The main aim of our research is to understand mechanisms regulating cholangitis with a clear focus on immunology and the interaction of the immune system with the microbiome. Recently we have increased our use of techniques from regenerative medicine and we have also started using sequencing-based methodologies. Together with patient material, animal models and in vitro assays these additional techniques give us a comprehensive and complete scientific toolbox for achieving our aims.
Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis
Hepatol Commun, 6 (9), 2538-2550
Risk of hepato-pancreato-biliary cancer is increased by primary sclerosing cholangitis in patients with inflammatory bowel disease: A population-based cohort study
United European Gastroenterol J, 10 (2), 212-224
Impact of delayed type hypersensitivity arthritis on development of heart failure by aortic constriction in mice
PLoS One, 17 (1), e0262821