Publications

Publications 2024

  1. Brugger M, Lauri A, Zhen Y, Gramegna LL, Zott B, Sekulić N, Fasano G, Kopajtich R, Cordeddu V, Radio FC, Mancini C, Pizzi S, Paradisi G, Zanni G, Vasco G, Carrozzo R, Palombo F, Tonon C, Lodi R, La Morgia C, Arelin M, Blechschmidt C, Finck T, Sørensen V, Kreiser K et al. (2024)
    Bi-allelic variants in SNF8 cause a disease spectrum ranging from severe developmental and epileptic encephalopathy to syndromic optic atrophy
    Am J Hum Genet, 111 (3), 594-613
    DOI 10.1016/j.ajhg.2024.02.005, PubMed 38423010
  2. Casey NP, Kleinmanns K, Forcados C, Gelebart PF, Joaquina S, Lode M, Benard E, Kaveh F, Caulier B, Helgestad Gjerde C, García de Jalón E, Warren DJ, Lindemann K, Rokkones E, Davidson B, Myhre MR, Kvalheim G, Bjørge L, McCormack E, Inderberg EM, Wälchli S (2024)
    Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16
    J Immunother Cancer, 12 (4)
    DOI 10.1136/jitc-2023-008179, PubMed 38604812
  3. Caulier B, Joaquina S, Gelebart P, Dowling TH, Kaveh F, Thomas M, Tandaric L, Wernhoff P, Katyayini NU, Wogsland C, Gjerstad ME, Fløisand Y, Kvalheim G, Marr C, Kobold S, Enserink JM, Gjertsen BT, McCormack E, Inderberg EM, Wälchli S (2024)
    CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
    Cell Rep Med, 5 (6), 101572
    DOI 10.1016/j.xcrm.2024.101572, PubMed 38754420
  4. Corrales J, Ramos-Alonso L, González-Sabín J, Ríos-Lombardía N, Trevijano-Contador N, Engen Berg H, Sved Skottvoll F, Moris F, Zaragoza O, Chymkowitch P, Garcia I, Enserink JM (2024)
    Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole
    Microbiol Spectr, 12 (2), e0259423
    DOI 10.1128/spectrum.02594-23, PubMed 38230926
  5. Fuentes-Martín R, Ayuda-Durán P, Hanes R, Gallego-Yerga L, Wolterinck L, Enserink JM, Álvarez R, Peláez R (2024)
    Promising anti-proliferative indolic benzenesulfonamides alter mechanisms with sulfonamide nitrogen substituents
    Eur J Med Chem, 275, 116617
    DOI 10.1016/j.ejmech.2024.116617, PubMed 38959729
  6. Hamid MHBA, Cespedes PF, Jin C, Chen JL, Gileadi U, Antoun E, Liang Z, Gao F, Teague R, Manoharan N, Maldonado-Perez D, Khalid-Alham N, Cerundolo L, Ciaoca R, Hester SS, Pinto-Fernández A, Draganov SD, Vendrell I, Liu G, Yao X, Kvalvaag A, Dominey-Foy DCC, Nanayakkara C, Kanellakis N, Chen YL et al. (2024)
    Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity
    Nat Immunol, 25 (5), 834-846
    DOI 10.1038/s41590-024-01802-3, PubMed 38561495
  7. Kvalvaag A, Dustin ML (2024)
    Clathrin controls bidirectional communication between T cells and antigen presenting cells
    Bioessays, 46 (4), e2300230
    DOI 10.1002/bies.202300230, PubMed 38412391
  8. Llorente A, Brokāne A, Mlynska A, Puurand M, Sagini K, Folkmane S, Hjorth M, Martin-Gracia B, Romero S, Skorinkina D, Čampa M, Cešeiko R, Romanchikova N, Kļaviņa A, Käämbre T, Linē A (2024)
    From sweat to hope: The role of exercise-induced extracellular vesicles in cancer prevention and treatment
    J Extracell Vesicles, 13 (8), e12500
    DOI 10.1002/jev2.12500, PubMed 39183543
  9. Nähse V, Stenmark H, Schink KO (2024)
    Omegasomes control formation, expansion, and closure of autophagosomes
    Bioessays, 46 (6), e2400038
    DOI 10.1002/bies.202400038, PubMed 38724256
  10. Philips EA, Liu J, Kvalvaag A, Mørch AM, Tocheva AS, Ng C, Liang H, Ahearn IM, Pan R, Luo CC, Leithner A, Qin Z, Zhou Y, Garcia-España A, Mor A, Littman DR, Dustin ML, Wang J, Kong XP (2024)
    Transmembrane domain-driven PD-1 dimers mediate T cell inhibition
    Sci Immunol, 9 (93), eade6256
    DOI 10.1126/sciimmunol.ade6256, PubMed 38457513
  11. Radulovic M, Stenmark H (2024)
    Lysophagy prevents neurotoxic aggregate transmission
    Proc Natl Acad Sci U S A, 121 (3), e2321181121
    DOI 10.1073/pnas.2321181121, PubMed 38190545
  12. Sandvig K, Iversen TG, Skotland T (2024)
    Entry of nanoparticles into cells and tissues: status and challenges
    Beilstein J Nanotechnol, 15, 1017-1029
    DOI 10.3762/bjnano.15.83, PubMed 39161463
  13. Skotland T, Ekroos K, McDonald J, Ahrends R, Liebisch G, Sandvig K (2024)
    Pitfalls in lipid mass spectrometry of mammalian samples - a brief guide for biologists
    Nat Rev Mol Cell Biol, 25 (10), 759-760
    DOI 10.1038/s41580-024-00758-4, PubMed 38951702
  14. Teles-Reis J, Jain A, Liu D, Khezri R, Micheli S, Gomez AA, Dillard C, Rusten TE (2024)
    EyaHOST, a modular genetic system for investigation of intercellular and tumor-host interactions in Drosophila melanogaster
    bioRxiv
    DOI 10.1101/2024.09.06.611647, PubMed 39314415
  15. Theriot JA, Simonsen A, Tolić I, Leonetti MD, Mayor S, Bassereau P, Paluch EK, Han J, Covert MW, Mizushima N, Reck-Peterson S, Strasser A, Cheeseman I (2024)
    Cell biology is…
    Cell, 187 (2), 219-224
    DOI 10.1016/j.cell.2023.12.020, PubMed 38242078
  16. Totland MZ, Knudsen LM, Rasmussen NL, Omori Y, Sørensen V, Elster VCW, Stenersen JM, Larsen M, Jensen CL, Zickfeldt Lade AA, Bruusgaard E, Basing S, Kryeziu K, Brech A, Aasen T, Lothe RA, Leithe E (2024)
    The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation
    Cell Mol Life Sci, 81 (1), 171
    DOI 10.1007/s00018-024-05165-8, PubMed 38597989
  17. Valsalakumari R, Pandya AD, Prasmickaite L, Kvalvaag A, Myrann AG, Åslund AKO, Kjos MS, Fontecha-Cuenca C, Haroon HB, Ribeiro ARS, Horejs-Hoeck J, Moghimi SM, Mørch Ý, Skotland T, Sandvig K, Mælandsmo GM, Iversen TG (2024)
    Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
    Int J Nanomedicine, 19, 3009-3029
    DOI 10.2147/IJN.S450283, PubMed 38562610
  18. Wang HL, Siow R, Schmauck-Medina T, Zhang J, Sandset PM, Filshie C, Lund Ø, Partridge L, Bergersen LH, Juel Rasmussen L, Palikaras K, Sotiropoulos I, Storm-Mathisen J, Rubinsztein DC, Spillantini MG, De Zeeuw CI, Watne LO, Vyhnalek M, Veverova K, Liang KX, Tavernarakis N, Bohr VA, Yokote K, Saarela J, Nilsen H et al. (2024)
    Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies
    J Gerontol A Biol Sci Med Sci, 79 (4)
    DOI 10.1093/gerona/glae029, PubMed 38289789
  19. Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S et al. (2024)
    Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
    J Extracell Vesicles, 13 (2), e12404
    DOI 10.1002/jev2.12404, PubMed 38326288
  20. Wenzel EM, Pedersen NM, Elfmark LA, Wang L, Kjos I, Stang E, Malerød L, Brech A, Stenmark H, Raiborg C (2024)
    Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
    Nat Commun, 15 (1), 1277
    DOI 10.1038/s41467-024-45558-8, PubMed 38341434
  21. Wu C, Gunnarsson EB, Myklebust EM, Köhn-Luque A, Tadele DS, Enserink JM, Frigessi A, Foo J, Leder K (2024)
    Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data
    PLoS Comput Biol, 20 (3), e1011888
    DOI 10.1371/journal.pcbi.1011888, PubMed 38446830
  22. Zhen Y, Stenmark H (2024)
    A dual-purpose fusion complex in autophagy
    Cell Res, 34 (3), 183-184
    DOI 10.1038/s41422-023-00925-w, PubMed 38228880
  23. Zhen Y, Stenmark H (2024)
    Exosome regulation by Rubicon in ageing
    Nat Cell Biol, 26 (9), 1380-1381
    DOI 10.1038/s41556-024-01482-z, PubMed 39174741

Publications 2023

  1. Al Outa A, Hicks S, Thambawita V, Andresen S, Enserink JM, Halvorsen P, Riegler MA, Knævelsrud H (2023)
    CELLULAR, A Cell Autophagy Imaging Dataset
    Sci Data, 10 (1), 806
    DOI 10.1038/s41597-023-02687-x, PubMed 37973836
  2. Andersen AN, Brodersen AM, Ayuda-Durán P, Piechaczyk L, Tadele DS, Baken L, Fredriksen J, Stoksflod M, Lenartova A, Fløisand Y, Skånland SS, Enserink JM (2023)
    Clinical forecasting of acute myeloid leukemia using ex vivo drug-sensitivity profiling
    Cell Rep Methods, 3 (12), 100654
    DOI 10.1016/j.crmeth.2023.100654, PubMed 38065095
  3. Ayuda-Durán P, Hermansen JU, Giliberto M, Yin Y, Hanes R, Gordon S, Kuusanmäki H, Brodersen AM, Andersen AN, Taskén K, Wennerberg K, Enserink JM, Skånland SS (2023)
    Standardized assays to monitor drug sensitivity in hematologic cancers
    Cell Death Discov, 9 (1), 435
    DOI 10.1038/s41420-023-01722-5, PubMed 38040674
  4. Bajo-Santos C, Brokāne A, Zayakin P, Endzeliņš E, Soboļevska K, Belovs A, Jansons J, Sperga M, Llorente A, Radoviča-Spalviņa I, Lietuvietis V, Linē A (2023)
    Plasma and urinary extracellular vesicles as a source of RNA biomarkers for prostate cancer in liquid biopsies
    Front Mol Biosci, 10, 980433
    DOI 10.3389/fmolb.2023.980433, PubMed 36818049
  5. Capera J, Jainarayanan A, Navarro-Pérez M, Valvo S, Demetriou P, Depoil D, Estadella I, Kvalvaag A, Felce JH, Felipe A, Dustin ML (2023)
    Dynamics and spatial organization of Kv1.3 at the immunological synapse of human CD4+ T cells
    Biophys J, 123 (15), 2271-2281
    DOI 10.1016/j.bpj.2023.08.011, PubMed 37596785
  6. Casey NP, Klee CH, Fåne A, Caulier B, Graczyk-Jarzynka A, Krawczyk M, Fidyt K, Josefsson SE, Köksal H, Dillard P, Patkowska E, Firczuk M, Smeland EB, Winiarska M, Myklebust JH, Inderberg EM, Wälchli S (2023)
    Efficient chimeric antigen receptor targeting of a central epitope of CD22
    J Biol Chem, 299 (7), 104883
    DOI 10.1016/j.jbc.2023.104883, PubMed 37269947
  7. Chen Y, He L, Ianevski A, Ayuda-Durán P, Potdar S, Saarela J, Miettinen JJ, Kytölä S, Miettinen S, Manninen M, Heckman CA, Enserink JM, Wennerberg K, Aittokallio T (2023)
    Robust scoring of selective drug responses for patient-tailored therapy selection
    Nat Protoc, 19 (1), 60-82
    DOI 10.1038/s41596-023-00903-x, PubMed 37996540
  8. Clement D, Szabo EK, Krokeide SZ, Wiiger MT, Vincenti M, Palacios D, Chang YT, Grimm C, Patel S, Stenmark H, Brech A, Majhi RK, Malmberg KJ (2023)
    The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk
    J Immunol, 211 (9), 1348-1358
    DOI 10.4049/jimmunol.2300406, PubMed 37737664
  9. Davies EM, Mitchell CA, Stenmark HA (2023)
    Phosphoinositides in New Spaces
    Cold Spring Harb Perspect Biol, 15 (9)
    DOI 10.1101/cshperspect.a041406, PubMed 37463718
  10. Elfmark LA, Wenzel EM, Wang L, Pedersen NM, Stenmark H, Raiborg C (2023)
    Protrudin-mediated ER-endosome contact sites promote phagocytosis
    Cell Mol Life Sci, 80 (8), 216
    DOI 10.1007/s00018-023-04862-0, PubMed 37468729
  11. Hanes R, Ayuda-Durán P, Rønneberg L, Nakken S, Hovig E, Zucknick M, Enserink JM (2023)
    screenwerk: a modular tool for the design and analysis of drug combination screens
    Bioinformatics, 39 (1)
    DOI 10.1093/bioinformatics/btac840, PubMed 36573326
  12. Hessvik NP, Sagini K, Romero S, Ramirez-Garrastacho M, Rodriguez M, Tutturen AEV, Kvalvaag A, Stang E, Brech A, Sandvig K, Llorente A (2023)
    siRNA screening reveals that SNAP29 contributes to exosome release
    Cell Mol Life Sci, 80 (7), 177
    DOI 10.1007/s00018-023-04822-8, PubMed 37285022
  13. Holme B, Bjørnerud B, Pedersen NM, de la Ballina LR, Wesche J, Haugsten EM (2023)
    Automated tracking of cell migration in phase contrast images with CellTraxx
    Sci Rep, 13 (1), 22982
    DOI 10.1038/s41598-023-50227-9, PubMed 38151514
  14. Joaquina S, Forcados C, Caulier B, Inderberg EM, Wälchli S (2023)
    Determination of CAR T cell metabolism in an optimized protocol
    Front Bioeng Biotechnol, 11, 1207576
    DOI 10.3389/fbioe.2023.1207576, PubMed 37409169
  15. Johannessen JA, Formica M, Haukeland ALC, Bråthen NR, Al Outa A, Aarsund M, Therrien M, Enserink JM, Knævelsrud H (2023)
    The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae
    iScience, 26 (10), 107726
    DOI 10.1016/j.isci.2023.107726, PubMed 37720104
  16. Kaur N, Carlsson SR, Lystad AH (2023)
    The separate axes of TECPR1 and ATG16L1 in CASM
    Autophagy, 20 (1), 214-215
    DOI 10.1080/15548627.2023.2255462, PubMed 37676042
  17. Kaur N, de la Ballina LR, Haukaas HS, Torgersen ML, Radulovic M, Munson MJ, Sabirsh A, Stenmark H, Simonsen A, Carlsson SR, Lystad AH (2023)
    TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
    EMBO J, 42 (17), e113105
    DOI 10.15252/embj.2022113105, PubMed 37409525
  18. Kvalvaag A, Valvo S, Céspedes PF, Saliba DG, Kurz E, Korobchevskaya K, Dustin ML (2023)
    Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse
    Proc Natl Acad Sci U S A, 120 (6), e2211368120
    DOI 10.1073/pnas.2211368120, PubMed 36730202
  19. Köhn-Luque A, Myklebust EM, Tadele DS, Giliberto M, Schmiester L, Noory J, Harivel E, Arsenteva P, Mumenthaler SM, Schjesvold F, Taskén K, Enserink JM, Leder K, Frigessi A, Foo J (2023)
    Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data
    Cell Rep Methods, 3 (3), 100417
    DOI 10.1016/j.crmeth.2023.100417, PubMed 37056380
  20. Lampart A, Krowarsch D, Biadun M, Sorensen V, Szymczyk J, Sluzalska K, Wiedlocha A, Otlewski J, Zakrzewska M (2023)
    Intracellular FGF1 protects cells from apoptosis through direct interaction with p53
    Cell Mol Life Sci, 80 (10), 311
    DOI 10.1007/s00018-023-04964-9, PubMed 37783936
  21. Lamsal A, Andersen SB, Johansson I, Vietri M, Bokil AA, Kurganovs NJ, Rylander F, Bjørkøy G, Pettersen K, Giambelluca MS (2023)
    Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer
    Cell Commun Signal, 21 (1), 50
    DOI 10.1186/s12964-023-01062-y, PubMed 36882786
  22. Margadant F, Almsherqi Z, Xu X, Deng Y (2023)
    Optical Properties and Interference Effects of the Lens Mitochondrion
    Membranes (Basel), 13 (6)
    DOI 10.3390/membranes13060610, PubMed 37367815
  23. Migliano SM, Schultz SW, Wenzel EM, Takáts S, Liu D, Mørk S, Tan KW, Rusten TE, Raiborg C, Stenmark H (2023)
    Removal of hypersignaling endosomes by simaphagy
    Autophagy, 20 (4), 769-791
    DOI 10.1080/15548627.2023.2267958, PubMed 37840274
  24. Nunzi E, Mezzasoma L, Bellezza I, Zelante T, Orvietani P, Coata G, Giardina I, Sagini K, Manni G, Di Michele A, Gargaro M, Talesa VN, Di Renzo GC, Fallarino F, Romani R (2023)
    Microbiota-Associated HAF-EVs Regulate Monocytes by Triggering or Inhibiting Inflammasome Activation
    Int J Mol Sci, 24 (3)
    DOI 10.3390/ijms24032527, PubMed 36768851
  25. Nähse V, Raiborg C, Tan KW, Mørk S, Torgersen ML, Wenzel EM, Nager M, Salo VT, Johansen T, Ikonen E, Schink KO, Stenmark H (2023)
    ATPase activity of DFCP1 controls selective autophagy
    Nat Commun, 14 (1), 4051
    DOI 10.1038/s41467-023-39641-9, PubMed 37422481
  26. Nähse V, Schink KO, Stenmark H (2023)
    ATPase-regulated autophagosome biogenesis
    Autophagy, 20 (1), 218-219
    DOI 10.1080/15548627.2023.2255967, PubMed 37722386
  27. Perdreau-Dahl H, Lipsett DB, Frisk M, Kermani F, Carlson CR, Brech A, Shen X, Bergan-Dahl A, Hou Y, Tuomainen T, Tavi P, Jones PP, Lunde M, Wasserstrom JA, Laporte J, Ullrich ND, Christensen G, Morth JP, Louch WE (2023)
    BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes
    Circ Res, 132 (11), e188-e205
    DOI 10.1161/CIRCRESAHA.122.321732, PubMed 37139790
  28. Pust S, Brech A, Wegner CS, Stenmark H, Haglund K (2023)
    Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis
    Cell Mol Life Sci, 80 (8), 235
    DOI 10.1007/s00018-023-04864-y, PubMed 37523003
  29. Ramos-Alonso L, Holland P, Le Gras S, Zhao X, Jost B, Bjørås M, Barral Y, Enserink JM, Chymkowitch P (2023)
    Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
    Proc Natl Acad Sci U S A, 120 (4), e2210593120
    DOI 10.1073/pnas.2210593120, PubMed 36656860
  30. Sagini K, Urbanelli L, Buratta S, Emiliani C, Llorente A (2023)
    Lipid Biomarkers in Liquid Biopsies: Novel Opportunities for Cancer Diagnosis
    Pharmaceutics, 15 (2)
    DOI 10.3390/pharmaceutics15020437, PubMed 36839759
  31. Sandoz PA, Kuhnigk K, Szabo EK, Thunberg S, Erikson E, Sandström N, Verron Q, Brech A, Watzl C, Wagner AK, Alici E, Malmberg KJ, Uhlin M, Önfelt B (2023)
    Modulation of lytic molecules restrain serial killing in γδ T lymphocytes
    Nat Commun, 14 (1), 6035
    DOI 10.1038/s41467-023-41634-7, PubMed 37758698
  32. Sarmento MJ, Llorente A, Petan T, Khnykin D, Popa I, Nikolac Perkovic M, Konjevod M, Jaganjac M (2023)
    The expanding organelle lipidomes: current knowledge and challenges
    Cell Mol Life Sci, 80 (8), 237
    DOI 10.1007/s00018-023-04889-3, PubMed 37530856
  33. Skotland T, Llorente A, Sandvig K (2023)
    Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?
    Cold Spring Harb Perspect Biol, 15 (8)
    DOI 10.1101/cshperspect.a041415, PubMed 37277192
  34. Stonyte V, Mastrangelopoulou M, Timmer R, Lindbergsengen L, Vietri M, Campsteijn C, Grallert B (2023)
    The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity
    EMBO Rep, 24 (8), e56100
    DOI 10.15252/embr.202256100, PubMed 37291955
  35. Tislevoll BS, Hellesøy M, Fagerholt OHE, Gullaksen SE, Srivastava A, Birkeland E, Kleftogiannis D, Ayuda-Durán P, Piechaczyk L, Tadele DS, Skavland J, Baliakas P, Hovland R, Andresen V, Seternes OM, Tvedt THA, Aghaeepour N, Gavasso S, Porkka K, Jonassen I, Fløisand Y, Enserink J, Blaser N, Gjertsen BT (2023)
    Early response evaluation by single cell signaling profiling in acute myeloid leukemia
    Nat Commun, 14 (1), 115
    DOI 10.1038/s41467-022-35624-4, PubMed 36611026
  36. Tislevoll BS, Hellesøy M, Fagerholt OHE, Gullaksen SE, Srivastava A, Birkeland E, Kleftogiannis D, Ayuda-Durán P, Piechaczyk L, Tadele DS, Skavland J, Baliakas P, Hovland R, Andresen V, Seternes OM, Tvedt THA, Aghaeepour N, Gavasso S, Porkka K, Jonassen I, Fløisand Y, Enserink J, Blaser N, Gjertsen BT (2023)
    Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia
    Nat Commun, 14 (1), 1767
    DOI 10.1038/s41467-023-37488-8, PubMed 36997540
  37. Totland MZ, Omori Y, Sørensen V, Kryeziu K, Aasen T, Brech A, Leithe E (2023)
    Endocytic trafficking of connexins in cancer pathogenesis
    Biochim Biophys Acta Mol Basis Dis, 1869 (7), 166812
    DOI 10.1016/j.bbadis.2023.166812, PubMed 37454772
  38. van den Berg CM, Volkov VA, Schnorrenberg S, Huang Z, Stecker KE, Grigoriev I, Gilani S, Frikstad KM, Patzke S, Zimmermann T, Dogterom M, Akhmanova A (2023)
    CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side
    J Cell Biol, 222 (4)
    DOI 10.1083/jcb.202208062, PubMed 36752787
  39. van Royen ME, Soekmadji C, Grange C, Webber JP, Tertel T, Droste M, Buescher A, Giebel B, Jenster GW, Llorente A, Blijdorp CJ, Burger D, Erdbrügger U, Martens-Uzunova ES (2023)
    The quick reference card "Storage of urinary EVs" - A practical guideline tool for research and clinical laboratories
    J Extracell Vesicles, 12 (3), e12286
    DOI 10.1002/jev2.12286, PubMed 36916183
  40. Wu C, Gunnarsson EB, Myklebust EM, Köhn-Luque A, Tadele DS, Enserink JM, Frigessi A, Foo J, Leder K (2023)
    Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data
    ArXiv
    PubMed 37396610
  41. Yao Y, Sun H, Wurihan, Gegeheng, Gezi, Skarstad K, Fan L, Morigen (2023)
    A DnaA‐dependent riboswitch for transcription attenuation of the his operon
    mLife, 2 (2), 126-140
    DOI 10.1002/mlf2.12075, PublikaID 479
  42. Yao Y, Sun H, Wurihan, Gegeheng, Gezi, Skarstad K, Fan L, Morigen (2023)
    A DnaA-dependent riboswitch for transcription attenuation of the his operon
    mLife, 2 (2), 126-140
    DOI 10.1002/mlf2.12075, PubMed 38817620
  43. Zhen Y, Stenmark H (2023)
    Autophagosome Biogenesis
    Cells, 12 (4)
    DOI 10.3390/cells12040668, PubMed 36831335
  44. Zhen Y, Stenmark H (2023)
    A phosphoinositide kinase triggers migrasome formation
    Cell Res, 33 (8), 577-578
    DOI 10.1038/s41422-023-00822-2, PubMed 37165066

Publications 2022

  1. Arora A, Kivelä AM, Wang L, Minkeviciene R, Taskinen JH, Zhang B, Koponen A, Sun J, Shirane M, Zhou Y, Hotulainen P, Raiborg C, Olkkonen VM (2022)
    Protrudin regulates FAK activation, endothelial cell migration and angiogenesis
    Cell Mol Life Sci, 79 (4), 220
    DOI 10.1007/s00018-022-04251-z, PubMed 35368213
  2. Blijdorp CJ, Burger D, Llorente A, Martens-Uzunova ES, Erdbrügger U (2022)
    Extracellular Vesicles as Novel Players in Kidney Disease
    J Am Soc Nephrol, 33 (3), 467-471
    DOI 10.1681/ASN.2021091232, PubMed 35131841
  3. Bousquet PA, Manna D, Sandvik JA, Arntzen MØ, Moreno E, Sandvig K, Krengel U (2022)
    SILAC-based quantitative proteomics and microscopy analysis of cancer cells treated with the N-glycolyl GM3-specific anti-tumor antibody 14F7
    Front Immunol, 13, 994790
    DOI 10.3389/fimmu.2022.994790, PubMed 36439103
  4. Bril'kov MS, Dobrovolska O, Ødegård-Fougner Ø, Turcu DC, Strømland Ø, Underhaug J, Aasland R, Halskau Ø (2022)
    Binding Specificity of ASHH2 CW Domain Toward H3K4me1 Ligand Is Coupled to Its Structural Stability Through Its α1-Helix
    Front Mol Biosci, 9, 763750
    DOI 10.3389/fmolb.2022.763750, PubMed 35495628
  5. Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J et al. (2022)
    Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
    Ann N Y Acad Sci, 1510 (1), 79-99
    DOI 10.1111/nyas.14745, PubMed 35000205
  6. Charsou C, Ng MYW, Simonsen A (2022)
    Regulation of autophagosome biogenesis and mitochondrial bioenergetics by the cholesterol transport protein GRAMD1C
    Autophagy, 19 (7), 2159-2161
    DOI 10.1080/15548627.2022.2155020, PubMed 36469687
  7. Doncheva AI, Romero S, Ramirez-Garrastacho M, Lee S, Kolnes KJ, Tangen DS, Olsen T, Drevon CA, Llorente A, Dalen KT, Hjorth M (2022)
    Extracellular vesicles and microRNAs are altered in response to exercise, insulin sensitivity and overweight
    Acta Physiol (Oxf), 236 (4), e13862
    DOI 10.1111/apha.13862, PubMed 36377504
  8. Du H, Yang F, Yao C, Lv W, Peng H, Stanciu SG, Stenmark HA, Song YM, Jiang B, Wu A (2022)
    "Double-punch" strategy against triple-negative breast cancer via a synergistic therapy of magneto-mechanical force enhancing NIR-II hypothermal ablation
    Biomaterials, 291, 121868
    DOI 10.1016/j.biomaterials.2022.121868, PubMed 36332286
  9. Du H, Yang F, Yao C, Zhong Z, Jiang P, Stanciu SG, Peng H, Hu J, Jiang B, Li Z, Lv W, Zheng F, Stenmark HA, Wu A (2022)
    Multifunctional Modulation of High-Performance Znx Fe3-x O4 Nanoparticles by Precisely Tuning the Zinc Doping Content
    Small, 18 (42), e2201669
    DOI 10.1002/smll.202201669, PubMed 36101918
  10. Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML (2022)
    Measuring Autophagic Cargo Flux with Keima-Based Probes
    Methods Mol Biol, 2445, 99-115
    DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988
  11. Enserink JM (2022)
    The SUMO stress response in transcriptional regulation: Causal relationships or secondary bystander effects?
    Bioessays, 44 (7), e2200065
    DOI 10.1002/bies.202200065, PubMed 35655365
  12. Enserink JM, Chymkowitch P (2022)
    Cell Cycle-Dependent Transcription: The Cyclin Dependent Kinase Cdk1 Is a Direct Regulator of Basal Transcription Machineries
    Int J Mol Sci, 23 (3)
    DOI 10.3390/ijms23031293, PubMed 35163213
  13. Espeland K, Kleinauskas A, Juzenas P, Brech A, Darvekar S, Vasovic V, Warloe T, Christensen E, Jahnsen J, Peng Q (2022)
    Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells
    Biomedicines, 10 (2)
    DOI 10.3390/biomedicines10020232, PubMed 35203441
  14. Fiorito E, Szybowska P, Haugsten EM, Kostas M, Øy GF, Wiedlocha A, Singh S, Nakken S, Mælandsmo GM, Fletcher JA, Meza-Zepeda LA, Wesche J (2022)
    Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
    Br J Cancer, 127 (11), 1939-1953
    DOI 10.1038/s41416-022-01973-6, PubMed 36097178
  15. Forcados C, Joaquina S, Casey NP, Caulier B, Wälchli S (2022)
    How CAR T Cells Breathe
    Cells, 11 (9)
    DOI 10.3390/cells11091454, PubMed 35563759
  16. Frikstad KM, Schink KO, Gilani S, Pedersen LB, Patzke S (2022)
    3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines
    Bio Protoc, 12 (6), e4360
    DOI 10.21769/BioProtoc.4360, PubMed 35434191
  17. Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2022)
    Corrigendum to "Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft", [Journal of Control Release, 293 (2019) 183-192]
    J Control Release, 349, 1
    DOI 10.1016/j.jconrel.2022.06.040, PubMed 35792388
  18. Ganley IG, Simonsen A (2022)
    Diversity of mitophagy pathways at a glance
    J Cell Sci, 135 (23)
    DOI 10.1242/jcs.259748, PubMed 36504076
  19. Garcia-Garcia J, Berge AKM, Overå KS, Larsen KB, Bhujabal Z, Brech A, Abudu YP, Lamark T, Johansen T, Sjøttem E (2022)
    TRIM27 is an autophagy substrate facilitating mitochondria clustering and mitophagy via phosphorylated TBK1
    FEBS J, 290 (4), 1096-1116
    DOI 10.1111/febs.16628, PubMed 36111389
  20. Holland P, Quintana EM, Khezri R, Schoborg TA, Rusten TE (2022)
    Computed tomography with segmentation and quantification of individual organs in a D. melanogaster tumor model
    Sci Rep, 12 (1), 2056
    DOI 10.1038/s41598-022-05991-5, PubMed 35136137
  21. Khezri R, Rusten TE (2022)
    Autophagy power expands: fuse those cells!
    EMBO J, 41 (12), e111424
    DOI 10.15252/embj.2022111424, PubMed 35561082
  22. Lampart A, Sluzalska KD, Czyrek A, Szerszen A, Otlewski J, Wiedlocha A, Zakrzewska M (2022)
    Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells
    Cells, 11 (3)
    DOI 10.3390/cells11030522, PubMed 35159330
  23. Lobert VH, Skardal ML, Malerød L, Simensen JE, Algra HA, Andersen AN, Fleischer T, Enserink HA, Liestøl K, Heath JK, Rusten TE, Stenmark HA (2022)
    PHLPP1 regulates CFTR activity and lumen expansion through AMPK
    Development, 149 (20)
    DOI 10.1242/dev.200955, PubMed 35997536
  24. Mateus D, Wiedlocha A (2022)
    FGF-FGFR signaling promotes the development of invasive cervical cancer
    FEBS J, 289 (12), 3419-3421
    DOI 10.1111/febs.16384, PubMed 35146913
  25. Mehto S, Jena KK, Yadav R, Priyadarsini S, Samal P, Krishna S, Dhar K, Jain A, Chauhan NR, Murmu KC, Bal R, Sahu R, Jaiswal P, Sahoo BS, Patnaik S, Kufer TA, Rusten TE, Chauhan S, Prasad P, Chauhan S (2022)
    Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection
    EMBO J, 41 (23), e111289
    DOI 10.15252/embj.2022111289, PubMed 36221902
  26. Mezzasoma L, Bellezza I, Orvietani P, Manni G, Gargaro M, Sagini K, Llorente A, Scarpelli P, Pascucci L, Cellini B, Talesa VN, Fallarino F, Romani R (2022)
    Amniotic fluid stem cell-derived extracellular vesicles are independent metabolic units capable of modulating inflammasome activation in THP-1 cells
    FASEB J, 36 (4), e22218
    DOI 10.1096/fj.202101657R, PubMed 35218567
  27. Migliano SM, Stenmark H (2022)
    ESCRTed resistance to T cell attack
    Trends Immunol, 43 (8), 598-600
    DOI 10.1016/j.it.2022.06.007, PubMed 35810056
  28. Migliano SM, Wenzel EM, Stenmark H (2022)
    Biophysical and molecular mechanisms of ESCRT functions, and their implications for disease
    Curr Opin Cell Biol, 75, 102062
    DOI 10.1016/j.ceb.2022.01.007, PubMed 35248976
  29. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Simonsen A (2022)
    GAK and PRKCD kinases regulate basal mitophagy
    Autophagy, 18 (2), 467-469
    DOI 10.1080/15548627.2021.2015154, PubMed 35001811
  30. Ng MYW, Charsou C, Lapao A, Singh S, Trachsel-Moncho L, Schultz SW, Nakken S, Munson MJ, Simonsen A (2022)
    The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
    Nat Commun, 13 (1), 6283
    DOI 10.1038/s41467-022-33933-2, PubMed 36270994
  31. Nissen-Meyer J, Skotland T, Boye E (2022)
    Are doping tests in sports trustworthy?: Athletes suffer from insufficiently defined criteria for doping tests: Athletes suffer from insufficiently defined criteria for doping tests
    EMBO Rep, 23 (3), e54431
    DOI 10.15252/embr.202154431, PubMed 35156749
  32. Radulovic M, Wenzel EM, Gilani S, Holland LK, Lystad AH, Phuyal S, Olkkonen VM, Brech A, Jäättelä M, Maeda K, Raiborg C, Stenmark H (2022)
    Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
    EMBO J, 41 (24), e112677
    DOI 10.15252/embj.2022112677, PubMed 36408828
  33. Rahman MA, Engelsen AST, Sarowar S, Bindesbøll C, Birkeland E, Goplen D, Lotsberg ML, Knappskog S, Simonsen A, Chekenya M (2022)
    Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway
    Front Cell Dev Biol, 10, 1022191
    DOI 10.3389/fcell.2022.1022191, PubMed 36619857
  34. Ramos-Alonso L, Garcia I, Enserink JM, Chymkowitch P (2022)
    Analysis of the pheromone signaling pathway by RT-qPCR in the budding yeast Saccharomyces cerevisiae
    STAR Protoc, 3 (1), 101210
    DOI 10.1016/j.xpro.2022.101210, PubMed 35265859
  35. Romaine A, Melleby AO, Alam J, Lobert VH, Lu N, Lockwood FE, Hasic A, Lunde IG, Sjaastad I, Stenmark H, Herum KM, Gullberg D, Christensen G (2022)
    Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart
    Am J Physiol Heart Circ Physiol, 322 (6), H1057-H1071
    DOI 10.1152/ajpheart.00635.2021, PubMed 35522553
  36. Sandvig K, Kavaliauskiene S, Myrann AG, Iversen TG, Skotland T (2022)
    Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC
    Toxins (Basel), 14 (5)
    DOI 10.3390/toxins14050360, PubMed 35622606
  37. Sikkeland J, Ng MYW, Nenseth HZ, Unal B, Qu S, Jin Y, Simonsen A, Saatcioglu F (2022)
    STAMP2 suppresses autophagy in prostate cancer cells by modulating the integrated stress response pathway
    Am J Cancer Res, 12 (1), 327-336
    PubMed 35141021
  38. Simonsen A, Wollert T (2022)
    Don't forget to be picky - selective autophagy of protein aggregates in neurodegenerative diseases
    Curr Opin Cell Biol, 75, 102064
    DOI 10.1016/j.ceb.2022.01.009, PubMed 35240373
  39. Skotland T, Iversen TG, Llorente A, Sandvig K (2022)
    Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges
    Adv Drug Deliv Rev, 186, 114326
    DOI 10.1016/j.addr.2022.114326, PubMed 35588953
  40. Skotland T, Sandvig K (2022)
    Need for more focus on lipid species in studies of biological and model membranes
    Prog Lipid Res, 86, 101160
    DOI 10.1016/j.plipres.2022.101160, PubMed 35288150
  41. Stanciu SG, Hristu R, Stanciu GA, Tranca DE, Eftimie L, Dumitru A, Costache M, Stenmark HA, Manders H, Cherian A, Tark-Dame M, Manders EMM (2022)
    Super-resolution re-scan second harmonic generation microscopy
    Proc Natl Acad Sci U S A, 119 (47), e2214662119
    DOI 10.1073/pnas.2214662119, PubMed 36375085
  42. Stanciu SG, Tranca DE, Zampini G, Hristu R, Stanciu GA, Chen X, Liu M, Stenmark HA, Latterini L (2022)
    Scattering-type Scanning Near-Field Optical Microscopy of Polymer-Coated Gold Nanoparticles
    ACS Omega, 7 (13), 11353-11362
    DOI 10.1021/acsomega.2c00410, PubMed 35415325
  43. Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
    ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
    J Cell Sci, 135 (4)
    DOI 10.1242/jcs.259138, PubMed 35099014
  44. Wenzel EM, Elfmark LA, Stenmark H, Raiborg C (2022)
    ER as master regulator of membrane trafficking and organelle function
    J Cell Biol, 221 (10)
    DOI 10.1083/jcb.202205135, PubMed 36108241
  45. Wenzel EM, Raiborg C (2022)
    ER-endosome contacts master the ins and outs of secretory endosomes
    J Cell Biol, 221 (12)
    DOI 10.1083/jcb.202210033, PubMed 36355088
  46. Xu J, Yang KC, Go NE, Colborne S, Ho CJ, Hosseini-Beheshti E, Lystad AH, Simonsen A, Guns ET, Morin GB, Gorski SM (2022)
    Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
    Autophagy, 18 (11), 2547-2560
    DOI 10.1080/15548627.2022.2039535, PubMed 35220892
  47. Zendrini A, Guerra G, Sagini K, Vagner T, Di Vizio D, Bergese P (2022)
    On the surface-to-bulk partition of proteins in extracellular vesicles
    Colloids Surf B Biointerfaces, 218, 112728
    DOI 10.1016/j.colsurfb.2022.112728, PubMed 35969923
  48. Zhao X, Hendriks IA, Le Gras S, Ye T, Ramos-Alonso L, Nguéa P A, Lien GF, Ghasemi F, Klungland A, Jost B, Enserink JM, Nielsen ML, Chymkowitch P (2022)
    Waves of sumoylation support transcription dynamics during adipocyte differentiation
    Nucleic Acids Res, 50 (3), 1351-1369
    DOI 10.1093/nar/gkac027, PubMed 35100417

Publications 2021

  1. Agudo-Canalejo J, Schultz SW, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, May AI, Mizushima N, Knorr RL (2021)
    Wetting regulates autophagy of phase-separated compartments and the cytosol
    Nature, 591 (7848), 142-146
    DOI 10.1038/s41586-020-2992-3, PubMed 33473217
  2. Aman Y, Schmauck-Medina T, Hansen M, Morimoto RI, Simon AK, Bjedov I, Palikaras K, Simonsen A, Johansen T, Tavernarakis N, Rubinsztein DC, Partridge L, Kroemer G, Labbadia J, Fang EF (2021)
    Autophagy in healthy aging and disease
    Nat Aging, 1 (8), 634-650
    DOI 10.1038/s43587-021-00098-4, PubMed 34901876
  3. Anda S, Boye E, Schink KO, Grallert B (2021)
    Cosegregation of asymmetric features during cell division
    Open Biol, 11 (8), 210116
    DOI 10.1098/rsob.210116, PubMed 34343465
  4. Bjørnetrø T, Steffensen LA, Vestad B, Brusletto BS, Olstad OK, Trøseid AM, Aass HCD, Haug KBF, Llorente A, Bøe SO, Lång A, Samiappan R, Redalen KR, Øvstebø R, Ree AH (2021)
    Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
    FEBS Open Bio, 11 (3), 724-740
    DOI 10.1002/2211-5463.13098, PubMed 33512765
  5. Buratta S, Shimanaka Y, Costanzi E, Ni S, Urbanelli L, Kono N, Morena F, Sagini K, Giovagnoli S, Romani R, Gargaro M, Arai H, Emiliani C (2021)
    Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
    Sci Rep, 11 (1), 4613
    DOI 10.1038/s41598-021-84268-9, PubMed 33633289
  6. Caulier B, Enserink JM, Wälchli S (2021)
    Pharmacologic Control of CAR T Cells
    Int J Mol Sci, 22 (9)
    DOI 10.3390/ijms22094320, PubMed 33919245
  7. Dillard C, Reis JGT, Rusten TE (2021)
    RasV12; scrib-/- Tumors: A Cooperative Oncogenesis Model Fueled by Tumor/Host Interactions
    Int J Mol Sci, 22 (16)
    DOI 10.3390/ijms22168873, PubMed 34445578
  8. Erdbrügger U, Blijdorp CJ, Bijnsdorp IV, Borràs FE, Burger D, Bussolati B, Byrd JB, Clayton A, Dear JW, Falcón-Pérez JM, Grange C, Hill AF, Holthöfer H, Hoorn EJ, Jenster G, Jimenez CR, Junker K, Klein J, Knepper MA, Koritzinsky EH, Luther JM, Lenassi M, Leivo J, Mertens I, Musante L et al. (2021)
    Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
    J Extracell Vesicles, 10 (7), e12093
    DOI 10.1002/jev2.12093, PubMed 34035881
  9. Fernandes P, Miotto B, Saint-Ruf C, Said M, Barra V, Nähse V, Ravera S, Cappelli E, Naim V (2021)
    FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
    Commun Biol, 4 (1), 127
    DOI 10.1038/s42003-021-01647-8, PubMed 33514811
  10. Fløisand Y, Schroeder MA, Chevallier P, Selleslag D, Devine S, Renteria AS, Mohty M, Yakoub-Agha I, Chen C, Parfionovas A, Quadri S, Jansson J, Akbari M, Chen YB (2021)
    A phase 2a randomized clinical trial of intravenous vedolizumab for the treatment of steroid-refractory intestinal acute graft-versus-host disease
    Bone Marrow Transplant, 56 (10), 2477-2488
    DOI 10.1038/s41409-021-01356-0, PubMed 34108672
  11. Formica M, Storaci AM, Bertolini I, Carminati F, Knævelsrud H, Vaira V, Vaccari T (2021)
    V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis
    Autophagy, 17 (12), 4442-4452
    DOI 10.1080/15548627.2021.1918915, PubMed 33978540
  12. Garcia I, Orellana-Muñoz S, Ramos-Alonso L, Andersen AN, Zimmermann C, Eriksson J, Bøe SO, Kaferle P, Papamichos-Chronakis M, Chymkowitch P, Enserink JM (2021)
    Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
    Cell Rep, 37 (13), 110186
    DOI 10.1016/j.celrep.2021.110186, PubMed 34965431
  13. Giovannucci TA, Salomons FA, Stoy H, Herzog LK, Xu S, Qian W, Merino LG, Gierisch ME, Haraldsson M, Lystad AH, Uvell H, Simonsen A, Gustavsson AL, Vallin M, Dantuma NP (2021)
    Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
    Autophagy, 18 (7), 1486-1502
    DOI 10.1080/15548627.2021.1988359, PubMed 34740308
  14. Grad I, Hanes R, Ayuda-Durán P, Kuijjer ML, Enserink JM, Meza-Zepeda LA, Myklebost O (2021)
    Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
    PLoS One, 16 (3), e0248140
    DOI 10.1371/journal.pone.0248140, PubMed 33690666
  15. Guerriero I, Ramberg H, Sagini K, Ramirez-Garrastacho M, Taskén KA, Llorente A (2021)
    Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells
    PLoS One, 16 (6), e0253828
    DOI 10.1371/journal.pone.0253828, PubMed 34191854
  16. Holland P, Hagopian WM, Jahren AH, Rusten TE (2021)
    Natural abundance isotope ratios to differentiate sources of carbon used during tumor growth in vivo
    BMC Biol, 19 (1), 85
    DOI 10.1186/s12915-021-01012-5, PubMed 33966633
  17. Iglesias R, Ferreras JM, Llorente A, Citores L (2021)
    Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication
    Toxins (Basel), 13 (2)
    DOI 10.3390/toxins13020102, PubMed 33573355
  18. Khezri R, Holland P, Schoborg TA, Abramovich I, Takáts S, Dillard C, Jain A, O'Farrell F, Schultz SW, Hagopian WM, Quintana EM, Ng R, Katheder NS, Rahman MM, Teles Reis JG, Brech A, Jasper H, Rusan NM, Jahren AH, Gottlieb E, Rusten TE (2021)
    Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
    EMBO J, 40 (18), e107336
    DOI 10.15252/embj.2020107336, PubMed 34309071
  19. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
    Autophagy, 17 (1), 1-382
    DOI 10.1080/15548627.2020.1797280, PubMed 33634751
  20. Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen EL, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T et al. (2021)
    Autophagy in major human diseases
    EMBO J, 40 (19), e108863
    DOI 10.15252/embj.2021108863, PubMed 34459017
  21. Kosanović M, Llorente A, Glamočlija S, Valdivielso JM, Bozic M (2021)
    Extracellular Vesicles and Renal Fibrosis: An Odyssey toward a New Therapeutic Approach
    Int J Mol Sci, 22 (8)
    DOI 10.3390/ijms22083887, PubMed 33918699
  22. Krzyscik MA, Zakrzewska M, Sørensen V, Øy GF, Brunheim S, Haugsten EM, Mælandsmo GM, Wiedlocha A, Otlewski J (2021)
    Fibroblast Growth Factor 2 Conjugated with Monomethyl Auristatin E Inhibits Tumor Growth in a Mouse Model
    Biomacromolecules, 22 (10), 4169-4180
    DOI 10.1021/acs.biomac.1c00662, PubMed 34542998
  23. Martens-Uzunova ES, Blijdorp CJ, Burger D, Erdbrügger U, Llorente A (2021)
    Urinary Extracellular Vesicles in Urology: Current Successes and Challenges Ahead
    Eur Urol, 81 (1), 127-128
    DOI 10.1016/j.eururo.2021.09.025, PubMed 34625312
  24. Melvold K, Giliberto M, Karlsen L, Ayuda-Durán P, Hanes R, Holien T, Enserink J, Brown JR, Tjønnfjord GE, Taskén K, Skånland SS (2021)
    Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
    Mol Oncol, 16 (5), 1153-1170
    DOI 10.1002/1878-0261.13153, PubMed 34861096
  25. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A (2021)
    GAK and PRKCD are positive regulators of PRKN-independent mitophagy
    Nat Commun, 12 (1), 6101
    DOI 10.1038/s41467-021-26331-7, PubMed 34671015
  26. Mygland L, Brinch SA, Strand MF, Olsen PA, Aizenshtadt A, Lund K, Solberg NT, Lycke M, Thorvaldsen TE, Espada S, Misaghian D, Page CM, Agafonov O, Nygård S, Chi NW, Lin E, Tan J, Yu Y, Costa M, Krauss S, Waaler J (2021)
    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
    iScience, 24 (7), 102807
    DOI 10.1016/j.isci.2021.102807, PubMed 34337362
  27. Nowosielska EM, Cheda A, Pociegiel M, Cheda L, Szymański P, Wiedlocha A (2021)
    Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice
    Int J Mol Sci, 22 (12)
    DOI 10.3390/ijms22126309, PubMed 34208396
  28. Pandya AD, Iversen TG, Moestue S, Grinde MT, Mørch Ý, Snipstad S, Åslund AKO, Øy GF, Kildal W, Engebråten O, Sandvig K, Skotland T, Mælandsmo GM (2021)
    Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
    Nanomaterials (Basel), 11 (5)
    DOI 10.3390/nano11051140, PubMed 33924869
  29. Ramirez-Garrastacho M, Bajo-Santos C, Line A, Martens-Uzunova ES, de la Fuente JM, Moros M, Soekmadji C, Tasken KA, Llorente A (2021)
    Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research
    Br J Cancer, 126 (3), 331-350
    DOI 10.1038/s41416-021-01610-8, PubMed 34811504
  30. Ramirez-Garrastacho M, Berge V, Linē A, Llorente A (2021)
    Potential of miRNAs in urinary extracellular vesicles for management of active surveillance in prostate cancer patients
    Br J Cancer, 126 (3), 492-501
    DOI 10.1038/s41416-021-01598-1, PubMed 34811506
  31. Ravussin A, Brech A, Tooze SA, Stenmark H (2021)
    The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy
    J Cell Sci, 134 (3)
    DOI 10.1242/jcs.250670, PubMed 33468622
  32. Rudolph MJ, Poon AY, Kavaliauskiene S, Myrann AG, Reynolds-Peterson C, Davis SA, Sandvig K, Vance DJ, Mantis NJ (2021)
    Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface
    J Mol Biol, 433 (15), 167086
    DOI 10.1016/j.jmb.2021.167086, PubMed 34089718
  33. Rønneberg L, Cremaschi A, Hanes R, Enserink JM, Zucknick M (2021)
    bayesynergy: flexible Bayesian modelling of synergistic interaction effects in in vitro drug combination experiments
    Brief Bioinform, 22 (6)
    DOI 10.1093/bib/bbab251, PubMed 34308471
  34. Sandvig K, Kavaliauskiene S, Skotland T (2021)
    The Protein Toxins Ricin and Shiga Toxin as Tools to Explore Cellular Mechanisms of Internalization and Intracellular Transport
    Toxins (Basel), 13 (6)
    DOI 10.3390/toxins13060377, PubMed 34070659
  35. Schink KO, Tan KW, Spangenberg H, Martorana D, Sneeggen M, Stévenin V, Enninga J, Campsteijn C, Raiborg C, Stenmark H (2021)
    The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes
    Nat Commun, 12 (1), 6577
    DOI 10.1038/s41467-021-26775-x, PubMed 34772942
  36. Schultz SW, Agudo-Canalejo J, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, Mizushima N, Knorr RL, May AI (2021)
    Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
    Autophagy, 17 (4), 1046-1048
    DOI 10.1080/15548627.2021.1887548, PubMed 33629888
  37. Sharma K, Asp NT, Harrison S, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A (2021)
    Autophagy modulates cell fate decisions during lineage commitment
    Autophagy, 18 (8), 1915-1931
    DOI 10.1080/15548627.2021.2008691, PubMed 34923909
  38. Siokis A, Robert PA, Demetriou P, Kvalvaag A, Valvo S, Mayya V, Dustin ML, Meyer-Hermann M (2021)
    Characterization of mechanisms positioning costimulatory complexes in immune synapses
    iScience, 24 (10), 103100
    DOI 10.1016/j.isci.2021.103100, PubMed 34622155
  39. Skotland T, Iversen TG, Sandvig K (2021)
    Cellular uptake of nanoparticles: Involvement of caveolae?
    Precis Nanomed, 4 (2), 782-786
    DOI 10.33218/001c.22201, PublikaID 365
  40. Skotland T, Sandvig K (2021)
    Transport of nanoparticles across the endothelial cell layer
    Nano Today, 36, 101029
    DOI 10.1016/j.nantod.2020.101029
  41. Szybowska P, Kostas M, Wesche J, Haugsten EM, Wiedlocha A (2021)
    Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
    Cells, 10 (6)
    DOI 10.3390/cells10061342, PubMed 34071546
  42. Sønstevold T, Engedal N, Torgersen ML (2021)
    Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy
    Cells, 10 (12)
    DOI 10.3390/cells10123432, PubMed 34943939
  43. Tan KW (2021)
    First person - Kia Wee Tan
    J. Cell Sci., 134 (14), jcs259055
    DOI 10.1242/jcs.259055
  44. Tan KW, Nähse V, Campsteijn C, Brech A, Schink KO, Stenmark H (2021)
    JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes
    J Cell Sci, 134 (14)
    DOI 10.1242/jcs.258495, PubMed 34109410
  45. Valko A, Perez-Pandolfo S, Sorianello E, Brech A, Wappner P, Melani M (2021)
    Adaptation to hypoxia in Drosophila melanogaster requires autophagy
    Autophagy, 18 (4), 909-920
    DOI 10.1080/15548627.2021.1991191, PubMed 34793268
  46. Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
    Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
    Int J Pharm, 597, 120217
    DOI 10.1016/j.ijpharm.2021.120217, PubMed 33486035
  47. Weisheit S, Wegner CS, Ailte I, Radulovic M, Weyergang A, Selbo PK, Brech A (2021)
    Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
    Biochem Pharmacol, 194, 114837
    DOI 10.1016/j.bcp.2021.114837, PubMed 34780750
  48. Wiedlocha A, Haugsten EM, Zakrzewska M (2021)
    Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation
    Cells, 10 (9)
    DOI 10.3390/cells10092231, PubMed 34571880
  49. Wirth M, Mouilleron S, Zhang W, Sjøttem E, Abudu YP, Jain A, Olsvik HL, Bruun JA, Razi M, Jefferies HBJ, Lee R, Joshi D, O'Reilly N, Johansen T, Tooze SA (2021)
    Corrigendum to Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
    J Mol Biol, 433 (15), 167049
    DOI 10.1016/j.jmb.2021.167049, PubMed 34052024
  50. Wirth M, Mouilleron S, Zhang W, Sjøttem E, Princely Abudu Y, Jain A, Lauritz Olsvik H, Bruun JA, Razi M, Jefferies HBJ, Lee R, Joshi D, O'Reilly N, Johansen T, Tooze SA (2021)
    Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
    J Mol Biol, 433 (13), 166987
    DOI 10.1016/j.jmb.2021.166987, PubMed 33845085
  51. Zdżalik-Bielecka D, Poświata A, Kozik K, Jastrzębski K, Schink KO, Brewińska-Olchowik M, Piwocka K, Stenmark H, Miączyńska M (2021)
    The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion
    Proc Natl Acad Sci U S A, 118 (28)
    DOI 10.1073/pnas.2024596118, PubMed 34244439
  52. Zhen Y, Radulovic M, Vietri M, Stenmark H (2021)
    Sealing holes in cellular membranes
    EMBO J, 40 (7), e106922
    DOI 10.15252/embj.2020106922, PubMed 33644904
  53. Øverbye A, Torgersen ML, Sønstevold T, Iversen TG, Mørch Ý, Skotland T, Sandvig K (2021)
    Cabazitaxel-loaded poly(alkyl cyanoacrylate) nanoparticles: toxicity and changes in the proteome of breast, colon and prostate cancer cells
    Nanotoxicology, 15 (7), 865-884
    DOI 10.1080/17435390.2021.1924888, PubMed 34047629

Publications 2020

  1. Buratta S, Tancini B, Sagini K, Delo F, Chiaradia E, Urbanelli L, Emiliani C (2020)
    Lysosomal Exocytosis, Exosome Release and Secretory Autophagy: The Autophagic- and Endo-Lysosomal Systems Go Extracellular
    Int J Mol Sci, 21 (7)
    DOI 10.3390/ijms21072576, PubMed 32276321
  2. Caglayan S, Hashim A, Cieslar-Pobuda A, Jensen V, Behringer S, Talug B, Chu DT, Pecquet C, Rogne M, Brech A, Brorson SH, Nagelhus EA, Hannibal L, Boschi A, Taskén K, Staerk J (2020)
    Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
    iScience, 23 (6), 101154
    DOI 10.1016/j.isci.2020.101154, PubMed 32450518
  3. Dillard P, Lie M, Baken E, Lobert VH, Benard E, Köksal H, Inderberg EM, Wälchli S (2020)
    Colorectal cysts as a validating tool for CAR therapy
    BMC Biotechnol, 20 (1), 30
    DOI 10.1186/s12896-020-00623-0, PubMed 32487146
  4. Grønvold B, Ali MM, Remberger M, Mattsson J, Egeland T, Lundin KU, Myhre AE, Abrahamsen IW, Heldal D, Dybedal I, Tjønnfjord GE, Fløisand Y, Gedde-Dahl T (2020)
    HLA-DPB1 mismatch reduce relapse and improve survival in T-cell replete unrelated donor allogeneic stem cell transplantation
    Bone Marrow Transplant, 55 (8), 1658-1661
    DOI 10.1038/s41409-020-0827-3, PubMed 32054997
  5. Jacomin AC, Gohel R, Hussain Z, Varga A, Maruzs T, Eddison M, Sica M, Jain A, Moffat KG, Johansen T, Jenny A, Juhasz G, Nezis IP (2020)
    Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila
    Life Sci Alliance, 4 (2)
    DOI 10.26508/lsa.202000965, PubMed 33318080
  6. Jacomin AC, Petridi S, Di Monaco M, Bhujabal Z, Jain A, Mulakkal NC, Palara A, Powell EL, Chung B, Zampronio C, Jones A, Cameron A, Johansen T, Nezis IP (2020)
    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
    Cell Rep, 31 (8), 107695
    DOI 10.1016/j.celrep.2020.107695, PubMed 32460019
  7. Jakobi AJ, Huber ST, Mortensen SA, Schultz SW, Palara A, Kuhm T, Shrestha BK, Lamark T, Hagen WJH, Wilmanns M, Johansen T, Brech A, Sachse C (2020)
    Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake
    Nat Commun, 11 (1), 440
    DOI 10.1038/s41467-020-14343-8, PubMed 31974402
  8. Jena KK, Mehto S, Nath P, Chauhan NR, Sahu R, Dhar K, Das SK, Kolapalli SP, Murmu KC, Jain A, Krishna S, Sahoo BS, Chattopadhyay S, Rusten TE, Prasad P, Chauhan S, Chauhan S (2020)
    Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response
    EMBO Rep, 21 (9), e50051
    DOI 10.15252/embr.202050051, PubMed 32715615
  9. Jendryczko K, Chudzian J, Skinder N, Opaliński Ł, Rzeszótko J, Wiedlocha A, Otlewski J, Szlachcic A (2020)
    FGF2-Derived PeptibodyF2-MMAE Conjugate for Targeted Delivery of Cytotoxic Drugs into Cancer Cells Overexpressing FGFR1
    Cancers (Basel), 12 (10)
    DOI 10.3390/cancers12102992, PubMed 33076489
  10. Kolapalli SP, Sahu R, Chauhan NR, Jena KK, Mehto S, Das SK, Jain A, Rout M, Dash R, Swain RK, Lee DY, Rusten TE, Chauhan S, Chauhan S (2020)
    RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression
    Cancer Res, 81 (2), 315-331
    DOI 10.1158/0008-5472.CAN-20-1871, PubMed 33067265
  11. Kumar S, Jain A, Choi SW, da Silva GPD, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
    Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
    Nat Cell Biol, 22 (8), 973-985
    DOI 10.1038/s41556-020-0549-1, PubMed 32753672
  12. Kumar S, Jain A, Choi SW, da Silva GPD, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
    Author Correction: Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
    Nat Cell Biol, 22 (10), 1286
    DOI 10.1038/s41556-020-0574-0, PubMed 32788721
  13. Kumar S, Jain A, Choi SW, Peixoto Duarte da Silva G, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
    Mammalian Atg8-family proteins are upstream regulators of the lysosomalsystem by controlling MTOR and TFEB
    Autophagy, 16 (12), 2305-2306
    DOI 10.1080/15548627.2020.1837423, PubMed 33070669
  14. Laiouar S, Berns N, Brech A, Riechmann V (2020)
    RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism
    Curr Biol, 30 (7), 1177-1188.e5
    DOI 10.1016/j.cub.2020.01.048, PubMed 32059769
  15. Liese S, Wenzel EM, Kjos I, Rojas Molina R, Schultz SW, Brech A, Stenmark H, Raiborg C, Carlson A (2020)
    Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles
    Proc Natl Acad Sci U S A, 117 (46), 28614-28624
    DOI 10.1073/pnas.2014228117, PubMed 33139578
  16. Lingelem ABD, Kavaliauskiene S, Halsne R, Klokk TI, Surma MA, Klose C, Skotland T, Sandvig K (2020)
    Diacylglycerol kinase and phospholipase D inhibitors alter the cellular lipidome and endosomal sorting towards the Golgi apparatus
    Cell Mol Life Sci, 78 (3), 985-1009
    DOI 10.1007/s00018-020-03551-6, PubMed 32447426
  17. Martín-Gracia B, Martín-Barreiro A, Cuestas-Ayllón C, Grazú V, Line A, Llorente A, M de la Fuente J, Moros M (2020)
    Nanoparticle-based biosensors for detection of extracellular vesicles in liquid biopsies
    J Mater Chem B, 8 (31), 6710-6738
    DOI 10.1039/d0tb00861c, PubMed 32627783
  18. Mastrangelopoulou M, Grigalavicius M, Raabe TH, Skarpen E, Juzenas P, Peng Q, Berg K, Theodossiou TA (2020)
    Predictive biomarkers for 5-ALA-PDT can lead to personalized treatments and overcome tumor-specific resistances
    Cancer Rep (Hoboken), 5 (12), e1278
    DOI 10.1002/cnr2.1278, PubMed 32737955
  19. Munthe E, Raiborg C, Stenmark H, Wenzel EM (2020)
    Clathrin regulates Wnt/β-catenin signaling by affecting Golgi to plasma membrane transport of transmembrane proteins
    J Cell Sci, 133 (13)
    DOI 10.1242/jcs.244467, PubMed 32546530
  20. Nakstad ER, Stær-Jensen H, Wimmer H, Henriksen J, Alteheld LH, Reichenbach A, Drægni T, Šaltytė-Benth J, Wilson JA, Etholm L, Øijordsbakken M, Eritsland J, Seljeflot I, Jacobsen D, Andersen GØ, Lundqvist C, Sunde K (2020)
    Late awakening, prognostic factors and long-term outcome in out-of-hospital cardiac arrest - results of the prospective Norwegian Cardio-Respiratory Arrest Study (NORCAST)
    Resuscitation, 149, 170-179
    DOI 10.1016/j.resuscitation.2019.12.031, PubMed 31926258
  21. Ohnstad AE, Delgado JM, North BJ, Nasa I, Kettenbach AN, Schultz SW, Shoemaker CJ (2020)
    Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
    EMBO J, 39 (24), e104948
    DOI 10.15252/embj.2020104948, PubMed 33226137
  22. Omsland M, Andresen V, Gullaksen SE, Ayuda-Durán P, Popa M, Hovland R, Brendehaug A, Enserink J, McCormack E, Gjertsen BT (2020)
    Tyrosine kinase inhibitors and interferon-α increase tunneling nanotube (TNT) formation and cell adhesion in chronic myeloid leukemia (CML) cell lines
    FASEB J, 34 (3), 3773-3791
    DOI 10.1096/fj.201802061RR, PubMed 31945226
  23. Palušová V, Renzová T, Verlande A, Vaclová T, Medková M, Cetlová L, Sedláčková M, Hříbková H, Slaninová I, Krutá M, Rotrekl V, Uhlířová H, Křížová A, Chmelík R, Veselý P, Krafčíková M, Trantírek L, Schink KO, Uldrijan S (2020)
    Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds
    Cancers (Basel), 12 (6)
    DOI 10.3390/cancers12061516, PubMed 32531927
  24. Pandya AD, Øverbye A, Sahariah P, Gaware VS, Høgset H, Masson M, Høgset A, Mælandsmo GM, Skotland T, Sandvig K, Iversen TG (2020)
    Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
    Biomacromolecules, 21 (4), 1489-1498
    DOI 10.1021/acs.biomac.0c00061, PubMed 32092254
  25. Parfejevs V, Sagini K, Buss A, Sobolevska K, Llorente A, Riekstina U, Abols A (2020)
    Adult Stem Cell-Derived Extracellular Vesicles in Cancer Treatment: Opportunities and Challenges
    Cells, 9 (5)
    DOI 10.3390/cells9051171, PubMed 32397238
  26. Pedersen NM, Wenzel EM, Wang L, Antoine S, Chavrier P, Stenmark H, Raiborg C (2020)
    Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion
    J Cell Biol, 219 (8)
    DOI 10.1083/jcb.202003063, PubMed 32479595
  27. Radulovic M, Stenmark H (2020)
    LRRK2 to the rescue of damaged endomembranes
    EMBO J, 39 (18), e106162
    DOI 10.15252/embj.2020106162, PubMed 32803793
  28. Remberger M, Grønvold B, Ali M, Mattsson J, Egeland T, Lundin KU, Myhre A, Abrahamsen I, Heldal D, Dybedal I, Tjønnfjord GE, Gedde-Dahl T, Fløisand Y (2020)
    The CD34+ Cell Dose Matters in Hematopoietic Stem Cell Transplantation with Peripheral Blood Stem Cells from Sibling Donors
    Clin Hematol Int, 2 (2), 74-81
    DOI 10.2991/chi.d.200221.001, PubMed 34595446
  29. Skotland T, Kavaliauskiene S, Sandvig K (2020)
    The role of lipid species in membranes and cancer-related changes
    Cancer Metastasis Rev, 39 (2), 343-360
    DOI 10.1007/s10555-020-09872-z, PubMed 32314087
  30. Skotland T, Sagini K, Sandvig K, Llorente A (2020)
    An emerging focus on lipids in extracellular vesicles
    Adv Drug Deliv Rev, 159, 308-321
    DOI 10.1016/j.addr.2020.03.002, PubMed 32151658
  31. Solhaug A, Torgersen ML, Holme JA, Wiik-Nilsen J, Thiede B, Eriksen GS (2020)
    The Fusarium mycotoxin, 2-Amino-14,16-dimethyloctadecan-3-ol (AOD) induces vacuolization in HepG2 cells
    Toxicology, 433-434, 152405
    DOI 10.1016/j.tox.2020.152405, PubMed 32044396
  32. Szwed M, Torgersen ML, Kumari RV, Yadava SK, Pust S, Iversen TG, Skotland T, Giri J, Sandvig K (2020)
    Biological response and cytotoxicity induced by lipid nanocapsules
    J Nanobiotechnology, 18 (1), 5
    DOI 10.1186/s12951-019-0567-y, PubMed 31907052
  33. Sønstevold T, Engedal N, Mørch Ý, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2020)
    Structural Variants of poly(alkylcyanoacrylate) Nanoparticles Differentially Affect LC3 and Autophagic Cargo Degradation
    J Biomed Nanotechnol, 16 (4), 432-445
    DOI 10.1166/jbn.2020.2906, PubMed 32970976
  34. Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnová M, Piechaczyk L, Ayuda-Durán P, Singh SK, Gedde-Dahl T, Fløisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM (2020)
    A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
    J Biol Chem, 296, 100179
    DOI 10.1074/jbc.RA120.015285, PubMed 33303632
  35. Torgersen ML, Judge PJ, Bada Juarez JF, Pandya AD, Fusser M, Davies CW, Maciejewska MK, Yin DJ, Maelandsmo GM, Skotland T, Watts A, Sandvig K (2020)
    Physicochemical Characterization, Toxicity and In Vivo Biodistribution Studies of a Discoidal, Lipid-Based Drug Delivery Vehicle: Lipodisq Nanoparticles Containing Doxorubicin
    J Biomed Nanotechnol, 16 (4), 419-431
    DOI 10.1166/jbn.2020.2911, PubMed 32970975
  36. Tsjokajev A, Røberg-Larsen H, Wilson SR, Dyve Lingelem AB, Skotland T, Sandvig K, Lundanes E (2020)
    Mass spectrometry-based measurements of cyclic adenosine monophosphate in cells, simplified using reversed phase liquid chromatography with a polar characterized stationary phase
    J Chromatogr B Analyt Technol Biomed Life Sci, 1160, 122384
    DOI 10.1016/j.jchromb.2020.122384, PubMed 32971370
  37. Van Gool A, Corrales F, Čolović M, Krstić D, Oliver-Martos B, Martínez-Cáceres E, Jakasa I, Gajski G, Brun V, Kyriacou K, Burzynska-Pedziwiatr I, Wozniak LA, Nierkens S, Pascual García C, Katrlik J, Bojic-Trbojevic Z, Vacek J, Llorente A, Antohe F, Suica V, Suarez G, t'Kindt R, Martin P, Penque D, Martins IL et al. (2020)
    Analytical techniques for multiplex analysis of protein biomarkers
    Expert Rev Proteomics, 17 (4), 257-273
    DOI 10.1080/14789450.2020.1763174, PubMed 32427033
  38. Vietri M, Schultz SW, Bellanger A, Jones CM, Petersen LI, Raiborg C, Skarpen E, Pedurupillay CRJ, Kjos I, Kip E, Timmer R, Jain A, Collas P, Knorr RL, Grellscheid SN, Kusumaatmaja H, Brech A, Micci F, Stenmark H, Campsteijn C (2020)
    Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
    Nat Cell Biol, 22 (7), 856-867
    DOI 10.1038/s41556-020-0537-5, PubMed 32601372
  39. Welsh JA, van der Pol E, Bettin BA, Carter DRF, Hendrix A, Lenassi M, Langlois MA, Llorente A, van de Nes AS, Nieuwland R, Tang V, Wang L, Witwer KW, Jones JC (2020)
    Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration
    J Extracell Vesicles, 9 (1), 1816641
    DOI 10.1080/20013078.2020.1816641, PubMed 33062218
  40. Wong JJW, Berstad MB, Fremstedal ASV, Berg K, Patzke S, Sørensen V, Peng Q, Selbo PK, Weyergang A (2020)
    Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy
    Cancers (Basel), 12 (2)
    DOI 10.3390/cancers12020417, PubMed 32053965
  41. Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
    STEEP mediates STING ER exit and activation of signaling
    Nat Immunol, 21 (8), 868-879
    DOI 10.1038/s41590-020-0730-5, PubMed 32690950
  42. Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
    Author Correction: STEEP mediates STING ER exit and activation of signaling
    Nat Immunol, 21 (11), 1468-1469
    DOI 10.1038/s41590-020-0803-5, PubMed 32929276

Publications 2019

  1. Brison O, El-Hilali S, Azar D, Koundrioukoff S, Schmidt M, Nähse V, Jaszczyszyn Y, Lachages AM, Dutrillaux B, Thermes C, Debatisse M, Chen CL (2019)
    Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide
    Nat Commun, 10 (1), 5693
    DOI 10.1038/s41467-019-13674-5, PubMed 31836700
  2. Dillard C, Rusten TE (2019)
    Cell Competition Triggers Suicide by Autophagy
    Dev Cell, 51 (1), 4-5
    DOI 10.1016/j.devcel.2019.09.014, PubMed 31593651
  3. Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE et al. (2019)
    NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
    Nat Commun, 10 (1), 5284
    DOI 10.1038/s41467-019-13172-8, PubMed 31754102
  4. Frikstad KM, Molinari E, Thoresen M, Ramsbottom SA, Hughes F, Letteboer SJF, Gilani S, Schink KO, Stokke T, Geimer S, Pedersen LB, Giles RH, Akhmanova A, Roepman R, Sayer JA, Patzke S (2019)
    A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
    Cell Rep, 28 (7), 1907-1922.e6
    DOI 10.1016/j.celrep.2019.07.025, PubMed 31412255
  5. Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ (2019)
    Remodeling of secretory lysosomes during education tunes functional potential in NK cells
    Nat Commun, 10 (1), 514
    DOI 10.1038/s41467-019-08384-x, PubMed 30705279
  6. Hoem G, Bowitz Larsen K, Øvervatn A, Brech A, Lamark T, Sjøttem E, Johansen T (2019)
    The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS
    Front Genet, 10, 249
    DOI 10.3389/fgene.2019.00249, PubMed 30984240
  7. Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen JC, Eibes S, Maiani E, Harder LM, Wesch N, Foged MM, Maeda K, Nazio F, de la Ballina LR, Dötsch V, Brech A, Frankel LB, Jäättelä M, Locatelli F, Barisic M, Andersen JS, Bekker-Jensen S, Lund AH, Rogov VV, Papaleo E et al. (2019)
    Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites
    Nat Commun, 10 (1), 4176
    DOI 10.1038/s41467-019-12094-9, PubMed 31519908
  8. Khezri R, Rusten TE (2019)
    Autophagy and Tumorigenesis in Drosophila
    Adv Exp Med Biol, 1167, 113-127
    DOI 10.1007/978-3-030-23629-8_7, PubMed 31520352
  9. Khezri R, Rusten TE (2019)
    Correction to: Autophagy and Tumorigenesis in Drosophila
    Adv Exp Med Biol, 1167, C1
    DOI 10.1007/978-3-030-23629-8_15, PubMed 33306185
  10. Kumar S, Gu Y, Abudu YP, Bruun JA, Jain A, Farzam F, Mudd M, Anonsen JH, Rusten TE, Kasof G, Ktistakis N, Lidke KA, Johansen T, Deretic V (2019)
    Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation
    Dev Cell, 49 (1), 130-144.e6
    DOI 10.1016/j.devcel.2019.01.027, PubMed 30827897
  11. Lie-Jensen A, Ivanauskiene K, Malerød L, Jain A, Tan KW, Laerdahl JK, Liestøl K, Stenmark H, Haglund K (2019)
    Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
    Curr Biol, 29 (20), 3538-3548.e7
    DOI 10.1016/j.cub.2019.09.025, PubMed 31607533
  12. Luhr M, Torgersen ML, Szalai P, Hashim A, Brech A, Staerk J, Engedal N (2019)
    The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress
    J Biol Chem, 294 (20), 8197-8217
    DOI 10.1074/jbc.RA118.002829, PubMed 30926605
  13. Mehto S, Jena KK, Nath P, Chauhan S, Kolapalli SP, Das SK, Sahoo PK, Jain A, Taylor GA, Chauhan S (2019)
    The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy
    Mol Cell, 73 (3), 429-445.e7
    DOI 10.1016/j.molcel.2018.11.018, PubMed 30612879
  14. Moghimi SM, Simberg D, Skotland T, Yaghmur A, Hunter AC (2019)
    The Interplay Between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses
    J Pharmacol Exp Ther, 370 (3), 581-592
    DOI 10.1124/jpet.119.258012, PubMed 30940695
  15. Nguéa P A, Robertson J, Herrera MC, Chymkowitch P, Enserink JM (2019)
    Desumoylation of RNA polymerase III lies at the core of the Sumo stress response in yeast
    J Biol Chem, 294 (49), 18784-18795
    DOI 10.1074/jbc.RA119.009721, PubMed 31676685
  16. Palomo-Guerrero M, Fadó R, Casas M, Pérez-Montero M, Baena M, Helmer PO, Domínguez JL, Roig A, Serra D, Hayen H, Stenmark H, Raiborg C, Casals N (2019)
    Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
    Elife, 8
    DOI 10.7554/eLife.51063, PubMed 31868590
  17. Pandya AD, Jäger E, Bagheri Fam S, Höcherl A, Jäger A, Sincari V, Nyström B, Štěpánek P, Skotland T, Sandvig K, Hrubý M, Mælandsmo GM (2019)
    Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy
    Int J Nanomedicine, 14, 6269-6285
    DOI 10.2147/IJN.S208938, PubMed 31496685
  18. Prikrylova T, Robertson J, Ferrucci F, Konorska D, Aanes H, Manaf A, Zhang B, Vågbø CB, Kuśnierczyk A, Gilljam KM, Løvkvam-Køster C, Otterlei M, Dahl JA, Enserink J, Klungland A, Robertson AB (2019)
    5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
    Sci Rep, 9 (1), 11065
    DOI 10.1038/s41598-019-47528-3, PubMed 31363131
  19. Pölönen P, Jawahar Deen A, Leinonen HM, Jyrkkänen HK, Kuosmanen S, Mononen M, Jain A, Tuomainen T, Pasonen-Seppänen S, Hartikainen JM, Mannermaa A, Nykter M, Tavi P, Johansen T, Heinäniemi M, Levonen AL (2019)
    Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma
    Oncogene, 38 (50), 7473-7490
    DOI 10.1038/s41388-019-0956-6, PubMed 31444413
  20. Russell AE, Sneider A, Witwer KW, Bergese P, Bhattacharyya SN, Cocks A, Cocucci E, Erdbrügger U, Falcon-Perez JM, Freeman DW, Gallagher TM, Hu S, Huang Y, Jay SM, Kano SI, Lavieu G, Leszczynska A, Llorente AM, Lu Q, Mahairaki V, Muth DC, Noren Hooten N, Ostrowski M, Prada I, Sahoo S et al. (2019)
    Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop
    J Extracell Vesicles, 8 (1), 1684862
    DOI 10.1080/20013078.2019.1684862, PubMed 31762963
  21. Shoemaker CJ, Huang TQ, Weir NR, Polyakov NJ, Schultz SW, Denic V (2019)
    CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor
    PLoS Biol, 17 (4), e2007044
    DOI 10.1371/journal.pbio.2007044, PubMed 30933966
  22. Skjesol A, Yurchenko M, Bösl K, Gravastrand C, Nilsen KE, Grøvdal LM, Agliano F, Patane F, Lentini G, Kim H, Teti G, Kumar Sharma A, Kandasamy RK, Sporsheim B, Starheim KK, Golenbock DT, Stenmark H, McCaffrey M, Espevik T, Husebye H (2019)
    The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
    PLoS Pathog, 15 (3), e1007684
    DOI 10.1371/journal.ppat.1007684, PubMed 30883606
  23. Skotland T, Sandvig K (2019)
    The role of PS 18:0/18:1 in membrane function
    Nat Commun, 10 (1), 2752
    DOI 10.1038/s41467-019-10711-1, PubMed 31227693
  24. Sneeggen M, Pedersen NM, Campsteijn C, Haugsten EM, Stenmark H, Schink KO (2019)
    WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
    Nat Commun, 10 (1), 2850
    DOI 10.1038/s41467-019-10794-w, PubMed 31253801
  25. Sneeggen M, Schink KO, Stenmark H (2019)
    Tumor suppression by control of matrix metalloproteinase recycling
    Mol Cell Oncol, 6 (6), e1646606
    DOI 10.1080/23723556.2019.1646606, PubMed 31692886
  26. Sowa-Rogozińska N, Sominka H, Nowakowska-Gołacka J, Sandvig K, Słomińska-Wojewódzka M (2019)
    Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin
    Toxins (Basel), 11 (6)
    DOI 10.3390/toxins11060350, PubMed 31216687
  27. Szwed M, Sønstevold T, Øverbye A, Engedal N, Grallert B, Mørch Ý, Sulheim E, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2019)
    Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
    Nanotoxicology, 13 (6), 761-782
    DOI 10.1080/17435390.2019.1576238, PubMed 30760074
  28. Szybowska P, Kostas M, Wesche J, Wiedlocha A, Haugsten EM (2019)
    Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway
    Cells, 8 (6)
    DOI 10.3390/cells8060518, PubMed 31146385
  29. Tancini B, Buratta S, Sagini K, Costanzi E, Delo F, Urbanelli L, Emiliani C (2019)
    Insight into the Role of Extracellular Vesicles in Lysosomal Storage Disorders
    Genes (Basel), 10 (7)
    DOI 10.3390/genes10070510, PubMed 31284546
  30. Theodossiou TA, Ali M, Grigalavicius M, Grallert B, Dillard P, Schink KO, Olsen CE, Wälchli S, Inderberg EM, Kubin A, Peng Q, Berg K (2019)
    Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
    NPJ Breast Cancer, 5, 13
    DOI 10.1038/s41523-019-0108-8, PubMed 30993194
  31. Vietri M, Radulovic M, Stenmark H (2019)
    The many functions of ESCRTs
    Nat Rev Mol Cell Biol, 21 (1), 25-42
    DOI 10.1038/s41580-019-0177-4, PubMed 31705132
  32. Zakrzewska M, Opalinski L, Haugsten EM, Otlewski J, Wiedlocha A (2019)
    Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling
    Int J Mol Sci, 20 (8)
    DOI 10.3390/ijms20081826, PubMed 31013829
  33. Zhang B, Ayuda-Durán P, Piechaczyk L, Fløisand Y, Safont MM, Karlsen IT, Fandalyuk Z, Tadele D, van Mierlo P, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM (2019)
    GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
    Haematologica, 104 (5), e229
    DOI 10.3324/haematol.2019.220533, PubMed 31040234
  34. Zhen Y, Spangenberg H, Munson MJ, Brech A, Schink KO, Tan KW, Sørensen V, Wenzel EM, Radulovic M, Engedal N, Simonsen A, Raiborg C, Stenmark H (2019)
    ESCRT-mediated phagophore sealing during mitophagy
    Autophagy, 16 (5), 826-841
    DOI 10.1080/15548627.2019.1639301, PubMed 31366282

Publications 2018

  1. Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2018)
    Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft
    J Control Release, 293, 183-192
    DOI 10.1016/j.jconrel.2018.11.029, PubMed 30529259
  2. Herrera M, Llorens C, Rodríguez M, Herrera A, Ramos R, Gil B, Candia A, Larriba MJ, Garre P, Earl J, Rodríguez-Garrote M, Caldés T, Bonilla F, Carrato A, García-Barberán V, Peña C (2018)
    Differential distribution and enrichment of non-coding RNAs in exosomes from normal and Cancer-associated fibroblasts in colorectal cancer
    Mol Cancer, 17 (1), 114
    DOI 10.1186/s12943-018-0863-4, PubMed 30075793
  3. Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
    Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
    Nucleic Acids Res, 46 (22), 11698-11711
    DOI 10.1093/nar/gky846, PubMed 30247619
  4. Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
    Corrigendum: Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
    Nucleic Acids Res, 46 (22), 12188-12189
    DOI 10.1093/nar/gky1102, PubMed 30395271
  5. Hurem S, Gomes T, Brede DA, Mayer I, Lobert VH, Mutoloki S, Gutzkow KB, Teien HC, Oughton D, Aleström P, Lyche JL (2018)
    Gamma irradiation during gametogenesis in young adult zebrafish causes persistent genotoxicity and adverse reproductive effects
    Ecotoxicol Environ Saf, 154, 19-26
    DOI 10.1016/j.ecoenv.2018.02.031, PubMed 29453161
  6. Kostas M, Haugsten EM, Zhen Y, Sørensen V, Szybowska P, Fiorito E, Lorenz S, Jones N, de Souza GA, Wiedlocha A, Wesche J (2018)
    Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
    Mol Cell Proteomics, 17 (5), 850-870
    DOI 10.1074/mcp.RA117.000538, PubMed 29371290
  7. Kostas M, Lampart A, Bober J, Wiedlocha A, Tomala J, Krowarsch D, Otlewski J, Zakrzewska M (2018)
    Translocation of Exogenous FGF1 and FGF2 Protects the Cell against Apoptosis Independently of Receptor Activation
    J Mol Biol, 430 (21), 4087-4101
    DOI 10.1016/j.jmb.2018.08.004, PubMed 30099027
  8. Kruitwagen T, Chymkowitch P, Denoth-Lippuner A, Enserink J, Barral Y (2018)
    Centromeres License the Mitotic Condensation of Yeast Chromosome Arms
    Cell, 175 (3), 780-795.e15
    DOI 10.1016/j.cell.2018.09.012, PubMed 30318142
  9. Kumar S, Jain A, Farzam F, Jia J, Gu Y, Choi SW, Mudd MH, Claude-Taupin A, Wester MJ, Lidke KA, Rusten TE, Deretic V (2018)
    Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins
    J Cell Biol, 217 (3), 997-1013
    DOI 10.1083/jcb.201708039, PubMed 29420192
  10. Malerød L, Le Borgne R, Lie-Jensen A, Eikenes ÅH, Brech A, Liestøl K, Stenmark H, Haglund K (2018)
    Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics
    EMBO J, 37 (13)
    DOI 10.15252/embj.201797741, PubMed 29858227
  11. Mejlvang J, Olsvik H, Svenning S, Bruun JA, Abudu YP, Larsen KB, Brech A, Hansen TE, Brenne H, Hansen T, Stenmark H, Johansen T (2018)
    Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
    J Cell Biol, 217 (10), 3640-3655
    DOI 10.1083/jcb.201711002, PubMed 30018090
  12. Norum JH, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, Sørlie T (2018)
    The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology
    Biol Res, 51 (1), 3
    DOI 10.1186/s40659-017-0151-6, PubMed 29316982
  13. Nouri H, Monnier AF, Fossum-Raunehaug S, Maciag-Dorszynska M, Cabin-Flaman A, Képès F, Wegrzyn G, Szalewska-Palasz A, Norris V, Skarstad K, Janniere L (2018)
    Multiple links connect central carbon metabolism to DNA replication initiation and elongation in Bacillus subtilis
    DNA Res, 25 (6), 641-653
    DOI 10.1093/dnares/dsy031, PubMed 30256918
  14. Olsvik HL, Svenning S, Abudu YP, Brech A, Stenmark H, Johansen T, Mejlvang J (2018)
    Endosomal microautophagy is an integrated part of the autophagic response to amino acid starvation
    Autophagy, 15 (1), 182-183
    DOI 10.1080/15548627.2018.1532265, PubMed 30295124
  15. Osteikoetxea X, Benke M, Rodriguez M, Pálóczi K, Sódar BW, Szvicsek Z, Szabó-Taylor K, Vukman KV, Kittel Á, Wiener Z, Vékey K, Harsányi L, Szűcs Á, Turiák L, Buzás EI (2018)
    Detection and proteomic characterization of extracellular vesicles in human pancreatic juice
    Biochem Biophys Res Commun, 499 (1), 37-43
    DOI 10.1016/j.bbrc.2018.03.107, PubMed 29550476
  16. Popēna I, Ābols A, Saulīte L, Pleiko K, Zandberga E, Jēkabsons K, Endzeliņš E, Llorente A, Linē A, Riekstiņa U (2018)
    Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages
    Cell Commun Signal, 16 (1), 17
    DOI 10.1186/s12964-018-0229-y, PubMed 29690889
  17. Radulovic M, Schink KO, Wenzel EM, Nähse V, Bongiovanni A, Lafont F, Stenmark H (2018)
    ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival
    EMBO J, 37 (21)
    DOI 10.15252/embj.201899753, PubMed 30314966
  18. Radulovic M, Stenmark H (2018)
    ESCRTs in membrane sealing
    Biochem Soc Trans, 46 (4), 773-778
    DOI 10.1042/BST20170435, PubMed 29903934
  19. Sandvig K, Kavaliauskiene S, Skotland T (2018)
    Clathrin-independent endocytosis: an increasing degree of complexity
    Histochem Cell Biol, 150 (2), 107-118
    DOI 10.1007/s00418-018-1678-5, PubMed 29774430
  20. Skotland T, Hessvik NP, Sandvig K, Llorente A (2018)
    Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology
    J Lipid Res, 60 (1), 9-18
    DOI 10.1194/jlr.R084343, PubMed 30076207
  21. Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E et al. (2018)
    Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
    J Extracell Vesicles, 7 (1), 1535750
    DOI 10.1080/20013078.2018.1535750, PubMed 30637094
  22. Vietri M, Stenmark H (2018)
    Orchestrating Nuclear Envelope Sealing during Mitosis
    Dev Cell, 47 (5), 541-542
    DOI 10.1016/j.devcel.2018.11.020, PubMed 30513298
  23. Wenzel EM, Schultz SW, Schink KO, Pedersen NM, Nähse V, Carlson A, Brech A, Stenmark H, Raiborg C (2018)
    Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
    Nat Commun, 9 (1), 2932
    DOI 10.1038/s41467-018-05345-8, PubMed 30050131
  24. Weyergang A, Fremstedal AS, Skarpen E, Peng Q, Mohamedali KA, Eng MS, Cheung LH, Rosenblum MG, Waltenberger J, Berg K (2018)
    Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy
    J Control Release, 288, 161-172
    DOI 10.1016/j.jconrel.2018.09.005, PubMed 30217739
  25. Zhang B, Durán PA, Piechaczyk L, Fløisand Y, Safont MMS, Karlsen IT, Fandalyuk Z, Tadele D, Mierlo PV, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM, Bjørn Tore Gjertsen Group, Emmet McCormack Group (2018)
    GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
    Haematologica, Online ahead of print (in press) (Retracted)
    DOI 10.3324/haematol.2018.189399, PubMed 29748445
  26. Zhen Y, Haugsten EM, Singh SK, Wesche J (2018)
    Proximity Labeling by a Recombinant APEX2-FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4
    Biochemistry, 57 (26), 3807-3816
    DOI 10.1021/acs.biochem.8b00120, PubMed 29812912

Publications 2017

  1. Ailte I, Lingelem AB, Kvalvaag AS, Kavaliauskiene S, Brech A, Koster G, Dommersnes PG, Bergan J, Skotland T, Sandvig K (2017)
    Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
    Traffic, 18 (3), 176-191
    DOI 10.1111/tra.12468, PubMed 28067430
  2. Boye E, Skotland T, Østerud B, Nissen-Meyer J (2017)
    Doping and drug testing: Anti-doping work must be transparent and adhere to good scientific practices to ensure public trust
    EMBO Rep, 18 (3), 351-354
    DOI 10.15252/embr.201643540, PubMed 28167676
  3. Cambier S, Røgeberg M, Georgantzopoulou A, Serchi T, Karlsson C, Verhaegen S, Iversen TG, Guignard C, Kruszewski M, Hoffmann L, Audinot JN, Ropstad E, Gutleb AC (2017)
    Fate and effects of silver nanoparticles on early life-stage development of zebrafish (Danio rerio) in comparison to silver nitrate
    Sci Total Environ, 610-611, 972-982
    DOI 10.1016/j.scitotenv.2017.08.115, PubMed 28838034
  4. Chymkowitch P, Enserink JM (2017)
    Regulation of tRNA synthesis by posttranslational modifications of RNA polymerase III subunits
    Biochim Biophys Acta Gene Regul Mech, 1861 (4), 310-319
    DOI 10.1016/j.bbagrm.2017.11.001, PubMed 29127063
  5. Chymkowitch P, Nguéa P A, Aanes H, Robertson J, Klungland A, Enserink JM (2017)
    TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity
    Proc Natl Acad Sci U S A, 114 (5), 1039-1044
    DOI 10.1073/pnas.1615093114, PubMed 28096404
  6. Endzeliņš E, Berger A, Melne V, Bajo-Santos C, Soboļevska K, Ābols A, Rodriguez M, Šantare D, Rudņickiha A, Lietuvietis V, Llorente A, Linē A (2017)
    Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients
    BMC Cancer, 17 (1), 730
    DOI 10.1186/s12885-017-3737-z, PubMed 29121858
  7. Enserink J, Nguéa P A, Chymkowitch P (2017)
    Anabolic transcription: Secrets of the sumo diet
    Cell Cycle, 16 (7), 593-594
    DOI 10.1080/15384101.2017.1294945, PubMed 28278057
  8. Enserink JM (2017)
    Regulation of Cellular Processes by SUMO: Understudied Topics
    Adv Exp Med Biol, 963, 89-97
    DOI 10.1007/978-3-319-50044-7_5, PubMed 28197907
  9. Enserink JM (2017)
    Sumo during stress: When transcription takes a pause (comment on DOI.10.1002/bies.201600263)
    Bioessays, 39 (6)
    DOI 10.1002/bies.201700065, PubMed 28464310
  10. Flåtten I, Helgesen E, Pedersen IB, Waldminghaus T, Rothe C, Taipale R, Johnsen L, Skarstad K (2017)
    Phenotypes of dnaXE145A Mutant Cells Indicate that the Escherichia coli Clamp Loader Has a Role in the Restart of Stalled Replication Forks
    J Bacteriol, 199 (24)
    DOI 10.1128/JB.00412-17, PubMed 28947673
  11. Fosdahl AM, Dietrich M, Schink KO, Malik MS, Skeie M, Bertelsen V, Stang E (2017)
    ErbB3 interacts with Hrs and is sorted to lysosomes for degradation
    Biochim Biophys Acta Mol Cell Res, 1864 (12), 2241-2252
    DOI 10.1016/j.bbamcr.2017.08.011, PubMed 28867611
  12. Hardes K, Ivanova T, Thaa B, McInerney GM, Klokk TI, Sandvig K, Künzel S, Lindberg I, Steinmetzer T (2017)
    Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin
    ChemMedChem, 12 (8), 613-620
    DOI 10.1002/cmdc.201700108, PubMed 28334511
  13. Hessvik NP, Llorente A (2017)
    Current knowledge on exosome biogenesis and release
    Cell Mol Life Sci, 75 (2), 193-208
    DOI 10.1007/s00018-017-2595-9, PubMed 28733901
  14. Hong Z, Pedersen NM, Wang L, Torgersen ML, Stenmark H, Raiborg C (2017)
    PtdIns3P controls mTORC1 signaling through lysosomal positioning
    J Cell Biol, 216 (12), 4217-4233
    DOI 10.1083/jcb.201611073, PubMed 29030394
  15. Katheder NS, Khezri R, O'Farrell F, Schultz SW, Jain A, Rahman MM, Schink KO, Theodossiou TA, Johansen T, Juhász G, Bilder D, Brech A, Stenmark H, Rusten TE (2017)
    Microenvironmental autophagy promotes tumour growth
    Nature, 541 (7637), 417-420
    DOI 10.1038/nature20815, PubMed 28077876
  16. Katheder NS, Rusten TE (2017)
    Microenvironment and tumors-a nurturing relationship
    Autophagy, 13 (7), 1241-1243
    DOI 10.1080/15548627.2017.1310361, PubMed 28632995
  17. Kavaliauskiene S, Dyve Lingelem AB, Skotland T, Sandvig K (2017)
    Protection against Shiga Toxins
    Toxins (Basel), 9 (2)
    DOI 10.3390/toxins9020044, PubMed 28165371
  18. Krzyscik MA, Zakrzewska M, Sørensen V, Sokolowska-Wedzina A, Lobocki M, Swiderska KW, Krowarsch D, Wiedlocha A, Otlewski J (2017)
    Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors
    ACS Omega, 2 (7), 3792-3805
    DOI 10.1021/acsomega.7b00116, PubMed 30023704
  19. Labieniec-Watala M, Szwed M, Hertel J, Wisnik E (2017)
    Low Concentrations of Cationic PAMAM Dendrimers Affect Lymphocyte Respiration in In vitro Studies
    Curr Pharm Biotechnol, 18 (2), 150-157
    DOI 10.2174/1389201017666161229153018, PubMed 28034293
  20. Lång A, Eriksson J, Schink KO, Lång E, Blicher P, Połeć A, Brech A, Dalhus B, Bøe SO (2017)
    Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites
    Nucleus, 8 (4), 404-420
    DOI 10.1080/19491034.2017.1306161, PubMed 28402725
  21. Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V (2017)
    Correction: TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
    J Cell Sci, 130 (6), 1194
    DOI 10.1242/jcs.202499, PubMed 28298613
  22. Manna D, Pust S, Torgersen ML, Cordara G, Künzler M, Krengel U, Sandvig K (2017)
    Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis
    PLoS One, 12 (1), e0170716
    DOI 10.1371/journal.pone.0170716, PubMed 28114329
  23. O'Farrell F, Lobert VH, Sneeggen M, Jain A, Katheder NS, Wenzel EM, Schultz SW, Tan KW, Brech A, Stenmark H, Rusten TE (2017)
    Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation
    Nat Cell Biol, 19 (12), 1412-1423
    DOI 10.1038/ncb3631, PubMed 29084199
  24. Olsen CE, Weyergang A, Edwards VT, Berg K, Brech A, Weisheit S, Høgset A, Selbo PK (2017)
    Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
    Biochem Pharmacol, 144, 63-77
    DOI 10.1016/j.bcp.2017.08.002, PubMed 28784290
  25. Pathan M, Keerthikumar S, Chisanga D, Alessandro R, Ang CS, Askenase P, Batagov AO, Benito-Martin A, Camussi G, Clayton A, Collino F, Di Vizio D, Falcon-Perez JM, Fonseca P, Fonseka P, Fontana S, Gho YS, Hendrix A, Hoen EN, Iraci N, Kastaniegaard K, Kislinger T, Kowal J, Kurochkin IV, Leonardi T et al. (2017)
    A novel community driven software for functional enrichment analysis of extracellular vesicles data
    J Extracell Vesicles, 6 (1), 1321455
    DOI 10.1080/20013078.2017.1321455, PubMed 28717418
  26. Pedersen IB, Helgesen E, Flåtten I, Fossum-Raunehaug S, Skarstad K (2017)
    SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms
    Nucleic Acids Res, 45 (11), 6471-6485
    DOI 10.1093/nar/gkx263, PubMed 28407100
  27. Pietarinen PO, Eide CA, Ayuda-Durán P, Potdar S, Kuusanmäki H, Andersson EI, Mpindi JP, Pemovska T, Kontro M, Heckman CA, Kallioniemi O, Wennerberg K, Hjorth-Hansen H, Druker BJ, Enserink JM, Tyner JW, Mustjoki S, Porkka K (2017)
    Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors
    Oncotarget, 8 (14), 22606-22615
    DOI 10.18632/oncotarget.15146, PubMed 28186983
  28. Rahman MM, Franch-Marro X, Maestro JL, Martin D, Casali A (2017)
    Local Juvenile Hormone activity regulates gut homeostasis and tumor growth in adult Drosophila
    Sci Rep, 7 (1), 11677
    DOI 10.1038/s41598-017-11199-9, PubMed 28916802
  29. Raiborg C, Schink KO, Stenmark H (2017)
    Suppressing mTORC1 on the lysosome
    EMBO J, 36 (13), 1809-1810
    DOI 10.15252/embj.201797469, PubMed 28623241
  30. Sadovska L, Zandberga E, Sagini K, Jēkabsons K, Riekstiņa U, Kalniņa Z, Llorente A, Linē A (2017)
    A novel 3D heterotypic spheroid model for studying extracellular vesicle-mediated tumour and immune cell communication
    Biochem Biophys Res Commun, 495 (2), 1930-1935
    DOI 10.1016/j.bbrc.2017.12.072, PubMed 29248729
  31. Simm R, Kvalvaag AS, van Deurs B, Lindbäck T, Sandvig K (2017)
    Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network
    Exp Cell Res, 357 (1), 67-78
    DOI 10.1016/j.yexcr.2017.04.025, PubMed 28450044
  32. Skotland T (2017)
    Injection of nanoparticles into cloven-hoof animals: Asking for trouble
    Theranostics, 7 (19), 4877-4878
    DOI 10.7150/thno.22420, PubMed 29187910
  33. Skotland T, Sandvig K, Llorente A (2017)
    Lipids in exosomes: Current knowledge and the way forward
    Prog Lipid Res, 66, 30-41
    DOI 10.1016/j.plipres.2017.03.001, PubMed 28342835
  34. Sulheim E, Iversen TG, To Nakstad V, Klinkenberg G, Sletta H, Schmid R, Hatletveit AR, Wågbø AM, Sundan A, Skotland T, Sandvig K, Mørch Ý (2017)
    Cytotoxicity of Poly(Alkyl Cyanoacrylate) Nanoparticles
    Int J Mol Sci, 18 (11)
    DOI 10.3390/ijms18112454, PubMed 29156588
  35. Søreng K, Knævelsrud H, Holland P, Simonsen A (2017)
    HS1BP3 inhibits autophagy by regulation of PLD1
    Autophagy, 13 (5), 985-986
    DOI 10.1080/15548627.2017.1291483, PubMed 28318354
  36. Taubenschmid J, Stadlmann J, Jost M, Klokk TI, Rillahan CD, Leibbrandt A, Mechtler K, Paulson JC, Jude J, Zuber J, Sandvig K, Elling U, Marquardt T, Thiel C, Koerner C, Penninger JM (2017)
    A vital sugar code for ricin toxicity
    Cell Res, 27 (11), 1351-1364
    DOI 10.1038/cr.2017.116, PubMed 28925387
  37. Thorvaldsen TE (2017)
    Targeting Tankyrase to Fight WNT-dependent Tumours
    Basic Clin Pharmacol Toxicol, 121 (2), 81-88
    DOI 10.1111/bcpt.12786, PubMed 28371398
  38. Thorvaldsen TE, Pedersen NM, Wenzel EM, Stenmark H (2017)
    Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation
    PLoS One, 12 (1), e0170508
    DOI 10.1371/journal.pone.0170508, PubMed 28107521
  39. Totland MZ, Bergsland CH, Fykerud TA, Knudsen LM, Rasmussen NL, Eide PW, Yohannes Z, Sørensen V, Brech A, Lothe RA, Leithe E (2017)
    The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions
    J Cell Sci, 130 (17), 2867-2882
    DOI 10.1242/jcs.202408, PubMed 28733455
  40. Tusco R, Jacomin AC, Jain A, Penman BS, Larsen KB, Johansen T, Nezis IP (2017)
    Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
    Nat Commun, 8 (1), 1264
    DOI 10.1038/s41467-017-01287-9, PubMed 29097655
  41. Vestad B, Llorente A, Neurauter A, Phuyal S, Kierulf B, Kierulf P, Skotland T, Sandvig K, Haug KBF, Øvstebø R (2017)
    Size and concentration analyses of extracellular vesicles by nanoparticle tracking analysis: a variation study
    J Extracell Vesicles, 6 (1), 1344087
    DOI 10.1080/20013078.2017.1344087, PubMed 28804597
  42. Zimmermann C, Garcia I, Omerzu M, Chymkowitch P, Zhang B, Enserink JM (2017)
    Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28
    G3 (Bethesda), 7 (6), 1753-1766
    DOI 10.1534/g3.117.042317, PubMed 28428242
  43. Øverbye A, Holsæter AM, Markus F, Škalko-Basnet N, Iversen TG, Torgersen ML, Sønstevold T, Engebraaten O, Flatmark K, Mælandsmo GM, Skotland T, Sandvig K (2017)
    Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide
    Oncotarget, 8 (44), 76921-76934
    DOI 10.18632/oncotarget.20217, PubMed 29100358

Publications 2016

  1. Ailte I, Lingelem AB, Kavaliauskiene S, Bergan J, Kvalvaag AS, Myrann AG, Skotland T, Sandvig K (2016)
    Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding
    Sci Rep, 6, 30336
    DOI 10.1038/srep30336, PubMed 27458147
  2. Asp N, Kvalvaag A, Sandvig K, Pust S (2016)
    Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins
    Oncotarget, 7 (18), 25443-60
    DOI 10.18632/oncotarget.8327, PubMed 27029001
  3. Bober J, Olsnes S, Kostas M, Bogacz M, Zakrzewska M, Otlewski J (2016)
    Identification of new FGF1 binding partners-Implications for its intracellular function
    IUBMB Life, 68 (3), 242-51
    DOI 10.1002/iub.1480, PubMed 26840910
  4. Campsteijn C, Vietri M, Stenmark H (2016)
    Novel ESCRT functions in cell biology: spiraling out of control?
    Curr Opin Cell Biol, 41, 1-8
    DOI 10.1016/j.ceb.2016.03.008, PubMed 27031044
  5. Christ L, Raiborg C, Wenzel EM, Campsteijn C, Stenmark H (2016)
    Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery
    Trends Biochem Sci, 42 (1), 42-56
    DOI 10.1016/j.tibs.2016.08.016, PubMed 27669649
  6. Christ L, Wenzel EM, Liestøl K, Raiborg C, Campsteijn C, Stenmark H (2016)
    ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission
    J Cell Biol, 212 (5), 499-513
    DOI 10.1083/jcb.201507009, PubMed 26929449
  7. Cordara G, van Eerde A, Grahn EM, Winter HC, Goldstein IJ, Krengel U (2016)
    An Unusual Member of the Papain Superfamily: Mapping the Catalytic Cleft of the Marasmius oreades agglutinin (MOA) with a Caspase Inhibitor
    PLoS One, 11 (2), e0149407
    DOI 10.1371/journal.pone.0149407, PubMed 26901797
  8. Endzeliņš E, Melne V, Kalniņa Z, Lietuvietis V, Riekstiņa U, Llorente A, Linē A (2016)
    Diagnostic, prognostic and predictive value of cell-free miRNAs in prostate cancer: a systematic review
    Mol Cancer, 15 (1), 41
    DOI 10.1186/s12943-016-0523-5, PubMed 27189160
  9. Fais S, O'Driscoll L, Borras FE, Buzas E, Camussi G, Cappello F, Carvalho J, Cordeiro da Silva A, Del Portillo H, El Andaloussi S, Ficko Trček T, Furlan R, Hendrix A, Gursel I, Kralj-Iglic V, Kaeffer B, Kosanovic M, Lekka ME, Lipps G, Logozzi M, Marcilla A, Sammar M, Llorente A, Nazarenko I, Oliveira C et al. (2016)
    Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine
    ACS Nano, 10 (4), 3886-99
    DOI 10.1021/acsnano.5b08015, PubMed 26978483
  10. Fykerud TA, Knudsen LM, Totland MZ, Sørensen V, Dahal-Koirala S, Lothe RA, Brech A, Leithe E (2016)
    Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding
    Cell Cycle, 15 (21), 2943-2957
    DOI 10.1080/15384101.2016.1231280, PubMed 27625181
  11. Halsne R, Tandberg JI, Lobert VH, Østby GC, Thoen E, Ropstad E, Verhaegen S (2016)
    Effects of perfluorinated alkyl acids on cellular responses of MCF-10A mammary epithelial cells in monolayers and on acini formation in vitro
    Toxicol Lett, 259, 95-107
    DOI 10.1016/j.toxlet.2016.08.004, PubMed 27511595
  12. Haugsten EM, Sørensen V, Kunova Bosakova M, de Souza GA, Krejci P, Wiedlocha A, Wesche J (2016)
    Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport
    J Proteome Res, 15 (10), 3841-3855
    DOI 10.1021/acs.jproteome.6b00652, PubMed 27615514
  13. Helgesen E, Fossum-Raunehaug S, Skarstad K (2016)
    Lack of the H-NS Protein Results in Extended and Aberrantly Positioned DNA during Chromosome Replication and Segregation in Escherichia coli
    J Bacteriol, 198 (8), 1305-16
    DOI 10.1128/JB.00919-15, PubMed 26858102
  14. Herrera C, Klokk TI, Cole R, Sandvig K, Mantis NJ (2016)
    A Bispecific Antibody Promotes Aggregation of Ricin Toxin on Cell Surfaces and Alters Dynamics of Toxin Internalization and Trafficking
    PLoS One, 11 (6), e0156893
    DOI 10.1371/journal.pone.0156893, PubMed 27300140
  15. Hessvik NP, Øverbye A, Brech A, Torgersen ML, Jakobsen IS, Sandvig K, Llorente A (2016)
    PIKfyve inhibition increases exosome release and induces secretory autophagy
    Cell Mol Life Sci, 73 (24), 4717-4737
    DOI 10.1007/s00018-016-2309-8, PubMed 27438886
  16. Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A (2016)
    HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
    Nat Commun, 7, 13889
    DOI 10.1038/ncomms13889, PubMed 28004827
  17. Kavaliauskiene S, Torgersen ML, Lingelem AB, Klokk TI, Lintonen T, Simolin H, Ekroos K, Skotland T, Sandvig K (2016)
    Cellular effects of fluorodeoxyglucose: Global changes in the lipidome and alteration in intracellular transport
    Oncotarget, 7 (48), 79885-79900
    DOI 10.18632/oncotarget.13089, PubMed 27829218
  18. Li Y, Hessvik NP, Danbolt NC, Holen T (2016)
    A large-scale quantitative EM study on activation of olfactory glands shows no effect of cholinergic agents
    Microscopy (Oxf), 65 (5), 438-443
    DOI 10.1093/jmicro/dfw028, PubMed 27460022
  19. Lie-Jensen A, Haglund K (2016)
    Antibody Staining in Drosophila Germaria
    Methods Mol Biol, 1457, 19-33
    DOI 10.1007/978-1-4939-3795-0_3, PubMed 27557571
  20. Lobert VH, Mouradov D, Heath JK (2016)
    Focusing the Spotlight on the Zebrafish Intestine to Illuminate Mechanisms of Colorectal Cancer
    Adv Exp Med Biol, 916, 411-37
    DOI 10.1007/978-3-319-30654-4_18, PubMed 27165364
  21. Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M (2016)
    ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors
    Sci Signal, 9 (411), ra8
    DOI 10.1126/scisignal.aad0848, PubMed 26787452
  22. Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V (2016)
    TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
    J Cell Sci, 129 (19), 3562-3573
    DOI 10.1242/jcs.190017, PubMed 27562068
  23. Nähse V, Christ L, Stenmark H, Campsteijn C (2016)
    The Abscission Checkpoint: Making It to the Final Cut
    Trends Cell Biol, 27 (1), 1-11
    DOI 10.1016/j.tcb.2016.10.001, PubMed 27810282
  24. Pedersen NM, Thorvaldsen TE, Schultz SW, Wenzel EM, Stenmark H (2016)
    Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity
    PLoS One, 11 (8), e0160507
    DOI 10.1371/journal.pone.0160507, PubMed 27482906
  25. Puvirajesinghe TM, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, Sebbagh M, Lopez M, Brech A, Finetti P, Charafe-Jauffret E, Chaffanet M, Castellano R, Restouin A, Marchetto S, Collette Y, Gonçalvès A, Macara I, Birnbaum D, Kodjabachian L, Johansen T, Borg JP (2016)
    Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer
    Nat Commun, 7, 10318
    DOI 10.1038/ncomms10318, PubMed 26754771
  26. Raiborg C, Stenmark H (2016)
    Plasma membrane repairs by small GTPase Rab3a
    J Cell Biol, 213 (6), 613-5
    DOI 10.1083/jcb.201606006, PubMed 27325788
  27. Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
    Phosphoinositides in membrane contact sites
    Biochem Soc Trans, 44 (2), 425-30
    DOI 10.1042/BST20150190, PubMed 27068950
  28. Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
    ER-endosome contact sites in endosome positioning and protrusion outgrowth
    Biochem Soc Trans, 44 (2), 441-6
    DOI 10.1042/BST20150246, PubMed 27068952
  29. Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2016)
    Data including GROMACS input files for atomistic molecular dynamics simulations of mixed, asymmetric bilayers including molecular topologies, equilibrated structures, and force field for lipids compatible with OPLS-AA parameters
    Data Brief, 7, 1171-1174
    DOI 10.1016/j.dib.2016.03.067, PubMed 27761499
  30. Schink KO, Tan KW, Stenmark H (2016)
    Phosphoinositides in Control of Membrane Dynamics
    Annu Rev Cell Dev Biol, 32, 143-171
    DOI 10.1146/annurev-cellbio-111315-125349, PubMed 27576122
  31. Schmid MR, Anderl I, Vo HT, Valanne S, Yang H, Kronhamn J, Rämet M, Rusten TE, Hultmark D (2016)
    Genetic Screen in Drosophila Larvae Links ird1 Function to Toll Signaling in the Fat Body and Hemocyte Motility
    PLoS One, 11 (7), e0159473
    DOI 10.1371/journal.pone.0159473, PubMed 27467079
  32. Skotland T (2016)
    How organizers of scientific meetings and journal editors could facilitate transfer of nanomedicine into the clinic
    Eur. J. Nanomed., 8 (1), 61-63
    DOI 10.1515/ejnm-2015-0048
  33. Skotland T, Ekroos K, Kauhanen D, Simolin H, Seierstad T, Berge V, Sandvig K, Llorente A (2016)
    Molecular lipid species in urinary exosomes as potential prostate cancer biomarkers
    Eur J Cancer, 70, 122-132
    DOI 10.1016/j.ejca.2016.10.011, PubMed 27914242
  34. Skotland T, Ekroos K, Kavaliauskiene S, Bergan J, Kauhanen D, Lintonen T, Sandvig K (2016)
    Determining the Turnover of Glycosphingolipid Species by Stable-Isotope Tracer Lipidomics
    J Mol Biol, 428 (24 Pt A), 4856-4866
    DOI 10.1016/j.jmb.2016.06.013, PubMed 27363608
  35. Sundvold H, Sundvold-Gjerstad V, Malerød-Fjeld H, Haglund K, Stenmark H, Malerød L (2016)
    Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow
    Cell Cycle, 15 (5), 628-43
    DOI 10.1080/15384101.2016.1146834, PubMed 27104745
  36. Szymanska M, Fosdahl AM, Raiborg C, Dietrich M, Liestøl K, Stang E, Bertelsen V (2016)
    Interaction with epsin 1 regulates the constitutive clathrin-dependent internalization of ErbB3
    Biochim Biophys Acta, 1863 (6 Pt A), 1179-88
    DOI 10.1016/j.bbamcr.2016.03.011, PubMed 26975582
  37. Tesikova M, Dezitter X, Nenseth HZ, Klokk TI, Mueller F, Hager GL, Saatcioglu F (2016)
    Divergent Binding and Transactivation by Two Related Steroid Receptors at the Same Response Element
    J Biol Chem, 291 (22), 11899-910
    DOI 10.1074/jbc.M115.684480, PubMed 27056330
  38. Torgersen ML, Klokk TI, Kavaliauskiene S, Klose C, Simons K, Skotland T, Sandvig K (2016)
    The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport
    Oncotarget, 7 (52), 86871-86888
    DOI 10.18632/oncotarget.13508, PubMed 27894086
  39. Vietri M, Stenmark H, Campsteijn C (2016)
    Closing a gap in the nuclear envelope
    Curr Opin Cell Biol, 40, 90-97
    DOI 10.1016/j.ceb.2016.03.001, PubMed 27016712
  40. Wang L, Skotland T, Berge V, Sandvig K, Llorente A (2016)
    Exosomal proteins as prostate cancer biomarkers in urine: From mass spectrometry discovery to immunoassay-based validation
    Eur J Pharm Sci, 98, 80-85
    DOI 10.1016/j.ejps.2016.09.023, PubMed 27664330
  41. Yermakova A, Klokk TI, O'Hara JM, Cole R, Sandvig K, Mantis NJ (2016)
    Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin's Enzymatic Subunit Interfere with Intracellular Toxin Transport
    Sci Rep, 6, 22721
    DOI 10.1038/srep22721, PubMed 26949061

Publications 2015

  1. Bauereiss A, Welzel O, Jung J, Grosse-Holz S, Lelental N, Lewczuk P, Wenzel EM, Kornhuber J, Groemer TW (2015)
    Surface Trafficking of APP and BACE in Live Cells
    Traffic, 16 (6), 655-75
    DOI 10.1111/tra.12270, PubMed 25712587
  2. Buchtova M, Chaloupkova R, Zakrzewska M, Vesela I, Cela P, Barathova J, Gudernova I, Zajickova R, Trantirek L, Martin J, Kostas M, Otlewski J, Damborsky J, Kozubik A, Wiedlocha A, Krejci P (2015)
    Instability restricts signaling of multiple fibroblast growth factors
    Cell Mol Life Sci, 72 (12), 2445-59
    DOI 10.1007/s00018-015-1856-8, PubMed 25854632
  3. Bull-Hansen B, Berstad MB, Berg K, Cao Y, Skarpen E, Fremstedal AS, Rosenblum MG, Peng Q, Weyergang A (2015)
    Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer
    Oncotarget, 6 (14), 12436-51
    DOI 10.18632/oncotarget.3814, PubMed 26002552
  4. Drießen S, Berleth N, Friesen O, Löffler AS, Böhler P, Hieke N, Stuhldreier F, Peter C, Schink KO, Schultz SW, Stenmark H, Holland P, Simonsen A, Wesselborg S, Stork B (2015)
    Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy
    Autophagy, 11 (9), 1458-70
    DOI 10.1080/15548627.2015.1067359, PubMed 26207339
  5. Dyve Lingelem AB, Hjelseth IA, Simm R, Torgersen ML, Sandvig K (2015)
    Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells
    PLoS One, 10 (5), e0129214
    DOI 10.1371/journal.pone.0129214, PubMed 26017782
  6. Egeland EV, Boye K, Pettersen SJ, Haugen MH, Øyjord T, Malerød L, Flatmark K, Mælandsmo GM (2015)
    Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes
    Clin Exp Metastasis, 32 (8), 755-67
    DOI 10.1007/s10585-015-9742-1, PubMed 26349943
  7. Eikenes ÅH, Malerød L, Christensen AL, Steen CB, Mathieu J, Nezis IP, Liestøl K, Huynh JR, Stenmark H, Haglund K (2015)
    ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo
    PLoS Genet, 11 (1), e1004904
    DOI 10.1371/journal.pgen.1004904, PubMed 25635693
  8. Eikenes ÅH, Malerød L, Lie-Jensen A, Sem Wegner C, Brech A, Liestøl K, Stenmark H, Haglund K (2015)
    Src64 controls a novel actin network required for proper ring canal formation in the Drosophila male germline
    Development, 142 (23), 4107-18
    DOI 10.1242/dev.124370, PubMed 26628094
  9. Eriksen AB, Torgersen ML, Holm KL, Abrahamsen G, Spurkland A, Moskaug JØ, Simonsen A, Blomhoff HK (2015)
    Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy
    Autophagy, 11 (3), 460-71
    DOI 10.1080/15548627.2015.1009797, PubMed 25749095
  10. Flåtten I, Fossum-Raunehaug S, Taipale R, Martinsen S, Skarstad K (2015)
    The DnaA Protein Is Not the Limiting Factor for Initiation of Replication in Escherichia coli
    PLoS Genet, 11 (6), e1005276
    DOI 10.1371/journal.pgen.1005276, PubMed 26047361
  11. Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T (2015)
    Novel Furin Inhibitors with Potent Anti-infectious Activity
    ChemMedChem, 10 (7), 1218-31
    DOI 10.1002/cmdc.201500103, PubMed 25974265
  12. Helgesen E, Fossum-Raunehaug S, Sætre F, Schink KO, Skarstad K (2015)
    Dynamic Escherichia coli SeqA complexes organize the newly replicated DNA at a considerable distance from the replisome
    Nucleic Acids Res, 43 (5), 2730-43
    DOI 10.1093/nar/gkv146, PubMed 25722374
  13. Jain A, Rusten TE, Katheder N, Elvenes J, Bruun JA, Sjøttem E, Lamark T, Johansen T (2015)
    p62/Sequestosome-1, Autophagy-related Gene 8, and Autophagy in Drosophila Are Regulated by Nuclear Factor Erythroid 2-related Factor 2 (NRF2), Independent of Transcription Factor TFEB
    J Biol Chem, 290 (24), 14945-62
    DOI 10.1074/jbc.M115.656116, PubMed 25931115
  14. Kavaliauskiene S, Skotland T, Sylvänne T, Simolin H, Klokk TI, Torgersen ML, Lingelem AB, Simm R, Ekroos K, Sandvig K (2015)
    Novel actions of 2-deoxy-D-glucose: protection against Shiga toxins and changes in cellular lipids
    Biochem J, 470 (1), 23-37
    DOI 10.1042/BJ20141562, PubMed 26251444
  15. Klokk TI, Kavaliauskiene S, Sandvig K (2015)
    Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic
    Cell Mol Life Sci, 73 (6), 1301-16
    DOI 10.1007/s00018-015-2049-1, PubMed 26407609
  16. Kymre L, Simm R, Skotland T, Sandvig K (2015)
    Different roles of the C-terminal end of Stx1A and Stx2A for AB5 complex integrity and retrograde transport of Stx in HeLa cells
    Pathog Dis, 73 (9), ftv083
    DOI 10.1093/femspd/ftv083, PubMed 26443836
  17. Le Guyon S, Simm R, Rehn M, Römling U (2015)
    Dissecting the cyclic di-guanylate monophosphate signalling network regulating motility in Salmonella enterica serovar Typhimurium
    Environ Microbiol, 17 (4), 1310-20
    DOI 10.1111/1462-2920.12580, PubMed 25059628
  18. Raiborg C, Wenzel EM, Pedersen NM, Olsvik H, Schink KO, Schultz SW, Vietri M, Nisi V, Bucci C, Brech A, Johansen T, Stenmark H (2015)
    Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth
    Nature, 520 (7546), 234-8
    DOI 10.1038/nature14359, PubMed 25855459
  19. Raiborg C, Wenzel EM, Stenmark H (2015)
    ER-endosome contact sites: molecular compositions and functions
    EMBO J, 34 (14), 1848-58
    DOI 10.15252/embj.201591481, PubMed 26041457
  20. Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2015)
    Interdigitation of long-chain sphingomyelin induces coupling of membrane leaflets in a cholesterol dependent manner
    Biochim Biophys Acta, 1858 (2), 281-8
    DOI 10.1016/j.bbamem.2015.12.003, PubMed 26654782
  21. Skotland T, Iversen TG, Torgersen ML, Sandvig K (2015)
    Cell-penetrating peptides: possibilities and challenges for drug delivery in vitro and in vivo
    Molecules, 20 (7), 13313-23
    DOI 10.3390/molecules200713313, PubMed 26205056
  22. Słomińska-Wojewódzka M, Sandvig K (2015)
    The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation
    Molecules, 20 (6), 9816-46
    DOI 10.3390/molecules20069816, PubMed 26023941
  23. Sokołowska I, Piłka ES, Sandvig K, Węgrzyn G, Słomińska-Wojewódzka M (2015)
    Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells
    BMC Cell Biol, 16, 1
    DOI 10.1186/s12860-015-0047-7, PubMed 25655076
  24. Sternemalm J, Geimer S, Frikstad KA, Schink KO, Stokke T, Patzke S (2015)
    CSPP-L Associates with the Desmosome of Polarized Epithelial Cells and Is Required for Normal Spheroid Formation
    PLoS One, 10 (8), e0134789
    DOI 10.1371/journal.pone.0134789, PubMed 26241740
  25. Szalai P, Hagen LK, Sætre F, Luhr M, Sponheim M, Øverbye A, Mills IG, Seglen PO, Engedal N (2015)
    Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs
    Exp Cell Res, 333 (1), 21-38
    DOI 10.1016/j.yexcr.2015.02.003, PubMed 25684710
  26. Theodossiou TA, Wälchli S, Olsen CE, Skarpen E, Berg K (2015)
    Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
    ACS Chem Biol, 11 (1), 251-62
    DOI 10.1021/acschembio.5b00734, PubMed 26569462
  27. Thorvaldsen TE, Pedersen NM, Wenzel EM, Schultz SW, Brech A, Liestøl K, Waaler J, Krauss S, Stenmark H (2015)
    Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes
    Mol Cancer Res, 13 (11), 1487-501
    DOI 10.1158/1541-7786.MCR-15-0125, PubMed 26124443
  28. Vietri M, Schink KO, Campsteijn C, Wegner CS, Schultz SW, Christ L, Thoresen SB, Brech A, Raiborg C, Stenmark H (2015)
    Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing
    Nature, 522 (7555), 231-5
    DOI 10.1038/nature14408, PubMed 26040712
  29. Wendel T, Zhen Y, Suo Z, Bruheim S, Wiedlocha A (2015)
    The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo
    Exp Cell Res, 340 (2), 220-6
    DOI 10.1016/j.yexcr.2015.12.017, PubMed 26748184
  30. Yáñez-Mó M, Siljander PR, Andreu Z, Zavec AB, Borràs FE, Buzas EI, Buzas K, Casal E, Cappello F, Carvalho J, Colás E, Cordeiro-da Silva A, Fais S, Falcon-Perez JM, Ghobrial IM, Giebel B, Gimona M, Graner M, Gursel I, Gursel M, Heegaard NH, Hendrix A, Kierulf P, Kokubun K, Kosanovic M et al. (2015)
    Biological properties of extracellular vesicles and their physiological functions
    J Extracell Vesicles, 4, 27066
    DOI 10.3402/jev.v4.27066, PubMed 25979354
  31. Zhen Y, Stenmark H (2015)
    Cellular functions of Rab GTPases at a glance
    J Cell Sci, 128 (17), 3171-6
    DOI 10.1242/jcs.166074, PubMed 26272922
  32. Øverbye A, Skotland T, Koehler CJ, Thiede B, Seierstad T, Berge V, Sandvig K, Llorente A (2015)
    Identification of prostate cancer biomarkers in urinary exosomes
    Oncotarget, 6 (30), 30357-76
    DOI 10.18632/oncotarget.4851, PubMed 26196085
  33. Øvrebø JI, Campsteijn C, Kourtesis I, Hausen H, Raasholm M, Thompson EM (2015)
    Functional specialization of chordate CDK1 paralogs during oogenic meiosis
    Cell Cycle, 14 (6), 880-93
    DOI 10.1080/15384101.2015.1006000, PubMed 25714331

Publications 2014

  1. Anda S, Boye E, Grallert B (2014)
    Cell-cycle analyses using thymidine analogues in fission yeast
    PLoS One, 9 (2), e88629
    DOI 10.1371/journal.pone.0088629, PubMed 24551125
  2. Asp N, Pust S, Sandvig K (2014)
    Flotillin depletion affects ErbB protein levels in different human breast cancer cells
    Biochim Biophys Acta, 1843 (9), 1987-96
    DOI 10.1016/j.bbamcr.2014.04.013, PubMed 24747692
  3. Bergan J, Skotland T, Lingelem AB, Simm R, Spilsberg B, Lindbäck T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2014)
    The ether lipid precursor hexadecylglycerol protects against Shiga toxins
    Cell Mol Life Sci, 71 (21), 4285-300
    DOI 10.1007/s00018-014-1624-1, PubMed 24740796
  4. Bull-Hansen B, Cao Y, Berg K, Skarpen E, Rosenblum MG, Weyergang A (2014)
    Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome
    J Control Release, 182, 58-66
    DOI 10.1016/j.jconrel.2014.03.014, PubMed 24637464
  5. Cordara G, Winter HC, Goldstein IJ, Krengel U, Sandvig K (2014)
    The fungal chimerolectin MOA inhibits protein and DNA synthesis in NIH/3T3 cells and may induce BAX-mediated apoptosis
    Biochem Biophys Res Commun, 447 (4), 586-9
    DOI 10.1016/j.bbrc.2014.04.043, PubMed 24747075
  6. Danks GB, Raasholm M, Campsteijn C, Long AM, Manak JR, Lenhard B, Thompson EM (2014)
    Trans-splicing and operons in metazoans: translational control in maternally regulated development and recovery from growth arrest
    Mol Biol Evol, 32 (3), 585-99
    DOI 10.1093/molbev/msu336, PubMed 25525214
  7. Demarco RS, Eikenes ÅH, Haglund K, Jones DL (2014)
    Investigating spermatogenesis in Drosophila melanogaster
    Methods, 68 (1), 218-27
    DOI 10.1016/j.ymeth.2014.04.020, PubMed 24798812
  8. Fossum-Raunehaug S, Helgesen E, Stokke C, Skarstad K (2014)
    Escherichia coli SeqA structures relocalize abruptly upon termination of origin sequestration during multifork DNA replication
    PLoS One, 9 (10), e110575
    DOI 10.1371/journal.pone.0110575, PubMed 25333813
  9. Haugsten EM, Brech A, Liestøl K, Norman JC, Wesche J (2014)
    Photoactivation approaches reveal a role for Rab11 in FGFR4 recycling and signalling
    Traffic, 15 (6), 665-83
    DOI 10.1111/tra.12168, PubMed 24589086
  10. Hermansson E, Schultz S, Crowther D, Linse S, Winblad B, Westermark G, Johansson J, Presto J (2014)
    The chaperone domain BRICHOS prevents CNS toxicity of amyloid-β peptide in Drosophila melanogaster
    Dis Model Mech, 7 (6), 659-65
    DOI 10.1242/dmm.014787, PubMed 24682783
  11. Holland P, Torgersen ML, Sandvig K, Simonsen A (2014)
    LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis
    Traffic, 15 (12), 1390-405
    DOI 10.1111/tra.12227, PubMed 25216107
  12. Kvalvaag AS, Pust S, Sandvig K (2014)
    Vps11, a subunit of the tethering complexes HOPS and CORVET, is involved in regulation of glycolipid degradation and retrograde toxin transport
    Commun Integr Biol, 7 (1), e28129
    DOI 10.4161/cib.28129, PubMed 24778763
  13. Lund K, Bostad M, Skarpen E, Braunagel M, Kiprijanov S, Krauss S, Duncan A, Høgset A, Selbo PK (2014)
    The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
    MAbs, 6 (4), 1038-50
    DOI 10.4161/mabs.28207, PubMed 24525727
  14. Morigen M, Flåtten I, Skarstad K (2014)
    The Escherichia coli datA site promotes proper regulation of cell division
    Microbiology (Reading), 160 (Pt 4), 703-710
    DOI 10.1099/mic.0.074898-0, PubMed 24574433
  15. Odsbu I, Skarstad K (2014)
    DNA compaction in the early part of the SOS response is dependent on RecN and RecA
    Microbiology (Reading), 160 (Pt 5), 872-882
    DOI 10.1099/mic.0.075051-0, PubMed 24615185
  16. Oppelt A, Haugsten EM, Zech T, Danielsen HE, Sveen A, Lobert VH, Skotheim RI, Wesche J (2014)
    PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1
    Biochem J, 461 (3), 383-90
    DOI 10.1042/BJ20140132, PubMed 24840251
  17. Palibrk V, Lång E, Lång A, Schink KO, Rowe AD, Bøe SO (2014)
    Promyelocytic leukemia bodies tether to early endosomes during mitosis
    Cell Cycle, 13 (11), 1749-55
    DOI 10.4161/cc.28653, PubMed 24675887
  18. Phuyal S, Hessvik NP, Skotland T, Sandvig K, Llorente A (2014)
    Regulation of exosome release by glycosphingolipids and flotillins
    FEBS J, 281 (9), 2214-27
    DOI 10.1111/febs.12775, PubMed 24605801
  19. Phuyal S, Skotland T, Hessvik NP, Simolin H, Øverbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A (2014)
    The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
    J Biol Chem, 290 (7), 4225-37
    DOI 10.1074/jbc.M114.593962, PubMed 25519911
  20. Raiborg C, Stenmark H (2014)
    An ER clamp for endosome fission
    EMBO J, 34 (2), 136-7
    DOI 10.15252/embj.201490707, PubMed 25502456
  21. Reidick C, El Magraoui F, Meyer HE, Stenmark H, Platta HW (2014)
    Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO
    Cancers (Basel), 7 (1), 1-29
    DOI 10.3390/cancers7010001, PubMed 25545884
  22. Sagona AP, Nezis IP, Stenmark H (2014)
    Association of CHMP4B and autophagy with micronuclei: implications for cataract formation
    Biomed Res Int, 2014, 974393
    DOI 10.1155/2014/974393, PubMed 24741567
  23. Salvi M, Raiborg C, Hanson PI, Campsteijn C, Stenmark H, Pinna LA (2014)
    CK2 involvement in ESCRT-III complex phosphorylation
    Arch Biochem Biophys, 545, 83-91
    DOI 10.1016/j.abb.2014.01.006, PubMed 24440309
  24. Sandvig K, Bergan J, Kavaliauskiene S, Skotland T (2014)
    Lipid requirements for entry of protein toxins into cells
    Prog Lipid Res, 54, 1-13
    DOI 10.1016/j.plipres.2014.01.001, PubMed 24462587
  25. Simm R, Ahmad I, Rhen M, Le Guyon S, Römling U (2014)
    Regulation of biofilm formation in Salmonella enterica serovar Typhimurium
    Future Microbiol, 9 (11), 1261-82
    DOI 10.2217/fmb.14.88, PubMed 25437188
  26. Skotland T, Iversen TG, Sandvig K (2014)
    Development of nanoparticles for clinical use
    Nanomedicine (Lond), 9 (9), 1295-9
    DOI 10.2217/nnm.14.81, PubMed 25204821
  27. Sletten T, Kostas M, Bober J, Sorensen V, Yadollahi M, Olsnes S, Tomala J, Otlewski J, Zakrzewska M, Wiedlocha A (2014)
    Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1)
    PLoS One, 9 (3), e90687
    DOI 10.1371/journal.pone.0090687, PubMed 24595027
  28. Słomińska-Wojewódzka M, Pawlik A, Sokołowska I, Antoniewicz J, Węgrzyn G, Sandvig K (2014)
    The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol
    Biochem J, 457 (3), 485-96
    DOI 10.1042/BJ20130155, PubMed 24200403
  29. Solhaug A, Torgersen ML, Holme JA, Lagadic-Gossmann D, Eriksen GS (2014)
    Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol
    Toxicology, 326, 119-29
    DOI 10.1016/j.tox.2014.10.009, PubMed 25456271
  30. Stiebler AC, Freitag J, Schink KO, Stehlik T, Tillmann BA, Ast J, Bölker M (2014)
    Ribosomal readthrough at a short UGA stop codon context triggers dual localization of metabolic enzymes in Fungi and animals
    PLoS Genet, 10 (10), e1004685
    DOI 10.1371/journal.pgen.1004685, PubMed 25340584
  31. Thoresen SB, Campsteijn C, Vietri M, Schink KO, Liestøl K, Andersen JS, Raiborg C, Stenmark H (2014)
    ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4
    Nat Cell Biol, 16 (6), 550-60
    DOI 10.1038/ncb2959, PubMed 24814515
  32. Wegner CS, Schink KO, Stenmark H, Brech A (2014)
    Monitoring phosphatidylinositol 3-phosphate in multivesicular endosome biogenesis
    Methods Enzymol, 534, 3-23
    DOI 10.1016/B978-0-12-397926-1.00001-9, PubMed 24359945
  33. Yermakova A, Klokk TI, Cole R, Sandvig K, Mantis NJ (2014)
    Antibody-mediated inhibition of ricin toxin retrograde transport
    mBio, 5 (2), e00995
    DOI 10.1128/mBio.00995-13, PubMed 24713323

Publications 2013

  1. Amoasii L, Hnia K, Chicanne G, Brech A, Cowling BS, Müller MM, Schwab Y, Koebel P, Ferry A, Payrastre B, Laporte J (2013)
    Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo
    J Cell Sci, 126 (Pt 8), 1806-19
    DOI 10.1242/jcs.118505, PubMed 23444364
  2. Bergan J, Skotland T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2013)
    The ether lipid precursor hexadecylglycerol causes major changes in the lipidome of HEp-2 cells
    PLoS One, 8 (9), e75904
    DOI 10.1371/journal.pone.0075904, PubMed 24098742
  3. Bostad M, Berg K, Høgset A, Skarpen E, Stenmark H, Selbo PK (2013)
    Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
    J Control Release, 168 (3), 317-26
    DOI 10.1016/j.jconrel.2013.03.023, PubMed 23567040
  4. Eikenes ÅH, Brech A, Stenmark H, Haglund K (2013)
    Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline
    Dev Biol, 377 (1), 9-20
    DOI 10.1016/j.ydbio.2013.02.021, PubMed 23499247
  5. Engedal N, Torgersen ML, Guldvik IJ, Barfeld SJ, Bakula D, Sætre F, Hagen LK, Patterson JB, Proikas-Cezanne T, Seglen PO, Simonsen A, Mills IG (2013)
    Modulation of intracellular calcium homeostasis blocks autophagosome formation
    Autophagy, 9 (10), 1475-90
    DOI 10.4161/auto.25900, PubMed 23970164
  6. Flinder LI, Wierød L, Rosseland CM, Huitfeldt HS, Skarpen E (2013)
    FAK regulates Cdk2 in EGF-stimulated primary cultures of hepatocytes
    J Cell Physiol, 228 (6), 1304-13
    DOI 10.1002/jcp.24287, PubMed 23168795
  7. Flåtten I, Skarstad K (2013)
    The Fis protein has a stimulating role in initiation of replication in Escherichia coli in vivo
    PLoS One, 8 (12), e83562
    DOI 10.1371/journal.pone.0083562, PubMed 24358293
  8. Grallert B, Boye E (2013)
    GCN2, an old dog with new tricks
    Biochem Soc Trans, 41 (6), 1687-91
    DOI 10.1042/BST20130210, PubMed 24256275
  9. Gregers TF, Skånland SS, Wälchli S, Bakke O, Sandvig K (2013)
    BiP negatively affects ricin transport
    Toxins (Basel), 5 (5), 969-82
    DOI 10.3390/toxins5050969, PubMed 23666197
  10. Haugsten EM, Oppelt A, Wesche J (2013)
    Phosphatidylinositol 5-phosphate is a second messenger important for cell migration
    Commun Integr Biol, 6 (5), e25446
    DOI 10.4161/cib.25446, PubMed 24265857
  11. Henne WM, Stenmark H, Emr SD (2013)
    Molecular mechanisms of the membrane sculpting ESCRT pathway
    Cold Spring Harb Perspect Biol, 5 (9)
    DOI 10.1101/cshperspect.a016766, PubMed 24003212
  12. Hessvik NP, Sandvig K, Llorente A (2013)
    Exosomal miRNAs as Biomarkers for Prostate Cancer
    Front Genet, 4, 36
    DOI 10.3389/fgene.2013.00036, PubMed 23519132
  13. Isakson P, Lystad AH, Breen K, Koster G, Stenmark H, Simonsen A (2013)
    TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
    Autophagy, 9 (12), 1955-64
    DOI 10.4161/auto.26085, PubMed 24128730
  14. Kavaliauskiene S, Nymark CM, Bergan J, Simm R, Sylvänne T, Simolin H, Ekroos K, Skotland T, Sandvig K (2013)
    Cell density-induced changes in lipid composition and intracellular trafficking
    Cell Mol Life Sci, 71 (6), 1097-116
    DOI 10.1007/s00018-013-1441-y, PubMed 23921715
  15. Knævelsrud H, Søreng K, Raiborg C, Håberg K, Rasmuson F, Brech A, Liestøl K, Rusten TE, Stenmark H, Neufeld TP, Carlsson SR, Simonsen A (2013)
    Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation
    J Cell Biol, 202 (2), 331-49
    DOI 10.1083/jcb.201205129, PubMed 23878278
  16. Kvalvaag AS, Pust S, Sundet KI, Engedal N, Simm R, Sandvig K (2013)
    The ERM proteins ezrin and moesin regulate retrograde Shiga toxin transport
    Traffic, 14 (7), 839-52
    DOI 10.1111/tra.12077, PubMed 23593995
  17. Llorente A, Skotland T, Sylvänne T, Kauhanen D, Róg T, Orłowski A, Vattulainen I, Ekroos K, Sandvig K (2013)
    Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
    Biochim Biophys Acta, 1831 (7), 1302-9
    DOI 10.1016/j.bbalip.2013.04.011, PubMed 24046871
  18. Lueke K, Kaiser T, Svetlitchny A, Welzel O, Wenzel EM, Tyagarajan S, Kornhuber J, Groemer TW (2013)
    Basic presynaptic functions in hippocampal neurons are not affected by acute or chronic lithium treatment
    J Neural Transm (Vienna), 121 (2), 211-9
    DOI 10.1007/s00702-013-1087-9, PubMed 24036894
  19. Nadratowska-Wesolowska B, Haugsten EM, Zakrzewska M, Jakimowicz P, Zhen Y, Pajdzik D, Wesche J, Wiedlocha A (2013)
    RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789
    Oncogene, 33 (40), 4823-36
    DOI 10.1038/onc.2013.425, PubMed 24141780
  20. O Farrell F, Rusten TE, Stenmark H (2013)
    Phosphoinositide 3-kinases as accelerators and brakes of autophagy
    FEBS J, 280 (24), 6322-37
    DOI 10.1111/febs.12486, PubMed 23953235
  21. O'Farrell F, Wang S, Katheder N, Rusten TE, Samakovlis C (2013)
    Two-tiered control of epithelial growth and autophagy by the insulin receptor and the ret-like receptor, stitcher
    PLoS Biol, 11 (7), e1001612
    DOI 10.1371/journal.pbio.1001612, PubMed 23935447
  22. Raiborg C, Schink KO, Stenmark H (2013)
    Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic
    FEBS J, 280 (12), 2730-42
    DOI 10.1111/febs.12116, PubMed 23289851
  23. Rødland GE, Tvegård T, Boye E, Grallert B (2013)
    Crosstalk between the Tor and Gcn2 pathways in response to different stresses
    Cell Cycle, 13 (3), 453-61
    DOI 10.4161/cc.27270, PubMed 24280780
  24. Sandvig K, Skotland T, van Deurs B, Klokk TI (2013)
    Retrograde transport of protein toxins through the Golgi apparatus
    Histochem Cell Biol, 140 (3), 317-26
    DOI 10.1007/s00418-013-1111-z, PubMed 23765164
  25. Schink KO, Raiborg C, Stenmark H (2013)
    Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling
    Bioessays, 35 (10), 900-12
    DOI 10.1002/bies.201300064, PubMed 23881848
  26. Schneikert J, Vijaya Chandra SH, Ruppert JG, Ray S, Wenzel EM, Behrens J (2013)
    Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation
    PLoS One, 8 (7), e68072
    DOI 10.1371/journal.pone.0068072, PubMed 23840886
  27. Shahzidi S, Brech A, Sioud M, Li X, Suo Z, Nesland JM, Peng Q (2013)
    Lamin A/C cleavage by caspase-6 activation is crucial for apoptotic induction by photodynamic therapy with hexaminolevulinate in human B-cell lymphoma cells
    Cancer Lett, 339 (1), 25-32
    DOI 10.1016/j.canlet.2013.07.026, PubMed 23916608
  28. Skarstad K, Katayama T (2013)
    Regulating DNA replication in bacteria
    Cold Spring Harb Perspect Biol, 5 (4), a012922
    DOI 10.1101/cshperspect.a012922, PubMed 23471435
  29. Slominska-Wojewodzka M, Sandvig K (2013)
    Ricin and Ricin-Containing Immunotoxins: Insights into Intracellular Transport and Mechanism of action in Vitro
    Antibodies, 2 (2), 236-269
    DOI 10.3390/antib2020236
  30. Solhaug A, Holme JA, Haglund K, Dendele B, Sergent O, Pestka J, Lagadic-Gossmann D, Eriksen GS (2013)
    Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages
    Toxicol Lett, 219 (1), 8-17
    DOI 10.1016/j.toxlet.2013.02.012, PubMed 23454835
  31. Stratford EW, Bostad M, Castro R, Skarpen E, Berg K, Høgset A, Myklebost O, Selbo PK (2013)
    Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity
    Biochim Biophys Acta, 1830 (8), 4235-43
    DOI 10.1016/j.bbagen.2013.04.033, PubMed 23643966
  32. Vörös A, Simm R, Kroeger JK, Kolstø AB (2013)
    Gene transcription from the linear plasmid pBClin15 leads to cell lysis and extracellular DNA-dependent aggregation of Bacillus cereus ATCC 14579 in response to quinolone-induced stress
    Microbiology (Reading), 159 (Pt 11), 2283-2293
    DOI 10.1099/mic.0.069674-0, PubMed 24002748
  33. Weel-Sneve R, Kristiansen KI, Odsbu I, Dalhus B, Booth J, Rognes T, Skarstad K, Bjørås M (2013)
    Single transmembrane peptide DinQ modulates membrane-dependent activities
    PLoS Genet, 9 (2), e1003260
    DOI 10.1371/journal.pgen.1003260, PubMed 23408903
  34. Wu X, Chen JY, Brech A, Fang C, Wang J, Helm PJ, Peng Q (2013)
    The use of femto-second lasers to trigger powerful explosions of gold nanorods to destroy cancer cells
    Biomaterials, 34 (26), 6157-62
    DOI 10.1016/j.biomaterials.2013.04.048, PubMed 23706782
  35. Zakrzewska M, Haugsten EM, Nadratowska-Wesolowska B, Oppelt A, Hausott B, Jin Y, Otlewski J, Wesche J, Wiedlocha A (2013)
    ERK-mediated phosphorylation of fibroblast growth factor receptor 1 on Ser777 inhibits signaling
    Sci Signal, 6 (262), ra11
    DOI 10.1126/scisignal.2003087, PubMed 23405013

Publications 2012

  1. Abrahamsen H, Stenmark H, Platta HW (2012)
    Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression
    FEBS Lett, 586 (11), 1584-91
    DOI 10.1016/j.febslet.2012.04.046, PubMed 22673570
  2. Becker GL, Lu Y, Hardes K, Strehlow B, Levesque C, Lindberg I, Sandvig K, Bakowsky U, Day R, Garten W, Steinmetzer T (2012)
    Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases
    J Biol Chem, 287 (26), 21992-2003
    DOI 10.1074/jbc.M111.332643, PubMed 22539349
  3. Bergan J, Dyve Lingelem AB, Simm R, Skotland T, Sandvig K (2012)
    Shiga toxins
    Toxicon, 60 (6), 1085-107
    DOI 10.1016/j.toxicon.2012.07.016, PubMed 22960449
  4. Bøe CA, Knutsen JH, Boye E, Grallert B (2012)
    Hpz1 modulates the G1-S transition in fission yeast
    PLoS One, 7 (9), e44539
    DOI 10.1371/journal.pone.0044539, PubMed 22970243
  5. Bøe CA, Krohn M, Rødland GE, Capiaghi C, Maillard O, Thoma F, Boye E, Grallert B (2012)
    Induction of a G1-S checkpoint in fission yeast
    Proc Natl Acad Sci U S A, 109 (25), 9911-6
    DOI 10.1073/pnas.1204901109, PubMed 22665798
  6. Danks G, Campsteijn C, Parida M, Butcher S, Doddapaneni H, Fu B, Petrin R, Metpally R, Lenhard B, Wincker P, Chourrout D, Thompson EM, Manak JR (2012)
    OikoBase: a genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica
    Nucleic Acids Res, 41 (Database issue), D845-53
    DOI 10.1093/nar/gks1159, PubMed 23185044
  7. Fingland N, Flåtten I, Downey CD, Fossum-Raunehaug S, Skarstad K, Crooke E (2012)
    Depletion of acidic phospholipids influences chromosomal replication in Escherichia coli
    Microbiologyopen, 1 (4), 450-66
    DOI 10.1002/mbo3.46, PubMed 23233230
  8. Haglund K, Dikic I (2012)
    The role of ubiquitylation in receptor endocytosis and endosomal sorting
    J Cell Sci, 125 (Pt 2), 265-75
    DOI 10.1242/jcs.091280, PubMed 22357968
  9. Hessvik NP, Phuyal S, Brech A, Sandvig K, Llorente A (2012)
    Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells
    Biochim Biophys Acta, 1819 (11-12), 1154-63
    DOI 10.1016/j.bbagrm.2012.08.016, PubMed 22982408
  10. Huotari J, Meyer-Schaller N, Hubner M, Stauffer S, Katheder N, Horvath P, Mancini R, Helenius A, Peter M (2012)
    Cullin-3 regulates late endosome maturation
    Proc Natl Acad Sci U S A, 109 (3), 823-8
    DOI 10.1073/pnas.1118744109, PubMed 22219362
  11. Ilina P, Hyvonen Z, Saura M, Sandvig K, Yliperttula M, Ruponen M (2012)
    Genetic blockage of endocytic pathways reveals differences in the intracellular processing of non-viral gene delivery systems
    J Control Release, 163 (3), 385-95
    DOI 10.1016/j.jconrel.2012.09.016, PubMed 23041276
  12. Iversen TG, Frerker N, Sandvig K (2012)
    Uptake of ricinB-quantum dot nanoparticles by a macropinocytosis-like mechanism
    J Nanobiotechnology, 10, 33
    DOI 10.1186/1477-3155-10-33, PubMed 22849338
  13. Jha AN, Singh VK, Kumari N, Singh A, Antony J, van Tong H, Singh S, Pati SS, Patra PK, Singh R, Toan NL, Song le H, Assaf A, Messias-Reason IJ, Velavan TP, Singh L, Thangaraj K (2012)
    IL-4 haplotype -590T, -34T and intron-3 VNTR R2 is associated with reduced malaria risk among ancestral indian tribal populations
    PLoS One, 7 (10), e48136
    DOI 10.1371/journal.pone.0048136, PubMed 23110190
  14. Kalra H, Simpson RJ, Ji H, Aikawa E, Altevogt P, Askenase P, Bond VC, Borràs FE, Breakefield X, Budnik V, Buzas E, Camussi G, Clayton A, Cocucci E, Falcon-Perez JM, Gabrielsson S, Gho YS, Gupta D, Harsha HC, Hendrix A, Hill AF, Inal JM, Jenster G, Krämer-Albers EM, Lim SK et al. (2012)
    Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
    PLoS Biol, 10 (12), e1001450
    DOI 10.1371/journal.pbio.1001450, PubMed 23271954
  15. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A et al. (2012)
    Guidelines for the use and interpretation of assays for monitoring autophagy
    Autophagy, 8 (4), 445-544
    DOI 10.4161/auto.19496, PubMed 22966490
  16. Lobert VH, Bruun J, Abrahamsen H, Lothe RA, Stenmark H, Kolberg M, Campsteijn C (2012)
    Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin
    EMBO Rep, 14 (1), 10-1
    DOI 10.1038/embor.2012.188, PubMed 23229585
  17. Lobert VH, Stenmark H (2012)
    The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain
    J Cell Sci, 125 (Pt 1), 29-36
    DOI 10.1242/jcs.088310, PubMed 22266905
  18. Nezis IP (2012)
    Selective autophagy in Drosophila
    Int J Cell Biol, 2012, 146767
    DOI 10.1155/2012/146767, PubMed 22567011
  19. Nezis IP, Stenmark H (2012)
    p62 at the interface of autophagy, oxidative stress signaling, and cancer
    Antioxid Redox Signal, 17 (5), 786-93
    DOI 10.1089/ars.2011.4394, PubMed 22074114
  20. Oksvold MP, Pedersen NM, Forfang L, Smeland EB (2012)
    Effect of cycloheximide on epidermal growth factor receptor trafficking and signaling
    FEBS Lett, 586 (20), 3575-81
    DOI 10.1016/j.febslet.2012.08.022, PubMed 22971756
  21. Oppelt A, Lobert VH, Haglund K, Mackey AM, Rameh LE, Liestøl K, Schink KO, Pedersen NM, Wenzel EM, Haugsten EM, Brech A, Rusten TE, Stenmark H, Wesche J (2012)
    Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration
    EMBO Rep, 14 (1), 57-64
    DOI 10.1038/embor.2012.183, PubMed 23154468
  22. Pedersen NM, Raiborg C, Brech A, Skarpen E, Roxrud I, Platta HW, Liestøl K, Stenmark H (2012)
    The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion
    Traffic, 13 (11), 1547-63
    DOI 10.1111/j.1600-0854.2012.01400.x, PubMed 22816767
  23. Platta HW, Abrahamsen H, Thoresen SB, Stenmark H (2012)
    Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1
    Biochem J, 441 (1), 399-406
    DOI 10.1042/BJ20111424, PubMed 21936852
  24. Pust S, Klokk TI, Musa N, Jenstad M, Risberg B, Erikstein B, Tcatchoff L, Liestøl K, Danielsen HE, van Deurs B, Sandvig K (2012)
    Flotillins as regulators of ErbB2 levels in breast cancer
    Oncogene, 32 (29), 3443-51
    DOI 10.1038/onc.2012.357, PubMed 22869152
  25. Sak MM, Breen K, Rønning SB, Pedersen NM, Bertelsen V, Stang E, Madshus IH (2012)
    The oncoprotein ErbB3 is endocytosed in the absence of added ligand in a clathrin-dependent manner
    Carcinogenesis, 33 (5), 1031-9
    DOI 10.1093/carcin/bgs128, PubMed 22436610
  26. Sandvig K, Llorente A (2012)
    Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3
    Mol Cell Proteomics, 11 (7), M111.012914
    DOI 10.1074/mcp.M111.012914, PubMed 22457534
  27. Skotland T (2012)
    Molecular imaging: challenges of bringing imaging of intracellular targets into common clinical use
    Contrast Media Mol Imaging, 7 (1), 1-6
    DOI 10.1002/cmmi.458, PubMed 22344874
  28. Stenmark H (2012)
    The Rabs: a family at the root of metazoan evolution
    BMC Biol, 10, 68
    DOI 10.1186/1741-7007-10-68, PubMed 22873178
  29. Stokke C, Flåtten I, Skarstad K (2012)
    An easy-to-use simulation program demonstrates variations in bacterial cell cycle parameters depending on medium and temperature
    PLoS One, 7 (2), e30981
    DOI 10.1371/journal.pone.0030981, PubMed 22348034
  30. Stratford EW, Castro R, Daffinrud J, Skårn M, Lauvrak S, Munthe E, Myklebost O (2012)
    Characterization of liposarcoma cell lines for preclinical and biological studies
    Sarcoma, 2012, 148614
    DOI 10.1155/2012/148614, PubMed 22911243
  31. Szlachcic A, Pala K, Zakrzewska M, Jakimowicz P, Wiedlocha A, Otlewski J (2012)
    FGF1-gold nanoparticle conjugates targeting FGFR efficiently decrease cell viability upon NIR irradiation
    Int J Nanomedicine, 7, 5915-27
    DOI 10.2147/IJN.S36575, PubMed 23226697
  32. Tabassum R, Chauhan G, Dwivedi OP, Mahajan A, Jaiswal A, Kaur I, Bandesh K, Singh T, Mathai BJ, Pandey Y, Chidambaram M, Sharma A, Chavali S, Sengupta S, Ramakrishnan L, Venkatesh P, Aggarwal SK, Ghosh S, Prabhakaran D, Srinath RK, Saxena M, Banerjee M, Mathur S, Bhansali A, Shah VN et al. (2012)
    Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21
    Diabetes, 62 (3), 977-86
    DOI 10.2337/db12-0406, PubMed 23209189
  33. Tcatchoff L, Andersson S, Utskarpen A, Klokk TI, Skånland SS, Pust S, Gerke V, Sandvig K (2012)
    Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin
    PLoS One, 7 (7), e40429
    DOI 10.1371/journal.pone.0040429, PubMed 22792315
  34. Waldminghaus T, Weigel C, Skarstad K (2012)
    Replication fork movement and methylation govern SeqA binding to the Escherichia coli chromosome
    Nucleic Acids Res, 40 (12), 5465-76
    DOI 10.1093/nar/gks187, PubMed 22373925
  35. Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S (2012)
    A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice
    Cancer Res, 72 (11), 2822-32
    DOI 10.1158/0008-5472.CAN-11-3336, PubMed 22440753
  36. Zhen Y, Sørensen V, Skjerpen CS, Haugsten EM, Jin Y, Wälchli S, Olsnes S, Wiedlocha A (2012)
    Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnα1 and Kpnβ1
    Traffic, 13 (5), 650-64
    DOI 10.1111/j.1600-0854.2012.01341.x, PubMed 22321063
  37. Østerud B, Skotland T (2012)
    Doping analyses are not on safe ground
    Tidsskr Nor Laegeforen, 132 (8), 929-30
    DOI 10.4045/tidsskr.12.0252, PubMed 22562317

Publications 2011

  1. Abrahamsen H, Stenmark H (2011)
    Cell biology. Growth signaling from inside
    Science, 334 (6056), 611-2
    DOI 10.1126/science.1214355, PubMed 22053037
  2. Bartlett BJ, Isakson P, Lewerenz J, Sanchez H, Kotzebue RW, Cumming RC, Harris GL, Nezis IP, Schubert DR, Simonsen A, Finley KD (2011)
    p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects
    Autophagy, 7 (6), 572-83
    DOI 10.4161/auto.7.6.14943, PubMed 21325881
  3. Cordara G, Egge-Jacobsen W, Johansen HT, Winter HC, Goldstein IJ, Sandvig K, Krengel U (2011)
    Marasmius oreades agglutinin (MOA) is a chimerolectin with proteolytic activity
    Biochem Biophys Res Commun, 408 (3), 405-10
    DOI 10.1016/j.bbrc.2011.04.031, PubMed 21513701
  4. Dang H, Klokk TI, Schaheen B, McLaughlin BM, Thomas AJ, Durns TA, Bitler BG, Sandvig K, Fares H (2011)
    Derlin-dependent retrograde transport from endosomes to the Golgi apparatus
    Traffic, 12 (10), 1417-31
    DOI 10.1111/j.1600-0854.2011.01243.x, PubMed 21722281
  5. Dyve Lingelem AB, Bergan J, Sandvig K (2011)
    Inhibitors of intravesicular acidification protect against Shiga toxin in a pH-independent manner
    Traffic, 13 (3), 443-54
    DOI 10.1111/j.1600-0854.2011.01319.x, PubMed 22132807
  6. Engedal N, Skotland T, Torgersen ML, Sandvig K (2011)
    Shiga toxin and its use in targeted cancer therapy and imaging
    Microb Biotechnol, 4 (1), 32-46
    DOI 10.1111/j.1751-7915.2010.00180.x, PubMed 21255370
  7. Eskelinen EL, Reggiori F, Baba M, Kovács AL, Seglen PO (2011)
    Seeing is believing: the impact of electron microscopy on autophagy research
    Autophagy, 7 (9), 935-56
    DOI 10.4161/auto.7.9.15760, PubMed 21566462
  8. Freitag J, Lanver D, Böhmer C, Schink KO, Bölker M, Sandrock B (2011)
    Septation of infectious hyphae is critical for appressoria formation and virulence in the smut fungus Ustilago maydis
    PLoS Pathog, 7 (5), e1002044
    DOI 10.1371/journal.ppat.1002044, PubMed 21625538
  9. George A, Panda S, Kudmulwar D, Chhatbar SP, Nayak SC, Krishnan HH (2011)
    Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation
    J Biol Chem, 287 (7), 5042-58
    DOI 10.1074/jbc.M111.308916, PubMed 22184107
  10. Grimm I, Saffian D, Platta HW, Erdmann R (2011)
    The AAA-type ATPases Pex1p and Pex6p and their role in peroxisomal matrix protein import in Saccharomyces cerevisiae
    Biochim Biophys Acta, 1823 (1), 150-8
    DOI 10.1016/j.bbamcr.2011.09.005, PubMed 21963882
  11. Grunau S, Lay D, Mindthoff S, Platta HW, Girzalsky W, Just WW, Erdmann R (2011)
    The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae
    Biochem J, 434 (1), 161-70
    DOI 10.1042/BJ20101115, PubMed 21121900
  12. Haglund K, Nezis IP, Stenmark H (2011)
    Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
    Commun Integr Biol, 4 (1), 1-9
    DOI 10.4161/cib.4.1.13550, PubMed 21509167
  13. Haugsten EM, Zakrzewska M, Brech A, Pust S, Olsnes S, Sandvig K, Wesche J (2011)
    Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling
    PLoS One, 6 (7), e21708
    DOI 10.1371/journal.pone.0021708, PubMed 21779335
  14. Hausott B, Vallant N, Hochfilzer M, Mangger S, Irschick R, Haugsten EM, Klimaschewski L (2011)
    Leupeptin enhances cell surface localization of fibroblast growth factor receptor 1 in adult sensory neurons by increased recycling
    Eur J Cell Biol, 91 (2), 129-38
    DOI 10.1016/j.ejcb.2011.09.009, PubMed 22169219
  15. Helmrich U, Marsano A, Melly L, Wolff T, Christ L, Heberer M, Scherberich A, Martin I, Banfi A (2011)
    Generation of human adult mesenchymal stromal/stem cells expressing defined xenogenic vascular endothelial growth factor levels by optimized transduction and flow cytometry purification
    Tissue Eng Part C Methods, 18 (4), 283-92
    DOI 10.1089/ten.TEC.2011.0413, PubMed 22070632
  16. Hurley JH, Stenmark H (2011)
    Molecular mechanisms of ubiquitin-dependent membrane traffic
    Annu Rev Biophys, 40, 119-42
    DOI 10.1146/annurev-biophys-042910-155404, PubMed 21332354
  17. Iversen TG (2011)
    Nanoparticles hinder intracellular transport
    Trac-Trends Anal. Chem., 30 (10), VII-VIII
  18. Iversen TG, Skotland T, Sandvig K (2011)
    Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies
    Nano Today, 6 (2), 176-185
    DOI 10.1016/j.nantod.2011.02.003
  19. Jin Y, Zhen Y, Haugsten EM, Wiedlocha A (2011)
    The driver of malignancy in KG-1a leukemic cells, FGFR1OP2-FGFR1, encodes an HSP90 addicted oncoprotein
    Cell Signal, 23 (11), 1758-66
    DOI 10.1016/j.cellsig.2011.06.010, PubMed 21745565
  20. Johnsen E, Wilson SR, Odsbu I, Krapp A, Malerod H, Skarstad K, Lundanes E (2011)
    Hydrophilic interaction chromatography of nucleoside triphosphates with temperature as a separation parameter
    J Chromatogr A, 1218 (35), 5981-6
    DOI 10.1016/j.chroma.2011.01.066, PubMed 21315360
  21. Klokk TI, Lingelem AB, Myrann AG, Sandvig K (2011)
    Role of phospholipase A(2) in retrograde transport of ricin
    Toxins (Basel), 3 (9), 1203-19
    DOI 10.3390/toxins3091203, PubMed 22069763
  22. Knutsen JH, Rein ID, Rothe C, Stokke T, Grallert B, Boye E (2011)
    Cell-cycle analysis of fission yeast cells by flow cytometry
    PLoS One, 6 (2), e17175
    DOI 10.1371/journal.pone.0017175, PubMed 21386895
  23. Lind GE, Raiborg C, Danielsen SA, Rognum TO, Thiis-Evensen E, Hoff G, Nesbakken A, Stenmark H, Lothe RA (2011)
    SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
    Oncogene, 30 (37), 3967-78
    DOI 10.1038/onc.2011.109, PubMed 21499309
  24. Lobert VH, Stenmark H (2011)
    Cell polarity and migration: emerging role for the endosomal sorting machinery
    Physiology (Bethesda), 26 (3), 171-80
    DOI 10.1152/physiol.00054.2010, PubMed 21670163
  25. Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
    Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
    Traffic, 12 (9), 1211-26
    DOI 10.1111/j.1600-0854.2011.01220.x, PubMed 21564451
  26. Martinez AL, Roxrud I (2011)
    Basic and discovery-based translational research on cancer was on the agenda at the 21st Congress of the European Association for Cancer Research (EACR) in Oslo, Norway, 26-29 June 2010
    Clin. Transl. Oncol., 13 (1), 1-2
    DOI 10.1007/s12094-011-0608-y
  27. Moosmann A, Campsteijn C, Jansen PW, Nasrallah C, Raasholm M, Stunnenberg HG, Thompson EM (2011)
    Histone variant innovation in a rapidly evolving chordate lineage
    BMC Evol Biol, 11, 208
    DOI 10.1186/1471-2148-11-208, PubMed 21756361
  28. Platta HW, Stenmark H (2011)
    Endocytosis and signaling
    Curr Opin Cell Biol, 23 (4), 393-403
    DOI 10.1016/j.ceb.2011.03.008, PubMed 21474295
  29. Raiborg C, Stenmark H (2011)
    Cell biology. A helix for the final cut
    Science, 331 (6024), 1533-4
    DOI 10.1126/science.1204208, PubMed 21436431
  30. Rusten TE, Vaccari T, Stenmark H (2011)
    Shaping development with ESCRTs
    Nat Cell Biol, 14 (1), 38-45
    DOI 10.1038/ncb2381, PubMed 22193162
  31. Rønning SB, Pedersen NM, Madshus IH, Stang E (2011)
    CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor
    Exp Cell Res, 317 (13), 1804-16
    DOI 10.1016/j.yexcr.2011.05.016, PubMed 21635887
  32. Sagona AP, Nezis IP, Bache KG, Haglund K, Bakken AC, Skotheim RI, Stenmark H (2011)
    A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
    PLoS One, 6 (3), e17086
    DOI 10.1371/journal.pone.0017086, PubMed 21455500
  33. Sandvig K, Pust S, Skotland T, van Deurs B (2011)
    Clathrin-independent endocytosis: mechanisms and function
    Curr Opin Cell Biol, 23 (4), 413-20
    DOI 10.1016/j.ceb.2011.03.007, PubMed 21466956
  34. Schink KO, Stenmark H (2011)
    Cell differentiation: midbody remnants - junk or fate factors?
    Curr Biol, 21 (23), R958-60
    DOI 10.1016/j.cub.2011.10.035, PubMed 22153165
  35. Shahzidi S, Cunderlíková B, Więdłocha A, Zhen Y, Vasovič V, Nesland JM, Peng Q (2011)
    Simultaneously targeting mitochondria and endoplasmic reticulum by photodynamic therapy induces apoptosis in human lymphoma cells
    Photochem Photobiol Sci, 10 (11), 1773-82
    DOI 10.1039/c1pp05169e, PubMed 21881674
  36. Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E (2011)
    Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
    Int J Cancer, 131 (3), 570-81
    DOI 10.1002/ijc.26392, PubMed 21866551
  37. Skotland T, Iversen TG, Sandvig K (2011)
    Comment on "short ligands affect modes of QD uptake and elimination in human cells"
    ACS Nano, 5 (10), 7690; author reply 7691-2
    DOI 10.1021/nn2021953, PubMed 22023400
  38. Sokołowska I, Wälchli S, Węgrzyn G, Sandvig K, Słomińska-Wojewódzka M (2011)
    A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation
    Biochem J, 436 (2), 371-85
    DOI 10.1042/BJ20101493, PubMed 21388347
  39. Stenmark H (2011)
    Harald Stenmark: hands on FYVE-fingers. Interview by Caitlin Sedwick
    J Cell Biol, 192 (4), 544-5
    DOI 10.1083/jcb.1924pi, PubMed 21339328
  40. Stratford EW, Castro R, Wennerstrom A, Holm R, Munthe E, Lauvrak S, Bjerkehagen B, Myklebost O (2011)
    Liposarcoma Cells with Aldefluor and CD133 Activity have a Cancer Stem Cell Potential
    Clin Sarcoma Res, 1 (1), 8
    DOI 10.1186/2045-3329-1-8, PubMed 22612877
  41. Takahashi Y, Shimokawa N, Esmaeili-Mahani S, Morita A, Masuda H, Iwasaki T, Tamura J, Haglund K, Koibuchi N (2011)
    Ligand-induced downregulation of TrkA is partly regulated through ubiquitination by Cbl
    FEBS Lett, 585 (12), 1741-7
    DOI 10.1016/j.febslet.2011.04.056, PubMed 21570973
  42. Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2011)
    Protein C mutation (A267T) results in ER retention and unfolded protein response activation
    PLoS One, 6 (8), e24009
    DOI 10.1371/journal.pone.0024009, PubMed 21901152
  43. Ugland H, Naderi S, Brech A, Collas P, Blomhoff HK (2011)
    cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1
    Autophagy, 7 (10), 1199-211
    DOI 10.4161/auto.7.10.16649, PubMed 21750416
  44. Warsame AA, Aasheim HC, Nustad K, Trøen G, Tierens A, Wang V, Randen U, Dong HP, Heim S, Brech A, Delabie J (2011)
    Splenic marginal zone lymphoma with VH1-02 gene rearrangement expresses poly- and self-reactive antibodies with similar reactivity
    Blood, 118 (12), 3331-9
    DOI 10.1182/blood-2011-03-341651, PubMed 21725051
  45. Wegner CS, Rodahl LM, Stenmark H (2011)
    ESCRT proteins and cell signalling
    Traffic, 12 (10), 1291-7
    DOI 10.1111/j.1600-0854.2011.01210.x, PubMed 21518165
  46. Wesche J, Haglund K, Haugsten EM (2011)
    Fibroblast growth factors and their receptors in cancer
    Biochem J, 437 (2), 199-213
    DOI 10.1042/BJ20101603, PubMed 21711248
  47. Zakrzewska M, Sørensen V, Jin Y, Wiedlocha A, Olsnes S (2011)
    Translocation of exogenous FGF1 into cytosol and nucleus is a periodic event independent of receptor kinase activity
    Exp Cell Res, 317 (7), 1005-15
    DOI 10.1016/j.yexcr.2011.01.003, PubMed 21223966
  48. Øverbye A, Sætre F, Hagen LK, Johansen HT, Seglen PO (2011)
    Autophagic activity measured in whole rat hepatocytes as the accumulation of a novel BHMT fragment (p10), generated in amphisomes by the asparaginyl proteinase, legumain
    Autophagy, 7 (9), 1011-27
    DOI 10.4161/auto.7.9.16436, PubMed 21610319

Publications 2010

  1. Abrahamsen H, Stenmark H (2010)
    Protein secretion: unconventional exit by exophagy
    Curr Biol, 20 (9), R415-8
    DOI 10.1016/j.cub.2010.03.011, PubMed 20462486
  2. Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T (2010)
    p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
    Autophagy, 6 (3), 330-44
    DOI 10.4161/auto.6.3.11226, PubMed 20168092
  3. Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A (2010)
    The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
    Mol Cell, 38 (2), 265-79
    DOI 10.1016/j.molcel.2010.04.007, PubMed 20417604
  4. Groves B, Abrahamsen H, Clingan H, Frantz M, Mavor L, Bailey J, Ma D (2010)
    An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy
    PLoS One, 5 (1), e8877
    DOI 10.1371/journal.pone.0008877, PubMed 20126274
  5. Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestøl K, Dikic I, Palmer R, Stenmark H (2010)
    Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
    Curr Biol, 20 (10), 944-50
    DOI 10.1016/j.cub.2010.03.068, PubMed 20451383
  6. Halaas O, Steigedal M, Haug M, Awuh JA, Ryan L, Brech A, Sato S, Husebye H, Cangelosi GA, Akira S, Strong RK, Espevik T, Flo TH (2010)
    Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathway
    J Infect Dis, 201 (5), 783-92
    DOI 10.1086/650493, PubMed 20121435
  7. Haugsten EM, Wiedlocha A, Olsnes S, Wesche J (2010)
    Roles of fibroblast growth factor receptors in carcinogenesis
    Mol Cancer Res, 8 (11), 1439-52
    DOI 10.1158/1541-7786.MCR-10-0168, PubMed 21047773
  8. Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, Nilsen NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T (2010)
    The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
    Immunity, 33 (4), 583-96
    DOI 10.1016/j.immuni.2010.09.010, PubMed 20933442
  9. Johnsen L, Flåtten I, Morigen, Dalhus B, Bjørås M, Waldminghaus T, Skarstad K (2010)
    The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication
    Mol Microbiol, 79 (2), 433-46
    DOI 10.1111/j.1365-2958.2010.07453.x, PubMed 21219462
  10. Johnsen L, Weigel C, von Kries J, Møller M, Skarstad K (2010)
    A novel DNA gyrase inhibitor rescues Escherichia coli dnaAcos mutant cells from lethal hyperinitiation
    J Antimicrob Chemother, 65 (5), 924-30
    DOI 10.1093/jac/dkq071, PubMed 20228083
  11. Klionsky DJ, Seglen PO (2010)
    The Norse god of autophagy. Interviewed by Daniel J Klionsky
    Autophagy, 6 (8), 1017-31
    DOI 10.4161/auto.6.8.13092, PubMed 20814236
  12. Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
    UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
    Autophagy, 6 (7), 863-70
    DOI 10.4161/auto.6.7.13033, PubMed 20724836
  13. Landsverk OJ, Barois N, Gregers TF, Bakke O (2010)
    Invariant chain increases the half-life of MHC II by delaying endosomal maturation
    Immunol Cell Biol, 89 (5), 619-29
    DOI 10.1038/icb.2010.143, PubMed 21116285
  14. Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L, Stenmark H (2010)
    Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes
    Dev Cell, 19 (1), 148-59
    DOI 10.1016/j.devcel.2010.06.010, PubMed 20643357
  15. Lobert VH, Stenmark H (2010)
    Ubiquitination of α-integrin cytoplasmic tails
    Commun Integr Biol, 3 (6), 583-5
    DOI 10.4161/cib.3.6.13176, PubMed 21331246
  16. Malagoli D, Abdalla FC, Cao Y, Feng Q, Fujisaki K, Gregorc A, Matsuo T, Nezis IP, Papassideri IS, Sass M, Silva-Zacarin EC, Tettamanti G, Umemiya-Shirafuji R (2010)
    Autophagy and its physiological relevance in arthropods: current knowledge and perspectives
    Autophagy, 6 (5), 575-88
    DOI 10.4161/auto.6.5.11962, PubMed 20458176
  17. Nezis IP, Sagona AP, Schink KO, Stenmark H (2010)
    Divide and ProsPer: the emerging role of PtdIns3P in cytokinesis
    Trends Cell Biol, 20 (11), 642-9
    DOI 10.1016/j.tcb.2010.08.010, PubMed 20880709
  18. Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
    Autophagy as a trigger for cell death Autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
    Autophagy, 6 (8), 1214-+
    DOI 10.4161/auto.6.8.13694
  19. Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
    Autophagy as a trigger for cell death: autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
    Autophagy, 6 (8), 1214-5
    DOI 10.4161/auto.6.8.13694, PubMed 20935512
  20. Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjørkøy G, Johansen T, Rusten TE, Brech A, Baehrecke EH, Stenmark H (2010)
    Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
    J Cell Biol, 190 (4), 523-31
    DOI 10.1083/jcb.201002035, PubMed 20713604
  21. Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A, Bjørkøy G, Johansen T (2010)
    FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
    J Cell Biol, 188 (2), 253-69
    DOI 10.1083/jcb.200907015, PubMed 20100911
  22. Pust S, Barth H, Sandvig K (2010)
    Clostridium botulinum C2 toxin is internalized by clathrin- and Rho-dependent mechanisms
    Cell Microbiol, 12 (12), 1809-20
    DOI 10.1111/j.1462-5822.2010.01512.x, PubMed 20690924
  23. Pust S, Dyve AB, Torgersen ML, van Deurs B, Sandvig K (2010)
    Interplay between toxin transport and flotillin localization
    PLoS One, 5 (1), e8844
    DOI 10.1371/journal.pone.0008844, PubMed 20107503
  24. Roxrud I, Stenmark H, Malerød L (2010)
    ESCRT & Co
    Biol Cell, 102 (5), 293-318
    DOI 10.1042/BC20090161, PubMed 20222872
  25. Rusten TE, Stenmark H (2010)
    p62, an autophagy hero or culprit?
    Nat Cell Biol, 12 (3), 207-9
    DOI 10.1038/ncb0310-207, PubMed 20190829
  26. Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
    PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
    Nat Cell Biol, 12 (4), 362-71
    DOI 10.1038/ncb2036, PubMed 20208530
  27. Sagona AP, Stenmark H (2010)
    Cytokinesis and cancer (vol 584, pg 2652, 2010)
    FEBS Lett., 584 (18), 4128
    DOI 10.1016/j.febslet.2010.08.016
  28. Sagona AP, Stenmark H (2010)
    Cytokinesis and cancer
    FEBS Lett, 584 (12), 2652-61
    DOI 10.1016/j.febslet.2010.03.044, PubMed 20371245
  29. Sandvig K, Torgersen ML, Engedal N, Skotland T, Iversen TG (2010)
    Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine
    FEBS Lett, 584 (12), 2626-34
    DOI 10.1016/j.febslet.2010.04.008, PubMed 20385131
  30. Seglen PO, Brinchmann MF (2010)
    Purification of autophagosomes from rat hepatocytes
    Autophagy, 6 (4), 542-7
    DOI 10.4161/auto.6.4.11272, PubMed 20505360
  31. Shimokawa N, Haglund K, Hölter SM, Grabbe C, Kirkin V, Koibuchi N, Schultz C, Rozman J, Hoeller D, Qiu CH, Londoño MB, Ikezawa J, Jedlicka P, Stein B, Schwarzacher SW, Wolfer DP, Ehrhardt N, Heuchel R, Nezis I, Brech A, Schmidt MHH, Fuchs H, Gailus-Durner V, Klingenspor M, Bogler O et al. (2010)
    CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice
    EMBO J, 29 (14), 2421-32
    DOI 10.1038/emboj.2010.120, PubMed 20551902
  32. Skotland T, Iversen TG, Sandvig K (2010)
    New metal-based nanoparticles for intravenous use: requirements for clinical success with focus on medical imaging
    Nanomedicine, 6 (6), 730-7
    DOI 10.1016/j.nano.2010.05.002, PubMed 20570639
  33. Stokke C, Waldminghaus T, Skarstad K (2010)
    Replication patterns and organization of replication forks in Vibrio cholerae
    Microbiology (Reading), 157 (Pt 3), 695-708
    DOI 10.1099/mic.0.045112-0, PubMed 21163839
  34. Stuffers S, Malerød L, Schink KO, Corvera S, Stenmark H, Brech A (2010)
    Time-resolved ultrastructural detection of phosphatidylinositol 3-phosphate
    J Histochem Cytochem, 58 (11), 1025-32
    DOI 10.1369/jhc.2010.955815, PubMed 20713985
  35. Teichmann B, Liu L, Schink KO, Bölker M (2010)
    Activation of the ustilagic acid biosynthesis gene cluster in Ustilago maydis by the C2H2 zinc finger transcription factor Rua1
    Appl Environ Microbiol, 76 (8), 2633-40
    DOI 10.1128/AEM.02211-09, PubMed 20173069
  36. Thoresen SB, Pedersen NM, Liestøl K, Stenmark H (2010)
    A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
    Exp Cell Res, 316 (20), 3368-78
    DOI 10.1016/j.yexcr.2010.07.008, PubMed 20643123
  37. Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2010)
    Functional characterization of the protein C A267T mutation: evidence for impaired secretion due to defective intracellular transport
    BMC Cell Biol, 11, 67
    DOI 10.1186/1471-2121-11-67, PubMed 20815936
  38. Torgersen ML, Engedal N, Bergan J, Sandvig K (2010)
    The Intracellular Journey of Shiga Toxins
    The Open Toxinology Journal, 3, 3-12
    PublikaID 24
  39. Torgersen ML, Engedal N, Pedersen AM, Husebye H, Espevik T, Sandvig K (2010)
    Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells
    FEMS Immunol Med Microbiol, 61 (1), 63-75
    DOI 10.1111/j.1574-695X.2010.00749.x, PubMed 21054580
  40. Utskarpen A, Massol R, van Deurs B, Lauvrak SU, Kirchhausen T, Sandvig K (2010)
    Shiga toxin increases formation of clathrin-coated pits through Syk kinase
    PLoS One, 5 (7), e10944
    DOI 10.1371/journal.pone.0010944, PubMed 20668539
  41. Waldminghaus T, Skarstad K (2010)
    ChIP on Chip: surprising results are often artifacts
    BMC Genomics, 11, 414
    DOI 10.1186/1471-2164-11-414, PubMed 20602746

Publications 2009

  1. Bjørkøy G, Lamark T, Pankiv S, Øvervatn A, Brech A, Johansen T (2009)
    Monitoring autophagic degradation of p62/SQSTM1
    Methods Enzymol, 452, 181-97
    DOI 10.1016/S0076-6879(08)03612-4, PubMed 19200883
  2. Boeneman K, Fossum S, Yang Y, Fingland N, Skarstad K, Crooke E (2009)
    Escherichia coli DnaA forms helical structures along the longitudinal cell axis distinct from MreB filaments
    Mol Microbiol, 72 (3), 645-57
    DOI 10.1111/j.1365-2958.2009.06674.x, PubMed 19400775
  3. Boye E, Grallert B (2009)
    In DNA replication, the early bird catches the worm
    Cell, 136 (5), 812-4
    DOI 10.1016/j.cell.2009.02.023, PubMed 19269359
  4. Boye E, Skjølberg HC, Grallert B (2009)
    Checkpoint regulation of DNA replication
    Methods Mol Biol, 521, 55-70
    DOI 10.1007/978-1-60327-815-7_4, PubMed 19563101
  5. Brech A, Ahlquist T, Lothe RA, Stenmark H (2009)
    Autophagy in tumour suppression and promotion
    Mol Oncol, 3 (4), 366-75
    DOI 10.1016/j.molonc.2009.05.007, PubMed 19559660
  6. Dyve AB, Bergan J, Utskarpen A, Sandvig K (2009)
    Sorting nexin 8 regulates endosome-to-Golgi transport
    Biochem Biophys Res Commun, 390 (1), 109-14
    DOI 10.1016/j.bbrc.2009.09.076, PubMed 19782049
  7. Døving KB, Sandvig K, Kasumyan A (2009)
    Ligand-specific induction of endocytosis in taste receptor cells
    J Exp Biol, 212 (Pt 1), 42-9
    DOI 10.1242/jeb.025700, PubMed 19088209
  8. Iversen TG, Frerker N, Sandvig K (2009)
    Quantum dot bioconjugates: uptake into cells and induction of changes in normal cellular transport
    San Jose, CA, USA, SPIE, 1, 7189[1], 71890T-9
    PublikaID 29
  9. Kaiser E, Pust S, Kroll C, Barth H (2009)
    Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells
    Cell Microbiol, 11 (5), 780-95
    DOI 10.1111/j.1462-5822.2009.01291.x, PubMed 19159389
  10. Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
    Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
    J Cell Sci, 122 (Pt 21), 3883-93
    DOI 10.1242/jcs.053801, PubMed 19808888
  11. Malerød L, Stenmark H (2009)
    ESCRTing membrane deformation
    Cell, 136 (1), 15-7
    DOI 10.1016/j.cell.2008.12.029, PubMed 19135881
  12. Morigen, Odsbu I, Skarstad K (2009)
    Growth rate dependent numbers of SeqA structures organize the multiple replication forks in rapidly growing Escherichia coli
    Genes Cells, 14 (5), 643-57
    DOI 10.1111/j.1365-2443.2009.01298.x, PubMed 19371375
  13. Nezis IP, Lamark T, Velentzas AD, Rusten TE, Bjørkøy G, Johansen T, Papassideri IS, Stravopodis DJ, Margaritis LH, Stenmark H, Brech A (2009)
    Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
    Autophagy, 5 (3), 298-302
    DOI 10.4161/auto.5.3.7454, PubMed 19066465
  14. Odsbu I, Morigen, Skarstad K (2009)
    A reduction in ribonucleotide reductase activity slows down the chromosome replication fork but does not change its localization
    PLoS One, 4 (10), e7617
    DOI 10.1371/journal.pone.0007617, PubMed 19898675
  15. Raiborg C, Stenmark H (2009)
    The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
    Nature, 458 (7237), 445-52
    DOI 10.1038/nature07961, PubMed 19325624
  16. Rodahl LM, Haglund K, Sem-Jacobsen C, Wendler F, Vincent JP, Lindmo K, Rusten TE, Stenmark H (2009)
    Disruption of Vps4 and JNK function in Drosophila causes tumour growth
    PLoS One, 4 (2), e4354
    DOI 10.1371/journal.pone.0004354, PubMed 19194501
  17. Rodahl LM, Stuffers S, Lobert VH, Stenmark H (2009)
    The role of ESCRT proteins in attenuation of cell signalling
    Biochem Soc Trans, 37 (Pt 1), 137-42
    DOI 10.1042/BST0370137, PubMed 19143618
  18. Roxrud I, Raiborg C, Gilfillan GD, Strømme P, Stenmark H (2009)
    Dual degradation mechanisms ensure disposal of NHE6 mutant protein associated with neurological disease
    Exp Cell Res, 315 (17), 3014-27
    DOI 10.1016/j.yexcr.2009.07.012, PubMed 19619532
  19. Rusten TE, Stenmark H (2009)
    How do ESCRT proteins control autophagy?
    J Cell Sci, 122 (Pt 13), 2179-83
    DOI 10.1242/jcs.050021, PubMed 19535733
  20. Raa H, Grimmer S, Schwudke D, Bergan J, Wälchli S, Skotland T, Shevchenko A, Sandvig K (2009)
    Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin
    Traffic, 10 (7), 868-82
    DOI 10.1111/j.1600-0854.2009.00919.x, PubMed 19453975
  21. Sandvig K, Bergan J, Dyve AB, Skotland T, Torgersen ML (2009)
    Endocytosis and retrograde transport of Shiga toxin
    Toxicon, 56 (7), 1181-5
    DOI 10.1016/j.toxicon.2009.11.021, PubMed 19951719
  22. Seglen PO, Øverbye A, Saetre F (2009)
    Sequestration assays for mammalian autophagy
    Methods Enzymol, 452, 63-83
    DOI 10.1016/S0076-6879(08)03605-7, PubMed 19200876
  23. Skjølberg HC, Fensgård O, Nilsen H, Grallert B, Boye E (2009)
    Global transcriptional response after exposure of fission yeast cells to ultraviolet light
    BMC Cell Biol, 10, 87
    DOI 10.1186/1471-2121-10-87, PubMed 20015352
  24. Skånland SS, Wälchli S, Brech A, Sandvig K (2009)
    SNX4 in complex with clathrin and dynein: implications for endosome movement
    PLoS One, 4 (6), e5935
    DOI 10.1371/journal.pone.0005935, PubMed 19529763
  25. Skånland SS, Wälchli S, Sandvig K (2009)
    β-arrestins attenuate p38-mediated endosome to Golgi transport
    Cell Microbiol, 11 (5), 796-807
    DOI 10.1111/j.1462-5822.2009.01292.x, PubMed 19159388
  26. Stenmark H (2009)
    Rab GTPases as coordinators of vesicle traffic
    Nat Rev Mol Cell Biol, 10 (8), 513-25
    DOI 10.1038/nrm2728, PubMed 19603039
  27. Stenmark H (2009)
    Seeing is believing
    Nat Rev Mol Cell Biol, 10 (9), 582
    DOI 10.1038/nrm2747, PubMed 19702012
  28. Stepankiw N, Kaidow A, Boye E, Bates D (2009)
    The right half of the Escherichia coli replication origin is not essential for viability, but facilitates multi-forked replication
    Mol Microbiol, 74 (2), 467-79
    DOI 10.1111/j.1365-2958.2009.06877.x, PubMed 19737351
  29. Stuffers S, Sem Wegner C, Stenmark H, Brech A (2009)
    Multivesicular endosome biogenesis in the absence of ESCRTs
    Traffic, 10 (7), 925-37
    DOI 10.1111/j.1600-0854.2009.00920.x, PubMed 19490536
  30. Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D (2009)
    Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
    J Cell Sci, 122 (Pt 14), 2413-23
    DOI 10.1242/jcs.046391, PubMed 19571114
  31. Waldminghaus T, Skarstad K (2009)
    The Escherichia coli SeqA protein
    Plasmid, 61 (3), 141-50
    DOI 10.1016/j.plasmid.2009.02.004, PubMed 19254745
  32. Wang J, Morigen (2009)
    BayesPI - a new model to study protein-DNA interactions: a case study of condition-specific protein binding parameters for Yeast transcription factors
    BMC Bioinformatics, 10, 345
    DOI 10.1186/1471-2105-10-345, PubMed 19857274
  33. Wegner CS, Malerød L, Pedersen NM, Progida C, Bakke O, Stenmark H, Brech A (2009)
    Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
    Histochem Cell Biol, 133 (1), 41-55
    DOI 10.1007/s00418-009-0643-8, PubMed 19830447
  34. Wälchli S, Aasheim HC, Skånland SS, Spilsberg B, Torgersen ML, Rosendal KR, Sandvig K (2009)
    Characterization of clathrin and Syk interaction upon Shiga toxin binding
    Cell Signal, 21 (7), 1161-8
    DOI 10.1016/j.cellsig.2009.03.005, PubMed 19289168
  35. Zakrzewska M, Wiedlocha A, Szlachcic A, Krowarsch D, Otlewski J, Olsnes S (2009)
    Increased protein stability of FGF1 can compensate for its reduced affinity for heparin
    J Biol Chem, 284 (37), 25388-403
    DOI 10.1074/jbc.M109.001289, PubMed 19574212
  36. Zakrzewska M, Zhen Y, Wiedlocha A, Olsnes S, Wesche J (2009)
    Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane
    Biochemistry, 48 (30), 7209-18
    DOI 10.1021/bi9007353, PubMed 19558187
  37. Zheng YT, Shahnazari S, Brech A, Lamark T, Johansen T, Brumell JH (2009)
    The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway
    J Immunol, 183 (9), 5909-16
    DOI 10.4049/jimmunol.0900441, PubMed 19812211
  38. Øverbye A, Seglen PO (2009)
    Phosphorylated and non-phosphorylated forms of catechol O-methyltransferase in rat liver, brain and other tissues
    Biochem J, 417 (2), 535-45
    DOI 10.1042/BJ20081284, PubMed 18831714

Publications 2008

  1. Bach T, Morigen, Skarstad K (2008)
    The initiator protein DnaA contributes to keeping new origins inactivated by promoting the presence of hemimethylated DNA
    J Mol Biol, 384 (5), 1076-85
    DOI 10.1016/j.jmb.2008.09.042, PubMed 18835566
  2. Bergeland T, Haugen L, Landsverk OJ, Stenmark H, Bakke O (2008)
    Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1
    EMBO Rep, 9 (2), 171-8
    DOI 10.1038/sj.embor.7401152, PubMed 18188183
  3. Bøe CA, Garcia I, Pai CC, Sharom JR, Skjølberg HC, Boye E, Kearsey S, Macneill SA, Tyers MD, Grallert B (2008)
    Rapid regulation of protein activity in fission yeast
    BMC Cell Biol, 9, 23
    DOI 10.1186/1471-2121-9-23, PubMed 18457584
  4. Cumming RC, Simonsen A, Finley KD (2008)
    Quantitative analysis of autophagic activity in Drosophila neural tissues by measuring the turnover rates of pathway substrates
    Methods Enzymol, 451, 639-51
    DOI 10.1016/S0076-6879(08)03235-7, PubMed 19185743
  5. Engedal N, Auberger P, Blomhoff HK (2008)
    Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly
    J Leukoc Biol, 85 (3), 469-80
    DOI 10.1189/jlb.1107790, PubMed 19112091
  6. Flåtten I, Morigen, Skarstad K (2008)
    DnaA protein interacts with RNA polymerase and partially protects it from the effect of rifampicin
    Mol Microbiol, 71 (4), 1018-30
    DOI 10.1111/j.1365-2958.2008.06585.x, PubMed 19170875
  7. Fossum S, De Pascale G, Weigel C, Messer W, Donadio S, Skarstad K (2008)
    A robust screen for novel antibiotics: specific knockout of the initiator of bacterial DNA replication
    FEMS Microbiol Lett, 281 (2), 210-4
    DOI 10.1111/j.1574-6968.2008.01103.x, PubMed 18312360
  8. Fuller RS (2008)
    A tribute to Arthur Kornberg 1918-2007
    Nat Struct Mol Biol, 15 (1), 2-17
    DOI 10.1038/nsmb0108-2, PubMed 18176549
  9. Gilfillan GD, Selmer KK, Roxrud I, Smith R, Kyllerman M, Eiklid K, Kroken M, Mattingsdal M, Egeland T, Stenmark H, Sjøholm H, Server A, Samuelsson L, Christianson A, Tarpey P, Whibley A, Stratton MR, Futreal PA, Teague J, Edkins S, Gecz J, Turner G, Raymond FL, Schwartz C, Stevenson RE et al. (2008)
    SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome
    Am J Hum Genet, 82 (4), 1003-10
    DOI 10.1016/j.ajhg.2008.01.013, PubMed 18342287
  10. Grallert B, Boye E (2008)
    The multiple facets of the intra-S checkpoint
    Cell Cycle, 7 (15), 2315-20
    DOI 10.4161/cc.6389, PubMed 18677104
  11. Grosso S, Volta V, Sala LA, Vietri M, Marchisio PC, Ron D, Biffo S (2008)
    PKCbetaII modulates translation independently from mTOR and through RACK1
    Biochem J, 415 (1), 77-85
    DOI 10.1042/BJ20080463, PubMed 18557705
  12. Grosso S, Volta V, Vietri M, Gorrini C, Marchisio PC, Biffo S (2008)
    Eukaryotic ribosomes host PKC activity
    Biochem Biophys Res Commun, 376 (1), 65-9
    DOI 10.1016/j.bbrc.2008.08.118, PubMed 18768137
  13. Haugsten EM, Malecki J, Bjørklund SM, Olsnes S, Wesche J (2008)
    Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis
    Mol Biol Cell, 19 (8), 3390-403
    DOI 10.1091/mbc.e07-12-1219, PubMed 18480409
  14. Heine K, Pust S, Enzenmüller S, Barth H (2008)
    ADP-ribosylation of actin by the Clostridium botulinum C2 toxin in mammalian cells results in delayed caspase-dependent apoptotic cell death
    Infect Immun, 76 (10), 4600-8
    DOI 10.1128/IAI.00651-08, PubMed 18710868
  15. Klionsky DJ, Elazar Z, Seglen PO, Rubinsztein DC (2008)
    Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?
    Autophagy, 4 (7), 849-50
    DOI 10.4161/auto.6845, PubMed 18758232
  16. Krohn M, Skjølberg HC, Soltani H, Grallert B, Boye E (2008)
    The G1-S checkpoint in fission yeast is not a general DNA damage checkpoint
    J Cell Sci, 121 (Pt 24), 4047-54
    DOI 10.1242/jcs.035428, PubMed 19033384
  17. Lindmo K, Brech A, Finley KD, Gaumer S, Contamine D, Rusten TE, Stenmark H (2008)
    The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
    Autophagy, 4 (4), 500-6
    DOI 10.4161/auto.5829, PubMed 18326940
  18. Miaczynska M, Stenmark H (2008)
    Mechanisms and functions of endocytosis
    J Cell Biol, 180 (1), 7-11
    DOI 10.1083/jcb.200711073, PubMed 18195098
  19. Morrison HA, Dionne H, Rusten TE, Brech A, Fisher WW, Pfeiffer BD, Celniker SE, Stenmark H, Bilder D (2008)
    Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45
    Mol Biol Cell, 19 (10), 4167-76
    DOI 10.1091/mbc.e08-07-0716, PubMed 18685079
  20. Nezis IP, Papassideri I (2008)
    Monitoring autophagy in insect eggs
    Methods Enzymol, 451, 669-83
    DOI 10.1016/S0076-6879(08)03237-0, PubMed 19185745
  21. Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A (2008)
    Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
    J Cell Biol, 180 (6), 1065-71
    DOI 10.1083/jcb.200711108, PubMed 18347073
  22. Raposo G, Stenmark H (2008)
    Membranes and organelles
    Curr Opin Cell Biol, 20 (4), 357-9
    DOI 10.1016/j.ceb.2008.06.005, PubMed 18588977
  23. Rusten TE, Filimonenko M, Rodahl LM, Stenmark H, Simonsen A (2008)
    ESCRTing autophagic clearance of aggregating proteins
    Autophagy, 4 (2), 233-236
    DOI 10.4161/auto.5396
  24. Rusten TE, Simonsen A (2008)
    ESCRT functions in autophagy and associated disease
    Cell Cycle, 7 (9), 1166-72
    DOI 10.4161/cc.7.9.5784, PubMed 18418046
  25. Sandvig K, Torgersen ML, Raa HA, van Deurs B (2008)
    Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity
    Histochem Cell Biol, 129 (3), 267-76
    DOI 10.1007/s00418-007-0376-5, PubMed 18193449
  26. Sandvig K, van Deurs B (2008)
    Cell biology: Viruses in camouflage
    Nature, 453 (7194), 466-7
    DOI 10.1038/453466a, PubMed 18497813
  27. Simonsen A, Stenmark H (2008)
    Self-eating from an ER-associated cup
    J Cell Biol, 182 (4), 621-2
    DOI 10.1083/jcb.200807061, PubMed 18725534
  28. Stuffers S, Brech A, Stenmark H (2008)
    ESCRT proteins in physiology and disease
    Exp Cell Res, 315 (9), 1619-26
    DOI 10.1016/j.yexcr.2008.10.013, PubMed 19013455
  29. Sørensen V, Zhen Y, Zakrzewska M, Haugsten EM, Wälchli S, Nilsen T, Olsnes S, Wiedlocha A (2008)
    Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus
    Mol Cell Biol, 28 (12), 4129-41
    DOI 10.1128/MCB.02117-07, PubMed 18411303
  30. Tekle C, Deurs Bv, Sandvig K, Iversen TG (2008)
    Cellular trafficking of quantum dot-ligand bioconjugates and their induction of changes in normal routing of unconjugated ligands
    Nano Lett, 8 (7), 1858-65
    DOI 10.1021/nl0803848, PubMed 18570482
  31. Umebayashi K, Stenmark H, Yoshimori T (2008)
    Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
    Mol Biol Cell, 19 (8), 3454-62
    DOI 10.1091/mbc.e07-10-0988, PubMed 18508924
  32. Zakrzewska M, Marcinkowska E, Wiedlocha A (2008)
    FGF-1: from biology through engineering to potential medical applications
    Crit Rev Clin Lab Sci, 45 (1), 91-135
    DOI 10.1080/10408360701713120, PubMed 18293181

Publications 2007

  1. Bertelsen V, Breen K, Sandvig K, Stang E, Madshus IH (2007)
    The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis
    Exp Cell Res, 313 (8), 1696-709
    DOI 10.1016/j.yexcr.2007.02.017, PubMed 17382318
  2. Citores L, Bai L, Sørensen V, Olsnes S (2007)
    Fibroblast growth factor receptor-induced phosphorylation of STAT1 at the Golgi apparatus without translocation to the nucleus
    J Cell Physiol, 212 (1), 148-56
    DOI 10.1002/jcp.21014, PubMed 17311277
  3. Feugaing DD, Tammi R, Echtermeyer FG, Stenmark H, Kresse H, Smollich M, Schönherr E, Kiesel L, Götte M (2007)
    Endocytosis of the dermatan sulfate proteoglycan decorin utilizes multiple pathways and is modulated by epidermal growth factor receptor signaling
    Biochimie, 89 (5), 637-57
    DOI 10.1016/j.biochi.2006.12.012, PubMed 17335953
  4. Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A (2007)
    Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
    J Cell Biol, 179 (3), 485-500
    DOI 10.1083/jcb.200702115, PubMed 17984323
  5. Fort J, de la Ballina LR, Burghardt HE, Ferrer-Costa C, Turnay J, Ferrer-Orta C, Usón I, Zorzano A, Fernández-Recio J, Orozco M, Lizarbe MA, Fita I, Palacín M (2007)
    The structure of human 4F2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane
    J Biol Chem, 282 (43), 31444-52
    DOI 10.1074/jbc.M704524200, PubMed 17724034
  6. Fossum S, Crooke E, Skarstad K (2007)
    Organization of sister origins and replisomes during multifork DNA replication in Escherichia coli
    EMBO J, 26 (21), 4514-22
    DOI 10.1038/sj.emboj.7601871, PubMed 17914458
  7. Grallert B, Boye E (2007)
    The Gcn2 kinase as a cell cycle regulator
    Cell Cycle, 6 (22), 2768-72
    DOI 10.4161/cc.6.22.4933, PubMed 17986863
  8. Haglund K, Rusten TE, Stenmark H (2007)
    Aberrant receptor signaling and trafficking as mechanisms in oncogenesis
    Crit Rev Oncog, 13 (1), 39-74
    DOI 10.1615/critrevoncog.v13.i1.20, PubMed 17956217
  9. Hughes T, Rusten TE (2007)
    Origin and evolution of self-consumption: autophagy
    Adv Exp Med Biol, 607, 111-8
    DOI 10.1007/978-0-387-74021-8_9, PubMed 17977463
  10. Klionsky DJ, Cuervo AM, Dunn WA, Levine B, van der Klei I, Seglen PO (2007)
    How shall I eat thee?
    Autophagy, 3 (5), 413-6
    DOI 10.4161/auto.4377, PubMed 17568180
  11. Kurmanova A, Llorente A, Polesskaya A, Garred O, Olsnes S, Kozlov J, Sandvig K (2007)
    Structural requirements for furin-induced cleavage and activation of Shiga toxin
    Biochem Biophys Res Commun, 357 (1), 144-9
    DOI 10.1016/j.bbrc.2007.03.110, PubMed 17407762
  12. Llorente A, van Deurs B, Sandvig K (2007)
    Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells
    Eur J Cell Biol, 86 (7), 405-15
    DOI 10.1016/j.ejcb.2007.05.001, PubMed 17601634
  13. Malerød L, Stenmark H (2007)
    ESCRTs
    Curr Biol, 17 (2), R42-3
    DOI 10.1016/j.cub.2006.12.009, PubMed 17240322
  14. Malerød L, Stuffers S, Brech A, Stenmark H (2007)
    Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation
    Traffic, 8 (11), 1617-29
    DOI 10.1111/j.1600-0854.2007.00630.x, PubMed 17714434
  15. Martín-Acebes MA, González-Magaldi M, Sandvig K, Sobrino F, Armas-Portela R (2007)
    Productive entry of type C foot-and-mouth disease virus into susceptible cultured cells requires clathrin and is dependent on the presence of plasma membrane cholesterol
    Virology, 369 (1), 105-18
    DOI 10.1016/j.virol.2007.07.021, PubMed 17714753
  16. Nilsen T, Rosendal KR, Sørensen V, Wesche J, Olsnes S, Wiedłocha A (2007)
    A nuclear export sequence located on a beta-strand in fibroblast growth factor-1
    J Biol Chem, 282 (36), 26245-56
    DOI 10.1074/jbc.M611234200, PubMed 17616529
  17. Norris V, den Blaauwen T, Cabin-Flaman A, Doi RH, Harshey R, Janniere L, Jimenez-Sanchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Saier M, Skarstad K (2007)
    Functional taxonomy of bacterial hyperstructures
    Microbiol Mol Biol Rev, 71 (1), 230-53
    DOI 10.1128/MMBR.00035-06, PubMed 17347523
  18. Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T (2007)
    p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    J Biol Chem, 282 (33), 24131-45
    DOI 10.1074/jbc.M702824200, PubMed 17580304
  19. Progida C, Malerød L, Stuffers S, Brech A, Bucci C, Stenmark H (2007)
    RILP is required for the proper morphology and function of late endosomes
    J Cell Sci, 120 (Pt 21), 3729-37
    DOI 10.1242/jcs.017301, PubMed 17959629
  20. Raiborg C, Malerød L, Pedersen NM, Stenmark H (2007)
    Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
    Exp Cell Res, 314 (4), 801-13
    DOI 10.1016/j.yexcr.2007.10.014, PubMed 18031739
  21. Rusten TE, Stenmark H (2007)
    Developmental biology: moonlighting at the pole
    Nature, 445 (7127), 497-9
    DOI 10.1038/445497a, PubMed 17268460
  22. Rusten TE, Vaccari T, Lindmo K, Rodahl LM, Nezis IP, Sem-Jacobsen C, Wendler F, Vincent JP, Brech A, Bilder D, Stenmark H (2007)
    ESCRTs and Fab1 regulate distinct steps of autophagy
    Curr Biol, 17 (20), 1817-25
    DOI 10.1016/j.cub.2007.09.032, PubMed 17935992
  23. Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD (2007)
    Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
    Autophagy, 4 (2), 176-84
    DOI 10.4161/auto.5269, PubMed 18059160
  24. Simonsen A, Cumming RC, Lindmo K, Galaviz V, Cheng S, Rusten TE, Finley KD (2007)
    Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles
    Genetics, 176 (2), 1283-97
    DOI 10.1534/genetics.106.065011, PubMed 17435236
  25. Simonsen A, Stenmark H (2007)
    Stimulating the cell's appetite for itself
    Nat Chem Biol, 3 (6), 304-6
    DOI 10.1038/nchembio0607-304, PubMed 17510644
  26. Skånland SS, Wälchli S, Utskarpen A, Wandinger-Ness A, Sandvig K (2007)
    Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins
    Traffic, 8 (3), 297-309
    DOI 10.1111/j.1600-0854.2006.00527.x, PubMed 17319803
  27. Spilsberg B, Llorente A, Sandvig K (2007)
    Polyunsaturated fatty acids regulate Shiga toxin transport
    Biochem Biophys Res Commun, 364 (2), 283-8
    DOI 10.1016/j.bbrc.2007.09.126, PubMed 17942073
  28. Torgersen ML, Wälchli S, Grimmer S, Skånland SS, Sandvig K (2007)
    Protein kinase Cdelta is activated by Shiga toxin and regulates its transport
    J Biol Chem, 282 (22), 16317-28
    DOI 10.1074/jbc.M610886200, PubMed 17403690
  29. Tvegård T, Soltani H, Skjølberg HC, Krohn M, Nilssen EA, Kearsey SE, Grallert B, Boye E (2007)
    A novel checkpoint mechanism regulating the G1/S transition
    Genes Dev, 21 (6), 649-54
    DOI 10.1101/gad.421807, PubMed 17369398
  30. Utskarpen A, Slagsvold HH, Dyve AB, Skånland SS, Sandvig K (2007)
    SNX1 and SNX2 mediate retrograde transport of Shiga toxin
    Biochem Biophys Res Commun, 358 (2), 566-70
    DOI 10.1016/j.bbrc.2007.04.159, PubMed 17498660
  31. Zhen Y, Sørensen V, Jin Y, Suo Z, Wiedłocha A (2007)
    Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
    Oncogene, 26 (44), 6372-85
    DOI 10.1038/sj.onc.1210473, PubMed 17533378
  32. Øverbye A, Fengsrud M, Seglen PO (2007)
    Proteomic analysis of membrane-associated proteins from rat liver autophagosomes
    Autophagy, 3 (4), 300-22
    DOI 10.4161/auto.3910, PubMed 17377489

Publications 2006

  1. Bache KG (2006)
    The function of ubiquitin-binding protein complexes in endocytic downregulation of growth factor receptors
    Crit Rev Oncog, 12 (3-4), 301; discussion 301-2
    DOI 10.1615/critrevoncog.v12.i3-4.90, PubMed 17425510
  2. Bache KG, Stuffers S, Malerød L, Slagsvold T, Raiborg C, Lechardeur D, Wälchli S, Lukacs GL, Brech A, Stenmark H (2006)
    The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
    Mol Biol Cell, 17 (6), 2513-23
    DOI 10.1091/mbc.e05-10-0915, PubMed 16554368
  3. Boye E (2006)
    DisA, a busy bee that monitors chromosome integrity
    Cell, 125 (4), 641-3
    DOI 10.1016/j.cell.2006.05.004, PubMed 16713555
  4. Cabezas A, Pattni K, Stenmark H (2006)
    Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
    Gene, 371 (1), 34-41
    DOI 10.1016/j.gene.2005.11.009, PubMed 16448788
  5. Gon S, Camara JE, Klungsøyr HK, Crooke E, Skarstad K, Beckwith J (2006)
    A novel regulatory mechanism couples deoxyribonucleotide synthesis and DNA replication in Escherichia coli
    EMBO J, 25 (5), 1137-47
    DOI 10.1038/sj.emboj.7600990, PubMed 16482221
  6. Grimmer S, Spilsberg B, Hanada K, Sandvig K (2006)
    Depletion of sphingolipids facilitates endosome to Golgi transport of ricin
    Traffic, 7 (9), 1243-53
    DOI 10.1111/j.1600-0854.2006.00456.x, PubMed 16919154
  7. Haglund K, Stenmark H (2006)
    Working out coupled monoubiquitination
    Nat Cell Biol, 8 (11), 1218-9
    DOI 10.1038/ncb1106-1218, PubMed 17077855
  8. Hecker CM, Rabiller M, Haglund K, Bayer P, Dikic I (2006)
    Specification of SUMO1- and SUMO2-interacting motifs
    J Biol Chem, 281 (23), 16117-27
    DOI 10.1074/jbc.M512757200, PubMed 16524884
  9. Hirano S, Kawasaki M, Ura H, Kato R, Raiborg C, Stenmark H, Wakatsuki S (2006)
    Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
    Nat Struct Mol Biol, 13 (3), 272-7
    DOI 10.1038/nsmb1051, PubMed 16462748
  10. Hirano S, Suzuki N, Slagsvold T, Kawasaki M, Trambaiolo D, Kato R, Stenmark H, Wakatsuki S (2006)
    Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain
    Nat Struct Mol Biol, 13 (11), 1031-2
    DOI 10.1038/nsmb1163, PubMed 17057714
  11. Hoeller D, Crosetto N, Blagoev B, Raiborg C, Tikkanen R, Wagner S, Kowanetz K, Breitling R, Mann M, Stenmark H, Dikic I (2006)
    Regulation of ubiquitin-binding proteins by monoubiquitination
    Nat Cell Biol, 8 (2), 163-9
    DOI 10.1038/ncb1354, PubMed 16429130
  12. Hollås H, Aukrust I, Grimmer S, Strand E, Flatmark T, Vedeler A (2006)
    Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA
    Biochim Biophys Acta, 1763 (11), 1325-34
    DOI 10.1016/j.bbamcr.2006.08.043, PubMed 17045350
  13. Husebye H, Halaas Ø, Stenmark H, Tunheim G, Sandanger Ø, Bogen B, Brech A, Latz E, Espevik T (2006)
    Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
    EMBO J, 25 (4), 683-92
    DOI 10.1038/sj.emboj.7600991, PubMed 16467847
  14. Huynh T, Wälchli S, Sioud M (2006)
    Transcriptional targeting of small interfering RNAs into cancer cells
    Biochem Biophys Res Commun, 350 (4), 854-9
    DOI 10.1016/j.bbrc.2006.09.127, PubMed 17034763
  15. Johannessen LE, Pedersen NM, Pedersen KW, Madshus IH, Stang E (2006)
    Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits
    Mol Cell Biol, 26 (2), 389-401
    DOI 10.1128/MCB.26.2.389-401.2006, PubMed 16382132
  16. Kazazic M, Roepstorff K, Johannessen LE, Pedersen NM, van Deurs B, Stang E, Madshus IH (2006)
    EGF-induced activation of the EGF receptor does not trigger mobilization of caveolae
    Traffic, 7 (11), 1518-27
    DOI 10.1111/j.1600-0854.2006.00487.x, PubMed 16984407
  17. Khnykin D, Olsnes S (2006)
    Reduced binding of FGF1 to mutant fibroblast growth factor receptor 3
    Growth Factors, 24 (2), 111-9
    DOI 10.1080/08977190600621388, PubMed 16801131
  18. Klokk TI, Kurys P, Elbi C, Nagaich AK, Hendarwanto A, Slagsvold T, Chang CY, Hager GL, Saatcioglu F (2006)
    Ligand-specific dynamics of the androgen receptor at its response element in living cells
    Mol Cell Biol, 27 (5), 1823-43
    DOI 10.1128/MCB.01297-06, PubMed 17189428
  19. Leithe E, Brech A, Rivedal E (2006)
    Endocytic processing of connexin43 gap junctions: a morphological study
    Biochem J, 393 (Pt 1), 59-67
    DOI 10.1042/BJ20050674, PubMed 16162097
  20. Lindmo K, Simonsen A, Brech A, Finley K, Rusten TE, Stenmark H (2006)
    A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
    Exp Cell Res, 312 (11), 2018-27
    DOI 10.1016/j.yexcr.2006.03.002, PubMed 16600212
  21. Lindmo K, Stenmark H (2006)
    Regulation of membrane traffic by phosphoinositide 3-kinases
    J Cell Sci, 119 (Pt 4), 605-14
    DOI 10.1242/jcs.02855, PubMed 16467569
  22. Lindmo K, Stenmark H (2006)
    How a RING finger protein and a steroid hormone control autophagy
    Autophagy, 2 (4), 321-2
    DOI 10.4161/auto.3091, PubMed 16874068
  23. Marcinkowska E, Superat K, Wiedłocha A (2006)
    FGF-1 as a possible carrier for targeted drug delivery
    Oncol Res, 16 (1), 27-34
    DOI 10.3727/000000006783981242, PubMed 16783965
  24. Michaelsen TE, Thommesen JE, Ihle O, Gregers TF, Sandin RH, Brekke OH, Sandlie I (2006)
    A mutant human IgG molecule with only one C1q binding site can activate complement and induce lysis of target cells
    Eur J Immunol, 36 (1), 129-38
    DOI 10.1002/eji.200535178, PubMed 16323243
  25. Myromslien FD, Grøvdal LM, Raiborg C, Stenmark H, Madshus IH, Stang E (2006)
    Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
    Exp Cell Res, 312 (16), 3036-48
    DOI 10.1016/j.yexcr.2006.06.004, PubMed 16859684
  26. Norlén L, Gil IP, Simonsen A, Descouts P (2006)
    Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films
    J Struct Biol, 158 (3), 386-400
    DOI 10.1016/j.jsb.2006.12.006, PubMed 17287132
  27. Raiborg C (2006)
    Hrs makes receptors silent: a key to endosomal protein sorting
    Crit Rev Oncog, 12 (3-4), 295, discussion 295-6
    DOI 10.1615/critrevoncog.v12.i3-4.70, PubMed 17425508
  28. Raiborg C, Slagsvold T, Stenmark H (2006)
    A new side to ubiquitin
    Trends Biochem Sci, 31 (10), 541-4
    DOI 10.1016/j.tibs.2006.07.009, PubMed 16901703
  29. Raiborg C, Wesche J, Malerød L, Stenmark H (2006)
    Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
    J Cell Sci, 119 (Pt 12), 2414-24
    DOI 10.1242/jcs.02978, PubMed 16720641
  30. Ralph E, Boye E, Kearsey SE (2006)
    DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1
    EMBO Rep, 7 (11), 1134-9
    DOI 10.1038/sj.embor.7400827, PubMed 17039252
  31. Rusten TE, Rodahl LM, Pattni K, Englund C, Samakovlis C, Dove S, Brech A, Stenmark H (2006)
    Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
    Mol Biol Cell, 17 (9), 3989-4001
    DOI 10.1091/mbc.e06-03-0239, PubMed 16837550
  32. Rusten TE, Stenmark H (2006)
    Analyzing phosphoinositides and their interacting proteins
    Nat Methods, 3 (4), 251-8
    DOI 10.1038/nmeth867, PubMed 16554828
  33. Rutherford AC, Traer C, Wassmer T, Pattni K, Bujny MV, Carlton JG, Stenmark H, Cullen PJ (2006)
    The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
    J Cell Sci, 119 (Pt 19), 3944-57
    DOI 10.1242/jcs.03153, PubMed 16954148
  34. Shahzidi S, Stokke T, Soltani H, Nesland JM, Peng Q (2006)
    Induction of apoptosis by hexaminolevulinate-mediated photodynamic therapy in human colon carcinoma cell line 320DM
    J Environ Pathol Toxicol Oncol, 25 (1-2), 159-71
    DOI 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.90, PubMed 16566715
  35. Slagsvold T, Marchese A, Brech A, Stenmark H (2006)
    CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
    EMBO J, 25 (16), 3738-49
    DOI 10.1038/sj.emboj.7601267, PubMed 16888620
  36. Slagsvold T, Pattni K, Malerød L, Stenmark H (2006)
    Endosomal and non-endosomal functions of ESCRT proteins
    Trends Cell Biol, 16 (6), 317-26
    DOI 10.1016/j.tcb.2006.04.004, PubMed 16716591
  37. Slominska-Wojewodzka M, Gregers TF, Wälchli S, Sandvig K (2006)
    EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol
    Mol Biol Cell, 17 (4), 1664-75
    DOI 10.1091/mbc.e05-10-0961, PubMed 16452630
  38. Sørensen V, Nilsen T, Wiedłocha A (2006)
    Functional diversity of FGF-2 isoforms by intracellular sorting
    Bioessays, 28 (5), 504-14
    DOI 10.1002/bies.20405, PubMed 16615083
  39. Sørensen V, Wiedlocha A, Haugsten EM, Khnykin D, Wesche J, Olsnes S (2006)
    Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail
    J Cell Sci, 119 (Pt 20), 4332-41
    DOI 10.1242/jcs.03209, PubMed 17003104
  40. Utskarpen A, Slagsvold HH, Iversen TG, Wälchli S, Sandvig K (2006)
    Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'
    Traffic, 7 (6), 663-72
    DOI 10.1111/j.1600-0854.2006.00418.x, PubMed 16683916
  41. Wesche J, Małecki J, Wiedłocha A, Skjerpen CS, Claus P, Olsnes S (2006)
    FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus
    J Biol Chem, 281 (16), 11405-12
    DOI 10.1074/jbc.M600477200, PubMed 16495214
  42. Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2006)
    Structural requirements of FGF-1 for receptor binding and translocation into cells
    Biochemistry, 45 (51), 15338-48
    DOI 10.1021/bi0618114, PubMed 17176056

Publications 2005

  1. Bach T, Skarstad K (2005)
    An oriC-like distribution of GATC sites mediates full sequestration of non-origin sequences in Escherichia coli
    J Mol Biol, 350 (1), 7-11
    DOI 10.1016/j.jmb.2005.04.055, PubMed 15922360
  2. Bates D, Epstein J, Boye E, Fahrner K, Berg H, Kleckner N (2005)
    The Escherichia coli baby cell column: a novel cell synchronization method provides new insight into the bacterial cell cycle
    Mol Microbiol, 57 (2), 380-91
    DOI 10.1111/j.1365-2958.2005.04693.x, PubMed 15978072
  3. Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T (2005)
    p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    J Cell Biol, 171 (4), 603-14
    DOI 10.1083/jcb.200507002, PubMed 16286508
  4. Cabezas A, Bache KG, Brech A, Stenmark H (2005)
    Alix regulates cortical actin and the spatial distribution of endosomes
    J Cell Sci, 118 (Pt 12), 2625-35
    DOI 10.1242/jcs.02382, PubMed 15914539
  5. Canales J, Cabezas A, Pinto RM, Cameselle JC (2005)
    Fluorimetric HPLC detection of endogenous riboflavin 4',5'-cyclic phosphate in rat liver at nanomolar concentrations
    Anal Biochem, 341 (2), 214-9
    DOI 10.1016/j.ab.2005.01.060, PubMed 15907866
  6. Drevon T, Slagsvold T (2005)
    When and from whom do female pied flycatchers (Ficedula hypoleuca) solicit copulations
    Behaviour, 142, 1059-1076
    DOI 10.1163/156853905774405335
  7. Grimmer S, Ying M, Wälchli S, van Deurs B, Sandvig K (2005)
    Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism
    Traffic, 6 (2), 144-56
    DOI 10.1111/j.1600-0854.2005.00258.x, PubMed 15634214
  8. Guerra L, Teter K, Lilley BN, Stenerlöw B, Holmes RK, Ploegh HL, Sandvig K, Thelestam M, Frisan T (2005)
    Cellular internalization of cytolethal distending toxin: a new end to a known pathway
    Cell Microbiol, 7 (7), 921-34
    DOI 10.1111/j.1462-5822.2005.00520.x, PubMed 15953025
  9. Haugsten EM, Sørensen V, Brech A, Olsnes S, Wesche J (2005)
    Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors
    J Cell Sci, 118 (Pt 17), 3869-81
    DOI 10.1242/jcs.02509, PubMed 16091423
  10. Hetz C, Russelakis-Carneiro M, Wälchli S, Carboni S, Vial-Knecht E, Maundrell K, Castilla J, Soto C (2005)
    The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity
    J Neurosci, 25 (11), 2793-802
    DOI 10.1523/JNEUROSCI.4090-04.2005, PubMed 15772339
  11. Hoepfner S, Severin F, Cabezas A, Habermann B, Runge A, Gillooly D, Stenmark H, Zerial M (2005)
    Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B
    Cell, 121 (3), 437-50
    DOI 10.1016/j.cell.2005.02.017, PubMed 15882625
  12. Hommelgaard AM, Roepstorff K, Vilhardt F, Torgersen ML, Sandvig K, van Deurs B (2005)
    Caveolae: stable membrane domains with a potential for internalization
    Traffic, 6 (9), 720-4
    DOI 10.1111/j.1600-0854.2005.00314.x, PubMed 16101676
  13. Høiseth G, Olsnes S (2005)
    [Ricin--a therapeutic agent and a biological weapon]
    Tidsskr Nor Laegeforen, 125 (18), 2477-9
    PubMed 16186864
  14. Ibrahim SO, Miron T, Krohn M, Amaratunga AN, Warnakulasauriya S, Vasstrand EN (2005)
    Tumour-associated Proteins in Oral Squamous Cell Carcinomas by Proteomics
    Cancer Genomics Proteomics, 2 (6), 353-363
    PubMed 31394652
  15. Johannessen LE, Slagsvold T, Hansen BT, Lifjeld JT (2005)
    Manipulation of male quality in wild tits: effects on paternity loss
    Behav. Ecol., 16 (4), 747-754
    DOI 10.1093/beheco/ari048
  16. Korobko E, Kiselev S, Olsnes S, Stenmark H, Korobko I (2005)
    The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5delta differ in their ability to interact with the small GTPase Rab4
    FEBS J, 272 (1), 37-46
    DOI 10.1111/j.1742-4658.2004.04387.x, PubMed 15634330
  17. Lauvrak SU, Wälchli S, Iversen TG, Slagsvold HH, Torgersen ML, Spilsberg B, Sandvig K (2005)
    Shiga toxin regulates its entry in a Syk-dependent manner
    Mol Biol Cell, 17 (3), 1096-109
    DOI 10.1091/mbc.e05-08-0766, PubMed 16371508
  18. Lindstad RI, Sylte I, Mikalsen SO, Seglen PO, Berg E, Winberg JO (2005)
    Pancreatic trypsin activates human promatrix metalloproteinase-2
    J Mol Biol, 350 (4), 682-98
    DOI 10.1016/j.jmb.2005.05.018, PubMed 15950241
  19. Longva KE, Pedersen NM, Haslekås C, Stang E, Madshus IH (2005)
    Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2
    Int J Cancer, 116 (3), 359-67
    DOI 10.1002/ijc.21015, PubMed 15800944
  20. Morigen, Molina F, Skarstad K (2005)
    Deletion of the datA site does not affect once-per-cell-cycle timing but induces rifampin-resistant replication
    J Bacteriol, 187 (12), 3913-20
    DOI 10.1128/JB.187.12.3913-3920.2005, PubMed 15939703
  21. Odsbu I, Klungsøyr HK, Fossum S, Skarstad K (2005)
    Specific N-terminal interactions of the Escherichia coli SeqA protein are required to form multimers that restrain negative supercoils and form foci
    Genes Cells, 10 (11), 1039-49
    DOI 10.1111/j.1365-2443.2005.00898.x, PubMed 16236133
  22. Samari HR, Møller MT, Holden L, Asmyhr T, Seglen PO (2005)
    Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins
    Biochem J, 386 (Pt 2), 237-44
    DOI 10.1042/BJ20040609, PubMed 15461583
  23. Sandvig K, van Deurs B (2005)
    Delivery into cells: lessons learned from plant and bacterial toxins
    Gene Ther, 12 (11), 865-72
    DOI 10.1038/sj.gt.3302525, PubMed 15815697
  24. Sioud M, Wälchli S (2005)
    Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs
    Methods Mol Biol, 309, 83-91
    DOI 10.1385/1-59259-935-4:083, PubMed 15990399
  25. Slagsvold T, Aasland R, Hirano S, Bache KG, Raiborg C, Trambaiolo D, Wakatsuki S, Stenmark H (2005)
    Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain
    J Biol Chem, 280 (20), 19600-6
    DOI 10.1074/jbc.M501510200, PubMed 15755741
  26. Sneve ML, Øverbye A, Fengsrud M, Seglen PO (2005)
    Comigration of two autophagosome-associated dehydrogenases on two-dimensional polyacrylamide gels
    Autophagy, 1 (3), 157-62
    DOI 10.4161/auto.1.3.2037, PubMed 16874067
  27. Spilsberg B, Hanada K, Sandvig K (2005)
    Diphtheria toxin translocation across cellular membranes is regulated by sphingolipids
    Biochem Biophys Res Commun, 329 (2), 465-73
    DOI 10.1016/j.bbrc.2005.02.005, PubMed 15737610
  28. Spilsberg B, Sandvig K, Wälchli S (2005)
    Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria
    Toxicon, 46 (8), 900-6
    DOI 10.1016/j.toxicon.2005.08.015, PubMed 16260019
  29. Stige LC, Slagsvold T, Vollestad LA (2005)
    Individual fluctuating asymmetry in pied flycatchers (Ficedula hypoleuca) persists across moults, but is not heritable and not related to fitness
    Evol. Ecol. Res., 7 (3), 381-406
  30. Torgersen ML, Lauvrak SU, Sandvig K (2005)
    The A-subunit of surface-bound Shiga toxin stimulates clathrin-dependent uptake of the toxin
    FEBS J, 272 (16), 4103-13
    DOI 10.1111/j.1742-4658.2005.04835.x, PubMed 16098193
  31. Voigt B, Timmers AC, Samaj J, Hlavacka A, Ueda T, Preuss M, Nielsen E, Mathur J, Emans N, Stenmark H, Nakano A, Baluska F, Menzel D (2005)
    Actin-based motility of endosomes is linked to the polar tip growth of root hairs
    Eur J Cell Biol, 84 (6), 609-21
    DOI 10.1016/j.ejcb.2004.12.029, PubMed 16032929
  32. Wesche J, Małecki J, Wiedłocha A, Ehsani M, Marcinkowska E, Nilsen T, Olsnes S (2005)
    Two nuclear localization signals required for transport from the cytosol to the nucleus of externally added FGF-1 translocated into cells
    Biochemistry, 44 (16), 6071-80
    DOI 10.1021/bi047403m, PubMed 15835896
  33. Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2005)
    Highly stable mutants of human fibroblast growth factor-1 exhibit prolonged biological action
    J Mol Biol, 352 (4), 860-75
    DOI 10.1016/j.jmb.2005.07.066, PubMed 16126225

Publications 2004

  1. Bach T, Skarstad K (2004)
    Re-replication from non-sequesterable origins generates three-nucleoid cells which divide asymmetrically
    Mol Microbiol, 51 (6), 1589-600
    DOI 10.1111/j.1365-2958.2003.03943.x, PubMed 15009887
  2. Bache KG, Slagsvold T, Cabezas A, Rosendal KR, Raiborg C, Stenmark H (2004)
    The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
    Mol Biol Cell, 15 (9), 4337-46
    DOI 10.1091/mbc.e04-03-0250, PubMed 15240819
  3. Bache KG, Slagsvold T, Stenmark H (2004)
    Defective downregulation of receptor tyrosine kinases in cancer
    EMBO J, 23 (14), 2707-12
    DOI 10.1038/sj.emboj.7600292, PubMed 15229652
  4. Birkeland HC, Stenmark H (2004)
    Protein targeting to endosomes and phagosomes via FYVE and PX domains
    Curr Top Microbiol Immunol, 282, 89-115
    DOI 10.1007/978-3-642-18805-3_4, PubMed 14594215
  5. Engelhardt M, Pfadenhauer K, Zentner J, Grimmer S, Wachenfeld-Wahl C, Heidenreich P, Loeprecht H, Wölfle KD (2004)
    [Impaired cerebral autoregulation in asymptomatic patients with carotid artery stenosis: comparison of acetazolamide-SPECT and transcranial CO(2)-dopplersonography]
    Zentralbl Chir, 129 (3), 178-82
    DOI 10.1055/s-2004-822798, PubMed 15237321
  6. Gruenberg J, Stenmark H (2004)
    The biogenesis of multivesicular endosomes
    Nat Rev Mol Cell Biol, 5 (4), 317-23
    DOI 10.1038/nrm1360, PubMed 15071556
  7. Hansen BT, Slagsvold T (2004)
    Early learning affects social dominance: interspecifically cross-fostered tits become subdominant
    Behav. Ecol., 15 (2), 262-268
    DOI 10.1093/beheco/arh010
  8. Jacobs CM, Boldingh KA, Slagsvold HH, Thoresen GH, Paulsen RE (2004)
    ERK2 prohibits apoptosis-induced subcellular translocation of orphan nuclear receptor NGFI-B/TR3
    J Biol Chem, 279 (48), 50097-101
    DOI 10.1074/jbc.M409145200, PubMed 15448159
  9. Johnson HM, Subramaniam PS, Olsnes S, Jans DA (2004)
    Trafficking and signaling pathways of nuclear localizing protein ligands and their receptors
    Bioessays, 26 (9), 993-1004
    DOI 10.1002/bies.20086, PubMed 15351969
  10. Klungsøyr HK, Skarstad K (2004)
    Positive supercoiling is generated in the presence of Escherichia coli SeqA protein
    Mol Microbiol, 54 (1), 123-31
    DOI 10.1111/j.1365-2958.2004.04239.x, PubMed 15458410
  11. Kourmanova AG, Soudarkina OJ, Olsnes S, Kozlov JV (2004)
    Cloning and characterization of the genes encoding toxic lectins in mistletoe (Viscum album L)
    Eur J Biochem, 271 (12), 2350-60
    DOI 10.1111/j.1432-1033.2004.04153.x, PubMed 15182350
  12. Kowanetz K, Crosetto N, Haglund K, Schmidt MHH, Heldin CH, Dikic I (2004)
    Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases
    J Biol Chem, 279 (31), 32786-95
    DOI 10.1074/jbc.M403759200, PubMed 15159412
  13. Lauvrak SU, Torgersen ML, Sandvig K (2004)
    Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin
    J Cell Sci, 117 (Pt 11), 2321-31
    DOI 10.1242/jcs.01081, PubMed 15126632
  14. Loog M, Oskolkov N, O'Farrell F, Ek P, Järv J (2004)
    Comparison of cAMP-dependent protein kinase substrate specificity in reaction with proteins and synthetic peptides
    Biochim Biophys Acta, 1747 (2), 261-6
    DOI 10.1016/j.bbapap.2004.11.016, PubMed 15698961
  15. Masson V, de la Ballina LR, Munaut C, Wielockx B, Jost M, Maillard C, Blacher S, Bajou K, Itoh T, Itohara S, Werb Z, Libert C, Foidart JM, Noël A (2004)
    Contribution of host MMP-2 and MMP-9 to promote tumor vascularization and invasion of malignant keratinocytes
    FASEB J, 19 (2), 234-6
    DOI 10.1096/fj.04-2140fje, PubMed 15550552
  16. Molina F, Skarstad K (2004)
    Replication fork and SeqA focus distributions in Escherichia coli suggest a replication hyperstructure dependent on nucleotide metabolism
    Mol Microbiol, 52 (6), 1597-612
    DOI 10.1111/j.1365-2958.2004.04097.x, PubMed 15186411
  17. Møller MT, Samari HR, Seglen PO (2004)
    Toxin-induced tail phosphorylation of hepatocellular S6 kinase: evidence for a dual involvement of the AMP-activated protein kinase in S6 kinase regulation
    Toxicol Sci, 82 (2), 628-37
    DOI 10.1093/toxsci/kfh273, PubMed 15342961
  18. Nilssen EA, Synnes M, Tvegård T, Vebø H, Boye E, Grallert B (2004)
    Germinating fission yeast spores delay in G1 in response to UV irradiation
    BMC Cell Biol, 5 (1), 40
    DOI 10.1186/1471-2121-5-40, PubMed 15498101
  19. Olsnes S (2004)
    The history of ricin, abrin and related toxins
    Toxicon, 44 (4), 361-70
    DOI 10.1016/j.toxicon.2004.05.003, PubMed 15302520
  20. Ramírez M, Vinagre A, Ambrona J, Molina F, Maqueda M, Rebollo JE (2004)
    Genetic instability of heterozygous, hybrid, natural wine yeasts
    Appl Environ Microbiol, 70 (8), 4686-91
    DOI 10.1128/AEM.70.8.4686-4691.2004, PubMed 15294803
  21. Rusten TE, Lindmo K, Juhász G, Sass M, Seglen PO, Brech A, Stenmark H (2004)
    Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
    Dev Cell, 7 (2), 179-92
    DOI 10.1016/j.devcel.2004.07.005, PubMed 15296715
  22. Sandvig K, Spilsberg B, Lauvrak SU, Torgersen ML, Iversen TG, van Deurs B (2004)
    Pathways followed by protein toxins into cells
    Int J Med Microbiol, 293 (7-8), 483-90
    DOI 10.1078/1438-4221-00294, PubMed 15149022
  23. Sharma M, Pampinella F, Nemes C, Benharouga M, So J, Du K, Bache KG, Papsin B, Zerangue N, Stenmark H, Lukacs GL (2004)
    Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes
    J Cell Biol, 164 (6), 923-33
    DOI 10.1083/jcb.200312018, PubMed 15007060
  24. Simonsen A, Birkeland HC, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A, Stenmark H (2004)
    Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
    J Cell Sci, 117 (Pt 18), 4239-51
    DOI 10.1242/jcs.01287, PubMed 15292400
  25. Slagsvold T, Stenmark H (2004)
    The structure of an endosomal protein sorter
    Dev Cell, 7 (4), 457-8
    DOI 10.1016/j.devcel.2004.09.007, PubMed 15469831
  26. Stang E, Blystad FD, Kazazic M, Bertelsen V, Brodahl T, Raiborg C, Stenmark H, Madshus IH (2004)
    Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits
    Mol Biol Cell, 15 (8), 3591-604
    DOI 10.1091/mbc.e04-01-0041, PubMed 15194809
  27. Sørensen V, Brech A, Khnykin D, Kolpakova E, Citores L, Olsnes S (2004)
    Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus
    J Cell Sci, 117 (Pt 9), 1807-19
    DOI 10.1242/jcs.01047, PubMed 15075241
  28. Vieira OV, Harrison RE, Scott CC, Stenmark H, Alexander D, Liu J, Gruenberg J, Schreiber AD, Grinstein S (2004)
    Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria
    Mol Cell Biol, 24 (10), 4593-604
    DOI 10.1128/MCB.24.10.4593-4604.2004, PubMed 15121875
  29. Wiedłocha A, Nilsen T, Wesche J, Sørensen V, Małecki J, Marcinkowska E, Olsnes S (2004)
    Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1
    Mol Biol Cell, 16 (2), 794-810
    DOI 10.1091/mbc.e04-05-0389, PubMed 15574884
  30. Wiedłocha A, Sørensen V (2004)
    Signaling, internalization, and intracellular activity of fibroblast growth factor
    Curr Top Microbiol Immunol, 286, 45-79
    DOI 10.1007/978-3-540-69494-6_3, PubMed 15645710
  31. Zakrzewska M, Krowarsch D, Wiedlocha A, Otlewski J (2004)
    Design of fully active FGF-1 variants with increased stability
    Protein Eng Des Sel, 17 (8), 603-11
    DOI 10.1093/protein/gzh076, PubMed 15469994

Publications 2003

  1. Bach T, Krekling MA, Skarstad K (2003)
    Excess SeqA prolongs sequestration of oriC and delays nucleoid segregation and cell division
    EMBO J, 22 (2), 315-23
    DOI 10.1093/emboj/cdg020, PubMed 12514137
  2. Bache KG, Brech A, Mehlum A, Stenmark H (2003)
    Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
    J Cell Biol, 162 (3), 435-42
    DOI 10.1083/jcb.200302131, PubMed 12900395
  3. Bache KG, Raiborg C, Mehlum A, Stenmark H (2003)
    STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
    J Biol Chem, 278 (14), 12513-21
    DOI 10.1074/jbc.M210843200, PubMed 12551915
  4. Boye E, Nordström K (2003)
    Coupling the cell cycle to cell growth
    EMBO Rep, 4 (8), 757-60
    DOI 10.1038/sj.embor.embor895, PubMed 12897798
  5. Bråthe A, Gundersen LL, Nissen-Meyer J, Rise F, Spilsberg B (2003)
    Cytotoxic activity of 6-alkynyl- and 6-alkenylpurines
    Bioorg Med Chem Lett, 13 (5), 877-80
    DOI 10.1016/s0960-894x(03)00011-8, PubMed 12617912
  6. Camara JE, Skarstad K, Crooke E (2003)
    Controlled initiation of chromosomal replication in Escherichia coli requires functional Hda protein
    J Bacteriol, 185 (10), 3244-8
    DOI 10.1128/JB.185.10.3244-3248.2003, PubMed 12730188
  7. Duś D, Krawczenko A, Załecki P, Paprocka M, Wiedłocha A, Goupille C, Kieda C (2003)
    IL-7 receptor is present on human microvascular endothelial cells
    Immunol Lett, 86 (2), 163-8
    DOI 10.1016/s0165-2478(03)00018-x, PubMed 12644318
  8. Fossum S, Søreide S, Skarstad K (2003)
    Lack of SeqA focus formation, specific DNA binding and proper protein multimerization in the Escherichia coli sequestration mutant seqA2
    Mol Microbiol, 47 (3), 619-32
    DOI 10.1046/j.1365-2958.2003.t01-1-03329.x, PubMed 12535065
  9. Furre T, Furre EI, Koritzinsky M, Amellem Ø, Pettersen EO (2003)
    Lack of inverse dose-rate effect and binding of the retinoblastoma gene product in the nucleus of human cancer T-47D cells arrested in G2 by ionizing radiation
    Int J Radiat Biol, 79 (6), 413-22
    DOI 10.1080/0955300031000140784, PubMed 12963543
  10. Gillooly DJ, Raiborg C, Stenmark H (2003)
    Phosphatidylinositol 3-phosphate is found in microdomains of early endosomes
    Histochem Cell Biol, 120 (6), 445-53
    DOI 10.1007/s00418-003-0591-7, PubMed 14618335
  11. González-Gaitán M, Stenmark H (2003)
    Endocytosis and signaling: a relationship under development
    Cell, 115 (5), 513-21
    DOI 10.1016/s0092-8674(03)00932-2, PubMed 14651844
  12. Gregers TF, Nordeng TW, Birkeland HC, Sandlie I, Bakke O (2003)
    The cytoplasmic tail of invariant chain modulates antigen processing and presentation
    Eur J Immunol, 33 (2), 277-86
    DOI 10.1002/immu.200310001, PubMed 12548558
  13. Holme HK, Lindmo K, Kristiansen A, Smidsrod O (2003)
    Thermal depolymerization of alginate in the solid state
    Carbohydr. Polym., 54 (4), 431-438
    DOI 10.1016/S0144-8617(03)00134-6
  14. Iversen TG, Skretting G, van Deurs B, Sandvig K (2003)
    Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA
    Proc Natl Acad Sci U S A, 100 (9), 5175-80
    DOI 10.1073/pnas.0534231100, PubMed 12682302
  15. Kang S, Han JS, Park JH, Skarstad K, Hwang DS (2003)
    SeqA protein stimulates the relaxing and decatenating activities of topoisomerase IV
    J Biol Chem, 278 (49), 48779-85
    DOI 10.1074/jbc.M308843200, PubMed 14512422
  16. Kolpakova E, Rusten TE, Olsnes S (2003)
    Characterization and tissue expression of acidic fibroblast growth factor binding protein homologue in Drosophila melanogaster
    Gene, 310, 185-91
    DOI 10.1016/s0378-1119(03)00550-x, PubMed 12801646
  17. Kowanetz K, Szymkiewicz I, Haglund K, Kowanetz M, Husnjak K, Taylor JD, Soubeyran P, Engstrom U, Ladbury JE, Dikic I (2003)
    Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors
    J Biol Chem, 278 (41), 39735-46
    DOI 10.1074/jbc.M304541200, PubMed 12874286
  18. Llorente A, Lauvrak SU, van Deurs B, Sandvig K (2003)
    Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP)
    J Biol Chem, 278 (37), 35850-5
    DOI 10.1074/jbc.M303425200, PubMed 12847103
  19. Małecki J, Wesche J, Skjerpen CS, Wiedłocha A, Olsnes S (2003)
    Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism
    Mol Biol Cell, 15 (2), 801-14
    DOI 10.1091/mbc.e03-08-0589, PubMed 14657241
  20. Marchese A, Raiborg C, Santini F, Keen JH, Stenmark H, Benovic JL (2003)
    The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
    Dev Cell, 5 (5), 709-22
    DOI 10.1016/s1534-5807(03)00321-6, PubMed 14602072
  21. Marcinkowska E, Wiedlocha A (2003)
    Phosphatidylinositol-3 kinase-dependent activation of Akt does not correlate with either high mitogenicity or cell migration induced by FGF-1
    Anticancer Res, 23 (5A), 4071-7
    PubMed 14666721
  22. Miller C, Ingmer H, Thomsen LE, Skarstad K, Cohen SN (2003)
    DpiA binding to the replication origin of Escherichia coli plasmids and chromosomes destabilizes plasmid inheritance and induces the bacterial SOS response
    J Bacteriol, 185 (20), 6025-31
    DOI 10.1128/JB.185.20.6025-6031.2003, PubMed 14526013
  23. Morigen, Løbner-Olesen A, Skarstad K (2003)
    Titration of the Escherichia coli DnaA protein to excess datA sites causes destabilization of replication forks, delayed replication initiation and delayed cell division
    Mol Microbiol, 50 (1), 349-62
    DOI 10.1046/j.1365-2958.2003.03695.x, PubMed 14507385
  24. Mousavi SA, Brech A, Berg T, Kjeken R (2003)
    Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes
    Biochem J, 372 (Pt 3), 861-9
    DOI 10.1042/BJ20021136, PubMed 12646047
  25. Møller MT, Samari HR, Fengsrud M, Strømhaug PE, øStvold AC, Seglen PO (2003)
    Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes
    Biochem J, 373 (Pt 2), 505-13
    DOI 10.1042/BJ20030502, PubMed 12697024
  26. Nilsen T, Slagsvold T, Skjerpen CS, Brech A, Stenmark H, Olsnes S (2003)
    Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
    J Biol Chem, 279 (6), 4794-801
    DOI 10.1074/jbc.M309653200, PubMed 14604990
  27. Nilssen EA, Synnes M, Kleckner N, Grallert B, Boye E (2003)
    Intra-G1 arrest in response to UV irradiation in fission yeast
    Proc Natl Acad Sci U S A, 100 (19), 10758-63
    DOI 10.1073/pnas.1833769100, PubMed 12960401
  28. Olsnes S, Klingenberg O, Wiedłocha A (2003)
    Transport of exogenous growth factors and cytokines to the cytosol and to the nucleus
    Physiol Rev, 83 (1), 163-82
    DOI 10.1152/physrev.00021.2002, PubMed 12506129
  29. Petiot A, Faure J, Stenmark H, Gruenberg J (2003)
    PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
    J Cell Biol, 162 (6), 971-9
    DOI 10.1083/jcb.200303018, PubMed 12975344
  30. Raiborg C, Rusten TE, Stenmark H (2003)
    Protein sorting into multivesicular endosomes
    Curr Opin Cell Biol, 15 (4), 446-55
    DOI 10.1016/s0955-0674(03)00080-2, PubMed 12892785
  31. Rojo MA, Citores L, Jiménez P, Ferreras JM, Arias FJ, Méndez E, Girbés T (2003)
    Isolation and characterization of a new d-galactose-binding lectin from Sambucus racemosa L
    Protein Pept Lett, 10 (3), 287-93
    DOI 10.2174/0929866033478979, PubMed 12871149
  32. Sandvig K, van Deurs B (2003)
    Cholera toxin internalization and intoxication - Reply
    J. Cell Sci., 116 (3), 432-433
    DOI 10.1242/jcs.00200
  33. Schedlich LJ, Nilsen T, John AP, Jans DA, Baxter RC (2003)
    Phosphorylation of insulin-like growth factor binding protein-3 by deoxyribonucleic acid-dependent protein kinase reduces ligand binding and enhances nuclear accumulation
    Endocrinology, 144 (5), 1984-93
    DOI 10.1210/en.2002-220798, PubMed 12697706
  34. Skarstad K, Boye E, Fanning E (2003)
    Circles in the sand
    EMBO Rep, 4 (7), 661-5
    DOI 10.1038/sj.embor.embor888, PubMed 12835752
  35. Skarstad K, Løbner-Olesen A (2003)
    Stable co-existence of separate replicons in Escherichia coli is dependent on once-per-cell-cycle initiation
    EMBO J, 22 (1), 140-50
    DOI 10.1093/emboj/cdg003, PubMed 12505992
  36. Slominska M, Wahl A, Wegrzyn G, Skarstad K (2003)
    Degradation of mutant initiator protein DnaA204 by proteases ClpP, ClpQ and Lon is prevented when DNA is SeqA-free
    Biochem J, 370 (Pt 3), 867-71
    DOI 10.1042/BJ20021161, PubMed 12479794
  37. Spilsberg B, Van Meer G, Sandvig K (2003)
    Role of lipids in the retrograde pathway of ricin intoxication
    Traffic, 4 (8), 544-52
    DOI 10.1034/j.1600-0854.2003.00111.x, PubMed 12839497
  38. Storen T, Simonsen A, Royset AK, Lokberg OJ, Svaasand LO, Lindmo T (2003)
    Time resolved spectroscopic optical coherence tomography for diffusion measurements
    P SOC PHOTO-OPT INS, 4956, 197-204
    DOI 10.1117/12.477645
  39. van Deurs B, Roepstorff K, Hommelgaard AM, Sandvig K (2003)
    Caveolae: anchored, multifunctional platforms in the lipid ocean
    Trends Cell Biol, 13 (2), 92-100
    DOI 10.1016/s0962-8924(02)00039-9, PubMed 12559760
  40. Ying M, Grimmer S, Iversen TG, Van Deurs B, Sandvig K (2003)
    Cholesterol loading induces a block in the exit of VSVG from the TGN
    Traffic, 4 (11), 772-84
    DOI 10.1034/j.1600-0854.2003.00134.x, PubMed 14617359

Publications 2002

  1. Andresen G, Gundersen LL, Nissen-Meyer J, Rise F, Spilsberg B (2002)
    Cytotoxic and antibacterial activity of 2-oxopurine derivatives
    Bioorg Med Chem Lett, 12 (4), 567-9
    DOI 10.1016/s0960-894x(01)00803-4, PubMed 11844673
  2. Bache KG, Raiborg C, Mehlum A, Madshus IH, Stenmark H (2002)
    Phosphorylation of Hrs downstream of the epidermal growth factor receptor
    Eur J Biochem, 269 (16), 3881-7
    DOI 10.1046/j.1432-1033.2002.03046.x, PubMed 12180964
  3. Birkeli KA, Llorente A, Torgersen ML, Keryer G, Taskén K, Sandvig K (2002)
    Endosome-to-Golgi transport is regulated by protein kinase A type II alpha
    J Biol Chem, 278 (3), 1991-7
    DOI 10.1074/jbc.M209982200, PubMed 12419802
  4. Braathen R, Sorensen V, Brandtzaeg P, Sandlie I, Johansen FE (2002)
    The carboxyl-terminal domains of IgA and IgM direct isotype-specific polymerization and interaction with the polymeric immunoglobulin receptor
    J Biol Chem, 277 (45), 42755-62
    DOI 10.1074/jbc.M205502200, PubMed 12213814
  5. Grimmer S, van Deurs B, Sandvig K (2002)
    Membrane ruffling and macropinocytosis in A431 cells require cholesterol
    J Cell Sci, 115 (Pt 14), 2953-62
    DOI 10.1242/jcs.115.14.2953, PubMed 12082155
  6. Gundersen LL, Nissen-Meyer J, Spilsberg B (2002)
    Synthesis and antimycobacterial activity of 6-arylpurines: the requirements for the N-9 substituent in active antimycobacterial purines
    J Med Chem, 45 (6), 1383-6
    DOI 10.1021/jm0110284, PubMed 11882008
  7. Kauppi M, Simonsen A, Bremnes B, Vieira A, Callaghan J, Stenmark H, Olkkonen VM (2002)
    The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
    J Cell Sci, 115 (Pt 5), 899-911
    DOI 10.1242/jcs.115.5.899, PubMed 11870209
  8. Lagaudrière-Gesbert C, Newmyer SL, Gregers TF, Bakke O, Ploegh HL (2002)
    Uncoating ATPase Hsc70 is recruited by invariant chain and controls the size of endocytic compartments
    Proc Natl Acad Sci U S A, 99 (3), 1515-20
    DOI 10.1073/pnas.042688099, PubMed 11818572
  9. Larsen AK, Møller MT, Blankson H, Samari HR, Holden L, Seglen PO (2002)
    Naringin-sensitive phosphorylation of plectin, a cytoskeletal cross-linking protein, in isolated rat hepatocytes
    J Biol Chem, 277 (38), 34826-35
    DOI 10.1074/jbc.M205028200, PubMed 12095991
  10. Lauvrak SU, Llorente A, Iversen TG, Sandvig K (2002)
    Selective regulation of the Rab9-independent transport of ricin to the Golgi apparatus by calcium
    J Cell Sci, 115 (Pt 17), 3449-56
    DOI 10.1242/jcs.115.17.3449, PubMed 12154075
  11. Luk'ianov EV, Viedlokha A, Kuianskaia DV, Olsnes S, Kozlov IuV (2002)
    [A short form of the heparin-binding EGF-like growth factor with a changed EGF domain]
    Mol Biol (Mosk), 36 (1), 76-83
    PubMed 11862716
  12. Luk'yanov EV,