehlen J (2006)
Results of the Two-County trial of mammography screening are not compatible with contemporaneous official Swedish breast cancer statistics
Dan Med Bull, 53 (4), 438-40
PubMed 17150148

Zahl PH, Gøtzsche PC, Andersen JM, Mæhlen J (2006)
WITHDRAWN: Results of the Two-County trial of mammography screening are not compatible with contemporaneous official Swedish breast cancer statistics
Eur J Cancer (in press)
DOI 10.1016/j.ejca.2005.12.016, PubMed 16530407

Publications 2005

Myhrer T, Andersen JM, Nguyen NH, Aas P (2005)
Soman-induced convulsions in rats terminated with pharmacological agents after 45 min: neuropathology and cognitive performance
Neurotoxicology, 26 (1), 39-48
DOI 10.1016/j.neuro.2004.07.011, PubMed 15527872

Publications 2004

Myhrer T, Nguyen NH, Andersen JM, Aas P (2004)
Protection against soman-induced seizures in rats: relationship among doses of prophylactics, soman, and adjuncts
Toxicol Appl Pharmacol, 196 (3), 327-36
DOI 10.1016/j.taap.2004.01.007, PubMed 15094303

Zahl PH, Andersen JM, Maehlen J (2004)
Spontaneous regression of cancerous tumors detected by mammography screening
JAMA, 292 (21), 2579-80; author reply 2580
DOI 10.1001/jama.292.21.2579, PubMed 15572712

Publications 2003

Andersen JM, Fonnum F, Myhrer T (2003)
D-Serine alleviates retrograde amnesia of a visual discrimination task in rats with a lesion of the perirhinal cortex
Brain Res, 979 (1-2), 240-4
DOI 10.1016/s0006-8993(03)02894-4, PubMed 12850593

Andersen JM, Myhre O, Fonnum F (2003)
Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease
Neurochem Res, 28 (2), 319-26
DOI 10.1023/a:1022389503105, PubMed 12608704

Andersen JM, Myhre O, Aarnes H, Vestad TA, Fonnum F (2003)
Identification of the hydroxyl radical and other reactive oxygen species in human neutrophil granulocytes exposed to a fragment of the amyloid beta peptide
Free Radic Res, 37 (3), 269-79
DOI 10.1080/1071576021000046631, PubMed 12688422

Gundersen Y, Vaagenes P, Andersen JM, Dreiem A, Haugen AH, Myhre O, Reistad T, Sterri S, Thrane I (2003)
Glysin som del av det akutte resusciteringsregimet etter skuddskader hos gris: modulering av den tidlige inflammatoriske responsen
FFI, Kjeller, 20 s.
BIBSYS 030747864, ISBN 82-464-0696-5

Gundersen Y, Vaagenes P, Myhre O, Andersen JM (2003)
[Pharmacological modulation of the inflammatory response after gunshot injuries in the pig]
Tidsskr Nor Laegeforen, 123 (8), 1054-7
PubMed 12760219

Gundersen Y, Vaagenes P, Myhre O, Andersen JM, Pharo A, Haugen AH, Valoe E, Opstad PK (2003)
Hydrocortisone and the mitogen-activated protein kinase inhibitor U0126 acutely suppress reactive oxygen species generation from circulating granulocytes after gunshot injuries in the pig
Crit Care Med, 31 (1), 166-70
DOI 10.1097/00003246-200301000-00026, PubMed 12545011

Myhre O, Andersen JM, Aarnes H, Fonnum F (2003)
Evaluation of the probes 2',7'-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation
Biochem Pharmacol, 65 (10), 1575-82
DOI 10.1016/s0006-2952(03)00083-2, PubMed 12754093

Publications 2002

Andersen JM, Lindberg V, Myhrer T (2002)
Effects of scopolamine and D-cycloserine on non-spatial reference memory in rats
Behav Brain Res, 129 (1-2), 211-6
DOI 10.1016/s0166-4328(01)00318-7, PubMed 11809513

Gundersen Y, Vaagenes P, Haugen AH, Pharo A, Valø ET, Myhre O, Andersen JM, Sundnes KO, Os Ø, Pillgram-Larsen J (2002)
Tidlig behandling med hydrokortison og/eller U-0126 hemmer syntesen av frie oksygenradikaler etter skuddskader hos gris
FFI, Kjeller, 16 s.
BIBSYS 020531664, ISBN 82-464-0581-0

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