Publications

Publications 2024

  1. Brugger M, Lauri A, Zhen Y, Gramegna LL, Zott B, Sekulić N, Fasano G, Kopajtich R, Cordeddu V, Radio FC, Mancini C, Pizzi S, Paradisi G, Zanni G, Vasco G, Carrozzo R, Palombo F, Tonon C, Lodi R, La Morgia C, Arelin M, Blechschmidt C, Finck T, Sørensen V, Kreiser K et al. (2024)
    Bi-allelic variants in SNF8 cause a disease spectrum ranging from severe developmental and epileptic encephalopathy to syndromic optic atrophy
    Am J Hum Genet, 111 (3), 594-613
    DOI 10.1016/j.ajhg.2024.02.005, PubMed 38423010
  2. Casey NP, Kleinmanns K, Forcados C, Gelebart PF, Joaquina S, Lode M, Benard E, Kaveh F, Caulier B, Helgestad Gjerde C, García de Jalón E, Warren DJ, Lindemann K, Rokkones E, Davidson B, Myhre MR, Kvalheim G, Bjørge L, McCormack E, Inderberg EM, Wälchli S (2024)
    Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16
    J Immunother Cancer, 12 (4)
    DOI 10.1136/jitc-2023-008179, PubMed 38604812
  3. Caulier B, Joaquina S, Gelebart P, Dowling TH, Kaveh F, Thomas M, Tandaric L, Wernhoff P, Katyayini NU, Wogsland C, Gjerstad ME, Fløisand Y, Kvalheim G, Marr C, Kobold S, Enserink JM, Gjertsen BT, McCormack E, Inderberg EM, Wälchli S (2024)
    CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
    Cell Rep Med, 5 (6), 101572
    DOI 10.1016/j.xcrm.2024.101572, PubMed 38754420
  4. Corrales J, Ramos-Alonso L, González-Sabín J, Ríos-Lombardía N, Trevijano-Contador N, Engen Berg H, Sved Skottvoll F, Moris F, Zaragoza O, Chymkowitch P, Garcia I, Enserink JM (2024)
    Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole
    Microbiol Spectr, 12 (2), e0259423
    DOI 10.1128/spectrum.02594-23, PubMed 38230926
  5. Duran J, Salinas JE, Wheaton RP, Poolsup S, Allers L, Rosas-Lemus M, Chen L, Cheng Q, Pu J, Salemi M, Phinney B, Ivanov P, Lystad AH, Bhaskar K, Rajaiya J, Perkins DJ, Jia J (2024)
    Calcium signaling from damaged lysosomes induces cytoprotective stress granules
    EMBO J, 43 (24), 6410-6443
    DOI 10.1038/s44318-024-00292-1, PubMed 39533058
  6. Fuentes-Martín R, Ayuda-Durán P, Hanes R, Gallego-Yerga L, Wolterinck L, Enserink JM, Álvarez R, Peláez R (2024)
    Promising anti-proliferative indolic benzenesulfonamides alter mechanisms with sulfonamide nitrogen substituents
    Eur J Med Chem, 275, 116617
    DOI 10.1016/j.ejmech.2024.116617, PubMed 38959729
  7. Hamid MHBA, Cespedes PF, Jin C, Chen JL, Gileadi U, Antoun E, Liang Z, Gao F, Teague R, Manoharan N, Maldonado-Perez D, Khalid-Alham N, Cerundolo L, Ciaoca R, Hester SS, Pinto-Fernández A, Draganov SD, Vendrell I, Liu G, Yao X, Kvalvaag A, Dominey-Foy DCC, Nanayakkara C, Kanellakis N, Chen YL et al. (2024)
    Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity
    Nat Immunol, 25 (5), 834-846
    DOI 10.1038/s41590-024-01802-3, PubMed 38561495
  8. Klavina A, Ceseiko R, Campa M, Jermolenko GF, Eglitis K, Llorente A, Linē A (2024)
    The Effect of High-Intensity Interval Training on Quality of Life and Incidence of Chemotherapy Side Effects in Women With Breast Cancer
    Integr Cancer Ther, 23, 15347354241297385
    DOI 10.1177/15347354241297385, PubMed 39548802
  9. Kvalvaag A, Dustin ML (2024)
    Clathrin controls bidirectional communication between T cells and antigen presenting cells
    Bioessays, 46 (4), e2300230
    DOI 10.1002/bies.202300230, PubMed 38412391
  10. Lamsal A, Andersen SB, Johansson I, Desgarnier MD, Wolowczyk C, Engedal N, Vietri M, Bjørkøy G, Giambelluca MS, Pettersen K (2024)
    Elucidating the power of arginine restriction: taming type I interferon response in breast cancer via selective autophagy
    Cell Commun Signal, 22 (1), 481
    DOI 10.1186/s12964-024-01858-6, PubMed 39380098
  11. Llorente A, Brokāne A, Mlynska A, Puurand M, Sagini K, Folkmane S, Hjorth M, Martin-Gracia B, Romero S, Skorinkina D, Čampa M, Cešeiko R, Romanchikova N, Kļaviņa A, Käämbre T, Linē A (2024)
    From sweat to hope: The role of exercise-induced extracellular vesicles in cancer prevention and treatment
    J Extracell Vesicles, 13 (8), e12500
    DOI 10.1002/jev2.12500, PubMed 39183543
  12. Nähse V, Stenmark H, Schink KO (2024)
    Omegasomes control formation, expansion, and closure of autophagosomes
    Bioessays, 46 (6), e2400038
    DOI 10.1002/bies.202400038, PubMed 38724256
  13. Pankiv S, Dahl AK, Aas A, Andersen RL, Brech A, Holland P, Singh S, Bindesbøll C, Simonsen A (2024)
    BEACH domain proteins function as cargo-sorting adaptors in secretory and endocytic pathways
    J Cell Biol, 223 (12)
    DOI 10.1083/jcb.202408173, PubMed 39514288
  14. Philips EA, Liu J, Kvalvaag A, Mørch AM, Tocheva AS, Ng C, Liang H, Ahearn IM, Pan R, Luo CC, Leithner A, Qin Z, Zhou Y, Garcia-España A, Mor A, Littman DR, Dustin ML, Wang J, Kong XP (2024)
    Transmembrane domain-driven PD-1 dimers mediate T cell inhibition
    Sci Immunol, 9 (93), eade6256
    DOI 10.1126/sciimmunol.ade6256, PubMed 38457513
  15. Radulovic M, Stenmark H (2024)
    Lysophagy prevents neurotoxic aggregate transmission
    Proc Natl Acad Sci U S A, 121 (3), e2321181121
    DOI 10.1073/pnas.2321181121, PubMed 38190545
  16. Sandvig K, Iversen TG, Skotland T (2024)
    Entry of nanoparticles into cells and tissues: status and challenges
    Beilstein J Nanotechnol, 15, 1017-1029
    DOI 10.3762/bjnano.15.83, PubMed 39161463
  17. Skotland T, Ekroos K, McDonald J, Ahrends R, Liebisch G, Sandvig K (2024)
    Pitfalls in lipid mass spectrometry of mammalian samples - a brief guide for biologists
    Nat Rev Mol Cell Biol, 25 (10), 759-760
    DOI 10.1038/s41580-024-00758-4, PubMed 38951702
  18. Teles-Reis J, Jain A, Liu D, Khezri R, Micheli S, Gomez AA, Dillard C, Rusten TE (2024)
    EyaHOST, a modular genetic system for investigation of intercellular and tumor-host interactions in Drosophila melanogaster
    bioRxiv
    DOI 10.1101/2024.09.06.611647, PubMed 39314415
  19. Theriot JA, Simonsen A, Tolić I, Leonetti MD, Mayor S, Bassereau P, Paluch EK, Han J, Covert MW, Mizushima N, Reck-Peterson S, Strasser A, Cheeseman I (2024)
    Cell biology is…
    Cell, 187 (2), 219-224
    DOI 10.1016/j.cell.2023.12.020, PubMed 38242078
  20. Totland MZ, Knudsen LM, Rasmussen NL, Omori Y, Sørensen V, Elster VCW, Stenersen JM, Larsen M, Jensen CL, Zickfeldt Lade AA, Bruusgaard E, Basing S, Kryeziu K, Brech A, Aasen T, Lothe RA, Leithe E (2024)
    The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation
    Cell Mol Life Sci, 81 (1), 171
    DOI 10.1007/s00018-024-05165-8, PubMed 38597989
  21. Valsalakumari R, Pandya AD, Prasmickaite L, Kvalvaag A, Myrann AG, Åslund AKO, Kjos MS, Fontecha-Cuenca C, Haroon HB, Ribeiro ARS, Horejs-Hoeck J, Moghimi SM, Mørch Ý, Skotland T, Sandvig K, Mælandsmo GM, Iversen TG (2024)
    Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
    Int J Nanomedicine, 19, 3009-3029
    DOI 10.2147/IJN.S450283, PubMed 38562610
  22. Wang HL, Siow R, Schmauck-Medina T, Zhang J, Sandset PM, Filshie C, Lund Ø, Partridge L, Bergersen LH, Juel Rasmussen L, Palikaras K, Sotiropoulos I, Storm-Mathisen J, Rubinsztein DC, Spillantini MG, De Zeeuw CI, Watne LO, Vyhnalek M, Veverova K, Liang KX, Tavernarakis N, Bohr VA, Yokote K, Saarela J, Nilsen H et al. (2024)
    Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies
    J Gerontol A Biol Sci Med Sci, 79 (4)
    DOI 10.1093/gerona/glae029, PubMed 38289789
  23. Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S et al. (2024)
    Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
    J Extracell Vesicles, 13 (2), e12404
    DOI 10.1002/jev2.12404, PubMed 38326288
  24. Wenzel EM, Pedersen NM, Elfmark LA, Wang L, Kjos I, Stang E, Malerød L, Brech A, Stenmark H, Raiborg C (2024)
    Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
    Nat Commun, 15 (1), 1277
    DOI 10.1038/s41467-024-45558-8, PubMed 38341434
  25. Wu C, Gunnarsson EB, Myklebust EM, Köhn-Luque A, Tadele DS, Enserink JM, Frigessi A, Foo J, Leder K (2024)
    Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data
    PLoS Comput Biol, 20 (3), e1011888
    DOI 10.1371/journal.pcbi.1011888, PubMed 38446830
  26. Zhen Y, Stenmark H (2024)
    A dual-purpose fusion complex in autophagy
    Cell Res, 34 (3), 183-184
    DOI 10.1038/s41422-023-00925-w, PubMed 38228880
  27. Zhen Y, Stenmark H (2024)
    Exosome regulation by Rubicon in ageing
    Nat Cell Biol, 26 (9), 1380-1381
    DOI 10.1038/s41556-024-01482-z, PubMed 39174741

Publications 2023

  1. Al Outa A, Hicks S, Thambawita V, Andresen S, Enserink JM, Halvorsen P, Riegler MA, Knævelsrud H (2023)
    CELLULAR, A Cell Autophagy Imaging Dataset
    Sci Data, 10 (1), 806
    DOI 10.1038/s41597-023-02687-x, PubMed 37973836
  2. Andersen AN, Brodersen AM, Ayuda-Durán P, Piechaczyk L, Tadele DS, Baken L, Fredriksen J, Stoksflod M, Lenartova A, Fløisand Y, Skånland SS, Enserink JM (2023)
    Clinical forecasting of acute myeloid leukemia using ex vivo drug-sensitivity profiling
    Cell Rep Methods, 3 (12), 100654
    DOI 10.1016/j.crmeth.2023.100654, PubMed 38065095
  3. Ayuda-Durán P, Hermansen JU, Giliberto M, Yin Y, Hanes R, Gordon S, Kuusanmäki H, Brodersen AM, Andersen AN, Taskén K, Wennerberg K, Enserink JM, Skånland SS (2023)
    Standardized assays to monitor drug sensitivity in hematologic cancers
    Cell Death Discov, 9 (1), 435
    DOI 10.1038/s41420-023-01722-5, PubMed 38040674
  4. Bajo-Santos C, Brokāne A, Zayakin P, Endzeliņš E, Soboļevska K, Belovs A, Jansons J, Sperga M, Llorente A, Radoviča-Spalviņa I, Lietuvietis V, Linē A (2023)
    Plasma and urinary extracellular vesicles as a source of RNA biomarkers for prostate cancer in liquid biopsies
    Front Mol Biosci, 10, 980433
    DOI 10.3389/fmolb.2023.980433, PubMed 36818049
  5. Capera J, Jainarayanan A, Navarro-Pérez M, Valvo S, Demetriou P, Depoil D, Estadella I, Kvalvaag A, Felce JH, Felipe A, Dustin ML (2023)
    Dynamics and spatial organization of Kv1.3 at the immunological synapse of human CD4+ T cells
    Biophys J, 123 (15), 2271-2281
    DOI 10.1016/j.bpj.2023.08.011, PubMed 37596785
  6. Casey NP, Klee CH, Fåne A, Caulier B, Graczyk-Jarzynka A, Krawczyk M, Fidyt K, Josefsson SE, Köksal H, Dillard P, Patkowska E, Firczuk M, Smeland EB, Winiarska M, Myklebust JH, Inderberg EM, Wälchli S (2023)
    Efficient chimeric antigen receptor targeting of a central epitope of CD22
    J Biol Chem, 299 (7), 104883
    DOI 10.1016/j.jbc.2023.104883, PubMed 37269947
  7. Chen Y, He L, Ianevski A, Ayuda-Durán P, Potdar S, Saarela J, Miettinen JJ, Kytölä S, Miettinen S, Manninen M, Heckman CA, Enserink JM, Wennerberg K, Aittokallio T (2023)
    Robust scoring of selective drug responses for patient-tailored therapy selection
    Nat Protoc, 19 (1), 60-82
    DOI 10.1038/s41596-023-00903-x, PubMed 37996540
  8. Clement D, Szabo EK, Krokeide SZ, Wiiger MT, Vincenti M, Palacios D, Chang YT, Grimm C, Patel S, Stenmark H, Brech A, Majhi RK, Malmberg KJ (2023)
    The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk
    J Immunol, 211 (9), 1348-1358
    DOI 10.4049/jimmunol.2300406, PubMed 37737664
  9. Davies EM, Mitchell CA, Stenmark HA (2023)
    Phosphoinositides in New Spaces
    Cold Spring Harb Perspect Biol, 15 (9)
    DOI 10.1101/cshperspect.a041406, PubMed 37463718
  10. Elfmark LA, Wenzel EM, Wang L, Pedersen NM, Stenmark H, Raiborg C (2023)
    Protrudin-mediated ER-endosome contact sites promote phagocytosis
    Cell Mol Life Sci, 80 (8), 216
    DOI 10.1007/s00018-023-04862-0, PubMed 37468729
  11. Hanes R, Ayuda-Durán P, Rønneberg L, Nakken S, Hovig E, Zucknick M, Enserink JM (2023)
    screenwerk: a modular tool for the design and analysis of drug combination screens
    Bioinformatics, 39 (1)
    DOI 10.1093/bioinformatics/btac840, PubMed 36573326
  12. Hessvik NP, Sagini K, Romero S, Ramirez-Garrastacho M, Rodriguez M, Tutturen AEV, Kvalvaag A, Stang E, Brech A, Sandvig K, Llorente A (2023)
    siRNA screening reveals that SNAP29 contributes to exosome release
    Cell Mol Life Sci, 80 (7), 177
    DOI 10.1007/s00018-023-04822-8, PubMed 37285022
  13. Holme B, Bjørnerud B, Pedersen NM, de la Ballina LR, Wesche J, Haugsten EM (2023)
    Automated tracking of cell migration in phase contrast images with CellTraxx
    Sci Rep, 13 (1), 22982
    DOI 10.1038/s41598-023-50227-9, PubMed 38151514
  14. Joaquina S, Forcados C, Caulier B, Inderberg EM, Wälchli S (2023)
    Determination of CAR T cell metabolism in an optimized protocol
    Front Bioeng Biotechnol, 11, 1207576
    DOI 10.3389/fbioe.2023.1207576, PubMed 37409169
  15. Johannessen JA, Formica M, Haukeland ALC, Bråthen NR, Al Outa A, Aarsund M, Therrien M, Enserink JM, Knævelsrud H (2023)
    The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae
    iScience, 26 (10), 107726
    DOI 10.1016/j.isci.2023.107726, PubMed 37720104
  16. Kaur N, Carlsson SR, Lystad AH (2023)
    The separate axes of TECPR1 and ATG16L1 in CASM
    Autophagy, 20 (1), 214-215
    DOI 10.1080/15548627.2023.2255462, PubMed 37676042
  17. Kaur N, de la Ballina LR, Haukaas HS, Torgersen ML, Radulovic M, Munson MJ, Sabirsh A, Stenmark H, Simonsen A, Carlsson SR, Lystad AH (2023)
    TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
    EMBO J, 42 (17), e113105
    DOI 10.15252/embj.2022113105, PubMed 37409525
  18. Kvalvaag A, Valvo S, Céspedes PF, Saliba DG, Kurz E, Korobchevskaya K, Dustin ML (2023)
    Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse
    Proc Natl Acad Sci U S A, 120 (6), e2211368120
    DOI 10.1073/pnas.2211368120, PubMed 36730202
  19. Köhn-Luque A, Myklebust EM, Tadele DS, Giliberto M, Schmiester L, Noory J, Harivel E, Arsenteva P, Mumenthaler SM, Schjesvold F, Taskén K, Enserink JM, Leder K, Frigessi A, Foo J (2023)
    Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data
    Cell Rep Methods, 3 (3), 100417
    DOI 10.1016/j.crmeth.2023.100417, PubMed 37056380
  20. Lampart A, Krowarsch D, Biadun M, Sorensen V, Szymczyk J, Sluzalska K, Wiedlocha A, Otlewski J, Zakrzewska M (2023)
    Intracellular FGF1 protects cells from apoptosis through direct interaction with p53
    Cell Mol Life Sci, 80 (10), 311
    DOI 10.1007/s00018-023-04964-9, PubMed 37783936
  21. Lamsal A, Andersen SB, Johansson I, Vietri M, Bokil AA, Kurganovs NJ, Rylander F, Bjørkøy G, Pettersen K, Giambelluca MS (2023)
    Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer
    Cell Commun Signal, 21 (1), 50
    DOI 10.1186/s12964-023-01062-y, PubMed 36882786
  22. Margadant F, Almsherqi Z, Xu X, Deng Y (2023)
    Optical Properties and Interference Effects of the Lens Mitochondrion
    Membranes (Basel), 13 (6)
    DOI 10.3390/membranes13060610, PubMed 37367815
  23. Migliano SM, Schultz SW, Wenzel EM, Takáts S, Liu D, Mørk S, Tan KW, Rusten TE, Raiborg C, Stenmark H (2023)
    Removal of hypersignaling endosomes by simaphagy
    Autophagy, 20 (4), 769-791
    DOI 10.1080/15548627.2023.2267958, PubMed 37840274
  24. Nunzi E, Mezzasoma L, Bellezza I, Zelante T, Orvietani P, Coata G, Giardina I, Sagini K, Manni G, Di Michele A, Gargaro M, Talesa VN, Di Renzo GC, Fallarino F, Romani R (2023)
    Microbiota-Associated HAF-EVs Regulate Monocytes by Triggering or Inhibiting Inflammasome Activation
    Int J Mol Sci, 24 (3)
    DOI 10.3390/ijms24032527, PubMed 36768851
  25. Nähse V, Raiborg C, Tan KW, Mørk S, Torgersen ML, Wenzel EM, Nager M, Salo VT, Johansen T, Ikonen E, Schink KO, Stenmark H (2023)
    ATPase activity of DFCP1 controls selective autophagy
    Nat Commun, 14 (1), 4051
    DOI 10.1038/s41467-023-39641-9, PubMed 37422481
  26. Nähse V, Schink KO, Stenmark H (2023)
    ATPase-regulated autophagosome biogenesis
    Autophagy, 20 (1), 218-219
    DOI 10.1080/15548627.2023.2255967, PubMed 37722386
  27. Perdreau-Dahl H, Lipsett DB, Frisk M, Kermani F, Carlson CR, Brech A, Shen X, Bergan-Dahl A, Hou Y, Tuomainen T, Tavi P, Jones PP, Lunde M, Wasserstrom JA, Laporte J, Ullrich ND, Christensen G, Morth JP, Louch WE (2023)
    BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes
    Circ Res, 132 (11), e188-e205
    DOI 10.1161/CIRCRESAHA.122.321732, PubMed 37139790
  28. Pust S, Brech A, Wegner CS, Stenmark H, Haglund K (2023)
    Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis
    Cell Mol Life Sci, 80 (8), 235
    DOI 10.1007/s00018-023-04864-y, PubMed 37523003
  29. Ramos-Alonso L, Holland P, Le Gras S, Zhao X, Jost B, Bjørås M, Barral Y, Enserink JM, Chymkowitch P (2023)
    Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
    Proc Natl Acad Sci U S A, 120 (4), e2210593120
    DOI 10.1073/pnas.2210593120, PubMed 36656860
  30. Sagini K, Urbanelli L, Buratta S, Emiliani C, Llorente A (2023)
    Lipid Biomarkers in Liquid Biopsies: Novel Opportunities for Cancer Diagnosis
    Pharmaceutics, 15 (2)
    DOI 10.3390/pharmaceutics15020437, PubMed 36839759
  31. Sandoz PA, Kuhnigk K, Szabo EK, Thunberg S, Erikson E, Sandström N, Verron Q, Brech A, Watzl C, Wagner AK, Alici E, Malmberg KJ, Uhlin M, Önfelt B (2023)
    Modulation of lytic molecules restrain serial killing in γδ T lymphocytes
    Nat Commun, 14 (1), 6035
    DOI 10.1038/s41467-023-41634-7, PubMed 37758698
  32. Sarmento MJ, Llorente A, Petan T, Khnykin D, Popa I, Nikolac Perkovic M, Konjevod M, Jaganjac M (2023)
    The expanding organelle lipidomes: current knowledge and challenges
    Cell Mol Life Sci, 80 (8), 237
    DOI 10.1007/s00018-023-04889-3, PubMed 37530856
  33. Skotland T, Llorente A, Sandvig K (2023)
    Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?
    Cold Spring Harb Perspect Biol, 15 (8)
    DOI 10.1101/cshperspect.a041415, PubMed 37277192
  34. Stonyte V, Mastrangelopoulou M, Timmer R, Lindbergsengen L, Vietri M, Campsteijn C, Grallert B (2023)
    The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity
    EMBO Rep, 24 (8), e56100
    DOI 10.15252/embr.202256100, PubMed 37291955
  35. Tislevoll BS, Hellesøy M, Fagerholt OHE, Gullaksen SE, Srivastava A, Birkeland E, Kleftogiannis D, Ayuda-Durán P, Piechaczyk L, Tadele DS, Skavland J, Baliakas P, Hovland R, Andresen V, Seternes OM, Tvedt THA, Aghaeepour N, Gavasso S, Porkka K, Jonassen I, Fløisand Y, Enserink J, Blaser N, Gjertsen BT (2023)
    Early response evaluation by single cell signaling profiling in acute myeloid leukemia
    Nat Commun, 14 (1), 115
    DOI 10.1038/s41467-022-35624-4, PubMed 36611026
  36. Tislevoll BS, Hellesøy M, Fagerholt OHE, Gullaksen SE, Srivastava A, Birkeland E, Kleftogiannis D, Ayuda-Durán P, Piechaczyk L, Tadele DS, Skavland J, Baliakas P, Hovland R, Andresen V, Seternes OM, Tvedt THA, Aghaeepour N, Gavasso S, Porkka K, Jonassen I, Fløisand Y, Enserink J, Blaser N, Gjertsen BT (2023)
    Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia
    Nat Commun, 14 (1), 1767
    DOI 10.1038/s41467-023-37488-8, PubMed 36997540
  37. Totland MZ, Omori Y, Sørensen V, Kryeziu K, Aasen T, Brech A, Leithe E (2023)
    Endocytic trafficking of connexins in cancer pathogenesis
    Biochim Biophys Acta Mol Basis Dis, 1869 (7), 166812
    DOI 10.1016/j.bbadis.2023.166812, PubMed 37454772
  38. van den Berg CM, Volkov VA, Schnorrenberg S, Huang Z, Stecker KE, Grigoriev I, Gilani S, Frikstad KM, Patzke S, Zimmermann T, Dogterom M, Akhmanova A (2023)
    CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side
    J Cell Biol, 222 (4)
    DOI 10.1083/jcb.202208062, PubMed 36752787
  39. van Royen ME, Soekmadji C, Grange C, Webber JP, Tertel T, Droste M, Buescher A, Giebel B, Jenster GW, Llorente A, Blijdorp CJ, Burger D, Erdbrügger U, Martens-Uzunova ES (2023)
    The quick reference card "Storage of urinary EVs" - A practical guideline tool for research and clinical laboratories
    J Extracell Vesicles, 12 (3), e12286
    DOI 10.1002/jev2.12286, PubMed 36916183
  40. Wu C, Gunnarsson EB, Myklebust EM, Köhn-Luque A, Tadele DS, Enserink JM, Frigessi A, Foo J, Leder K (2023)
    Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data
    ArXiv
    PubMed 37396610
  41. Yao Y, Sun H, Wurihan, Gegeheng, Gezi, Skarstad K, Fan L, Morigen (2023)
    A DnaA‐dependent riboswitch for transcription attenuation of the his operon
    mLife, 2 (2), 126-140
    DOI 10.1002/mlf2.12075, PublikaID 479
  42. Yao Y, Sun H, Wurihan, Gegeheng, Gezi, Skarstad K, Fan L, Morigen (2023)
    A DnaA-dependent riboswitch for transcription attenuation of the his operon
    mLife, 2 (2), 126-140
    DOI 10.1002/mlf2.12075, PubMed 38817620
  43. Zhen Y, Stenmark H (2023)
    Autophagosome Biogenesis
    Cells, 12 (4)
    DOI 10.3390/cells12040668, PubMed 36831335
  44. Zhen Y, Stenmark H (2023)
    A phosphoinositide kinase triggers migrasome formation
    Cell Res, 33 (8), 577-578
    DOI 10.1038/s41422-023-00822-2, PubMed 37165066

Publications 2022

  1. Arora A, Kivelä AM, Wang L, Minkeviciene R, Taskinen JH, Zhang B, Koponen A, Sun J, Shirane M, Zhou Y, Hotulainen P, Raiborg C, Olkkonen VM (2022)
    Protrudin regulates FAK activation, endothelial cell migration and angiogenesis
    Cell Mol Life Sci, 79 (4), 220
    DOI 10.1007/s00018-022-04251-z, PubMed 35368213
  2. Blijdorp CJ, Burger D, Llorente A, Martens-Uzunova ES, Erdbrügger U (2022)
    Extracellular Vesicles as Novel Players in Kidney Disease
    J Am Soc Nephrol, 33 (3), 467-471
    DOI 10.1681/ASN.2021091232, PubMed 35131841
  3. Bousquet PA, Manna D, Sandvik JA, Arntzen MØ, Moreno E, Sandvig K, Krengel U (2022)
    SILAC-based quantitative proteomics and microscopy analysis of cancer cells treated with the N-glycolyl GM3-specific anti-tumor antibody 14F7
    Front Immunol, 13, 994790
    DOI 10.3389/fimmu.2022.994790, PubMed 36439103
  4. Bril'kov MS, Dobrovolska O, Ødegård-Fougner Ø, Turcu DC, Strømland Ø, Underhaug J, Aasland R, Halskau Ø (2022)
    Binding Specificity of ASHH2 CW Domain Toward H3K4me1 Ligand Is Coupled to Its Structural Stability Through Its α1-Helix
    Front Mol Biosci, 9, 763750
    DOI 10.3389/fmolb.2022.763750, PubMed 35495628
  5. Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J et al. (2022)
    Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
    Ann N Y Acad Sci, 1510 (1), 79-99
    DOI 10.1111/nyas.14745, PubMed 35000205
  6. Charsou C, Ng MYW, Simonsen A (2022)
    Regulation of autophagosome biogenesis and mitochondrial bioenergetics by the cholesterol transport protein GRAMD1C
    Autophagy, 19 (7), 2159-2161
    DOI 10.1080/15548627.2022.2155020, PubMed 36469687
  7. Doncheva AI, Romero S, Ramirez-Garrastacho M, Lee S, Kolnes KJ, Tangen DS, Olsen T, Drevon CA, Llorente A, Dalen KT, Hjorth M (2022)
    Extracellular vesicles and microRNAs are altered in response to exercise, insulin sensitivity and overweight
    Acta Physiol (Oxf), 236 (4), e13862
    DOI 10.1111/apha.13862, PubMed 36377504
  8. Du H, Yang F, Yao C, Lv W, Peng H, Stanciu SG, Stenmark HA, Song YM, Jiang B, Wu A (2022)
    "Double-punch" strategy against triple-negative breast cancer via a synergistic therapy of magneto-mechanical force enhancing NIR-II hypothermal ablation
    Biomaterials, 291, 121868
    DOI 10.1016/j.biomaterials.2022.121868, PubMed 36332286
  9. Du H, Yang F, Yao C, Zhong Z, Jiang P, Stanciu SG, Peng H, Hu J, Jiang B, Li Z, Lv W, Zheng F, Stenmark HA, Wu A (2022)
    Multifunctional Modulation of High-Performance Znx Fe3-x O4 Nanoparticles by Precisely Tuning the Zinc Doping Content
    Small, 18 (42), e2201669
    DOI 10.1002/smll.202201669, PubMed 36101918
  10. Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML (2022)
    Measuring Autophagic Cargo Flux with Keima-Based Probes
    Methods Mol Biol, 2445, 99-115
    DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988
  11. Enserink JM (2022)
    The SUMO stress response in transcriptional regulation: Causal relationships or secondary bystander effects?
    Bioessays, 44 (7), e2200065
    DOI 10.1002/bies.202200065, PubMed 35655365
  12. Enserink JM, Chymkowitch P (2022)
    Cell Cycle-Dependent Transcription: The Cyclin Dependent Kinase Cdk1 Is a Direct Regulator of Basal Transcription Machineries
    Int J Mol Sci, 23 (3)
    DOI 10.3390/ijms23031293, PubMed 35163213
  13. Espeland K, Kleinauskas A, Juzenas P, Brech A, Darvekar S, Vasovic V, Warloe T, Christensen E, Jahnsen J, Peng Q (2022)
    Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells
    Biomedicines, 10 (2)
    DOI 10.3390/biomedicines10020232, PubMed 35203441
  14. Fiorito E, Szybowska P, Haugsten EM, Kostas M, Øy GF, Wiedlocha A, Singh S, Nakken S, Mælandsmo GM, Fletcher JA, Meza-Zepeda LA, Wesche J (2022)
    Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
    Br J Cancer, 127 (11), 1939-1953
    DOI 10.1038/s41416-022-01973-6, PubMed 36097178
  15. Forcados C, Joaquina S, Casey NP, Caulier B, Wälchli S (2022)
    How CAR T Cells Breathe
    Cells, 11 (9)
    DOI 10.3390/cells11091454, PubMed 35563759
  16. Frikstad KM, Schink KO, Gilani S, Pedersen LB, Patzke S (2022)
    3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines
    Bio Protoc, 12 (6), e4360
    DOI 10.21769/BioProtoc.4360, PubMed 35434191
  17. Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2022)
    Corrigendum to "Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft", [Journal of Control Release, 293 (2019) 183-192]
    J Control Release, 349, 1
    DOI 10.1016/j.jconrel.2022.06.040, PubMed 35792388
  18. Ganley IG, Simonsen A (2022)
    Diversity of mitophagy pathways at a glance
    J Cell Sci, 135 (23)
    DOI 10.1242/jcs.259748, PubMed 36504076
  19. Garcia-Garcia J, Berge AKM, Overå KS, Larsen KB, Bhujabal Z, Brech A, Abudu YP, Lamark T, Johansen T, Sjøttem E (2022)
    TRIM27 is an autophagy substrate facilitating mitochondria clustering and mitophagy via phosphorylated TBK1
    FEBS J, 290 (4), 1096-1116
    DOI 10.1111/febs.16628, PubMed 36111389
  20. Holland P, Quintana EM, Khezri R, Schoborg TA, Rusten TE (2022)
    Computed tomography with segmentation and quantification of individual organs in a D. melanogaster tumor model
    Sci Rep, 12 (1), 2056
    DOI 10.1038/s41598-022-05991-5, PubMed 35136137
  21. Khezri R, Rusten TE (2022)
    Autophagy power expands: fuse those cells!
    EMBO J, 41 (12), e111424
    DOI 10.15252/embj.2022111424, PubMed 35561082
  22. Lampart A, Sluzalska KD, Czyrek A, Szerszen A, Otlewski J, Wiedlocha A, Zakrzewska M (2022)
    Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells
    Cells, 11 (3)
    DOI 10.3390/cells11030522, PubMed 35159330
  23. Lobert VH, Skardal ML, Malerød L, Simensen JE, Algra HA, Andersen AN, Fleischer T, Enserink HA, Liestøl K, Heath JK, Rusten TE, Stenmark HA (2022)
    PHLPP1 regulates CFTR activity and lumen expansion through AMPK
    Development, 149 (20)
    DOI 10.1242/dev.200955, PubMed 35997536
  24. Mateus D, Wiedlocha A (2022)
    FGF-FGFR signaling promotes the development of invasive cervical cancer
    FEBS J, 289 (12), 3419-3421
    DOI 10.1111/febs.16384, PubMed 35146913
  25. Mehto S, Jena KK, Yadav R, Priyadarsini S, Samal P, Krishna S, Dhar K, Jain A, Chauhan NR, Murmu KC, Bal R, Sahu R, Jaiswal P, Sahoo BS, Patnaik S, Kufer TA, Rusten TE, Chauhan S, Prasad P, Chauhan S (2022)
    Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection
    EMBO J, 41 (23), e111289
    DOI 10.15252/embj.2022111289, PubMed 36221902
  26. Mezzasoma L, Bellezza I, Orvietani P, Manni G, Gargaro M, Sagini K, Llorente A, Scarpelli P, Pascucci L, Cellini B, Talesa VN, Fallarino F, Romani R (2022)
    Amniotic fluid stem cell-derived extracellular vesicles are independent metabolic units capable of modulating inflammasome activation in THP-1 cells
    FASEB J, 36 (4), e22218
    DOI 10.1096/fj.202101657R, PubMed 35218567
  27. Migliano SM, Stenmark H (2022)
    ESCRTed resistance to T cell attack
    Trends Immunol, 43 (8), 598-600
    DOI 10.1016/j.it.2022.06.007, PubMed 35810056
  28. Migliano SM, Wenzel EM, Stenmark H (2022)
    Biophysical and molecular mechanisms of ESCRT functions, and their implications for disease
    Curr Opin Cell Biol, 75, 102062
    DOI 10.1016/j.ceb.2022.01.007, PubMed 35248976
  29. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Simonsen A (2022)
    GAK and PRKCD kinases regulate basal mitophagy
    Autophagy, 18 (2), 467-469
    DOI 10.1080/15548627.2021.2015154, PubMed 35001811
  30. Ng MYW, Charsou C, Lapao A, Singh S, Trachsel-Moncho L, Schultz SW, Nakken S, Munson MJ, Simonsen A (2022)
    The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
    Nat Commun, 13 (1), 6283
    DOI 10.1038/s41467-022-33933-2, PubMed 36270994
  31. Nissen-Meyer J, Skotland T, Boye E (2022)
    Are doping tests in sports trustworthy?: Athletes suffer from insufficiently defined criteria for doping tests: Athletes suffer from insufficiently defined criteria for doping tests
    EMBO Rep, 23 (3), e54431
    DOI 10.15252/embr.202154431, PubMed 35156749
  32. Radulovic M, Wenzel EM, Gilani S, Holland LK, Lystad AH, Phuyal S, Olkkonen VM, Brech A, Jäättelä M, Maeda K, Raiborg C, Stenmark H (2022)
    Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
    EMBO J, 41 (24), e112677
    DOI 10.15252/embj.2022112677, PubMed 36408828
  33. Rahman MA, Engelsen AST, Sarowar S, Bindesbøll C, Birkeland E, Goplen D, Lotsberg ML, Knappskog S, Simonsen A, Chekenya M (2022)
    Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway
    Front Cell Dev Biol, 10, 1022191
    DOI 10.3389/fcell.2022.1022191, PubMed 36619857
  34. Ramos-Alonso L, Garcia I, Enserink JM, Chymkowitch P (2022)
    Analysis of the pheromone signaling pathway by RT-qPCR in the budding yeast Saccharomyces cerevisiae
    STAR Protoc, 3 (1), 101210
    DOI 10.1016/j.xpro.2022.101210, PubMed 35265859
  35. Romaine A, Melleby AO, Alam J, Lobert VH, Lu N, Lockwood FE, Hasic A, Lunde IG, Sjaastad I, Stenmark H, Herum KM, Gullberg D, Christensen G (2022)
    Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart
    Am J Physiol Heart Circ Physiol, 322 (6), H1057-H1071
    DOI 10.1152/ajpheart.00635.2021, PubMed 35522553
  36. Sandvig K, Kavaliauskiene S, Myrann AG, Iversen TG, Skotland T (2022)
    Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC
    Toxins (Basel), 14 (5)
    DOI 10.3390/toxins14050360, PubMed 35622606
  37. Sikkeland J, Ng MYW, Nenseth HZ, Unal B, Qu S, Jin Y, Simonsen A, Saatcioglu F (2022)
    STAMP2 suppresses autophagy in prostate cancer cells by modulating the integrated stress response pathway
    Am J Cancer Res, 12 (1), 327-336
    PubMed 35141021
  38. Simonsen A, Wollert T (2022)
    Don't forget to be picky - selective autophagy of protein aggregates in neurodegenerative diseases
    Curr Opin Cell Biol, 75, 102064
    DOI 10.1016/j.ceb.2022.01.009, PubMed 35240373
  39. Skotland T, Iversen TG, Llorente A, Sandvig K (2022)
    Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges
    Adv Drug Deliv Rev, 186, 114326
    DOI 10.1016/j.addr.2022.114326, PubMed 35588953
  40. Skotland T, Sandvig K (2022)
    Need for more focus on lipid species in studies of biological and model membranes
    Prog Lipid Res, 86, 101160
    DOI 10.1016/j.plipres.2022.101160, PubMed 35288150
  41. Stanciu SG, Hristu R, Stanciu GA, Tranca DE, Eftimie L, Dumitru A, Costache M, Stenmark HA, Manders H, Cherian A, Tark-Dame M, Manders EMM (2022)
    Super-resolution re-scan second harmonic generation microscopy
    Proc Natl Acad Sci U S A, 119 (47), e2214662119
    DOI 10.1073/pnas.2214662119, PubMed 36375085
  42. Stanciu SG, Tranca DE, Zampini G, Hristu R, Stanciu GA, Chen X, Liu M, Stenmark HA, Latterini L (2022)
    Scattering-type Scanning Near-Field Optical Microscopy of Polymer-Coated Gold Nanoparticles
    ACS Omega, 7 (13), 11353-11362
    DOI 10.1021/acsomega.2c00410, PubMed 35415325
  43. Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
    ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
    J Cell Sci, 135 (4)
    DOI 10.1242/jcs.259138, PubMed 35099014
  44. Wenzel EM, Elfmark LA, Stenmark H, Raiborg C (2022)
    ER as master regulator of membrane trafficking and organelle function
    J Cell Biol, 221 (10)
    DOI 10.1083/jcb.202205135, PubMed 36108241
  45. Wenzel EM, Raiborg C (2022)
    ER-endosome contacts master the ins and outs of secretory endosomes
    J Cell Biol, 221 (12)
    DOI 10.1083/jcb.202210033, PubMed 36355088
  46. Xu J, Yang KC, Go NE, Colborne S, Ho CJ, Hosseini-Beheshti E, Lystad AH, Simonsen A, Guns ET, Morin GB, Gorski SM (2022)
    Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
    Autophagy, 18 (11), 2547-2560
    DOI 10.1080/15548627.2022.2039535, PubMed 35220892
  47. Zendrini A, Guerra G, Sagini K, Vagner T, Di Vizio D, Bergese P (2022)
    On the surface-to-bulk partition of proteins in extracellular vesicles
    Colloids Surf B Biointerfaces, 218, 112728
    DOI 10.1016/j.colsurfb.2022.112728, PubMed 35969923
  48. Zhao X, Hendriks IA, Le Gras S, Ye T, Ramos-Alonso L, Nguéa P A, Lien GF, Ghasemi F, Klungland A, Jost B, Enserink JM, Nielsen ML, Chymkowitch P (2022)
    Waves of sumoylation support transcription dynamics during adipocyte differentiation
    Nucleic Acids Res, 50 (3), 1351-1369
    DOI 10.1093/nar/gkac027, PubMed 35100417

Publications 2021

  1. Agudo-Canalejo J, Schultz SW, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, May AI, Mizushima N, Knorr RL (2021)
    Wetting regulates autophagy of phase-separated compartments and the cytosol
    Nature, 591 (7848), 142-146
    DOI 10.1038/s41586-020-2992-3, PubMed 33473217
  2. Aman Y, Schmauck-Medina T, Hansen M, Morimoto RI, Simon AK, Bjedov I, Palikaras K, Simonsen A, Johansen T, Tavernarakis N, Rubinsztein DC, Partridge L, Kroemer G, Labbadia J, Fang EF (2021)
    Autophagy in healthy aging and disease
    Nat Aging, 1 (8), 634-650
    DOI 10.1038/s43587-021-00098-4, PubMed 34901876
  3. Anda S, Boye E, Schink KO, Grallert B (2021)
    Cosegregation of asymmetric features during cell division
    Open Biol, 11 (8), 210116
    DOI 10.1098/rsob.210116, PubMed 34343465
  4. Bjørnetrø T, Steffensen LA, Vestad B, Brusletto BS, Olstad OK, Trøseid AM, Aass HCD, Haug KBF, Llorente A, Bøe SO, Lång A, Samiappan R, Redalen KR, Øvstebø R, Ree AH (2021)
    Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
    FEBS Open Bio, 11 (3), 724-740
    DOI 10.1002/2211-5463.13098, PubMed 33512765
  5. Buratta S, Shimanaka Y, Costanzi E, Ni S, Urbanelli L, Kono N, Morena F, Sagini K, Giovagnoli S, Romani R, Gargaro M, Arai H, Emiliani C (2021)
    Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
    Sci Rep, 11 (1), 4613
    DOI 10.1038/s41598-021-84268-9, PubMed 33633289
  6. Caulier B, Enserink JM, Wälchli S (2021)
    Pharmacologic Control of CAR T Cells
    Int J Mol Sci, 22 (9)
    DOI 10.3390/ijms22094320, PubMed 33919245
  7. Dillard C, Reis JGT, Rusten TE (2021)
    RasV12; scrib-/- Tumors: A Cooperative Oncogenesis Model Fueled by Tumor/Host Interactions
    Int J Mol Sci, 22 (16)
    DOI 10.3390/ijms22168873, PubMed 34445578
  8. Erdbrügger U, Blijdorp CJ, Bijnsdorp IV, Borràs FE, Burger D, Bussolati B, Byrd JB, Clayton A, Dear JW, Falcón-Pérez JM, Grange C, Hill AF, Holthöfer H, Hoorn EJ, Jenster G, Jimenez CR, Junker K, Klein J, Knepper MA, Koritzinsky EH, Luther JM, Lenassi M, Leivo J, Mertens I, Musante L et al. (2021)
    Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
    J Extracell Vesicles, 10 (7), e12093
    DOI 10.1002/jev2.12093, PubMed 34035881
  9. Fernandes P, Miotto B, Saint-Ruf C, Said M, Barra V, Nähse V, Ravera S, Cappelli E, Naim V (2021)
    FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
    Commun Biol, 4 (1), 127
    DOI 10.1038/s42003-021-01647-8, PubMed 33514811
  10. Fløisand Y, Schroeder MA, Chevallier P, Selleslag D, Devine S, Renteria AS, Mohty M, Yakoub-Agha I, Chen C, Parfionovas A, Quadri S, Jansson J, Akbari M, Chen YB (2021)
    A phase 2a randomized clinical trial of intravenous vedolizumab for the treatment of steroid-refractory intestinal acute graft-versus-host disease
    Bone Marrow Transplant, 56 (10), 2477-2488
    DOI 10.1038/s41409-021-01356-0, PubMed 34108672
  11. Formica M, Storaci AM, Bertolini I, Carminati F, Knævelsrud H, Vaira V, Vaccari T (2021)
    V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis
    Autophagy, 17 (12), 4442-4452
    DOI 10.1080/15548627.2021.1918915, PubMed 33978540
  12. Garcia I, Orellana-Muñoz S, Ramos-Alonso L, Andersen AN, Zimmermann C, Eriksson J, Bøe SO, Kaferle P, Papamichos-Chronakis M, Chymkowitch P, Enserink JM (2021)
    Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
    Cell Rep, 37 (13), 110186
    DOI 10.1016/j.celrep.2021.110186, PubMed 34965431
  13. Giovannucci TA, Salomons FA, Stoy H, Herzog LK, Xu S, Qian W, Merino LG, Gierisch ME, Haraldsson M, Lystad AH, Uvell H, Simonsen A, Gustavsson AL, Vallin M, Dantuma NP (2021)
    Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
    Autophagy, 18 (7), 1486-1502
    DOI 10.1080/15548627.2021.1988359, PubMed 34740308
  14. Grad I, Hanes R, Ayuda-Durán P, Kuijjer ML, Enserink JM, Meza-Zepeda LA, Myklebost O (2021)
    Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
    PLoS One, 16 (3), e0248140
    DOI 10.1371/journal.pone.0248140, PubMed 33690666
  15. Guerriero I, Ramberg H, Sagini K, Ramirez-Garrastacho M, Taskén KA, Llorente A (2021)
    Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells
    PLoS One, 16 (6), e0253828
    DOI 10.1371/journal.pone.0253828, PubMed 34191854
  16. Holland P, Hagopian WM, Jahren AH, Rusten TE (2021)
    Natural abundance isotope ratios to differentiate sources of carbon used during tumor growth in vivo
    BMC Biol, 19 (1), 85
    DOI 10.1186/s12915-021-01012-5, PubMed 33966633
  17. Iglesias R, Ferreras JM, Llorente A, Citores L (2021)
    Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication
    Toxins (Basel), 13 (2)
    DOI 10.3390/toxins13020102, PubMed 33573355
  18. Khezri R, Holland P, Schoborg TA, Abramovich I, Takáts S, Dillard C, Jain A, O'Farrell F, Schultz SW, Hagopian WM, Quintana EM, Ng R, Katheder NS, Rahman MM, Teles Reis JG, Brech A, Jasper H, Rusan NM, Jahren AH, Gottlieb E, Rusten TE (2021)
    Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
    EMBO J, 40 (18), e107336
    DOI 10.15252/embj.2020107336, PubMed 34309071
  19. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
    Autophagy, 17 (1), 1-382
    DOI 10.1080/15548627.2020.1797280, PubMed 33634751
  20. Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen EL, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T et al. (2021)
    Autophagy in major human diseases
    EMBO J, 40 (19), e108863
    DOI 10.15252/embj.2021108863, PubMed 34459017
  21. Kosanović M, Llorente A, Glamočlija S, Valdivielso JM, Bozic M (2021)
    Extracellular Vesicles and Renal Fibrosis: An Odyssey toward a New Therapeutic Approach
    Int J Mol Sci, 22 (8)
    DOI 10.3390/ijms22083887, PubMed 33918699
  22. Krzyscik MA, Zakrzewska M, Sørensen V, Øy GF, Brunheim S, Haugsten EM, Mælandsmo GM, Wiedlocha A, Otlewski J (2021)
    Fibroblast Growth Factor 2 Conjugated with Monomethyl Auristatin E Inhibits Tumor Growth in a Mouse Model
    Biomacromolecules, 22 (10), 4169-4180
    DOI 10.1021/acs.biomac.1c00662, PubMed 34542998
  23. Martens-Uzunova ES, Blijdorp CJ, Burger D, Erdbrügger U, Llorente A (2021)
    Urinary Extracellular Vesicles in Urology: Current Successes and Challenges Ahead
    Eur Urol, 81 (1), 127-128
    DOI 10.1016/j.eururo.2021.09.025, PubMed 34625312
  24. Melvold K, Giliberto M, Karlsen L, Ayuda-Durán P, Hanes R, Holien T, Enserink J, Brown JR, Tjønnfjord GE, Taskén K, Skånland SS (2021)
    Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
    Mol Oncol, 16 (5), 1153-1170
    DOI 10.1002/1878-0261.13153, PubMed 34861096
  25. Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A (2021)
    GAK and PRKCD are positive regulators of PRKN-independent mitophagy
    Nat Commun, 12 (1), 6101
    DOI 10.1038/s41467-021-26331-7, PubMed 34671015
  26. Mygland L, Brinch SA, Strand MF, Olsen PA, Aizenshtadt A, Lund K, Solberg NT, Lycke M, Thorvaldsen TE, Espada S, Misaghian D, Page CM, Agafonov O, Nygård S, Chi NW, Lin E, Tan J, Yu Y, Costa M, Krauss S, Waaler J (2021)
    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
    iScience, 24 (7), 102807
    DOI 10.1016/j.isci.2021.102807, PubMed 34337362
  27. Nowosielska EM, Cheda A, Pociegiel M, Cheda L, Szymański P, Wiedlocha A (2021)
    Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice
    Int J Mol Sci, 22 (12)
    DOI 10.3390/ijms22126309, PubMed 34208396
  28. Pandya AD, Iversen TG, Moestue S, Grinde MT, Mørch Ý, Snipstad S, Åslund AKO, Øy GF, Kildal W, Engebråten O, Sandvig K, Skotland T, Mælandsmo GM (2021)
    Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
    Nanomaterials (Basel), 11 (5)
    DOI 10.3390/nano11051140, PubMed 33924869
  29. Ramirez-Garrastacho M, Bajo-Santos C, Line A, Martens-Uzunova ES, de la Fuente JM, Moros M, Soekmadji C, Tasken KA, Llorente A (2021)
    Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research
    Br J Cancer, 126 (3), 331-350
    DOI 10.1038/s41416-021-01610-8, PubMed 34811504
  30. Ramirez-Garrastacho M, Berge V, Linē A, Llorente A (2021)
    Potential of miRNAs in urinary extracellular vesicles for management of active surveillance in prostate cancer patients
    Br J Cancer, 126 (3), 492-501
    DOI 10.1038/s41416-021-01598-1, PubMed 34811506
  31. Ravussin A, Brech A, Tooze SA, Stenmark H (2021)
    The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy
    J Cell Sci, 134 (3)
    DOI 10.1242/jcs.250670, PubMed 33468622
  32. Rudolph MJ, Poon AY, Kavaliauskiene S, Myrann AG, Reynolds-Peterson C, Davis SA, Sandvig K, Vance DJ, Mantis NJ (2021)
    Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface
    J Mol Biol, 433 (15), 167086
    DOI 10.1016/j.jmb.2021.167086, PubMed 34089718
  33. Rønneberg L, Cremaschi A, Hanes R, Enserink JM, Zucknick M (2021)
    bayesynergy: flexible Bayesian modelling of synergistic interaction effects in in vitro drug combination experiments
    Brief Bioinform, 22 (6)
    DOI 10.1093/bib/bbab251, PubMed 34308471
  34. Sandvig K, Kavaliauskiene S, Skotland T (2021)
    The Protein Toxins Ricin and Shiga Toxin as Tools to Explore Cellular Mechanisms of Internalization and Intracellular Transport
    Toxins (Basel), 13 (6)
    DOI 10.3390/toxins13060377, PubMed 34070659
  35. Schink KO, Tan KW, Spangenberg H, Martorana D, Sneeggen M, Stévenin V, Enninga J, Campsteijn C, Raiborg C, Stenmark H (2021)
    The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes
    Nat Commun, 12 (1), 6577
    DOI 10.1038/s41467-021-26775-x, PubMed 34772942
  36. Schultz SW, Agudo-Canalejo J, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, Mizushima N, Knorr RL, May AI (2021)
    Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
    Autophagy, 17 (4), 1046-1048
    DOI 10.1080/15548627.2021.1887548, PubMed 33629888
  37. Sharma K, Asp NT, Harrison S, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A (2021)
    Autophagy modulates cell fate decisions during lineage commitment
    Autophagy, 18 (8), 1915-1931
    DOI 10.1080/15548627.2021.2008691, PubMed 34923909
  38. Siokis A, Robert PA, Demetriou P, Kvalvaag A, Valvo S, Mayya V, Dustin ML, Meyer-Hermann M (2021)
    Characterization of mechanisms positioning costimulatory complexes in immune synapses
    iScience, 24 (10), 103100
    DOI 10.1016/j.isci.2021.103100, PubMed 34622155
  39. Skotland T, Iversen TG, Sandvig K (2021)
    Cellular uptake of nanoparticles: Involvement of caveolae?
    Precis Nanomed, 4 (2), 782-786
    DOI 10.33218/001c.22201, PublikaID 365
  40. Skotland T, Sandvig K (2021)
    Transport of nanoparticles across the endothelial cell layer
    Nano Today, 36, 101029
    DOI 10.1016/j.nantod.2020.101029
  41. Szybowska P, Kostas M, Wesche J, Haugsten EM, Wiedlocha A (2021)
    Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
    Cells, 10 (6)
    DOI 10.3390/cells10061342, PubMed 34071546
  42. Sønstevold T, Engedal N, Torgersen ML (2021)
    Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy
    Cells, 10 (12)
    DOI 10.3390/cells10123432, PubMed 34943939
  43. Tan KW (2021)
    First person - Kia Wee Tan
    J. Cell Sci., 134 (14), jcs259055
    DOI 10.1242/jcs.259055
  44. Tan KW, Nähse V, Campsteijn C, Brech A, Schink KO, Stenmark H (2021)
    JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes
    J Cell Sci, 134 (14)
    DOI 10.1242/jcs.258495, PubMed 34109410
  45. Valko A, Perez-Pandolfo S, Sorianello E, Brech A, Wappner P, Melani M (2021)
    Adaptation to hypoxia in Drosophila melanogaster requires autophagy
    Autophagy, 18 (4), 909-920
    DOI 10.1080/15548627.2021.1991191, PubMed 34793268
  46. Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
    Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
    Int J Pharm, 597, 120217
    DOI 10.1016/j.ijpharm.2021.120217, PubMed 33486035
  47. Weisheit S, Wegner CS, Ailte I, Radulovic M, Weyergang A, Selbo PK, Brech A (2021)
    Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
    Biochem Pharmacol, 194, 114837
    DOI 10.1016/j.bcp.2021.114837, PubMed 34780750
  48. Wiedlocha A, Haugsten EM, Zakrzewska M (2021)
    Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation
    Cells, 10 (9)
    DOI 10.3390/cells10092231, PubMed 34571880
  49. Wirth M, Mouilleron S, Zhang W, Sjøttem E, Abudu YP, Jain A, Olsvik HL, Bruun JA, Razi M, Jefferies HBJ, Lee R, Joshi D, O'Reilly N, Johansen T, Tooze SA (2021)
    Corrigendum to Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
    J Mol Biol, 433 (15), 167049
    DOI 10.1016/j.jmb.2021.167049, PubMed 34052024
  50. Wirth M, Mouilleron S, Zhang W, Sjøttem E, Princely Abudu Y, Jain A, Lauritz Olsvik H, Bruun JA, Razi M, Jefferies HBJ, Lee R, Joshi D, O'Reilly N, Johansen T, Tooze SA (2021)
    Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
    J Mol Biol, 433 (13), 166987
    DOI 10.1016/j.jmb.2021.166987, PubMed 33845085
  51. Zdżalik-Bielecka D, Poświata A, Kozik K, Jastrzębski K, Schink KO, Brewińska-Olchowik M, Piwocka K, Stenmark H, Miączyńska M (2021)
    The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion
    Proc Natl Acad Sci U S A, 118 (28)
    DOI 10.1073/pnas.2024596118, PubMed 34244439
  52. Zhen Y, Radulovic M, Vietri M, Stenmark H (2021)
    Sealing holes in cellular membranes
    EMBO J, 40 (7), e106922
    DOI 10.15252/embj.2020106922, PubMed 33644904
  53. Øverbye A, Torgersen ML, Sønstevold T, Iversen TG, Mørch Ý, Skotland T, Sandvig K (2021)
    Cabazitaxel-loaded poly(alkyl cyanoacrylate) nanoparticles: toxicity and changes in the proteome of breast, colon and prostate cancer cells
    Nanotoxicology, 15 (7), 865-884
    DOI 10.1080/17435390.2021.1924888, PubMed 34047629

Publications 2020

  1. Buratta S, Tancini B, Sagini K, Delo F, Chiaradia E, Urbanelli L, Emiliani C (2020)
    Lysosomal Exocytosis, Exosome Release and Secretory Autophagy: The Autophagic- and Endo-Lysosomal Systems Go Extracellular
    Int J Mol Sci, 21 (7)
    DOI 10.3390/ijms21072576, PubMed 32276321
  2. Caglayan S, Hashim A, Cieslar-Pobuda A, Jensen V, Behringer S, Talug B, Chu DT, Pecquet C, Rogne M, Brech A, Brorson SH, Nagelhus EA, Hannibal L, Boschi A, Taskén K, Staerk J (2020)
    Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
    iScience, 23 (6), 101154
    DOI 10.1016/j.isci.2020.101154, PubMed 32450518
  3. Dillard P, Lie M, Baken E, Lobert VH, Benard E, Köksal H, Inderberg EM, Wälchli S (2020)
    Colorectal cysts as a validating tool for CAR therapy
    BMC Biotechnol, 20 (1), 30
    DOI 10.1186/s12896-020-00623-0, PubMed 32487146
  4. Grønvold B, Ali MM, Remberger M, Mattsson J, Egeland T, Lundin KU, Myhre AE, Abrahamsen IW, Heldal D, Dybedal I, Tjønnfjord GE, Fløisand Y, Gedde-Dahl T (2020)
    HLA-DPB1 mismatch reduce relapse and improve survival in T-cell replete unrelated donor allogeneic stem cell transplantation
    Bone Marrow Transplant, 55 (8), 1658-1661
    DOI 10.1038/s41409-020-0827-3, PubMed 32054997
  5. Jacomin AC, Gohel R, Hussain Z, Varga A, Maruzs T, Eddison M, Sica M, Jain A, Moffat KG, Johansen T, Jenny A, Juhasz G, Nezis IP (2020)
    Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila
    Life Sci Alliance, 4 (2)
    DOI 10.26508/lsa.202000965, PubMed 33318080
  6. Jacomin AC, Petridi S, Di Monaco M, Bhujabal Z, Jain A, Mulakkal NC, Palara A, Powell EL, Chung B, Zampronio C, Jones A, Cameron A, Johansen T, Nezis IP (2020)
    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
    Cell Rep, 31 (8), 107695
    DOI 10.1016/j.celrep.2020.107695, PubMed 32460019
  7. Jakobi AJ, Huber ST, Mortensen SA, Schultz SW, Palara A, Kuhm T, Shrestha BK, Lamark T, Hagen WJH, Wilmanns M, Johansen T, Brech A, Sachse C (2020)
    Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake
    Nat Commun, 11 (1), 440
    DOI 10.1038/s41467-020-14343-8, PubMed 31974402
  8. Jena KK, Mehto S, Nath P, Chauhan NR, Sahu R, Dhar K, Das SK, Kolapalli SP, Murmu KC, Jain A, Krishna S, Sahoo BS, Chattopadhyay S, Rusten TE, Prasad P, Chauhan S, Chauhan S (2020)
    Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response
    EMBO Rep, 21 (9), e50051
    DOI 10.15252/embr.202050051, PubMed 32715615
  9. Jendryczko K, Chudzian J, Skinder N, Opaliński Ł, Rzeszótko J, Wiedlocha A, Otlewski J, Szlachcic A (2020)
    FGF2-Derived PeptibodyF2-MMAE Conjugate for Targeted Delivery of Cytotoxic Drugs into Cancer Cells Overexpressing FGFR1
    Cancers (Basel), 12 (10)
    DOI 10.3390/cancers12102992, PubMed 33076489
  10. Kolapalli SP, Sahu R, Chauhan NR, Jena KK, Mehto S, Das SK, Jain A, Rout M, Dash R, Swain RK, Lee DY, Rusten TE, Chauhan S, Chauhan S (2020)
    RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression
    Cancer Res, 81 (2), 315-331
    DOI 10.1158/0008-5472.CAN-20-1871, PubMed 33067265
  11. Kumar S, Jain A, Choi SW, da Silva GPD, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
    Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
    Nat Cell Biol, 22 (8), 973-985
    DOI 10.1038/s41556-020-0549-1, PubMed 32753672
  12. Kumar S, Jain A, Choi SW, da Silva GPD, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
    Author Correction: Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
    Nat Cell Biol, 22 (10), 1286
    DOI 10.1038/s41556-020-0574-0, PubMed 32788721
  13. Kumar S, Jain A, Choi SW, Peixoto Duarte da Silva G, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V (2020)
    Mammalian Atg8-family proteins are upstream regulators of the lysosomalsystem by controlling MTOR and TFEB
    Autophagy, 16 (12), 2305-2306
    DOI 10.1080/15548627.2020.1837423, PubMed 33070669
  14. Laiouar S, Berns N, Brech A, Riechmann V (2020)
    RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism
    Curr Biol, 30 (7), 1177-1188.e5
    DOI 10.1016/j.cub.2020.01.048, PubMed 32059769
  15. Liese S, Wenzel EM, Kjos I, Rojas Molina R, Schultz SW, Brech A, Stenmark H, Raiborg C, Carlson A (2020)
    Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles
    Proc Natl Acad Sci U S A, 117 (46), 28614-28624
    DOI 10.1073/pnas.2014228117, PubMed 33139578
  16. Lingelem ABD, Kavaliauskiene S, Halsne R, Klokk TI, Surma MA, Klose C, Skotland T, Sandvig K (2020)
    Diacylglycerol kinase and phospholipase D inhibitors alter the cellular lipidome and endosomal sorting towards the Golgi apparatus
    Cell Mol Life Sci, 78 (3), 985-1009
    DOI 10.1007/s00018-020-03551-6, PubMed 32447426
  17. Martín-Gracia B, Martín-Barreiro A, Cuestas-Ayllón C, Grazú V, Line A, Llorente A, M de la Fuente J, Moros M (2020)
    Nanoparticle-based biosensors for detection of extracellular vesicles in liquid biopsies
    J Mater Chem B, 8 (31), 6710-6738
    DOI 10.1039/d0tb00861c, PubMed 32627783
  18. Mastrangelopoulou M, Grigalavicius M, Raabe TH, Skarpen E, Juzenas P, Peng Q, Berg K, Theodossiou TA (2020)
    Predictive biomarkers for 5-ALA-PDT can lead to personalized treatments and overcome tumor-specific resistances
    Cancer Rep (Hoboken), 5 (12), e1278
    DOI 10.1002/cnr2.1278, PubMed 32737955
  19. Munthe E, Raiborg C, Stenmark H, Wenzel EM (2020)
    Clathrin regulates Wnt/β-catenin signaling by affecting Golgi to plasma membrane transport of transmembrane proteins
    J Cell Sci, 133 (13)
    DOI 10.1242/jcs.244467, PubMed 32546530
  20. Nakstad ER, Stær-Jensen H, Wimmer H, Henriksen J, Alteheld LH, Reichenbach A, Drægni T, Šaltytė-Benth J, Wilson JA, Etholm L, Øijordsbakken M, Eritsland J, Seljeflot I, Jacobsen D, Andersen GØ, Lundqvist C, Sunde K (2020)
    Late awakening, prognostic factors and long-term outcome in out-of-hospital cardiac arrest - results of the prospective Norwegian Cardio-Respiratory Arrest Study (NORCAST)
    Resuscitation, 149, 170-179
    DOI 10.1016/j.resuscitation.2019.12.031, PubMed 31926258
  21. Ohnstad AE, Delgado JM, North BJ, Nasa I, Kettenbach AN, Schultz SW, Shoemaker CJ (2020)
    Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
    EMBO J, 39 (24), e104948
    DOI 10.15252/embj.2020104948, PubMed 33226137
  22. Omsland M, Andresen V, Gullaksen SE, Ayuda-Durán P, Popa M, Hovland R, Brendehaug A, Enserink J, McCormack E, Gjertsen BT (2020)
    Tyrosine kinase inhibitors and interferon-α increase tunneling nanotube (TNT) formation and cell adhesion in chronic myeloid leukemia (CML) cell lines
    FASEB J, 34 (3), 3773-3791
    DOI 10.1096/fj.201802061RR, PubMed 31945226
  23. Palušová V, Renzová T, Verlande A, Vaclová T, Medková M, Cetlová L, Sedláčková M, Hříbková H, Slaninová I, Krutá M, Rotrekl V, Uhlířová H, Křížová A, Chmelík R, Veselý P, Krafčíková M, Trantírek L, Schink KO, Uldrijan S (2020)
    Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds
    Cancers (Basel), 12 (6)
    DOI 10.3390/cancers12061516, PubMed 32531927
  24. Pandya AD, Øverbye A, Sahariah P, Gaware VS, Høgset H, Masson M, Høgset A, Mælandsmo GM, Skotland T, Sandvig K, Iversen TG (2020)
    Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
    Biomacromolecules, 21 (4), 1489-1498
    DOI 10.1021/acs.biomac.0c00061, PubMed 32092254
  25. Parfejevs V, Sagini K, Buss A, Sobolevska K, Llorente A, Riekstina U, Abols A (2020)
    Adult Stem Cell-Derived Extracellular Vesicles in Cancer Treatment: Opportunities and Challenges
    Cells, 9 (5)
    DOI 10.3390/cells9051171, PubMed 32397238
  26. Pedersen NM, Wenzel EM, Wang L, Antoine S, Chavrier P, Stenmark H, Raiborg C (2020)
    Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion
    J Cell Biol, 219 (8)
    DOI 10.1083/jcb.202003063, PubMed 32479595
  27. Radulovic M, Stenmark H (2020)
    LRRK2 to the rescue of damaged endomembranes
    EMBO J, 39 (18), e106162
    DOI 10.15252/embj.2020106162, PubMed 32803793
  28. Remberger M, Grønvold B, Ali M, Mattsson J, Egeland T, Lundin KU, Myhre A, Abrahamsen I, Heldal D, Dybedal I, Tjønnfjord GE, Gedde-Dahl T, Fløisand Y (2020)
    The CD34+ Cell Dose Matters in Hematopoietic Stem Cell Transplantation with Peripheral Blood Stem Cells from Sibling Donors
    Clin Hematol Int, 2 (2), 74-81
    DOI 10.2991/chi.d.200221.001, PubMed 34595446
  29. Skotland T, Kavaliauskiene S, Sandvig K (2020)
    The role of lipid species in membranes and cancer-related changes
    Cancer Metastasis Rev, 39 (2), 343-360
    DOI 10.1007/s10555-020-09872-z, PubMed 32314087
  30. Skotland T, Sagini K, Sandvig K, Llorente A (2020)
    An emerging focus on lipids in extracellular vesicles
    Adv Drug Deliv Rev, 159, 308-321
    DOI 10.1016/j.addr.2020.03.002, PubMed 32151658
  31. Solhaug A, Torgersen ML, Holme JA, Wiik-Nilsen J, Thiede B, Eriksen GS (2020)
    The Fusarium mycotoxin, 2-Amino-14,16-dimethyloctadecan-3-ol (AOD) induces vacuolization in HepG2 cells
    Toxicology, 433-434, 152405
    DOI 10.1016/j.tox.2020.152405, PubMed 32044396
  32. Szwed M, Torgersen ML, Kumari RV, Yadava SK, Pust S, Iversen TG, Skotland T, Giri J, Sandvig K (2020)
    Biological response and cytotoxicity induced by lipid nanocapsules
    J Nanobiotechnology, 18 (1), 5
    DOI 10.1186/s12951-019-0567-y, PubMed 31907052
  33. Sønstevold T, Engedal N, Mørch Ý, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2020)
    Structural Variants of poly(alkylcyanoacrylate) Nanoparticles Differentially Affect LC3 and Autophagic Cargo Degradation
    J Biomed Nanotechnol, 16 (4), 432-445
    DOI 10.1166/jbn.2020.2906, PubMed 32970976
  34. Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnová M, Piechaczyk L, Ayuda-Durán P, Singh SK, Gedde-Dahl T, Fløisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM (2020)
    A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
    J Biol Chem, 296, 100179
    DOI 10.1074/jbc.RA120.015285, PubMed 33303632
  35. Torgersen ML, Judge PJ, Bada Juarez JF, Pandya AD, Fusser M, Davies CW, Maciejewska MK, Yin DJ, Maelandsmo GM, Skotland T, Watts A, Sandvig K (2020)
    Physicochemical Characterization, Toxicity and In Vivo Biodistribution Studies of a Discoidal, Lipid-Based Drug Delivery Vehicle: Lipodisq Nanoparticles Containing Doxorubicin
    J Biomed Nanotechnol, 16 (4), 419-431
    DOI 10.1166/jbn.2020.2911, PubMed 32970975
  36. Tsjokajev A, Røberg-Larsen H, Wilson SR, Dyve Lingelem AB, Skotland T, Sandvig K, Lundanes E (2020)
    Mass spectrometry-based measurements of cyclic adenosine monophosphate in cells, simplified using reversed phase liquid chromatography with a polar characterized stationary phase
    J Chromatogr B Analyt Technol Biomed Life Sci, 1160, 122384
    DOI 10.1016/j.jchromb.2020.122384, PubMed 32971370
  37. Van Gool A, Corrales F, Čolović M, Krstić D, Oliver-Martos B, Martínez-Cáceres E, Jakasa I, Gajski G, Brun V, Kyriacou K, Burzynska-Pedziwiatr I, Wozniak LA, Nierkens S, Pascual García C, Katrlik J, Bojic-Trbojevic Z, Vacek J, Llorente A, Antohe F, Suica V, Suarez G, t'Kindt R, Martin P, Penque D, Martins IL et al. (2020)
    Analytical techniques for multiplex analysis of protein biomarkers
    Expert Rev Proteomics, 17 (4), 257-273
    DOI 10.1080/14789450.2020.1763174, PubMed 32427033
  38. Vietri M, Schultz SW, Bellanger A, Jones CM, Petersen LI, Raiborg C, Skarpen E, Pedurupillay CRJ, Kjos I, Kip E, Timmer R, Jain A, Collas P, Knorr RL, Grellscheid SN, Kusumaatmaja H, Brech A, Micci F, Stenmark H, Campsteijn C (2020)
    Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
    Nat Cell Biol, 22 (7), 856-867
    DOI 10.1038/s41556-020-0537-5, PubMed 32601372
  39. Welsh JA, van der Pol E, Bettin BA, Carter DRF, Hendrix A, Lenassi M, Langlois MA, Llorente A, van de Nes AS, Nieuwland R, Tang V, Wang L, Witwer KW, Jones JC (2020)
    Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration
    J Extracell Vesicles, 9 (1), 1816641
    DOI 10.1080/20013078.2020.1816641, PubMed 33062218
  40. Wong JJW, Berstad MB, Fremstedal ASV, Berg K, Patzke S, Sørensen V, Peng Q, Selbo PK, Weyergang A (2020)
    Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy
    Cancers (Basel), 12 (2)
    DOI 10.3390/cancers12020417, PubMed 32053965
  41. Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
    STEEP mediates STING ER exit and activation of signaling
    Nat Immunol, 21 (8), 868-879
    DOI 10.1038/s41590-020-0730-5, PubMed 32690950
  42. Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R et al. (2020)
    Author Correction: STEEP mediates STING ER exit and activation of signaling
    Nat Immunol, 21 (11), 1468-1469
    DOI 10.1038/s41590-020-0803-5, PubMed 32929276

Publications 2019

  1. Brison O, El-Hilali S, Azar D, Koundrioukoff S, Schmidt M, Nähse V, Jaszczyszyn Y, Lachages AM, Dutrillaux B, Thermes C, Debatisse M, Chen CL (2019)
    Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide
    Nat Commun, 10 (1), 5693
    DOI 10.1038/s41467-019-13674-5, PubMed 31836700
  2. Dillard C, Rusten TE (2019)
    Cell Competition Triggers Suicide by Autophagy
    Dev Cell, 51 (1), 4-5
    DOI 10.1016/j.devcel.2019.09.014, PubMed 31593651
  3. Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE et al. (2019)
    NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
    Nat Commun, 10 (1), 5284
    DOI 10.1038/s41467-019-13172-8, PubMed 31754102
  4. Frikstad KM, Molinari E, Thoresen M, Ramsbottom SA, Hughes F, Letteboer SJF, Gilani S, Schink KO, Stokke T, Geimer S, Pedersen LB, Giles RH, Akhmanova A, Roepman R, Sayer JA, Patzke S (2019)
    A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
    Cell Rep, 28 (7), 1907-1922.e6
    DOI 10.1016/j.celrep.2019.07.025, PubMed 31412255
  5. Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ (2019)
    Remodeling of secretory lysosomes during education tunes functional potential in NK cells
    Nat Commun, 10 (1), 514
    DOI 10.1038/s41467-019-08384-x, PubMed 30705279
  6. Hoem G, Bowitz Larsen K, Øvervatn A, Brech A, Lamark T, Sjøttem E, Johansen T (2019)
    The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS
    Front Genet, 10, 249
    DOI 10.3389/fgene.2019.00249, PubMed 30984240
  7. Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen JC, Eibes S, Maiani E, Harder LM, Wesch N, Foged MM, Maeda K, Nazio F, de la Ballina LR, Dötsch V, Brech A, Frankel LB, Jäättelä M, Locatelli F, Barisic M, Andersen JS, Bekker-Jensen S, Lund AH, Rogov VV, Papaleo E et al. (2019)
    Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites
    Nat Commun, 10 (1), 4176
    DOI 10.1038/s41467-019-12094-9, PubMed 31519908
  8. Khezri R, Rusten TE (2019)
    Autophagy and Tumorigenesis in Drosophila
    Adv Exp Med Biol, 1167, 113-127
    DOI 10.1007/978-3-030-23629-8_7, PubMed 31520352
  9. Khezri R, Rusten TE (2019)
    Correction to: Autophagy and Tumorigenesis in Drosophila
    Adv Exp Med Biol, 1167, C1
    DOI 10.1007/978-3-030-23629-8_15, PubMed 33306185
  10. Kumar S, Gu Y, Abudu YP, Bruun JA, Jain A, Farzam F, Mudd M, Anonsen JH, Rusten TE, Kasof G, Ktistakis N, Lidke KA, Johansen T, Deretic V (2019)
    Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation
    Dev Cell, 49 (1), 130-144.e6
    DOI 10.1016/j.devcel.2019.01.027, PubMed 30827897
  11. Lie-Jensen A, Ivanauskiene K, Malerød L, Jain A, Tan KW, Laerdahl JK, Liestøl K, Stenmark H, Haglund K (2019)
    Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
    Curr Biol, 29 (20), 3538-3548.e7
    DOI 10.1016/j.cub.2019.09.025, PubMed 31607533
  12. Luhr M, Torgersen ML, Szalai P, Hashim A, Brech A, Staerk J, Engedal N (2019)
    The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress
    J Biol Chem, 294 (20), 8197-8217
    DOI 10.1074/jbc.RA118.002829, PubMed 30926605
  13. Mehto S, Jena KK, Nath P, Chauhan S, Kolapalli SP, Das SK, Sahoo PK, Jain A, Taylor GA, Chauhan S (2019)
    The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy
    Mol Cell, 73 (3), 429-445.e7
    DOI 10.1016/j.molcel.2018.11.018, PubMed 30612879
  14. Moghimi SM, Simberg D, Skotland T, Yaghmur A, Hunter AC (2019)
    The Interplay Between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses
    J Pharmacol Exp Ther, 370 (3), 581-592
    DOI 10.1124/jpet.119.258012, PubMed 30940695
  15. Nguéa P A, Robertson J, Herrera MC, Chymkowitch P, Enserink JM (2019)
    Desumoylation of RNA polymerase III lies at the core of the Sumo stress response in yeast
    J Biol Chem, 294 (49), 18784-18795
    DOI 10.1074/jbc.RA119.009721, PubMed 31676685
  16. Palomo-Guerrero M, Fadó R, Casas M, Pérez-Montero M, Baena M, Helmer PO, Domínguez JL, Roig A, Serra D, Hayen H, Stenmark H, Raiborg C, Casals N (2019)
    Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
    Elife, 8
    DOI 10.7554/eLife.51063, PubMed 31868590
  17. Pandya AD, Jäger E, Bagheri Fam S, Höcherl A, Jäger A, Sincari V, Nyström B, Štěpánek P, Skotland T, Sandvig K, Hrubý M, Mælandsmo GM (2019)
    Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy
    Int J Nanomedicine, 14, 6269-6285
    DOI 10.2147/IJN.S208938, PubMed 31496685
  18. Prikrylova T, Robertson J, Ferrucci F, Konorska D, Aanes H, Manaf A, Zhang B, Vågbø CB, Kuśnierczyk A, Gilljam KM, Løvkvam-Køster C, Otterlei M, Dahl JA, Enserink J, Klungland A, Robertson AB (2019)
    5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
    Sci Rep, 9 (1), 11065
    DOI 10.1038/s41598-019-47528-3, PubMed 31363131
  19. Pölönen P, Jawahar Deen A, Leinonen HM, Jyrkkänen HK, Kuosmanen S, Mononen M, Jain A, Tuomainen T, Pasonen-Seppänen S, Hartikainen JM, Mannermaa A, Nykter M, Tavi P, Johansen T, Heinäniemi M, Levonen AL (2019)
    Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma
    Oncogene, 38 (50), 7473-7490
    DOI 10.1038/s41388-019-0956-6, PubMed 31444413
  20. Russell AE, Sneider A, Witwer KW, Bergese P, Bhattacharyya SN, Cocks A, Cocucci E, Erdbrügger U, Falcon-Perez JM, Freeman DW, Gallagher TM, Hu S, Huang Y, Jay SM, Kano SI, Lavieu G, Leszczynska A, Llorente AM, Lu Q, Mahairaki V, Muth DC, Noren Hooten N, Ostrowski M, Prada I, Sahoo S et al. (2019)
    Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop
    J Extracell Vesicles, 8 (1), 1684862
    DOI 10.1080/20013078.2019.1684862, PubMed 31762963
  21. Shoemaker CJ, Huang TQ, Weir NR, Polyakov NJ, Schultz SW, Denic V (2019)
    CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor
    PLoS Biol, 17 (4), e2007044
    DOI 10.1371/journal.pbio.2007044, PubMed 30933966
  22. Skjesol A, Yurchenko M, Bösl K, Gravastrand C, Nilsen KE, Grøvdal LM, Agliano F, Patane F, Lentini G, Kim H, Teti G, Kumar Sharma A, Kandasamy RK, Sporsheim B, Starheim KK, Golenbock DT, Stenmark H, McCaffrey M, Espevik T, Husebye H (2019)
    The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
    PLoS Pathog, 15 (3), e1007684
    DOI 10.1371/journal.ppat.1007684, PubMed 30883606
  23. Skotland T, Sandvig K (2019)
    The role of PS 18:0/18:1 in membrane function
    Nat Commun, 10 (1), 2752
    DOI 10.1038/s41467-019-10711-1, PubMed 31227693
  24. Sneeggen M, Pedersen NM, Campsteijn C, Haugsten EM, Stenmark H, Schink KO (2019)
    WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
    Nat Commun, 10 (1), 2850
    DOI 10.1038/s41467-019-10794-w, PubMed 31253801
  25. Sneeggen M, Schink KO, Stenmark H (2019)
    Tumor suppression by control of matrix metalloproteinase recycling
    Mol Cell Oncol, 6 (6), e1646606
    DOI 10.1080/23723556.2019.1646606, PubMed 31692886
  26. Sowa-Rogozińska N, Sominka H, Nowakowska-Gołacka J, Sandvig K, Słomińska-Wojewódzka M (2019)
    Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin
    Toxins (Basel), 11 (6)
    DOI 10.3390/toxins11060350, PubMed 31216687
  27. Szwed M, Sønstevold T, Øverbye A, Engedal N, Grallert B, Mørch Ý, Sulheim E, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2019)
    Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
    Nanotoxicology, 13 (6), 761-782
    DOI 10.1080/17435390.2019.1576238, PubMed 30760074
  28. Szybowska P, Kostas M, Wesche J, Wiedlocha A, Haugsten EM (2019)
    Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway
    Cells, 8 (6)
    DOI 10.3390/cells8060518, PubMed 31146385
  29. Tancini B, Buratta S, Sagini K, Costanzi E, Delo F, Urbanelli L, Emiliani C (2019)
    Insight into the Role of Extracellular Vesicles in Lysosomal Storage Disorders
    Genes (Basel), 10 (7)
    DOI 10.3390/genes10070510, PubMed 31284546
  30. Theodossiou TA, Ali M, Grigalavicius M, Grallert B, Dillard P, Schink KO, Olsen CE, Wälchli S, Inderberg EM, Kubin A, Peng Q, Berg K (2019)
    Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
    NPJ Breast Cancer, 5, 13
    DOI 10.1038/s41523-019-0108-8, PubMed 30993194
  31. Vietri M, Radulovic M, Stenmark H (2019)
    The many functions of ESCRTs
    Nat Rev Mol Cell Biol, 21 (1), 25-42
    DOI 10.1038/s41580-019-0177-4, PubMed 31705132
  32. Zakrzewska M, Opalinski L, Haugsten EM, Otlewski J, Wiedlocha A (2019)
    Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling
    Int J Mol Sci, 20 (8)
    DOI 10.3390/ijms20081826, PubMed 31013829
  33. Zhang B, Ayuda-Durán P, Piechaczyk L, Fløisand Y, Safont MM, Karlsen IT, Fandalyuk Z, Tadele D, van Mierlo P, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM (2019)
    GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
    Haematologica, 104 (5), e229
    DOI 10.3324/haematol.2019.220533, PubMed 31040234
  34. Zhen Y, Spangenberg H, Munson MJ, Brech A, Schink KO, Tan KW, Sørensen V, Wenzel EM, Radulovic M, Engedal N, Simonsen A, Raiborg C, Stenmark H (2019)
    ESCRT-mediated phagophore sealing during mitophagy
    Autophagy, 16 (5), 826-841
    DOI 10.1080/15548627.2019.1639301, PubMed 31366282

Publications 2018

  1. Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2018)
    Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft
    J Control Release, 293, 183-192
    DOI 10.1016/j.jconrel.2018.11.029, PubMed 30529259
  2. Herrera M, Llorens C, Rodríguez M, Herrera A, Ramos R, Gil B, Candia A, Larriba MJ, Garre P, Earl J, Rodríguez-Garrote M, Caldés T, Bonilla F, Carrato A, García-Barberán V, Peña C (2018)
    Differential distribution and enrichment of non-coding RNAs in exosomes from normal and Cancer-associated fibroblasts in colorectal cancer
    Mol Cancer, 17 (1), 114
    DOI 10.1186/s12943-018-0863-4, PubMed 30075793
  3. Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
    Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
    Nucleic Acids Res, 46 (22), 11698-11711
    DOI 10.1093/nar/gky846, PubMed 30247619
  4. Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
    Corrigendum: Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
    Nucleic Acids Res, 46 (22), 12188-12189
    DOI 10.1093/nar/gky1102, PubMed 30395271
  5. Hurem S, Gomes T, Brede DA, Mayer I, Lobert VH, Mutoloki S, Gutzkow KB, Teien HC, Oughton D, Aleström P, Lyche JL (2018)
    Gamma irradiation during gametogenesis in young adult zebrafish causes persistent genotoxicity and adverse reproductive effects
    Ecotoxicol Environ Saf, 154, 19-26
    DOI 10.1016/j.ecoenv.2018.02.031, PubMed 29453161
  6. Kostas M, Haugsten EM, Zhen Y, Sørensen V, Szybowska P, Fiorito E, Lorenz S, Jones N, de Souza GA, Wiedlocha A, Wesche J (2018)
    Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
    Mol Cell Proteomics, 17 (5), 850-870
    DOI 10.1074/mcp.RA117.000538, PubMed 29371290
  7. Kostas M, Lampart A, Bober J, Wiedlocha A, Tomala J, Krowarsch D, Otlewski J, Zakrzewska M (2018)
    Translocation of Exogenous FGF1 and FGF2 Protects the Cell against Apoptosis Independently of Receptor Activation
    J Mol Biol, 430 (21), 4087-4101
    DOI 10.1016/j.jmb.2018.08.004, PubMed 30099027
  8. Kruitwagen T, Chymkowitch P, Denoth-Lippuner A, Enserink J, Barral Y (2018)
    Centromeres License the Mitotic Condensation of Yeast Chromosome Arms
    Cell, 175 (3), 780-795.e15
    DOI 10.1016/j.cell.2018.09.012, PubMed 30318142
  9. Kumar S, Jain A, Farzam F, Jia J, Gu Y, Choi SW, Mudd MH, Claude-Taupin A, Wester MJ, Lidke KA, Rusten TE, Deretic V (2018)
    Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins
    J Cell Biol, 217 (3), 997-1013
    DOI 10.1083/jcb.201708039, PubMed 29420192
  10. Malerød L, Le Borgne R, Lie-Jensen A, Eikenes ÅH, Brech A, Liestøl K, Stenmark H, Haglund K (2018)
    Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics
    EMBO J, 37 (13)
    DOI 10.15252/embj.201797741, PubMed 29858227
  11. Mejlvang J, Olsvik H, Svenning S, Bruun JA, Abudu YP, Larsen KB, Brech A, Hansen TE, Brenne H, Hansen T, Stenmark H, Johansen T (2018)
    Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
    J Cell Biol, 217 (10), 3640-3655
    DOI 10.1083/jcb.201711002, PubMed 30018090
  12. Norum JH, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, Sørlie T (2018)
    The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology
    Biol Res, 51 (1), 3
    DOI 10.1186/s40659-017-0151-6, PubMed 29316982
  13. Nouri H, Monnier AF, Fossum-Raunehaug S, Maciag-Dorszynska M, Cabin-Flaman A, Képès F, Wegrzyn G, Szalewska-Palasz A, Norris V, Skarstad K, Janniere L (2018)
    Multiple links connect central carbon metabolism to DNA replication initiation and elongation in Bacillus subtilis
    DNA Res, 25 (6), 641-653
    DOI 10.1093/dnares/dsy031, PubMed 30256918
  14. Olsvik HL, Svenning S, Abudu YP, Brech A, Stenmark H, Johansen T, Mejlvang J (2018)
    Endosomal microautophagy is an integrated part of the autophagic response to amino acid starvation
    Autophagy, 15 (1), 182-183
    DOI 10.1080/15548627.2018.1532265, PubMed 30295124
  15. Osteikoetxea X, Benke M, Rodriguez M, Pálóczi K, Sódar BW, Szvicsek Z, Szabó-Taylor K, Vukman KV, Kittel Á, Wiener Z, Vékey K, Harsányi L, Szűcs Á, Turiák L, Buzás EI (2018)
    Detection and proteomic characterization of extracellular vesicles in human pancreatic juice
    Biochem Biophys Res Commun, 499 (1), 37-43
    DOI 10.1016/j.bbrc.2018.03.107, PubMed 29550476
  16. Popēna I, Ābols A, Saulīte L, Pleiko K, Zandberga E, Jēkabsons K, Endzeliņš E, Llorente A, Linē A, Riekstiņa U (2018)
    Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages
    Cell Commun Signal, 16 (1), 17
    DOI 10.1186/s12964-018-0229-y, PubMed 29690889
  17. Radulovic M, Schink KO, Wenzel EM, Nähse V, Bongiovanni A, Lafont F, Stenmark H (2018)
    ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival
    EMBO J, 37 (21)
    DOI 10.15252/embj.201899753, PubMed 30314966
  18. Radulovic M, Stenmark H (2018)
    ESCRTs in membrane sealing
    Biochem Soc Trans, 46 (4), 773-778
    DOI 10.1042/BST20170435, PubMed 29903934
  19. Sandvig K, Kavaliauskiene S, Skotland T (2018)
    Clathrin-independent endocytosis: an increasing degree of complexity
    Histochem Cell Biol, 150 (2), 107-118
    DOI 10.1007/s00418-018-1678-5, PubMed 29774430
  20. Skotland T, Hessvik NP, Sandvig K, Llorente A (2018)
    Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology
    J Lipid Res, 60 (1), 9-18
    DOI 10.1194/jlr.R084343, PubMed 30076207
  21. Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E et al. (2018)
    Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
    J Extracell Vesicles, 7 (1), 1535750
    DOI 10.1080/20013078.2018.1535750, PubMed 30637094
  22. Vietri M, Stenmark H (2018)
    Orchestrating Nuclear Envelope Sealing during Mitosis
    Dev Cell, 47 (5), 541-542
    DOI 10.1016/j.devcel.2018.11.020, PubMed 30513298
  23. Wenzel EM, Schultz SW, Schink KO, Pedersen NM, Nähse V, Carlson A, Brech A, Stenmark H, Raiborg C (2018)
    Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
    Nat Commun, 9 (1), 2932
    DOI 10.1038/s41467-018-05345-8, PubMed 30050131
  24. Weyergang A, Fremstedal AS, Skarpen E, Peng Q, Mohamedali KA, Eng MS, Cheung LH, Rosenblum MG, Waltenberger J, Berg K (2018)
    Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy
    J Control Release, 288, 161-172
    DOI 10.1016/j.jconrel.2018.09.005, PubMed 30217739
  25. Zhang B, Durán PA, Piechaczyk L, Fløisand Y, Safont MMS, Karlsen IT, Fandalyuk Z, Tadele D, Mierlo PV, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM, Bjørn Tore Gjertsen Group, Emmet McCormack Group (2018)
    GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
    Haematologica, Online ahead of print (in press) (Retracted)
    DOI 10.3324/haematol.2018.189399, PubMed 29748445
  26. Zhen Y, Haugsten EM, Singh SK, Wesche J (2018)
    Proximity Labeling by a Recombinant APEX2-FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4
    Biochemistry, 57 (26), 3807-3816
    DOI 10.1021/acs.biochem.8b00120, PubMed 29812912

Publications 2017

  1. Ailte I, Lingelem AB, Kvalvaag AS, Kavaliauskiene S, Brech A, Koster G, Dommersnes PG, Bergan J, Skotland T, Sandvig K (2017)
    Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
    Traffic, 18 (3), 176-191
    DOI 10.1111/tra.12468, PubMed 28067430
  2. Boye E, Skotland T, Østerud B, Nissen-Meyer J (2017)
    Doping and drug testing: Anti-doping work must be transparent and adhere to good scientific practices to ensure public trust
    EMBO Rep, 18 (3), 351-354
    DOI 10.15252/embr.201643540, PubMed 28167676
  3. Cambier S, Røgeberg M, Georgantzopoulou A, Serchi T, Karlsson C, Verhaegen S, Iversen TG, Guignard C, Kruszewski M, Hoffmann L, Audinot JN, Ropstad E, Gutleb AC (2017)
    Fate and effects of silver nanoparticles on early life-stage development of zebrafish (Danio rerio) in comparison to silver nitrate
    Sci Total Environ, 610-611, 972-982
    DOI 10.1016/j.scitotenv.2017.08.115, PubMed 28838034
  4. Chymkowitch P, Enserink JM (2017)
    Regulation of tRNA synthesis by posttranslational modifications of RNA polymerase III subunits
    Biochim Biophys Acta Gene Regul Mech, 1861 (4), 310-319
    DOI 10.1016/j.bbagrm.2017.11.001, PubMed 29127063
  5. Chymkowitch P, Nguéa P A, Aanes H, Robertson J, Klungland A, Enserink JM (2017)
    TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity
    Proc Natl Acad Sci U S A, 114 (5), 1039-1044
    DOI 10.1073/pnas.1615093114, PubMed 28096404
  6. Endzeliņš E, Berger A, Melne V, Bajo-Santos C, Soboļevska K, Ābols A, Rodriguez M, Šantare D, Rudņickiha A, Lietuvietis V, Llorente A, Linē A (2017)
    Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients
    BMC Cancer, 17 (1), 730
    DOI 10.1186/s12885-017-3737-z, PubMed 29121858
  7. Enserink J, Nguéa P A, Chymkowitch P (2017)
    Anabolic transcription: Secrets of the sumo diet
    Cell Cycle, 16 (7), 593-594
    DOI 10.1080/15384101.2017.1294945, PubMed 28278057
  8. Enserink JM (2017)
    Regulation of Cellular Processes by SUMO: Understudied Topics
    Adv Exp Med Biol, 963, 89-97
    DOI 10.1007/978-3-319-50044-7_5, PubMed 28197907
  9. Enserink JM (2017)
    Sumo during stress: When transcription takes a pause (comment on DOI.10.1002/bies.201600263)
    Bioessays, 39 (6)
    DOI 10.1002/bies.201700065, PubMed 28464310
  10. Flåtten I, Helgesen E, Pedersen IB, Waldminghaus T, Rothe C, Taipale R, Johnsen L, Skarstad K (2017)
    Phenotypes of dnaXE145A Mutant Cells Indicate that the Escherichia coli Clamp Loader Has a Role in the Restart of Stalled Replication Forks
    J Bacteriol, 199 (24)
    DOI 10.1128/JB.00412-17, PubMed 28947673
  11. Fosdahl AM, Dietrich M, Schink KO, Malik MS, Skeie M, Bertelsen V, Stang E (2017)
    ErbB3 interacts with Hrs and is sorted to lysosomes for degradation
    Biochim Biophys Acta Mol Cell Res, 1864 (12), 2241-2252
    DOI 10.1016/j.bbamcr.2017.08.011, PubMed 28867611
  12. Hardes K, Ivanova T, Thaa B, McInerney GM, Klokk TI, Sandvig K, Künzel S, Lindberg I, Steinmetzer T (2017)
    Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin
    ChemMedChem, 12 (8), 613-620
    DOI 10.1002/cmdc.201700108, PubMed 28334511
  13. Hessvik NP, Llorente A (2017)
    Current knowledge on exosome biogenesis and release
    Cell Mol Life Sci, 75 (2), 193-208
    DOI 10.1007/s00018-017-2595-9, PubMed 28733901
  14. Hong Z, Pedersen NM, Wang L, Torgersen ML, Stenmark H, Raiborg C (2017)
    PtdIns3P controls mTORC1 signaling through lysosomal positioning
    J Cell Biol, 216 (12), 4217-4233
    DOI 10.1083/jcb.201611073, PubMed 29030394
  15. Katheder NS, Khezri R, O'Farrell F, Schultz SW, Jain A, Rahman MM, Schink KO, Theodossiou TA, Johansen T, Juhász G, Bilder D, Brech A, Stenmark H, Rusten TE (2017)
    Microenvironmental autophagy promotes tumour growth
    Nature, 541 (7637), 417-420
    DOI 10.1038/nature20815, PubMed 28077876
  16. Katheder NS, Rusten TE (2017)
    Microenvironment and tumors-a nurturing relationship
    Autophagy, 13 (7), 1241-1243
    DOI 10.1080/15548627.2017.1310361, PubMed 28632995
  17. Kavaliauskiene S, Dyve Lingelem AB, Skotland T, Sandvig K (2017)
    Protection against Shiga Toxins
    Toxins (Basel), 9 (2)
    DOI 10.3390/toxins9020044, PubMed 28165371
  18. Krzyscik MA, Zakrzewska M, Sørensen V, Sokolowska-Wedzina A, Lobocki M, Swiderska KW, Krowarsch D, Wiedlocha A, Otlewski J (2017)
    Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors
    ACS Omega, 2 (7), 3792-3805
    DOI 10.1021/acsomega.7b00116, PubMed 30023704
  19. Labieniec-Watala M, Szwed M, Hertel J, Wisnik E (2017)
    Low Concentrations of Cationic PAMAM Dendrimers Affect Lymphocyte Respiration in In vitro Studies
    Curr Pharm Biotechnol, 18 (2), 150-157
    DOI 10.2174/1389201017666161229153018, PubMed 28034293
  20. Lång A, Eriksson J, Schink KO, Lång E, Blicher P, Połeć A, Brech A, Dalhus B, Bøe SO (2017)
    Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites
    Nucleus, 8 (4), 404-420
    DOI 10.1080/19491034.2017.1306161, PubMed 28402725
  21. Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V (2017)
    Correction: TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
    J Cell Sci, 130 (6), 1194
    DOI 10.1242/jcs.202499, PubMed 28298613
  22. Manna D, Pust S, Torgersen ML, Cordara G, Künzler M, Krengel U, Sandvig K (2017)
    Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis
    PLoS One, 12 (1), e0170716
    DOI 10.1371/journal.pone.0170716, PubMed 28114329
  23. O'Farrell F, Lobert VH, Sneeggen M, Jain A, Katheder NS, Wenzel EM, Schultz SW, Tan KW, Brech A, Stenmark H, Rusten TE (2017)
    Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation
    Nat Cell Biol, 19 (12), 1412-1423
    DOI 10.1038/ncb3631, PubMed 29084199
  24. Olsen CE, Weyergang A, Edwards VT, Berg K, Brech A, Weisheit S, Høgset A, Selbo PK (2017)
    Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
    Biochem Pharmacol, 144, 63-77
    DOI 10.1016/j.bcp.2017.08.002, PubMed 28784290
  25. Pathan M, Keerthikumar S, Chisanga D, Alessandro R, Ang CS, Askenase P, Batagov AO, Benito-Martin A, Camussi G, Clayton A, Collino F, Di Vizio D, Falcon-Perez JM, Fonseca P, Fonseka P, Fontana S, Gho YS, Hendrix A, Hoen EN, Iraci N, Kastaniegaard K, Kislinger T, Kowal J, Kurochkin IV, Leonardi T et al. (2017)
    A novel community driven software for functional enrichment analysis of extracellular vesicles data
    J Extracell Vesicles, 6 (1), 1321455
    DOI 10.1080/20013078.2017.1321455, PubMed 28717418
  26. Pedersen IB, Helgesen E, Flåtten I, Fossum-Raunehaug S, Skarstad K (2017)
    SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms
    Nucleic Acids Res, 45 (11), 6471-6485
    DOI 10.1093/nar/gkx263, PubMed 28407100
  27. Pietarinen PO, Eide CA, Ayuda-Durán P, Potdar S, Kuusanmäki H, Andersson EI, Mpindi JP, Pemovska T, Kontro M, Heckman CA, Kallioniemi O, Wennerberg K, Hjorth-Hansen H, Druker BJ, Enserink JM, Tyner JW, Mustjoki S, Porkka K (2017)
    Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors
    Oncotarget, 8 (14), 22606-22615
    DOI 10.18632/oncotarget.15146, PubMed 28186983
  28. Rahman MM, Franch-Marro X, Maestro JL, Martin D, Casali A (2017)
    Local Juvenile Hormone activity regulates gut homeostasis and tumor growth in adult Drosophila
    Sci Rep, 7 (1), 11677
    DOI 10.1038/s41598-017-11199-9, PubMed 28916802
  29. Raiborg C, Schink KO, Stenmark H (2017)
    Suppressing mTORC1 on the lysosome
    EMBO J, 36 (13), 1809-1810
    DOI 10.15252/embj.201797469, PubMed 28623241
  30. Sadovska L, Zandberga E, Sagini K, Jēkabsons K, Riekstiņa U, Kalniņa Z, Llorente A, Linē A (2017)
    A novel 3D heterotypic spheroid model for studying extracellular vesicle-mediated tumour and immune cell communication
    Biochem Biophys Res Commun, 495 (2), 1930-1935
    DOI 10.1016/j.bbrc.2017.12.072, PubMed 29248729
  31. Simm R, Kvalvaag AS, van Deurs B, Lindbäck T, Sandvig K (2017)
    Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network
    Exp Cell Res, 357 (1), 67-78
    DOI 10.1016/j.yexcr.2017.04.025, PubMed 28450044
  32. Skotland T (2017)
    Injection of nanoparticles into cloven-hoof animals: Asking for trouble
    Theranostics, 7 (19), 4877-4878
    DOI 10.7150/thno.22420, PubMed 29187910
  33. Skotland T, Sandvig K, Llorente A (2017)
    Lipids in exosomes: Current knowledge and the way forward
    Prog Lipid Res, 66, 30-41
    DOI 10.1016/j.plipres.2017.03.001, PubMed 28342835
  34. Sulheim E, Iversen TG, To Nakstad V, Klinkenberg G, Sletta H, Schmid R, Hatletveit AR, Wågbø AM, Sundan A, Skotland T, Sandvig K, Mørch Ý (2017)
    Cytotoxicity of Poly(Alkyl Cyanoacrylate) Nanoparticles
    Int J Mol Sci, 18 (11)
    DOI 10.3390/ijms18112454, PubMed 29156588
  35. Søreng K, Knævelsrud H, Holland P, Simonsen A (2017)
    HS1BP3 inhibits autophagy by regulation of PLD1
    Autophagy, 13 (5), 985-986
    DOI 10.1080/15548627.2017.1291483, PubMed 28318354
  36. Taubenschmid J, Stadlmann J, Jost M, Klokk TI, Rillahan CD, Leibbrandt A, Mechtler K, Paulson JC, Jude J, Zuber J, Sandvig K, Elling U, Marquardt T, Thiel C, Koerner C, Penninger JM (2017)
    A vital sugar code for ricin toxicity
    Cell Res, 27 (11), 1351-1364
    DOI 10.1038/cr.2017.116, PubMed 28925387
  37. Thorvaldsen TE (2017)
    Targeting Tankyrase to Fight WNT-dependent Tumours
    Basic Clin Pharmacol Toxicol, 121 (2), 81-88
    DOI 10.1111/bcpt.12786, PubMed 28371398
  38. Thorvaldsen TE, Pedersen NM, Wenzel EM, Stenmark H (2017)
    Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation
    PLoS One, 12 (1), e0170508
    DOI 10.1371/journal.pone.0170508, PubMed 28107521
  39. Totland MZ, Bergsland CH, Fykerud TA, Knudsen LM, Rasmussen NL, Eide PW, Yohannes Z, Sørensen V, Brech A, Lothe RA, Leithe E (2017)
    The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions
    J Cell Sci, 130 (17), 2867-2882
    DOI 10.1242/jcs.202408, PubMed 28733455
  40. Tusco R, Jacomin AC, Jain A, Penman BS, Larsen KB, Johansen T, Nezis IP (2017)
    Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
    Nat Commun, 8 (1), 1264
    DOI 10.1038/s41467-017-01287-9, PubMed 29097655
  41. Vestad B, Llorente A, Neurauter A, Phuyal S, Kierulf B, Kierulf P, Skotland T, Sandvig K, Haug KBF, Øvstebø R (2017)
    Size and concentration analyses of extracellular vesicles by nanoparticle tracking analysis: a variation study
    J Extracell Vesicles, 6 (1), 1344087
    DOI 10.1080/20013078.2017.1344087, PubMed 28804597
  42. Zimmermann C, Garcia I, Omerzu M, Chymkowitch P, Zhang B, Enserink JM (2017)
    Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28
    G3 (Bethesda), 7 (6), 1753-1766
    DOI 10.1534/g3.117.042317, PubMed 28428242
  43. Øverbye A, Holsæter AM, Markus F, Škalko-Basnet N, Iversen TG, Torgersen ML, Sønstevold T, Engebraaten O, Flatmark K, Mælandsmo GM, Skotland T, Sandvig K (2017)
    Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide
    Oncotarget, 8 (44), 76921-76934
    DOI 10.18632/oncotarget.20217, PubMed 29100358

Publications 2016

  1. Ailte I, Lingelem AB, Kavaliauskiene S, Bergan J, Kvalvaag AS, Myrann AG, Skotland T, Sandvig K (2016)
    Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding
    Sci Rep, 6, 30336
    DOI 10.1038/srep30336, PubMed 27458147
  2. Asp N, Kvalvaag A, Sandvig K, Pust S (2016)
    Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins
    Oncotarget, 7 (18), 25443-60
    DOI 10.18632/oncotarget.8327, PubMed 27029001
  3. Bober J, Olsnes S, Kostas M, Bogacz M, Zakrzewska M, Otlewski J (2016)
    Identification of new FGF1 binding partners-Implications for its intracellular function
    IUBMB Life, 68 (3), 242-51
    DOI 10.1002/iub.1480, PubMed 26840910
  4. Campsteijn C, Vietri M, Stenmark H (2016)
    Novel ESCRT functions in cell biology: spiraling out of control?
    Curr Opin Cell Biol, 41, 1-8
    DOI 10.1016/j.ceb.2016.03.008, PubMed 27031044
  5. Christ L, Raiborg C, Wenzel EM, Campsteijn C, Stenmark H (2016)
    Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery
    Trends Biochem Sci, 42 (1), 42-56
    DOI 10.1016/j.tibs.2016.08.016, PubMed 27669649
  6. Christ L, Wenzel EM, Liestøl K, Raiborg C, Campsteijn C, Stenmark H (2016)
    ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission
    J Cell Biol, 212 (5), 499-513
    DOI 10.1083/jcb.201507009, PubMed 26929449
  7. Cordara G, van Eerde A, Grahn EM, Winter HC, Goldstein IJ, Krengel U (2016)
    An Unusual Member of the Papain Superfamily: Mapping the Catalytic Cleft of the Marasmius oreades agglutinin (MOA) with a Caspase Inhibitor
    PLoS One, 11 (2), e0149407
    DOI 10.1371/journal.pone.0149407, PubMed 26901797
  8. Endzeliņš E, Melne V, Kalniņa Z, Lietuvietis V, Riekstiņa U, Llorente A, Linē A (2016)
    Diagnostic, prognostic and predictive value of cell-free miRNAs in prostate cancer: a systematic review
    Mol Cancer, 15 (1), 41
    DOI 10.1186/s12943-016-0523-5, PubMed 27189160
  9. Fais S, O'Driscoll L, Borras FE, Buzas E, Camussi G, Cappello F, Carvalho J, Cordeiro da Silva A, Del Portillo H, El Andaloussi S, Ficko Trček T, Furlan R, Hendrix A, Gursel I, Kralj-Iglic V, Kaeffer B, Kosanovic M, Lekka ME, Lipps G, Logozzi M, Marcilla A, Sammar M, Llorente A, Nazarenko I, Oliveira C et al. (2016)
    Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine
    ACS Nano, 10 (4), 3886-99
    DOI 10.1021/acsnano.5b08015, PubMed 26978483
  10. Fykerud TA, Knudsen LM, Totland MZ, Sørensen V, Dahal-Koirala S, Lothe RA, Brech A, Leithe E (2016)
    Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding
    Cell Cycle, 15 (21), 2943-2957
    DOI 10.1080/15384101.2016.1231280, PubMed 27625181
  11. Halsne R, Tandberg JI, Lobert VH, Østby GC, Thoen E, Ropstad E, Verhaegen S (2016)
    Effects of perfluorinated alkyl acids on cellular responses of MCF-10A mammary epithelial cells in monolayers and on acini formation in vitro
    Toxicol Lett, 259, 95-107
    DOI 10.1016/j.toxlet.2016.08.004, PubMed 27511595
  12. Haugsten EM, Sørensen V, Kunova Bosakova M, de Souza GA, Krejci P, Wiedlocha A, Wesche J (2016)
    Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport
    J Proteome Res, 15 (10), 3841-3855
    DOI 10.1021/acs.jproteome.6b00652, PubMed 27615514
  13. Helgesen E, Fossum-Raunehaug S, Skarstad K (2016)
    Lack of the H-NS Protein Results in Extended and Aberrantly Positioned DNA during Chromosome Replication and Segregation in Escherichia coli
    J Bacteriol, 198 (8), 1305-16
    DOI 10.1128/JB.00919-15, PubMed 26858102
  14. Herrera C, Klokk TI, Cole R, Sandvig K, Mantis NJ (2016)
    A Bispecific Antibody Promotes Aggregation of Ricin Toxin on Cell Surfaces and Alters Dynamics of Toxin Internalization and Trafficking
    PLoS One, 11 (6), e0156893
    DOI 10.1371/journal.pone.0156893, PubMed 27300140
  15. Hessvik NP, Øverbye A, Brech A, Torgersen ML, Jakobsen IS, Sandvig K, Llorente A (2016)
    PIKfyve inhibition increases exosome release and induces secretory autophagy
    Cell Mol Life Sci, 73 (24), 4717-4737
    DOI 10.1007/s00018-016-2309-8, PubMed 27438886
  16. Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A (2016)
    HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
    Nat Commun, 7, 13889
    DOI 10.1038/ncomms13889, PubMed 28004827
  17. Kavaliauskiene S, Torgersen ML, Lingelem AB, Klokk TI, Lintonen T, Simolin H, Ekroos K, Skotland T, Sandvig K (2016)
    Cellular effects of fluorodeoxyglucose: Global changes in the lipidome and alteration in intracellular transport
    Oncotarget, 7 (48), 79885-79900
    DOI 10.18632/oncotarget.13089, PubMed 27829218
  18. Li Y, Hessvik NP, Danbolt NC, Holen T (2016)
    A large-scale quantitative EM study on activation of olfactory glands shows no effect of cholinergic agents
    Microscopy (Oxf), 65 (5), 438-443
    DOI 10.1093/jmicro/dfw028, PubMed 27460022
  19. Lie-Jensen A, Haglund K (2016)
    Antibody Staining in Drosophila Germaria
    Methods Mol Biol, 1457, 19-33
    DOI 10.1007/978-1-4939-3795-0_3, PubMed 27557571
  20. Lobert VH, Mouradov D, Heath JK (2016)
    Focusing the Spotlight on the Zebrafish Intestine to Illuminate Mechanisms of Colorectal Cancer
    Adv Exp Med Biol, 916, 411-37
    DOI 10.1007/978-3-319-30654-4_18, PubMed 27165364
  21. Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M (2016)
    ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors
    Sci Signal, 9 (411), ra8
    DOI 10.1126/scisignal.aad0848, PubMed 26787452
  22. Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V (2016)
    TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
    J Cell Sci, 129 (19), 3562-3573
    DOI 10.1242/jcs.190017, PubMed 27562068
  23. Nähse V, Christ L, Stenmark H, Campsteijn C (2016)
    The Abscission Checkpoint: Making It to the Final Cut
    Trends Cell Biol, 27 (1), 1-11
    DOI 10.1016/j.tcb.2016.10.001, PubMed 27810282
  24. Pedersen NM, Thorvaldsen TE, Schultz SW, Wenzel EM, Stenmark H (2016)
    Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity
    PLoS One, 11 (8), e0160507
    DOI 10.1371/journal.pone.0160507, PubMed 27482906
  25. Puvirajesinghe TM, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, Sebbagh M, Lopez M, Brech A, Finetti P, Charafe-Jauffret E, Chaffanet M, Castellano R, Restouin A, Marchetto S, Collette Y, Gonçalvès A, Macara I, Birnbaum D, Kodjabachian L, Johansen T, Borg JP (2016)
    Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer
    Nat Commun, 7, 10318
    DOI 10.1038/ncomms10318, PubMed 26754771
  26. Raiborg C, Stenmark H (2016)
    Plasma membrane repairs by small GTPase Rab3a
    J Cell Biol, 213 (6), 613-5
    DOI 10.1083/jcb.201606006, PubMed 27325788
  27. Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
    Phosphoinositides in membrane contact sites
    Biochem Soc Trans, 44 (2), 425-30
    DOI 10.1042/BST20150190, PubMed 27068950
  28. Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
    ER-endosome contact sites in endosome positioning and protrusion outgrowth
    Biochem Soc Trans, 44 (2), 441-6
    DOI 10.1042/BST20150246, PubMed 27068952
  29. Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2016)
    Data including GROMACS input files for atomistic molecular dynamics simulations of mixed, asymmetric bilayers including molecular topologies, equilibrated structures, and force field for lipids compatible with OPLS-AA parameters
    Data Brief, 7, 1171-1174
    DOI 10.1016/j.dib.2016.03.067, PubMed 27761499
  30. Schink KO, Tan KW, Stenmark H (2016)
    Phosphoinositides in Control of Membrane Dynamics
    Annu Rev Cell Dev Biol, 32, 143-171
    DOI 10.1146/annurev-cellbio-111315-125349, PubMed 27576122
  31. Schmid MR, Anderl I, Vo HT, Valanne S, Yang H, Kronhamn J, Rämet M, Rusten TE, Hultmark D (2016)
    Genetic Screen in Drosophila Larvae Links ird1 Function to Toll Signaling in the Fat Body and Hemocyte Motility
    PLoS One, 11 (7), e0159473
    DOI 10.1371/journal.pone.0159473, PubMed 27467079
  32. Skotland T (2016)
    How organizers of scientific meetings and journal editors could facilitate transfer of nanomedicine into the clinic
    Eur. J. Nanomed., 8 (1), 61-63
    DOI 10.1515/ejnm-2015-0048
  33. Skotland T, Ekroos K, Kauhanen D, Simolin H, Seierstad T, Berge V, Sandvig K, Llorente A (2016)
    Molecular lipid species in urinary exosomes as potential prostate cancer biomarkers
    Eur J Cancer, 70, 122-132
    DOI 10.1016/j.ejca.2016.10.011, PubMed 27914242
  34. Skotland T, Ekroos K, Kavaliauskiene S, Bergan J, Kauhanen D, Lintonen T, Sandvig K (2016)
    Determining the Turnover of Glycosphingolipid Species by Stable-Isotope Tracer Lipidomics
    J Mol Biol, 428 (24 Pt A), 4856-4866
    DOI 10.1016/j.jmb.2016.06.013, PubMed 27363608
  35. Sundvold H, Sundvold-Gjerstad V, Malerød-Fjeld H, Haglund K, Stenmark H, Malerød L (2016)
    Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow
    Cell Cycle, 15 (5), 628-43
    DOI 10.1080/15384101.2016.1146834, PubMed 27104745
  36. Szymanska M, Fosdahl AM, Raiborg C, Dietrich M, Liestøl K, Stang E, Bertelsen V (2016)
    Interaction with epsin 1 regulates the constitutive clathrin-dependent internalization of ErbB3
    Biochim Biophys Acta, 1863 (6 Pt A), 1179-88
    DOI 10.1016/j.bbamcr.2016.03.011, PubMed 26975582
  37. Tesikova M, Dezitter X, Nenseth HZ, Klokk TI, Mueller F, Hager GL, Saatcioglu F (2016)
    Divergent Binding and Transactivation by Two Related Steroid Receptors at the Same Response Element
    J Biol Chem, 291 (22), 11899-910
    DOI 10.1074/jbc.M115.684480, PubMed 27056330
  38. Torgersen ML, Klokk TI, Kavaliauskiene S, Klose C, Simons K, Skotland T, Sandvig K (2016)
    The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport
    Oncotarget, 7 (52), 86871-86888
    DOI 10.18632/oncotarget.13508, PubMed 27894086
  39. Vietri M, Stenmark H, Campsteijn C (2016)
    Closing a gap in the nuclear envelope
    Curr Opin Cell Biol, 40, 90-97
    DOI 10.1016/j.ceb.2016.03.001, PubMed 27016712
  40. Wang L, Skotland T, Berge V, Sandvig K, Llorente A (2016)
    Exosomal proteins as prostate cancer biomarkers in urine: From mass spectrometry discovery to immunoassay-based validation
    Eur J Pharm Sci, 98, 80-85
    DOI 10.1016/j.ejps.2016.09.023, PubMed 27664330
  41. Yermakova A, Klokk TI, O'Hara JM, Cole R, Sandvig K, Mantis NJ (2016)
    Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin's Enzymatic Subunit Interfere with Intracellular Toxin Transport
    Sci Rep, 6, 22721
    DOI 10.1038/srep22721, PubMed 26949061

Publications 2015

  1. Bauereiss A, Welzel O, Jung J, Grosse-Holz S, Lelental N, Lewczuk P, Wenzel EM, Kornhuber J, Groemer TW (2015)
    Surface Trafficking of APP and BACE in Live Cells
    Traffic, 16 (6), 655-75
    DOI 10.1111/tra.12270, PubMed 25712587
  2. Buchtova M, Chaloupkova R, Zakrzewska M, Vesela I, Cela P, Barathova J, Gudernova I, Zajickova R, Trantirek L, Martin J, Kostas M, Otlewski J, Damborsky J, Kozubik A, Wiedlocha A, Krejci P (2015)
    Instability restricts signaling of multiple fibroblast growth factors
    Cell Mol Life Sci, 72 (12), 2445-59
    DOI 10.1007/s00018-015-1856-8, PubMed 25854632
  3. Bull-Hansen B, Berstad MB, Berg K, Cao Y, Skarpen E, Fremstedal AS, Rosenblum MG, Peng Q, Weyergang A (2015)
    Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer
    Oncotarget, 6 (14), 12436-51
    DOI 10.18632/oncotarget.3814, PubMed 26002552
  4. Drießen S, Berleth N, Friesen O, Löffler AS, Böhler P, Hieke N, Stuhldreier F, Peter C, Schink KO, Schultz SW, Stenmark H, Holland P, Simonsen A, Wesselborg S, Stork B (2015)
    Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy
    Autophagy, 11 (9), 1458-70
    DOI 10.1080/15548627.2015.1067359, PubMed 26207339
  5. Dyve Lingelem AB, Hjelseth IA, Simm R, Torgersen ML, Sandvig K (2015)
    Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells
    PLoS One, 10 (5), e0129214
    DOI 10.1371/journal.pone.0129214, PubMed 26017782
  6. Egeland EV, Boye K, Pettersen SJ, Haugen MH, Øyjord T, Malerød L, Flatmark K, Mælandsmo GM (2015)
    Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes
    Clin Exp Metastasis, 32 (8), 755-67
    DOI 10.1007/s10585-015-9742-1, PubMed 26349943
  7. Eikenes ÅH, Malerød L, Christensen AL, Steen CB, Mathieu J, Nezis IP, Liestøl K, Huynh JR, Stenmark H, Haglund K (2015)
    ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo
    PLoS Genet, 11 (1), e1004904
    DOI 10.1371/journal.pgen.1004904, PubMed 25635693
  8. Eikenes ÅH, Malerød L, Lie-Jensen A, Sem Wegner C, Brech A, Liestøl K, Stenmark H, Haglund K (2015)
    Src64 controls a novel actin network required for proper ring canal formation in the Drosophila male germline
    Development, 142 (23), 4107-18
    DOI 10.1242/dev.124370, PubMed 26628094
  9. Eriksen AB, Torgersen ML, Holm KL, Abrahamsen G, Spurkland A, Moskaug JØ, Simonsen A, Blomhoff HK (2015)
    Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy
    Autophagy, 11 (3), 460-71
    DOI 10.1080/15548627.2015.1009797, PubMed 25749095
  10. Flåtten I, Fossum-Raunehaug S, Taipale R, Martinsen S, Skarstad K (2015)
    The DnaA Protein Is Not the Limiting Factor for Initiation of Replication in Escherichia coli
    PLoS Genet, 11 (6), e1005276
    DOI 10.1371/journal.pgen.1005276, PubMed 26047361
  11. Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T (2015)
    Novel Furin Inhibitors with Potent Anti-infectious Activity
    ChemMedChem, 10 (7), 1218-31
    DOI 10.1002/cmdc.201500103, PubMed 25974265
  12. Helgesen E, Fossum-Raunehaug S, Sætre F, Schink KO, Skarstad K (2015)
    Dynamic Escherichia coli SeqA complexes organize the newly replicated DNA at a considerable distance from the replisome
    Nucleic Acids Res, 43 (5), 2730-43
    DOI 10.1093/nar/gkv146, PubMed 25722374
  13. Jain A, Rusten TE, Katheder N, Elvenes J, Bruun JA, Sjøttem E, Lamark T, Johansen T (2015)
    p62/Sequestosome-1, Autophagy-related Gene 8, and Autophagy in Drosophila Are Regulated by Nuclear Factor Erythroid 2-related Factor 2 (NRF2), Independent of Transcription Factor TFEB
    J Biol Chem, 290 (24), 14945-62
    DOI 10.1074/jbc.M115.656116, PubMed 25931115
  14. Kavaliauskiene S, Skotland T, Sylvänne T, Simolin H, Klokk TI, Torgersen ML, Lingelem AB, Simm R, Ekroos K, Sandvig K (2015)
    Novel actions of 2-deoxy-D-glucose: protection against Shiga toxins and changes in cellular lipids
    Biochem J, 470 (1), 23-37
    DOI 10.1042/BJ20141562, PubMed 26251444
  15. Klokk TI, Kavaliauskiene S, Sandvig K (2015)
    Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic
    Cell Mol Life Sci, 73 (6), 1301-16
    DOI 10.1007/s00018-015-2049-1, PubMed 26407609
  16. Kymre L, Simm R, Skotland T, Sandvig K (2015)
    Different roles of the C-terminal end of Stx1A and Stx2A for AB5 complex integrity and retrograde transport of Stx in HeLa cells
    Pathog Dis, 73 (9), ftv083
    DOI 10.1093/femspd/ftv083, PubMed 26443836
  17. Le Guyon S, Simm R, Rehn M, Römling U (2015)
    Dissecting the cyclic di-guanylate monophosphate signalling network regulating motility in Salmonella enterica serovar Typhimurium
    Environ Microbiol, 17 (4), 1310-20
    DOI 10.1111/1462-2920.12580, PubMed 25059628
  18. Raiborg C, Wenzel EM, Pedersen NM, Olsvik H, Schink KO, Schultz SW, Vietri M, Nisi V, Bucci C, Brech A, Johansen T, Stenmark H (2015)
    Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth
    Nature, 520 (7546), 234-8
    DOI 10.1038/nature14359, PubMed 25855459
  19. Raiborg C, Wenzel EM, Stenmark H (2015)
    ER-endosome contact sites: molecular compositions and functions
    EMBO J, 34 (14), 1848-58
    DOI 10.15252/embj.201591481, PubMed 26041457
  20. Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2015)
    Interdigitation of long-chain sphingomyelin induces coupling of membrane leaflets in a cholesterol dependent manner
    Biochim Biophys Acta, 1858 (2), 281-8
    DOI 10.1016/j.bbamem.2015.12.003, PubMed 26654782
  21. Skotland T, Iversen TG, Torgersen ML, Sandvig K (2015)
    Cell-penetrating peptides: possibilities and challenges for drug delivery in vitro and in vivo
    Molecules, 20 (7), 13313-23
    DOI 10.3390/molecules200713313, PubMed 26205056
  22. Słomińska-Wojewódzka M, Sandvig K (2015)
    The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation
    Molecules, 20 (6), 9816-46
    DOI 10.3390/molecules20069816, PubMed 26023941
  23. Sokołowska I, Piłka ES, Sandvig K, Węgrzyn G, Słomińska-Wojewódzka M (2015)
    Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells
    BMC Cell Biol, 16, 1
    DOI 10.1186/s12860-015-0047-7, PubMed 25655076
  24. Sternemalm J, Geimer S, Frikstad KA, Schink KO, Stokke T, Patzke S (2015)
    CSPP-L Associates with the Desmosome of Polarized Epithelial Cells and Is Required for Normal Spheroid Formation
    PLoS One, 10 (8), e0134789
    DOI 10.1371/journal.pone.0134789, PubMed 26241740
  25. Szalai P, Hagen LK, Sætre F, Luhr M, Sponheim M, Øverbye A, Mills IG, Seglen PO, Engedal N (2015)
    Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs
    Exp Cell Res, 333 (1), 21-38
    DOI 10.1016/j.yexcr.2015.02.003, PubMed 25684710
  26. Theodossiou TA, Wälchli S, Olsen CE, Skarpen E, Berg K (2015)
    Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
    ACS Chem Biol, 11 (1), 251-62
    DOI 10.1021/acschembio.5b00734, PubMed 26569462
  27. Thorvaldsen TE, Pedersen NM, Wenzel EM, Schultz SW, Brech A, Liestøl K, Waaler J, Krauss S, Stenmark H (2015)
    Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes
    Mol Cancer Res, 13 (11), 1487-501
    DOI 10.1158/1541-7786.MCR-15-0125, PubMed 26124443
  28. Vietri M, Schink KO, Campsteijn C, Wegner CS, Schultz SW, Christ L, Thoresen SB, Brech A, Raiborg C, Stenmark H (2015)
    Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing
    Nature, 522 (7555), 231-5
    DOI 10.1038/nature14408, PubMed 26040712
  29. Wendel T, Zhen Y, Suo Z, Bruheim S, Wiedlocha A (2015)
    The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo
    Exp Cell Res, 340 (2), 220-6
    DOI 10.1016/j.yexcr.2015.12.017, PubMed 26748184
  30. Yáñez-Mó M, Siljander PR, Andreu Z, Zavec AB, Borràs FE, Buzas EI, Buzas K, Casal E, Cappello F, Carvalho J, Colás E, Cordeiro-da Silva A, Fais S, Falcon-Perez JM, Ghobrial IM, Giebel B, Gimona M, Graner M, Gursel I, Gursel M, Heegaard NH, Hendrix A, Kierulf P, Kokubun K, Kosanovic M et al. (2015)
    Biological properties of extracellular vesicles and their physiological functions
    J Extracell Vesicles, 4, 27066
    DOI 10.3402/jev.v4.27066, PubMed 25979354
  31. Zhen Y, Stenmark H (2015)
    Cellular functions of Rab GTPases at a glance
    J Cell Sci, 128 (17), 3171-6
    DOI 10.1242/jcs.166074, PubMed 26272922
  32. Øverbye A, Skotland T, Koehler CJ, Thiede B, Seierstad T, Berge V, Sandvig K, Llorente A (2015)
    Identification of prostate cancer biomarkers in urinary exosomes
    Oncotarget, 6 (30), 30357-76
    DOI 10.18632/oncotarget.4851, PubMed 26196085
  33. Øvrebø JI, Campsteijn C, Kourtesis I, Hausen H, Raasholm M, Thompson EM (2015)
    Functional specialization of chordate CDK1 paralogs during oogenic meiosis
    Cell Cycle, 14 (6), 880-93
    DOI 10.1080/15384101.2015.1006000, PubMed 25714331

Publications 2014

  1. Anda S, Boye E, Grallert B (2014)
    Cell-cycle analyses using thymidine analogues in fission yeast
    PLoS One, 9 (2), e88629
    DOI 10.1371/journal.pone.0088629, PubMed 24551125
  2. Asp N, Pust S, Sandvig K (2014)
    Flotillin depletion affects ErbB protein levels in different human breast cancer cells
    Biochim Biophys Acta, 1843 (9), 1987-96
    DOI 10.1016/j.bbamcr.2014.04.013, PubMed 24747692
  3. Bergan J, Skotland T, Lingelem AB, Simm R, Spilsberg B, Lindbäck T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2014)
    The ether lipid precursor hexadecylglycerol protects against Shiga toxins
    Cell Mol Life Sci, 71 (21), 4285-300
    DOI 10.1007/s00018-014-1624-1, PubMed 24740796
  4. Bull-Hansen B, Cao Y, Berg K, Skarpen E, Rosenblum MG, Weyergang A (2014)
    Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome
    J Control Release, 182, 58-66
    DOI 10.1016/j.jconrel.2014.03.014, PubMed 24637464
  5. Cordara G, Winter HC, Goldstein IJ, Krengel U, Sandvig K (2014)
    The fungal chimerolectin MOA inhibits protein and DNA synthesis in NIH/3T3 cells and may induce BAX-mediated apoptosis
    Biochem Biophys Res Commun, 447 (4), 586-9
    DOI 10.1016/j.bbrc.2014.04.043, PubMed 24747075
  6. Danks GB, Raasholm M, Campsteijn C, Long AM, Manak JR, Lenhard B, Thompson EM (2014)
    Trans-splicing and operons in metazoans: translational control in maternally regulated development and recovery from growth arrest
    Mol Biol Evol, 32 (3), 585-99
    DOI 10.1093/molbev/msu336, PubMed 25525214
  7. Demarco RS, Eikenes ÅH, Haglund K, Jones DL (2014)
    Investigating spermatogenesis in Drosophila melanogaster
    Methods, 68 (1), 218-27
    DOI 10.1016/j.ymeth.2014.04.020, PubMed 24798812
  8. Fossum-Raunehaug S, Helgesen E, Stokke C, Skarstad K (2014)
    Escherichia coli SeqA structures relocalize abruptly upon termination of origin sequestration during multifork DNA replication
    PLoS One, 9 (10), e110575
    DOI 10.1371/journal.pone.0110575, PubMed 25333813
  9. Haugsten EM, Brech A, Liestøl K, Norman JC, Wesche J (2014)
    Photoactivation approaches reveal a role for Rab11 in FGFR4 recycling and signalling
    Traffic, 15 (6), 665-83
    DOI 10.1111/tra.12168, PubMed 24589086
  10. Hermansson E, Schultz S, Crowther D, Linse S, Winblad B, Westermark G, Johansson J, Presto J (2014)
    The chaperone domain BRICHOS prevents CNS toxicity of amyloid-β peptide in Drosophila melanogaster
    Dis Model Mech, 7 (6), 659-65
    DOI 10.1242/dmm.014787, PubMed 24682783
  11. Holland P, Torgersen ML, Sandvig K, Simonsen A (2014)
    LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis
    Traffic, 15 (12), 1390-405
    DOI 10.1111/tra.12227, PubMed 25216107
  12. Kvalvaag AS, Pust S, Sandvig K (2014)
    Vps11, a subunit of the tethering complexes HOPS and CORVET, is involved in regulation of glycolipid degradation and retrograde toxin transport
    Commun Integr Biol, 7 (1), e28129
    DOI 10.4161/cib.28129, PubMed 24778763
  13. Lund K, Bostad M, Skarpen E, Braunagel M, Kiprijanov S, Krauss S, Duncan A, Høgset A, Selbo PK (2014)
    The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
    MAbs, 6 (4), 1038-50
    DOI 10.4161/mabs.28207, PubMed 24525727
  14. Morigen M, Flåtten I, Skarstad K (2014)
    The Escherichia coli datA site promotes proper regulation of cell division
    Microbiology (Reading), 160 (Pt 4), 703-710
    DOI 10.1099/mic.0.074898-0, PubMed 24574433
  15. Odsbu I, Skarstad K (2014)
    DNA compaction in the early part of the SOS response is dependent on RecN and RecA
    Microbiology (Reading), 160 (Pt 5), 872-882
    DOI 10.1099/mic.0.075051-0, PubMed 24615185
  16. Oppelt A, Haugsten EM, Zech T, Danielsen HE, Sveen A, Lobert VH, Skotheim RI, Wesche J (2014)
    PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1
    Biochem J, 461 (3), 383-90
    DOI 10.1042/BJ20140132, PubMed 24840251
  17. Palibrk V, Lång E, Lång A, Schink KO, Rowe AD, Bøe SO (2014)
    Promyelocytic leukemia bodies tether to early endosomes during mitosis
    Cell Cycle, 13 (11), 1749-55
    DOI 10.4161/cc.28653, PubMed 24675887
  18. Phuyal S, Hessvik NP, Skotland T, Sandvig K, Llorente A (2014)
    Regulation of exosome release by glycosphingolipids and flotillins
    FEBS J, 281 (9), 2214-27
    DOI 10.1111/febs.12775, PubMed 24605801
  19. Phuyal S, Skotland T, Hessvik NP, Simolin H, Øverbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A (2014)
    The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
    J Biol Chem, 290 (7), 4225-37
    DOI 10.1074/jbc.M114.593962, PubMed 25519911
  20. Raiborg C, Stenmark H (2014)
    An ER clamp for endosome fission
    EMBO J, 34 (2), 136-7
    DOI 10.15252/embj.201490707, PubMed 25502456
  21. Reidick C, El Magraoui F, Meyer HE, Stenmark H, Platta HW (2014)
    Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO
    Cancers (Basel), 7 (1), 1-29
    DOI 10.3390/cancers7010001, PubMed 25545884
  22. Sagona AP, Nezis IP, Stenmark H (2014)
    Association of CHMP4B and autophagy with micronuclei: implications for cataract formation
    Biomed Res Int, 2014, 974393
    DOI 10.1155/2014/974393, PubMed 24741567
  23. Salvi M, Raiborg C, Hanson PI, Campsteijn C, Stenmark H, Pinna LA (2014)
    CK2 involvement in ESCRT-III complex phosphorylation
    Arch Biochem Biophys, 545, 83-91
    DOI 10.1016/j.abb.2014.01.006, PubMed 24440309
  24. Sandvig K, Bergan J, Kavaliauskiene S, Skotland T (2014)
    Lipid requirements for entry of protein toxins into cells
    Prog Lipid Res, 54, 1-13
    DOI 10.1016/j.plipres.2014.01.001, PubMed 24462587
  25. Simm R, Ahmad I, Rhen M, Le Guyon S, Römling U (2014)
    Regulation of biofilm formation in Salmonella enterica serovar Typhimurium
    Future Microbiol, 9 (11), 1261-82
    DOI 10.2217/fmb.14.88, PubMed 25437188
  26. Skotland T, Iversen TG, Sandvig K (2014)
    Development of nanoparticles for clinical use
    Nanomedicine (Lond), 9 (9), 1295-9
    DOI 10.2217/nnm.14.81, PubMed 25204821
  27. Sletten T, Kostas M, Bober J, Sorensen V, Yadollahi M, Olsnes S, Tomala J, Otlewski J, Zakrzewska M, Wiedlocha A (2014)
    Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1)
    PLoS One, 9 (3), e90687
    DOI 10.1371/journal.pone.0090687, PubMed 24595027
  28. Słomińska-Wojewódzka M, Pawlik A, Sokołowska I, Antoniewicz J, Węgrzyn G, Sandvig K (2014)
    The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol
    Biochem J, 457 (3), 485-96
    DOI 10.1042/BJ20130155, PubMed 24200403
  29. Solhaug A, Torgersen ML, Holme JA, Lagadic-Gossmann D, Eriksen GS (2014)
    Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol
    Toxicology, 326, 119-29
    DOI 10.1016/j.tox.2014.10.009, PubMed 25456271
  30. Stiebler AC, Freitag J, Schink KO, Stehlik T, Tillmann BA, Ast J, Bölker M (2014)
    Ribosomal readthrough at a short UGA stop codon context triggers dual localization of metabolic enzymes in Fungi and animals
    PLoS Genet, 10 (10), e1004685
    DOI 10.1371/journal.pgen.1004685, PubMed 25340584
  31. Thoresen SB, Campsteijn C, Vietri M, Schink KO, Liestøl K, Andersen JS, Raiborg C, Stenmark H (2014)
    ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4
    Nat Cell Biol, 16 (6), 550-60
    DOI 10.1038/ncb2959, PubMed 24814515
  32. Wegner CS, Schink KO, Stenmark H, Brech A (2014)
    Monitoring phosphatidylinositol 3-phosphate in multivesicular endosome biogenesis
    Methods Enzymol, 534, 3-23
    DOI 10.1016/B978-0-12-397926-1.00001-9, PubMed 24359945
  33. Yermakova A, Klokk TI, Cole R, Sandvig K, Mantis NJ (2014)
    Antibody-mediated inhibition of ricin toxin retrograde transport
    mBio, 5 (2), e00995
    DOI 10.1128/mBio.00995-13, PubMed 24713323

Publications 2013

  1. Amoasii L, Hnia K, Chicanne G, Brech A, Cowling BS, Müller MM, Schwab Y, Koebel P, Ferry A, Payrastre B, Laporte J (2013)
    Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo
    J Cell Sci, 126 (Pt 8), 1806-19
    DOI 10.1242/jcs.118505, PubMed 23444364
  2. Bergan J, Skotland T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2013)
    The ether lipid precursor hexadecylglycerol causes major changes in the lipidome of HEp-2 cells
    PLoS One, 8 (9), e75904
    DOI 10.1371/journal.pone.0075904, PubMed 24098742
  3. Bostad M, Berg K, Høgset A, Skarpen E, Stenmark H, Selbo PK (2013)
    Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
    J Control Release, 168 (3), 317-26
    DOI 10.1016/j.jconrel.2013.03.023, PubMed 23567040
  4. Eikenes ÅH, Brech A, Stenmark H, Haglund K (2013)
    Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline
    Dev Biol, 377 (1), 9-20
    DOI 10.1016/j.ydbio.2013.02.021, PubMed 23499247
  5. Engedal N, Torgersen ML, Guldvik IJ, Barfeld SJ, Bakula D, Sætre F, Hagen LK, Patterson JB, Proikas-Cezanne T, Seglen PO, Simonsen A, Mills IG (2013)
    Modulation of intracellular calcium homeostasis blocks autophagosome formation
    Autophagy, 9 (10), 1475-90
    DOI 10.4161/auto.25900, PubMed 23970164
  6. Flinder LI, Wierød L, Rosseland CM, Huitfeldt HS, Skarpen E (2013)
    FAK regulates Cdk2 in EGF-stimulated primary cultures of hepatocytes
    J Cell Physiol, 228 (6), 1304-13
    DOI 10.1002/jcp.24287, PubMed 23168795
  7. Flåtten I, Skarstad K (2013)
    The Fis protein has a stimulating role in initiation of replication in Escherichia coli in vivo
    PLoS One, 8 (12), e83562
    DOI 10.1371/journal.pone.0083562, PubMed 24358293
  8. Grallert B, Boye E (2013)
    GCN2, an old dog with new tricks
    Biochem Soc Trans, 41 (6), 1687-91
    DOI 10.1042/BST20130210, PubMed 24256275
  9. Gregers TF, Skånland SS, Wälchli S, Bakke O, Sandvig K (2013)
    BiP negatively affects ricin transport
    Toxins (Basel), 5 (5), 969-82
    DOI 10.3390/toxins5050969, PubMed 23666197
  10. Haugsten EM, Oppelt A, Wesche J (2013)
    Phosphatidylinositol 5-phosphate is a second messenger important for cell migration
    Commun Integr Biol, 6 (5), e25446
    DOI 10.4161/cib.25446, PubMed 24265857
  11. Henne WM, Stenmark H, Emr SD (2013)
    Molecular mechanisms of the membrane sculpting ESCRT pathway
    Cold Spring Harb Perspect Biol, 5 (9)
    DOI 10.1101/cshperspect.a016766, PubMed 24003212
  12. Hessvik NP, Sandvig K, Llorente A (2013)
    Exosomal miRNAs as Biomarkers for Prostate Cancer
    Front Genet, 4, 36
    DOI 10.3389/fgene.2013.00036, PubMed 23519132
  13. Isakson P, Lystad AH, Breen K, Koster G, Stenmark H, Simonsen A (2013)
    TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
    Autophagy, 9 (12), 1955-64
    DOI 10.4161/auto.26085, PubMed 24128730
  14. Kavaliauskiene S, Nymark CM, Bergan J, Simm R, Sylvänne T, Simolin H, Ekroos K, Skotland T, Sandvig K (2013)
    Cell density-induced changes in lipid composition and intracellular trafficking
    Cell Mol Life Sci, 71 (6), 1097-116
    DOI 10.1007/s00018-013-1441-y, PubMed 23921715
  15. Knævelsrud H, Søreng K, Raiborg C, Håberg K, Rasmuson F, Brech A, Liestøl K, Rusten TE, Stenmark H, Neufeld TP, Carlsson SR, Simonsen A (2013)
    Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation
    J Cell Biol, 202 (2), 331-49
    DOI 10.1083/jcb.201205129, PubMed 23878278
  16. Kvalvaag AS, Pust S, Sundet KI, Engedal N, Simm R, Sandvig K (2013)
    The ERM proteins ezrin and moesin regulate retrograde Shiga toxin transport
    Traffic, 14 (7), 839-52
    DOI 10.1111/tra.12077, PubMed 23593995
  17. Llorente A, Skotland T, Sylvänne T, Kauhanen D, Róg T, Orłowski A, Vattulainen I, Ekroos K, Sandvig K (2013)
    Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
    Biochim Biophys Acta, 1831 (7), 1302-9
    DOI 10.1016/j.bbalip.2013.04.011, PubMed 24046871
  18. Lueke K, Kaiser T, Svetlitchny A, Welzel O, Wenzel EM, Tyagarajan S, Kornhuber J, Groemer TW (2013)
    Basic presynaptic functions in hippocampal neurons are not affected by acute or chronic lithium treatment
    J Neural Transm (Vienna), 121 (2), 211-9
    DOI 10.1007/s00702-013-1087-9, PubMed 24036894
  19. Nadratowska-Wesolowska B, Haugsten EM, Zakrzewska M, Jakimowicz P, Zhen Y, Pajdzik D, Wesche J, Wiedlocha A (2013)
    RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789
    Oncogene, 33 (40), 4823-36
    DOI 10.1038/onc.2013.425, PubMed 24141780
  20. O Farrell F, Rusten TE, Stenmark H (2013)
    Phosphoinositide 3-kinases as accelerators and brakes of autophagy
    FEBS J, 280 (24), 6322-37
    DOI 10.1111/febs.12486, PubMed 23953235
  21. O'Farrell F, Wang S, Katheder N, Rusten TE, Samakovlis C (2013)
    Two-tiered control of epithelial growth and autophagy by the insulin receptor and the ret-like receptor, stitcher
    PLoS Biol, 11 (7), e1001612
    DOI 10.1371/journal.pbio.1001612, PubMed 23935447
  22. Raiborg C, Schink KO, Stenmark H (2013)
    Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic
    FEBS J, 280 (12), 2730-42
    DOI 10.1111/febs.12116, PubMed 23289851
  23. Rødland GE, Tvegård T, Boye E, Grallert B (2013)
    Crosstalk between the Tor and Gcn2 pathways in response to different stresses
    Cell Cycle, 13 (3), 453-61
    DOI 10.4161/cc.27270, PubMed 24280780
  24. Sandvig K, Skotland T, van Deurs B, Klokk TI (2013)
    Retrograde transport of protein toxins through the Golgi apparatus
    Histochem Cell Biol, 140 (3), 317-26
    DOI 10.1007/s00418-013-1111-z, PubMed 23765164
  25. Schink KO, Raiborg C, Stenmark H (2013)
    Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling
    Bioessays, 35 (10), 900-12
    DOI 10.1002/bies.201300064, PubMed 23881848
  26. Schneikert J, Vijaya Chandra SH, Ruppert JG, Ray S, Wenzel EM, Behrens J (2013)
    Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation
    PLoS One, 8 (7), e68072
    DOI 10.1371/journal.pone.0068072, PubMed 23840886
  27. Shahzidi S, Brech A, Sioud M, Li X, Suo Z, Nesland JM, Peng Q (2013)
    Lamin A/C cleavage by caspase-6 activation is crucial for apoptotic induction by photodynamic therapy with hexaminolevulinate in human B-cell lymphoma cells
    Cancer Lett, 339 (1), 25-32
    DOI 10.1016/j.canlet.2013.07.026, PubMed 23916608
  28. Skarstad K, Katayama T (2013)
    Regulating DNA replication in bacteria
    Cold Spring Harb Perspect Biol, 5 (4), a012922
    DOI 10.1101/cshperspect.a012922, PubMed 23471435
  29. Slominska-Wojewodzka M, Sandvig K (2013)
    Ricin and Ricin-Containing Immunotoxins: Insights into Intracellular Transport and Mechanism of action in Vitro
    Antibodies, 2 (2), 236-269
    DOI 10.3390/antib2020236
  30. Solhaug A, Holme JA, Haglund K, Dendele B, Sergent O, Pestka J, Lagadic-Gossmann D, Eriksen GS (2013)
    Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages
    Toxicol Lett, 219 (1), 8-17
    DOI 10.1016/j.toxlet.2013.02.012, PubMed 23454835
  31. Stratford EW, Bostad M, Castro R, Skarpen E, Berg K, Høgset A, Myklebost O, Selbo PK (2013)
    Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity
    Biochim Biophys Acta, 1830 (8), 4235-43
    DOI 10.1016/j.bbagen.2013.04.033, PubMed 23643966
  32. Vörös A, Simm R, Kroeger JK, Kolstø AB (2013)
    Gene transcription from the linear plasmid pBClin15 leads to cell lysis and extracellular DNA-dependent aggregation of Bacillus cereus ATCC 14579 in response to quinolone-induced stress
    Microbiology (Reading), 159 (Pt 11), 2283-2293
    DOI 10.1099/mic.0.069674-0, PubMed 24002748
  33. Weel-Sneve R, Kristiansen KI, Odsbu I, Dalhus B, Booth J, Rognes T, Skarstad K, Bjørås M (2013)
    Single transmembrane peptide DinQ modulates membrane-dependent activities
    PLoS Genet, 9 (2), e1003260
    DOI 10.1371/journal.pgen.1003260, PubMed 23408903
  34. Wu X, Chen JY, Brech A, Fang C, Wang J, Helm PJ, Peng Q (2013)
    The use of femto-second lasers to trigger powerful explosions of gold nanorods to destroy cancer cells
    Biomaterials, 34 (26), 6157-62
    DOI 10.1016/j.biomaterials.2013.04.048, PubMed 23706782
  35. Zakrzewska M, Haugsten EM, Nadratowska-Wesolowska B, Oppelt A, Hausott B, Jin Y, Otlewski J, Wesche J, Wiedlocha A (2013)
    ERK-mediated phosphorylation of fibroblast growth factor receptor 1 on Ser777 inhibits signaling
    Sci Signal, 6 (262), ra11
    DOI 10.1126/scisignal.2003087, PubMed 23405013

Publications 2012

  1. Abrahamsen H, Stenmark H, Platta HW (2012)
    Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression
    FEBS Lett, 586 (11), 1584-91
    DOI 10.1016/j.febslet.2012.04.046, PubMed 22673570
  2. Becker GL, Lu Y, Hardes K, Strehlow B, Levesque C, Lindberg I, Sandvig K, Bakowsky U, Day R, Garten W, Steinmetzer T (2012)
    Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases
    J Biol Chem, 287 (26), 21992-2003
    DOI 10.1074/jbc.M111.332643, PubMed 22539349
  3. Bergan J, Dyve Lingelem AB, Simm R, Skotland T, Sandvig K (2012)
    Shiga toxins
    Toxicon, 60 (6), 1085-107
    DOI 10.1016/j.toxicon.2012.07.016, PubMed 22960449
  4. Bøe CA, Knutsen JH, Boye E, Grallert B (2012)
    Hpz1 modulates the G1-S transition in fission yeast
    PLoS One, 7 (9), e44539
    DOI 10.1371/journal.pone.0044539, PubMed 22970243
  5. Bøe CA, Krohn M, Rødland GE, Capiaghi C, Maillard O, Thoma F, Boye E, Grallert B (2012)
    Induction of a G1-S checkpoint in fission yeast
    Proc Natl Acad Sci U S A, 109 (25), 9911-6
    DOI 10.1073/pnas.1204901109, PubMed 22665798
  6. Danks G, Campsteijn C, Parida M, Butcher S, Doddapaneni H, Fu B, Petrin R, Metpally R, Lenhard B, Wincker P, Chourrout D, Thompson EM, Manak JR (2012)
    OikoBase: a genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica
    Nucleic Acids Res, 41 (Database issue), D845-53
    DOI 10.1093/nar/gks1159, PubMed 23185044
  7. Fingland N, Flåtten I, Downey CD, Fossum-Raunehaug S, Skarstad K, Crooke E (2012)
    Depletion of acidic phospholipids influences chromosomal replication in Escherichia coli
    Microbiologyopen, 1 (4), 450-66
    DOI 10.1002/mbo3.46, PubMed 23233230
  8. Haglund K, Dikic I (2012)
    The role of ubiquitylation in receptor endocytosis and endosomal sorting
    J Cell Sci, 125 (Pt 2), 265-75
    DOI 10.1242/jcs.091280, PubMed 22357968
  9. Hessvik NP, Phuyal S, Brech A, Sandvig K, Llorente A (2012)
    Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells
    Biochim Biophys Acta, 1819 (11-12), 1154-63
    DOI 10.1016/j.bbagrm.2012.08.016, PubMed 22982408
  10. Huotari J, Meyer-Schaller N, Hubner M, Stauffer S, Katheder N, Horvath P, Mancini R, Helenius A, Peter M (2012)
    Cullin-3 regulates late endosome maturation
    Proc Natl Acad Sci U S A, 109 (3), 823-8
    DOI 10.1073/pnas.1118744109, PubMed 22219362
  11. Ilina P, Hyvonen Z, Saura M, Sandvig K, Yliperttula M, Ruponen M (2012)
    Genetic blockage of endocytic pathways reveals differences in the intracellular processing of non-viral gene delivery systems
    J Control Release, 163 (3), 385-95
    DOI 10.1016/j.jconrel.2012.09.016, PubMed 23041276
  12. Iversen TG, Frerker N, Sandvig K (2012)
    Uptake of ricinB-quantum dot nanoparticles by a macropinocytosis-like mechanism
    J Nanobiotechnology, 10, 33
    DOI 10.1186/1477-3155-10-33, PubMed 22849338
  13. Jha AN, Singh VK, Kumari N, Singh A, Antony J, van Tong H, Singh S, Pati SS, Patra PK, Singh R, Toan NL, Song le H, Assaf A, Messias-Reason IJ, Velavan TP, Singh L, Thangaraj K (2012)
    IL-4 haplotype -590T, -34T and intron-3 VNTR R2 is associated with reduced malaria risk among ancestral indian tribal populations
    PLoS One, 7 (10), e48136
    DOI 10.1371/journal.pone.0048136, PubMed 23110190
  14. Kalra H, Simpson RJ, Ji H, Aikawa E, Altevogt P, Askenase P, Bond VC, Borràs FE, Breakefield X, Budnik V, Buzas E, Camussi G, Clayton A, Cocucci E, Falcon-Perez JM, Gabrielsson S, Gho YS, Gupta D, Harsha HC, Hendrix A, Hill AF, Inal JM, Jenster G, Krämer-Albers EM, Lim SK et al. (2012)
    Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
    PLoS Biol, 10 (12), e1001450
    DOI 10.1371/journal.pbio.1001450, PubMed 23271954
  15. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A et al. (2012)
    Guidelines for the use and interpretation of assays for monitoring autophagy
    Autophagy, 8 (4), 445-544
    DOI 10.4161/auto.19496, PubMed 22966490
  16. Lobert VH, Bruun J, Abrahamsen H, Lothe RA, Stenmark H, Kolberg M, Campsteijn C (2012)
    Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin
    EMBO Rep, 14 (1), 10-1
    DOI 10.1038/embor.2012.188, PubMed 23229585
  17. Lobert VH, Stenmark H (2012)
    The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain
    J Cell Sci, 125 (Pt 1), 29-36
    DOI 10.1242/jcs.088310, PubMed 22266905
  18. Nezis IP (2012)
    Selective autophagy in Drosophila
    Int J Cell Biol, 2012, 146767
    DOI 10.1155/2012/146767, PubMed 22567011
  19. Nezis IP, Stenmark H (2012)
    p62 at the interface of autophagy, oxidative stress signaling, and cancer
    Antioxid Redox Signal, 17 (5), 786-93
    DOI 10.1089/ars.2011.4394, PubMed 22074114
  20. Oksvold MP, Pedersen NM, Forfang L, Smeland EB (2012)
    Effect of cycloheximide on epidermal growth factor receptor trafficking and signaling
    FEBS Lett, 586 (20), 3575-81
    DOI 10.1016/j.febslet.2012.08.022, PubMed 22971756
  21. Oppelt A, Lobert VH, Haglund K, Mackey AM, Rameh LE, Liestøl K, Schink KO, Pedersen NM, Wenzel EM, Haugsten EM, Brech A, Rusten TE, Stenmark H, Wesche J (2012)
    Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration
    EMBO Rep, 14 (1), 57-64
    DOI 10.1038/embor.2012.183, PubMed 23154468
  22. Pedersen NM, Raiborg C, Brech A, Skarpen E, Roxrud I, Platta HW, Liestøl K, Stenmark H (2012)
    The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion
    Traffic, 13 (11), 1547-63
    DOI 10.1111/j.1600-0854.2012.01400.x, PubMed 22816767
  23. Platta HW, Abrahamsen H, Thoresen SB, Stenmark H (2012)
    Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1
    Biochem J, 441 (1), 399-406
    DOI 10.1042/BJ20111424, PubMed 21936852
  24. Pust S, Klokk TI, Musa N, Jenstad M, Risberg B, Erikstein B, Tcatchoff L, Liestøl K, Danielsen HE, van Deurs B, Sandvig K (2012)
    Flotillins as regulators of ErbB2 levels in breast cancer
    Oncogene, 32 (29), 3443-51
    DOI 10.1038/onc.2012.357, PubMed 22869152
  25. Sak MM, Breen K, Rønning SB, Pedersen NM, Bertelsen V, Stang E, Madshus IH (2012)
    The oncoprotein ErbB3 is endocytosed in the absence of added ligand in a clathrin-dependent manner
    Carcinogenesis, 33 (5), 1031-9
    DOI 10.1093/carcin/bgs128, PubMed 22436610
  26. Sandvig K, Llorente A (2012)
    Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3
    Mol Cell Proteomics, 11 (7), M111.012914
    DOI 10.1074/mcp.M111.012914, PubMed 22457534
  27. Skotland T (2012)
    Molecular imaging: challenges of bringing imaging of intracellular targets into common clinical use
    Contrast Media Mol Imaging, 7 (1), 1-6
    DOI 10.1002/cmmi.458, PubMed 22344874
  28. Stenmark H (2012)
    The Rabs: a family at the root of metazoan evolution
    BMC Biol, 10, 68
    DOI 10.1186/1741-7007-10-68, PubMed 22873178
  29. Stokke C, Flåtten I, Skarstad K (2012)
    An easy-to-use simulation program demonstrates variations in bacterial cell cycle parameters depending on medium and temperature
    PLoS One, 7 (2), e30981
    DOI 10.1371/journal.pone.0030981, PubMed 22348034
  30. Stratford EW, Castro R, Daffinrud J, Skårn M, Lauvrak S, Munthe E, Myklebost O (2012)
    Characterization of liposarcoma cell lines for preclinical and biological studies
    Sarcoma, 2012, 148614
    DOI 10.1155/2012/148614, PubMed 22911243
  31. Szlachcic A, Pala K, Zakrzewska M, Jakimowicz P, Wiedlocha A, Otlewski J (2012)
    FGF1-gold nanoparticle conjugates targeting FGFR efficiently decrease cell viability upon NIR irradiation
    Int J Nanomedicine, 7, 5915-27
    DOI 10.2147/IJN.S36575, PubMed 23226697
  32. Tabassum R, Chauhan G, Dwivedi OP, Mahajan A, Jaiswal A, Kaur I, Bandesh K, Singh T, Mathai BJ, Pandey Y, Chidambaram M, Sharma A, Chavali S, Sengupta S, Ramakrishnan L, Venkatesh P, Aggarwal SK, Ghosh S, Prabhakaran D, Srinath RK, Saxena M, Banerjee M, Mathur S, Bhansali A, Shah VN et al. (2012)
    Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21
    Diabetes, 62 (3), 977-86
    DOI 10.2337/db12-0406, PubMed 23209189
  33. Tcatchoff L, Andersson S, Utskarpen A, Klokk TI, Skånland SS, Pust S, Gerke V, Sandvig K (2012)
    Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin
    PLoS One, 7 (7), e40429
    DOI 10.1371/journal.pone.0040429, PubMed 22792315
  34. Waldminghaus T, Weigel C, Skarstad K (2012)
    Replication fork movement and methylation govern SeqA binding to the Escherichia coli chromosome
    Nucleic Acids Res, 40 (12), 5465-76
    DOI 10.1093/nar/gks187, PubMed 22373925
  35. Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S (2012)
    A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice
    Cancer Res, 72 (11), 2822-32
    DOI 10.1158/0008-5472.CAN-11-3336, PubMed 22440753
  36. Zhen Y, Sørensen V, Skjerpen CS, Haugsten EM, Jin Y, Wälchli S, Olsnes S, Wiedlocha A (2012)
    Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnα1 and Kpnβ1
    Traffic, 13 (5), 650-64
    DOI 10.1111/j.1600-0854.2012.01341.x, PubMed 22321063
  37. Østerud B, Skotland T (2012)
    Doping analyses are not on safe ground
    Tidsskr Nor Laegeforen, 132 (8), 929-30
    DOI 10.4045/tidsskr.12.0252, PubMed 22562317

Publications 2011

  1. Abrahamsen H, Stenmark H (2011)
    Cell biology. Growth signaling from inside
    Science, 334 (6056), 611-2
    DOI 10.1126/science.1214355, PubMed 22053037
  2. Bartlett BJ, Isakson P, Lewerenz J, Sanchez H, Kotzebue RW, Cumming RC, Harris GL, Nezis IP, Schubert DR, Simonsen A, Finley KD (2011)
    p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects
    Autophagy, 7 (6), 572-83
    DOI 10.4161/auto.7.6.14943, PubMed 21325881
  3. Cordara G, Egge-Jacobsen W, Johansen HT, Winter HC, Goldstein IJ, Sandvig K, Krengel U (2011)
    Marasmius oreades agglutinin (MOA) is a chimerolectin with proteolytic activity
    Biochem Biophys Res Commun, 408 (3), 405-10
    DOI 10.1016/j.bbrc.2011.04.031, PubMed 21513701
  4. Dang H, Klokk TI, Schaheen B, McLaughlin BM, Thomas AJ, Durns TA, Bitler BG, Sandvig K, Fares H (2011)
    Derlin-dependent retrograde transport from endosomes to the Golgi apparatus
    Traffic, 12 (10), 1417-31
    DOI 10.1111/j.1600-0854.2011.01243.x, PubMed 21722281
  5. Dyve Lingelem AB, Bergan J, Sandvig K (2011)
    Inhibitors of intravesicular acidification protect against Shiga toxin in a pH-independent manner
    Traffic, 13 (3), 443-54
    DOI 10.1111/j.1600-0854.2011.01319.x, PubMed 22132807
  6. Engedal N, Skotland T, Torgersen ML, Sandvig K (2011)
    Shiga toxin and its use in targeted cancer therapy and imaging
    Microb Biotechnol, 4 (1), 32-46
    DOI 10.1111/j.1751-7915.2010.00180.x, PubMed 21255370
  7. Eskelinen EL, Reggiori F, Baba M, Kovács AL, Seglen PO (2011)
    Seeing is believing: the impact of electron microscopy on autophagy research
    Autophagy, 7 (9), 935-56
    DOI 10.4161/auto.7.9.15760, PubMed 21566462
  8. Freitag J, Lanver D, Böhmer C, Schink KO, Bölker M, Sandrock B (2011)
    Septation of infectious hyphae is critical for appressoria formation and virulence in the smut fungus Ustilago maydis
    PLoS Pathog, 7 (5), e1002044
    DOI 10.1371/journal.ppat.1002044, PubMed 21625538
  9. George A, Panda S, Kudmulwar D, Chhatbar SP, Nayak SC, Krishnan HH (2011)
    Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation
    J Biol Chem, 287 (7), 5042-58
    DOI 10.1074/jbc.M111.308916, PubMed 22184107
  10. Grimm I, Saffian D, Platta HW, Erdmann R (2011)
    The AAA-type ATPases Pex1p and Pex6p and their role in peroxisomal matrix protein import in Saccharomyces cerevisiae
    Biochim Biophys Acta, 1823 (1), 150-8
    DOI 10.1016/j.bbamcr.2011.09.005, PubMed 21963882
  11. Grunau S, Lay D, Mindthoff S, Platta HW, Girzalsky W, Just WW, Erdmann R (2011)
    The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae
    Biochem J, 434 (1), 161-70
    DOI 10.1042/BJ20101115, PubMed 21121900
  12. Haglund K, Nezis IP, Stenmark H (2011)
    Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
    Commun Integr Biol, 4 (1), 1-9
    DOI 10.4161/cib.4.1.13550, PubMed 21509167
  13. Haugsten EM, Zakrzewska M, Brech A, Pust S, Olsnes S, Sandvig K, Wesche J (2011)
    Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling
    PLoS One, 6 (7), e21708
    DOI 10.1371/journal.pone.0021708, PubMed 21779335
  14. Hausott B, Vallant N, Hochfilzer M, Mangger S, Irschick R, Haugsten EM, Klimaschewski L (2011)
    Leupeptin enhances cell surface localization of fibroblast growth factor receptor 1 in adult sensory neurons by increased recycling
    Eur J Cell Biol, 91 (2), 129-38
    DOI 10.1016/j.ejcb.2011.09.009, PubMed 22169219
  15. Helmrich U, Marsano A, Melly L, Wolff T, Christ L, Heberer M, Scherberich A, Martin I, Banfi A (2011)
    Generation of human adult mesenchymal stromal/stem cells expressing defined xenogenic vascular endothelial growth factor levels by optimized transduction and flow cytometry purification
    Tissue Eng Part C Methods, 18 (4), 283-92
    DOI 10.1089/ten.TEC.2011.0413, PubMed 22070632
  16. Hurley JH, Stenmark H (2011)
    Molecular mechanisms of ubiquitin-dependent membrane traffic
    Annu Rev Biophys, 40, 119-42
    DOI 10.1146/annurev-biophys-042910-155404, PubMed 21332354
  17. Iversen TG (2011)
    Nanoparticles hinder intracellular transport
    Trac-Trends Anal. Chem., 30 (10), VII-VIII
  18. Iversen TG, Skotland T, Sandvig K (2011)
    Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies
    Nano Today, 6 (2), 176-185
    DOI 10.1016/j.nantod.2011.02.003
  19. Jin Y, Zhen Y, Haugsten EM, Wiedlocha A (2011)
    The driver of malignancy in KG-1a leukemic cells, FGFR1OP2-FGFR1, encodes an HSP90 addicted oncoprotein
    Cell Signal, 23 (11), 1758-66
    DOI 10.1016/j.cellsig.2011.06.010, PubMed 21745565
  20. Johnsen E, Wilson SR, Odsbu I, Krapp A, Malerod H, Skarstad K, Lundanes E (2011)
    Hydrophilic interaction chromatography of nucleoside triphosphates with temperature as a separation parameter
    J Chromatogr A, 1218 (35), 5981-6
    DOI 10.1016/j.chroma.2011.01.066, PubMed 21315360
  21. Klokk TI, Lingelem AB, Myrann AG, Sandvig K (2011)
    Role of phospholipase A(2) in retrograde transport of ricin
    Toxins (Basel), 3 (9), 1203-19
    DOI 10.3390/toxins3091203, PubMed 22069763
  22. Knutsen JH, Rein ID, Rothe C, Stokke T, Grallert B, Boye E (2011)
    Cell-cycle analysis of fission yeast cells by flow cytometry
    PLoS One, 6 (2), e17175
    DOI 10.1371/journal.pone.0017175, PubMed 21386895
  23. Lind GE, Raiborg C, Danielsen SA, Rognum TO, Thiis-Evensen E, Hoff G, Nesbakken A, Stenmark H, Lothe RA (2011)
    SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
    Oncogene, 30 (37), 3967-78
    DOI 10.1038/onc.2011.109, PubMed 21499309
  24. Lobert VH, Stenmark H (2011)
    Cell polarity and migration: emerging role for the endosomal sorting machinery
    Physiology (Bethesda), 26 (3), 171-80
    DOI 10.1152/physiol.00054.2010, PubMed 21670163
  25. Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
    Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
    Traffic, 12 (9), 1211-26
    DOI 10.1111/j.1600-0854.2011.01220.x, PubMed 21564451
  26. Martinez AL, Roxrud I (2011)
    Basic and discovery-based translational research on cancer was on the agenda at the 21st Congress of the European Association for Cancer Research (EACR) in Oslo, Norway, 26-29 June 2010
    Clin. Transl. Oncol., 13 (1), 1-2
    DOI 10.1007/s12094-011-0608-y
  27. Moosmann A, Campsteijn C, Jansen PW, Nasrallah C, Raasholm M, Stunnenberg HG, Thompson EM (2011)
    Histone variant innovation in a rapidly evolving chordate lineage
    BMC Evol Biol, 11, 208
    DOI 10.1186/1471-2148-11-208, PubMed 21756361
  28. Platta HW, Stenmark H (2011)
    Endocytosis and signaling
    Curr Opin Cell Biol, 23 (4), 393-403
    DOI 10.1016/j.ceb.2011.03.008, PubMed 21474295
  29. Raiborg C, Stenmark H (2011)
    Cell biology. A helix for the final cut
    Science, 331 (6024), 1533-4
    DOI 10.1126/science.1204208, PubMed 21436431
  30. Rusten TE, Vaccari T, Stenmark H (2011)
    Shaping development with ESCRTs
    Nat Cell Biol, 14 (1), 38-45
    DOI 10.1038/ncb2381, PubMed 22193162
  31. Rønning SB, Pedersen NM, Madshus IH, Stang E (2011)
    CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor
    Exp Cell Res, 317 (13), 1804-16
    DOI 10.1016/j.yexcr.2011.05.016, PubMed 21635887
  32. Sagona AP, Nezis IP, Bache KG, Haglund K, Bakken AC, Skotheim RI, Stenmark H (2011)
    A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
    PLoS One, 6 (3), e17086
    DOI 10.1371/journal.pone.0017086, PubMed 21455500
  33. Sandvig K, Pust S, Skotland T, van Deurs B (2011)
    Clathrin-independent endocytosis: mechanisms and function
    Curr Opin Cell Biol, 23 (4), 413-20
    DOI 10.1016/j.ceb.2011.03.007, PubMed 21466956
  34. Schink KO, Stenmark H (2011)
    Cell differentiation: midbody remnants - junk or fate factors?
    Curr Biol, 21 (23), R958-60
    DOI 10.1016/j.cub.2011.10.035, PubMed 22153165
  35. Shahzidi S, Cunderlíková B, Więdłocha A, Zhen Y, Vasovič V, Nesland JM, Peng Q (2011)
    Simultaneously targeting mitochondria and endoplasmic reticulum by photodynamic therapy induces apoptosis in human lymphoma cells
    Photochem Photobiol Sci, 10 (11), 1773-82
    DOI 10.1039/c1pp05169e, PubMed 21881674
  36. Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E (2011)
    Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
    Int J Cancer, 131 (3), 570-81
    DOI 10.1002/ijc.26392, PubMed 21866551
  37. Skotland T, Iversen TG, Sandvig K (2011)
    Comment on "short ligands affect modes of QD uptake and elimination in human cells"
    ACS Nano, 5 (10), 7690; author reply 7691-2
    DOI 10.1021/nn2021953, PubMed 22023400
  38. Sokołowska I, Wälchli S, Węgrzyn G, Sandvig K, Słomińska-Wojewódzka M (2011)
    A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation
    Biochem J, 436 (2), 371-85
    DOI 10.1042/BJ20101493, PubMed 21388347
  39. Stenmark H (2011)
    Harald Stenmark: hands on FYVE-fingers. Interview by Caitlin Sedwick
    J Cell Biol, 192 (4), 544-5
    DOI 10.1083/jcb.1924pi, PubMed 21339328
  40. Stratford EW, Castro R, Wennerstrom A, Holm R, Munthe E, Lauvrak S, Bjerkehagen B, Myklebost O (2011)
    Liposarcoma Cells with Aldefluor and CD133 Activity have a Cancer Stem Cell Potential
    Clin Sarcoma Res, 1 (1), 8
    DOI 10.1186/2045-3329-1-8, PubMed 22612877
  41. Takahashi Y, Shimokawa N, Esmaeili-Mahani S, Morita A, Masuda H, Iwasaki T, Tamura J, Haglund K, Koibuchi N (2011)
    Ligand-induced downregulation of TrkA is partly regulated through ubiquitination by Cbl
    FEBS Lett, 585 (12), 1741-7
    DOI 10.1016/j.febslet.2011.04.056, PubMed 21570973
  42. Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2011)
    Protein C mutation (A267T) results in ER retention and unfolded protein response activation
    PLoS One, 6 (8), e24009
    DOI 10.1371/journal.pone.0024009, PubMed 21901152
  43. Ugland H, Naderi S, Brech A, Collas P, Blomhoff HK (2011)
    cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1
    Autophagy, 7 (10), 1199-211
    DOI 10.4161/auto.7.10.16649, PubMed 21750416
  44. Warsame AA, Aasheim HC, Nustad K, Trøen G, Tierens A, Wang V, Randen U, Dong HP, Heim S, Brech A, Delabie J (2011)
    Splenic marginal zone lymphoma with VH1-02 gene rearrangement expresses poly- and self-reactive antibodies with similar reactivity
    Blood, 118 (12), 3331-9
    DOI 10.1182/blood-2011-03-341651, PubMed 21725051
  45. Wegner CS, Rodahl LM, Stenmark H (2011)
    ESCRT proteins and cell signalling
    Traffic, 12 (10), 1291-7
    DOI 10.1111/j.1600-0854.2011.01210.x, PubMed 21518165
  46. Wesche J, Haglund K, Haugsten EM (2011)
    Fibroblast growth factors and their receptors in cancer
    Biochem J, 437 (2), 199-213
    DOI 10.1042/BJ20101603, PubMed 21711248
  47. Zakrzewska M, Sørensen V, Jin Y, Wiedlocha A, Olsnes S (2011)
    Translocation of exogenous FGF1 into cytosol and nucleus is a periodic event independent of receptor kinase activity
    Exp Cell Res, 317 (7), 1005-15
    DOI 10.1016/j.yexcr.2011.01.003, PubMed 21223966
  48. Øverbye A, Sætre F, Hagen LK, Johansen HT, Seglen PO (2011)
    Autophagic activity measured in whole rat hepatocytes as the accumulation of a novel BHMT fragment (p10), generated in amphisomes by the asparaginyl proteinase, legumain
    Autophagy, 7 (9), 1011-27
    DOI 10.4161/auto.7.9.16436, PubMed 21610319

Publications 2010

  1. Abrahamsen H, Stenmark H (2010)
    Protein secretion: unconventional exit by exophagy
    Curr Biol, 20 (9), R415-8
    DOI 10.1016/j.cub.2010.03.011, PubMed 20462486
  2. Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T (2010)
    p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
    Autophagy, 6 (3), 330-44
    DOI 10.4161/auto.6.3.11226, PubMed 20168092
  3. Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A (2010)
    The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
    Mol Cell, 38 (2), 265-79
    DOI 10.1016/j.molcel.2010.04.007, PubMed 20417604
  4. Groves B, Abrahamsen H, Clingan H, Frantz M, Mavor L, Bailey J, Ma D (2010)
    An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy
    PLoS One, 5 (1), e8877
    DOI 10.1371/journal.pone.0008877, PubMed 20126274
  5. Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestøl K, Dikic I, Palmer R, Stenmark H (2010)
    Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
    Curr Biol, 20 (10), 944-50
    DOI 10.1016/j.cub.2010.03.068, PubMed 20451383
  6. Halaas O, Steigedal M, Haug M, Awuh JA, Ryan L, Brech A, Sato S, Husebye H, Cangelosi GA, Akira S, Strong RK, Espevik T, Flo TH (2010)
    Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathway
    J Infect Dis, 201 (5), 783-92
    DOI 10.1086/650493, PubMed 20121435
  7. Haugsten EM, Wiedlocha A, Olsnes S, Wesche J (2010)
    Roles of fibroblast growth factor receptors in carcinogenesis
    Mol Cancer Res, 8 (11), 1439-52
    DOI 10.1158/1541-7786.MCR-10-0168, PubMed 21047773
  8. Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, Nilsen NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T (2010)
    The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
    Immunity, 33 (4), 583-96
    DOI 10.1016/j.immuni.2010.09.010, PubMed 20933442
  9. Johnsen L, Flåtten I, Morigen, Dalhus B, Bjørås M, Waldminghaus T, Skarstad K (2010)
    The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication
    Mol Microbiol, 79 (2), 433-46
    DOI 10.1111/j.1365-2958.2010.07453.x, PubMed 21219462
  10. Johnsen L, Weigel C, von Kries J, Møller M, Skarstad K (2010)
    A novel DNA gyrase inhibitor rescues Escherichia coli dnaAcos mutant cells from lethal hyperinitiation
    J Antimicrob Chemother, 65 (5), 924-30
    DOI 10.1093/jac/dkq071, PubMed 20228083
  11. Klionsky DJ, Seglen PO (2010)
    The Norse god of autophagy. Interviewed by Daniel J Klionsky
    Autophagy, 6 (8), 1017-31
    DOI 10.4161/auto.6.8.13092, PubMed 20814236
  12. Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
    UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
    Autophagy, 6 (7), 863-70
    DOI 10.4161/auto.6.7.13033, PubMed 20724836
  13. Landsverk OJ, Barois N, Gregers TF, Bakke O (2010)
    Invariant chain increases the half-life of MHC II by delaying endosomal maturation
    Immunol Cell Biol, 89 (5), 619-29
    DOI 10.1038/icb.2010.143, PubMed 21116285
  14. Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L, Stenmark H (2010)
    Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes
    Dev Cell, 19 (1), 148-59
    DOI 10.1016/j.devcel.2010.06.010, PubMed 20643357
  15. Lobert VH, Stenmark H (2010)
    Ubiquitination of α-integrin cytoplasmic tails
    Commun Integr Biol, 3 (6), 583-5
    DOI 10.4161/cib.3.6.13176, PubMed 21331246
  16. Malagoli D, Abdalla FC, Cao Y, Feng Q, Fujisaki K, Gregorc A, Matsuo T, Nezis IP, Papassideri IS, Sass M, Silva-Zacarin EC, Tettamanti G, Umemiya-Shirafuji R (2010)
    Autophagy and its physiological relevance in arthropods: current knowledge and perspectives
    Autophagy, 6 (5), 575-88
    DOI 10.4161/auto.6.5.11962, PubMed 20458176
  17. Nezis IP, Sagona AP, Schink KO, Stenmark H (2010)
    Divide and ProsPer: the emerging role of PtdIns3P in cytokinesis
    Trends Cell Biol, 20 (11), 642-9
    DOI 10.1016/j.tcb.2010.08.010, PubMed 20880709
  18. Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
    Autophagy as a trigger for cell death Autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
    Autophagy, 6 (8), 1214-+
    DOI 10.4161/auto.6.8.13694
  19. Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
    Autophagy as a trigger for cell death: autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
    Autophagy, 6 (8), 1214-5
    DOI 10.4161/auto.6.8.13694, PubMed 20935512
  20. Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjørkøy G, Johansen T, Rusten TE, Brech A, Baehrecke EH, Stenmark H (2010)
    Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
    J Cell Biol, 190 (4), 523-31
    DOI 10.1083/jcb.201002035, PubMed 20713604
  21. Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A, Bjørkøy G, Johansen T (2010)
    FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
    J Cell Biol, 188 (2), 253-69
    DOI 10.1083/jcb.200907015, PubMed 20100911
  22. Pust S, Barth H, Sandvig K (2010)
    Clostridium botulinum C2 toxin is internalized by clathrin- and Rho-dependent mechanisms
    Cell Microbiol, 12 (12), 1809-20
    DOI 10.1111/j.1462-5822.2010.01512.x, PubMed 20690924
  23. Pust S, Dyve AB, Torgersen ML, van Deurs B, Sandvig K (2010)
    Interplay between toxin transport and flotillin localization
    PLoS One, 5 (1), e8844
    DOI 10.1371/journal.pone.0008844, PubMed 20107503
  24. Roxrud I, Stenmark H, Malerød L (2010)
    ESCRT & Co
    Biol Cell, 102 (5), 293-318
    DOI 10.1042/BC20090161, PubMed 20222872
  25. Rusten TE, Stenmark H (2010)
    p62, an autophagy hero or culprit?
    Nat Cell Biol, 12 (3), 207-9
    DOI 10.1038/ncb0310-207, PubMed 20190829
  26. Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
    PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
    Nat Cell Biol, 12 (4), 362-71
    DOI 10.1038/ncb2036, PubMed 20208530
  27. Sagona AP, Stenmark H (2010)
    Cytokinesis and cancer (vol 584, pg 2652, 2010)
    FEBS Lett., 584 (18), 4128
    DOI 10.1016/j.febslet.2010.08.016
  28. Sagona AP, Stenmark H (2010)
    Cytokinesis and cancer
    FEBS Lett, 584 (12), 2652-61
    DOI 10.1016/j.febslet.2010.03.044, PubMed 20371245
  29. Sandvig K, Torgersen ML, Engedal N, Skotland T, Iversen TG (2010)
    Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine
    FEBS Lett, 584 (12), 2626-34
    DOI 10.1016/j.febslet.2010.04.008, PubMed 20385131
  30. Seglen PO, Brinchmann MF (2010)
    Purification of autophagosomes from rat hepatocytes
    Autophagy, 6 (4), 542-7
    DOI 10.4161/auto.6.4.11272, PubMed 20505360
  31. Shimokawa N, Haglund K, Hölter SM, Grabbe C, Kirkin V, Koibuchi N, Schultz C, Rozman J, Hoeller D, Qiu CH, Londoño MB, Ikezawa J, Jedlicka P, Stein B, Schwarzacher SW, Wolfer DP, Ehrhardt N, Heuchel R, Nezis I, Brech A, Schmidt MHH, Fuchs H, Gailus-Durner V, Klingenspor M, Bogler O et al. (2010)
    CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice
    EMBO J, 29 (14), 2421-32
    DOI 10.1038/emboj.2010.120, PubMed 20551902
  32. Skotland T, Iversen TG, Sandvig K (2010)
    New metal-based nanoparticles for intravenous use: requirements for clinical success with focus on medical imaging
    Nanomedicine, 6 (6), 730-7
    DOI 10.1016/j.nano.2010.05.002, PubMed 20570639
  33. Stokke C, Waldminghaus T, Skarstad K (2010)
    Replication patterns and organization of replication forks in Vibrio cholerae
    Microbiology (Reading), 157 (Pt 3), 695-708
    DOI 10.1099/mic.0.045112-0, PubMed 21163839
  34. Stuffers S, Malerød L, Schink KO, Corvera S, Stenmark H, Brech A (2010)
    Time-resolved ultrastructural detection of phosphatidylinositol 3-phosphate
    J Histochem Cytochem, 58 (11), 1025-32
    DOI 10.1369/jhc.2010.955815, PubMed 20713985
  35. Teichmann B, Liu L, Schink KO, Bölker M (2010)
    Activation of the ustilagic acid biosynthesis gene cluster in Ustilago maydis by the C2H2 zinc finger transcription factor Rua1
    Appl Environ Microbiol, 76 (8), 2633-40
    DOI 10.1128/AEM.02211-09, PubMed 20173069
  36. Thoresen SB, Pedersen NM, Liestøl K, Stenmark H (2010)
    A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
    Exp Cell Res, 316 (20), 3368-78
    DOI 10.1016/j.yexcr.2010.07.008, PubMed 20643123
  37. Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2010)
    Functional characterization of the protein C A267T mutation: evidence for impaired secretion due to defective intracellular transport
    BMC Cell Biol, 11, 67
    DOI 10.1186/1471-2121-11-67, PubMed 20815936
  38. Torgersen ML, Engedal N, Bergan J, Sandvig K (2010)
    The Intracellular Journey of Shiga Toxins
    The Open Toxinology Journal, 3, 3-12
    PublikaID 24
  39. Torgersen ML, Engedal N, Pedersen AM, Husebye H, Espevik T, Sandvig K (2010)
    Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells
    FEMS Immunol Med Microbiol, 61 (1), 63-75
    DOI 10.1111/j.1574-695X.2010.00749.x, PubMed 21054580
  40. Utskarpen A, Massol R, van Deurs B, Lauvrak SU, Kirchhausen T, Sandvig K (2010)
    Shiga toxin increases formation of clathrin-coated pits through Syk kinase
    PLoS One, 5 (7), e10944
    DOI 10.1371/journal.pone.0010944, PubMed 20668539
  41. Waldminghaus T, Skarstad K (2010)
    ChIP on Chip: surprising results are often artifacts
    BMC Genomics, 11, 414
    DOI 10.1186/1471-2164-11-414, PubMed 20602746

Publications 2009

  1. Bjørkøy G, Lamark T, Pankiv S, Øvervatn A, Brech A, Johansen T (2009)
    Monitoring autophagic degradation of p62/SQSTM1
    Methods Enzymol, 452, 181-97
    DOI 10.1016/S0076-6879(08)03612-4, PubMed 19200883
  2. Boeneman K, Fossum S, Yang Y, Fingland N, Skarstad K, Crooke E (2009)
    Escherichia coli DnaA forms helical structures along the longitudinal cell axis distinct from MreB filaments
    Mol Microbiol, 72 (3), 645-57
    DOI 10.1111/j.1365-2958.2009.06674.x, PubMed 19400775
  3. Boye E, Grallert B (2009)
    In DNA replication, the early bird catches the worm
    Cell, 136 (5), 812-4
    DOI 10.1016/j.cell.2009.02.023, PubMed 19269359
  4. Boye E, Skjølberg HC, Grallert B (2009)
    Checkpoint regulation of DNA replication
    Methods Mol Biol, 521, 55-70
    DOI 10.1007/978-1-60327-815-7_4, PubMed 19563101
  5. Brech A, Ahlquist T, Lothe RA, Stenmark H (2009)
    Autophagy in tumour suppression and promotion
    Mol Oncol, 3 (4), 366-75
    DOI 10.1016/j.molonc.2009.05.007, PubMed 19559660
  6. Dyve AB, Bergan J, Utskarpen A, Sandvig K (2009)
    Sorting nexin 8 regulates endosome-to-Golgi transport
    Biochem Biophys Res Commun, 390 (1), 109-14
    DOI 10.1016/j.bbrc.2009.09.076, PubMed 19782049
  7. Døving KB, Sandvig K, Kasumyan A (2009)
    Ligand-specific induction of endocytosis in taste receptor cells
    J Exp Biol, 212 (Pt 1), 42-9
    DOI 10.1242/jeb.025700, PubMed 19088209
  8. Iversen TG, Frerker N, Sandvig K (2009)
    Quantum dot bioconjugates: uptake into cells and induction of changes in normal cellular transport
    San Jose, CA, USA, SPIE, 1, 7189[1], 71890T-9
    PublikaID 29
  9. Kaiser E, Pust S, Kroll C, Barth H (2009)
    Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells
    Cell Microbiol, 11 (5), 780-95
    DOI 10.1111/j.1462-5822.2009.01291.x, PubMed 19159389
  10. Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
    Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
    J Cell Sci, 122 (Pt 21), 3883-93
    DOI 10.1242/jcs.053801, PubMed 19808888
  11. Malerød L, Stenmark H (2009)
    ESCRTing membrane deformation
    Cell, 136 (1), 15-7
    DOI 10.1016/j.cell.2008.12.029, PubMed 19135881
  12. Morigen, Odsbu I, Skarstad K (2009)
    Growth rate dependent numbers of SeqA structures organize the multiple replication forks in rapidly growing Escherichia coli
    Genes Cells, 14 (5), 643-57
    DOI 10.1111/j.1365-2443.2009.01298.x, PubMed 19371375
  13. Nezis IP, Lamark T, Velentzas AD, Rusten TE, Bjørkøy G, Johansen T, Papassideri IS, Stravopodis DJ, Margaritis LH, Stenmark H, Brech A (2009)
    Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
    Autophagy, 5 (3), 298-302
    DOI 10.4161/auto.5.3.7454, PubMed 19066465
  14. Odsbu I, Morigen, Skarstad K (2009)
    A reduction in ribonucleotide reductase activity slows down the chromosome replication fork but does not change its localization
    PLoS One, 4 (10), e7617
    DOI 10.1371/journal.pone.0007617, PubMed 19898675
  15. Raiborg C, Stenmark H (2009)
    The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
    Nature, 458 (7237), 445-52
    DOI 10.1038/nature07961, PubMed 19325624
  16. Rodahl LM, Haglund K, Sem-Jacobsen C, Wendler F, Vincent JP, Lindmo K, Rusten TE, Stenmark H (2009)
    Disruption of Vps4 and JNK function in Drosophila causes tumour growth
    PLoS One, 4 (2), e4354
    DOI 10.1371/journal.pone.0004354, PubMed 19194501
  17. Rodahl LM, Stuffers S, Lobert VH, Stenmark H (2009)
    The role of ESCRT proteins in attenuation of cell signalling
    Biochem Soc Trans, 37 (Pt 1), 137-42
    DOI 10.1042/BST0370137, PubMed 19143618
  18. Roxrud I, Raiborg C, Gilfillan GD, Strømme P, Stenmark H (2009)
    Dual degradation mechanisms ensure disposal of NHE6 mutant protein associated with neurological disease
    Exp Cell Res, 315 (17), 3014-27
    DOI 10.1016/j.yexcr.2009.07.012, PubMed 19619532
  19. Rusten TE, Stenmark H (2009)
    How do ESCRT proteins control autophagy?
    J Cell Sci, 122 (Pt 13), 2179-83
    DOI 10.1242/jcs.050021, PubMed 19535733
  20. Raa H, Grimmer S, Schwudke D, Bergan J, Wälchli S, Skotland T, Shevchenko A, Sandvig K (2009)
    Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin
    Traffic, 10 (7), 868-82
    DOI 10.1111/j.1600-0854.2009.00919.x, PubMed 19453975
  21. Sandvig K, Bergan J, Dyve AB, Skotland T, Torgersen ML (2009)
    Endocytosis and retrograde transport of Shiga toxin
    Toxicon, 56 (7), 1181-5
    DOI 10.1016/j.toxicon.2009.11.021, PubMed 19951719
  22. Seglen PO, Øverbye A, Saetre F (2009)
    Sequestration assays for mammalian autophagy
    Methods Enzymol, 452, 63-83
    DOI 10.1016/S0076-6879(08)03605-7, PubMed 19200876
  23. Skjølberg HC, Fensgård O, Nilsen H, Grallert B, Boye E (2009)
    Global transcriptional response after exposure of fission yeast cells to ultraviolet light
    BMC Cell Biol, 10, 87
    DOI 10.1186/1471-2121-10-87, PubMed 20015352
  24. Skånland SS, Wälchli S, Brech A, Sandvig K (2009)
    SNX4 in complex with clathrin and dynein: implications for endosome movement
    PLoS One, 4 (6), e5935
    DOI 10.1371/journal.pone.0005935, PubMed 19529763
  25. Skånland SS, Wälchli S, Sandvig K (2009)
    β-arrestins attenuate p38-mediated endosome to Golgi transport
    Cell Microbiol, 11 (5), 796-807
    DOI 10.1111/j.1462-5822.2009.01292.x, PubMed 19159388
  26. Stenmark H (2009)
    Rab GTPases as coordinators of vesicle traffic
    Nat Rev Mol Cell Biol, 10 (8), 513-25
    DOI 10.1038/nrm2728, PubMed 19603039
  27. Stenmark H (2009)
    Seeing is believing
    Nat Rev Mol Cell Biol, 10 (9), 582
    DOI 10.1038/nrm2747, PubMed 19702012
  28. Stepankiw N, Kaidow A, Boye E, Bates D (2009)
    The right half of the Escherichia coli replication origin is not essential for viability, but facilitates multi-forked replication
    Mol Microbiol, 74 (2), 467-79
    DOI 10.1111/j.1365-2958.2009.06877.x, PubMed 19737351
  29. Stuffers S, Sem Wegner C, Stenmark H, Brech A (2009)
    Multivesicular endosome biogenesis in the absence of ESCRTs
    Traffic, 10 (7), 925-37
    DOI 10.1111/j.1600-0854.2009.00920.x, PubMed 19490536
  30. Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D (2009)
    Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
    J Cell Sci, 122 (Pt 14), 2413-23
    DOI 10.1242/jcs.046391, PubMed 19571114
  31. Waldminghaus T, Skarstad K (2009)
    The Escherichia coli SeqA protein
    Plasmid, 61 (3), 141-50
    DOI 10.1016/j.plasmid.2009.02.004, PubMed 19254745
  32. Wang J, Morigen (2009)
    BayesPI - a new model to study protein-DNA interactions: a case study of condition-specific protein binding parameters for Yeast transcription factors
    BMC Bioinformatics, 10, 345
    DOI 10.1186/1471-2105-10-345, PubMed 19857274
  33. Wegner CS, Malerød L, Pedersen NM, Progida C, Bakke O, Stenmark H, Brech A (2009)
    Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
    Histochem Cell Biol, 133 (1), 41-55
    DOI 10.1007/s00418-009-0643-8, PubMed 19830447
  34. Wälchli S, Aasheim HC, Skånland SS, Spilsberg B, Torgersen ML, Rosendal KR, Sandvig K (2009)
    Characterization of clathrin and Syk interaction upon Shiga toxin binding
    Cell Signal, 21 (7), 1161-8
    DOI 10.1016/j.cellsig.2009.03.005, PubMed 19289168
  35. Zakrzewska M, Wiedlocha A, Szlachcic A, Krowarsch D, Otlewski J, Olsnes S (2009)
    Increased protein stability of FGF1 can compensate for its reduced affinity for heparin
    J Biol Chem, 284 (37), 25388-403
    DOI 10.1074/jbc.M109.001289, PubMed 19574212
  36. Zakrzewska M, Zhen Y, Wiedlocha A, Olsnes S, Wesche J (2009)
    Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane
    Biochemistry, 48 (30), 7209-18
    DOI 10.1021/bi9007353, PubMed 19558187
  37. Zheng YT, Shahnazari S, Brech A, Lamark T, Johansen T, Brumell JH (2009)
    The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway
    J Immunol, 183 (9), 5909-16
    DOI 10.4049/jimmunol.0900441, PubMed 19812211
  38. Øverbye A, Seglen PO (2009)
    Phosphorylated and non-phosphorylated forms of catechol O-methyltransferase in rat liver, brain and other tissues
    Biochem J, 417 (2), 535-45
    DOI 10.1042/BJ20081284, PubMed 18831714

Publications 2008

  1. Bach T, Morigen, Skarstad K (2008)
    The initiator protein DnaA contributes to keeping new origins inactivated by promoting the presence of hemimethylated DNA
    J Mol Biol, 384 (5), 1076-85
    DOI 10.1016/j.jmb.2008.09.042, PubMed 18835566
  2. Bergeland T, Haugen L, Landsverk OJ, Stenmark H, Bakke O (2008)
    Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1
    EMBO Rep, 9 (2), 171-8
    DOI 10.1038/sj.embor.7401152, PubMed 18188183
  3. Bøe CA, Garcia I, Pai CC, Sharom JR, Skjølberg HC, Boye E, Kearsey S, Macneill SA, Tyers MD, Grallert B (2008)
    Rapid regulation of protein activity in fission yeast
    BMC Cell Biol, 9, 23
    DOI 10.1186/1471-2121-9-23, PubMed 18457584
  4. Cumming RC, Simonsen A, Finley KD (2008)
    Quantitative analysis of autophagic activity in Drosophila neural tissues by measuring the turnover rates of pathway substrates
    Methods Enzymol, 451, 639-51
    DOI 10.1016/S0076-6879(08)03235-7, PubMed 19185743
  5. Engedal N, Auberger P, Blomhoff HK (2008)
    Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly
    J Leukoc Biol, 85 (3), 469-80
    DOI 10.1189/jlb.1107790, PubMed 19112091
  6. Flåtten I, Morigen, Skarstad K (2008)
    DnaA protein interacts with RNA polymerase and partially protects it from the effect of rifampicin
    Mol Microbiol, 71 (4), 1018-30
    DOI 10.1111/j.1365-2958.2008.06585.x, PubMed 19170875
  7. Fossum S, De Pascale G, Weigel C, Messer W, Donadio S, Skarstad K (2008)
    A robust screen for novel antibiotics: specific knockout of the initiator of bacterial DNA replication
    FEMS Microbiol Lett, 281 (2), 210-4
    DOI 10.1111/j.1574-6968.2008.01103.x, PubMed 18312360
  8. Fuller RS (2008)
    A tribute to Arthur Kornberg 1918-2007
    Nat Struct Mol Biol, 15 (1), 2-17
    DOI 10.1038/nsmb0108-2, PubMed 18176549
  9. Gilfillan GD, Selmer KK, Roxrud I, Smith R, Kyllerman M, Eiklid K, Kroken M, Mattingsdal M, Egeland T, Stenmark H, Sjøholm H, Server A, Samuelsson L, Christianson A, Tarpey P, Whibley A, Stratton MR, Futreal PA, Teague J, Edkins S, Gecz J, Turner G, Raymond FL, Schwartz C, Stevenson RE et al. (2008)
    SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome
    Am J Hum Genet, 82 (4), 1003-10
    DOI 10.1016/j.ajhg.2008.01.013, PubMed 18342287
  10. Grallert B, Boye E (2008)
    The multiple facets of the intra-S checkpoint
    Cell Cycle, 7 (15), 2315-20
    DOI 10.4161/cc.6389, PubMed 18677104
  11. Grosso S, Volta V, Sala LA, Vietri M, Marchisio PC, Ron D, Biffo S (2008)
    PKCbetaII modulates translation independently from mTOR and through RACK1
    Biochem J, 415 (1), 77-85
    DOI 10.1042/BJ20080463, PubMed 18557705
  12. Grosso S, Volta V, Vietri M, Gorrini C, Marchisio PC, Biffo S (2008)
    Eukaryotic ribosomes host PKC activity
    Biochem Biophys Res Commun, 376 (1), 65-9
    DOI 10.1016/j.bbrc.2008.08.118, PubMed 18768137
  13. Haugsten EM, Malecki J, Bjørklund SM, Olsnes S, Wesche J (2008)
    Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis
    Mol Biol Cell, 19 (8), 3390-403
    DOI 10.1091/mbc.e07-12-1219, PubMed 18480409
  14. Heine K, Pust S, Enzenmüller S, Barth H (2008)
    ADP-ribosylation of actin by the Clostridium botulinum C2 toxin in mammalian cells results in delayed caspase-dependent apoptotic cell death
    Infect Immun, 76 (10), 4600-8
    DOI 10.1128/IAI.00651-08, PubMed 18710868
  15. Klionsky DJ, Elazar Z, Seglen PO, Rubinsztein DC (2008)
    Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?
    Autophagy, 4 (7), 849-50
    DOI 10.4161/auto.6845, PubMed 18758232
  16. Krohn M, Skjølberg HC, Soltani H, Grallert B, Boye E (2008)
    The G1-S checkpoint in fission yeast is not a general DNA damage checkpoint
    J Cell Sci, 121 (Pt 24), 4047-54
    DOI 10.1242/jcs.035428, PubMed 19033384
  17. Lindmo K, Brech A, Finley KD, Gaumer S, Contamine D, Rusten TE, Stenmark H (2008)
    The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
    Autophagy, 4 (4), 500-6
    DOI 10.4161/auto.5829, PubMed 18326940
  18. Miaczynska M, Stenmark H (2008)
    Mechanisms and functions of endocytosis
    J Cell Biol, 180 (1), 7-11
    DOI 10.1083/jcb.200711073, PubMed 18195098
  19. Morrison HA, Dionne H, Rusten TE, Brech A, Fisher WW, Pfeiffer BD, Celniker SE, Stenmark H, Bilder D (2008)
    Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45
    Mol Biol Cell, 19 (10), 4167-76
    DOI 10.1091/mbc.e08-07-0716, PubMed 18685079
  20. Nezis IP, Papassideri I (2008)
    Monitoring autophagy in insect eggs
    Methods Enzymol, 451, 669-83
    DOI 10.1016/S0076-6879(08)03237-0, PubMed 19185745
  21. Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A (2008)
    Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
    J Cell Biol, 180 (6), 1065-71
    DOI 10.1083/jcb.200711108, PubMed 18347073
  22. Raposo G, Stenmark H (2008)
    Membranes and organelles
    Curr Opin Cell Biol, 20 (4), 357-9
    DOI 10.1016/j.ceb.2008.06.005, PubMed 18588977
  23. Rusten TE, Filimonenko M, Rodahl LM, Stenmark H, Simonsen A (2008)
    ESCRTing autophagic clearance of aggregating proteins
    Autophagy, 4 (2), 233-236
    DOI 10.4161/auto.5396
  24. Rusten TE, Simonsen A (2008)
    ESCRT functions in autophagy and associated disease
    Cell Cycle, 7 (9), 1166-72
    DOI 10.4161/cc.7.9.5784, PubMed 18418046
  25. Sandvig K, Torgersen ML, Raa HA, van Deurs B (2008)
    Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity
    Histochem Cell Biol, 129 (3), 267-76
    DOI 10.1007/s00418-007-0376-5, PubMed 18193449
  26. Sandvig K, van Deurs B (2008)
    Cell biology: Viruses in camouflage
    Nature, 453 (7194), 466-7
    DOI 10.1038/453466a, PubMed 18497813
  27. Simonsen A, Stenmark H (2008)
    Self-eating from an ER-associated cup
    J Cell Biol, 182 (4), 621-2
    DOI 10.1083/jcb.200807061, PubMed 18725534
  28. Stuffers S, Brech A, Stenmark H (2008)
    ESCRT proteins in physiology and disease
    Exp Cell Res, 315 (9), 1619-26
    DOI 10.1016/j.yexcr.2008.10.013, PubMed 19013455
  29. Sørensen V, Zhen Y, Zakrzewska M, Haugsten EM, Wälchli S, Nilsen T, Olsnes S, Wiedlocha A (2008)
    Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus
    Mol Cell Biol, 28 (12), 4129-41
    DOI 10.1128/MCB.02117-07, PubMed 18411303
  30. Tekle C, Deurs Bv, Sandvig K, Iversen TG (2008)
    Cellular trafficking of quantum dot-ligand bioconjugates and their induction of changes in normal routing of unconjugated ligands
    Nano Lett, 8 (7), 1858-65
    DOI 10.1021/nl0803848, PubMed 18570482
  31. Umebayashi K, Stenmark H, Yoshimori T (2008)
    Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
    Mol Biol Cell, 19 (8), 3454-62
    DOI 10.1091/mbc.e07-10-0988, PubMed 18508924
  32. Zakrzewska M, Marcinkowska E, Wiedlocha A (2008)
    FGF-1: from biology through engineering to potential medical applications
    Crit Rev Clin Lab Sci, 45 (1), 91-135
    DOI 10.1080/10408360701713120, PubMed 18293181

Publications 2007

  1. Bertelsen V, Breen K, Sandvig K, Stang E, Madshus IH (2007)
    The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis
    Exp Cell Res, 313 (8), 1696-709
    DOI 10.1016/j.yexcr.2007.02.017, PubMed 17382318
  2. Citores L, Bai L, Sørensen V, Olsnes S (2007)
    Fibroblast growth factor receptor-induced phosphorylation of STAT1 at the Golgi apparatus without translocation to the nucleus
    J Cell Physiol, 212 (1), 148-56
    DOI 10.1002/jcp.21014, PubMed 17311277
  3. Feugaing DD, Tammi R, Echtermeyer FG, Stenmark H, Kresse H, Smollich M, Schönherr E, Kiesel L, Götte M (2007)
    Endocytosis of the dermatan sulfate proteoglycan decorin utilizes multiple pathways and is modulated by epidermal growth factor receptor signaling
    Biochimie, 89 (5), 637-57
    DOI 10.1016/j.biochi.2006.12.012, PubMed 17335953
  4. Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A (2007)
    Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
    J Cell Biol, 179 (3), 485-500
    DOI 10.1083/jcb.200702115, PubMed 17984323
  5. Fort J, de la Ballina LR, Burghardt HE, Ferrer-Costa C, Turnay J, Ferrer-Orta C, Usón I, Zorzano A, Fernández-Recio J, Orozco M, Lizarbe MA, Fita I, Palacín M (2007)
    The structure of human 4F2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane
    J Biol Chem, 282 (43), 31444-52
    DOI 10.1074/jbc.M704524200, PubMed 17724034
  6. Fossum S, Crooke E, Skarstad K (2007)
    Organization of sister origins and replisomes during multifork DNA replication in Escherichia coli
    EMBO J, 26 (21), 4514-22
    DOI 10.1038/sj.emboj.7601871, PubMed 17914458
  7. Grallert B, Boye E (2007)
    The Gcn2 kinase as a cell cycle regulator
    Cell Cycle, 6 (22), 2768-72
    DOI 10.4161/cc.6.22.4933, PubMed 17986863
  8. Haglund K, Rusten TE, Stenmark H (2007)
    Aberrant receptor signaling and trafficking as mechanisms in oncogenesis
    Crit Rev Oncog, 13 (1), 39-74
    DOI 10.1615/critrevoncog.v13.i1.20, PubMed 17956217
  9. Hughes T, Rusten TE (2007)
    Origin and evolution of self-consumption: autophagy
    Adv Exp Med Biol, 607, 111-8
    DOI 10.1007/978-0-387-74021-8_9, PubMed 17977463
  10. Klionsky DJ, Cuervo AM, Dunn WA, Levine B, van der Klei I, Seglen PO (2007)
    How shall I eat thee?
    Autophagy, 3 (5), 413-6
    DOI 10.4161/auto.4377, PubMed 17568180
  11. Kurmanova A, Llorente A, Polesskaya A, Garred O, Olsnes S, Kozlov J, Sandvig K (2007)
    Structural requirements for furin-induced cleavage and activation of Shiga toxin
    Biochem Biophys Res Commun, 357 (1), 144-9
    DOI 10.1016/j.bbrc.2007.03.110, PubMed 17407762
  12. Llorente A, van Deurs B, Sandvig K (2007)
    Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells
    Eur J Cell Biol, 86 (7), 405-15
    DOI 10.1016/j.ejcb.2007.05.001, PubMed 17601634
  13. Malerød L, Stenmark H (2007)
    ESCRTs
    Curr Biol, 17 (2), R42-3
    DOI 10.1016/j.cub.2006.12.009, PubMed 17240322
  14. Malerød L, Stuffers S, Brech A, Stenmark H (2007)
    Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation
    Traffic, 8 (11), 1617-29
    DOI 10.1111/j.1600-0854.2007.00630.x, PubMed 17714434
  15. Martín-Acebes MA, González-Magaldi M, Sandvig K, Sobrino F, Armas-Portela R (2007)
    Productive entry of type C foot-and-mouth disease virus into susceptible cultured cells requires clathrin and is dependent on the presence of plasma membrane cholesterol
    Virology, 369 (1), 105-18
    DOI 10.1016/j.virol.2007.07.021, PubMed 17714753
  16. Nilsen T, Rosendal KR, Sørensen V, Wesche J, Olsnes S, Wiedłocha A (2007)
    A nuclear export sequence located on a beta-strand in fibroblast growth factor-1
    J Biol Chem, 282 (36), 26245-56
    DOI 10.1074/jbc.M611234200, PubMed 17616529
  17. Norris V, den Blaauwen T, Cabin-Flaman A, Doi RH, Harshey R, Janniere L, Jimenez-Sanchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Saier M, Skarstad K (2007)
    Functional taxonomy of bacterial hyperstructures
    Microbiol Mol Biol Rev, 71 (1), 230-53
    DOI 10.1128/MMBR.00035-06, PubMed 17347523
  18. Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T (2007)
    p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    J Biol Chem, 282 (33), 24131-45
    DOI 10.1074/jbc.M702824200, PubMed 17580304
  19. Progida C, Malerød L, Stuffers S, Brech A, Bucci C, Stenmark H (2007)
    RILP is required for the proper morphology and function of late endosomes
    J Cell Sci, 120 (Pt 21), 3729-37
    DOI 10.1242/jcs.017301, PubMed 17959629
  20. Raiborg C, Malerød L, Pedersen NM, Stenmark H (2007)
    Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
    Exp Cell Res, 314 (4), 801-13
    DOI 10.1016/j.yexcr.2007.10.014, PubMed 18031739
  21. Rusten TE, Stenmark H (2007)
    Developmental biology: moonlighting at the pole
    Nature, 445 (7127), 497-9
    DOI 10.1038/445497a, PubMed 17268460
  22. Rusten TE, Vaccari T, Lindmo K, Rodahl LM, Nezis IP, Sem-Jacobsen C, Wendler F, Vincent JP, Brech A, Bilder D, Stenmark H (2007)
    ESCRTs and Fab1 regulate distinct steps of autophagy
    Curr Biol, 17 (20), 1817-25
    DOI 10.1016/j.cub.2007.09.032, PubMed 17935992
  23. Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD (2007)
    Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
    Autophagy, 4 (2), 176-84
    DOI 10.4161/auto.5269, PubMed 18059160
  24. Simonsen A, Cumming RC, Lindmo K, Galaviz V, Cheng S, Rusten TE, Finley KD (2007)
    Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles
    Genetics, 176 (2), 1283-97
    DOI 10.1534/genetics.106.065011, PubMed 17435236
  25. Simonsen A, Stenmark H (2007)
    Stimulating the cell's appetite for itself
    Nat Chem Biol, 3 (6), 304-6
    DOI 10.1038/nchembio0607-304, PubMed 17510644
  26. Skånland SS, Wälchli S, Utskarpen A, Wandinger-Ness A, Sandvig K (2007)
    Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins
    Traffic, 8 (3), 297-309
    DOI 10.1111/j.1600-0854.2006.00527.x, PubMed 17319803
  27. Spilsberg B, Llorente A, Sandvig K (2007)
    Polyunsaturated fatty acids regulate Shiga toxin transport
    Biochem Biophys Res Commun, 364 (2), 283-8
    DOI 10.1016/j.bbrc.2007.09.126, PubMed 17942073
  28. Torgersen ML, Wälchli S, Grimmer S, Skånland SS, Sandvig K (2007)
    Protein kinase Cdelta is activated by Shiga toxin and regulates its transport
    J Biol Chem, 282 (22), 16317-28
    DOI 10.1074/jbc.M610886200, PubMed 17403690
  29. Tvegård T, Soltani H, Skjølberg HC, Krohn M, Nilssen EA, Kearsey SE, Grallert B, Boye E (2007)
    A novel checkpoint mechanism regulating the G1/S transition
    Genes Dev, 21 (6), 649-54
    DOI 10.1101/gad.421807, PubMed 17369398
  30. Utskarpen A, Slagsvold HH, Dyve AB, Skånland SS, Sandvig K (2007)
    SNX1 and SNX2 mediate retrograde transport of Shiga toxin
    Biochem Biophys Res Commun, 358 (2), 566-70
    DOI 10.1016/j.bbrc.2007.04.159, PubMed 17498660
  31. Zhen Y, Sørensen V, Jin Y, Suo Z, Wiedłocha A (2007)
    Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
    Oncogene, 26 (44), 6372-85
    DOI 10.1038/sj.onc.1210473, PubMed 17533378
  32. Øverbye A, Fengsrud M, Seglen PO (2007)
    Proteomic analysis of membrane-associated proteins from rat liver autophagosomes
    Autophagy, 3 (4), 300-22
    DOI 10.4161/auto.3910, PubMed 17377489

Publications 2006

  1. Bache KG (2006)
    The function of ubiquitin-binding protein complexes in endocytic downregulation of growth factor receptors
    Crit Rev Oncog, 12 (3-4), 301; discussion 301-2
    DOI 10.1615/critrevoncog.v12.i3-4.90, PubMed 17425510
  2. Bache KG, Stuffers S, Malerød L, Slagsvold T, Raiborg C, Lechardeur D, Wälchli S, Lukacs GL, Brech A, Stenmark H (2006)
    The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
    Mol Biol Cell, 17 (6), 2513-23
    DOI 10.1091/mbc.e05-10-0915, PubMed 16554368
  3. Boye E (2006)
    DisA, a busy bee that monitors chromosome integrity
    Cell, 125 (4), 641-3
    DOI 10.1016/j.cell.2006.05.004, PubMed 16713555
  4. Cabezas A, Pattni K, Stenmark H (2006)
    Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
    Gene, 371 (1), 34-41
    DOI 10.1016/j.gene.2005.11.009, PubMed 16448788
  5. Gon S, Camara JE, Klungsøyr HK, Crooke E, Skarstad K, Beckwith J (2006)
    A novel regulatory mechanism couples deoxyribonucleotide synthesis and DNA replication in Escherichia coli
    EMBO J, 25 (5), 1137-47
    DOI 10.1038/sj.emboj.7600990, PubMed 16482221
  6. Grimmer S, Spilsberg B, Hanada K, Sandvig K (2006)
    Depletion of sphingolipids facilitates endosome to Golgi transport of ricin
    Traffic, 7 (9), 1243-53
    DOI 10.1111/j.1600-0854.2006.00456.x, PubMed 16919154
  7. Haglund K, Stenmark H (2006)
    Working out coupled monoubiquitination
    Nat Cell Biol, 8 (11), 1218-9
    DOI 10.1038/ncb1106-1218, PubMed 17077855
  8. Hecker CM, Rabiller M, Haglund K, Bayer P, Dikic I (2006)
    Specification of SUMO1- and SUMO2-interacting motifs
    J Biol Chem, 281 (23), 16117-27
    DOI 10.1074/jbc.M512757200, PubMed 16524884
  9. Hirano S, Kawasaki M, Ura H, Kato R, Raiborg C, Stenmark H, Wakatsuki S (2006)
    Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
    Nat Struct Mol Biol, 13 (3), 272-7
    DOI 10.1038/nsmb1051, PubMed 16462748
  10. Hirano S, Suzuki N, Slagsvold T, Kawasaki M, Trambaiolo D, Kato R, Stenmark H, Wakatsuki S (2006)
    Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain
    Nat Struct Mol Biol, 13 (11), 1031-2
    DOI 10.1038/nsmb1163, PubMed 17057714
  11. Hoeller D, Crosetto N, Blagoev B, Raiborg C, Tikkanen R, Wagner S, Kowanetz K, Breitling R, Mann M, Stenmark H, Dikic I (2006)
    Regulation of ubiquitin-binding proteins by monoubiquitination
    Nat Cell Biol, 8 (2), 163-9
    DOI 10.1038/ncb1354, PubMed 16429130
  12. Hollås H, Aukrust I, Grimmer S, Strand E, Flatmark T, Vedeler A (2006)
    Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA
    Biochim Biophys Acta, 1763 (11), 1325-34
    DOI 10.1016/j.bbamcr.2006.08.043, PubMed 17045350
  13. Husebye H, Halaas Ø, Stenmark H, Tunheim G, Sandanger Ø, Bogen B, Brech A, Latz E, Espevik T (2006)
    Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
    EMBO J, 25 (4), 683-92
    DOI 10.1038/sj.emboj.7600991, PubMed 16467847
  14. Huynh T, Wälchli S, Sioud M (2006)
    Transcriptional targeting of small interfering RNAs into cancer cells
    Biochem Biophys Res Commun, 350 (4), 854-9
    DOI 10.1016/j.bbrc.2006.09.127, PubMed 17034763
  15. Johannessen LE, Pedersen NM, Pedersen KW, Madshus IH, Stang E (2006)
    Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits
    Mol Cell Biol, 26 (2), 389-401
    DOI 10.1128/MCB.26.2.389-401.2006, PubMed 16382132
  16. Kazazic M, Roepstorff K, Johannessen LE, Pedersen NM, van Deurs B, Stang E, Madshus IH (2006)
    EGF-induced activation of the EGF receptor does not trigger mobilization of caveolae
    Traffic, 7 (11), 1518-27
    DOI 10.1111/j.1600-0854.2006.00487.x, PubMed 16984407
  17. Khnykin D, Olsnes S (2006)
    Reduced binding of FGF1 to mutant fibroblast growth factor receptor 3
    Growth Factors, 24 (2), 111-9
    DOI 10.1080/08977190600621388, PubMed 16801131
  18. Klokk TI, Kurys P, Elbi C, Nagaich AK, Hendarwanto A, Slagsvold T, Chang CY, Hager GL, Saatcioglu F (2006)
    Ligand-specific dynamics of the androgen receptor at its response element in living cells
    Mol Cell Biol, 27 (5), 1823-43
    DOI 10.1128/MCB.01297-06, PubMed 17189428
  19. Leithe E, Brech A, Rivedal E (2006)
    Endocytic processing of connexin43 gap junctions: a morphological study
    Biochem J, 393 (Pt 1), 59-67
    DOI 10.1042/BJ20050674, PubMed 16162097
  20. Lindmo K, Simonsen A, Brech A, Finley K, Rusten TE, Stenmark H (2006)
    A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
    Exp Cell Res, 312 (11), 2018-27
    DOI 10.1016/j.yexcr.2006.03.002, PubMed 16600212
  21. Lindmo K, Stenmark H (2006)
    Regulation of membrane traffic by phosphoinositide 3-kinases
    J Cell Sci, 119 (Pt 4), 605-14
    DOI 10.1242/jcs.02855, PubMed 16467569
  22. Lindmo K, Stenmark H (2006)
    How a RING finger protein and a steroid hormone control autophagy
    Autophagy, 2 (4), 321-2
    DOI 10.4161/auto.3091, PubMed 16874068
  23. Marcinkowska E, Superat K, Wiedłocha A (2006)
    FGF-1 as a possible carrier for targeted drug delivery
    Oncol Res, 16 (1), 27-34
    DOI 10.3727/000000006783981242, PubMed 16783965
  24. Michaelsen TE, Thommesen JE, Ihle O, Gregers TF, Sandin RH, Brekke OH, Sandlie I (2006)
    A mutant human IgG molecule with only one C1q binding site can activate complement and induce lysis of target cells
    Eur J Immunol, 36 (1), 129-38
    DOI 10.1002/eji.200535178, PubMed 16323243
  25. Myromslien FD, Grøvdal LM, Raiborg C, Stenmark H, Madshus IH, Stang E (2006)
    Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
    Exp Cell Res, 312 (16), 3036-48
    DOI 10.1016/j.yexcr.2006.06.004, PubMed 16859684
  26. Norlén L, Gil IP, Simonsen A, Descouts P (2006)
    Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films
    J Struct Biol, 158 (3), 386-400
    DOI 10.1016/j.jsb.2006.12.006, PubMed 17287132
  27. Raiborg C (2006)
    Hrs makes receptors silent: a key to endosomal protein sorting
    Crit Rev Oncog, 12 (3-4), 295, discussion 295-6
    DOI 10.1615/critrevoncog.v12.i3-4.70, PubMed 17425508
  28. Raiborg C, Slagsvold T, Stenmark H (2006)
    A new side to ubiquitin
    Trends Biochem Sci, 31 (10), 541-4
    DOI 10.1016/j.tibs.2006.07.009, PubMed 16901703
  29. Raiborg C, Wesche J, Malerød L, Stenmark H (2006)
    Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
    J Cell Sci, 119 (Pt 12), 2414-24
    DOI 10.1242/jcs.02978, PubMed 16720641
  30. Ralph E, Boye E, Kearsey SE (2006)
    DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1
    EMBO Rep, 7 (11), 1134-9
    DOI 10.1038/sj.embor.7400827, PubMed 17039252
  31. Rusten TE, Rodahl LM, Pattni K, Englund C, Samakovlis C, Dove S, Brech A, Stenmark H (2006)
    Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
    Mol Biol Cell, 17 (9), 3989-4001
    DOI 10.1091/mbc.e06-03-0239, PubMed 16837550
  32. Rusten TE, Stenmark H (2006)
    Analyzing phosphoinositides and their interacting proteins
    Nat Methods, 3 (4), 251-8
    DOI 10.1038/nmeth867, PubMed 16554828
  33. Rutherford AC, Traer C, Wassmer T, Pattni K, Bujny MV, Carlton JG, Stenmark H, Cullen PJ (2006)
    The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
    J Cell Sci, 119 (Pt 19), 3944-57
    DOI 10.1242/jcs.03153, PubMed 16954148
  34. Shahzidi S, Stokke T, Soltani H, Nesland JM, Peng Q (2006)
    Induction of apoptosis by hexaminolevulinate-mediated photodynamic therapy in human colon carcinoma cell line 320DM
    J Environ Pathol Toxicol Oncol, 25 (1-2), 159-71
    DOI 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.90, PubMed 16566715
  35. Slagsvold T, Marchese A, Brech A, Stenmark H (2006)
    CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
    EMBO J, 25 (16), 3738-49
    DOI 10.1038/sj.emboj.7601267, PubMed 16888620
  36. Slagsvold T, Pattni K, Malerød L, Stenmark H (2006)
    Endosomal and non-endosomal functions of ESCRT proteins
    Trends Cell Biol, 16 (6), 317-26
    DOI 10.1016/j.tcb.2006.04.004, PubMed 16716591
  37. Slominska-Wojewodzka M, Gregers TF, Wälchli S, Sandvig K (2006)
    EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol
    Mol Biol Cell, 17 (4), 1664-75
    DOI 10.1091/mbc.e05-10-0961, PubMed 16452630
  38. Sørensen V, Nilsen T, Wiedłocha A (2006)
    Functional diversity of FGF-2 isoforms by intracellular sorting
    Bioessays, 28 (5), 504-14
    DOI 10.1002/bies.20405, PubMed 16615083
  39. Sørensen V, Wiedlocha A, Haugsten EM, Khnykin D, Wesche J, Olsnes S (2006)
    Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail
    J Cell Sci, 119 (Pt 20), 4332-41
    DOI 10.1242/jcs.03209, PubMed 17003104
  40. Utskarpen A, Slagsvold HH, Iversen TG, Wälchli S, Sandvig K (2006)
    Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'
    Traffic, 7 (6), 663-72
    DOI 10.1111/j.1600-0854.2006.00418.x, PubMed 16683916
  41. Wesche J, Małecki J, Wiedłocha A, Skjerpen CS, Claus P, Olsnes S (2006)
    FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus
    J Biol Chem, 281 (16), 11405-12
    DOI 10.1074/jbc.M600477200, PubMed 16495214
  42. Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2006)
    Structural requirements of FGF-1 for receptor binding and translocation into cells
    Biochemistry, 45 (51), 15338-48
    DOI 10.1021/bi0618114, PubMed 17176056

Publications 2005

  1. Bach T, Skarstad K (2005)
    An oriC-like distribution of GATC sites mediates full sequestration of non-origin sequences in Escherichia coli
    J Mol Biol, 350 (1), 7-11
    DOI 10.1016/j.jmb.2005.04.055, PubMed 15922360
  2. Bates D, Epstein J, Boye E, Fahrner K, Berg H, Kleckner N (2005)
    The Escherichia coli baby cell column: a novel cell synchronization method provides new insight into the bacterial cell cycle
    Mol Microbiol, 57 (2), 380-91
    DOI 10.1111/j.1365-2958.2005.04693.x, PubMed 15978072
  3. Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T (2005)
    p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    J Cell Biol, 171 (4), 603-14
    DOI 10.1083/jcb.200507002, PubMed 16286508
  4. Cabezas A, Bache KG, Brech A, Stenmark H (2005)
    Alix regulates cortical actin and the spatial distribution of endosomes
    J Cell Sci, 118 (Pt 12), 2625-35
    DOI 10.1242/jcs.02382, PubMed 15914539
  5. Canales J, Cabezas A, Pinto RM, Cameselle JC (2005)
    Fluorimetric HPLC detection of endogenous riboflavin 4',5'-cyclic phosphate in rat liver at nanomolar concentrations
    Anal Biochem, 341 (2), 214-9
    DOI 10.1016/j.ab.2005.01.060, PubMed 15907866
  6. Drevon T, Slagsvold T (2005)
    When and from whom do female pied flycatchers (Ficedula hypoleuca) solicit copulations
    Behaviour, 142, 1059-1076
    DOI 10.1163/156853905774405335
  7. Grimmer S, Ying M, Wälchli S, van Deurs B, Sandvig K (2005)
    Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism
    Traffic, 6 (2), 144-56
    DOI 10.1111/j.1600-0854.2005.00258.x, PubMed 15634214
  8. Guerra L, Teter K, Lilley BN, Stenerlöw B, Holmes RK, Ploegh HL, Sandvig K, Thelestam M, Frisan T (2005)
    Cellular internalization of cytolethal distending toxin: a new end to a known pathway
    Cell Microbiol, 7 (7), 921-34
    DOI 10.1111/j.1462-5822.2005.00520.x, PubMed 15953025
  9. Haugsten EM, Sørensen V, Brech A, Olsnes S, Wesche J (2005)
    Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors
    J Cell Sci, 118 (Pt 17), 3869-81
    DOI 10.1242/jcs.02509, PubMed 16091423
  10. Hetz C, Russelakis-Carneiro M, Wälchli S, Carboni S, Vial-Knecht E, Maundrell K, Castilla J, Soto C (2005)
    The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity
    J Neurosci, 25 (11), 2793-802
    DOI 10.1523/JNEUROSCI.4090-04.2005, PubMed 15772339
  11. Hoepfner S, Severin F, Cabezas A, Habermann B, Runge A, Gillooly D, Stenmark H, Zerial M (2005)
    Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B
    Cell, 121 (3), 437-50
    DOI 10.1016/j.cell.2005.02.017, PubMed 15882625
  12. Hommelgaard AM, Roepstorff K, Vilhardt F, Torgersen ML, Sandvig K, van Deurs B (2005)
    Caveolae: stable membrane domains with a potential for internalization
    Traffic, 6 (9), 720-4
    DOI 10.1111/j.1600-0854.2005.00314.x, PubMed 16101676
  13. Høiseth G, Olsnes S (2005)
    [Ricin--a therapeutic agent and a biological weapon]
    Tidsskr Nor Laegeforen, 125 (18), 2477-9
    PubMed 16186864
  14. Ibrahim SO, Miron T, Krohn M, Amaratunga AN, Warnakulasauriya S, Vasstrand EN (2005)
    Tumour-associated Proteins in Oral Squamous Cell Carcinomas by Proteomics
    Cancer Genomics Proteomics, 2 (6), 353-363
    PubMed 31394652
  15. Johannessen LE, Slagsvold T, Hansen BT, Lifjeld JT (2005)
    Manipulation of male quality in wild tits: effects on paternity loss
    Behav. Ecol., 16 (4), 747-754
    DOI 10.1093/beheco/ari048
  16. Korobko E, Kiselev S, Olsnes S, Stenmark H, Korobko I (2005)
    The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5delta differ in their ability to interact with the small GTPase Rab4
    FEBS J, 272 (1), 37-46
    DOI 10.1111/j.1742-4658.2004.04387.x, PubMed 15634330
  17. Lauvrak SU, Wälchli S, Iversen TG, Slagsvold HH, Torgersen ML, Spilsberg B, Sandvig K (2005)
    Shiga toxin regulates its entry in a Syk-dependent manner
    Mol Biol Cell, 17 (3), 1096-109
    DOI 10.1091/mbc.e05-08-0766, PubMed 16371508
  18. Lindstad RI, Sylte I, Mikalsen SO, Seglen PO, Berg E, Winberg JO (2005)
    Pancreatic trypsin activates human promatrix metalloproteinase-2
    J Mol Biol, 350 (4), 682-98
    DOI 10.1016/j.jmb.2005.05.018, PubMed 15950241
  19. Longva KE, Pedersen NM, Haslekås C, Stang E, Madshus IH (2005)
    Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2
    Int J Cancer, 116 (3), 359-67
    DOI 10.1002/ijc.21015, PubMed 15800944
  20. Morigen, Molina F, Skarstad K (2005)
    Deletion of the datA site does not affect once-per-cell-cycle timing but induces rifampin-resistant replication
    J Bacteriol, 187 (12), 3913-20
    DOI 10.1128/JB.187.12.3913-3920.2005, PubMed 15939703
  21. Odsbu I, Klungsøyr HK, Fossum S, Skarstad K (2005)
    Specific N-terminal interactions of the Escherichia coli SeqA protein are required to form multimers that restrain negative supercoils and form foci
    Genes Cells, 10 (11), 1039-49
    DOI 10.1111/j.1365-2443.2005.00898.x, PubMed 16236133
  22. Samari HR, Møller MT, Holden L, Asmyhr T, Seglen PO (2005)
    Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins
    Biochem J, 386 (Pt 2), 237-44
    DOI 10.1042/BJ20040609, PubMed 15461583
  23. Sandvig K, van Deurs B (2005)
    Delivery into cells: lessons learned from plant and bacterial toxins
    Gene Ther, 12 (11), 865-72
    DOI 10.1038/sj.gt.3302525, PubMed 15815697
  24. Sioud M, Wälchli S (2005)
    Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs
    Methods Mol Biol, 309, 83-91
    DOI 10.1385/1-59259-935-4:083, PubMed 15990399
  25. Slagsvold T, Aasland R, Hirano S, Bache KG, Raiborg C, Trambaiolo D, Wakatsuki S, Stenmark H (2005)
    Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain
    J Biol Chem, 280 (20), 19600-6
    DOI 10.1074/jbc.M501510200, PubMed 15755741
  26. Sneve ML, Øverbye A, Fengsrud M, Seglen PO (2005)
    Comigration of two autophagosome-associated dehydrogenases on two-dimensional polyacrylamide gels
    Autophagy, 1 (3), 157-62
    DOI 10.4161/auto.1.3.2037, PubMed 16874067
  27. Spilsberg B, Hanada K, Sandvig K (2005)
    Diphtheria toxin translocation across cellular membranes is regulated by sphingolipids
    Biochem Biophys Res Commun, 329 (2), 465-73
    DOI 10.1016/j.bbrc.2005.02.005, PubMed 15737610
  28. Spilsberg B, Sandvig K, Wälchli S (2005)
    Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria
    Toxicon, 46 (8), 900-6
    DOI 10.1016/j.toxicon.2005.08.015, PubMed 16260019
  29. Stige LC, Slagsvold T, Vollestad LA (2005)
    Individual fluctuating asymmetry in pied flycatchers (Ficedula hypoleuca) persists across moults, but is not heritable and not related to fitness
    Evol. Ecol. Res., 7 (3), 381-406
  30. Torgersen ML, Lauvrak SU, Sandvig K (2005)
    The A-subunit of surface-bound Shiga toxin stimulates clathrin-dependent uptake of the toxin
    FEBS J, 272 (16), 4103-13
    DOI 10.1111/j.1742-4658.2005.04835.x, PubMed 16098193
  31. Voigt B, Timmers AC, Samaj J, Hlavacka A, Ueda T, Preuss M, Nielsen E, Mathur J, Emans N, Stenmark H, Nakano A, Baluska F, Menzel D (2005)
    Actin-based motility of endosomes is linked to the polar tip growth of root hairs
    Eur J Cell Biol, 84 (6), 609-21
    DOI 10.1016/j.ejcb.2004.12.029, PubMed 16032929
  32. Wesche J, Małecki J, Wiedłocha A, Ehsani M, Marcinkowska E, Nilsen T, Olsnes S (2005)
    Two nuclear localization signals required for transport from the cytosol to the nucleus of externally added FGF-1 translocated into cells
    Biochemistry, 44 (16), 6071-80
    DOI 10.1021/bi047403m, PubMed 15835896
  33. Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2005)
    Highly stable mutants of human fibroblast growth factor-1 exhibit prolonged biological action
    J Mol Biol, 352 (4), 860-75
    DOI 10.1016/j.jmb.2005.07.066, PubMed 16126225

Publications 2004

  1. Bach T, Skarstad K (2004)
    Re-replication from non-sequesterable origins generates three-nucleoid cells which divide asymmetrically
    Mol Microbiol, 51 (6), 1589-600
    DOI 10.1111/j.1365-2958.2003.03943.x, PubMed 15009887
  2. Bache KG, Slagsvold T, Cabezas A, Rosendal KR, Raiborg C, Stenmark H (2004)
    The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
    Mol Biol Cell, 15 (9), 4337-46
    DOI 10.1091/mbc.e04-03-0250, PubMed 15240819
  3. Bache KG, Slagsvold T, Stenmark H (2004)
    Defective downregulation of receptor tyrosine kinases in cancer
    EMBO J, 23 (14), 2707-12
    DOI 10.1038/sj.emboj.7600292, PubMed 15229652
  4. Birkeland HC, Stenmark H (2004)
    Protein targeting to endosomes and phagosomes via FYVE and PX domains
    Curr Top Microbiol Immunol, 282, 89-115
    DOI 10.1007/978-3-642-18805-3_4, PubMed 14594215
  5. Engelhardt M, Pfadenhauer K, Zentner J, Grimmer S, Wachenfeld-Wahl C, Heidenreich P, Loeprecht H, Wölfle KD (2004)
    [Impaired cerebral autoregulation in asymptomatic patients with carotid artery stenosis: comparison of acetazolamide-SPECT and transcranial CO(2)-dopplersonography]
    Zentralbl Chir, 129 (3), 178-82
    DOI 10.1055/s-2004-822798, PubMed 15237321
  6. Gruenberg J, Stenmark H (2004)
    The biogenesis of multivesicular endosomes
    Nat Rev Mol Cell Biol, 5 (4), 317-23
    DOI 10.1038/nrm1360, PubMed 15071556
  7. Hansen BT, Slagsvold T (2004)
    Early learning affects social dominance: interspecifically cross-fostered tits become subdominant
    Behav. Ecol., 15 (2), 262-268
    DOI 10.1093/beheco/arh010
  8. Jacobs CM, Boldingh KA, Slagsvold HH, Thoresen GH, Paulsen RE (2004)
    ERK2 prohibits apoptosis-induced subcellular translocation of orphan nuclear receptor NGFI-B/TR3
    J Biol Chem, 279 (48), 50097-101
    DOI 10.1074/jbc.M409145200, PubMed 15448159
  9. Johnson HM, Subramaniam PS, Olsnes S, Jans DA (2004)
    Trafficking and signaling pathways of nuclear localizing protein ligands and their receptors
    Bioessays, 26 (9), 993-1004
    DOI 10.1002/bies.20086, PubMed 15351969
  10. Klungsøyr HK, Skarstad K (2004)
    Positive supercoiling is generated in the presence of Escherichia coli SeqA protein
    Mol Microbiol, 54 (1), 123-31
    DOI 10.1111/j.1365-2958.2004.04239.x, PubMed 15458410
  11. Kourmanova AG, Soudarkina OJ, Olsnes S, Kozlov JV (2004)
    Cloning and characterization of the genes encoding toxic lectins in mistletoe (Viscum album L)
    Eur J Biochem, 271 (12), 2350-60
    DOI 10.1111/j.1432-1033.2004.04153.x, PubMed 15182350
  12. Kowanetz K, Crosetto N, Haglund K, Schmidt MHH, Heldin CH, Dikic I (2004)
    Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases
    J Biol Chem, 279 (31), 32786-95
    DOI 10.1074/jbc.M403759200, PubMed 15159412
  13. Lauvrak SU, Torgersen ML, Sandvig K (2004)
    Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin
    J Cell Sci, 117 (Pt 11), 2321-31
    DOI 10.1242/jcs.01081, PubMed 15126632
  14. Loog M, Oskolkov N, O'Farrell F, Ek P, Järv J (2004)
    Comparison of cAMP-dependent protein kinase substrate specificity in reaction with proteins and synthetic peptides
    Biochim Biophys Acta, 1747 (2), 261-6
    DOI 10.1016/j.bbapap.2004.11.016, PubMed 15698961
  15. Masson V, de la Ballina LR, Munaut C, Wielockx B, Jost M, Maillard C, Blacher S, Bajou K, Itoh T, Itohara S, Werb Z, Libert C, Foidart JM, Noël A (2004)
    Contribution of host MMP-2 and MMP-9 to promote tumor vascularization and invasion of malignant keratinocytes
    FASEB J, 19 (2), 234-6
    DOI 10.1096/fj.04-2140fje, PubMed 15550552
  16. Molina F, Skarstad K (2004)
    Replication fork and SeqA focus distributions in Escherichia coli suggest a replication hyperstructure dependent on nucleotide metabolism
    Mol Microbiol, 52 (6), 1597-612
    DOI 10.1111/j.1365-2958.2004.04097.x, PubMed 15186411
  17. Møller MT, Samari HR, Seglen PO (2004)
    Toxin-induced tail phosphorylation of hepatocellular S6 kinase: evidence for a dual involvement of the AMP-activated protein kinase in S6 kinase regulation
    Toxicol Sci, 82 (2), 628-37
    DOI 10.1093/toxsci/kfh273, PubMed 15342961
  18. Nilssen EA, Synnes M, Tvegård T, Vebø H, Boye E, Grallert B (2004)
    Germinating fission yeast spores delay in G1 in response to UV irradiation
    BMC Cell Biol, 5 (1), 40
    DOI 10.1186/1471-2121-5-40, PubMed 15498101
  19. Olsnes S (2004)
    The history of ricin, abrin and related toxins
    Toxicon, 44 (4), 361-70
    DOI 10.1016/j.toxicon.2004.05.003, PubMed 15302520
  20. Ramírez M, Vinagre A, Ambrona J, Molina F, Maqueda M, Rebollo JE (2004)
    Genetic instability of heterozygous, hybrid, natural wine yeasts
    Appl Environ Microbiol, 70 (8), 4686-91
    DOI 10.1128/AEM.70.8.4686-4691.2004, PubMed 15294803
  21. Rusten TE, Lindmo K, Juhász G, Sass M, Seglen PO, Brech A, Stenmark H (2004)
    Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
    Dev Cell, 7 (2), 179-92
    DOI 10.1016/j.devcel.2004.07.005, PubMed 15296715
  22. Sandvig K, Spilsberg B, Lauvrak SU, Torgersen ML, Iversen TG, van Deurs B (2004)
    Pathways followed by protein toxins into cells
    Int J Med Microbiol, 293 (7-8), 483-90
    DOI 10.1078/1438-4221-00294, PubMed 15149022
  23. Sharma M, Pampinella F, Nemes C, Benharouga M, So J, Du K, Bache KG, Papsin B, Zerangue N, Stenmark H, Lukacs GL (2004)
    Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes
    J Cell Biol, 164 (6), 923-33
    DOI 10.1083/jcb.200312018, PubMed 15007060
  24. Simonsen A, Birkeland HC, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A, Stenmark H (2004)
    Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
    J Cell Sci, 117 (Pt 18), 4239-51
    DOI 10.1242/jcs.01287, PubMed 15292400
  25. Slagsvold T, Stenmark H (2004)
    The structure of an endosomal protein sorter
    Dev Cell, 7 (4), 457-8
    DOI 10.1016/j.devcel.2004.09.007, PubMed 15469831
  26. Stang E, Blystad FD, Kazazic M, Bertelsen V, Brodahl T, Raiborg C, Stenmark H, Madshus IH (2004)
    Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits
    Mol Biol Cell, 15 (8), 3591-604
    DOI 10.1091/mbc.e04-01-0041, PubMed 15194809
  27. Sørensen V, Brech A, Khnykin D, Kolpakova E, Citores L, Olsnes S (2004)
    Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus
    J Cell Sci, 117 (Pt 9), 1807-19
    DOI 10.1242/jcs.01047, PubMed 15075241
  28. Vieira OV, Harrison RE, Scott CC, Stenmark H, Alexander D, Liu J, Gruenberg J, Schreiber AD, Grinstein S (2004)
    Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria
    Mol Cell Biol, 24 (10), 4593-604
    DOI 10.1128/MCB.24.10.4593-4604.2004, PubMed 15121875
  29. Wiedłocha A, Nilsen T, Wesche J, Sørensen V, Małecki J, Marcinkowska E, Olsnes S (2004)
    Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1
    Mol Biol Cell, 16 (2), 794-810
    DOI 10.1091/mbc.e04-05-0389, PubMed 15574884
  30. Wiedłocha A, Sørensen V (2004)
    Signaling, internalization, and intracellular activity of fibroblast growth factor
    Curr Top Microbiol Immunol, 286, 45-79
    DOI 10.1007/978-3-540-69494-6_3, PubMed 15645710
  31. Zakrzewska M, Krowarsch D, Wiedlocha A, Otlewski J (2004)
    Design of fully active FGF-1 variants with increased stability
    Protein Eng Des Sel, 17 (8), 603-11
    DOI 10.1093/protein/gzh076, PubMed 15469994

Publications 2003

  1. Bach T, Krekling MA, Skarstad K (2003)
    Excess SeqA prolongs sequestration of oriC and delays nucleoid segregation and cell division
    EMBO J, 22 (2), 315-23
    DOI 10.1093/emboj/cdg020, PubMed 12514137
  2. Bache KG, Brech A, Mehlum A, Stenmark H (2003)
    Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
    J Cell Biol, 162 (3), 435-42
    DOI 10.1083/jcb.200302131, PubMed 12900395
  3. Bache KG, Raiborg C, Mehlum A, Stenmark H (2003)
    STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
    J Biol Chem, 278 (14), 12513-21
    DOI 10.1074/jbc.M210843200, PubMed 12551915
  4. Boye E, Nordström K (2003)
    Coupling the cell cycle to cell growth
    EMBO Rep, 4 (8), 757-60
    DOI 10.1038/sj.embor.embor895, PubMed 12897798
  5. Bråthe A, Gundersen LL, Nissen-Meyer J, Rise F, Spilsberg B (2003)
    Cytotoxic activity of 6-alkynyl- and 6-alkenylpurines
    Bioorg Med Chem Lett, 13 (5), 877-80
    DOI 10.1016/s0960-894x(03)00011-8, PubMed 12617912
  6. Camara JE, Skarstad K, Crooke E (2003)
    Controlled initiation of chromosomal replication in Escherichia coli requires functional Hda protein
    J Bacteriol, 185 (10), 3244-8
    DOI 10.1128/JB.185.10.3244-3248.2003, PubMed 12730188
  7. Duś D, Krawczenko A, Załecki P, Paprocka M, Wiedłocha A, Goupille C, Kieda C (2003)
    IL-7 receptor is present on human microvascular endothelial cells
    Immunol Lett, 86 (2), 163-8
    DOI 10.1016/s0165-2478(03)00018-x, PubMed 12644318
  8. Fossum S, Søreide S, Skarstad K (2003)
    Lack of SeqA focus formation, specific DNA binding and proper protein multimerization in the Escherichia coli sequestration mutant seqA2
    Mol Microbiol, 47 (3), 619-32
    DOI 10.1046/j.1365-2958.2003.t01-1-03329.x, PubMed 12535065
  9. Furre T, Furre EI, Koritzinsky M, Amellem Ø, Pettersen EO (2003)
    Lack of inverse dose-rate effect and binding of the retinoblastoma gene product in the nucleus of human cancer T-47D cells arrested in G2 by ionizing radiation
    Int J Radiat Biol, 79 (6), 413-22
    DOI 10.1080/0955300031000140784, PubMed 12963543
  10. Gillooly DJ, Raiborg C, Stenmark H (2003)
    Phosphatidylinositol 3-phosphate is found in microdomains of early endosomes
    Histochem Cell Biol, 120 (6), 445-53
    DOI 10.1007/s00418-003-0591-7, PubMed 14618335
  11. González-Gaitán M, Stenmark H (2003)
    Endocytosis and signaling: a relationship under development
    Cell, 115 (5), 513-21
    DOI 10.1016/s0092-8674(03)00932-2, PubMed 14651844
  12. Gregers TF, Nordeng TW, Birkeland HC, Sandlie I, Bakke O (2003)
    The cytoplasmic tail of invariant chain modulates antigen processing and presentation
    Eur J Immunol, 33 (2), 277-86
    DOI 10.1002/immu.200310001, PubMed 12548558
  13. Holme HK, Lindmo K, Kristiansen A, Smidsrod O (2003)
    Thermal depolymerization of alginate in the solid state
    Carbohydr. Polym., 54 (4), 431-438
    DOI 10.1016/S0144-8617(03)00134-6
  14. Iversen TG, Skretting G, van Deurs B, Sandvig K (2003)
    Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA
    Proc Natl Acad Sci U S A, 100 (9), 5175-80
    DOI 10.1073/pnas.0534231100, PubMed 12682302
  15. Kang S, Han JS, Park JH, Skarstad K, Hwang DS (2003)
    SeqA protein stimulates the relaxing and decatenating activities of topoisomerase IV
    J Biol Chem, 278 (49), 48779-85
    DOI 10.1074/jbc.M308843200, PubMed 14512422
  16. Kolpakova E, Rusten TE, Olsnes S (2003)
    Characterization and tissue expression of acidic fibroblast growth factor binding protein homologue in Drosophila melanogaster
    Gene, 310, 185-91
    DOI 10.1016/s0378-1119(03)00550-x, PubMed 12801646
  17. Kowanetz K, Szymkiewicz I, Haglund K, Kowanetz M, Husnjak K, Taylor JD, Soubeyran P, Engstrom U, Ladbury JE, Dikic I (2003)
    Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors
    J Biol Chem, 278 (41), 39735-46
    DOI 10.1074/jbc.M304541200, PubMed 12874286
  18. Llorente A, Lauvrak SU, van Deurs B, Sandvig K (2003)
    Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP)
    J Biol Chem, 278 (37), 35850-5
    DOI 10.1074/jbc.M303425200, PubMed 12847103
  19. Małecki J, Wesche J, Skjerpen CS, Wiedłocha A, Olsnes S (2003)
    Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism
    Mol Biol Cell, 15 (2), 801-14
    DOI 10.1091/mbc.e03-08-0589, PubMed 14657241
  20. Marchese A, Raiborg C, Santini F, Keen JH, Stenmark H, Benovic JL (2003)
    The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
    Dev Cell, 5 (5), 709-22
    DOI 10.1016/s1534-5807(03)00321-6, PubMed 14602072
  21. Marcinkowska E, Wiedlocha A (2003)
    Phosphatidylinositol-3 kinase-dependent activation of Akt does not correlate with either high mitogenicity or cell migration induced by FGF-1
    Anticancer Res, 23 (5A), 4071-7
    PubMed 14666721
  22. Miller C, Ingmer H, Thomsen LE, Skarstad K, Cohen SN (2003)
    DpiA binding to the replication origin of Escherichia coli plasmids and chromosomes destabilizes plasmid inheritance and induces the bacterial SOS response
    J Bacteriol, 185 (20), 6025-31
    DOI 10.1128/JB.185.20.6025-6031.2003, PubMed 14526013
  23. Morigen, Løbner-Olesen A, Skarstad K (2003)
    Titration of the Escherichia coli DnaA protein to excess datA sites causes destabilization of replication forks, delayed replication initiation and delayed cell division
    Mol Microbiol, 50 (1), 349-62
    DOI 10.1046/j.1365-2958.2003.03695.x, PubMed 14507385
  24. Mousavi SA, Brech A, Berg T, Kjeken R (2003)
    Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes
    Biochem J, 372 (Pt 3), 861-9
    DOI 10.1042/BJ20021136, PubMed 12646047
  25. Møller MT, Samari HR, Fengsrud M, Strømhaug PE, øStvold AC, Seglen PO (2003)
    Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes
    Biochem J, 373 (Pt 2), 505-13
    DOI 10.1042/BJ20030502, PubMed 12697024
  26. Nilsen T, Slagsvold T, Skjerpen CS, Brech A, Stenmark H, Olsnes S (2003)
    Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
    J Biol Chem, 279 (6), 4794-801
    DOI 10.1074/jbc.M309653200, PubMed 14604990
  27. Nilssen EA, Synnes M, Kleckner N, Grallert B, Boye E (2003)
    Intra-G1 arrest in response to UV irradiation in fission yeast
    Proc Natl Acad Sci U S A, 100 (19), 10758-63
    DOI 10.1073/pnas.1833769100, PubMed 12960401
  28. Olsnes S, Klingenberg O, Wiedłocha A (2003)
    Transport of exogenous growth factors and cytokines to the cytosol and to the nucleus
    Physiol Rev, 83 (1), 163-82
    DOI 10.1152/physrev.00021.2002, PubMed 12506129
  29. Petiot A, Faure J, Stenmark H, Gruenberg J (2003)
    PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
    J Cell Biol, 162 (6), 971-9
    DOI 10.1083/jcb.200303018, PubMed 12975344
  30. Raiborg C, Rusten TE, Stenmark H (2003)
    Protein sorting into multivesicular endosomes
    Curr Opin Cell Biol, 15 (4), 446-55
    DOI 10.1016/s0955-0674(03)00080-2, PubMed 12892785
  31. Rojo MA, Citores L, Jiménez P, Ferreras JM, Arias FJ, Méndez E, Girbés T (2003)
    Isolation and characterization of a new d-galactose-binding lectin from Sambucus racemosa L
    Protein Pept Lett, 10 (3), 287-93
    DOI 10.2174/0929866033478979, PubMed 12871149
  32. Sandvig K, van Deurs B (2003)
    Cholera toxin internalization and intoxication - Reply
    J. Cell Sci., 116 (3), 432-433
    DOI 10.1242/jcs.00200
  33. Schedlich LJ, Nilsen T, John AP, Jans DA, Baxter RC (2003)
    Phosphorylation of insulin-like growth factor binding protein-3 by deoxyribonucleic acid-dependent protein kinase reduces ligand binding and enhances nuclear accumulation
    Endocrinology, 144 (5), 1984-93
    DOI 10.1210/en.2002-220798, PubMed 12697706
  34. Skarstad K, Boye E, Fanning E (2003)
    Circles in the sand
    EMBO Rep, 4 (7), 661-5
    DOI 10.1038/sj.embor.embor888, PubMed 12835752
  35. Skarstad K, Løbner-Olesen A (2003)
    Stable co-existence of separate replicons in Escherichia coli is dependent on once-per-cell-cycle initiation
    EMBO J, 22 (1), 140-50
    DOI 10.1093/emboj/cdg003, PubMed 12505992
  36. Slominska M, Wahl A, Wegrzyn G, Skarstad K (2003)
    Degradation of mutant initiator protein DnaA204 by proteases ClpP, ClpQ and Lon is prevented when DNA is SeqA-free
    Biochem J, 370 (Pt 3), 867-71
    DOI 10.1042/BJ20021161, PubMed 12479794
  37. Spilsberg B, Van Meer G, Sandvig K (2003)
    Role of lipids in the retrograde pathway of ricin intoxication
    Traffic, 4 (8), 544-52
    DOI 10.1034/j.1600-0854.2003.00111.x, PubMed 12839497
  38. Storen T, Simonsen A, Royset AK, Lokberg OJ, Svaasand LO, Lindmo T (2003)
    Time resolved spectroscopic optical coherence tomography for diffusion measurements
    P SOC PHOTO-OPT INS, 4956, 197-204
    DOI 10.1117/12.477645
  39. van Deurs B, Roepstorff K, Hommelgaard AM, Sandvig K (2003)
    Caveolae: anchored, multifunctional platforms in the lipid ocean
    Trends Cell Biol, 13 (2), 92-100
    DOI 10.1016/s0962-8924(02)00039-9, PubMed 12559760
  40. Ying M, Grimmer S, Iversen TG, Van Deurs B, Sandvig K (2003)
    Cholesterol loading induces a block in the exit of VSVG from the TGN
    Traffic, 4 (11), 772-84
    DOI 10.1034/j.1600-0854.2003.00134.x, PubMed 14617359

Publications 2002

  1. Andresen G, Gundersen LL, Nissen-Meyer J, Rise F, Spilsberg B (2002)
    Cytotoxic and antibacterial activity of 2-oxopurine derivatives
    Bioorg Med Chem Lett, 12 (4), 567-9
    DOI 10.1016/s0960-894x(01)00803-4, PubMed 11844673
  2. Bache KG, Raiborg C, Mehlum A, Madshus IH, Stenmark H (2002)
    Phosphorylation of Hrs downstream of the epidermal growth factor receptor
    Eur J Biochem, 269 (16), 3881-7
    DOI 10.1046/j.1432-1033.2002.03046.x, PubMed 12180964
  3. Birkeli KA, Llorente A, Torgersen ML, Keryer G, Taskén K, Sandvig K (2002)
    Endosome-to-Golgi transport is regulated by protein kinase A type II alpha
    J Biol Chem, 278 (3), 1991-7
    DOI 10.1074/jbc.M209982200, PubMed 12419802
  4. Braathen R, Sorensen V, Brandtzaeg P, Sandlie I, Johansen FE (2002)
    The carboxyl-terminal domains of IgA and IgM direct isotype-specific polymerization and interaction with the polymeric immunoglobulin receptor
    J Biol Chem, 277 (45), 42755-62
    DOI 10.1074/jbc.M205502200, PubMed 12213814
  5. Grimmer S, van Deurs B, Sandvig K (2002)
    Membrane ruffling and macropinocytosis in A431 cells require cholesterol
    J Cell Sci, 115 (Pt 14), 2953-62
    DOI 10.1242/jcs.115.14.2953, PubMed 12082155
  6. Gundersen LL, Nissen-Meyer J, Spilsberg B (2002)
    Synthesis and antimycobacterial activity of 6-arylpurines: the requirements for the N-9 substituent in active antimycobacterial purines
    J Med Chem, 45 (6), 1383-6
    DOI 10.1021/jm0110284, PubMed 11882008
  7. Kauppi M, Simonsen A, Bremnes B, Vieira A, Callaghan J, Stenmark H, Olkkonen VM (2002)
    The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
    J Cell Sci, 115 (Pt 5), 899-911
    DOI 10.1242/jcs.115.5.899, PubMed 11870209
  8. Lagaudrière-Gesbert C, Newmyer SL, Gregers TF, Bakke O, Ploegh HL (2002)
    Uncoating ATPase Hsc70 is recruited by invariant chain and controls the size of endocytic compartments
    Proc Natl Acad Sci U S A, 99 (3), 1515-20
    DOI 10.1073/pnas.042688099, PubMed 11818572
  9. Larsen AK, Møller MT, Blankson H, Samari HR, Holden L, Seglen PO (2002)
    Naringin-sensitive phosphorylation of plectin, a cytoskeletal cross-linking protein, in isolated rat hepatocytes
    J Biol Chem, 277 (38), 34826-35
    DOI 10.1074/jbc.M205028200, PubMed 12095991
  10. Lauvrak SU, Llorente A, Iversen TG, Sandvig K (2002)
    Selective regulation of the Rab9-independent transport of ricin to the Golgi apparatus by calcium
    J Cell Sci, 115 (Pt 17), 3449-56
    DOI 10.1242/jcs.115.17.3449, PubMed 12154075
  11. Luk'ianov EV, Viedlokha A, Kuianskaia DV, Olsnes S, Kozlov IuV (2002)
    [A short form of the heparin-binding EGF-like growth factor with a changed EGF domain]
    Mol Biol (Mosk), 36 (1), 76-83
    PubMed 11862716
  12. Luk'yanov EV, Viedlokha A, Kuyavskaya DV, Olsnes S, Kozlov YV (2002)
    A short form of the heparin-binding EGF-like growth factor with a changed EGF domain
    Mol. Biol., 36 (1), 58-64
    DOI 10.1023/A:1014246423243
  13. Małecki J, Wiedłocha A, Wesche J, Olsnes S (2002)
    Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1
    EMBO J, 21 (17), 4480-90
    DOI 10.1093/emboj/cdf472, PubMed 12198150
  14. Marcinkowska E, Wiedłocha A (2002)
    Steroid signal transduction activated at the cell membrane: from plants to animals
    Acta Biochim Pol, 49 (3), 735-45
    PubMed 12422243
  15. Murray JT, Panaretou C, Stenmark H, Miaczynska M, Backer JM (2002)
    Role of Rab5 in the recruitment of hVps34/p150 to the early endosome
    Traffic, 3 (6), 416-27
    DOI 10.1034/j.1600-0854.2002.30605.x, PubMed 12010460
  16. Nordeng TW, Gregers TF, Kongsvik TL, Méresse S, Gorvel JP, Jourdan F, Motta A, Bakke O (2002)
    The cytoplasmic tail of invariant chain regulates endosome fusion and morphology
    Mol Biol Cell, 13 (6), 1846-56
    DOI 10.1091/mbc.01-10-0478, PubMed 12058053
  17. Panopoulou E, Gillooly DJ, Wrana JL, Zerial M, Stenmark H, Murphy C, Fotsis T (2002)
    Early endosomal regulation of Smad-dependent signaling in endothelial cells
    J Biol Chem, 277 (20), 18046-52
    DOI 10.1074/jbc.M107983200, PubMed 11877415
  18. Raiborg C, Bache KG, Gillooly DJ, Madshus IH, Stang E, Stenmark H (2002)
    Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
    Nat Cell Biol, 4 (5), 394-8
    DOI 10.1038/ncb791, PubMed 11988743
  19. Raiborg C, Stenmark H (2002)
    Hrs and endocytic sorting of ubiquitinated membrane proteins
    Cell Struct Funct, 27 (6), 403-8
    DOI 10.1247/csf.27.403, PubMed 12576633
  20. Roepstorff K, Thomsen P, Sandvig K, van Deurs B (2002)
    Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding
    J Biol Chem, 277 (21), 18954-60
    DOI 10.1074/jbc.M201422200, PubMed 11886870
  21. Sandvig K, van Deurs B (2002)
    Membrane traffic exploited by protein toxins
    Annu Rev Cell Dev Biol, 18, 1-24
    DOI 10.1146/annurev.cellbio.18.011502.142107, PubMed 12142266
  22. Sandvig K, van Deurs B (2002)
    Transport of protein toxins into cells: pathways used by ricin, cholera toxin and Shiga toxin
    FEBS Lett, 529 (1), 49-53
    DOI 10.1016/s0014-5793(02)03182-4, PubMed 12354612
  23. Shimokawa N, Okada J, Haglund K, Dikic I, Koibuchi N, Miura M (2002)
    Past-A, a novel proton-associated sugar transporter, regulates glucose homeostasis in the brain
    J Neurosci, 22 (21), 9160-5
    DOI 10.1523/JNEUROSCI.22-21-09160.2002, PubMed 12417639
  24. Skjerpen CS, Nilsen T, Wesche J, Olsnes S (2002)
    Binding of FGF-1 variants to protein kinase CK2 correlates with mitogenicity
    EMBO J, 21 (15), 4058-69
    DOI 10.1093/emboj/cdf402, PubMed 12145206
  25. Skjerpen CS, Wesche J, Olsnes S (2002)
    Identification of ribosome-binding protein p34 as an intracellular protein that binds acidic fibroblast growth factor
    J Biol Chem, 277 (26), 23864-71
    DOI 10.1074/jbc.M112193200, PubMed 11964394
  26. Stenmark H, Aasland R, Driscoll PC (2002)
    The phosphatidylinositol 3-phosphate-binding FYVE finger
    FEBS Lett, 513 (1), 77-84
    DOI 10.1016/s0014-5793(01)03308-7, PubMed 11911884
  27. Synnes M, Nilssen EA, Boye E, Grallert B (2002)
    A novel chk1-dependent G1/M checkpoint in fission yeast
    J Cell Sci, 115 (Pt 18), 3609-18
    DOI 10.1242/jcs.00004, PubMed 12186947
  28. Tse SM, Furuya W, Gold E, Schreiber AD, Sandvig K, Inman RD, Grinstein S (2002)
    Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis
    J Biol Chem, 278 (5), 3331-8
    DOI 10.1074/jbc.M207966200, PubMed 12424246
  29. Wabakken T, Hauge H, Finne EF, Wiedlocha A, Aasheim H (2002)
    Expression of human protein tyrosine phosphatase epsilon in leucocytes: a potential ERK pathway-regulating phosphatase
    Scand J Immunol, 56 (2), 195-203
    DOI 10.1046/j.1365-3083.2002.01126.x, PubMed 12121439
  30. Wesche J (2002)
    Retrograde transport of ricin
    Int J Med Microbiol, 291 (6-7), 517-21
    DOI 10.1078/1438-4221-00161, PubMed 11890552

Publications 2001

  1. Berven G, Saetre F, Halvorsen K, Seglen PO (2001)
    Effects of the diarrhetic shellfish toxin, okadaic acid, on cytoskeletal elements, viability and functionality of rat liver and intestinal cells
    Toxicon, 39 (2-3), 349-62
    DOI 10.1016/s0041-0101(00)00137-9, PubMed 10978754
  2. Boye E, Blinkova A, Walker JR (2001)
    Defective initiation in an Escherichia coli dnaA(Cs,Sx) mutant
    Biochimie, 83 (1), 25-32
    DOI 10.1016/s0300-9084(00)01230-x, PubMed 11254971
  3. Citores L, Khnykin D, Sørensen V, Wesche J, Klingenberg O, Wiedłocha A, Olsnes S (2001)
    Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain
    J Cell Sci, 114 (Pt 9), 1677-89
    DOI 10.1242/jcs.114.9.1677, PubMed 11398757
  4. Falnes PØ, Wesche J, Olsnes S (2001)
    Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment
    Biochemistry, 40 (14), 4349-58
    DOI 10.1021/bi002443l, PubMed 11284691
  5. Garred Ø, Rodal SK, van Deurs B, Sandvig K (2001)
    Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase
    Traffic, 2 (1), 26-36
    DOI 10.1034/j.1600-0854.2001.020105.x, PubMed 11208166
  6. Gillooly DJ, Simonsen A, Stenmark H (2001)
    Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
    Biochem J, 355 (Pt 2), 249-58
    DOI 10.1042/0264-6021:3550249, PubMed 11284710
  7. Gillooly DJ, Simonsen A, Stenmark H (2001)
    Phosphoinositides and phagocytosis
    J Cell Biol, 155 (1), 15-7
    DOI 10.1083/jcb.200109001, PubMed 11581282
  8. Gillooly DJ, Stenmark H (2001)
    Cell biology. A lipid oils the endocytosis machine
    Science, 291 (5506), 993-4
    DOI 10.1126/science.291.5506.993, PubMed 11232585
  9. Iversen TG, Skretting G, Llorente A, Nicoziani P, van Deurs B, Sandvig K (2001)
    Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPases
    Mol Biol Cell, 12 (7), 2099-107
    DOI 10.1091/mbc.12.7.2099, PubMed 11452006
  10. Kim DH, Eu YJ, Yoo CM, Kim YW, Pih KT, Jin JB, Kim SJ, Stenmark H, Hwang I (2001)
    Trafficking of phosphatidylinositol 3-phosphate from the trans-Golgi network to the lumen of the central vacuole in plant cells
    Plant Cell, 13 (2), 287-301
    DOI 10.1105/tpc.13.2.287, PubMed 11226186
  11. Kim J, Kamada Y, Stromhaug PE, Guan J, Hefner-Gravink A, Baba M, Scott SV, Ohsumi Y, Dunn WA, Klionsky DJ (2001)
    Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole
    J Cell Biol, 153 (2), 381-96
    DOI 10.1083/jcb.153.2.381, PubMed 11309418
  12. Kjeken R, Mousavi SA, Brech A, Gjøen T, Berg T (2001)
    Fluid phase endocytosis of [125I]iodixanol in rat liver parenchymal, endothelial and Kupffer cells
    Cell Tissue Res, 304 (2), 221-30
    DOI 10.1007/s004410100348, PubMed 11396716
  13. Kjeken R, Mousavi SA, Brech A, Griffiths G, Berg T (2001)
    Wortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cells
    Biochem J, 357 (Pt 2), 497-503
    DOI 10.1042/0264-6021:3570497, PubMed 11439100
  14. Koritzinsky M, Wouters BG, Amellem O, Pettersen EO (2001)
    Cell cycle progression and radiation survival following prolonged hypoxia and re-oxygenation
    Int J Radiat Biol, 77 (3), 319-28
    DOI 10.1080/09553000010019278, PubMed 11258846
  15. Llorente A, Prydz K, Sprangers M, Skretting G, Kolset SO, Sandvig K (2001)
    Proteoglycan synthesis is increased in cells with impaired clathrin-dependent endocytosis
    J Cell Sci, 114 (Pt 2), 335-43
    DOI 10.1242/jcs.114.2.335, PubMed 11148135
  16. Loukianov EV, Wiedlocha A, Olsnes S, Kozlov YV (2001)
    Two farms of the heparin-binding EGF-like growth factor precursor, a receptor for diphtheria toxin
    Mol. Biol., 35 (1), 122-129
    DOI 10.1023/A:1004819321876
  17. Luk'ianov EV, Viedlokha A, Olsnes S, Kozlov IuV (2001)
    [Two forms of precursors of a heparin-binding EGF-like growth factor-diphtheria toxin receptor]
    Mol Biol (Mosk), 35 (1), 136-45
    PubMed 11234372
  18. Lunde E, Rasmussen IB, Eidem JK, Gregers TF, Western KH, Bogen B, Sandlie I (2001)
    'Troy-bodies': antibodies as vector proteins for T cell epitopes
    Biomol Eng, 18 (3), 109-16
    DOI 10.1016/s1389-0344(01)00091-0, PubMed 11566602
  19. Marcinkowska E, Chrobak A, Wiedłocha A (2001)
    Evading apoptosis by calcitriol-differentiated human leukemic HL-60 cells is not mediated by changes in CD95 receptor system but by increased sensitivity of these cells to insulin
    Exp Cell Res, 270 (1), 119-27
    DOI 10.1006/excr.2001.5335, PubMed 11597134
  20. Morigen, Boye E, Skarstad K, Løbner-Olesen A (2001)
    Regulation of chromosomal replication by DnaA protein availability in Escherichia coli: effects of the datA region
    Biochim Biophys Acta, 1521 (1-3), 73-80
    DOI 10.1016/s0167-4781(01)00292-5, PubMed 11690638
  21. Mousavi SA, Kjeken R, Berg TO, Seglen PO, Berg T, Brech A (2001)
    Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy
    Biochim Biophys Acta, 1510 (1-2), 243-57
    DOI 10.1016/s0005-2736(00)00354-0, PubMed 11342162
  22. Olsnes S, Kozlov JV (2001)
    Ricin
    Toxicon, 39 (11), 1723-8
    DOI 10.1016/s0041-0101(01)00158-1, PubMed 11595634
  23. Olsnes S, Wesche J (2001)
    Microbiology. Fighting anthrax with a mutant toxin
    Science, 292 (5517), 647-8
    DOI 10.1126/science.1060857, PubMed 11330322
  24. Pattni K, Jepson M, Stenmark H, Banting G (2001)
    A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells
    Curr Biol, 11 (20), 1636-42
    DOI 10.1016/s0960-9822(01)00486-9, PubMed 11676927
  25. Raiborg C, Bache KG, Mehlum A, Stang E, Stenmark H (2001)
    Hrs recruits clathrin to early endosomes
    EMBO J, 20 (17), 5008-21
    DOI 10.1093/emboj/20.17.5008, PubMed 11532964
  26. Raiborg C, Bache KG, Mehlum A, Stenmark H (2001)
    Function of Hrs in endocytic trafficking and signalling
    Biochem Soc Trans, 29 (Pt 4), 472-5
    DOI 10.1042/bst0290472, PubMed 11498011
  27. Raiborg C, Bremnes B, Mehlum A, Gillooly DJ, D'Arrigo A, Stang E, Stenmark H (2001)
    FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes
    J Cell Sci, 114 (Pt 12), 2255-63
    DOI 10.1242/jcs.114.12.2255, PubMed 11493665
  28. Sandvig K (2001)
    Shiga toxins
    Toxicon, 39 (11), 1629-35
    DOI 10.1016/s0041-0101(01)00150-7, PubMed 11595626
  29. Sandvig K, Grimmer S, Lauvrak SU, Torgersen ML, Skretting G, van Deurs B, Iversen TG (2001)
    Pathways followed by ricin and Shiga toxin into cells
    Histochem Cell Biol, 117 (2), 131-41
    DOI 10.1007/s00418-001-0346-2, PubMed 11935289
  30. Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2001)
    In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy
    Int J Cancer, 92 (5), 761-6
    DOI 10.1002/1097-0215(20010601)92:5<761::aid-ijc1238>3.0.co;2-4, PubMed 11340584
  31. Simonsen A, Stenmark H (2001)
    PX domains: attracted by phosphoinositides
    Nat Cell Biol, 3 (8), E179-82
    DOI 10.1038/35087112, PubMed 11483972
  32. Simonsen A, Wurmser AE, Emr SD, Stenmark H (2001)
    The role of phosphoinositides in membrane transport
    Curr Opin Cell Biol, 13 (4), 485-92
    DOI 10.1016/s0955-0674(00)00240-4, PubMed 11454456
  33. Skarstad K, Torheim N, Wold S, Lurz R, Messer W, Fossum S, Bach T (2001)
    The Escherichia coli SeqA protein binds specifically to two sites in fully and hemimethylated oriC and has the capacity to inhibit DNA replication and affect chromosome topology
    Biochimie, 83 (1), 49-51
    DOI 10.1016/s0300-9084(00)01207-4, PubMed 11254974
  34. Slagsvold T, Kraus I, Frønsdal K, Saatcioglu F (2001)
    DNA binding-independent transcriptional activation by the androgen receptor through triggering of coactivators
    J Biol Chem, 276 (33), 31030-6
    DOI 10.1074/jbc.M104310200, PubMed 11429409
  35. Slomińska M, Wegrzyn A, Konopa G, Skarstad K, Wegrzyn G (2001)
    SeqA, the Escherichia coli origin sequestration protein, is also a specific transcription factor
    Mol Microbiol, 40 (6), 1371-9
    DOI 10.1046/j.1365-2958.2001.02480.x, PubMed 11442835
  36. Stenmark H (2001)
    Introduction. Trafficking of lipids
    Semin Cell Dev Biol, 12 (2), 135-7
    DOI 10.1006/scdb.2000.0230, PubMed 11292379
  37. Stenmark H, Gillooly DJ (2001)
    Intracellular trafficking and turnover of phosphatidylinositol 3-phosphate
    Semin Cell Dev Biol, 12 (2), 193-9
    DOI 10.1006/scdb.2000.0236, PubMed 11292385
  38. Stenmark H, Olkkonen VM (2001)
    The Rab GTPase family
    Genome Biol, 2 (5), REVIEWS3007
    DOI 10.1186/gb-2001-2-5-reviews3007, PubMed 11387043
  39. Stenmark H, Olkkonen VM (2001)
    The Rab GTPase family
    Genome Biol., 2 (5), 3007.1
  40. Strømhaug PE, Bevan A, Dunn WA (2001)
    GSA11 encodes a unique 208-kDa protein required for pexophagy and autophagy in Pichia pastoris
    J Biol Chem, 276 (45), 42422-35
    DOI 10.1074/jbc.M104087200, PubMed 11533052
  41. Torgersen ML, Skretting G, van Deurs B, Sandvig K (2001)
    Internalization of cholera toxin by different endocytic mechanisms
    J Cell Sci, 114 (Pt 20), 3737-47
    DOI 10.1242/jcs.114.20.3737, PubMed 11707525
  42. Weigel C, Messer W, Preiss S, Welzeck M, Morigen, Boye E (2001)
    The sequence requirements for a functional Escherichia coli replication origin are different for the chromosome and a minichromosome
    Mol Microbiol, 40 (2), 498-507
    DOI 10.1046/j.1365-2958.2001.02409.x, PubMed 11309131
  43. Zheng W, Li Z, Skarstad K, Crooke E (2001)
    Mutations in DnaA protein suppress the growth arrest of acidic phospholipid-deficient Escherichia coli cells
    EMBO J, 20 (5), 1164-72
    DOI 10.1093/emboj/20.5.1164, PubMed 11230139

Publications 2000

  1. Bernander R, Skarstad K (2000)
    Mapping of a chromosome replication origin in an archaeon
    Trends Microbiol, 8 (12), 535-7
    DOI 10.1016/s0966-842x(00)01878-3, PubMed 11115744
  2. Blankson H, Grotterød EM, Seglen PO (2000)
    Prevention of toxin-induced cytoskeletal disruption and apoptotic liver cell death by the grapefruit flavonoid, naringin
    Cell Death Differ, 7 (8), 739-46
    DOI 10.1038/sj.cdd.4400705, PubMed 10918448
  3. Boye E, Løbner-Olesen A, Skarstad K (2000)
    Limiting DNA replication to once and only once
    EMBO Rep, 1 (6), 479-83
    DOI 10.1093/embo-reports/kvd116, PubMed 11263490
  4. Bremnes T, Paasche JD, Mehlum A, Sandberg C, Bremnes B, Attramadal H (2000)
    Regulation and intracellular trafficking pathways of the endothelin receptors
    J Biol Chem, 275 (23), 17596-604
    DOI 10.1074/jbc.M000142200, PubMed 10747877
  5. Dahl C, Haug LS, Spilsberg B, Johansen J, Ostvold AC, Diemer NH (2000)
    Reduced [3H]IP3 binding but unchanged IP3 receptor levels in the rat hippocampus CA1 region following transient global ischemia and tolerance induction
    Neurochem Int, 36 (4-5), 379-88
    DOI 10.1016/s0197-0186(99)00129-1, PubMed 10733005
  6. Day PJ, Owens SR, Wesche J, Olsnes S, Roberts LM, Lord JM (2000)
    An interaction between ricin and calreticulin that may have implications for toxin trafficking
    J Biol Chem, 276 (10), 7202-8
    DOI 10.1074/jbc.M009499200, PubMed 11113144
  7. Duclos S, Diez R, Garin J, Papadopoulou B, Descoteaux A, Stenmark H, Desjardins M (2000)
    Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages
    J Cell Sci, 113 Pt 19, 3531-41
    DOI 10.1242/jcs.113.19.3531, PubMed 10984443
  8. Ebbesen P, Pettersen EO, Denekamp J, Littbrand B, Keski-Oja J, Schousboe A, Sonnewald U, Amellem O, Zachar V (2000)
    Hypoxia, normoxia and hyperoxia--terminology for medical in vitro cell biology
    Acta Oncol, 39 (2), 247-8
    DOI 10.1080/028418600430888, PubMed 10859022
  9. Eidem JK, Rasmussen IB, Lunde E, Gregers TF, Rees AR, Bogen B, Sandlie I (2000)
    Recombinant antibodies as carrier proteins for sub-unit vaccines: influence of mode of fusion on protein production and T-cell activation
    J Immunol Methods, 245 (1-2), 119-31
    DOI 10.1016/s0022-1759(00)00274-x, PubMed 11042289
  10. Eliassen TM, Frøystad MK, Dannevig BH, Jankowska M, Brech A, Falk K, Romøren K, Gjøen T (2000)
    Initial events in infectious salmon anemia virus infection: evidence for the requirement of a low-pH step
    J Virol, 74 (1), 218-27
    DOI 10.1128/jvi.74.1.218-227.2000, PubMed 10590109
  11. Falnes PO (2000)
    Design of toxins that can be activated by cell-specific proteases and their potential use in targeted cell killing
    Int J Med Microbiol, 290 (4-5), 471-6
    DOI 10.1016/S1438-4221(00)80068-5, PubMed 11111928
  12. Falnes PO, Ariansen S, Sandvig K, Olsnes S (2000)
    Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin
    J Biol Chem, 275 (6), 4363-8
    DOI 10.1074/jbc.275.6.4363, PubMed 10660606
  13. Falnes PO, Sandvig K (2000)
    Penetration of protein toxins into cells
    Curr Opin Cell Biol, 12 (4), 407-13
    DOI 10.1016/s0955-0674(00)00109-5, PubMed 10873820
  14. Fengsrud M, Erichsen ES, Berg TO, Raiborg C, Seglen PO (2000)
    Ultrastructural characterization of the delimiting membranes of isolated autophagosomes and amphisomes by freeze-fracture electron microscopy
    Eur J Cell Biol, 79 (12), 871-82
    DOI 10.1078/0171-9335-00125, PubMed 11152279
  15. Fengsrud M, Raiborg C, Berg TO, Strømhaug PE, Ueno T, Erichsen ES, Seglen PO (2000)
    Autophagosome-associated variant isoforms of cytosolic enzymes
    Biochem J, 352 Pt 3 (Pt 3), 773-81
    DOI 10.1042/0264-6021:3520773, PubMed 11104685
  16. Gaullier JM, Ronning E, Gillooly DJ, Stenmark H (2000)
    Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues
    J Biol Chem, 275 (32), 24595-600
    DOI 10.1074/jbc.M906554199, PubMed 10807926
  17. Gillooly DJ, Morrow IC, Lindsay M, Gould R, Bryant NJ, Gaullier JM, Parton RG, Stenmark H (2000)
    Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
    EMBO J, 19 (17), 4577-88
    DOI 10.1093/emboj/19.17.4577, PubMed 10970851
  18. Grallert B, Kearsey SE, Lenhard M, Carlson CR, Nurse P, Boye E, Labib K (2000)
    A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls
    J Cell Sci, 113 ( Pt 8), 1447-58
    DOI 10.1242/jcs.113.8.1447, PubMed 10725227
  19. Grimmer S, Iversen TG, van Deurs B, Sandvig K (2000)
    Endosome to Golgi transport of ricin is regulated by cholesterol
    Mol Biol Cell, 11 (12), 4205-16
    DOI 10.1091/mbc.11.12.4205, PubMed 11102518
  20. Klingenberg O, Wiedlocha A, Rapak A, Khnykin D, Citores L, Olsnes S (2000)
    Requirement for C-terminal end of fibroblast growth factor receptor 4 in translocation of acidic fibroblast growth factor to cytosol and nucleus
    J Cell Sci, 113 ( Pt 10), 1827-38
    DOI 10.1242/jcs.113.10.1827, PubMed 10769213
  21. Klingenberg O, Wiedocha A, Citores L, Olsnes S (2000)
    Requirement of phosphatidylinositol 3-kinase activity for translocation of exogenous aFGF to the cytosol and nucleus
    J Biol Chem, 275 (16), 11972-80
    DOI 10.1074/jbc.275.16.11972, PubMed 10766827
  22. Kolpakova E, Frengen E, Stokke T, Olsnes S (2000)
    Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein
    Biochem J, 352 Pt 3 (Pt 3), 629-35
    DOI 10.1042/0264-6021:3520629, PubMed 11104667
  23. Llorente A, van Deurs B, Garred O, Eker P, Sandvig K (2000)
    Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway
    J Cell Sci, 113 ( Pt 7), 1213-21
    DOI 10.1242/jcs.113.7.1213, PubMed 10704372
  24. Løvdal T, Andersen E, Brech A, Berg T (2000)
    Fc receptor mediated endocytosis of small soluble immunoglobulin G immune complexes in Kupffer and endothelial cells from rat liver
    J Cell Sci, 113 ( Pt 18), 3255-66
    DOI 10.1242/jcs.113.18.3255, PubMed 10954423
  25. Nicoziani P, Vilhardt F, Llorente A, Hilout L, Courtoy PJ, Sandvig K, van Deurs B (2000)
    Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor
    Mol Biol Cell, 11 (2), 481-95
    DOI 10.1091/mbc.11.2.481, PubMed 10679008
  26. Olsnes S, Falnes PO (2000)
    Probing pores with peptide plugs. Topology of membrane-inserted diphtheria toxin
    J Gen Physiol, 115 (4), 417-20
    DOI 10.1085/jgp.115.4.417, PubMed 10736309
  27. Pihl A, Bruland OS (2000)
    Oral presentations in science and medicine. An art in decline?
    Anticancer Res, 20 (5A), 2795-9
    PubMed 11062686
  28. Prosch-Danielsen L, Simonsen A (2000)
    Palaeoecological investigations towards the reconstruction of the history of forest clearances and coastal heathlands in south-western Norway
    Veg. Hist. Archaeobot., 9 (4), 189-204
    DOI 10.1007/BF01294634
  29. Sandvig K, Grimmer S, Iversen TG, Rodal K, Torgersen ML, Nicoziani P, van Deurs B (2000)
    Ricin transport into cells: studies of endocytosis and intracellular transport
    Int J Med Microbiol, 290 (4-5), 415-20
    DOI 10.1016/S1438-4221(00)80055-7, PubMed 11111920
  30. Sandvig K, Llorente A, Rodal SK, Eker P, Garred O, Stahlhut M, van Deurs B (2000)
    Apical macropinocytosis in polarized MDCK cells: regulation by N-ethylmaleimide-sensitive proteins
    Eur J Cell Biol, 79 (7), 447-57
    DOI 10.1078/0171-9335-00071, PubMed 10961444
  31. Sandvig K, van Deurs B (2000)
    Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives
    EMBO J, 19 (22), 5943-50
    DOI 10.1093/emboj/19.22.5943, PubMed 11080141
  32. Selbo PK, Sandvig K, Kirveliene V, Berg K (2000)
    Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization
    Biochim Biophys Acta, 1475 (3), 307-13
    DOI 10.1016/s0304-4165(00)00082-9, PubMed 10913830
  33. Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2000)
    Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
    Int J Cancer, 87 (6), 853-9
    DOI 10.1002/1097-0215(20000915)87:6<853::aid-ijc15>3.0.co;2-0, PubMed 10956397
  34. Skarstad K, Lueder G, Lurz R, Speck C, Messer W (2000)
    The Escherichia coli SeqA protein binds specifically and co-operatively to two sites in hemimethylated and fully methylated oriC
    Mol Microbiol, 36 (6), 1319-26
    DOI 10.1046/j.1365-2958.2000.01943.x, PubMed 10931282
  35. Slagsvold T, Kraus I, Bentzen T, Palvimo J, Saatcioglu F (2000)
    Mutational analysis of the androgen receptor AF-2 (activation function 2) core domain reveals functional and mechanistic differences of conserved residues compared with other nuclear receptors
    Mol Endocrinol, 14 (10), 1603-17
    DOI 10.1210/mend.14.10.0544, PubMed 11043576
  36. Stahlhut M, Sandvig K, van Deurs B (2000)
    Caveolae: uniform structures with multiple functions in signaling, cell growth, and cancer
    Exp Cell Res, 261 (1), 111-8
    DOI 10.1006/excr.2000.4960, PubMed 11082281
  37. Stenmark H (2000)
    Cycling lipids
    Curr Biol, 10 (2), R57-9
    DOI 10.1016/s0960-9822(00)00279-7, PubMed 10662657
  38. Torheim NK, Boye E, Løbner-Olesen A, Stokke T, Skarstad K (2000)
    The Escherichia coli SeqA protein destabilizes mutant DnaA204 protein
    Mol Microbiol, 37 (3), 629-38
    DOI 10.1046/j.1365-2958.2000.02031.x, PubMed 10931356
  39. Urbé S, Mills IG, Stenmark H, Kitamura N, Clague MJ (2000)
    Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate
    Mol Cell Biol, 20 (20), 7685-92
    DOI 10.1128/MCB.20.20.7685-7692.2000, PubMed 11003664
  40. von Freiesleben U, Krekling MA, Hansen FG, Løbner-Olesen A (2000)
    The eclipse period of Escherichia coli
    EMBO J, 19 (22), 6240-8
    DOI 10.1093/emboj/19.22.6240, PubMed 11080169
  41. Wesche J, Wiedłocha A, Falnes PO, Choe S, Olsnes S (2000)
    Externally added aFGF mutants do not require extensive unfolding for transport to the cytosol and the nucleus in NIH/3T3 cells
    Biochemistry, 39 (49), 15091-100
    DOI 10.1021/bi001831k, PubMed 11106487

Publications 1999

  1. Baekkevold ES, Jahnsen FL, Johansen FE, Bakke O, Gaudernack G, Brandtzaeg P, Haraldsen G (1999)
    Culture characterization of differentiated high endothelial venule cells from human tonsils
    Lab Invest, 79 (3), 327-36
    PubMed 10092069
  2. Berg K, Selbo PK, Prasmickaite L, Tjelle TE, Sandvig K, Moan J, Gaudernack G, Fodstad O, Kjølsrud S, Anholt H, Rodal GH, Rodal SK, Høgset A (1999)
    Photochemical internalization: a novel technology for delivery of macromolecules into cytosol
    Cancer Res, 59 (6), 1180-3
    PubMed 10096543
  3. Callaghan J, Nixon S, Bucci C, Toh BH, Stenmark H (1999)
    Direct interaction of EEA1 with Rab5b
    Eur J Biochem, 265 (1), 361-6
    DOI 10.1046/j.1432-1327.1999.00743.x, PubMed 10491193
  4. Callaghan J, Simonsen A, Gaullier JM, Toh BH, Stenmark H (1999)
    The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer
    Biochem J, 338 ( Pt 2) (Pt 2), 539-43
    DOI 10.1042/0264-6021:3380539, PubMed 10024533
  5. Carlson CR, Grallert B, Stokke T, Boye E (1999)
    Regulation of the start of DNA replication in Schizosaccharomyces pombe
    J Cell Sci, 112 ( Pt 6), 939-46
    DOI 10.1242/jcs.112.6.939, PubMed 10036243
  6. Citores L, Wesche J, Kolpakova E, Olsnes S (1999)
    Uptake and intracellular transport of acidic fibroblast growth factor: evidence for free and cytoskeleton-anchored fibroblast growth factor receptors
    Mol Biol Cell, 10 (11), 3835-48
    DOI 10.1091/mbc.10.11.3835, PubMed 10564275
  7. Corvera S, D'Arrigo A, Stenmark H (1999)
    Phosphoinositides in membrane traffic
    Curr Opin Cell Biol, 11 (4), 460-5
    DOI 10.1016/S0955-0674(99)80066-0, PubMed 10449332
  8. Falnes PO, Welker R, Kräusslich HG, Olsnes S (1999)
    Toxins that are activated by HIV type-1 protease through removal of a signal for degradation by the N-end-rule pathway
    Biochem J, 343 Pt 1 (Pt 1), 199-207
    DOI 10.1042/0264-6021:3430199, PubMed 10493930
  9. Furre T, Bergstrand ES, Pedersen E, Koritzinsky M, Olsen DR, Hole EO, Pettersen EO (1999)
    Measurement of dose rate at the interface of cell culture medium and glass dishes by means of ESR dosimetry using thin films of alanine
    Radiat Res, 152 (1), 76-82
    DOI 10.2307/3580052, PubMed 10381844
  10. Furre T, Koritzinsky M, Olsen DR, Pettersen EO (1999)
    Inverse dose-rate effect due to pre-mitotic accumulation during continuous low dose-rate irradiation of cervix carcinoma cells
    Int J Radiat Biol, 75 (6), 699-707
    DOI 10.1080/095530099140032, PubMed 10404999
  11. Gaullier JM, Gillooly D, Simonsen A, Stenmark H (1999)
    Regulation of endocytic membrane traffic by phosphatidylinositol 3-phosphate
    Biochem Soc Trans, 27 (4), 666-70
    DOI 10.1042/bst0270666, PubMed 10917663
  12. Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H (1999)
    FYVE finger proteins as effectors of phosphatidylinositol 3-phosphate
    Chem Phys Lipids, 98 (1-2), 87-94
    DOI 10.1016/s0009-3084(99)00021-3, PubMed 10358931
  13. Grallert A, Grallert B, Zilahi E, Szilagyi Z, Sipiczki M (1999)
    Eleven novel sep genes of Schizosaccharomyces pombe required for efficient cell separation and sexual differentiation
    Yeast, 15 (8), 669-86
    DOI 10.1002/(SICI)1097-0061(19990615)15:8<669::AID-YEA411>3.0.CO;2-K, PubMed 10392445
  14. Hjertner O, Torgersen ML, Seidel C, Hjorth-Hansen H, Waage A, Børset M, Sundan A (1999)
    Hepatocyte growth factor (HGF) induces interleukin-11 secretion from osteoblasts: a possible role for HGF in myeloma-associated osteolytic bone disease
    Blood, 94 (11), 3883-8
    PubMed 10572104
  15. Klingenberg O, Wiedlocha A, Olsnes S (1999)
    Effects of mutations of a phosphorylation site in an exposed loop in acidic fibroblast growth factor
    J Biol Chem, 274 (25), 18081-6
    DOI 10.1074/jbc.274.25.18081, PubMed 10364261
  16. Kraggerud SM, Berner A, Bryne M, Pettersen EO, Fossa SD (1999)
    Spermatocytic seminoma as compared to classical seminoma: an immunohistochemical and DNA flow cytometric study
    APMIS, 107 (3), 297-302
    DOI 10.1111/j.1699-0463.1999.tb01557.x, PubMed 10223302
  17. Lyngstadaas A, Løbner-Olesen A, Grelland E, Boye E (1999)
    The gene for 2-phosphoglycolate phosphatase (gph) in Escherichia coli is located in the same operon as dam and at least five other diverse genes
    Biochim Biophys Acta, 1472 (1-2), 376-84
    DOI 10.1016/s0304-4165(99)00146-4, PubMed 10572959
  18. Løbner-Olesen A (1999)
    Distribution of minichromosomes in individual Escherichia coli cells: implications for replication control
    EMBO J, 18 (6), 1712-21
    DOI 10.1093/emboj/18.6.1712, PubMed 10075940
  19. Olsnes S (1999)
    [The Nobel Prize in physiology and medicine]
    Tidsskr Nor Laegeforen, 119 (30), 4450
    PubMed 10827478
  20. Rodal SK, Skretting G, Garred O, Vilhardt F, van Deurs B, Sandvig K (1999)
    Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
    Mol Biol Cell, 10 (4), 961-74
    DOI 10.1091/mbc.10.4.961, PubMed 10198050
  21. Sandvig K, van Deurs B (1999)
    Endocytosis and intracellular transport of ricin: recent discoveries
    FEBS Lett, 452 (1-2), 67-70
    DOI 10.1016/s0014-5793(99)00529-3, PubMed 10376680
  22. Simonsen A, Gaullier JM, D'Arrigo A, Stenmark H (1999)
    The Rab5 effector EEA1 interacts directly with syntaxin-6
    J Biol Chem, 274 (41), 28857-60
    DOI 10.1074/jbc.274.41.28857, PubMed 10506127
  23. Skretting G, Torgersen ML, van Deurs B, Sandvig K (1999)
    Endocytic mechanisms responsible for uptake of GPI-linked diphtheria toxin receptor
    J Cell Sci, 112 ( Pt 22), 3899-909
    DOI 10.1242/jcs.112.22.3899, PubMed 10547351
  24. Stenmark H, Aasland R (1999)
    FYVE-finger proteins--effectors of an inositol lipid
    J Cell Sci, 112 ( Pt 23), 4175-83
    DOI 10.1242/jcs.112.23.4175, PubMed 10564636
  25. Synnes M, Prydz K, Løvdal T, Brech A, Berg T (1999)
    Fluid phase endocytosis and galactosyl receptor-mediated endocytosis employ different early endosomes
    Biochim Biophys Acta, 1421 (2), 317-28
    DOI 10.1016/s0005-2736(99)00134-0, PubMed 10518701
  26. Torheim NK, Skarstad K (1999)
    Escherichia coli SeqA protein affects DNA topology and inhibits open complex formation at oriC
    EMBO J, 18 (17), 4882-8
    DOI 10.1093/emboj/18.17.4882, PubMed 10469666
  27. Vilhardt F, Nielsen M, Sandvig K, van Deurs B (1999)
    Urokinase-type plasminogen activator receptor is internalized by different mechanisms in polarized and nonpolarized Madin-Darby canine kidney epithelial cells
    Mol Biol Cell, 10 (1), 179-95
    DOI 10.1091/mbc.10.1.179, PubMed 9880335
  28. Wesche J, Rapak A, Olsnes S (1999)
    Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol
    J Biol Chem, 274 (48), 34443-9
    DOI 10.1074/jbc.274.48.34443, PubMed 10567425
  29. Wiedłocha A (1999)
    Following angiogenin during angiogenesis: a journey from the cell surface to the nucleolus
    Arch Immunol Ther Exp (Warsz), 47 (5), 299-305
    PubMed 10604235
  30. Yuan W, Stromhaug PE, Dunn WA (1999)
    Glucose-induced autophagy of peroxisomes in Pichia pastoris requires a unique E1-like protein
    Mol Biol Cell, 10 (5), 1353-66
    DOI 10.1091/mbc.10.5.1353, PubMed 10233149

Publications 1998

  1. Amellem O, Sandvik JA, Stokke T, Pettersen EO (1998)
    The retinoblastoma protein-associated cell cycle arrest in S-phase under moderate hypoxia is disrupted in cells expressing HPV18 E7 oncoprotein
    Br J Cancer, 77 (6), 862-72
    DOI 10.1038/bjc.1998.143, PubMed 9528826
  2. Asai T, Bates DB, Boye E, Kogoma T (1998)
    Are minichromosomes valid model systems for DNA replication control? Lessons learned from Escherichia coli
    Mol Microbiol, 29 (3), 671-5
    DOI 10.1046/j.1365-2958.1998.00901.x, PubMed 9723907
  3. Berg TO, Fengsrud M, Strømhaug PE, Berg T, Seglen PO (1998)
    Isolation and characterization of rat liver amphisomes. Evidence for fusion of autophagosomes with both early and late endosomes
    J Biol Chem, 273 (34), 21883-92
    DOI 10.1074/jbc.273.34.21883, PubMed 9705327
  4. Bernander R, Stokke T, Boye E (1998)
    Flow cytometry of bacterial cells: comparison between different flow cytometers and different DNA stains
    Cytometry, 31 (1), 29-36
    DOI 10.1002/(sici)1097-0320(19980101)31:1<29::aid-cyto4>3.0.co;2-e, PubMed 9450522
  5. Drolsum L, Haaskjold E, Sandvig K (1998)
    Phacoemulsification in eyes with pseudoexfoliation
    J Cataract Refract Surg, 24 (6), 787-92
    DOI 10.1016/s0886-3350(98)80132-6, PubMed 9642589
  6. Falnes PO, Olsnes S (1998)
    Modulation of the intracellular stability and toxicity of diphtheria toxin through degradation by the N-end rule pathway
    EMBO J, 17 (2), 615-25
    DOI 10.1093/emboj/17.2.615, PubMed 9430652
  7. Frønsdal K, Engedal N, Slagsvold T, Saatcioglu F (1998)
    CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1
    J Biol Chem, 273 (48), 31853-9
    DOI 10.1074/jbc.273.48.31853, PubMed 9822653
  8. Gaullier JM, Simonsen A, D'Arrigo A, Bremnes B, Stenmark H, Aasland R (1998)
    FYVE fingers bind PtdIns(3)P
    Nature, 394 (6692), 432-3
    DOI 10.1038/28767, PubMed 9697764
  9. Gournier H, Stenmark H, Rybin V, Lippé R, Zerial M (1998)
    Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion
    EMBO J, 17 (7), 1930-40
    DOI 10.1093/emboj/17.7.1930, PubMed 9524116
  10. Grzelak I, Zaleska M, Olszewski WL (1998)
    Blood transfusions downregulate hematopoiesis and subsequently downregulate the immune response
    Transfusion, 38 (11-12), 1104-14
    DOI 10.1046/j.1537-2995.1998.38111299056323.x, PubMed 9838944
  11. Janson IM, Toomik R, O'Farrell F, Ek P (1998)
    KDEL motif interacts with a specific sequence in mammalian erd2 receptor
    Biochem Biophys Res Commun, 247 (2), 447-51
    DOI 10.1006/bbrc.1998.8809, PubMed 9642148
  12. Klingenberg O, Widlocha A, Rapak A, Muñoz R, Falnes P, Olsnes S (1998)
    Inability of the acidic fibroblast growth factor mutant K132E to stimulate DNA synthesis after translocation into cells
    J Biol Chem, 273 (18), 11164-72
    DOI 10.1074/jbc.273.18.11164, PubMed 9556604
  13. Kolpakova E, Wiedłocha A, Stenmark H, Klingenberg O, Falnes PO, Olsnes S (1998)
    Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor
    Biochem J, 336 ( Pt 1) (Pt 1), 213-22
    DOI 10.1042/bj3360213, PubMed 9806903
  14. Koritzinsky M, Furre T, Amellem O, Pettersen EO (1998)
    Survival of synchronized human NHIK 3025 cells irradiated aerobically following a prolonged treatment with extremely hypoxic conditions
    Int J Radiat Biol, 74 (4), 491-500
    DOI 10.1080/095530098141366, PubMed 9798960
  15. Kovács AL, Gordon PB, Grotterød EM, Seglen PO (1998)
    Inhibition of hepatocytic autophagy by adenosine, adenosine analogs and AMP
    Biol Chem, 379 (11), 1341-7
    DOI 10.1515/bchm.1998.379.11.1341, PubMed 9865607
  16. Llorente A, Rapak A, Schmid SL, van Deurs B, Sandvig K (1998)
    Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
    J Cell Biol, 140 (3), 553-63
    DOI 10.1083/jcb.140.3.553, PubMed 9456316
  17. Llorente A, van Deurs B, Sandvig K (1998)
    Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells
    FEBS Lett, 431 (2), 200-4
    DOI 10.1016/s0014-5793(98)00754-6, PubMed 9708902
  18. Loukianov EV, Loukianova T, Wiedlocha A, Olsnes S (1998)
    Variation in the proregion structure of heparin-binding EGF-like growth factor precursors
    Gene, 212 (1), 1-4
    DOI 10.1016/s0378-1119(98)00139-5, PubMed 9661657
  19. Lyngstadaas A, Sprenger GA, Boye E (1998)
    Impaired growth of an Escherichia coli rpe mutant lacking ribulose-5-phosphate epimerase activity
    Biochim Biophys Acta, 1381 (3), 319-30
    DOI 10.1016/s0304-4165(98)00046-4, PubMed 9729441
  20. Marcinkowska E, Wiedlocha A, Radzikowski C (1998)
    Evidence that phosphatidylinositol 3-kinase and p70S6K protein are involved in differentiation of HL-60 cells induced by calcitriol
    Anticancer Res, 18 (5A), 3507-14
    PubMed 9858932
  21. Mathiesen RH, Mo F, Eikenes A, Nyborg T, Larsen HB (1998)
    Existence of two crystal structures of the complex alpha-D-glucose center dot NaCl center dot H2O (2 : 1 : 1) verified by three-beam diffraction experiments
    Acta Crystallogr. Sect. A, 54, 338-347
    DOI 10.1107/S0108767397018849
  22. Olsnes S (1998)
    Shiga and Shiga-like toxins
    RECENT ADVANCES IN THE PATHOGENESIS OF GASTROINTESTINAL BACTERIAL INFECTIONS, 143-153
  23. Rundén E, Seglen PO, Haug FM, Ottersen OP, Wieloch T, Shamloo M, Laake JH (1998)
    Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism
    J Neurosci, 18 (18), 7296-305
    DOI 10.1523/JNEUROSCI.18-18-07296.1998, PubMed 9736650
  24. Samari HR, Seglen PO (1998)
    Inhibition of hepatocytic autophagy by adenosine, aminoimidazole-4-carboxamide riboside, and N6-mercaptopurine riboside. Evidence for involvement of amp-activated protein kinase
    J Biol Chem, 273 (37), 23758-63
    DOI 10.1074/jbc.273.37.23758, PubMed 9726984
  25. Simonsen A, Bremnes B, Rønning E, Aasland R, Stenmark H (1998)
    Syntaxin-16, a putative Golgi t-SNARE
    Eur J Cell Biol, 75 (3), 223-31
    DOI 10.1016/S0171-9335(98)80116-7, PubMed 9587053
  26. Simonsen A, Lippé R, Christoforidis S, Gaullier JM, Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H (1998)
    EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
    Nature, 394 (6692), 494-8
    DOI 10.1038/28879, PubMed 9697774
  27. Strømhaug PE, Berg TO, Fengsrud M, Seglen PO (1998)
    Purification and characterization of autophagosomes from rat hepatocytes
    Biochem J, 335 ( Pt 2) (Pt 2), 217-24
    DOI 10.1042/bj3350217, PubMed 9761717
  28. Vitale G, Rybin V, Christoforidis S, Thornqvist P, McCaffrey M, Stenmark H, Zerial M (1998)
    Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5
    EMBO J, 17 (7), 1941-51
    DOI 10.1093/emboj/17.7.1941, PubMed 9524117
  29. Vogel U, Sandvig K, van Deurs B (1998)
    Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells
    J Cell Sci, 111 ( Pt 6), 825-32
    DOI 10.1242/jcs.111.6.825, PubMed 9472010
  30. Waite RL, Sentry JW, Stenmark H, Toh BH (1998)
    Autoantibodies to a novel early endosome antigen 1
    Clin Immunol Immunopathol, 86 (1), 81-7
    DOI 10.1006/clin.1997.4455, PubMed 9434799
  31. Wesche J, Elliott JL, Falnes PO, Olsnes S, Collier RJ (1998)
    Characterization of membrane translocation by anthrax protective antigen
    Biochemistry, 37 (45), 15737-46
    DOI 10.1021/bi981436i, PubMed 9843379
  32. Wiedłocha A (1998)
    Novel protein toxin-based strategy for development of cytotoxic T lymphocyte vaccines
    Arch Immunol Ther Exp (Warsz), 46 (6), 341-6
    PubMed 9883312
  33. Wold S, Boye E, Slater S, Kleckner N, Skarstad K (1998)
    Effects of purified SeqA protein on oriC-dependent DNA replication in vitro
    EMBO J, 17 (14), 4158-65
    DOI 10.1093/emboj/17.14.4158, PubMed 9670030
  34. Zacchi P, Stenmark H, Parton RG, Orioli D, Lim F, Giner A, Mellman I, Zerial M, Murphy C (1998)
    Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells
    J Cell Biol, 140 (5), 1039-53
    DOI 10.1083/jcb.140.5.1039, PubMed 9490718
  35. Zalecki P, Radzikowski C, Olsnes S, Wiedłocha A (1998)
    Modulation by interleukin-2 of cellular response to fibroblast growth factor-1 in F69-3 fibrosarcoma cells
    Exp Cell Res, 244 (1), 61-70
    DOI 10.1006/excr.1998.4187, PubMed 9770349

Publications 1997

  1. Amellem O, Stokke T, Sandvik JA, Smedshammer L, Pettersen EO (1997)
    Hypoxia-induced apoptosis in human cells with normal p53 status and function, without any alteration in the nuclear protein level
    Exp Cell Res, 232 (2), 361-70
    DOI 10.1006/excr.1997.3497, PubMed 9168813
  2. Bates DB, Boye E, Asai T, Kogoma T (1997)
    The absence of effect of gid or mioC transcription on the initiation of chromosomal replication in Escherichia coli
    Proc Natl Acad Sci U S A, 94 (23), 12497-502
    DOI 10.1073/pnas.94.23.12497, PubMed 9356478
  3. Carlson CR, Grallert B, Bernander R, Stokke T, Boye E (1997)
    Measurement of nuclear DNA content in fission yeast by flow cytometry
    Yeast, 13 (14), 1329-35
    DOI 10.1002/(SICI)1097-0061(199711)13:14<1329::AID-YEA185>3.0.CO;2-M, PubMed 9392077
  4. D'Arrigo A, Bucci C, Toh BH, Stenmark H (1997)
    Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes
    Eur J Cell Biol, 72 (2), 95-103
    PubMed 9157016
  5. Garred O, Dubinina E, Polesskaya A, Olsnes S, Kozlov J, Sandvig K (1997)
    Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells
    J Biol Chem, 272 (17), 11414-9
    DOI 10.1074/jbc.272.17.11414, PubMed 9111051
  6. Grzelak I, Zaleska M, Olszewski WL (1997)
    Immune response after syngeneic and allogeneic blood cell transplantation
    Transplant Proc, 29 (4), 2181-2
    DOI 10.1016/s0041-1345(97)00283-2, PubMed 9193579
  7. Horiuchi H, Lippé R, McBride HM, Rubino M, Woodman P, Stenmark H, Rybin V, Wilm M, Ashman K, Mann M, Zerial M (1997)
    A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function
    Cell, 90 (6), 1149-59
    DOI 10.1016/s0092-8674(00)80380-3, PubMed 9323142
  8. Kraggerud SM, Jacobsen KD, Berner A, Stokke T, Holm R, Smedshammer L, Børresen-Dale AL, Fosså SD (1997)
    A comparison of different modes for the detection of p53 protein accumulation. A study of bladder cancer
    Pathol Res Pract, 193 (7), 471-8
    DOI 10.1016/s0344-0338(97)80099-4, PubMed 9342752
  9. Lanzrein M, Falnes PO, Sand O, Olsnes S (1997)
    Structure-function relationship of the ion channel formed by diphtheria toxin in Vero cell membranes
    J Membr Biol, 156 (2), 141-8
    DOI 10.1007/s002329900196, PubMed 9075645
  10. Lemichez E, Bomsel M, Devilliers G, vanderSpek J, Murphy JR, Lukianov EV, Olsnes S, Boquet P (1997)
    Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery
    Mol Microbiol, 23 (3), 445-57
    DOI 10.1111/j.1365-2958.1997.tb02669.x, PubMed 9044279
  11. Loukianov E, Loukianova T, Wiedlocha A, Olsnes S (1997)
    Expression of mRNA for a short form of heparin-binding EGF-like growth factor
    Gene, 195 (1), 81-6
    DOI 10.1016/s0378-1119(97)00161-3, PubMed 9300824
  12. Marcinkowska E, Wiedłocha A, Radzikowski C (1997)
    1,25-Dihydroxyvitamin D3 induced activation and subsequent nuclear translocation of MAPK is upstream regulated by PKC in HL-60 cells
    Biochem Biophys Res Commun, 241 (2), 419-26
    DOI 10.1006/bbrc.1997.7832, PubMed 9425286
  13. Muñoz R, Klingenberg O, Wiedłocha A, Rapak A, Falnes PO, Olsnes S (1997)
    Effect of mutation of cytoplasmic receptor domain and of genistein on transport of acidic fibroblast growth factor into cells
    Oncogene, 15 (5), 525-36
    DOI 10.1038/sj.onc.1201226, PubMed 9247306
  14. Olkkonen VM, Stenmark H (1997)
    Role of Rab GTPases in membrane traffic
    Int Rev Cytol, 176, 1-85
    DOI 10.1016/s0074-7696(08)61608-3, PubMed 9394917
  15. Polesskaia AN, Garred O, Olsnes S, Kozlov IuV (1997)
    [Self-inhibiting N-glycosidase activity of shigella toxin]
    Mol Biol (Mosk), 31 (3), 528-35
    PubMed 9297098
  16. Polesskaya AN, Garred O, Olsnes S, Kozlov YV (1997)
    Self-inhibition of N-glycosidase activity of shiga toxin
    Mol. Biol., 31 (3), 441-447
  17. Rapak A, Falnes PO, Olsnes S (1997)
    Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol
    Proc Natl Acad Sci U S A, 94 (8), 3783-8
    DOI 10.1073/pnas.94.8.3783, PubMed 9108055
  18. Sandvig K, Garred O, van Deurs B (1997)
    Intracellular transport and processing of protein toxins produced by enteric bacteria
    Adv Exp Med Biol, 412, 225-32
    DOI 10.1007/978-1-4899-1828-4_34, PubMed 9192018
  19. Seglen PO (1997)
    DNA ploidy and autophagic protein degradation as determinants of hepatocellular growth and survival
    Cell Biol Toxicol, 13 (4-5), 301-15
    DOI 10.1023/a:1007487425047, PubMed 9298250
  20. Strømhaug PE, Berg TO, Gjøen T, Seglen PO (1997)
    Differences between fluid-phase endocytosis (pinocytosis) and receptor-mediated endocytosis in isolated rat hepatocytes
    Eur J Cell Biol, 73 (1), 28-39
    PubMed 9174669
  21. Wiedłocha A (1997)
    Diphtheria toxin as a molecular tool in the study of acidic fibroblast growth factor signalling
    Arch Immunol Ther Exp (Warsz), 45 (5-6), 391-409
    PubMed 9437495

Publications 1996

  1. Allen ED, Burton RL, Webber SK, Haaskjold E, Sandvig K, Jyrkkiö H, Leite E, Nyström A, Wollensak J (1996)
    Comparison of a diffractive bifocal and a monofocal intraocular lens
    J Cataract Refract Surg, 22 (4), 446-51
    DOI 10.1016/s0886-3350(96)80040-x, PubMed 8733848
  2. Amellem O, Stokke T, Sandvik JA, Pettersen EO (1996)
    The retinoblastoma gene product is reversibly dephosphorylated and bound in the nucleus in S and G2 phases during hypoxic stress
    Exp Cell Res, 227 (1), 106-15
    DOI 10.1006/excr.1996.0255, PubMed 8806457
  3. Berg T, Gudmundsen O, Brech A, Kjeken R, Gjøen T (1996)
    Clathrin-dependent and clathrin-independent endocytosis in liver cells
    Z Gastroenterol, 34 Suppl 3, 92-4
    PubMed 8767476
  4. Boye E, Stokke T, Kleckner N, Skarstad K (1996)
    Coordinating DNA replication initiation with cell growth: differential roles for DnaA and SeqA proteins
    Proc Natl Acad Sci U S A, 93 (22), 12206-11
    DOI 10.1073/pnas.93.22.12206, PubMed 8901558
  5. Karlsen F, Kalantari M, Jenkins A, Pettersen E, Kristensen G, Holm R, Johansson B, Hagmar B (1996)
    Use of multiple PCR primer sets for optimal detection of human papillomavirus
    J Clin Microbiol, 34 (9), 2095-100
    DOI 10.1128/jcm.34.9.2095-2100.1996, PubMed 8862564
  6. Klingenberg O, Olsnes S (1996)
    Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin
    Biochem J, 313 ( Pt 2) (Pt 2), 647-53
    DOI 10.1042/bj3130647, PubMed 8573105
  7. Lanzrein M, Sand O, Olsnes S (1996)
    GPI-anchored diphtheria toxin receptor allows membrane translocation of the toxin without detectable ion channel activity
    EMBO J, 15 (4), 725-34
    DOI 10.1002/j.1460-2075.1996.tb00408.x, PubMed 8631294
  8. Llorente A, Garred O, Holm PK, Eker P, Jacobsen J, van Deurs B, Sandvig K (1996)
    Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells
    Exp Cell Res, 227 (2), 298-308
    DOI 10.1006/excr.1996.0279, PubMed 8831568
  9. Sandvig K, Garred O, van Deurs B (1996)
    Thapsigargin-induced transport of cholera toxin to the endoplasmic reticulum
    Proc Natl Acad Sci U S A, 93 (22), 12339-43
    DOI 10.1073/pnas.93.22.12339, PubMed 8901582
  10. Sandvig K, Garred O, van Helvoort A, van Meer G, van Deurs B (1996)
    Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells
    Mol Biol Cell, 7 (9), 1391-404
    DOI 10.1091/mbc.7.9.1391, PubMed 8885234
  11. Sandvig K, van Deurs B (1996)
    Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin
    Physiol Rev, 76 (4), 949-66
    DOI 10.1152/physrev.1996.76.4.949, PubMed 8874490
  12. Stenmark H, Aasland R, Toh BH, D'Arrigo A (1996)
    Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger
    J Biol Chem, 271 (39), 24048-54
    DOI 10.1074/jbc.271.39.24048, PubMed 8798641
  13. Tjelle TE, Brech A, Juvet LK, Griffiths G, Berg T (1996)
    Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation
    J Cell Sci, 109 ( Pt 12), 2905-14
    DOI 10.1242/jcs.109.12.2905, PubMed 9013338
  14. van Deurs B, Holm PK, Sandvig K (1996)
    Inhibition of the vacuolar H(+)-ATPase with bafilomycin reduces delivery of internalized molecules from mature multivesicular endosomes to lysosomes in HEp-2 cells
    Eur J Cell Biol, 69 (4), 343-50
    PubMed 8741216
  15. van Deurs B, von Bũlow F, Vilhardt F, Holm PK, Sandvig K (1996)
    Destabilization of plasma membrane structure by prevention of actin polymerization. Microtubule-dependent tubulation of the plasma membrane
    J Cell Sci, 109 ( Pt 7), 1655-65
    DOI 10.1242/jcs.109.7.1655, PubMed 8832388
  16. Waldum HL, Osmundsen H, Olsnes S, Sand O (1996)
    [The Anders Jahre medical awarad 1996]
    Tidsskr Nor Laegeforen, 116 (23), 2804-6
    PubMed 8928170
  17. Wiedłocha A (1996)
    Retrograde transport of acidic fibroblast growth factor as a part of the growth factor signaling
    Arch Immunol Ther Exp (Warsz), 44 (4), 201-7
    PubMed 9017159
  18. Wiedłocha A, Falnes PO, Rapak A, Muñoz R, Klingenberg O, Olsnes S (1996)
    Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization
    Mol Cell Biol, 16 (1), 270-80
    DOI 10.1128/MCB.16.1.270, PubMed 8524304

Publications 1995

  1. Barnett YA, Brennan LA, O'Farrell F, Hannigan BM (1995)
    Oxidant-induced stress response in lymphoid cells
    Biochem Mol Biol Int, 37 (2), 273-81
    PubMed 8673010
  2. ERIKSEN S, SAND O, LANZREIN M, SANDVIG K, OLSNES S (1995)
    CELL PENETRATION OF BACTERIAL PROTEIN TOXINS - RESPONSE
    Trends Microbiol., 3 (5), 167-168
    DOI 10.1016/S0966-842X(00)88912-X
  3. Falnes PO, Olsnes S (1995)
    Cell-mediated reduction and incomplete membrane translocation of diphtheria toxin mutants with internal disulfides in the A fragment
    J Biol Chem, 270 (35), 20787-93
    DOI 10.1074/jbc.270.35.20787, PubMed 7657662
  4. Falnes PO, Wiedłocha A, Rapak A, Olsnes S (1995)
    Farnesylation of CaaX-tagged diphtheria toxin A-fragment as a measure of transfer to the cytosol
    Biochemistry, 34 (35), 11152-9
    DOI 10.1021/bi00035a021, PubMed 7669773
  5. Garred O, Dubinina E, Holm PK, Olsnes S, van Deurs B, Kozlov JV, Sandvig K (1995)
    Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
    Exp Cell Res, 218 (1), 39-49
    DOI 10.1006/excr.1995.1128, PubMed 7737376
  6. Garred O, van Deurs B, Sandvig K (1995)
    Furin-induced cleavage and activation of Shiga toxin
    J Biol Chem, 270 (18), 10817-21
    DOI 10.1074/jbc.270.18.10817, PubMed 7738018
  7. Holen I, Gordon PB, Strømhaug PE, Berg TO, Fengsrud M, Brech A, Roos N, Berg T, Seglen PO (1995)
    Inhibition of asialoglycoprotein endocytosis and degradation in rat hepatocytes by protein phosphatase inhibitors
    Biochem J, 311 ( Pt 1) (Pt 1), 317-26
    DOI 10.1042/bj3110317, PubMed 7575471
  8. Holm PK, Eker P, Sandvig K, van Deurs B (1995)
    Phorbol myristate acetate selectively stimulates apical endocytosis via protein kinase C in polarized MDCK cells
    Exp Cell Res, 217 (1), 157-68
    DOI 10.1006/excr.1995.1075, PubMed 7867714
  9. Kjeken R, Brech A, Løvdal T, Roos N, Berg T (1995)
    Involvement of early and late lysosomes in the degradation of mannosylated ligands by rat liver endothelial cells
    Exp Cell Res, 216 (2), 290-8
    DOI 10.1006/excr.1995.1037, PubMed 7843273
  10. Lanzrein M, Garred O, Olsnes S, Sandvig K (1995)
    Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells
    Biochem J, 310 ( Pt 1) (Pt 1), 285-9
    DOI 10.1042/bj3100285, PubMed 7646457
  11. Mu FT, Callaghan JM, Steele-Mortimer O, Stenmark H, Parton RG, Campbell PL, McCluskey J, Yeo JP, Tock EP, Toh BH (1995)
    EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif
    J Biol Chem, 270 (22), 13503-11
    DOI 10.1074/jbc.270.22.13503, PubMed 7768953
  12. Singer-Krüger B, Stenmark H, Zerial M (1995)
    Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway
    J Cell Sci, 108 ( Pt 11), 3509-21
    DOI 10.1242/jcs.108.11.3509, PubMed 8586662
  13. Stenmark H, Vitale G, Ullrich O, Zerial M (1995)
    Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion
    Cell, 83 (3), 423-32
    DOI 10.1016/0092-8674(95)90120-5, PubMed 8521472
  14. Valdizan EM, Loukianov EV, Olsnes S (1995)
    Induction of toxin sensitivity in insect cells by infection with baculovirus encoding diphtheria toxin receptor
    J Biol Chem, 270 (28), 16879-85
    DOI 10.1074/jbc.270.28.16879, PubMed 7622504
  15. van Deurs B, Holm PK, Kayser L, Sandvig K (1995)
    Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes
    Eur J Cell Biol, 66 (4), 309-23
    PubMed 7544728
  16. Vitale G, Alexandrov K, Ullrich O, Horiuchi H, Giner A, Dobson C, Baykova O, Gournier H, Stenmark H, Zerial M (1995)
    The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic
    Cold Spring Harb Symp Quant Biol, 60, 211-20
    DOI 10.1101/sqb.1995.060.01.024, PubMed 8824393
  17. Wiedłocha A, Falnes PO, Rapak A, Klingenberg O, Muñoz R, Olsnes S (1995)
    Translocation of cytosol of exogenous, CAAX-tagged acidic fibroblast growth factor
    J Biol Chem, 270 (51), 30680-5
    DOI 10.1074/jbc.270.51.30680, PubMed 8530506
  18. Aas AT, Tønnessen TI, Brun A, Salford LG (1995)
    Growth inhibition of rat glioma cells in vitro and in vivo by aspirin
    J Neurooncol, 24 (2), 171-80
    DOI 10.1007/BF01078487, PubMed 7562004

Publications 1994

  1. de Hoop MJ, Huber LA, Stenmark H, Williamson E, Zerial M, Parton RG, Dotti CG (1994)
    The involvement of the small GTP-binding protein Rab5a in neuronal endocytosis
    Neuron, 13 (1), 11-22
    DOI 10.1016/0896-6273(94)90456-1, PubMed 8043272
  2. Eker P, Holm PK, van Deurs B, Sandvig K (1994)
    Selective regulation of apical endocytosis in polarized Madin-Darby canine kidney cells by mastoparan and cAMP
    J Biol Chem, 269 (28), 18607-15
    PubMed 8034609
  3. Eriksen S, Olsnes S, Sandvig K, Sand O (1994)
    Diphtheria toxin at low pH depolarizes the membrane, increases the membrane conductance and induces a new type of ion channel in Vero cells
    EMBO J, 13 (19), 4433-9
    DOI 10.1002/j.1460-2075.1994.tb06765.x, PubMed 7523112
  4. Falnes PO, Choe S, Madshus IH, Wilson BA, Olsnes S (1994)
    Inhibition of membrane translocation of diphtheria toxin A-fragment by internal disulfide bridges
    J Biol Chem, 269 (11), 8402-7
    PubMed 8132565
  5. Lanzrein M, Schlegel A, Kempf C (1994)
    Entry and uncoating of enveloped viruses
    Biochem J, 302 ( Pt 2) (Pt 2), 313-20
    DOI 10.1042/bj3020313, PubMed 8092981
  6. Madshus IH, Wiedlocha A, Sandvig K (1994)
    Intermediates in translocation of diphtheria toxin across the plasma membrane
    J Biol Chem, 269 (6), 4648-52
    PubMed 7508447
  7. SANDVIG K, GARRED O, HOLM PK, VANDEURS B (1994)
    ENTRY OF SHIGA TOXIN INTO CELLS
    INT CONGR SER, 1072, 139-146
  8. Sandvig K, Ryd M, Garred O, Schweda E, Holm PK, van Deurs B (1994)
    Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP
    J Cell Biol, 126 (1), 53-64
    DOI 10.1083/jcb.126.1.53, PubMed 8027186
  9. Sandvig K, van Deurs B (1994)
    Endocytosis and intracellular sorting of ricin and Shiga toxin
    FEBS Lett, 346 (1), 99-102
    DOI 10.1016/0014-5793(94)00281-9, PubMed 8206167
  10. Sandvig K, van Deurs B (1994)
    Endocytosis without clathrin
    Trends Cell Biol, 4 (8), 275-7
    DOI 10.1016/0962-8924(94)90211-9, PubMed 14731589
  11. SANDVIG K, VANDEURS B (1994)
    ENTRY OF SHIGA TOXIN INTO CELLS
    ZBL BAKT S, 24, 365-374
  12. Singer-Krüger B, Stenmark H, Düsterhöft A, Philippsen P, Yoo JS, Gallwitz D, Zerial M (1994)
    Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast
    J Cell Biol, 125 (2), 283-98
    DOI 10.1083/jcb.125.2.283, PubMed 8163546
  13. Wiedłocha A, Falnes PO, Madshus IH, Sandvig K, Olsnes S (1994)
    Dual mode of signal transduction by externally added acidic fibroblast growth factor
    Cell, 76 (6), 1039-51
    DOI 10.1016/0092-8674(94)90381-6, PubMed 7511061

Publications 1993

  1. Ariansen S, Afanasiev BN, Moskaug JO, Stenmark H, Madshus IH, Olsnes S (1993)
    Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region
    Biochemistry, 32 (1), 83-90
    DOI 10.1021/bi00052a012, PubMed 8418864
  2. Aullo P, Giry M, Olsnes S, Popoff MR, Kocks C, Boquet P (1993)
    A chimeric toxin to study the role of the 21 kDa GTP binding protein rho in the control of actin microfilament assembly
    EMBO J, 12 (3), 921-31
    DOI 10.1002/j.1460-2075.1993.tb05733.x, PubMed 8458345
  3. Banning DP, O'Farrell F, Gooderham NJ (1993)
    Activation of the food derived carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by rat pleural cavity inflammatory cells
    Carcinogenesis, 14 (12), 2457-62
    DOI 10.1093/carcin/14.12.2457, PubMed 8269612
  4. BERG T, BRECH A, KJEKEN R, ROOS N (1993)
    PRELYSOSOMAL DEGRADATION IN RAT-LIVER ENDOTHELIAL-CELLS
    CELLS OF THE HEPATIC SINUSOID, VOL 4, 426-430
  5. Esbensen QY, Falnes PO, Olsnes S, Madshus IH (1993)
    Subcloning and characterization of the binding domain of fragment B of diphtheria toxin
    Biochem J, 294 ( Pt 3) (Pt 3), 663-6
    DOI 10.1042/bj2940663, PubMed 8379922
  6. Hansen SH, Sandvig K, van Deurs B (1993)
    Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors
    J Cell Biol, 123 (1), 89-97
    DOI 10.1083/jcb.123.1.89, PubMed 8408209
  7. Hansen SH, Sandvig K, van Deurs B (1993)
    Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification
    J Cell Biol, 121 (1), 61-72
    DOI 10.1083/jcb.121.1.61, PubMed 8458873
  8. Holm PK, Hansen SH, Sandvig K, van Deurs B (1993)
    Endocytosis of desmosomal plaques depends on intact actin filaments and leads to a nondegradative compartment
    Eur J Cell Biol, 62 (2), 362-71
    PubMed 7925492
  9. Loukianov EV, Olsnes S (1993)
    New cloning opportunities with the use of noncomplementary SfiI adaptors
    Biotechniques, 15 (6), 980-2
    PubMed 8292350
  10. Ludt J, Sandvig K, Olsnes S (1993)
    Rapid increase in pH set-point of the Na(+)-in-dependent chloride/bicarbonate antiporter in Vero cells exposed to heat shock
    J Membr Biol, 134 (2), 143-53
    DOI 10.1007/BF00232750, PubMed 8411117
  11. Melby EL, Jacobsen J, Olsnes S, Sandvig K (1993)
    Entry of protein toxins in polarized epithelial cells
    Cancer Res, 53 (8), 1755-60
    PubMed 8467493
  12. Moskaug JO, Prydz K, Olsnes S (1993)
    Rapid cellular removal of a membrane-inserted foreign polypeptide
    Biochem J, 291 ( Pt 2) (Pt 2), 473-7
    DOI 10.1042/bj2910473, PubMed 8484728
  13. Olsnes S, van Deurs B, Sandvig K (1993)
    Protein toxins acting on intracellular targets: cellular uptake and translocation to the cytosol
    Med Microbiol Immunol, 182 (2), 51-61
    DOI 10.1007/BF00189373, PubMed 8392658
  14. Ottestad L, Andersen TI, Nesland JM, Skrede M, Tveit KM, Nustad K, Børresen AL (1993)
    Amplification of c-erbB-2, int-2 and c-myc genes in node-negative breast carcinomas. Relationship to prognosis
    Acta Oncol, 32 (3), 289-94
    DOI 10.3109/02841869309093597, PubMed 8100712
  15. Ottestad L, Pettersen EO, Nesland JM, Hannisdal E, Fosså SD, Tveit KM (1993)
    Flow cytometric DNA analysis as prognostic factor in human breast carcinoma
    Pathol Res Pract, 189 (4), 405-10
    DOI 10.1016/S0344-0338(11)80327-4, PubMed 8351241
  16. Sandvig K, Dubinina E, Garred O, Prydz K, Kozlov JV, Hansen SH, Van Deurs B (1993)
    Entry of Shiga toxin into cells
    Zentralbl Bakteriol, 278 (2-3), 296-305
    DOI 10.1016/s0934-8840(11)80846-7, PubMed 8347933
  17. Sandvig K, Garred O, Holm PK, van Deurs B (1993)
    Endocytosis and intracellular transport of protein toxins
    Biochem Soc Trans, 21 ( Pt 3) (3), 707-11
    DOI 10.1042/bst0210707, PubMed 8224494
  18. Ullrich O, Stenmark H, Alexandrov K, Huber LA, Kaibuchi K, Sasaki T, Takai Y, Zerial M (1993)
    Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins
    J Biol Chem, 268 (24), 18143-50
    PubMed 8349690
  19. van Deurs B, Holm PK, Kayser L, Sandvig K, Hansen SH (1993)
    Multivesicular bodies in HEp-2 cells are maturing endosomes
    Eur J Cell Biol, 61 (2), 208-24
    PubMed 8223712
  20. van Deurs B, Holm PK, Sandvig K, Hansen SH (1993)
    Are caveolae involved in clathrin-independent endocytosis?
    Trends Cell Biol, 3 (8), 249-51
    DOI 10.1016/0962-8924(93)90045-3, PubMed 14731741
  21. Zerial M, Stenmark H (1993)
    Rab GTPases in vesicular transport
    Curr Opin Cell Biol, 5 (4), 613-20
    DOI 10.1016/0955-0674(93)90130-i, PubMed 8257602

Publications 1992

  1. Falnes PO, Madshus IH, Sandvig K, Olsnes S (1992)
    Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels
    J Biol Chem, 267 (17), 12284-90
    PubMed 1376320
  2. Hansen SH, Sandvig K, van Deurs B (1992)
    Internalization efficiency of the transferrin receptor
    Exp Cell Res, 199 (1), 19-28
    DOI 10.1016/0014-4827(92)90457-j, PubMed 1735458
  3. Jonas L, Walzel H, Bremer H, Wiedlocha A (1992)
    Comparative studies on internalization of gold labelled mistletoe lectin I (MLI), its subunits, and of an immunotoxin into mouse L 1210V leukemia cells
    Acta Histochem, 92 (1), 46-53
    DOI 10.1016/S0065-1281(11)80140-6, PubMed 1580141
  4. Madshus IH, Olsnes S, Stenmark H (1992)
    Membrane translocation of diphtheria toxin carrying passenger protein domains
    Infect Immun, 60 (8), 3296-302
    DOI 10.1128/iai.60.8.3296-3302.1992, PubMed 1639497
  5. Madshus IH, Stenmark H (1992)
    Entry of ADP-ribosylating toxins into cells
    Curr Top Microbiol Immunol, 175, 1-26
    DOI 10.1007/978-3-642-76966-5_1, PubMed 1378368
  6. O'Brien AD, Tesh VL, Donohue-Rolfe A, Jackson MP, Olsnes S, Sandvig K, Lindberg AA, Keusch GT (1992)
    Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis
    Curr Top Microbiol Immunol, 180, 65-94
    DOI 10.1007/978-3-642-77238-2_4, PubMed 1324134
  7. Olsnes S, Frankel AE (1992)
    Genetically engineered toxins in perspective
    Targeted Diagn Ther, 7, 465-77
    PubMed 1633307
  8. Paprocka M, Wiedłocha A, Walzel H, Radzikowski C (1992)
    The activity of two immunotoxins composed of monoclonal antibody MoAb-16 and A-chain of ricin (MoAb-16-RTA) or A-chain of mistletoe lectin I (MoAb-16-MLIA)
    Arch Immunol Ther Exp (Warsz), 40 (3-4), 223-7
    PubMed 1300987
  9. Prydz K, Hansen SH, Sandvig K, van Deurs B (1992)
    Effects of brefeldin A on endocytosis, transcytosis and transport to the Golgi complex in polarized MDCK cells
    J Cell Biol, 119 (2), 259-72
    DOI 10.1083/jcb.119.2.259, PubMed 1400572
  10. Sandvig K, Dubinina E, Garred O, Prydz K, Kozlov JV, Hansen SH, van Deurs B (1992)
    Protein toxins: mode of action and cell entry
    Biochem Soc Trans, 20 (4), 724-7
    DOI 10.1042/bst0200724, PubMed 1487049
  11. Sandvig K, Garred O, Prydz K, Kozlov JV, Hansen SH, van Deurs B (1992)
    Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum
    Nature, 358 (6386), 510-2
    DOI 10.1038/358510a0, PubMed 1641040
  12. Sandvig K, van Deurs B (1992)
    Toxin-induced cell lysis: protection by 3-methyladenine and cycloheximide
    Exp Cell Res, 200 (2), 253-62
    DOI 10.1016/0014-4827(92)90171-4, PubMed 1572394
  13. Stenmark H, Afanasiev BN, Ariansen S, Olsnes S (1992)
    Association between diphtheria toxin A- and B-fragment and their fusion proteins
    Biochem J, 281 ( Pt 3) (Pt 3), 619-25
    DOI 10.1042/bj2810619, PubMed 1536643
  14. Stenmark H, Ariansen S, Afanasiev BN, Olsnes S (1992)
    Interactions of diphtheria toxin B-fragment with cells. Role of amino- and carboxyl-terminal regions
    J Biol Chem, 267 (13), 8957-62
    PubMed 1374382
  15. Wiedlocha A, Madshus IH, Mach H, Middaugh CR, Olsnes S (1992)
    Tight folding of acidic fibroblast growth factor prevents its translocation to the cytosol with diphtheria toxin as vector
    EMBO J, 11 (13), 4835-42
    DOI 10.1002/j.1460-2075.1992.tb05589.x, PubMed 1281450

Publications 1991

  1. Erikstein BK, Smeland EB, Blomhoff HK, Funderud S, Prydz K, Lesslauer W, Espevik T (1991)
    Independent regulation of 55-kDa and 75-kDa tumor necrosis factor receptors during activation of human peripheral blood B lymphocytes
    Eur J Immunol, 21 (4), 1033-7
    DOI 10.1002/eji.1830210426, PubMed 1850359
  2. Hansen SH, Sandvig K, van Deurs B (1991)
    The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations
    J Cell Biol, 113 (4), 731-41
    DOI 10.1083/jcb.113.4.731, PubMed 1673969
  3. Jacobsen AB, Tveit KM, Pettersen EO, Fossa SD, Ous S (1991)
    Colony formation in urinary bladder carcinoma. Relationship to DNA flow cytometry, stage and histopathology
    Anticancer Res, 11 (2), 777-81
    PubMed 2064333
  4. Kjønniksen I, Høifødt HK, Pihl A, Fodstad O (1991)
    Different metastasis patterns of a human melanoma cell line in nude mice and rats: influence of microenvironment
    J Natl Cancer Inst, 83 (14), 1020-4
    DOI 10.1093/jnci/83.14.1020, PubMed 2072409
  5. Ludt J, Tønnessen TI, Sandvig K, Olsnes S (1991)
    Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport
    J Membr Biol, 119 (2), 179-86
    DOI 10.1007/BF01871417, PubMed 2046087
  6. Madshus IH, Stenmark H, Sandvig K, Olsnes S (1991)
    Entry of diphtheria toxin-protein A chimeras into cells
    J Biol Chem, 266 (26), 17446-53
    PubMed 1894632
  7. Melby EL, Prydz K, Olsnes S, Sandvig K (1991)
    Effect of monensin on ricin and fluid phase transport in polarized MDCK cells
    J Cell Biochem, 47 (3), 251-60
    DOI 10.1002/jcb.240470311, PubMed 1791187
  8. Moskaug JO, Stenmark H, Olsnes S (1991)
    Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions
    J Biol Chem, 266 (4), 2652-9
    PubMed 1990012
  9. Nesland JM, Ottestad L, Heikilla R, Holm R, Tveit K, Børresen AL (1991)
    C-erbB-2 protein and neuroendocrine expression in breast carcinomas
    Anticancer Res, 11 (1), 161-7
    PubMed 1673329
  10. Olsnes S, Kozlov JV, van Deurs B, Sandvig K (1991)
    Bacterial protein toxins acting on intracellular targets
    Semin Cell Biol, 2 (1), 7-14
    PubMed 1954345
  11. Sandvig K, Prydz K, Hansen SH, van Deurs B (1991)
    Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect
    J Cell Biol, 115 (4), 971-81
    DOI 10.1083/jcb.115.4.971, PubMed 1955466
  12. Sandvig K, Prydz K, Ryd M, van Deurs B (1991)
    Endocytosis and intracellular transport of the glycolipid-binding ligand Shiga toxin in polarized MDCK cells
    J Cell Biol, 113 (3), 553-62
    DOI 10.1083/jcb.113.3.553, PubMed 1901867
  13. Sandvig K, van Deurs B (1991)
    Endocytosis without clathrin (a minireview)
    Cell Biol Int Rep, 15 (1), 3-8
    DOI 10.1016/0309-1651(91)90077-v, PubMed 1900741
  14. Stenmark H, Moskaug JO, Madshus IH, Sandvig K, Olsnes S (1991)
    Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
    J Cell Biol, 113 (5), 1025-32
    DOI 10.1083/jcb.113.5.1025, PubMed 2040642
  15. Stenmark H, Olsnes S, Madshus IH (1991)
    Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding
    Mol Microbiol, 5 (3), 595-606
    DOI 10.1111/j.1365-2958.1991.tb00730.x, PubMed 1646374
  16. Storeng RT, Kjønniksen I, Pihl A, Haug E, Fodstad O (1991)
    Athymic rats in preclinical immunodiagnostic studies
    Anticancer Res, 11 (2), 649-55
    PubMed 2064318
  17. Wiedłocha A, Sandvig K, Walzel H, Radzikowsky C, Olsnes S (1991)
    Internalization and action of an immunotoxin containing mistletoe lectin A-chain
    Cancer Res, 51 (3), 916-20
    PubMed 1988131

Publications 1990

  1. Børresen AL, Ottestad L, Gaustad A, Andersen TI, Heikkilä R, Jahnsen T, Tveit KM, Nesland JM (1990)
    Amplification and protein over-expression of the neu/HER-2/c-erbB-2 protooncogene in human breast carcinomas: relationship to loss of gene sequences on chromosome 17, family history and prognosis
    Br J Cancer, 62 (4), 585-90
    DOI 10.1038/bjc.1990.334, PubMed 1977466
  2. Kjønniksen I, Nesland JM, Pihl A, Fodstad O (1990)
    Nude rat model for studying metastasis of human tumor cells to bone and bone marrow
    J Natl Cancer Inst, 82 (5), 408-12
    DOI 10.1093/jnci/82.5.408, PubMed 2304088
  3. Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1990)
    Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
    J Physiol (Paris), 84 (3), 191-6
    PubMed 1705980
  4. Olsnes S, Stenmark H, Moskaug JO, McGill S, Madshus IH, Sandvig K (1990)
    Protein toxins with intracellular targets
    Microb Pathog, 8 (3), 163-8
    DOI 10.1016/0882-4010(90)90043-p, PubMed 1696341
  5. Paprocka M, Wiedlocha A, Radzikowski C (1990)
    Mouse L1210V leukemia as a model to analyse efficiency of leukemic cell elimination by immunotoxin, antibody and complement, and cytostatic agents
    In Vivo, 4 (3), 209-13
    PubMed 2133264
  6. Sandvig K, van Deurs B (1990)
    Selective modulation of the endocytic uptake of ricin and fluid phase markers without alteration in transferrin endocytosis
    J Biol Chem, 265 (11), 6382-8
    PubMed 1969411
  7. Tønnessen TI, Sandvig K, Olsnes S (1990)
    Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality
    Am J Physiol, 258 (6 Pt 1), C1117-26
    DOI 10.1152/ajpcell.1990.258.6.C1117, PubMed 2163200
  8. Tønnessen TI, Aas AT, Ludt J, Blomhoff HK, Olsnes S (1990)
    Regulation of Na+/H+ and Cl-/HCO3- antiports in Vero cells
    J Cell Physiol, 143 (1), 178-87
    DOI 10.1002/jcp.1041430125, PubMed 2156872
  9. van Deurs B, Hansen SH, Petersen OW, Melby EL, Sandvig K (1990)
    Endocytosis, intracellular transport and transcytosis of the toxic protein ricin by a polarized epithelium
    Eur J Cell Biol, 51 (1), 96-109
    PubMed 2328741

Publications 1989

  1. Eker P (1989)
    Effects of epidermal growth factor, fibroblast growth factor, retinoic acid and serum on anchorage-dependent and anchorage-independent growth of HRRT cells
    Eur J Cancer Clin Oncol, 25 (3), 499-504
    DOI 10.1016/0277-5379(89)90263-0, PubMed 2784762
  2. Hansen SH, Petersen OW, Sandvig K, Olsnes S, van Deurs B (1989)
    Internalized ricin and the plasma membrane glycoprotein MAM-6 colocalize in the trans-Golgi network of T47D human breast carcinoma cells
    Exp Cell Res, 185 (2), 373-86
    DOI 10.1016/0014-4827(89)90307-8, PubMed 2689197
  3. Katnik I, Steuden I, Pupek M, Wiedłocha A, Dobryszycka W (1989)
    Monoclonal antibodies against human haptoglobin
    Hybridoma, 8 (5), 551-60
    DOI 10.1089/hyb.1989.8.551, PubMed 2478448
  4. Kjønniksen I, Storeng R, Pihl A, McLemore TL, Fodstad O (1989)
    A human tumor lung metastasis model in athymic nude rats
    Cancer Res, 49 (18), 5148-52
    PubMed 2766284
  5. KOTANSKA KM, HOLM R, OTTESTAD L, NESLAND JM (1989)
    AN ULTRASTRUCTURAL-STUDY OF BENIGN AND MALIGNANT BREAST EPITHELIAL-CELLS - A SEARCH FOR TONOFILAMENTS
    J. Submicrosc. Cytol. Pathol., 21 (3), 469-474
  6. McGill S, Stenmark H, Sandvig K, Olsnes S (1989)
    Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants
    EMBO J, 8 (10), 2843-8
    DOI 10.1002/j.1460-2075.1989.tb08431.x, PubMed 2684631
  7. Moskaug JO, Sandvig K, Olsnes S (1989)
    Role of anions in low pH-induced translocation of diphtheria toxin
    J Biol Chem, 264 (19), 11367-72
    PubMed 2500440
  8. Moskaug JO, Sletten K, Sandvig K, Olsnes S (1989)
    Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage
    J Biol Chem, 264 (26), 15709-13
    PubMed 2768283
  9. Nenseter MS, Myklebost O, Blomhoff R, Drevon CA, Nilsson A, Norum KR, Berg T (1989)
    Low-density-lipoprotein receptors in different rabbit liver cells
    Biochem J, 261 (2), 587-93
    DOI 10.1042/bj2610587, PubMed 2549976
  10. Olsnes S, Sandvig K, Petersen OW, van Deurs B (1989)
    Immunotoxins--entry into cells and mechanisms of action
    Immunol Today, 10 (9), 291-5
    PubMed 2686677
  11. Olsnes S, Stenmark H, McGill S, Hovig E, Collier RJ, Sandvig K (1989)
    Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
    J Biol Chem, 264 (22), 12747-51
    PubMed 2753882
  12. OLSNES S, STENMARK H, MCGILL S, HOVIG E, COLLIER RJ, SANDVIG K (1989)
    FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
    J. Biol. Chem., 264 (22), 12749-12751
  13. Ottestad L, Tveit KM, Hannisdal E, Skrede M, Nesland JM, Gundersen S, Pihl A (1989)
    Colony forming ability of human breast carcinomas: lack of prognostic significance
    Br J Cancer, 60 (2), 216-9
    DOI 10.1038/bjc.1989.254, PubMed 2765368
  14. Radzikowski CZ, Steuden I, Wiedlocha A, Kieler J, Tromholt V (1989)
    The Thomsen-Friedenreich antigen on human urothelial cell lines detectable by peanut lectin and monoclonal antibody raised against human glycophorin A
    Anticancer Res, 9 (1), 103-7
    PubMed 2650614
  15. Sandvig K, Olsnes S, Brown JE, Petersen OW, van Deurs B (1989)
    Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1
    J Cell Biol, 108 (4), 1331-43
    DOI 10.1083/jcb.108.4.1331, PubMed 2564398
  16. Sandvig K, Olsnes S, Petersen OW, Van Deurs B (1989)
    Control of coated-pit function by cytoplasmic pH
    Methods Cell Biol, 32, 365-82
    DOI 10.1016/s0091-679x(08)61181-4, PubMed 2575206
  17. Stenmark H, McGill S, Olsnes S, Sandvig K (1989)
    Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
    EMBO J, 8 (10), 2849-53
    DOI 10.1002/j.1460-2075.1989.tb08432.x, PubMed 2479538
  18. Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
    Inhibition of chloride/bicarbonate antiports in monkey kidney cells (Vero) by non-steroidal anti-inflammatory drugs
    Biochem Pharmacol, 38 (20), 3583-91
    DOI 10.1016/0006-2952(89)90131-7, PubMed 2818647
  19. Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
    Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport
    J Pharmacol Exp Ther, 248 (3), 1197-206
    PubMed 2703970
  20. van Deurs B, Petersen OW, Olsnes S, Sandvig K (1989)
    The ways of endocytosis
    Int Rev Cytol, 117, 131-77
    DOI 10.1016/s0074-7696(08)61336-4, PubMed 2573583
  21. van Deurs B, Petersen OW, Sandvig K, Olsnes S (1989)
    [Endocytosis, intracellular transport and sorting of proteins]
    Nord Med, 104 (1), 9-11
    PubMed 2911460

Publications 1988

  1. Bruland OS, Fodstad O, Stenwig AE, Pihl A (1988)
    Expression and characteristics of a novel human osteosarcoma-associated cell surface antigen
    Cancer Res, 48 (18), 5302-9
    PubMed 2457439
  2. Czerwiński M, Waśniowska K, Steuden I, Duk M, Wiedłocha A, Lisowska E (1988)
    Degradation of the human erythrocyte membrane band 3 studied with monoclonal antibody directed against an epitope on the cytoplasmic fragment of band 3
    Eur J Biochem, 174 (4), 647-54
    DOI 10.1111/j.1432-1033.1988.tb14147.x, PubMed 2455637
  3. Erikstein B, Nesland JM, Ottestad L, Lund E, Johannessen JV (1988)
    Neuron specific enolase-positive breast carcinomas
    Histol Histopathol, 3 (1), 97-102
    PubMed 2980214
  4. Fodstad O, Kjønniksen I, Aamdal S, Nesland JM, Boyd MR, Pihl A (1988)
    Extrapulmonary, tissue-specific metastasis formation in nude mice injected with FEMX-I human melanoma cells
    Cancer Res, 48 (15), 4382-8
    PubMed 3390834
  5. Herz J, Hamann U, Rogne S, Myklebost O, Gausepohl H, Stanley KK (1988)
    Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor
    EMBO J, 7 (13), 4119-27
    DOI 10.1002/j.1460-2075.1988.tb03306.x, PubMed 3266596
  6. Holtskog R, Sandvig K, Olsnes S (1988)
    Characterization of a toxic lectin in Iscador, a mistletoe preparation with alleged cancerostatic properties
    Oncology, 45 (3), 172-9
    DOI 10.1159/000226557, PubMed 3368193
  7. Madshus IH (1988)
    Regulation of intracellular pH in eukaryotic cells
    Biochem J, 250 (1), 1-8
    DOI 10.1042/bj2500001, PubMed 2965576
  8. Moskaug JO, Sandvig K, Olsnes S (1988)
    Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol
    J Biol Chem, 263 (5), 2518-25
    PubMed 3339019
  9. NESLAND JM, HOLM R, OTTESTAD L, KARLSEN KO, JOHANNESSEN JV (1988)
    NEURO-ENDOCRINE ACTIVITY IN METASTATIC BREAST CARCINOMAS
    APMIS, 96 2, 204-214
  10. Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1988)
    Diphtheria toxin entry: protein translocation in the reverse direction
    Trends Biochem Sci, 13 (9), 348-51
    DOI 10.1016/0968-0004(88)90105-3, PubMed 3072713
  11. Olsnes S, Sandvig K (1988)
    How protein toxins enter and kill cells
    Cancer Treat Res, 37, 39-73
    DOI 10.1007/978-1-4613-1083-9_4, PubMed 2908634
  12. Ottestad L, Tveit KM, Høifødt HK, Nesland JM, Vaage S, Høie J, Lund E, Pihl A (1988)
    Cultivation of human breast carcinoma in soft agar. Experience with 237 fresh tumour specimens
    Br J Cancer, 58 (1), 8-12
    DOI 10.1038/bjc.1988.151, PubMed 3048354
  13. Ottestad LO, Tveit KM, Nesland JM, Dybsjord I, Børmer O, Høie J, Pihl A (1988)
    An immunocytochemical method for assaying oestrogen receptors in breast cancers. A comparison with the steroid binding assay
    Histol Histopathol, 3 (3), 269-74
    PubMed 2980233
  14. Reinertsen KV, Tønnessen TI, Jacobsen J, Sandvig K, Olsnes S (1988)
    Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport
    J Biol Chem, 263 (23), 11117-25
    PubMed 3403517
  15. Sandvig K, Olsnes S (1988)
    Diphtheria toxin-induced channels in Vero cells selective for monovalent cations
    J Biol Chem, 263 (25), 12352-9
    PubMed 2457582
  16. Sandvig K, Olsnes S, Petersen OW, van Deurs B (1988)
    Inhibition of endocytosis from coated pits by acidification of the cytosol
    J Cell Biochem, 36 (1), 73-81
    DOI 10.1002/jcb.240360108, PubMed 2893802
  17. Stenmark H, Olsnes S, Sandvig K (1988)
    Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
    J Biol Chem, 263 (26), 13449-55
    PubMed 3417666
  18. van Deurs B, Sandvig K, Petersen OW, Olsnes S, Simons K, Griffiths G (1988)
    Estimation of the amount of internalized ricin that reaches the trans-Golgi network
    J Cell Biol, 106 (2), 253-67
    DOI 10.1083/jcb.106.2.253, PubMed 2892843
  19. Waśniowska K, Duk M, Steuden I, Czerwiński M, Wiedłocha A, Lisowska E (1988)
    Two monoclonal antibodies recognizing different epitopes of blood group N antigen
    Arch Immunol Ther Exp (Warsz), 36 (5), 623-32
    PubMed 2478103

Publications 1987

  1. Bruland O, Fodstad O, Skretting A, Pihl A (1987)
    Selective localisation of two radiolabelled anti-sarcoma monoclonal antibodies in human osteosarcoma xenografts
    Br J Cancer, 56 (1), 21-5
    DOI 10.1038/bjc.1987.146, PubMed 3476143
  2. Godal A, Fodstad O, Pihl A (1987)
    Studies on the mechanism of action of abrin-9.2.27 immunotoxin in human melanoma cell lines
    Cancer Res, 47 (23), 6243-7
    PubMed 2445469
  3. Gundersen S, Aamdal S, Fodstad O (1987)
    Mitozolomide (NSC 353451), a new active drug in the treatment of malignant melanoma. Phase II trial in patients with advanced disease
    Br J Cancer, 55 (4), 433-5
    DOI 10.1038/bjc.1987.85, PubMed 3580266
  4. Hovig E, Winberg JO, Fodstad O, Brøgger A, Gedde-Dahl T (1987)
    Chromosome 13 instability and esterase D expression in an osteosarcoma cell line
    Cancer Genet Cytogenet, 24 (2), 327-34
    DOI 10.1016/0165-4608(87)90115-4, PubMed 2878716
  5. Madshus IH, Olsnes S (1987)
    Selective inhibition of sodium-linked and sodium-independent bicarbonate/chloride antiport in Vero cells
    J Biol Chem, 262 (16), 7486-91
    PubMed 3584123
  6. Madshus IH, Sandvig K, Olsnes S, van Deurs B (1987)
    Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses
    J Cell Physiol, 131 (1), 14-22
    DOI 10.1002/jcp.1041310104, PubMed 3032992
  7. Madshus IH, Tønnessen TI, Olsnes S, Sandvig K (1987)
    Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
    J Cell Physiol, 131 (1), 6-13
    DOI 10.1002/jcp.1041310103, PubMed 3571337
  8. Moskaug JO, Sandvig K, Olsnes S (1987)
    Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH
    J Biol Chem, 262 (21), 10339-45
    PubMed 3112141
  9. Olsnes S (1987)
    Closing in on ricin action
    Nature, 328 (6130), 474-5
    DOI 10.1038/328474b0, PubMed 3614350
  10. Olsnes S, Ludt J, Tønnessen TI, Sandvig K (1987)
    Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
    J Cell Physiol, 132 (2), 192-202
    DOI 10.1002/jcp.1041320203, PubMed 3624315
  11. Olsnes S, Tønnessen TI, Ludt J, Sandvig K (1987)
    Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
    Biochemistry, 26 (10), 2778-85
    DOI 10.1021/bi00384a019, PubMed 3606992
  12. Sandvig K, Brown JE (1987)
    Ionic requirements for entry of Shiga toxin from Shigella dysenteriae 1 into cells
    Infect Immun, 55 (2), 298-303
    DOI 10.1128/iai.55.2.298-303.1987, PubMed 3542829
  13. Sandvig K, Moskaug JO (1987)
    Pseudomonas toxin binds triton X-114 at low pH
    Biochem J, 245 (3), 899-901
    DOI 10.1042/bj2450899, PubMed 3117052
  14. Sandvig K, Olsnes S, Petersen OW, van Deurs B (1987)
    Acidification of the cytosol inhibits endocytosis from coated pits
    J Cell Biol, 105 (2), 679-89
    DOI 10.1083/jcb.105.2.679, PubMed 2887575
  15. Tønnessen TI, Ludt J, Sandvig K, Olsnes S (1987)
    Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
    J Cell Physiol, 132 (2), 183-91
    DOI 10.1002/jcp.1041320202, PubMed 3624314
  16. van Deurs B, Petersen OW, Olsnes S, Sandvig K (1987)
    Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process
    Exp Cell Res, 171 (1), 137-52
    DOI 10.1016/0014-4827(87)90257-6, PubMed 3622628
  17. Aarnes CM, Madshus IH, Guillemot JC, Sandvig K, Olsnes S (1987)
    Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures
    Exp Cell Res, 170 (2), 483-90
    DOI 10.1016/0014-4827(87)90322-3, PubMed 3036553

Publications 1986

  1. Godal A, Bruland O, Haug E, Aas M, Fodstad O (1986)
    Unexpected expression of the 250 kD melanoma-associated antigen in human sarcoma cells
    Br J Cancer, 53 (6), 839-41
    DOI 10.1038/bjc.1986.142, PubMed 3718838
  2. Mustafa AS, Kvalheim G, Degre M, Godal T (1986)
    Mycobacterium bovis BCG-induced human T-cell clones from BCG-vaccinated healthy subjects: antigen specificity and lymphokine production
    Infect Immun, 53 (3), 491-7
    DOI 10.1128/iai.53.3.491-497.1986, PubMed 2427449
  3. Olsnes S, Carvajal E, Sandvig K (1986)
    Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate
    J Biol Chem, 261 (4), 1562-9
    PubMed 3632976
  4. Olsnes S, Sandvig K (1986)
    Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells
    J Biol Chem, 261 (4), 1542-52
    PubMed 3944100
  5. Olsnes S, Sandvig K (1986)
    Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin
    J Biol Chem, 261 (4), 1553-61
    PubMed 3944101
  6. Olsnes S, Tønnessen TI, Sandvig K (1986)
    pH-regulated anion antiport in nucleated mammalian cells
    J Cell Biol, 102 (3), 967-71
    DOI 10.1083/jcb.102.3.967, PubMed 3949885
  7. Sandvig K, Olsnes S (1986)
    Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport
    J Biol Chem, 261 (4), 1570-5
    PubMed 2418015
  8. SANDVIG K, TONNESSEN TI, SAND O, OLSNES S (1986)
    REQUIREMENT OF A TRANSMEMBRANE PH GRADIENT FOR THE ENTRY OF DIPHTHERIA-TOXIN INTO CELLS AT LOW PH
    J. Biol. Chem., 261 (25), 1639-1644
  9. Sandvig K, Tønnessen TI, Olsnes S (1986)
    Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
    Cancer Res, 46 (12 Pt 1), 6418-22
    PubMed 3096563
  10. Sandvig K, Tønnessen TI, Sand O, Olsnes S (1986)
    Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
    J Biol Chem, 261 (25), 11639-44
    PubMed 3745160
  11. van Deurs B, Tønnessen TI, Petersen OW, Sandvig K, Olsnes S (1986)
    Routing of internalized ricin and ricin conjugates to the Golgi complex
    J Cell Biol, 102 (1), 37-47
    DOI 10.1083/jcb.102.1.37, PubMed 3001103

Publications 1985

  1. Guillemot JC, Sundan A, Olsnes S, Sandvig K (1985)
    Entry of diphtheria toxin linked to concanavalin A into primate and murine cells
    J Cell Physiol, 122 (2), 193-9
    DOI 10.1002/jcp.1041220205, PubMed 3844014
  2. Madshus IH, Sandvig K, Olsnes S (1985)
    Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1
    Exp Cell Res, 160 (1), 240-4
    DOI 10.1016/0014-4827(85)90253-8, PubMed 2995095
  3. Olsnes S, Carvajal E, Sundan A, Sandvig K (1985)
    Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells
    Biochim Biophys Acta, 846 (3), 334-41
    DOI 10.1016/0167-4889(85)90003-5, PubMed 4041483
  4. Olsnes S, Sandvig K, Madshus IH, Sundan A (1985)
    Entry mechanisms of protein toxins and picornaviruses
    Biochem Soc Symp, 50, 171-91
    PubMed 3915869
  5. OLSNES S, SANDVIG K, MADSHUS IH, SUNDAN A (1985)
    ENTRY MECHANISMS OF PROTEIN TOXINS AND PICORNAVIRUSES
    Biochem. Soc. Symp. (50), 171-191
  6. Sandvig K, Olsnes S (1985)
    Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells
    Biochem J, 228 (2), 521-3
    DOI 10.1042/bj2280521, PubMed 2990449
  7. Sandvig K, Sundan A, Olsnes S (1985)
    Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin
    J Cell Physiol, 124 (1), 54-60
    DOI 10.1002/jcp.1041240110, PubMed 3930519
  8. Stirpe F, Barbieri L, Abbondanza A, Falasca AI, Brown AN, Sandvig K, Olsnes S, Pihl A (1985)
    Properties of volkensin, a toxic lectin from Adenia volkensii
    J Biol Chem, 260 (27), 14589-95
    PubMed 3932357
  9. STIRPE F, BARBIERI L, ABBONDANZA A, FALASCA AI, BROWN ANF, SANDVIG K, OLSNES S, PIHL A (1985)
    PROPERTIES OF VOLKENSIN, A TOXIC LECTIN FROM ADENIA-VOLKENSII
    J. Biol. Chem., 260 (27), 4589-4595
  10. van Deurs B, Pedersen LR, Sundan A, Olsnes S, Sandvig K (1985)
    Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing to vacuolar and tubulo-vesicular portions of the endosomal system
    Exp Cell Res, 159 (2), 287-304
    DOI 10.1016/s0014-4827(85)80003-3, PubMed 2863159
  11. Aamdal S, Fodstad O, Nesland JM, Pihl A (1985)
    Characteristics of human tumour xenografts transplanted under the renal capsule of immunocompetent mice
    Br J Cancer, 51 (3), 347-56
    DOI 10.1038/bjc.1985.46, PubMed 3970811

Publications 1984

  1. Ege T (1984)
    Analysis of heterokaryons and progeny cell hybrids isolated in the absence and in the presence of selective media
    Cell Biol Int Rep, 8 (7), 599-606
    DOI 10.1016/0309-1651(84)90060-2, PubMed 6744432
  2. Ege T (1984)
    Phenotypes of cell hybrids formed by fusion of normal and Rous sarcoma virus transformed cells
    Cell Biol Int Rep, 8 (7), 607-13
    DOI 10.1016/0309-1651(84)90061-4, PubMed 6086159
  3. Lindmo T, Davies C, Fodstad O, Morgan AC (1984)
    Stable quantitative differences of antigen expression in human melanoma cells isolated by flow cytometric cell sorting
    Int J Cancer, 34 (4), 507-12
    DOI 10.1002/ijc.2910340413, PubMed 6386700
  4. Lindmo T, Davies C, Rofstad EK, Fodstad O, Sundan A (1984)
    Antigen expression in human melanoma cells in relation to growth conditions and cell-cycle distribution
    Int J Cancer, 33 (2), 167-71
    DOI 10.1002/ijc.2910330203, PubMed 6693198
  5. Madshus IH, Olsnes S, Sandvig K (1984)
    Requirements for entry of poliovirus RNA into cells at low pH
    EMBO J, 3 (9), 1945-50
    DOI 10.1002/j.1460-2075.1984.tb02074.x, PubMed 6092049
  6. Madshus IH, Olsnes S, Sandvig K (1984)
    Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus
    Virology, 139 (2), 346-57
    DOI 10.1016/0042-6822(84)90380-5, PubMed 6097029
  7. Madshus IH, Olsnes S, Sandvig K (1984)
    Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH
    J Cell Biol, 98 (4), 1194-200
    DOI 10.1083/jcb.98.4.1194, PubMed 6325467
  8. Sandvig K, Madshus IH, Olsnes S (1984)
    Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus
    Biochem J, 219 (3), 935-40
    DOI 10.1042/bj2190935, PubMed 6331401
  9. Sandvig K, Olsnes S (1984)
    Receptor-mediated entry of protein toxins into cells
    Acta Histochem Suppl, 29, 79-94
    PubMed 6144140
  10. Sandvig K, Olsnes S (1984)
    Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin
    J Cell Physiol, 119 (1), 7-14
    DOI 10.1002/jcp.1041190103, PubMed 6707104
  11. Sandvig K, Sundan A, Olsnes S (1984)
    Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments
    J Cell Biol, 98 (3), 963-70
    DOI 10.1083/jcb.98.3.963, PubMed 6699094
  12. Sundan A, Sandvig K, Olsnes S (1984)
    Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin
    Cancer Res, 44 (11), 4919-23
    PubMed 6435858
  13. Sundan A, Sandvig K, Olsnes S (1984)
    Calmodulin antagonists sensitize cells to pseudomonas toxin
    J Cell Physiol, 119 (1), 15-22
    DOI 10.1002/jcp.1041190104, PubMed 6707099
  14. Wibe E, Berg JP, Tveit KM, Nesland JM, Lunde S (1984)
    Multicellular spheroids grown directly from human tumour material
    Int J Cancer, 34 (1), 21-6
    DOI 10.1002/ijc.2910340105, PubMed 6746116
  15. Aamdal S, Fodstad O, Kaalhus O, Pihl A (1984)
    Reduced antineoplastic activity in mice of cisplatin administered with high salt concentration in the vehicle
    J Natl Cancer Inst, 73 (3), 743-52
    PubMed 6590919

Publications 1983

  1. Eiklid K, Olsnes S (1983)
    Animal toxicity of Shigella dysenteriae cytotoxin: evidence that the neurotoxic, enterotoxic, and cytotoxic activities are due to one toxin
    J Immunol, 130 (1), 380-4
    PubMed 6336624
  2. Eiklid K, Olsnes S (1983)
    Entry of Shigella dysenteriae toxin into HeLa cells
    Infect Immun, 42 (2), 771-7
    DOI 10.1128/iai.42.2.771-777.1983, PubMed 6358031
  3. Sundan A, Sandvig K, Olsnes S (1983)
    Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase
    Biochem Biophys Res Commun, 117 (2), 562-7
    DOI 10.1016/0006-291x(83)91237-8, PubMed 6318763
  4. Sundan A, Sandvig K, Olsnes S (1983)
    Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain
    Biochim Biophys Acta, 761 (3), 296-302
    DOI 10.1016/0304-4165(83)90080-6, PubMed 6652111

Publications 1982

  1. Olsnes S, Haylett T, Sandvig K (1982)
    The toxic lectin modeccin
    Methods Enzymol, 83, 357-62
    DOI 10.1016/0076-6879(82)83030-9, PubMed 6178935
  2. Olsnes S, Stirpe F, Sandvig K, Pihl A (1982)
    Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe)
    J Biol Chem, 257 (22), 13263-70
    PubMed 7142144
  3. Sandvig K, Olsnes S (1982)
    Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
    J Biol Chem, 257 (13), 7495-503
    PubMed 6806276
  4. Sandvig K, Olsnes S (1982)
    Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
    J Biol Chem, 257 (13), 7504-13
    PubMed 7085634
  5. Stirpe F, Sandvig K, Olsnes S, Pihl A (1982)
    Action of viscumin, a toxic lectin from mistletoe, on cells in culture
    J Biol Chem, 257 (22), 13271-7
    PubMed 7142145
  6. Sundan A, Olsnes S, Sandvig K, Pihl A (1982)
    Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway
    J Biol Chem, 257 (16), 9733-9
    PubMed 7107588

Publications 1981

  1. Abraham AK, Vedeler A, Reistad R, Pihl A (1981)
    Polypeptide synthesis by mitoplasts isolated from mouse liver
    Exp Cell Res, 132 (2), 265-72
    DOI 10.1016/0014-4827(81)90102-6, PubMed 7215445
  2. Godal A, Olsnes S, Pihl A (1981)
    Radioimmunoassays of abrin and ricin in blood
    J Toxicol Environ Health, 8 (3), 409-17
    DOI 10.1080/15287398109530079, PubMed 7345165
  3. Olsnes S (1981)
    Directing toxins to cancer cells
    Nature, 290 (5802), 84
    DOI 10.1038/290084a0, PubMed 7207602
  4. Olsnes S, Pihl A (1981)
    Chimeric toxins
    Pharmacol Ther, 15 (3), 355-81
    DOI 10.1016/0163-7258(81)90050-4, PubMed 7345440
  5. Olsnes S, Reisbig R, Eiklid K (1981)
    Subunit structure of Shigella cytotoxin
    J Biol Chem, 256 (16), 8732-8
    PubMed 7021550
  6. Reisbig R, Olsnes S, Eiklid K (1981)
    The cytotoxic activity of Shigella toxin. Evidence for catalytic inactivation of the 60 S ribosomal subunit
    J Biol Chem, 256 (16), 8739-44
    PubMed 6894922
  7. Sandvig K, Olsnes S (1981)
    Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule
    J Biol Chem, 256 (17), 9068-76
    PubMed 7263699
  8. Sandvig K, Olsnes S (1981)
    Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin
    Biochem J, 194 (3), 821-7
    DOI 10.1042/bj1940821, PubMed 7306026

Publications 1980

  1. Eiklid K, Olsnes S (1980)
    Interaction of Shigella shigae cytotoxin with receptors on sensitive and insensitive cells
    J Recept Res, 1 (2), 199-213
    DOI 10.3109/10799898009044098, PubMed 6895387
  2. Eiklid K, Olsnes S, Pihl A (1980)
    Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells
    Exp Cell Res, 126 (2), 321-6
    DOI 10.1016/0014-4827(80)90270-0, PubMed 7363949
  3. Gonatas J, Stieber A, Olsnes S, Gonatas NK (1980)
    Pathways involved in fluid phase and adsorptive endocytosis in neuroblastoma
    J Cell Biol, 87 (3 Pt 1), 579-88
    DOI 10.1083/jcb.87.3.579, PubMed 7462317
  4. Olsnes S, Eiklid K (1980)
    Isolation and characterization of Shigella shigae cytotoxin
    J Biol Chem, 255 (1), 284-9
    PubMed 7350160
  5. Sandvig K (1980)
    [Receptors for polypeptide hormones]
    Tidsskr Nor Laegeforen, 100 (14), 964-6, 970
    PubMed 6250247
  6. Sandvig K (1980)
    [Intracellular mediators for polypeptide hormones]
    Tidsskr Nor Laegeforen, 100 (15), 1021-23
    PubMed 6250248
  7. Sandvig K, Olsnes S (1980)
    Diphtheria toxin entry into cells is facilitated by low pH
    J Cell Biol, 87 (3 Pt 1), 828-32
    DOI 10.1083/jcb.87.3.828, PubMed 7462324
  8. Stirpe F, Olsnes S, Pihl A (1980)
    Gelonin, a new inhibitor of protein synthesis, nontoxic to intact cells. Isolation, characterization, and preparation of cytotoxic complexes with concanavalin A
    J Biol Chem, 255 (14), 6947-53
    PubMed 7391060
  9. Tveit KM, Fodstad O, Brøgger A, Olsnes S (1980)
    Human embryonal carcinoma grown in athymic mice and in vitro
    Cancer Res, 40 (3), 949-53
    PubMed 7471109
  10. Tveit KM, Fodstad O, Johannessen JV, Olsnes S (1980)
    A human melanoma cell line established from xenograft in athymic mice
    Br J Cancer, 41 (5), 724-33
    DOI 10.1038/bjc.1980.134, PubMed 7426299
  11. Tveit KM, Fodstad O, Olsnes S, Pihl A (1980)
    In vitro sensitivity of human melanoma xenografts to cytotoxic drugs. Correlation with in vivo chemosensitivity
    Int J Cancer, 26 (6), 717-22
    DOI 10.1002/ijc.2910260604, PubMed 7216540

Publications 1979

  1. Abraham AK, Olsnes S, Pihl A (1979)
    Fidelity of protein synthesis in vitro is increased in the presence of spermidine
    FEBS Lett, 101 (1), 93-6
    DOI 10.1016/0014-5793(79)81302-2, PubMed 446744
  2. Olsnes S, Abraham AK (1979)
    Elongation-factor-2-induced sensitization of ribosomes to modeccin. Evidence for specific binding of elongation factor 2 to ribosomes in the absence of nucleotides
    Eur J Biochem, 93 (3), 447-52
    DOI 10.1111/j.1432-1033.1979.tb12842.x, PubMed 421687
  3. Sandvig K, Olsnes S (1979)
    Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells
    Exp Cell Res, 121 (1), 15-25
    DOI 10.1016/0014-4827(79)90439-7, PubMed 446525
  4. Sandvig K, Olsnes S, Pihl A (1979)
    Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells
    Biochem Biophys Res Commun, 90 (2), 648-55
    DOI 10.1016/0006-291x(79)91284-1, PubMed 508328

Publications 1978

  1. Olsnes S (1978)
    Toxic and nontoxic lectins from Abrus precatorius
    Methods Enzymol, 50, 323-30
    DOI 10.1016/0076-6879(78)50036-0, PubMed 661585
  2. Olsnes S (1978)
    Ricin and ricinus agglutinin, toxic lectins from castor bean
    Methods Enzymol, 50, 330-5
    DOI 10.1016/0076-6879(78)50037-2, PubMed 661586
  3. Olsnes S, Haylett T, Refsnes K (1978)
    Purification and characterization of the highly toxic lectin modeccin
    J Biol Chem, 253 (14), 5069-73
    PubMed 97288
  4. OLSNES S, PIHL A (1978)
    ABRIN AND RICIN-2 TOXIC LECTINS
    Trends Biochem.Sci., 3 (1), 7-10
    DOI 10.1016/S0968-0004(78)92494-5
  5. Olsnes S, Refsnes K (1978)
    On the mechanism of toxin resistance in cell variants resistant to abrin and ricin
    Eur J Biochem, 88 (1), 7-15
    DOI 10.1111/j.1432-1033.1978.tb12417.x, PubMed 566668
  6. Olsnes S, Sandvig K, Eiklid K, Pihl A (1978)
    Properties and action mechanism of the toxic lectin modeccin: interaction with cell lines resistant to modeccin, abrin, and ricin
    J Supramol Struct, 9 (1), 15-25
    DOI 10.1002/jss.400090103, PubMed 732310
  7. Olsnes S, Tveit KM (1978)
    [Teratocarcinoma as a model system in studies of malignancy and differentiation]
    Tidsskr Nor Laegeforen, 98 (22), 998-1001
    PubMed 684708
  8. Sandvig K (1978)
    Cell density affects the binding of the toxic lectin abrin to HeLa cells in monolayer cultures
    FEBS Lett, 89 (2), 233-6
    DOI 10.1016/0014-5793(78)80225-7, PubMed 658411
  9. Sandvig K, Olsnes S, Pihl A (1978)
    Interactions between abrus lectins and Sephadex particles possessing immobilized desialylated fetuin. Model studies of the interaction of lectins with cell surface receptors
    Eur J Biochem, 88 (1), 307-13
    DOI 10.1111/j.1432-1033.1978.tb12451.x, PubMed 78847
  10. Sandvig K, Olsnes S, Pihl A (1978)
    Binding, uptake and degradation of the toxic proteins abrin and ricin by toxin-resistant cell variants
    Eur J Biochem, 82 (1), 13-23
    DOI 10.1111/j.1432-1033.1978.tb11992.x, PubMed 620666
  11. Sandvig K, Olsnes S, Pihl A (1978)
    Chemical modifications of the toxic lectins abrin and ricin
    Eur J Biochem, 84 (2), 323-31
    DOI 10.1111/j.1432-1033.1978.tb12171.x, PubMed 639792
  12. Wibe E, Oftebro R, Christensen T, Laland SG, Pettersen EO, Lindmo T (1978)
    Inhibitory effects of the new mitotic inhibitor 5-chloropyrimidin-2-one and of vincristine on human cells in vitro
    Cancer Res, 38 (3), 560-5
    PubMed 626961

Publications 1977

  1. Benson SC (1977)
    Correlation of inhibition of ribosomal GTPase and protein synthesis by abrin and ricin
    Biochem Biophys Res Commun, 75 (4), 845-50
    DOI 10.1016/0006-291x(77)91459-0, PubMed 193503
  2. Fodstad O, Olsnes S (1977)
    Studies on the accessability of ribosomes to inactivation by the toxic lectins abrin and ricin
    Eur J Biochem, 74 (2), 209-15
    DOI 10.1111/j.1432-1033.1977.tb11383.x, PubMed 856578
  3. Fodstad O, Olsnes S, Pihl A (1977)
    Inhibitory effect of abrin and ricin on the growth of transplantable murine tumors and of abrin on human cancers in nude mice
    Cancer Res, 37 (12), 4559-67
    PubMed 922739
  4. Refsnes K, Haylett T, Sandvig K, Olsnes S (1977)
    Modeccin--a plant toxin inhibiting protein synthesis
    Biochem Biophys Res Commun, 79 (4), 1176-83
    DOI 10.1016/0006-291x(77)91130-5, PubMed 603653
  5. Skorve J, Abraham AK, Olsnes S, Pihl A (1977)
    Effect of abrin on peptide chain initiation
    Eur J Biochem, 79 (2), 559-64
    DOI 10.1111/j.1432-1033.1977.tb11840.x, PubMed 243461

Publications 1976

  1. Fernandez-Puentes C, Benson S, Olsnes S, Pihl A (1976)
    Protective effect of elongation factor 2 on the inactivation of ribosomes by the toxic lectins abrin and ricin
    Eur J Biochem, 64 (2), 437-43
    DOI 10.1111/j.1432-1033.1976.tb10320.x, PubMed 1278169
  2. Fodstad O, Olsnes S, Pihl A (1976)
    Toxicity, distribution and elimination of the cancerostatic lectins abrin and ricin after parenteral injection into mice
    Br J Cancer, 34 (4), 418-25
    DOI 10.1038/bjc.1976.187, PubMed 974006
  3. OLSNES S (1976)
    ABRIN AND RICIN - STRUCTURE AND MECHANISM OF ACTION OF 2 TOXIC LECTINS
    Bull. Inst. Pasteur, 74 (1), 85-99
  4. Olsnes S, Sandvig K, Refsnes K, Pihl A (1976)
    Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin
    J Biol Chem, 251 (13), 3985-92
    PubMed 932017
  5. Sandvig K, Olsnes S, Pihl A (1976)
    Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells
    J Biol Chem, 251 (13), 3977-84
    PubMed 6468

Publications 1975

  1. Benson S, Olsnes S, Pihl A, Skorve J, Abraham AK (1975)
    On the mechanism of protein-synthesis inhibition by abrin and ricin. Inhibition of the GTP-hydrolysis site on the 60-S ribosomal subunit
    Eur J Biochem, 59 (2), 573-80
    DOI 10.1111/j.1432-1033.1975.tb02484.x, PubMed 128455
  2. Closs O, Saltvedt E, Olsnes S (1975)
    Stimulation of human lymphocytes by galactose-specific abrus and ricinus lectins
    J Immunol, 115 (4), 1045-8
    PubMed 1176765
  3. HARBOE M, SALTVEDT E, CLOSS O, OLSNES S (1975)
    INTERACTIONS BETWEEN RICINUS AGGLUTININ AND HUMAN PLASMA-PROTEINS
    Scand. J. Immunol. (2), 125-134
  4. Kozlov JV, Olsnes S, Brogger A, Pihl A (1975)
    Cleavage of adenovirus-5 DNA by an endonuclease from Haemophilus parainfluenzae
    FEBS Lett, 57 (2), 153-7
    DOI 10.1016/0014-5793(75)80705-8, PubMed 1175785
  5. Olsnes S, Fernandez-Puentes C, Carrasco L, Vazquez D (1975)
    Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains
    Eur J Biochem, 60 (1), 281-8
    DOI 10.1111/j.1432-1033.1975.tb21001.x, PubMed 1204642
  6. Olsnes S, Refsnes K, Christensen TB, Pihl A (1975)
    Studies on the structure and properties of the lectins from Abrus precatorius and Ricinus communis
    Biochim Biophys Acta, 405 (1), 1-10
    DOI 10.1016/0005-2795(75)90308-6, PubMed 1174560
  7. Olsnes S, Saltvedt E (1975)
    Conformation-dependent antigenic determinants in the toxic lectin ricin
    J Immunol, 114 (6), 1743-8
    PubMed 47877
  8. Saltvedt E, Harboe M, Følling I, Olsnes S (1975)
    Interactions between ricinus agglutinin and human IgM and IgG
    Scand J Immunol, 4 (3), 287-94
    DOI 10.1111/j.1365-3083.1975.tb02628.x, PubMed 1080291

Publications 1974

  1. Olsnes S, Pappenheimer AM, Meren R (1974)
    Lectins from Abrus precatorius and Ricinus communis. II. Hybrid toxins and their interaction with chain-specific antibodies
    J Immunol, 113 (3), 842-7
    PubMed 4414071
  2. Olsnes S, Pihl A (1974)
    Clinical significance of estrogen receptors in human breast cancer
    Biomedicine, 20 (6), 377-83
    PubMed 4376029
  3. Olsnes S, Refsnes K, Pihl A (1974)
    Mechanism of action of the toxic lectins abrin and ricin
    Nature, 249 (458), 627-31
    DOI 10.1038/249627a0, PubMed 4857870
  4. Olsnes S, Saltvedt E, Pihl A (1974)
    Isolation and comparison of galactose-binding lectins from Abrus precatorius and Ricinus communis
    J Biol Chem, 249 (3), 803-10
    PubMed 4811904
  5. Pappenheimer AM, Olsnes S, Harper AA (1974)
    Lectins from Abrus precatorius and Ricinus communis. I. Immunochemical relationships between toxins and agglutinins
    J Immunol, 113 (3), 835-41
    PubMed 4213214
  6. Refsnes K, Olsnes S, Pihl A (1974)
    On the toxic proteins abrin and ricin. Studies of their binding to and entry into Ehrlich ascites cells
    J Biol Chem, 249 (11), 3557-62
    PubMed 4208663
  7. REFSNES K, OLSNES S, PIHL A (1974)
    TOXIC PROTEINS ABRIN AND RICIN - STUDIES OF THEIR BINDING TO AND ENTRY INTO EHRLICH ASCITES-CELLS
    J. Biol. Chem., 249 (11), 3557-3562

Publications 1973

  1. Olsnes S (1973)
    [Gene activation and mRNA synthesis in higher organisms]
    Tidsskr Nor Laegeforen, 93 (16), 1230-5
    PubMed 4356591
  2. Olsnes S (1973)
    [Diphtheria toxin--a specific inhibitor of protein synthesis]
    Tidsskr Nor Laegeforen, 93 (4), 223-7
    PubMed 4691026
  3. Olsnes S, Heiberg R, Pihl A (1973)
    Inactivation of eucaryotic ribosomes by the toxic plant proteins abrin and ricin
    Mol Biol Rep, 1 (1), 15-20
    DOI 10.1007/BF00357400, PubMed 24197425
  4. Olsnes S, Pihl A (1973)
    Isolation and properties of abrin: a toxic protein inhibiting protein synthesis. Evidence for different biological functions of its two constituent-peptide chains
    Eur J Biochem, 35 (1), 179-85
    DOI 10.1111/j.1432-1033.1973.tb02823.x, PubMed 4123356
  5. Olsnes S, Pihl A (1973)
    Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis
    Biochemistry, 12 (16), 3121-6
    DOI 10.1021/bi00740a028, PubMed 4730499
  6. Spaeren U, Olsnes S, Brennhovd I, Efskind J, Pihl A (1973)
    Content of estrogen receptors in human breast cancer
    Eur J Cancer (1965), 9 (5), 353-7
    DOI 10.1016/0014-2964(73)90050-9, PubMed 4355726

Publications 1972

  1. Birkeland H, Bottolfsen K (1972)
    [Iridocyclitis with juvenile rheumatoid arthritis]
    Tidsskr Nor Laegeforen, 12 (13), 922-3
    PubMed 5063957
  2. Heiberg R, Spaeren U, Olsnes S, Pihl A (1972)
    Binding of rat liver ribosomes to nuclear complementary RNA
    Biochim Biophys Acta, 281 (2), 270-6
    DOI 10.1016/0005-2787(72)90179-7, PubMed 4629425
  3. Lukanidin EM, Olsnes S, Pihl A (1972)
    Antigenic difference between informofers and protein bound to polyribosomal mRNA from rat liver
    Nat New Biol, 240 (98), 90-2
    DOI 10.1038/newbio240090a0, PubMed 4117892
  4. Olsnes S (1972)
    Toxic proteins inhibiting protein synthesis
    Naturwissenschaften, 59 (11), 497-502
    DOI 10.1007/BF00609814, PubMed 4657651
  5. Olsnes S, Heiberg R, Pihl A (1972)
    Deoxycholate-induced release of monosomes from rat liver polyribosomes
    Biochim Biophys Acta, 272 (1), 75-80
    DOI 10.1016/0005-2787(72)90035-4, PubMed 5043716
  6. Olsnes S, Pihl A (1972)
    Inhibition of peptide chain elongation
    Nature, 238 (5365), 459-61
    DOI 10.1038/238459a0, PubMed 4561855
  7. Olsnes S, Pihl A (1972)
    Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free system
    FEBS Lett, 28 (1), 48-50
    DOI 10.1016/0014-5793(72)80674-4, PubMed 4646874
  8. Olsnes S, Pihl A (1972)
    Possible function of the protein bound to nuclear complementary RNA
    FEBS Lett, 20 (2), 181-183
    DOI 10.1016/0014-5793(72)80788-9, PubMed 11946410
  9. Olsnes S, Pihl A (1972)
    Ricin - a potent inhibitor of protein synthesis
    FEBS Lett, 20 (3), 327-329
    DOI 10.1016/0014-5793(72)80098-x, PubMed 11946449
  10. Olsnes S, Spaeren U, Heiberg R, Pihl A (1972)
    Protein synthesis in the presence of non-ionic detergents in a cell-free system from rabbit reticulocytes
    Biochem J, 130 (1), 297-9
    DOI 10.1042/bj1300297, PubMed 4655435
  11. Spaeren U, Olsnes S, Pihl A (1972)
    Translation of mouse globin mRNA by isolated ribosomal subunits from rabbit reticulocytes
    Biochim Biophys Acta, 272 (4), 663-6
    DOI 10.1016/0005-2787(72)90525-4, PubMed 5050924

Publications 1971

  1. Heiberg R, Olsnes S, Pihl A (1971)
    On the mechanism of the inhibiting effect of aurin tricarboxylic acid on the binding of ribosomes to ribonucleic acids
    FEBS Lett, 18 (1), 169-171
    DOI 10.1016/0014-5793(71)80436-2, PubMed 11946112
  2. Olsnes S (1971)
    Further studies on the protein bound to the messenger RNA in mammalian polysomes
    Eur J Biochem, 23 (3), 557-63
    DOI 10.1111/j.1432-1033.1971.tb01654.x, PubMed 5003111
  3. Olsnes S (1971)
    Evidence that protein is bound to the rapidly labelled RNA in polyribosomes in vivo
    Eur J Biochem, 23 (2), 248-52
    DOI 10.1111/j.1432-1033.1971.tb01615.x, PubMed 5003205
  4. Olsnes S (1971)
    Characterization of the complex containing rapidly labelled RNA in EDTA-treated polyribosomes from rat liver
    Eur J Biochem, 18 (2), 242-51
    DOI 10.1111/j.1432-1033.1971.tb01237.x, PubMed 5541508
  5. Olsnes S (1971)
    The isolation of polysomes from rat liver. Contamination by membrane proteins with high affinity to ribosomes
    Biochim Biophys Acta, 232 (4), 705-16
    PubMed 5556851