Previous publications from the Center

 

2017

Rydning SL, Backe PH, Sousa MML, Iqbal Z, Øye AM, Sheng Y, Yang M, Lin X, Slupphaug G, Nordenmark TH, Vigeland MD, Bjørås M, Tallaksen CM, Selmer KK.
Novel UCHL1 mutations reveal new insights into ubiquitin processing. Hum Mol Genet. 2017 Mar 15;26(6):1217-1218

Morland C, Andersson KA, Haugen ØP, Hadzic A, Kleppa L, Gille A, Rinholm JE, Palibrk V, Diget EH, Kennedy LH, Stølen T, Hennestad E, Moldestad O, Cai Y, Puchades M, Offermanns S, Vervaeke K, Bjørås M, Wisløff U, Storm-Mathisen J, Bergersen LH.
Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1. Nat Commun. 2017 May 23;8:15557

Bosshard M, Aprigliano R, Gattiker C, Palibrk V, Markkanen E, Hoff Backe P, Pellegrino S, Raymond FL, Froyen G, Altmeyer M, Bjørås M, Dianov GL, van Loon B.
Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability. Sci Rep. 2017 Nov 8;7(1):15050

Kosik-Kozioł A, Costantini M, Bolek T, Szöke K, Barbetta A, Brinchmann JE, Święszkowski W.
PLA short sub-micron fiber reinforcement of 3D bioprinted alginate constructs for cartilage regeneration. Biofabrication. 2017 Nov 14;9(4):044105. doi: 10.1088/1758-5090/aa90d7

Szöke K, Danakova J, Bugzo M, Amler E, Brinchmann JE, Østrup E.
The effect of medium composition on deposition of collagen type I and expression of osteogenic genes in mesenchymal stem cells derived from human adipose tissue and bone marrow. Proc Biochem 2017;59,321-28.

Wollert KC, Meyer GP, Müller-Ehmsen J, Tschöpe C, Bonarjee V, Larsen AI, May AE, Empen K, Chorianopoulos E, Tebbe U, Waltenberger J, Mahrholdt H, Ritter B, Pirr J, Fischer D, Korf-Klingebiel M, Arseniev L, Heuft HG, Brinchmann JE, Messinger D, Hertenstein B, Ganser A, Katus HA, Felix SB, Gawaz MP, Dickstein K, Schultheiss HP, Ladage D, Greulich S, Bauersachs J.Eur Heart J. Intracoronary autologous bone marrow cell transfer after myocardial infarction: the BOOST-2 randomised placebo-controlled clinical trial. 2017 Oct 14;38(39):2936-2943. doi: 10.1093/eurheartj/ehx188

Behnan J, Stangeland B, Hosainey SAM, Joel M, Olsen TK, Micci F, Glover JC, Isakson P, Brinchmann JE. Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency. Oncogene. 2017 Jan 26;36(4):570-584

Karlsen TA, Jakobsen RB, Brinchmann JE. Early molecular events during in vitro chondrogenesis. In The Biology and Therapeutic Application of Mesenchymal Cells (ed K. Atkinson), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118907474.ch14

Paulsen J, Sekelja M, Oldenburg AR, Barateau A, Briand N, Delbarre E, Shah, A, Sørensen AL, Vigouroux C, Buendia B, Collas P. 2017. Chrom3D: three-dimensional genome modeling from Hi-C and nuclear lamin-genome contacts. Genome Biol. 18, 21-29

Guénantin AC, Briand N, Capel E, Dumont F, Morichon R, Provost C, Stillitano F, Jeziorowska D, Siffroi JP, Hajjar RJ, Fève B, Hulot JS, Collas P, Capeau J, Vigouroux C. 2017. Functional human beige adipocytes from induced pluripotent stem cells. Diabetes 66, 1470-1478

Delbarre, E, Ivanauskiene K, Spirkoski J, Shah A, Vekterud K, Moskaug JØ, Bøe SO, Wong L, Küntziger T, Collas P. 2017. PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX. Genome Res. 27, 913-921

López-Soop G, Rønningen T, Rogala A, Richartz N, Blomhoff HK, Thiede B, Collas P, Küntziger T. 2017. AKAP95 interacts with nucleoporin TPR in mitosis and is important for the spindle assembly checkpoint. Cell Cycle 16, 947-956

Oldenburg AR, Briand N, Sørensen AL, Cahyani I, Shah A, Moskaug JØ, Collas P 2017. A lipodystrophy-causing lamin A mutant alters conformation and epigenetic regulation of the anti-adipogenic MIR335 locus. J Cell Biol. 216, 2731-2743

Garcia-Nieto PE, Schwartz E, King DA, Paulsen J, Collas P, Herrera RE, Morrison AJ. 2017.
Carcinogen susceptibility is regulated by genome architecture and dictates cancer mutagenenesis. EMBO J. 36, 2839-2843

Meier M, Grant J, Dowdle A, Thomas A, Gerton J, Collas P, O'Sullivan JM, Horsfield JA. 2017.
Cohesin facilitates zygotic genome activation in zebrafish. Development. doi: 10.1242/dev.156521

Züchner M, Kondratskaya E, Sylte CB, Glover JC, Boulland JL. Rapid recovery and altered neurochemical dependence of locomotor central pattern generation following lumbar neonatal spinal cord injury. J Physiol. 2018 Jan 15;596(2):281-303. doi: 10.1113/JP274484. Epub 2017 Dec 3.

Chagnaud BP, Engelmann J, Fritzsch B, Glover JC, Straka H. Sensing External and Self-Motion with Hair Cells: A Comparison of the Lateral Line and Vestibular Systems from a Developmental and Evolutionary Perspective.Brain Behav Evol. 2017;90(2):98-116. doi: 10.1159/000456646. Epub 2017 Oct 9.

Fritzsch B, Elliott KL, Glover JC. Gaskell revisited: new insights into spinal autonomics necessitate a revised motor neuron nomenclature. Cell Tissue Res. 2017 Nov;370(2):195-209. doi: 10.1007/s00441-017-2676-y. Epub 2017 Aug 31. Review.

Chawla RS, Züchner M, Mastrangelopoulou M, Lambert FM, Glover JC, Boulland JL.
Cellular reactions and compensatory tissue re-organization during spontaneous recovery after spinal cord injury in neonatal mice. Dev Neurobiol. 2017 Sep;77(8):928-946. doi: 10.1002/dneu.22479. Epub 2017 Feb 17.

Tang C, Klukovich R, Peng H, Wang Z, Yu T, Zhang Y, Zheng H, Klungland A, Yan W. ALKBH5-dependent m6A demethylation controls splicing and stability of long 3'-UTR mRNAs in male germ cells. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E325-E333

Pawar T, Bjørås M, Klungland A, Eide L. Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA. Mitochondrion. 2017 Sep 8. pii: S1567-7249(17)30208-8

Seifermann M, Ulges A, Bopp T, Melcea S, Schäfer A, Oka S, Nakabeppu Y, Klungland A, Niehrs C, Epe B.
Role of the DNA repair glycosylase OGG1 in the activation of murine splenocytes. DNA Repair (Amst). 2017 Oct;58:13-20.

Jordan JJ, Chhim S, Margulies CM, Allocca M, Bronson RT, Klungland A, Samson LD, Fu D. ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage. Cell Death Dis. 2017 Jul 20;8(7):e2947.

Rolseth V, Luna L, Olsen AK, Suganthan R, Scheffler K, Neurauter CG, Esbensen Y, Kuśnierczyk A, Hildrestrand GA, Graupner A, Andersen JM, Slupphaug G, Klungland A, Nilsen H, Bjørås M. No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice. Sci Rep. 2017 Jun 29;7(1):4384

Landfors M, Johansen J, Aronsen JM, Vågbø CB, Doré LC, He C, Sjaastad I, Sætrom P, Fedorcsák P, Dahl JA, Aanes H, Fußer M, Klungland A.
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation. Cell Discov. 2017 May 9;3:17013.

Aas A, Isakson P, Bindesbøll C, Alemu EA, Klungland A, Simonsen A.
Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy. PLoS One. 2017 Mar 13;12(3):e0168182.

Kalikstad B, Kultima HG, Andersstuen TK, Klungland A, Isaksson A. Gene expression profiles on preterm infants on continuous long‑term oxygen therapy suggest reduced oxidative stress‑dependent signaling during hypoxia. Mol Med Rep. 2017 Apr;15(4):1513-1526

Chymkowitch P, Nguéa P A, Aanes H, Robertson J, Klungland A, Enserink JM. TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity.Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1039-1044.

Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JDS, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, Brorson SH, Zhang L, Gullestad L, Louch WE, Iversen PO, Østlie I, Klungland A, Christensen G, Sjaastad I, Sætrom P, Yndestad A, Aukrust P, Bjørås M, Finsen AV.
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell Rep. 2017 Jan 3;18(1):82-92

Klungland A, Robertson AB. Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine. Free Radic Biol Med 2017 Jun;107:62-68.

Arjamaa O, Aaltonen V, Piippo N, Csont T, Petrovski G, Kaarniranta K, Kauppinen A (2017)
Hypoxia and inflammation in the release of VEGF and interleukins from human retinal pigment epithelial cells. Graefes Arch Clin Exp Ophthalmol, 255 (9), 1757-1762  PubMed 28631245 WOS 000407587600010 Cristin 1501797 FullText (Details)

Glatz W, Steinwender G, Tarmann L, Malle EM, Schörkhuber M, Wackernagel W, Petrovski G, Wedrich A, Ivastinovic D (2017) Vitreous hyper-reflective dots in pseudophakic cystoid macular edema assessed with optical coherence tomography. PLoS One, 12 (12), e0189194  PubMed 29244855 WOS 000418184700020 FullText (Details)

Hongisto H, Jylhä A, Nättinen J, Rieck J, Ilmarinen T, Veréb Z, Aapola U, Beuerman R, Petrovski G, Uusitalo H, Skottman H (2017) Comparative proteomic analysis of human embryonic stem cell-derived and primary human retinal pigment epithelium. Sci Rep, 7 (1), 6016 PubMed 28729539 WOS 000405907800070 Cristin 1503863 FullText (Details)

Hytti M, Andjelic S, Josifovska N, Piippo N, Korhonen E, Hawlina M, Kaarniranta K, Nevalainen TJ, Petrovski G, Parkkari T, Kauppinen A (2017)  CB2 receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells. Sci Rep, 7 (1), 16169 PubMed 29170454 WOS 000416129500004 Cristin 1528818 FullText (Details)

Hytti M, Szabó D, Piippo N, Korhonen E, Honkakoski P, Kaarniranta K, Petrovski G, Kauppinen A (2017) Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cells. J Nutr Biochem, 42, 37-42
PubMed 28113103 WOS 000398010600005 Cristin 1473840 FullText (Details)

Johnsen EO, Frøen RC, Olstad OK, Nicolaissen B, Petrovski G, Moe MC, Noer A (2017)
Proliferative Cells Isolated from the Adult Human Peripheral Retina only Transiently Upregulate Key Retinal Markers upon Induced Differentiation. Curr Eye Res, 1-10 (in press)  PubMed 29161152 FullText (Details)

Josifovska N, Szabó DJ, Nagymihály R, Veréb Z, Facskó A, Eriksen K, Moe MC, Petrovski G (2017) Cultivation and characterization of pterygium as an ex vivo study model for disease and therapy. Cont Lens Anterior Eye, 40 (5), 283-292
PubMed 28550976 WOS 000410658600003 FullText (Details)

Jørstad ØK, Faber RT, Moe MC (2017) Two-year functional and anatomical results after converting treatment resistant eyes with exudative age-related macular degeneration to aflibercept in accordance with a treat and extend protocol. Acta Ophthalmol, 95 (5), 460-463  PubMed 28556485 WOS 000405388500022 Cristin 1501447 FullText (Details)

Kaarniranta K, Petrovski G, Kauppinen A (2017)
The Nobel Prized cellular target autophagy in eye diseases. Acta Ophthalmol, 95 (4), 335-336
PubMed 28603953 WOS 000403361300013 FullText (Details)

Lytvynchuk L, Sergienko A, Savytska I, Albert R, Glittenberg C, Binder S, Petrovski G (2017)  Comparative cyto-histological study of needle tip aspirates and entry sites after intravitreal injection using different needle types. PLoS One, 12 (7), e0174467
PubMed 28692684 WOS 000405544800001 Cristin 1503675 FullText (Details)

Márkus B, Pató Z, Sarang Z, Albert R, Tőzsér J, Petrovski G, Csősz É (2017) The proteomic profile of a mouse model of proliferative vitreoretinopathy. FEBS Open Bio, 7 (8), 1166-1177  PubMed 28781956 WOS 000406682900010 Cristin 1501500 FullText (Details)

Nagymihály R, Veréb Z, Albert R, Sidney L, Dua H, Hopkinson A, Petrovski G (2017)
Cultivation and characterisation of the surface markers and carbohydrate profile of human corneal endothelial cells. Clin Exp Ophthalmol, 45 (5), 509-519  PubMed 28032398 WOS 000406911300011 FullText (Details)

Nagymihály R, Veréb Z, Facskó A, Moe MC, Petrovski G (2017) Effect of Isolation Technique and Location on the Phenotype of Human Corneal Stroma-Derived Cells. Stem Cells Int, 2017, 9275248 PubMed 29213290 WOS 000413828600001 FullText (Details)

Ness C, Garred Ø, Eide NA, Kumar T, Olstad OK, Bærland TP, Petrovski G, Moe MC, Noer A (2017) Multicellular tumor spheroids of human uveal melanoma induce genes associated with anoikis resistance, lipogenesis, and SSXs Mol Vis, 23, 680-694
PubMed 29033534 WOS 000412367800001 FullText (Details)

Petrovski G, Kaarniranta K, Petrovič D (2017) Oxidative Stress, Epigenetics, Environment, and Epidemiology of Diabetic Retinopathy. J Diabetes Res, 2017, 6419357  PubMed 28321416 WOS 000396146600001 FullText (Details)

Szabó DJ, Nagymihály R, Veréb Z, Josifovska N, Noer A, Liskova P, Facskó A, Moe MC, Petrovski G (2017) Ex vivo 3D human corneal stroma model for Schnyder corneal dystrophy - role of autophagy in its pathogenesis and resolution. Histol Histopathol, 11928 (in press)
PubMed 28872183 FullText (Details)

Siller R and Sullivan GJ^*. Simple and rapid screen for human pluripotent stem cell endoderm differentiation potential. Current Protocols in Stem Cell Biology, 43, 1G.7.1–1G.7.23.doi: 10.1002/cpsc.36. (*corresponding author).

Rutkovskiy A, Malashicheva A, Sullivan GJ^*, Bogdanova M, Kostareva A, Stensløkken KO, Fianne A, Vaage J. Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification. Journal of the American Heart Association. 2017: 14;6(9) pii: e006339. doi: 10.1161/JAHA.117.006339.(*co-corresponding author).

Scarfe L, Brillant N, Kumar JD, Ali N, Alrumayh A, Amali M, Barbellion S, Jones V, Niemeijer M, Potdevin S, Roussignol G, Vaganov A, Barbaric I, Barrow M, Burton NC, Connell J, Dazzi F, Edsbagge J, French NS, Holder J, Hutchinson C, Jones DR, Kalber T, Lovatt C, Lythgoe MF, Patel S, Patrick PS, Piner J, Reinhardt J, Ricci E, Sidaway J, Stacey GN, Starkey Lewis PJ, Sullivan G, Taylor A, Wilm B, Poptani H, Murray P, Goldring CEP, Park BK. Pre-clinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies. Nature Regenerative Medicine. 2017: (2017)2:28; doi:10.1038/s41536-017-0029-9.

Siller R, Greenhough S, Mathipati S, Si-Tayeb K^* and Sullivan GJ^*. Future challenges in the generation of hepatocyte like cells from human pluripotent stem cells. Current Pathobiology Reports. 2017:5:(3):301-314. (*co-corresponding author).

Siller R, Dufour E, Wilmut I, Jung Y-W, Park IH and Sullivan GJ^*. Development of an inducible platform for intercellular protein delivery. International Journal of Pharmaceutics. 2017: http://dx.doi.org/10.1016/j.ijpharm.2017.02.067. (*corresponding author).

Gamal W, Treskes P, Chesne CG, Samuel K, Sullivan GJ, Siller R, Srsen V, Underwood I, Smith S, Hayes PC, Plevris JN, Bagnaninchi PO and Nelson LJ. Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver. Scientific Reports. 2017:DOI: 10.1038/srep37541.

Klungland A, Dahl JA, Greggains G, Fedorcsak P, Filipczyk A.
Reversible RNA modifications in meiosis and pluripotency. 18 |VOL.14 NO.1 | Jan 2017 | NATURE METHODS

Thomas Fleischer, Xavier Tekpli, Anthony Mathelier, Shixiong Wang, Daniel Nebdal, Hari P. Dhakal, Kristine Kleivi Sahlberg, Ellen Schlichting, Oslo Breast Cancer Research Consortium (OSBREAC), Anne-Lise Børresen-Dale, Elin Borgen, Bjørn Naume,

Ragnhild Eskeland, Arnoldo Frigessi, Jörg Tost, Antoni Hurtado, Vessela N. Kristensen.
Major gene regulatory networks explained by DNA methylation at enhancers distinguish ER positive and ER negative breast cancer lineages. Nature Communications. 2017 Nov 9;8(1):1379. doi: 10.1038/s41467-017-00510-x.

Boris Simovski; Daniel Vodák; Sveinung Sveinung; Diana Domanska; Abdulrahman Azab; Lars Holden; Marit Holden; Ivar Grytten; Knut Dagestad Rand; Finn Drabløs; Morten Johansen; Antonio Mora; Christin Lund-Andersen; Bastian Fromm; Ragnhild Eskeland; Odd Stokke Gabrielsen; Sigve Nakken; Mads Bengtsen; Alexander Johan Nederbragt; Hildur Sif Thorarensen; Johannes Andreas Akse; Ingrid Glad; Eivind Hovig; Geir Kjetil Sandve.
GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome. GigaScience. 2017 Apr 27. doi: 10.1093/gigascience/gix032.

Bettina Maria Fuglerud, Roza Berhanu Lemma, Pimthanya Wanichawan, Arvind Sundaram, Marit Ledsaak, Ragnhild Eskeland and Odd Stokke Gabrielsen
The interaction of c-Myb with histone tails is disrupted by the hematopoietic mutant D152V - evidence for altered pioneer function. Nucleic Acids Research. Nucleic Acids Res. 2017 May 2. doi: 10.1093/nar/gkx364. [Epub ahead of print]

Marie MacLennan, Marta García-Cañadas, Judith Reichmann, Elena Khazina, Carmen Salvador-Palomeque, Abigail R. Mann, Paula Peressini, Laura Sanchez, Christopher J. Playfoot, David Read, Chao-Chun Hung, Ragnhild Eskeland, Richard R. Meehan, Oliver Weichenrieder, Jose Luis García-Pérez, Ian R. Adams.
The Ubiquitin-Proteasome System Protects The Mammalian Germline From L1 Retrotransposons. eLife 2017 Aug 14;6. pii: e26152. doi: 10.7554/eLife.26152.

Abadpour S, Gopel SO, Schive SW, Korsgren O, Foss A, Scholz H.
Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis. Sci Rep. 2017;7(1):1575.

Hals I, Ohki T, Singh R, Ma Z, Björklund A, Balasuriya C, Scholz H, Grill V.Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates. Physiol Rep. 2017;5(19).

Li X, Zhong Y, Lu J, Axcrona K, Eide L, Syljuåsen RG, Peng Q, Wang J, Zhang H, Goscinski MA, Kvalheim G, Nesland JM, Suo Z. Correction: MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features.
Oncotarget. 2017 Jan 24;8(4):7208-7213. doi: 10.18632/oncotarget.14800. No abstract available.

Wang MY, Nestvold J, Rekdal Ø, Kvalheim G, Fodstad Ø. A novel rat fibrosarcoma cell line from transformed bone marrow-derived mesenchymal stem cells with maintained in vitro and in vivo stemness properties. Exp Cell Res. 2017 Mar 15;352(2):218-224. doi: 10.1016/j.yexcr.2017.02.005. Epub 2017 Feb 9.

Inderberg EM, Wälchli S, Myhre MR, Trachsel S, Almåsbak H, Kvalheim G, Gaudernack G.
T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth.
Oncoimmunology. 2017 Mar 17;6(4):e1302631. doi: 10.1080/2162402X.2017.1302631. eCollection 2017.

Li X, Lu J, Kan Q, Li X, Fan Q, Li Y, Huang R, Slipicevic A, Dong HP, Eide L, Wang J, Zhang H, Berge V, Goscinski MA, Kvalheim G, Nesland JM, Suo Z. Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells. Sci Rep. 2017 Jul 11;7(1):5081. doi: 10.1038/s41598-017-05086-6.

Li X, Grigalavicius M, Li Y, Li X, Zhong Y, Huang R, Yu D, Berge V, Goscinski MA, Kvalheim G, Nesland JM, Suo Z.
MtDNA depletion influences the transition of CD44 subtypes in human prostate cancer DU145 cells. Tumour Biol. 2017 Aug;39(8):1010428317713671. doi: 10.1177/1010428317713671.

Walseng E, Köksal H, Sektioglu IM, Fåne A, Skorstad G, Kvalheim G, Gaudernack G, Inderberg EM, Wälchli S.
A TCR-based Chimeric Antigen Receptor. Sci Rep. 2017 Sep 6;7(1):10713. doi: 10.1038/s41598-017-11126-y.

Nestvold J, Wang MY, Camilio KA, Zinöcker S, Tjelle TE, Lindberg A, Haug BE, Kvalheim G, Sveinbjørnsson B, Rekdal Ø. Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model. Oncoimmunology. 2017 Jun 16;6(8):e1338236. doi: 10.1080/2162402X.2017.1338236. eCollection 2017.

Eide N, Faye RS, Høifødt HK, Sandvik L, Qvale GA, Faber R, Jebsen P, Kvalheim G, Fodstad Ø. The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy. Pathol Oncol Res. 2017 Nov 2. doi: 10.1007/s12253-017-0355-7.

Inderberg EM, Mensali N, Oksvold MP, Fallang LE, Fåne A, Skorstad G, Stenvik GE, Progida C, Bakke O, Kvalheim G, Myklebust JH, Wälchli S. Human c-SRC kinase (CSK) overexpression makes T cells dummy. Cancer Immunol Immunother. 2017 Dec 16. doi: 10.1007/s00262-017-2105-9. [Epub ahead of print]

Schive SW, Foss A, Sahraoui A, Kloster-Jensen K, Hafsahl G, Kvalheim G, Lundgren T, von Zur-Mühlen B, Felldin M, Rafael E, Lempinen M, Korsgren O, Jenssen TG, Mishra V, Scholz H.
Cost and clinical outcome of islet transplantation in Norway 2010-2015. Clin Transplant. 2017;31(1).

Schive SW, Mirlashari MR, Hasvold G, Wang M, Josefsen D, Gullestad HP, Korsgren O, Foss A, Kvalheim G, Scholz H. Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo. Cell Med. 2017;9(3):103-16.

Schuetz C, Anazawa T, Cross SE, Labriola L, Meier RPH, Redfield RR 3rd, Scholz H, Stock PG, Zammit NW; IPITA YIC Young Investigator Committee. ss cell replacement therapy: the next 10 years. Transplantation. 2017.

Vethe H, Bjorlykke Y, Ghila LM, Paulo JA, Scholz H, Gygi SP, et al. Probing the missing mature beta-cell proteomic landscape in differentiating patient iPSC-derived cells. Sci Rep. 2017;7(1):4780.

 

2016

Jalland C, Scheffler K, Benestad S, Moldal T, Ersdal C, Gunnes G, Suganthan R, Bjørås M, Tranulis M. Neil3 induced neurogenesis protects against prion disease during the clinical phase. Sci Reports. 6:37844

Dahl JA, Jung I, Aanes H, Greggains GD, Mana A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A. Broad histone H3K4me3 domains in mouse oocytes modulate maternal to zygotic transition.
Nature, Sep 14;537(7621):548-552

Palibrk V, Suganthan R, Scheffler K, Wang W, Bjørås M# and Bøe SO. PML# regulates neuroprotective innate immunity and neuroblast commitment in a hypoxia ischemic encephalopathy model. Cell Death and Disease. 2016. 7(7):e2320

Karlsen TA, de Souza G, Ødegaard B, Engebretsen L, Brinchmann JE.
MicroRNA-140 inhibits inflammation and stimulates chondrogenesis in a model of IL1β-induced osteoarthritis. Mol Ther Nucleic Acids. 2016 Oct 11;5(10) :e373. doi: 10.1038/mtna.2016.64.

Costantini M, Idaszek J, Szöke K, Jaroszewicz J, Dentini M, Barbetta A, Brinchmann JE, Święszkowski W. 3D bioprinting of BM-MSCs-loaded ECM biomimetic hydrogels for in vitro neocartilage formation. Biofabrication. 2016 Jul 19;8(3):035002. doi: 10.1088/1758-5090/8/3/035002.

Behnan J, Stangeland B, Langella T, Finocchiaro G, Murrell W, Brinchmann JE. Ultrasonic Surgical Aspirate is a Reliable Source For Culturing Glioblastoma Stem Cells. Sci Rep. 2016 Sep 8;6:32788. doi: 10.1038/srep32788.

Behnan J, Stangeland B, Hosainey SA, Joel M, Olsen TK, Micci F, Glover JC, Isakson P, Brinchmann JE. Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency. Oncogene. 2016 Jun 27. doi: 10.1038/onc.2016.230.

Aae TF, Randsborg PH, Breen AB, Visnes H, Vindfeld S, Sivertsen EA, Løken S, Brinchmann J, Hanvold HA, Årøen A. Norwegican Cartilage Project - a study protocol for a double-blinded randomized controlled trial comparing arthroscopic microfracture with arthroscopic debridement in focal cartilage defects in the knee. BMC Musculoskelet Disord. 2016 Jul 16;17:292. doi: 10.1186/s12891-016-1156-y.

Randsborg PH, Brinchmann J, Løken S, Hanvold HA, Aae TF, Årøen A. Focal cartilage defects in the knee - a randomized controlled trial comparing autologous chondrocyte implantation with arthroscopic debridement. BMC Musculoskelet Disord. 2016 Mar 8;17:117. doi: 10.1186/s12891-016-0969-z.

Szöke K, Reinisch A, Østrup E, Reinholt FP, Brinchmann JE. Autologous cell sources in therapeutic vasculogenesis: In vitro and in vivo comparison of endothelial colony-forming cells from peripheral blood and endothelial cells isolated from adipose tissue. Cytotherapy. 2016 Feb;18(2):242-52. doi: 10.1016/j.jcyt.2015.10.009.

Karlsen TA, Jakobsen RB, Brinchmann JE. Early molecular events during in vitro chondrogenesis. In The Biology and Therapeutic Application of Mesenchymal Cells (ed K. Atkinson), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118907474.ch14

Legartová S, Sehnalová P, Malyšková B, Küntziger T, Collas P, Cmarko D, Raška I, Sorokin DV, Kozubek S, Bártová E J, Localized Movement and Levels of 53BP1 Protein Are Changed by γ-irradiation in PML Deficient Cells. Cell Biochem. 2016 Nov;117(11):2583-96. doi: 10.1002/jcb.25551. PMID:27526954

Lindstad T, Qu S, Sikkeland J, Jin Y, Kristian A, Mælandsmo GM, Collas P, Saatcioglu F. STAMP2 is required for human adipose-derived stem cell differentiation and adipocyte-facilitated prostate cancer growth in vivo. Oncotarget. 2016 Aug 9. doi: 10.18632/oncotarget.11131. PMID:27517316

Vanhove J, Pistoni M, Welters M, Eggermont K, Vanslembrouck V, Helsen N, Boon R, Najimi M, Sokal E, Collas P, Voncken JW, Verfaillie CM. H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro..Stem Cell Reports. 2016 Aug 9;7(2):192-206. doi: 10.1016/j.stemcr.2016.06.013. PMID:27477635

Oldenburg AR, Collas P. Mapping Nuclear Lamin-Genome Interactions by Chromatin Immunoprecipitation of Nuclear Lamins. Methods Mol Biol. 2016;1411:315-24. doi: 10.1007/978-1-4939-3530-7_20. PMID: 27147051

Sekelja M, Paulsen J, Collas P. 4D nucleomes in single cells: what can computational modeling reveal about spatial chromatin conformation? Genome Biol. 2016 Apr 7;17:54. doi: 10.1186/s13059-016-0923-2. Review. PMID:27052789

Buemo CP, Gambini A, Moro LN, Hiriart MI, Fernández-Martín R, Collas P, Salamone DF. Embryo Aggregation in Pig Improves Cloning Efficiency and Embryo Quality. PLoS One. 2016 Feb 19;11(2):e0146390. doi:10.1371/journal.pone.0146390. PMID:26894831

Marstad A, Landsverk OJ, Strømme O, Otterlei M, Collas P, Sundan A, Brede G. A-kinase anchoring protein AKAP95 is a novel regulator of ribosomal RNA synthesis. FEBS J. 2016 Feb;283(4):757-70. doi: 10.1111/febs.13630. PMID: 6683827

Chawla RS, Züchner M, Mastrangelopoulou M, Lambert FM, Glover JC, Boulland JL. Cellular reactions and compensatory tissue re-organization during spontaneous recovery after spinal cord injury in neonatal mice. Dev Neurobiol. 2016 Dec 29. doi: 10.1002/dneu.22479. PMID: 28033684

Züchner M, Glover JC, Boulland JL.
A Neonatal Mouse Spinal Cord Compression Injury Model.
J Vis Exp. 2016 Mar 27;(109):e53498. doi: 10.3791/53498. PMID: 27078037

Bjørnstad S, Samara A, Erichsen A, Paulsen RE, Glover JC, Roald B.Hampered Lung Maturation in Methimazole-Induced Hypothyroidism in Fetal Chicken: Morphological and Molecular Correlates to Human Fetal Development. Neonatology. 2016;110(2):83-92. doi: 10.1159/000444656. PMID: 27070722

Falk A, Heine VM, Harwood AJ, Sullivan PF, Peitz M, Brüstle O, Shen S, Sun YM, Glover JC, Posthuma D, Djurovic S. Modeling psychiatric disorders: from genomic findings to cellular phenotypes.Mol Psychiatry. 2016 Sep;21(9):1321. doi: 10.1038/mp.2016.100. PMID: 27324182

Lambert FM, Bras H, Cardoit L, Vinay L, Coulon P, Glover JC.
Early postnatal maturation in vestibulospinal pathways involved in neck and forelimb motor control.
Dev Neurobiol. 2016 Oct;76(10):1061-77. doi: 10.1002/dneu.22375. PMID:26724676

Sivertsen MS, Perreault MC, Glover JC.
Pontine reticulospinal projections in the neonatal mouse: Internal organization and axon trajectories. J Comp Neurol. 2016 Apr 15;524(6):1270-91. doi: 10.1002/cne.23904. PMID:26400815

Liu F, Clark W, Luo G, Wang X, Fu Y, Wei J, Wang X, Hao Z, Dai Q, Zheng G, Ma H, Han D, Evans M, Klungland A, Pan T, He C.
ALKBH1-Mediated tRNA Demethylation Regulates Translation
Cell. 2016 Dec 15;167(7):1897. doi: 10.1016/j.cell.2016.11.045. PMID: 27984735

Klungland A, Robertson AB.
Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine.
Free Radic Biol Med. 2016 Nov 24. pii: S0891-5849(16)31072-3. doi: 10.1016/j.freeradbiomed.2016.11.038. PMID: 27890639

Vindedal GF, Thoren AE, Jensen V, Klungland A, Zhang Y, Holtzman MJ, Ottersen OP, Nagelhus EA. Removal of aquaporin-4 from glial and ependymal membranes causes brain water accumulation. Mol Cell Neurosci. 2016 Dec;77:47-52. doi: 10.1016/j.mcn.2016.10.004. PMID: 27751903

Liu F, Clark W, Luo G, Wang X, Fu Y, Wei J, Wang X, Hao Z, Dai Q, Zheng G, Ma H, Han D, Evans M, Klungland A, Pan T, He C.
ALKBH1-Mediated tRNA Demethylation Regulates Translation. Cell. 2016 Oct 20;167(3):816-828.e16. doi: 10.1016/j.cell.2016.09.038. PMID: 27745969

Lauritzen KH, Hasan-Olive MM, Regnell CE, Kleppa L, Scheibye-Knudsen M, Gjedde A, Klungland A, Bohr VA, Storm-Mathisen J, Bergersen LH.
A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain. Neurobiol Aging. 2016 Dec;48:34-47. doi: 10.1016/j.neurobiolaging.2016.08.005. PMID: 27639119

Møllersen L, Moldestad O, Rowe AD, Bjølgerud A, Holm I, Tveterås L, Klungland A, Retterstøl L. Effects of Anthocyanins on CAG Repeat Instability and Behaviour in Huntington's Disease R6/1 Mice.
PLoS Curr. 2016 Jul 5;8. pii: ecurrents.hd.58d04209ab6d5de0844db7ef5628ff67. doi: 10.1371/currents.hd.58d04209ab6d5de0844db7ef5628ff67. PMID: 27540492

A Alemu E, He C, Klungland A.
ALKBHs-facilitated RNA modifications and de-modifications. DNA Repair (Amst). 2016 Aug;44:87-91. doi: 10.1016/j.dnarep.2016.05.026. Review. PMID: 27237585

Weber AR, Krawczyk C, Robertson AB, Kuśnierczyk A, Vågbø CB, Schuermann D, Klungland A, Schär P.Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
Nat Commun. 2016 Mar 2;7:10806. doi: 10.1038/ncomms10806. PMID: 26932196

Landfors M, Nakken S, Fusser M, Dahl JA, Klungland A, Fedorcsak P.
Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies an infertility-associated variant and two missense mutations. Fertil Steril. 2016 May;105(5):1170-1179.e5. doi: 10.1016/j.fertnstert.2016.01.002. PMID: 26820768

Ougland R, Jonson I, Moen MN, Nesse G, Asker G, Klungland A, Larsen E.
Role of ALKBH1 in the Core Transcriptional Network of Embryonic Stem Cells.
Cell Physiol Biochem. 2016;38(1):173-84. doi: 10.1159/000438619. PMID: 26765775

Klungland A, Yang YG. Endogenous DNA Damage and Repair Enzymes: -A short summary of the scientific achievements of Tomas Lindahl, Nobel Laureate in Chemistry 2015. Genomics Proteomics Bioinformatics. 2016 Jun;14(3):122-5. doi: 10.1016/j.gpb.2015.11.001. PMID: 26689322

Mi S, Klungland A, Yang YG.
Base-excision repair and beyond --A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015. Sci China Life Sci. 2016 Jan;59(1):89-92. doi: 10.1007/s11427-015-4983-4. PMID: 26676642

Kyte JA, Gaudernack G, Faane A, Lislerud K, Inderberg EM, Brunsvig P, Aamdal S, Kvalheim G, Wälchli S, Pule M.
T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy. Oncoimmunology. 2016 Oct 24;5(12):e1249090. doi: 10.1080/2162402X.2016.1249090. PMID: 28123886

Kyte JA, Aamdal S, Dueland S, Sæbøe-Larsen S, Inderberg EM, Madsbu UE, Skovlund E, Gaudernack G, Kvalheim G.
Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells. Oncoimmunology. 2016 Oct 18;5(11):e1232237. doi: 10.1080/2162402X.2016.1232237. PMID: 27999747

Midttun Ø, McCann A, Aarseth O, Krokeide M, Kvalheim G, Meyer K, Ueland PM. Combined Measurement of 6 Fat-Soluble Vitamins and 26 Water-Soluble Functional Vitamin Markers and Amino Acids in 50 μL of Serum or Plasma by High-Throughput Mass Spectrometry. Anal Chem. 2016 Nov 1;88(21):10427-10436. PMID: 27715010

Li X, Zhong Y, Lu J, Axcrona K, Eide L, Syljuåsen RG, Peng Q, Wang J, Zhang H, Goscinski MA, Kvalheim G, Nesland JM, Suo Z.
MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features. Oncotarget. 2016 Jun 28;7(26):40297-40313. doi: 10.18632/oncotarget.9610. Erratum in: Oncotarget. 2017 Jan 24;8(4):7208-7213. PMID: 27248169

Sioud M, Nyakas M, Sæbøe-Larssen S, Mobergslien A, Aamdal S, Kvalheim G. Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine.
Case Rep Med. 2016;2016:9639585. doi: 10.1155/2016/9639585. PMID: 27504122

Fayzullin A, Tuvnes FA, Skjellegrind HK, Behnan J, Mughal AA, Langmoen IA, Vik-Mo EO. Time-lapse phenotyping of invasive glioma cells ex vivo reveals subtype-specific movement patterns guided by tumor core signaling. Exp Cell Res. 2016 Dec 10;349(2):199-213. doi: 10.1016/j.yexcr.2016.08.001. PubMed PMID: 27515001.

Skjellegrind HK, Fayzullin A, Johnsen EO, Eide L, Langmoen IA, Moe MC, Vik-Mo EO. Short-Term Differentiation of Glioblastoma Stem Cells Induces Hypoxia Tolerance. Neurochem Res. 2016 Jul;41(7):1545-58. doi: 10.1007/s11064-016-1868-2. PubMed PMID: 26915110; PubMed Central PMCID: PMC4893075.

Kierulf-Vieira KS, Sandberg CJ, Grieg Z, Günther CC, Langmoen IA, Vik-Mo EO. Wnt inhibition is dysregulated in gliomas and its re-establishment inhibits proliferation and tumor sphere formation. Exp Cell Res. 2016 Jan 1;340(1):53-61. doi: 10.1016/j.yexcr.2015.12.010. PubMed PMID: 26712519.

Hytti M, Szabó D, Piippo N, Korhonen E, Honkakoski P, Kaarniranta K, Petrovski
G, Kauppinen A. Two dietary polyphenols, fisetin and luteolin, reduce
inflammation but augment DNA damage-induced toxicity in human RPE cells. J Nutr
Biochem. 2017 Jan 9;42:37-42. doi: 10.1016/j.jnutbio.2016.12.014. PubMed PMID: 28113103.

Nagymihály R, Veréb Z, Albert R, Sidney L, Dua H, Hopkinson A, Petrovski G.
Cultivation and characterisation of the surface markers and carbohydrate profile
of human corneal endothelial cells. Clin Exp Ophthalmol. 2016 Dec 29. doi:
10.1111/ceo.12903. PubMed PMID: 28032398.

Lumi X, Lužnik Z, Petrovski G, Petrovski BÉ, Hawlina M. Anatomical success
rate of pars plana vitrectomy for treatment of complex rhegmatogenous retinal
detachment. BMC Ophthalmol. 2016 Dec 9;16(1):216. PubMed PMID: 27938367; PubMed Central PMCID: PMC5148843.

Recek N, Andjelić S, Hojnik N, Filipič G, Lazović S, Vesel A, Primc G, Mozetič
M, Hawlina M, Petrovski G, Cvelbar U. Microplasma Induced Cell Morphological
Changes and Apoptosis of Ex Vivo Cultured Human Anterior Lens Epithelial Cells -
Relevance to Capsular Opacification. PLoS One. 2016 Nov 10;11(11):e0165883. doi:
10.1371/journal.pone.0165883. PubMed PMID: 27832099; PubMed Central PMCID:
PMC5104483.

Szatmári-Tóth M, Kristóf E, Veréb Z, Akhtar S, Facskó A, Fésüs L, Kauppinen A,
Kaarniranta K, Petrovski G. Clearance of autophagy-associated dying retinal
pigment epithelial cells - a possible source for inflammation in age-related
macular degeneration. Cell Death Dis. 2016 Sep 8;7(9):e2367. doi:
10.1038/cddis.2016.133. PubMed PMID: 27607582; PubMed Central PMCID: PMC5059849.

Gáspár R, Pipicz M, Hawchar F, Kovács D, Djirackor L, Görbe A, Varga ZV,
Kiricsi M, Petrovski G, Gácser A, Csonka C, Csont T. The cytoprotective effect of
biglycan core protein involves Toll-like receptor 4 signaling in cardiomyocytes.
J Mol Cell Cardiol. 2016 Oct;99:138-150. doi: 10.1016/j.yjmcc.2016.08.006. PubMed
PMID: 27515282.

Balogh E, Tóth A, Tolnai E, Bodó T, Bányai E, Szabó DJ, Petrovski G, Jeney V.
Osteogenic differentiation of human lens epithelial cells might contribute to
lens calcification. Biochim Biophys Acta. 2016 Sep;1862(9):1724-31. doi:
10.1016/j.bbadis.2016.06.012. PubMed PMID: 27318027.

Ivastinovic D, Schwab C, Mossböck G, Weger M, Pössl SL, Petrovski G, Wedrich
A, Velikay-Parel M. The configuration of the vitreomacular interface determines
the pattern of pseudophakic cystoid macular oedema. Acta Ophthalmol. 2016 May 26. doi: 10.1111/aos.13104. PubMed PMID: 27226394.

Veréb Z, Póliska S, Albert R, Olstad OK, Boratkó A, Csortos C, Moe MC, Facskó
A, Petrovski G. Role of Human Corneal Stroma-Derived Mesenchymal-Like Stem Cells in Corneal Immunity and Wound Healing. Sci Rep. 2016 May 19;6:26227. doi:
10.1038/srep26227. PubMed PMID: 27195722; PubMed Central PMCID: PMC4872602.

Koskela A, Reinisalo M, Petrovski G, Sinha D, Olmiere C, Karjalainen R,
Kaarniranta K. Nutraceutical with Resveratrol and Omega-3 Fatty Acids Induces
Autophagy in ARPE-19 Cells. Nutrients. 2016 May 11;8(5). pii: E284. doi:
10.3390/nu8050284. PubMed PMID: 27187449; PubMed Central PMCID: PMC4882697.

Eszes DJ, Szabó DJ, Russell G, Kirby P, Paulik E, Nagymajtényi L, Facskó A,
Moe MC, Petrovski BÉ. Diabetic Retinopathy Screening Using Telemedicine Tools:
Pilot Study in Hungary. J Diabetes Res. 2016;2016:4529824. doi:
10.1155/2016/4529824. PubMed PMID: 28078306; PubMed Central PMCID: PMC5204085.

Salvanos P, Moe MC, Utheim TP, Bragadóttir R, Kerty E. ULTRA-WIDE-FIELD FUNDUS IMAGING IN THE DIAGNOSIS AND FOLLOW-UP OF SUSAC SYNDROME. Retin Cases Brief Rep. 2016 Nov 8. PubMed PMID: 27828899.

Pathak M, Olstad OK, Drolsum L, Moe MC, Smorodinova N, Kalasova S, Jirsova K, Nicolaissen B, Noer A. The effect of culture medium and carrier on explant
culture of human limbal epithelium: A comparison of ultrastructure, keratin
profile and gene expression. Exp Eye Res. 2016 Dec;153:122-132. doi:
10.1016/j.exer.2016.09.012. PubMed PMID: 27702552.

Osnes-Ringen Ø, Berg KH, Moe MC, Zetterström C, Røger M, Nicolaissen B. Cell death pattern in lens epithelium of cataract patients. Acta Ophthalmol. 2016
Aug;94(5):514-20. doi: 10.1111/aos.13009. PubMed PMID: 27061232.

Skjellegrind HK, Fayzullin A, Johnsen EO, Eide L, Langmoen IA, Moe MC, Vik-Mo EO. Short-Term Differentiation of Glioblastoma Stem Cells Induces Hypoxia
Tolerance. Neurochem Res. 2016 Jul;41(7):1545-58. doi: 10.1007/s11064-016-1868-2. PubMed PMID: 26915110; PubMed Central PMCID: PMC4893075.

Holm KL, Indrevaer RL, Myklebust JH, Kolstad A, Moskaug JØ, Naderi EH, Blomhoff HK. Myeloid cell leukaemia 1 has a vital role in retinoic acid-mediated protection of Toll-like receptor 9-stimulated B cells from spontaneous and DNA damage-induced apoptosis. Immunology. 2016 Sep;149 (1):62-73.

Begic, Anadi; Isfoss, Björn L.; Lønnerød, Linn K.; Vigen, Alexander; Moskaug, Jan Ø. Survival and Inflammatory Response in Adipose-derived Mesenchymal Stem Cell-enriched Mouse Fat Grafts. Plastic and Reconstructive Surgery - Global Open . 4(12):e1110, December 2016.

Tekpli X, Urbanucci A, Hashim A, Vågbø CB, Lyle R, Kringen MK, Staff AC, Dybedal I, Mills IG, Klungland A, Staerk J. Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells. Epigenetics Chromatin. 2016 May 31;9:21.

Gamal W, Treskes P, Chesne CG, Samuel K, Sullivan GJ, Siller R, Srsen V, Underwood I, Smith S, Hayes PC, Plevris JN, Bagnaninchi PO and Nelson LJ. Low-dose acetaminophen disrupts cell-cell tight junctions in human hepatocytes and in vivo mouse liver. Scientific Reports. 2016:

Siller R, Naumovska E, Mathapati S, Lycke M and Sullivan GJ*. Development of a rapid screen for the endodermal differentiation potential of human pluripotent stem cell lines. Scientific Reports. 2016: DOI: 10.1038/srep37178. (*corresponding author).

Mathapati S, Siller R, Impellizzeri AR, Lycke M, Vegheim K, Almass R, Sullivan GJ*. Small molecule directed hepatocytes like cells differentiation of human pluripotent stem cells. Curr. Protoc. Stem Cell Biol. 2016: 38:1G.6.1-1G.6.18.doi: 10.1002/cpsc.13. (*corresponding author).

Xu M, Stattin E-L, Shaw G, Heinegård D, Sullivan G, Wilmut I, Colman A, Önnerfjord P, Khabut A, Aspberg A, Dockery P, Hardingham T, Murphy M, Barry F. Chondrocytes derived from mesenchymal stromal cells and induced pluripotent cells of patients with familial osteochondritis dissecans exhibit an ER stress response and defective matrix assembly. Stem Cells Transl. Med. 2016: 5:1171-1181.

Klungland A, Dahl JA, Greggains G, Fedorcsak P, Filipczyk A. Reversible RNA modifications in meiosis and pluripotency.Nat Methods. 2016 Dec 29;14(1):18-22. doi: 10.1038/nmeth.4111.

Feigelman J, Ganscha S, Hastreiter S, Schwarzfischer M, Filipczyk A, Schroeder T, Theis FJ, Marr C, Claassen M. Analysis of Cell Lineage Trees by Exact Bayesian Inference Identifies Negative Autoregulation of Nanog in Mouse Embryonic Stem Cells..Cell Syst. 2016 Nov 23;3(5):480-490.e13. doi: 10.1016/j.cels.2016.11.001.

Hoppe PS, Schwarzfischer M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Moritz N, Endele M, Filipczyk A, Gambardella A, Ahmed N, Etzrodt M, Coutu DL, Rieger MA, Marr C, Strasser MK, Schauberger B, Burtscher I, Ermakova O, Bürger A, Lickert H, Nerlov C, Theis FJ, Schroeder T. Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios. Nature. 2016 Jul 14;535(7611):299-302. doi: 10.1038/nature18320.

Hilsenbeck O, Schwarzfischer M, Skylaki S, Schauberger B, Hoppe PS, Loeffler D, Kokkaliaris KD, Hastreiter S, Skylaki E, Filipczyk A, Strasser M, Buggenthin F, Feigelman JS, Krumsiek J, van den Berg AJ, Endele M, Etzrodt M, Marr C, Theis FJ, Schroeder T. Software tools for single-cell tracking and quantification of cellular and molecular properties. Nat Biotechnol. 2016 Jul 12;34(7):703-6. doi: 10.1038/nbt.3626.

Hals IK, Ma Z, Singh R, Scholz H, Björklund A, Grill V. Culture at low glucose up-regulates mitochondrial function in pancreatic beta cells with accompanying effects on viability. Islets. 2016 Nov;8(6):165-176.

Halvorsen B, Santilli F*, Scholz H*, Saharoui A, Lattanzio, S, Formoso, G, Di Fulvio P, Kari Otterdal K, Gregersen I, Stavik B, Ueland T, Liani R, Davi G, Aukrust P. LIGHT/TNFSF14 is related to glycemic control in patients with type 2 diabetes mellitus and promotes endothelial cell inflammation and islet cell dysfunction in vitro. Diabetologia. 2016 Oct;59(10):2134-44. *co-Author

Kloster-Jensen K, Sahraoui A, Vethe NT, Bremer S, Korsgren O, Bergan S, Foss A, and Scholz H. Treatment with tacrolimus and sirolimus reveals no additional adverse effects on human islets in vitro compared to each drug alone but are reduced by adding glucocorticoids. J Diabetes Res. 2016;2016:4196460.

 

2015

Joel M, Mughal AA, Grieg Z, Murrell W, Palmero S, Mikkelsen B, Fjerdingstad HB, Sandberg CJ, Behnan J, Glover JC, Langmoen IA, Stangeland B. Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo. Mol Cancer. 2015 Jun 17;14:121. doi: 10.1186/s12943-015-0398-x.

Kasumacic N, Lambert FM, Coulon P, Bras H, Vinay L, Perreault MC, Glover JC. Segmental organization of vestibulospinal inputs to spinal interneurons mediating crossed activation of thoracolumbar motoneurons in the neonatal mouse. J Neurosci. 2015 May 27;35(21):8158-69. doi: 10.1523/JNEUROSCI.5188-14.2015.       

 Blacklaws J, Deska-Gauthier D, Jones CT, Petracca YL, Liu M, Zhang H, Fawcett JP, Glover JC, Lanuza GM, Zhang Y. Sim1 is required for the migration and axonal projections of V3 interneurons in the developing mouse spinal cord. Dev Neurobiol. 2015 Sep;75(9):1003-17. doi: 10.1002/dneu.22266. Epub 2015 Feb 18.

Rønningen T, Shah A, Oldenburg A, Vekterud K, Delbarre E, Moskaug JØ, Collas P. Pre-patterning of differentiation-driven nuclear lamin A/C-associated chromatin domains by GlcNAcylated histone H2B. Genome Res. 2015 Sep 10. pii: gr.193748.115. [Epub ahead of print]

Taghdouini AE, Sørensen AL, Reiner AH, Coll M, Verhulst S, Mannaerts I, Øie CI, Smedsrød B, Najimi M, Sokal E, Luttun A, Sancho-Bru P, Collas P, van Grunsven LA. Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells. Oncotarget. 2015 Aug 31. [Epub ahead of print]

Udugama M, Chang FT, Chan FL, Tang MC, Pickett HA, McGhie JD, Mayne L, Collas P, Mann JR, Wong LH. Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres. Nucleic Acids Res. 2015 Aug 24. pii: gkv847. [Epub ahead of print]

Paulsen J, Gramstad O, Collas P. Manifold Based Optimization for Single-Cell 3D Genome Reconstruction. PLoS Comput Biol. 2015 Aug 11;11(8):e1004396. doi: 10.1371/journal.pcbi.1004396. eCollection 2015 Aug.

Lund EG, Collas P, Delbarre E. Transcription outcome of promoters enriched in histone variant H3.3 defined by positioning of H3.3 and local chromatin marks. Biochem Biophys Res Commun. 2015 May 1;460(2):348-53. doi: 10.1016/j.bbrc.2015.03.037. Epub 2015 Mar 14.

Chang FT, Chan FL, R McGhie JD, Udugama M, Mayne L, Collas P, Mann JR, Wong LH. CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells. Nucleic Acids Res. 2015 Mar 11;43(5):2603-14. doi: 10.1093/nar/gkv104. Epub 2015 Feb 17.

Lund EG, Duband-Goulet I, Oldenburg A, Buendia B, Collas P. Distinct features of lamin A-interacting chromatin domains mapped by ChIP-sequencing from sonicated or micrococcal nuclease-digested chromatin. Nucleus. 2015;6(1):30-9. doi: 10.4161/19491034.2014.990855.

Pullisaar H, Verket A, Szoke K, Tiainen H, Haugen HJ, Brinchmann JE, Reseland JE, Østrup E. Alginate hydrogel enriched with enamel matrix derivative to target osteogenic cell differentiation in TiO2 scaffolds. J Tissue Eng. 2015 Mar 12;6:2041731415575870. doi: 10.1177/2041731415575870. eCollection 2015.

Hart ML, Izeta A, Herrera-Imbroda B, Amend B, Brinchmann JE. Cell Therapy for Stress Urinary Incontinence. Tissue Eng Part B Rev. 2015 Aug;21(4):365-76. doi: 10.1089/ten.TEB.2014.0627. Epub 2015 Apr 22. 

Stangeland B, Mughal AA, Grieg Z, Sandberg CJ, Joel M, Nygård S, Meling T, Murrell W, Vik Mo EO, Langmoen IA. Combined expressional analysis, bioinformatics and targeted proteomics identify new potential therapeutic targets in glioblastoma stem cells. Oncotarget. 2015 Jul 20. [Epub ahead of print] 

Mughal AA, Grieg Z, Skjellegrind H, Fayzullin A, Lamkhannat M, Joel M, Ahmed MS, Murrell W, Vik-Mo EO, Langmoen IA, Stangeland B. Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells. Mol Cancer. 2015 Aug 21;14(1):160. doi: 10.1186/s12943-015-0432-z. 

Halvorsen CM, Rønning P, Hald J, Johannesen TB, Kolstad F, Langmoen IA, Lied B, Skaar Holme S, Helseth E. The Long-term Outcome After Resection of Intraspinal Nerve Sheath Tumors: Report of 131 Consecutive Cases. Neurosurgery. 2015 Jul 4. [Epub ahead of print]

Rustad EH, Dai HY, Hov H, Coward E, Beisvag V, Myklebost O, Hovig E, Nakken S, Vodák D, Meza-Zepeda LA, Sandvik AK, Wader KF, Misund K, Sundan A, Aarset H, Waage A. BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis. Blood Cancer J. 2015 Mar 20;5:e299. doi: 10.1038/bcj.2015.24. 

Serguienko A, Grad I, Wennerstrøm AB, Meza-Zepeda LA, Thiede B, Stratford EW, Myklebost O, Munthe E. Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA. Oncotarget. 2015 Feb 10;6(4):2451-65. 

Naderi EH, Skah S, Ugland H, Myklebost O, Sandnes DL, Torgersen ML, Josefsen D, Ruud E, Naderi S, Blomhoff HK. Bone marrow stroma-derived PGE2 protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death. Mol Cancer. 2015 Jan 27;14:14. doi: 10.1186/s12943-014-0278-9. 

Roald AB, Aass HC, Moe MC. Recovery of plasma vascular endothelial growth factor concentrations during aflibercept loading phase and after the transition to bimonthly treatment for neovascular age-related macular degeneration. Br J Ophthalmol. 2015 May 12. pii: bjophthalmol-2015-306781. doi: 10.1136/bjophthalmol-2015-306781. [Epub ahead of print] 

Salvanos P, Utheim TP, Moe MC, Eide N, Bragadόttir R. Autofluorescence imaging in the differential diagnosis of optic disc melanocytoma. Acta Ophthalmol. 2015 Aug;93(5):476-80. doi: 10.1111/aos.12725. Epub 2015 Apr 28. 

Lumi X, Hawlina M, Glavač D, Facskó A, Moe MC, Kaarniranta K, Petrovski G. Ageing of the vitreous: From acute onset floaters and flashes to retinal detachment. Ageing Res Rev. 2015 May;21:71-7. doi: 10.1016/j.arr.2015.03.006. Epub 2015 Apr 2. Review. 

Jørstad ØK, Faber RT, Moe MC. Initial improvements when converting eyes with treatment-resistant exudative AMD to aflibercept are substantially diminished after increasing treatment intervals from 4 to 8 weeks. Acta Ophthalmol. 2015 Feb 23. doi: 10.1111/aos.12681. [Epub ahead of print] No abstract available.  

Indrevær RL, Moskaug JØ, Paur I, Bøhn SK, Jørgensen SF, Blomhoff R, Aukrust P, Fevang B, Blomhoff HK. IRF4 Is a Critical Gene in Retinoic Acid-Mediated Plasma Cell Formation and Is Deregulated in Common Variable Immunodeficiency-Derived B Cells. J Immunol. 2015 Sep 15;195(6):2601-11. doi: 10.4049/jimmunol.1500250. Epub 2015 Aug 14. 

Eriksen AB, Torgersen ML, Holm KL, Abrahamsen G, Spurkland A, Moskaug JØ, Simonsen A, Blomhoff HK. Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy. Autophagy. 2015;11(3):460-71. doi: 10.1080/15548627.2015.1009797. 

Ougland R, Rognes T, Klungland A, Larsen E. Non-homologous functions of the AlkB homologs. J Mol Cell Biol. 2015 May 23. pii: mjv029. [Epub ahead of print] Review. 

Chymkowitch P, Nguéa AP, Aanes H, Koehler CJ, Thiede B, Lorenz S, Meza-Zepeda LA, Klungland A, Enserink JM. Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes. Genome Res. 2015 Jun;25(6):897-906. doi: 10.1101/gr.185793.114. Epub 2015 Mar 23. 

Seeberg TM, Austad HO, Clausen I, Cederkvist H, Bjørås M, Johansen RF. An in vitro Study of Protein Adsorption to Biocompatible Coatings. Stud Health Technol Inform. 2015;211:166-71. 

Dalhus B, Alseth I, Bjørås M. Structural basis for incision at deaminated adenines in DNA and RNA by endonuclease V. Prog Biophys Mol Biol. 2015 Mar;117(2-3):134-42. doi: 10.1016/j.pbiomolbio.2015.03.005. Epub 2015 Mar 28. Review. 

Bliksøen M, Baysa A, Eide L, Bjørås M, Suganthan R, Vaage J, Stensløkken KO, Valen G. Mitochondrial DNA damage and repair during ischemia-reperfusion injury of the heart. J Mol Cell Cardiol. 2015 Jan;78:9-22. doi: 10.1016/j.yjmcc.2014.11.010. Epub 2014 Nov 18. 

Almåsbak H, Walseng E, Kristian A, Myhre MR, Suso EM, Munthe LA, Andersen JT, Wang MY, Kvalheim G, Gaudernack G, Kyte JA. Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model. Gene Ther. 2015 May;22(5):391-403. doi: 10.1038/gt.2015.4. Epub 2015 Feb 5. 

Eide N, Faye RS, Høifødt HK, Sandstad B, Qvale G, Faber R, Jebsen P, Kvalheim G, Fodstad Ø. Immunomagnetic detection of micrometastatic cells in bone marrow of uveal melanoma patients: a paradox. Acta Ophthalmol. 2015 Feb;93(1):59-66. doi: 10.1111/aos.12462.

 

2014

Sivertsen MS, Glover JC, Perreault MC (2014)
Organization of pontine reticulospinal inputs to motoneurons controlling axial and limb muscles in the neonatal mouse.
J Neurophysiol. 2014 Jun 18. pii: jn.00820.2013. [Epub ahead of print]

Straka H, Fritzsch B, Glover JC. (2014)
Connecting ears to eye muscles: evolution of a 'simple' reflex arc.
Brain Behav Evol. 2014;83(2):162-75.

Bjørnstad S, Paulsen RE, Erichsen A, Glover JC, Roald B. (2014)
Type I and II pneumocyte differentiation in the developing fetal chicken lung: conservation of pivotal proteins from birds to human in the struggle for life at birth.
Neonatology. 2014;105(2):112-20.

Glover JC (2014) 
Conjugate dextran amines as intracellular tracers for visualizing and manipulating neurons. (2014) In: Dextran: Chemical Structure, Applications and Potential Side Effects. Recent Trends in Biotechnology.
Ed: Garrett P. Figgs. Nova Publishers, ISBN: 978-1-62948-960-5.

Østrup O, Reiner AH, Aleström P, Collas P. (2014)
The specific alteration of histone methylation profiles by DZNep during early zebrafish development.
Biochim Biophys Acta. 2014 Sep 28;1839(11):1307-1315. doi: 10.1016/j.bbagrm.2014.09.013. [Epub ahead of print]

Reppe S, Noer A, Grimholt RM, Halldórsson BV, Medina-Gomez C, Gautvik VT, Olstad OK, Berg JP, Datta H, Estrada K, Hofman A, Uitterlinden AG, Rivadeneira F, Lyle R, Collas P, Gautvik KM. (2014)
Methylation of bone SOST, its mRNA, and serum sclerostin levels correlate strongly with fracture risk in postmenopausal women.
J Bone Miner Res. 2014 Aug 22. doi: 10.1002/jbmr.2342. [Epub ahead of print]

Ivanauskiene K, Delbarre E, McGhie JD, Küntziger T, Wong LH, Collas P. (2014)
The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity. 
Genome Res. 2014 Jul 21. pii: gr.173831.114. [Epub ahead of print]

Carrière A, Jeanson Y, Berger-Müller S, André M, Chenouard V, Arnaud E, Barreau C, Walther R, Galinier A, Wdziekonski B, Villageois P, Louche K, Collas P, Moro C, Dani C, Villarroya F, Casteilla L. (2014)
Browning of White Adipose Cells by Intermediate Metabolites:An Adaptive Mechanism to Alleviate Redox Pressure.
Diabetes. 2014 May 1. [Epub ahead of print]

Lund E, Oldenburg AR, Collas P. (2014)
Enriched domain detector: a program for detection of wide genomic enrichment domains robust against local variations.
Nucleic Acids Res. 2014;42(11):e92. doi: 10.1093/nar/gku324. Epub 2014 Apr 29.

Aanes H, Winata C, Moen LF, Østrup O, Mathavan S, Collas P, Rognes T, Aleström P. (2014)
Normalization of RNA-sequencing data from samples with varying mRNA levels.
PLoS One. 2014 Feb 25;9(2):e89158. doi: 10.1371/journal.pone.0089158. eCollection 2014.

Aanes H, Collas P, Aleström P. (2014)
Transcriptome dynamics and diversity in the early zebrafish embryo.
Brief Funct Genomics. 2014 Mar;13(2):95-105. doi: 10.1093/bfgp/elt049. Epub 2013 Dec 12.

Collas P, Lund EG, Oldenburg AR. (2014)
Closing the (nuclear) envelope on the genome: how nuclear lamins interact with promoters and modulate gene expression.
Bioessays. 2014 Jan;36(1):75-83. doi: 10.1002/bies.201300138. Epub 2013 Nov 24.

Shah, A., Oldenburg, A.R., Collas, P. (2014)
A hyper-dynamic nature of bivalent promoter states underlies coordinated developmental gene expression modules. BMC Genomics 15, 1186.

Vadrot N, Duband-Goulet I, Cabet E, Attanda W, Barateau A, Vicart P, Gerbal F, Briand N, Vigouroux C, Oldenburg AR, Lund EG, Collas P, Buendia B. (2014)
The p.R482W substitution in A-type lamins deregulates SREBP1 activity in Dunnigan-type familial partial lipodystrophy. Hum. Mol. Genet. PMID: 25524705.

Jakobsen RB, Østrup E, Zhang X, Mikkelsen TS, Brinchmann JE. (2014)
Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling
PLoS One. 2014 May 9;9(5):e96615. doi: 10.1371/journal.pone.0096615. eCollection 2014. PMID: 24816923 [PubMed - in process]

Pullisaar H, Reseland JE, Haugen HJ, Brinchmann JE, Østrup E. (2014)
Simvastatin coating of TiO₂ scaffold induces osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells.
Biochem Biophys Res Commun. 2014 Apr 25;447(1):139-44. doi: 10.1016/j.bbrc.2014.03.133. Epub 2014 Apr 2.

Olderøy MØ, Lilledahl MB, Beckwith MS, Melvik JE, Reinholt F, Sikorski P, Brinchmann JE. (2014)
Biochemical and structural characterization of neocartilage formed by mesenchymal stem cells in alginate hydrogels.
PLoS One. 2014 Mar 13;9(3):e91662. doi: 10.1371/journal.pone.0091662. eCollection 2014.

Herlofsen SR, Høiby T, Cacchiarelli D, Zhang X, Mikkelsen TS, Brinchmann JE. (2014)
Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells.
Stem Cells. 2014 Jun;32(6):1629-35. doi: 10.1002/stem.1642.

Karlsen TA, Jakobsen RB, Mikkelsen TS, Brinchmann JE. (2014)
microRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN.
Stem Cells Dev. 2014 Feb 1;23(3):290-304. doi: 10.1089/scd.2013.0209. Epub 2013 Nov 7

Behnan J, Isakson P, Joel M, Cilio C, Langmoen IA, Vik-Mo EO, Badn W. (2014)
Recruited brain tumor-derived mesenchymal stem cells contribute to brain tumor progression.
Stem Cells. 2014 May;32(5):1110-23. doi: 10.1002/stem.1614.

Sandberg CJ, Vik-Mo EO, Behnan J, Helseth E, Langmoen IA. (2014)
Transcriptional profiling of adult neural stem-like cells from the human brain.
PLoS One. 2014 Dec 16;9(12):e114739.

Berg-Johnsen J, Helseth E, Langmoen IA. (2014)
Cerebral revascularization for skull base tumors.
World Neurosurg. 2014 Nov;82(5):575-6.

Garsed DW, Marshall OJ, Corbin VD, Hsu A, Di Stefano L, Schröder J, Li J, Feng ZP, Kim BW, Kowarsky M, Lansdell B, Brookwell R, Myklebost O, Meza-Zepeda L, Holloway AJ, Pedeutour F, Choo KH, Damore MA, Deans AJ, Papenfuss AT, Thomas DM. (2014) The architecture and evolution of cancer neochromosomes.
Cancer Cell. 2014 Nov 10;26(5):653-67

Wennerström AB, Lothe IM, Sandhu V, Kure EH, Myklebost O, Munthe E. (2014)
Generation and characterisation of novel pancreatic adenocarcinoma xenograft models and corresponding primary cell lines.
PLoS One. 2014 Aug 22;9(8):e103873. doi: 10.1371/journal.pone.0103873. eCollection 2014.

Chilamakuri CS, Lorenz S, Madoui MA, Vodák D, Sun J, Hovig E, Myklebost O, Meza-Zepeda LA.(2014)
Performance comparison of four exome capture systems for deep sequencing.
BMC Genomics. 2014 Jun 9;15:449. doi: 10.1186/1471-2164-15-449.

Håkelien AM, Bryne JC, Harstad KG, Lorenz S, Paulsen J, Sun J, Mikkelsen TS, Myklebost O, Meza-Zepeda LA. (2014)
The regulatory landscape of osteogenic differentiation.
Stem Cells. 2014 Oct;32(10):2780-93. doi: 10.1002/stem.1759.

Barøy T, Kresse SH, Skårn M, Stabell M, Castro R, Lauvrak S, Llombart-Bosch A, Myklebost O, Meza-Zepeda LA. (2014)
Reexpression of LSAMP inhibits tumor growth in a preclinical osteosarcoma model.
Mol Cancer. 2014 Apr 28;13:93. doi: 10.1186/1476-4598-13-93.

Skårn M, Noordhuis P, Wang MY, Veuger M, Kresse SH, Egeland EV, Micci F, Namløs HM, Håkelien AM, Olafsrud SM, Lorenz S, Haraldsen G, Kvalheim G, Meza-Zepeda LA, Myklebost O. (2014)
Generation and characterization of an immortalized human mesenchymal stromal cell line.
Stem Cells Dev. 2014 Oct 1;23(19):2377-89. doi: 10.1089/scd.2013.0599. Epub 2014 Jun 30.

Stratford EW, Daffinrud J, Munthe E, Castro R, Waaler J, Krauss S, Myklebost O. (2014)
The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines.
Cancer Med. 2014 Feb;3(1):36-46. doi: 10.1002/cam4.170. Epub 2013 Dec 17.

Petrovski G, Pasztor K, Orosz L, Albert R, Mencel E, Moe MC, Kaarniranta K, Facsko A, Megyeri K. (2014)
Herpes simplex virus types 1 and 2 modulate autophagy in SIRC corneal cells.
J Biosci. 2014 Sep;39(4):683-92.

Andjelić S, Lumi X, Yan X, Graw J, Moe MC, Facskó A, Hawlina M, Petrovski G. (2014)
Characterization of ex vivo cultured neuronal- and glial- like cells from human idiopathic epiretinal membranes.
BMC Ophthalmol. 2014 Dec 23;14:165.

Preda MB, Rønningen T, Burlacu A, Simionescu M, Moskaug JØ, Valen G. (2014)
Remote transplantation of mesenchymal stem cells protects the heart against ischemia-reperfusion injury.
Stem Cells. 2014 Aug;32(8):2123-34. doi: 10.1002/stem.1687.

Robertson AB, Robertson J, Fusser M, Klungland A. (2014)
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination.
Nucleic Acids Res. 2014 Dec 1;42(21):13280-93

Dahl JA, Klungland A. (2014)
Micro Chromatin Immunoprecipitation (μChIP) from Early Mammalian Embryos.
Methods Mol Biol. 2015;1222:227-45. doi: 10.1007/978-1-4939-1594-1_17.

Nilsen A, Fusser M, Greggains G, Fedorcsak P, Klungland A. (2014)
ALKBH4 depletion in mice leads to spermatogenic defects.
PLoS One. 2014 Aug 25;9(8):e105113. doi: 10.1371/journal.pone.0105113. eCollection 2014.

Klungland A, Dahl JA. (2014)
Dynamic RNA modifications in disease.
Curr Opin Genet Dev. 2014 Jul 5;26C:47-52. doi: 10.1016/j.gde.2014.05.006. [Epub ahead of print] Review.

Robertson AB, Dahl JA, Klungland A. (2014)
DNA metabolism: bases of DNA repair and regulation.
Nat Chem Biol. 2014 Jul;10(7):487-8. doi: 10.1038/nchembio.1553.

Zdżalik D, Vågbø CB, Kirpekar F, Davydova E, Puścian A, Maciejewska AM, Krokan HE, Klungland A, Tudek B, van den Born E, Falnes PØ. (2014)
Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities.
PLoS One. 2014 Jun 10;9(6):e98729. doi: 10.1371/journal.pone.0098729. eCollection 2014

Yang M, Luna L, Sørbø JG, Alseth I, Johansen RF, Backe PH, Danbolt NC, Eide L, Bjørås M. (2014)
Human OXR1 maintains mitochondrial DNA integrity and counteracts hydrogen peroxide-induced oxidative stress by regulating antioxidant pathways involving p21.
Free Radic Biol Med. 2014 Sep 16;77C:41-48. doi: 10.1016/j.freeradbiomed.2014.09.003. [Epub ahead of print]

Alseth I, Dalhus B, Bjørås M. (2014)
Inosine in DNA and RNA.
Curr Opin Genet Dev. 2014 Aug 28;26C:116-123. doi: 10.1016/j.gde.2014.07.008. [Epub ahead of print] Review.

Stray-Pedersen A, Backe PH, Sorte HS, Mørkrid L, Chokshi NY, Erichsen HC, Gambin T, Elgstøen KB, Bjørås M, Wlodarski MW, Krüger M, Jhangiani SN, Muzny DM, Patel A, Raymond KM, Sasa GS, Krance RA, Martinez CA, Abraham SM, Speckmann C, Ehl S, Hall P, Forbes LR, Merckoll E, Westvik J, Nishimura G, Rustad CF, Abrahamsen TG, Rønnestad A, Osnes LT, Egeland T, Rødningen OK, Beck CR; Baylor-Johns Hopkins Center for Mendelian Genomics, Boerwinkle EA, Gibbs RA, Lupski JR, Orange JS, Lausch E, Hanson IC. (2014)
PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia.
Am J Hum Genet. 2014 Jul 3;95(1):96-107. doi: 10.1016/j.ajhg.2014.05.007. Epub 2014 Jun 12.

Strand JM, Skinnes R, Scheffler K, Rootvelt T, Woldseth B, Bjørås M, Eide L. (2014)
Genome instability in Maple Syrup Urine Disease correlates with impaired mitochondrial biogenesis.
Metabolism. 2014 Aug;63(8):1063-70. doi: 10.1016/j.metabol.2014.05.003. Epub 2014 May 9.

Wang W, Scheffler K, Esbensen Y, Strand JM, Stewart JB, Bjørås M, Eide L. (2014)
Addressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age.
PLoS One. 2014 May 12;9(5):e96940. doi: 10.1371/journal.pone.0096940. eCollection 2014.

Sand KM, Dalhus B, Christianson GJ, Bern M, Foss S, Cameron J, Sleep D, Bjørås M, Roopenian DC, Sandlie I, Andersen JT. (2014)
Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies.
J Biol Chem. 2014 Jun 13;289(24):17228-39. doi: 10.1074/jbc.M113.522565. Epub 2014 Apr 24.

Strand JM, Scheffler K, Bjørås M, Eide L. (2014)
The distribution of DNA damage is defined by region-specific susceptibility to DNA damage formation rather than repair differences.
DNA Repair (Amst). 2014 Jun;18:44-51. doi: 10.1016/j.dnarep.2014.03.003. Epub 2014 Mar 27.

Andersen JT, Dalhus B, Viuff D, Ravn BT, Gunnarsen KS, Plumridge A, Bunting K, Antunes F, Williamson R, Athwal S, Allan E, Evans L, Bjørås M, Kjærulff S, Sleep D, Sandlie I, Cameron J. (2014)
Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding.
J Biol Chem. 2014 May 9;289(19):13492-502. doi: 10.1074/jbc.M114.549832. Epub 2014 Mar 20.

Aamann MD, Hvitby C, Popuri V, Muftuoglu M, Lemminger L, Skeby CK, Keijzers G, Ahn B, Bjørås M, Bohr VA, Stevnsner T. (2014)
Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity.
Mech Ageing Dev. 2014 Jan;135:1-14. doi: 10.1016/j.mad.2013.12.008. Epub 2014 Jan 7.

Kolstad A, Kumari S, Walczak M, Madsbu U, Hagtvedt T, Bogsrud TV, Kvalheim G, Holte H, Aurlien E, Delabie J, Tierens A, Olweus J. (2014)
Sequential intranodal immunotherapy induces anti-tumor immunity and correlated regression of disseminated follicular lymphoma.
Blood. 2014 Oct 7. pii: blood-2014-07-592162. [Epub ahead of print]

Subklewe M, Geiger C, Lichtenegger FS, Javorovic M, Kvalheim G, Schendel DJ, Bigalke I. (2014)
New generation dendritic cell vaccine for immunotherapy of acute myeloid leukemia.
Cancer Immunol Immunother. 2014 Oct;63(10):1093-103. doi: 10.1007/s00262-014-1600-5. Epub 2014 Sep 4.

Husøy MA, Brinch L, Tjønnfjord GE, Gedde-Dahl D Y T, Heldal D, Holme PA, Dybedal I, Kolstad A, Akkök CA, Rollag H, Gaustad P, Bergan S, Egeland T, Josefsen D, Kvalheim G, Fløisand Y. (2014)
[Allogeneic stem-cell transplantation in adults 1985 - 2012: Results and development].
Tidsskr Nor Laegeforen. 2014 Sep 2;134(16):1569-75. doi: 10.4045/tidsskr.13.1415. eCollection 2014 Sep. Norwegian.

Skårn M, Noordhuis P, Wang MY, Veuger M, Kresse SH, Egeland EV, Micci F, Namløs HM, Håkelien AM, Olafsrud SM, Lorenz S, Haraldsen G, Kvalheim G, Meza-Zepeda LA, Myklebost O. (2014)
Generation and characterization of an immortalized human mesenchymal stromal cell line.
Stem Cells Dev. 2014 Oct 1;23(19):2377-89. doi: 10.1089/scd.2013.0599. Epub 2014 Jun 30.

Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead AJ, Stenson L, Giustacchini A, Duarte S, Giannoulatou E, Taylor S, Karimi M, Scharenberg C, Mortera-Blanco T, Macaulay IC, Clark SA, Dybedal I, Josefsen D, Fenaux P, Hokland P, Holm MS, Cazzola M, Malcovati L, Tauro S, Bowen D, Boultwood J, Pellagatti A, Pimanda JE, Unnikrishnan A, Vyas P, Göhring G, Schlegelberger B, Tobiasson M, Kvalheim G, Constantinescu SN, Nerlov C, Nilsson L, Campbell PJ, Sandberg R, Papaemmanuil E, Hellström-Lindberg E, Linnarsson S, Jacobsen SE. (2014)
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.
Cancer Cell. 2014 Jun 16;25(6):794-808. doi: 10.1016/j.ccr.2014.03.036. Epub 2014 May 15. Erratum in: Cancer Cell. 2014 Jun 16;25(6):861.

 

2013

Skårn M, Barøy T, Stratford EW, Myklebost O. (2013) 
Epigenetic Regulation and Functional Characterization of MicroRNA-142 in Mesenchymal Cells. 
PLoS One. 2013 Nov 13;8(11):e79231. 

Karlsen TA, Jakobsen RB, Mikkelsen TS, Brinchmann JE.
microRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN.
Stem Cells Dev. 2013 Nov 7. [Epub ahead of print] 

Dajani R, Koo SE, Sullivan GJ, Park IH (2013) 
Investigation of Rett syndrome using pluripotent stem cells. 
J Cell Biochem. 2013 Nov;114(11):2446-53. 

Smeland KB, Kiserud CE, Lauritzsen GF, Fosså A, Hammerstrøm J, Jetne V, Kolstad A, Kvalheim G, Loge JH, Løkeland T, Tangen JM, Holte H, Kvaløy S (2013)
High-dose therapy with autologous stem cell support for lymphoma - from experimental to standard treatment.
Tidsskr Nor Laegeforen. 2013 Sep 3;133(16):1735-1739. 

Vik-Mo EO, Nyakas M, Mikkelsen BV, Moe MC, Due-Tønnesen P, Suso EM, Sæbøe-Larssen S, Sandberg C, Brinchmann JE, Helseth E, Rasmussen AM, Lote K, Aamdal S, Gaudernack G, Kvalheim G, Langmoen IA (2013) Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma. 
Cancer Immunol Immunother. 2013 Sep;62(9):1499-509. Epub 2013 Jul 2. 

Boulland JL, Lambert FM, Züchner M, Ström S, Glover JC (2013)
A neonatal mouse spinal cord injury model for assessing post-injury adaptive plasticity and human stem cell integration. 
PLoS One. 2013 Aug 19;8(8):e71701. 

Sandberg CJ, Altschuler G, Jeong J, Strømme KK, Stangeland B, Murrell W, Grasmo-Wendler UH, Myklebost O, Helseth E, Vik-Mo EO, Hide W, Langmoen IA (2013)
Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt- signaling and a fingerprint associated with clinical outcome. 
Exp Cell Res. 2013 Aug 15;319(14):2230-43. Epub 2013 Jun 18. 

Wang P, Suo Z, Wang M, Høifødt HK, Fodstad O, Gaudernack G, Kvalheim G (2013) 
In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines. 
Exp Hematol Oncol. 2013 Jun 6;2(1):16. 

Hemmingsen M, Vedel S, Skafte-Pedersen P, Sabourin D, Collas P, Bruus H, Dufva M (2013) 
The Role of Paracrine and Autocrine Signaling in the Early Phase of Adipogenic Differentiation of Adipose-derived Stem Cells. 
PLoS One. 2013 May 28;8(5):e63638. 

Kaur K, Mirlashari MR, Kvalheim G, Kjeldsen-Kragh J (2013) 
3',4'-Dimethoxyflavone and valproic acid promotes the proliferation of human hematopoietic stem cells. 
Stem Cell Res Ther. 2013 May 24;4(3):60. 

Kuijjer ML, Peterse EF, van den Akker BE, Briaire-de Bruijn IH, Serra M, Meza-Zepeda LA, Myklebost O, Hassan AB, Hogendoorn PC, Cleton-Jansen AM (2013) 
IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma. BMC Cancer. 
2013 May 20;13:245. 

Aanes H, Ostrup O, Andersen IS, Moen LF, Mathavan S, Collas P, Alestrom P (2013) 
Differential transcript isoform usage pre- and post-zygotic genome activation in zebrafish. 
BMC Genomics. 2013 May 15;14(1):331. 

Li MM, Nilsen A, Shi Y, Fusser M, Ding YH, Fu Y, Liu B, Niu Y, Wu YS, Huang CM, Olofsson M, Jin KX, Lv Y, Xu XZ, He C, Dong MQ, Rendtlew Danielsen JM, Klungland A, Yang YG (2013) 
ALKBH4-dependent demethylation of actin regulates actomyosin dynamics. 
Nat Commun. 2013;4:1832. 

Fernandes AM, Herlofsen SR, Karlsen TA, Küchler AM, Fløisand Y, Brinchmann JE (2013) 
Similar properties of chondrocytes from osteoarthritis joints and mesenchymal stem cells from healthy donors for tissue engineering of articular cartilage. 
PLoS One. 2013 May 9;8(5):e62994. 

Stratford EW, Bostad M, Castro R, Skarpen E, Berg K, Høgset A, Myklebost O, Selbo PK (2013) Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity. 
Biochim Biophys Acta. 2013 Aug;1830(8):4235-43. doi: 10.1016/j.bbagen.2013.04.033. Epub 2013 May 2. 

Østrup O, Olbricht G, Østrup E, Hyttel P, Collas P, Cabot R (2013) 
RNA profiles of porcine embryos during genome activation reveal complex metabolic switch sensitive to in vitro conditions. 
PLoS One. 2013 Apr 29;8(4):e61547. doi: 10.1371/journal.pone.0061547. Print 2013. 

Liu Y, Wu X, Li X, Kvalheim G, Axcrona U, Axcrona K, Suo Z (2013) 
Blocking mtDNA Replication Upregulates the Expression of Stemness-related Genes in Prostate Cancer Cell Lines. 
Ultrastruct Pathol. 2013 May 1. 

Furu K, Klungland A (2013) 
Tzfp represses the androgen receptor in mouse testis. 
PLoS One. 2013 Apr 25;8(4):e62314. doi: 10.1371/journal.pone.0062314. Print 2013. 

Backe PH, Simm R, Laerdahl JK, Dalhus B, Fagerlund A, Okstad OA, Rognes T, Alseth I, Kolstø AB, Bjørås M (2013) 
A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures. 
J Struct Biol. 2013 Apr 25. doi:pii: S1047-8477(13)00107-X. 10.1016/j.jsb.2013.04.007. 

Sioud M, Sæbøe-Larssen S, Hetland TE, Kærn J, Mobergslien A, Kvalheim G (2013) 
Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients. Int J Oncol. 2013 Jul;43(1):280-8. doi: 10.3892/ijo.2013.1922. Epub 2013 Apr 25. 

Zheng G, Dahl JA, Niu Y, Fu Y, Klungland A, Yang YG, He C (2013) 
Sprouts of RNA epigenetics: The discovery of mammalian RNA demethylases. 
RNA Biol. 2013 Apr 17;10(6). 

Andersen IS, Lindeman LC, Reiner AH, Østrup O, Aanes H, Aleström P, Collas P (2013) 
Epigenetic marking of the zebrafish developmental program. 
Curr Top Dev Biol. 2013;104:85-112. doi: 10.1016/B978-0-12-416027-9.00003-6. 

Solberg A, Robertson AB, Aronsen JM, Rognmo O, Sjaastad I, Wisløff U, Klungland A (2013) 
Deletion of mouse Alkbh7 leads to obesity. 
J Mol Cell Biol. 2013 Jun;5(3):194-203. doi: 10.1093/jmcb/mjt012. Epub 2013 Apr 8. 

Karlsen TA, Brinchmann JE (2013) 
Liposome Delivery of MicroRNA-145 to Mesenchymal Stem Cells Leads to Immunological Off-target Effects Mediated by RIG-I. Mol Ther. 2013 Jun;21(6):1169-81. doi: 10.1038/mt.2013.55. Epub 2013 Apr 9. 

Bianchini L, Birtwisle L, Saâda E, Bazin A, Long E, Roussel JF, Michiels JF, Forest F, Dani C, Myklebost O, Birtwisle-Peyrottes I, Pedeutour F (2013) 
Identification of PPAP2B as a novel recurrent translocation partner gene of HMGA2 in lipomas.Genes Chromosomes Cancer. 2013 Jun;52(6):580-90. doi: 10.1002/gcc.22055. Epub 2013 Mar 18. 

Wang P, Gao Q, Suo Z, Munthe E, Solberg S, Ma L, Wang M, Westerdaal NA, Kvalheim G, Gaudernack G (2013) 
Identification and characterization of cells with cancer stem cell properties in human primary lung cancer cell lines. PLoS One. 2013;8(3):e57020. doi: 10.1371/journal.pone.0057020. Epub 2013 Mar 4. 

Siller R, Greenhough S, Park IH, Sullivan GJ (2013) 
Modelling human disease with pluripotent stem cells. 
Curr Gene Ther. 2013 Apr;13(2):99-110. 

Herlofsen SR, Bryne JC, Høiby T, Wang L, Issner R, Zhang X, Coyne MJ, Boyle P, Gu H, Meza-Zepeda LA, Collas P, Mikkelsen TS, Brinchmann JE (2013) 
Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells. BMC Genomics. 2013 Feb 15;14:105. doi: 10.1186/1471-2164-14-105. 

Weel-Sneve R, Kristiansen KI, Odsbu I, Dalhus B, Booth J, Rognes T, Skarstad K, Bjørås M (2013) 
Single transmembrane peptide DinQ modulates membrane-dependent activities. 
PLoS Genet. 2013;9(2):e1003260. doi: 10.1371/journal.pgen.1003260. Epub 2013 Feb 7. 

Herrmann D, Dahl JA, Lucas-Hahn A, Collas P, Niemann H (2013) 
Histone modifications and mRNA expression in the inner cell mass and trophectoderm of bovine blastocysts. Epigenetics. 2013 Mar;8(3):281-9. doi: 10.4161/epi.23899. Epub 2013 Feb 13. 

Doorn J, Fernandes HA, Le BQ, van de Peppel J, van Leeuwen JP, De Vries MR, Aref Z, Quax PH, Myklebost O, Saris DB, van Blitterswijk CA, de Boer J (2013) 
A small molecule approach to engineering vascularized tissue. 
Biomaterials. 2013 Apr;34(12):3053-63. doi: 10.1016/j.biomaterials.2012.12.037. Epub 2013 Jan 29. 

Rolseth V, Krokeide SZ, Kunke D, Neurauter CG, Suganthan R, Sejersted Y, Hildrestrand GA, Bjørås M, Luna L (2013) 
Loss of Neil3, the major DNA glycosylase activity for removal of hydantoins in single stranded DNA, reduces cellular proliferation and sensitizes cells to genotoxic stress. Biochim Biophys Acta. 2013 May;1833(5):1157-64. doi: 10.1016/j.bbamcr.2012.12.024. Epub 2013 Jan 7. 

Cornez I, Joel M, Taskén K, Langmoen IA, Glover JC, Berge T (2013) 
EGF signalling and rapamycin-mediated mTOR inhibition in glioblastoma multiforme evaluated by phospho-specific flow cytometry.
J Neurooncol. 2013 Mar;112(1):49-57. doi: 10.1007/s11060-012-1035-9. Epub 2013 Jan 9. 

Jobert L, Skjeldam HK, Dalhus B, Galashevskaya A, Vågbø CB, Bjørås M, Nilsen H (2013) 
The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control. Mol Cell. 2013 Jan 24;49(2):339-45. doi: 10.1016/j.molcel.2012.11.010. Epub 2012 Dec 13. 

Dalhus B, Nilsen L, Korvald H, Huffman J, Forstrøm RJ, McMurray CT, Alseth I, Tainer JA, Bjørås M (2013) Sculpting of DNA at abasic sites by DNA glycosylase homolog mag2. 
Structure. 2013 Jan 8;21(1):154-66. doi: 10.1016/j.str.2012.11.004. Epub 2012 Dec 13. 

Midttun Ø, Kvalheim G, Ueland PM (2013) 
High-throughput, low-volume, multianalyte quantification of plasma metabolites related to one-carbon metabolism using HPLC-MS/MS. 
Anal Bioanal Chem. 2013 Feb;405(6):2009-17. doi: 10.1007/s00216-012-6602-6. Epub 2012 Dec 13. 

Delbarre E, Ivanauskiene K, Küntziger T, Collas P (2013) 
DAXX-dependent supply of soluble (H3.3-H4) dimers to PML bodies pending deposition into chromatin. 
Genome Res. 2013 Mar;23(3):440-51. doi: 10.1101/gr.142703.112. Epub 2012 Dec 5. 

Zheng G, Dahl JA, Niu Y, Fedorcsak P, Huang CM, Li CJ, Vågbø CB, Shi Y, Wang WL, Song SH, Lu Z, Bosmans RP, Dai Q, Hao YJ, Yang X, Zhao WM, Tong WM, Wang XJ, Bogdan F, Furu K, Fu Y, Jia G, Zhao X, Liu J, Krokan HE, Klungland A, Yang YG, He C (2013) 
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. 
Mol Cell. 2013 Jan 10;49(1):18-29. doi: 10.1016/j.molcel.2012.10.015. Epub 2012 Nov 21. 

Ohnstad HO, Castro R, Sun J, Heintz KM, Vassilev LT, Bjerkehagen B, Kresse SH, Meza-Zepeda LA, Myklebost O (2013) 
Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma. 
Cancer. 2013 Mar 1;119(5):1013-22. doi: 10.1002/cncr.27837. Epub 2012 Nov 16. 

Boulland JL, Mastrangelopoulou M, Boquest AC, Jakobsen R, Noer A, Glover JC, Collas P (2013) 
Epigenetic regulation of nestin expression during neurogenic differentiation of adipose tissue stem cells. Stem Cells Dev. 2013 Apr 1;22(7):1042-52. doi: 10.1089/scd.2012.0560. Epub 2012 Dec 21. 

Jung AY, Botma A, Lute C, Blom HJ, Ueland PM, Kvalheim G, Midttun Ø, Nagengast F, Steegenga W, Kampman E (2013) 
Plasma B vitamins and LINE-1 DNA methylation in leukocytes of patients with a history of colorectal adenomas. 
Mol Nutr Food Res. 2013 Apr;57(4):698-708. doi: 10.1002/mnfr.201200069. Epub 2012 Nov 7. 

Eide N, Hoifødt HK, Nesland JM, Faye RS, Qvale GA, Faber RT, Jebsen P, Kvalheim G, Fodstad O (2013) Disseminated tumour cells in bone marrow of patients with uveal melanoma. 
Acta Ophthalmol. 2013 Jun;91(4):343-8. doi: 10.1111/j.1755-3768.2012.02449.x. Epub 2012 May 25. 

Haug K, Azqueta A, Johnsen-Soriano S, Shahdadfar A, Drolsum LK, Moe MC, Røger MT, Romero FJ, Collins AR, Nicolaissen B (2013) 
Donor cornea transfer from Optisol GS to organ culture storage: a two-step procedure to increase donor tissue lifespan. Acta Ophthalmol. 2013 May;91(3):219-25. doi: 10.1111/j.1755-3768.2012.02390.x. Epub 2012

2012:

Erik O. Johnsen,Rebecca C. Frøen, Réka Albert, Bente K. Omdal, Zsolt Sarang, András Berta,
Bjørn Nicolaissen, Goran Petrovski, Morten C. Moe
Activation of neural progenitor cells in human eyes with proliferative vitreoretinopathy
Experimental Eye Research 98 (2012) 28-36

Aboulghassem Shahdadfar, Kristiane Haug, Meeta Pathak, Liv Drolsum, Ole Kristoffer Olstad,
Erik O. Johnsen, Goran Petrovski, Morten C. Moe, Bjørn Nicolaissen
Ex vivo expanded autoloous limbal epithelial cells on amniotic membrane using a culture medium with human serum as single supplement
Experimental Eye Research 97 (2012)1-9

2011:

Adam B. Robertson, John A. Dahl, Cathrine B. Vågbø, Pankaj Tripathi, Hans E. Krokan and Arne Klungland
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA
Nucleic Acids Research, 2011, 1-10

Petter Strømme, Kostantin Dobrenis, Roy V. Sillitoe, Maria Gulinello, Nafeeza F. Ali, Cristin Davidson, Matthew C. Micsenyi, Gloria Stephney, Linda Ellevog, Arne Klungland and Steven U. Walkley
X-linked Angelman-like syndrome caused by Slc9a6 knockout in mica exhibits evidence of endosomal-lysosomal dysfunction
Brain 2011: 134; 3369-3383

Rebecca C. Frøen, Erik O. Johnsen, Goran Petrovski, Erika Berényi, Andrea Facskó, András Berta, Bjørn Nicolaissen and Morten C. Moe
Pigment epithelial cells isolated from human peripheral iridectomies have limited properties of retinal stem cells
Acta Ophthalmologica, 2011 

Jan O Gordeladze, Janne E Reseland, Tommy A Karlsen, Rune B Jakobsen, Lars Engebretsen, Ståle P Lyngstadaas, Christian Jorgensen, Hans Yssel and Jan E Brinchmann
Bone and Cartilage from Stem Cells: Growth Optimalization and Stabilization of Cell Phenotypes
Regenerative Medicine and Tissue Engineering, Cells and Briomaterials
INTECH: Edited by Daniel Eberli, ISBN 978-953-307-663-8 Aug 2011 

Jan Otto Beitnes, Ketil Lunde1, Jan E Brinchmann and Svend Aakhus
Stem cells for cardiac repair in acute myocardial infarction
Expert Reviews Cardiovasc. Ther. 9(8), 2011; 1015-1025

Krisztina Szöke, Karen Johanne Beckstrøm and Jan E. Brinchmann
Human adipose tissue as a source of cells with angiogenic potential
Cell Transplantation, CT-0318 2011

Yngve Sejersted, Gunn A. Hildrestrand, David Kunke, Veslemøy Rolseth, Silje Z. Krokeide, Christine G. Neurauter, Rajikala Suganthan, Monica Atneosen-Åsegg, Aaron M. Fleming, Ola D. Saugstad, Cynthia J. Burrows, Luisa Luna and Magnar Bjørås
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia
PNAS May 27, 2011

Sarah Roxana Herlofsen, Axel M. Küchler, Jan Egil Melvik and Jan E. Brinchmann
Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells in Self-Gelling Alginate Discs
Reveals Novel Chondrogenic Signature Gene Clusters
Tissue Engineering: Part A, Volume 17, Numbers 7 and 8, 2011

Shivali Duggal and Jan E Brinchmann
Importance of serum source for the in vitro replicative senescence of human bone marrow derived mesenchymal stem cells
Journal of Cellular Physiology, 2011

Tommy A. Karlsen, Aboulghassem Shahdadfar and Jan E. Brinchmann
Human Primary Articular Chondrocytes, Chondroblasts-Like Cells, and Dedifferentiated Chondrocytes: Differences
in Gene, MicroRNA, and Protein Expression and Phenotype
Tissue Engineering: Part C, Volume 17, Number 2, 2011 

Wei Wang, Ying Esbensen, David Kunke, Rajikala Suganthan, Lyudmila Rachek, Magnar Bjørås and Lars Eide
Mitochondrial DNA Damage Level Determines Neural Stem Cell Differentiation Fate
The Journal of Neuroscience, June 29, 2011; 9746-9751 

Erwin van den Born, Cathrine B. Vågbø, Lene Songe-Møller, Vibeke Leihne, Guro F. Lien, Grazyna Leszczynska, Andrzej Malkiewicz, Hans E. Krokan, Finn Kirpekar, Arne Klungland and Pål Ø. Falnes
ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA
Nature Communication, February 2011