Ellen Jørum

  • Professor; MD, PhD
  • +47 230 73581

Publications 2022

Handwerker H, Jorum E, Schady W, LaMotte R, Schmelz M (2022)
Erik Torebjork, MD PhD, Professor of Clinical Pain Research 1939-2021 Forerunner and lead researcher of human nociceptor research OBITUARY
Eur. J. Pain, 26 (2), 275-279
DOI 10.1002/ejp.1893

Lunden LK, Kleggetveit IP, Schmelz M, Jorum E (2022)
Cold allodynia is correlated to paroxysmal and evoked mechanical pain in complex regional pain syndrome (CRPS)
Scand J Pain, 22 (3), 533-542
DOI 10.1515/sjpain-2021-0208, PubMed 35429156

Norheim AJ, Rannestad B, Howes R, Rein EB, Jørum E, Friedl K, Havenith G, Teien HK, Mercer JB, Melau J, de Weerd L, Smith M, Taylor N, Voie ØA, Bergan-Skar P, Andrews S, Næsheim T, Steinberg T (2022)
Abstracts from The Cold Weather Operations Conference 2021
Int J Circumpolar Health, 81 (1), 2049491
DOI 10.1080/22423982.2022.2049491, PubMed 35275797

Publications 2021

Lunden LK, Jorum E (2021)
The challenge of recognizing severe pain and autonomic abnormalities for early diagnosis of CRPS
Scand J Pain, 21 (3), 548-559
DOI 10.1515/sjpain-2021-0036, PubMed 33838088

Werland F, Hirth M, Rukwied R, Ringkamp M, Turnquist B, Jorum E, Namer B, Schmelz M, Obreja O (2021)
Maximum axonal following frequency separates classes of cutaneous unmyelinated nociceptors in the pig
J Physiol, 599 (5), 1595-1610
DOI 10.1113/JP280269, PubMed 33369733

Publications 2020

Rukwied R, Thomas C, Obreja O, Werland F, Kleggetveit IP, Jorum E, Carr RW, Namer B, Schmelz M (2020)
Slow depolarizing stimuli differentially activate mechanosensitive and silent C nociceptors in human and pig skin
Pain, 161 (9), 2119-2128
DOI 10.1097/j.pain.0000000000001912, PubMed 32379219

Publications 2019

Dukefoss TT, Kleggetveit IP, Helås T, Jørum E (2019)
Pain and small-fiber affection in hereditary neuropathy with liability to pressure palsies (HNPP)
Scand J Pain, 20 (1), 61-68
DOI 10.1515/sjpain-2019-0090, PubMed 31536037

Jørum E, Opstad PK (2019)
A 4-year follow-up of non-freezing cold injury with cold allodynia and neuropathy in 26 naval soldiers
Scand J Pain, 19 (3), 441-451
DOI 10.1515/sjpain-2019-0035, PubMed 30939119

Meents JE, Bressan E, Sontag S, Foerster A, Hautvast P, Rösseler C, Hampl M, Schüler H, Goetzke R, Le TKC, Kleggetveit IP, Le Cann K, Kerth C, Rush AM, Rogers M, Kohl Z, Schmelz M, Wagner W, Jørum E, Namer B, Winner B, Zenke M, Lampert A (2019)
The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell-derived sensory neurons of erythromelalgia patients
Pain, 160 (6), 1327-1341
DOI 10.1097/j.pain.0000000000001511, PubMed 30720580

Publications 2018

Kleggetveit IP, Jørum E (2018)
Diagnosis of carpal tunnel syndrome
Scand J Pain, 18 (3), 333-337
DOI 10.1515/sjpain-2018-0089, PubMed 29894306

Kleggetveit IP, Jørum E (2018)
Reply to the Letter to the Editor by Ly-Pen and Andréu
Scand J Pain, 18 (4), 757
DOI 10.1515/sjpain-2018-0118, PubMed 30145582

Namer B, Schmidt D, Eberhardt E, Maroni M, Dorfmeister E, Kleggetveit IP, Kaluza L, Meents J, Gerlach A, Lin Z, Winterpacht A, Dragicevic E, Kohl Z, Schüttler J, Kurth I, Warncke T, Jorum E, Winner B, Lampert A (2018)
Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors
EBioMedicine, 39, 401-408
DOI 10.1016/j.ebiom.2018.11.042, PubMed 30503201

Publications 2017

Helås T, Sagafos D, Kleggetveit IP, Quiding H, Jönsson B, Segerdahl M, Zhang Z, Salter H, Schmelz M, Jørum E (2017)
Pain thresholds, supra-threshold pain and lidocaine sensitivity in patients with erythromelalgia, including the I848Tmutation in NaV 1.7
Eur J Pain, 21 (8), 1316-1325
DOI 10.1002/ejp.1030, PubMed 28418213

Namer B, Ørstavik K, Schmidt R, Mair N, Kleggetveit IP, Zeidler M, Martha T, Jorum E, Schmelz M, Kalpachidou T, Kress M, Langeslag M (2017)
Changes in Ionic Conductance Signature of Nociceptive Neurons Underlying Fabry Disease Phenotype
Front Neurol, 8, 335
DOI 10.3389/fneur.2017.00335, PubMed 28769867

Publications 2016

Jørum E (2016)
The Sun King's anal fistula
Tidsskr Nor Laegeforen, 136 (14-15), 1244-7
DOI 10.4045/tidsskr.15.0312, PubMed 27554569

Kist AM, Sagafos D, Rush AM, Neacsu C, Eberhardt E, Schmidt R, Lunden LK, Ørstavik K, Kaluza L, Meents J, Zhang Z, Carr TH, Salter H, Malinowsky D, Wollberg P, Krupp J, Kleggetveit IP, Schmelz M, Jørum E, Lampert A, Namer B (2016)
SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing
PLoS One, 11 (9), e0161789
DOI 10.1371/journal.pone.0161789, PubMed 27598514

Kleggetveit IP, Schmidt R, Namer B, Salter H, Helås T, Schmelz M, Jørum E (2016)
Pathological nociceptors in two patients with erythromelalgia-like symptoms and rare genetic Nav 1.9 variants
Brain Behav, 6 (10), e00528
DOI 10.1002/brb3.528, PubMed 27781142

Sagafos D, Kleggetveit IP, Helås T, Schmidt R, Minde J, Namer B, Schmelz M, Jørum E (2016)
Single-Fiber Recordings of Nociceptive Fibers in Patients With HSAN Type V With Congenital Insensitivity to Pain
Clin J Pain, 32 (7), 636-42
DOI 10.1097/AJP.0000000000000303, PubMed 27270876

Publications 2015

Horn MA, Mikaelsen KB, Ferdinandusse S, Jørum E, Mellgren SI, Retterstøl L, Wanders RJ, Tallaksen CM (2015)
Mild phenotype in an adult male with X-linked adrenoleukodystrophy - case report
Clin Case Rep, 4 (2), 177-81
DOI 10.1002/ccr3.434, PubMed 26862418

Jørum E (2015)
Advancing methods for characterizing structure and functions of small nerve fibres in neuropathic conditions
Scand J Pain, 10, 54-56
DOI 10.1016/j.sjpain.2015.09.005, PubMed 28361772

Kleggetveit IP, Skulberg PK, Jørum E (2015)
Complex regional pain syndrome following viper-bite
Scand J Pain, 10, 15-18
DOI 10.1016/j.sjpain.2015.07.005, PubMed 28361765

Lunden LK, Kleggetveit IP, Jørum E (2015)
Delayed diagnosis and worsening of pain following orthopedic surgery in patients with complex regional pain syndrome (CRPS)
Scand J Pain, 11, 27-33
DOI 10.1016/j.sjpain.2015.11.004, PubMed 28850465

Namer B, Ørstavik K, Schmidt R, Kleggetveit IP, Weidner C, Mørk C, Kvernebo MS, Kvernebo K, Salter H, Carr TH, Segerdahl M, Quiding H, Waxman SG, Handwerker HO, Torebjörk HE, Jørum E, Schmelz M (2015)
Specific changes in conduction velocity recovery cycles of single nociceptors in a patient with erythromelalgia with the I848T gain-of-function mutation of Nav1.7
Pain, 156 (9), 1637-1646
DOI 10.1097/j.pain.0000000000000229, PubMed 25993546

Publications 2014

Horn MA, Nilsen KB, Jørum E, Mellgren SI, Tallaksen CM (2014)
Small nerve fiber involvement is frequent in X-linked adrenoleukodystrophy
Neurology, 82 (19), 1678-83
DOI 10.1212/WNL.0000000000000415, PubMed 24719486

Namer B, Schick M, Kleggetveit IP, Ørstavik K, Schmidt R, Jorum E, Torebjörk E, Handwerker H, Schmelz M (2014)
Differential sensitization of silent nociceptors to low pH stimulation by prostaglandin E2 in human volunteers
Eur J Pain, 19 (2), 159-66
DOI 10.1002/ejp.532, PubMed 24890616

Zhang Z, Schmelz M, Segerdahl M, Quiding H, Centerholt C, Juréus A, Carr TH, Whiteley J, Salter H, Kvernebo MS, Ørstavik K, Helås T, Kleggetveit IP, Lunden LK, Jørum E (2014)
Exonic mutations in SCN9A (NaV1.7) are found in a minority of patients with erythromelalgia
Scand J Pain, 5 (4), 217-225
DOI 10.1016/j.sjpain.2014.09.002, PubMed 29911575

Publications 2013

Haugaa KH, Vestervik TT, Andersson S, Amlie JP, Jørum E, Gjerstad L, Taubøll E (2013)
Abnormal electroencephalograms in patients with long QT syndrome
Heart Rhythm, 10 (12), 1877-83
DOI 10.1016/j.hrthm.2013.09.070, PubMed 24080067

Jørum E, Warncke T, Ørstavik K (2013)
[Small-fibre neuropathy]
Tidsskr Nor Laegeforen, 133 (2), 179-83
DOI 10.4045/tidsskr.12.0160, PubMed 23344604

Sveen KA, Karimé B, Jørum E, Mellgren SI, Fagerland MW, Monnier VM, Dahl-Jørgensen K, Hanssen KF (2013)
Small- and large-fiber neuropathy after 40 years of type 1 diabetes: associations with glycemic control and advanced protein glycation: the Oslo Study
Diabetes Care, 36 (11), 3712-7
DOI 10.2337/dc13-0788, PubMed 24026557

Ørstavik K, Kleggetveit IP, Jørum E (2013)
[Microneurography and research on peripheral neuropathic pain]
Tidsskr Nor Laegeforen, 133 (3), 302-5
DOI 10.4045/tidsskr.12.0098, PubMed 23381167

Publications 2012

Jørum E, Torbergsen T, Dietrichs E (2012)
Combined testing of autonomic and sensory dysfunction in patients with unilateral facial flushing and sweating during exercise
Neurophysiol Clin, 43 (1), 1-10
DOI 10.1016/j.neucli.2012.09.090, PubMed 23290171

Jørum E, Warncke T (2012)
[Treatment of chronic non-malignant pain]
Tidsskr Nor Laegeforen, 132 (22), 2474
DOI 10.4045/tidsskr.12.1246, PubMed 23338018

Kankel J, Obreja O, Kleggetveit IP, Schmidt R, Jørum E, Schmelz M, Namer B (2012)
Differential effects of low dose lidocaine on C-fiber classes in humans
J Pain, 13 (12), 1232-41
DOI 10.1016/j.jpain.2012.09.008, PubMed 23182228

Kleggetveit IP, Namer B, Schmidt R, Helås T, Rückel M, Ørstavik K, Schmelz M, Jørum E (2012)
High spontaneous activity of C-nociceptors in painful polyneuropathy
Pain, 153 (10), 2040-2047
DOI 10.1016/j.pain.2012.05.017, PubMed 22986070

Publications 2011

Schmidt R, Kleggetveit IP, Namer B, Helås T, Obreja O, Schmelz M, Jørum E (2011)
Double spikes to single electrical stimulation correlates to spontaneous activity of nociceptors in painful neuropathy patients
Pain, 153 (2), 391-398
DOI 10.1016/j.pain.2011.10.041, PubMed 22154219

Publications 2010

Jørum E (2010)
Importance of clinical neurophysiological tests in the evaluation of pain: Indispensable in complex pain conditions
Scand J Pain, 1 (4), 177-178
DOI 10.1016/j.sjpain.2010.09.001, PubMed 29913986

Kleggetveit IP, Jørum E (2010)
Large and small fiber dysfunction in peripheral nerve injuries with or without spontaneous pain
J Pain, 11 (12), 1305-10
DOI 10.1016/j.jpain.2010.03.004, PubMed 20488761

Kvarstein G, Jørum E (2010)
[The intern's vein--the patient's nightmare?]
Tidsskr Nor Laegeforen, 130 (12), 1250-1
DOI 10.4045/tidsskr.09.0769, PubMed 20567278

Publications 2009

Koht J, Bjørnarå KA, Jørum E, Tallaksen CM (2009)
Ataxia with vitamin E deficiency in southeast Norway, case report
Acta Neurol Scand Suppl (189), 42-5
DOI 10.1111/j.1600-0404.2009.01214.x, PubMed 19566498

Orstavik K, Jørum E (2009)
Microneurographic findings of relevance to pain in patients with erythromelalgia and patients with diabetic neuropathy
Neurosci Lett, 470 (3), 180-4
DOI 10.1016/j.neulet.2009.05.061, PubMed 19481586

Publications 2008

Jørum E (2008)
Les médecins de Louis XIV: un mémoire sur la médecine du 17ème siècle, la santé et les médecins de Louis XIV ainsi que ses initiatives pour le développement de la médecine
E. Jørum, Oslo, 145 bl.
BIBSYS 082708835

Namer B, Kleggetveit IP, Handwerker H, Schmelz M, Jorum E (2008)
Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury
Pain, 139 (1), 63-72
DOI 10.1016/j.pain.2008.03.007, PubMed 18440147

Publications 2007

Eide PK, Sorteberg W, Meling T, Jörum E, Hald J, Stubhaug A (2007)
From intracranial pressure to intracranial pressure wave-guided intensive care management of a patient with an aneurysmal subarachnoid haemorrhage
Acta Anaesthesiol Scand, 51 (4), 501-4
DOI 10.1111/j.1399-6576.2007.01269.x, PubMed 17378790

Publications 2006

Jørum E, Schmelz M (2006)
Chapter 29 Microneurography in the assessment of neuropathic pain
Handb Clin Neurol, 81, 427-38
DOI 10.1016/S0072-9752(06)80033-3, PubMed 18808851

Jørum E, Ørstavik K, Schmidt R, Namer B, Carr RW, Kvarstein G, Hilliges M, Handwerker H, Torebjörk E, Schmelz M (2006)
Catecholamine-induced excitation of nociceptors in sympathetically maintained pain
Pain, 127 (3), 296-301
DOI 10.1016/j.pain.2006.08.022, PubMed 16997471

Ørstavik K, Namer B, Schmidt R, Schmelz M, Hilliges M, Weidner C, Carr RW, Handwerker H, Jørum E, Torebjörk HE (2006)
Abnormal function of C-fibers in patients with diabetic neuropathy
J Neurosci, 26 (44), 11287-94
DOI 10.1523/JNEUROSCI.2659-06.2006, PubMed 17079656

Ørstavik K, Norheim I, Jørum E (2006)
Pain and small-fiber neuropathy in patients with hypothyroidism
Neurology, 67 (5), 786-91
DOI 10.1212/01.wnl.0000234035.13779.4a, PubMed 16966538

Publications 2005

Jørum E (2005)
[Assessment of neuropathic pain]
Tidsskr Nor Laegeforen, 125 (19), 2652-4
PubMed 16215613

Publications 2004

Cruccu G, Anand P, Attal N, Garcia-Larrea L, Haanpää M, Jørum E, Serra J, Jensen TS (2004)
EFNS guidelines on neuropathic pain assessment
Eur J Neurol, 11 (3), 153-62
DOI 10.1111/j.1468-1331.2004.00791.x, PubMed 15009162

Ørstavik K, Jørum E (2004)
In Diabeteshåndboken, Gyldendal akademisk, Oslo, s. 276-283
BIBSYS 041965361

Ørstavik K, Mørk C, Kvernebo K, Jørum E (2004)
Pain in primary erythromelalgia--a neuropathic component?
Pain, 110 (3), 531-538
DOI 10.1016/j.pain.2004.03.030, PubMed 15288393

Publications 2003

Harbo SO, Jørum E, Roald HE (2003)
Reduction mammaplasty: a prospective study of symptom relief and alterations of skin sensibility
Plast Reconstr Surg, 111 (1), 103-10; discussion 111-2
DOI 10.1097/01.PRS.0000037749.88018.21, PubMed 12496570

Jørum E, Warncke T, Stubhaug A (2003)
Cold allodynia and hyperalgesia in neuropathic pain: the effect of N-methyl-D-aspartate (NMDA) receptor antagonist ketamine--a double-blind, cross-over comparison with alfentanil and placebo
Pain, 101 (3), 229-235
DOI 10.1016/S0304-3959(02)00122-7, PubMed 12583865

Ørstavik K, Weidner C, Schmidt R, Schmelz M, Hilliges M, Jørum E, Handwerker H, Torebjörk E (2003)
Pathological C-fibres in patients with a chronic painful condition
Brain, 126 (Pt 3), 567-78
DOI 10.1093/brain/awg060, PubMed 12566278

Publications 2002

Jorum E (2002)
Assessment of pain and sensory abnormalities in patients with spinal cord injury

Publications 2000

Warncke T, Stubhaug A, Jørum E (2000)
Preinjury treatment with morphine or ketamine inhibits the development of experimentally induced secondary hyperalgesia in man
Pain, 86 (3), 293-303
DOI 10.1016/S0304-3959(00)00260-8, PubMed 10812259

Publications 1997

Warncke T, Jørum E, Stubhaug A (1997)
Local treatment with the N-methyl-D-aspartate receptor antagonist ketamine, inhibit development of secondary hyperalgesia in man by a peripheral action
Neurosci Lett, 227 (1), 1-4
DOI 10.1016/s0304-3940(97)00263-2, PubMed 9178844

Warncke T, Stubhaug A, Jørum E (1997)
Ketamine, an NMDA receptor antagonist, suppresses spatial and temporal properties of burn-induced secondary hyperalgesia in man: a double-blind, cross-over comparison with morphine and placebo
Pain, 72 (1-2), 99-106
DOI 10.1016/s0304-3959(97)00006-7, PubMed 9272793

Publications 1996

Eide PK, Jørum E, Stenehjem AE (1996)
Somatosensory findings in patients with spinal cord injury and central dysaesthesia pain
J Neurol Neurosurg Psychiatry, 60 (4), 411-5
DOI 10.1136/jnnp.60.4.411, PubMed 8774406

Publications 1994

Eide PK, Jørum E, Stubhaug A, Bremnes J, Breivik H (1994)
Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo
Pain, 58 (3), 347-354
DOI 10.1016/0304-3959(94)90129-5, PubMed 7838584

Mackel R, Brink E, Jorum E, Aisen M (1994)
Properties of cutaneous afferents during recovery from Guillain-Barré syndrome
Brain, 117 ( Pt 1), 169-83
DOI 10.1093/brain/117.1.169, PubMed 8149210

Publications 1992

Lundberg LE, Jørum E, Holm E, Torebjörk HE (1992)
Intra-neural electrical stimulation of cutaneous nociceptive fibres in humans: effects of different pulse patterns on magnitude of pain
Acta Physiol Scand, 146 (1), 41-8
DOI 10.1111/j.1748-1716.1992.tb09391.x, PubMed 1442126

Publications 1991

Mackel R, Iriki A, Jorum E, Asanuma H (1991)
Neurons of the pretectal area convey spinal input to the motor thalamus of the cat
Exp Brain Res, 84 (1), 12-24
DOI 10.1007/BF00231758, PubMed 1855554

Publications 1989

Jørum E, Lundberg LE, Torebjörk HE (1989)
Peripheral projections of nociceptive unmyelinated axons in the human peroneal nerve
J Physiol, 416, 291-301
DOI 10.1113/jphysiol.1989.sp017761, PubMed 2607452

Wahren LK, Torebjörk E, Jörum E (1989)
Central suppression of cold-induced C fibre pain by myelinated fibre input
Pain, 38 (3), 313-319
DOI 10.1016/0304-3959(89)90218-2, PubMed 2812842

Publications 1988

Jørum E (1988)
Noradrenergic mechanisms in mediation of stress-induced hyperalgesia in rats
Pain, 32 (3), 349-355
DOI 10.1016/0304-3959(88)90047-4, PubMed 2834686

Jørum E (1988)
The analgesic effect of peripheral nerve stimulation in various tests of nociception in rats
Acta Physiol Scand, 133 (2), 131-8
DOI 10.1111/j.1748-1716.1988.tb08392.x, PubMed 3265842

Jørum E (1988)
Analgesia or hyperalgesia following stress correlates with emotional behavior in rats
Pain, 32 (3), 341-348
DOI 10.1016/0304-3959(88)90046-2, PubMed 3362568

Jørum E (1988)
Central control of pain sensitivity in rats
[E. Jørum], Oslo, 1 b. (flere pag.)
BIBSYS 884096025

Jørum E, Shyu BC (1988)
Analgesia by low-frequency nerve stimulation mediated by low-threshold afferents in rats
Pain, 32 (3), 357-366
DOI 10.1016/0304-3959(88)90048-6, PubMed 3362569

Publications 1987

Jørum E, Shyu BC (1987)
Course and mode of action of descending system conveying nucleus raphe magnus induced inhibition of flexion reflex in rats
Acta Physiol Scand, 131 (4), 489-97
DOI 10.1111/j.1748-1716.1987.tb08268.x, PubMed 2964771

Publications 1979

Acupunct. Electro-Ther. Res., 4 (3-4), 221-234

Page visits: 7587