Harald Weedon-Fekjær

  • Senior researcher (Statistician); PhD
  • +47 975 70 081

Professional interests:

Statistical modeling and simulation, applied statistics, statistical computing and software, teaching of statistics

Ongoing research topics:

  • Modelling of breast cancer progression and mammography screening
  • Evaluating of cancer screening
  • Breast cancer epidemiology
    (= statistical modelling and evidence synthesis applied to breast cancer)

Selected publications:

  1. Heggland T, Vatten LJ, Opdahl S, Weedon-Fekjær H (2023)
    Non-progressive breast carcinomas detected at mammography screening: a population study
    Breast Cancer Res, 25 (1), 80
  2. Weedon-Fekjær H, Romundstad PR, Vatten LJ (2014)
    Modern mammography screening and breast cancer mortality: population study
    BMJ, 348, g3701
  3. Weedon-Fekjær H, Bakken K, Vatten LJ, Tretli S (2012)
    Understanding recent trends in incidence of invasive breast cancer in Norway: age-period-cohort analysis based on registry data on mammography screening and hormone treatment use
    BMJ, 344, e299
  4. Weedon-Fekjaer H, Lindqvist BH, Vatten LJ, Aalen OO, Tretli S (2008)
    Breast cancer tumor growth estimated through mammography screening data
    Breast Cancer Res, 10 (3), R41
    (Among the journal’s 10 most accessed articles; Per 2012-08 no.6 with 34987 accesses)

Software packages:

Nordpred; Cancer incidence predictions,
http://www.kreftregisteret.no/software/nordpred

Addreg; Additive hazard regression survival analysis,
http://www.med.uio.no/imb/english/research/groups/causal-inference-methods/software/download/addreg-beta.html

Awards etc.:

  • ”Breast cancer tumor growth estimated through mammography screening data” (by Weedon-Fekjær et. al., 2008) was selected as article of the year 2008 by the Norwegian Epidemiological Association.

Research groups:

Part of US NCI-sponsored CISNET (The Cancer Intervention and Surveillance Modeling Network) consortium though Dana-Farber Cancer Institute / Harvard University, USA. See: http://cisnet.cancer.gov/

Teaching:

“MF9510E; Rates and poison regression”, Faculty of Medicine, University of Oslo


Curriculum vitae - Harald Weedon-Fekjær (open as PDF)

About Harald Weedon-Fekjær


 

Publications 2023

Fredwall SO, Linge J, de Vries O, Leinhard OD, Eggesbø HB, Weedon-Fekjær H, Petersson M, Widholm P, Månum G, Savarirayan R (2023)
Fat infiltration in the thigh muscles is associated with symptomatic spinal stenosis and reduced physical functioning in adults with achondroplasia
Orphanet J Rare Dis, 18 (1), 35
DOI 10.1186/s13023-023-02641-5, PubMed 36814258

Heggland T, Vatten LJ, Opdahl S, Weedon-Fekjær H (2023)
Non-progressive breast carcinomas detected at mammography screening: a population study
Breast Cancer Res, 25 (1), 80
DOI 10.1186/s13058-023-01682-9, PubMed 37403150

Henriksen HB, Berg HB, Andersen LF, Weedon-Fekjær H, Blomhoff R (2023)
Development of the Norwegian diet index and the Norwegian lifestyle index and evaluation in a national survey
Food Nutr Res, 67
DOI 10.29219/fnr.v67.9217, PubMed 37808205

Sverre E, Munkhaugen J, Kristiansen O, Weedon-Fekjaer H, Peersen K, Gjertsen E, Gullestad L, Bergan S, Husebye E, Vethe NT (2023)
Plasma concentration of atorvastatin metabolites correlates with low-density lipoprotein cholesterol reduction in patients with coronary heart disease
Pharmacol Res Perspect, 11 (3), e01089
DOI 10.1002/prp2.1089, PubMed 37186070

Torgersen KS, Sverre ECB, Weedon-Fekjær H, Andreassen OA, Munkhaugen J, Dammen T (2023)
Risk of recurrent cardiovascular events in coronary artery disease patients with Type D personality
Front Psychol, 14, 1119146
DOI 10.3389/fpsyg.2023.1119146, PubMed 37057178

Publications 2022

Faerden A, Rosenqvist C, Håkansson M, Strøm-Gundersen E, Stav Å, Svartsund J, Røssæg T, Davik N, Kvarstein E, Pedersen G, Dieset I, Nyrud AQ, Weedon-Fekjær H, Kistorp KM (2022)
Environmental Transformations Enhancing Dignity in an Acute Psychiatric Ward: Outcome of a User-Driven Service Design Project
HERD, 16 (2), 55-72
DOI 10.1177/19375867221136558, PubMed 36567605

Frøjd LA, Dammen T, Munkhaugen J, Weedon-Fekjær H, Nordhus IH, Papageorgiou C, Sverre E (2022)
Insomnia as a predictor of recurrent cardiovascular events in patients with coronary heart disease
Sleep Adv, 3 (1), zpac007
DOI 10.1093/sleepadvances/zpac007, PubMed 37193392

Heggland T, Vatten LJ, Opdahl S, Weedon-Fekjær H (2022)
Interpreting Breast Cancer Mortality Trends Related to Introduction of Mammography Screening: A Simulation Study
MDM Policy Pract, 7 (2), 23814683221131321
DOI 10.1177/23814683221131321, PubMed 36225967

LeBlanc M, Rueegg CS, Bekiroğlu N, Esterhuizen TM, Fagerland MW, Falk RS, Frøslie KF, Graf E, Heinze G, Held U, Holst R, Lange T, Mazumdar M, Myrberg IH, Posch M, Sergeant JC, Vach W, Vance EA, Weedon-Fekjaer H, Zucknick M (2022)
Statistical advising: Professional development opportunities for the biostatistician
Stat Med, 41 (5), 847-859
DOI 10.1002/sim.9290, PubMed 35194815

Publications 2021

Fredwall SO, Linge J, Leinhard OD, Kjønigsen L, Eggesbø HB, Weedon-Fekjær H, Lidal IB, Månum G, Savarirayan R, Tonstad S (2021)
Correction to: Cardiovascular risk factors and body composition in adults with achondroplasia
Genet Med, 23 (11), 2234
DOI 10.1038/s41436-021-01201-1, PubMed 34234305

Fredwall SO, Øverland B, Berdal H, Berg S, Weedon-Fekjær H, Lidal IB, Savarirayan R, Månum G (2021)
Obstructive sleep apnea in Norwegian adults with achondroplasia: a population-based study
Orphanet J Rare Dis, 16 (1), 156
DOI 10.1186/s13023-021-01792-7, PubMed 33827611

Publications 2020

Chootipongchaivat S, van Ravesteyn NT, Li X, Huang H, Weedon-Fekjær H, Ryser MD, Weaver DL, Burnside ES, Heckman-Stoddard BM, de Koning HJ, Lee SJ (2020)
Modeling the natural history of ductal carcinoma in situ based on population data
Breast Cancer Res, 22 (1), 53
DOI 10.1186/s13058-020-01287-6, PubMed 32460821

Fredwall SO, Linge J, Leinhard OD, Kjønigsen L, Eggesbø HB, Weedon-Fekjær H, Lidal IB, Månum G, Savarirayan R, Tonstad S (2020)
Cardiovascular risk factors and body composition in adults with achondroplasia
Genet Med, 23 (4), 732-739
DOI 10.1038/s41436-020-01024-6, PubMed 33204020

Fredwall SO, Steen U, de Vries O, Rustad CF, Eggesbø HB, Weedon-Fekjær H, Lidal IB, Savarirayan R, Månum G (2020)
High prevalence of symptomatic spinal stenosis in Norwegian adults with achondroplasia: a population-based study
Orphanet J Rare Dis, 15 (1), 123
DOI 10.1186/s13023-020-01397-6, PubMed 32450891

Fredwall SO, Steen U, de Vries O, Rustad CF, Eggesbø HB, Weedon-Fekjær H, Lidal IB, Savarirayan R, Månum G (2020)
Correction to: High prevalence of symptomatic spinal stenosis in Norwegian adults with achondroplasia: a population-based study
Orphanet J Rare Dis, 15 (1), 342
DOI 10.1186/s13023-020-01636-w, PubMed 33287852

Sverre E, Peersen K, Weedon-Fekjær H, Perk J, Gjertsen E, Husebye E, Gullestad L, Dammen T, Otterstad JE, Munkhaugen J (2020)
Preventable clinical and psychosocial factors predicted two out of three recurrent cardiovascular events in a coronary population
BMC Cardiovasc Disord, 20 (1), 61
DOI 10.1186/s12872-020-01368-6, PubMed 32024471

Villmones HC, Halland A, Stenstad T, Ulvestad E, Weedon-Fekjær H, Kommedal Ø (2020)
The cultivable microbiota of the human distal ileum
Clin Microbiol Infect, 27 (6), 912.e7-912.e13
DOI 10.1016/j.cmi.2020.08.021, PubMed 32835795

Weedon-Fekjær H, Li X, Lee S (2020)
Estimating the natural progression of non-invasive ductal carcinoma in situ breast cancer lesions using screening data
J Med Screen, 28 (3), 302-310
DOI 10.1177/0969141320945736, PubMed 32854582

Publications 2019

Henriksen TH, Abebe W, Amogne W, Getachew Y, Weedon-Fekjær H, Klein J, Woldeamanuel Y (2019)
Association between antimicrobial resistance among Enterobacteriaceae and burden of environmental bacteria in hospital acquired infections: analysis of clinical studies and national reports
Heliyon, 5 (7), e02054
DOI 10.1016/j.heliyon.2019.e02054, PubMed 31372534

Henriksen TH, Abebe W, Amogne W, Getachew Y, Weedon-Fekjær H, Klein J, Woldeamanuel Y (2019)
Corrigendum to "Association between antimicrobial resistance among Enterobacteriaceae and burden of environmental bacteria in hospital acquired infections: analysis of clinical studies and national reports" [Heliyon 5 (7) (July 2019) e02054]
Heliyon, 5 (8), e02383
DOI 10.1016/j.heliyon.2019.e02383, PubMed 31508528

Kjønigsen LJ, Harneshaug M, Fløtten AM, Karterud LK, Petterson K, Skjolde G, Eggesbø HB, Weedon-Fekjær H, Henriksen HB, Lauritzen PM (2019)
Reproducibility of semiautomated body composition segmentation of abdominal computed tomography: a multiobserver study
Eur Radiol Exp, 3 (1), 42
DOI 10.1186/s41747-019-0122-5, PubMed 31664547

Konst B, Weedon-Fekjaer H, Båth M (2019)
Image quality and radiation dose in planar imaging - Image quality figure of merits from the CDRAD phantom
J Appl Clin Med Phys, 20 (7), 151-159
DOI 10.1002/acm2.12649, PubMed 31152576

Publications 2018

Löffeler S, Halland A, Weedon-Fekjær H, Nikitenko A, Ellingsen CL, Haug ES (2018)
High Norwegian prostate cancer mortality: evidence of over-reporting
Scand J Urol, 52 (2), 122-128
DOI 10.1080/21681805.2017.1421260, PubMed 29325479

Majak GB, Reisæter AV, Weedon-Fekjær H, Henriksen T, Michelsen TM (2018)
The Effect of Pregnancy on the Long-term Risk of Graft Loss, Cardiovascular Disease, and Death in Kidney Transplanted Women in Norway: A Retrospective Cohort Study
Transplantation, 102 (9), e391-e396
DOI 10.1097/TP.0000000000002167, PubMed 29528968

Mandelblatt JS, Near AM, Miglioretti DL, Munoz D, Sprague BL, Trentham-Dietz A, Gangnon R, Kurian AW, Weedon-Fekjaer H, Cronin KA, Plevritis SK (2018)
Common Model Inputs Used in CISNET Collaborative Breast Cancer Modeling
Med Decis Making, 38 (1_suppl), 9S-23S
DOI 10.1177/0272989X17700624, PubMed 29554466

Sundby ØH, Irgens I, Høiseth LØ, Mathiesen I, Lundgaard E, Haugland H, Weedon-Fekjær H, Sundhagen JO, Sandbæk G, Hisdal J (2018)
Intermittent mild negative pressure applied to the lower limb in patients with spinal cord injury and chronic lower limb ulcers: a crossover pilot study
Spinal Cord, 56 (4), 372-381
DOI 10.1038/s41393-018-0080-4, PubMed 29497177

van Ravesteyn NT, van den Broek JJ, Li X, Weedon-Fekjær H, Schechter CB, Alagoz O, Huang X, Weaver DL, Burnside ES, Punglia RS, de Koning HJ, Lee SJ (2018)
Modeling Ductal Carcinoma In Situ (DCIS): An Overview of CISNET Model Approaches
Med Decis Making, 38 (1_suppl), 126S-139S
DOI 10.1177/0272989X17729358, PubMed 29554463

Westvik ÅS, Weedon-Fekjær H, Mæhlen J, Liestøl K (2018)
Evaluating different breast tumor progression models using screening data
BMC Cancer, 18 (1), 209
DOI 10.1186/s12885-018-4130-2, PubMed 29463227

Publications 2017

Sundby ØH, Høiseth LØ, Irgens I, Mathiesen I, Lundgaard E, Haugland H, Weedon-Fekjær H, Sundhagen JO, Sanbæk G, Hisdal J (2017)
Intermittent negative pressure applied to the lower limb increases foot macrocirculatory and microcirculatory blood flow pulsatility in people with spinal cord injury
Spinal Cord, 56 (4), 382-391
DOI 10.1038/s41393-017-0049-8, PubMed 29284796

Sundby ØH, Høiseth LØ, Mathiesen I, Weedon-Fekjær H, Sundhagen JO, Hisdal J (2017)
The acute effects of lower limb intermittent negative pressure on foot macro- and microcirculation in patients with peripheral arterial disease
PLoS One, 12 (6), e0179001
DOI 10.1371/journal.pone.0179001, PubMed 28591174

Trewin CB, Strand BH, Weedon-Fekjær H, Ursin G (2017)
Changing patterns of breast cancer incidence and mortality by education level over four decades in Norway, 1971-2009
Eur J Public Health, 27 (1), 160-166
DOI 10.1093/eurpub/ckw148, PubMed 28177482

Publications 2016

Boldingh MI, Maniaol AH, Brunborg C, Weedon-Fekjær H, Verschuuren JJ, Tallaksen CM (2016)
Increased risk for clinical onset of myasthenia gravis during the postpartum period
Neurology, 87 (20), 2139-2145
DOI 10.1212/WNL.0000000000003339, PubMed 27770065

Sundby ØH, Høiseth LØ, Mathiesen I, Jørgensen JJ, Weedon-Fekjær H, Hisdal J (2016)
Application of intermittent negative pressure on the lower extremity and its effect on macro- and microcirculation in the foot of healthy volunteers
Physiol Rep, 4 (17)
DOI 10.14814/phy2.12911, PubMed 27630148

Publications 2015

Berner K, Hall KS, Monge OR, Weedon-Fekjær H, Zaikova O, Bruland ØS (2015)
Prognostic factors and treatment results of high-grade osteosarcoma in norway: a scope beyond the "classical" patient
Sarcoma, 2015, 516843
DOI 10.1155/2015/516843, PubMed 25784831

Fosså SD, Dahl AA, Langhammer A, Weedon-Fekjær H (2015)
Cancer patients' participation in population-based health surveys: findings from the HUNT studies
BMC Res Notes, 8, 649
DOI 10.1186/s13104-015-1635-5, PubMed 26541408

Gangnon RE, Sprague BL, Stout NK, Alagoz O, Weedon-Fekjær H, Holford TR, Trentham-Dietz A (2015)
The contribution of mammography screening to breast cancer incidence trends in the United States: an updated age-period-cohort model
Cancer Epidemiol Biomarkers Prev, 24 (6), 905-12
DOI 10.1158/1055-9965.EPI-14-1286, PubMed 25787716

Löffeler S, Weedon-Fekjaer H, Wang-Hansen MS, Sebakk K, Hamre H, Haug ES, Fosså SD (2015)
"Natural course" of disease in patients with metastatic castrate-resistant prostate cancer: Survival and prognostic factors without life-prolonging treatment
Scand J Urol, 49 (6), 440-445
DOI 10.3109/21681805.2015.1059881, PubMed 26139461

Zaikova O, Sundby Hall K, Styring E, Eriksson M, Trovik CS, Bergh P, Bjerkehagen B, Skorpil M, Weedon-Fekjaer H, Bauer HC (2015)
Referral patterns, treatment and outcome of high-grade malignant bone sarcoma in Scandinavia--SSG Central Register 25 years' experience
J Surg Oncol, 112 (8), 853-60
DOI 10.1002/jso.24074, PubMed 26482729

Publications 2014

Solheim O, Gershenson DM, Tropé CG, Rokkones E, Sun CC, Weedon-Fekjaer H, Fosså SD (2014)
Prognostic factors in malignant ovarian germ cell tumours (The Surveillance, Epidemiology and End Results experience 1978-2010)
Eur J Cancer, 50 (11), 1942-50
DOI 10.1016/j.ejca.2014.03.288, PubMed 24857045

Weedon-Fekjær H, Romundstad PR, Vatten LJ (2014)
Modern mammography screening and breast cancer mortality: population study
BMJ, 348, g3701
DOI 10.1136/bmj.g3701, PubMed 24951459

Publications 2012

Weedon-Fekjær H, Bakken K, Vatten LJ, Tretli S (2012)
Understanding recent trends in incidence of invasive breast cancer in Norway: age-period-cohort analysis based on registry data on mammography screening and hormone treatment use
BMJ, 344, e299
DOI 10.1136/bmj.e299, PubMed 22290099

Publications 2011

Weedon-Fekjær H (2011)
Effectiveness of population-based service screening with mammography for women ages 40 to 49 years: evaluation of the Swedish Mammography Screening in Young Women (SCRY) Cohort
Cancer, 118 (4), 1169; author reply 1170-1
DOI 10.1002/cncr.26163, PubMed 21766290

Publications 2010

Weedon-Fekjaer H, Tretli S, Aalen OO (2010)
Estimating screening test sensitivity and tumour progression using tumour size and time since previous screening
Stat Methods Med Res, 19 (5), 507-27
DOI 10.1177/0962280209359860, PubMed 20356856

Publications 2009

Weedon-Fekjaer H, Sørum R, Brenn MK (2009)
Hormone therapy use may explain recent results regarding tumor regression
Arch Intern Med, 169 (10), 996-7
DOI 10.1001/archinternmed.2009.90, PubMed 19468094

Publications 2008

Weedon-Fekjaer H, Lindqvist BH, Vatten LJ, Aalen OO, Tretli S (2008)
Breast cancer tumor growth estimated through mammography screening data
Breast Cancer Res, 10 (3), R41
DOI 10.1186/bcr2092, PubMed 18466608

Weedon-Fekjaer H, Lindqvist BH, Vatten LJ, Aalen OO, Tretli S (2008)
Estimating mean sojourn time and screening sensitivity using questionnaire data on time since previous screening
J Med Screen, 15 (2), 83-90
DOI 10.1258/jms.2008.007071, PubMed 18573776

Publications 2006

Andersson G, Noack T, Seierstad A, Weedon-Fekjaer H (2006)
The demographics of same-sex marriages in Norway and Sweden
Demography, 43 (1), 79-98
DOI 10.1353/dem.2006.0001, PubMed 16579209

Fosen J, Borgan O, Weedon-Fekjaer H, Aalen OO (2006)
Dynamic analysis of recurrent event data using the additive hazard model
Biom J, 48 (3), 381-98
DOI 10.1002/bimj.200510217, PubMed 16845903

Wibe A, Carlsen E, Dahl O, Tveit KM, Weedon-Fekjaer H, Hestvik UE, Wiig JN, Norwegian Rectal Cancer Group (2006)
Nationwide quality assurance of rectal cancer treatment
Colorectal Dis, 8 (3), 224-9
DOI 10.1111/j.1463-1318.2005.00924.x, PubMed 16466564

Publications 2005

Møller B, Weedon-Fekjaer H, Hakulinen T, Tryggvadóttir L, Storm HH, Talbäck M, Haldorsen T (2005)
The influence of mammographic screening on national trends in breast cancer incidence
Eur J Cancer Prev, 14 (2), 117-28
DOI 10.1097/00008469-200504000-00007, PubMed 15785315

Møller B, Weedon-Fekjaer H, Haldorsen T (2005)
Empirical evaluation of prediction intervals for cancer incidence
BMC Med Res Methodol, 5, 21
DOI 10.1186/1471-2288-5-21, PubMed 15949034

Noack T, Seierstad A, Weedon-Fekjaer H (2005)
A demographic analysis of registered partnerships (legal same-sex unions): The case of Norway
Eur. J. Popul.-Rev. Eur. Demogr., 21 (1), 89-109
DOI 10.1007/s10680-005-3626-z

Weedon-Fekjaer H, Vatten LJ, Aalen OO, Lindqvist B, Tretli S (2005)
Estimating mean sojourn time and screening test sensitivity in breast cancer mammography screening: new results
J Med Screen, 12 (4), 172-8
DOI 10.1258/096914105775220732, PubMed 16417693

Publications 2004

Aalen OO, Fosen J, Weedon-Fekjaer H, Borgan O, Husebye E (2004)
Dynamic analysis of multivariate failure time data
Biometrics, 60 (3), 764-73
DOI 10.1111/j.0006-341X.2004.00227.x, PubMed 15339300