Publications by Karl-Johan Malmberg

80 publications found

Publications 2019

1. Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ (2019)
   Remodeling of secretory lysosomes during education tunes functional potential in NK cells
   Nat Commun, 10 (1), 514
   DOI 10.1038/s41467-019-08384-x, PubMed 30705279

Publications 2018

1. Björklund AT, Carlsten M, Sohlberg E, Liu LL, Clancy T, Karimi M, Cooley S, Miller JS, Klimkowska M, Schaffer M, Watz E, Wikström K, Blomberg P, Wahlin BE, Palma M, Hansson L, Ljungman P, Hellström-Lindberg E, Ljunggren HG, Malmberg KJ (2018)
   Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML
   Clin Cancer Res, 24 (8), 1834-1844
   DOI 10.1158/1078-0432.CCR-17-3196, PubMed 29444931
2. De Santis F, Del Vecchio M, Castagnoli L, De Braud F, Di Cosimo S, Franceschini D, Fucà G, Hiscott J, Malmberg KJ, McGranahan N, Pietrantonio F, Rivoltini L, Sangaletti S, Tagliabue E, Tripodo C, Vernieri C, Zitvogel L, Pupa SM, Di Nicola M (2018)
   Innovative therapy, monoclonal antibodies, and beyond: Highlights from the eighth annual meeting
   Cytokine Growth Factor Rev, 44, 1-10
   DOI 10.1016/j.cytogfr.2018.10.005, PubMed 30393044
3. Jacobs B, Pfefferle A, Clement D, Berg-Larsen A, Saetersmoen ML, Lorenz S, Wiiger MT, Goodridge JP, Malmberg KJ (2018)
   Induction of the BIM Short Splice Variant Sensitizes Proliferating NK Cells to IL-15 Withdrawal
   J Immunol, 202 (3), 736-746
   DOI 10.4049/jimmunol.1801146, PubMed 30578306
4. Oei VYS, Siernicka M, Graczyk-Jarzynka A, Hoel HJ, Yang W, Palacios D, Almåsbak H, Bajor M, Clement D, Brandt L, Önfelt B, Goodridge J, Winiarska M, Zagozdzon R, Olweus J, Kyte JA, Malmberg KJ (2018)
   Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors
   Cancer Immunol Res, 6 (4), 467-480
   DOI 10.1158/2326-6066.CIR-17-0207, PubMed 29459477
5. Saetersmoen ML, Hammer Q, Valamehr B, Kaufman DS, Malmberg KJ (2018)
   Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells
   Semin Immunopathol, 41 (1), 59-68
   DOI 10.1007/s00281-018-0721-x, PubMed 30361801

Publications 2017

1. Clancy T, Dannenfelser R, Troyanskaya O, Malmberg KJ, Hovig E, Kristensen V (2017)
   Bioinformatics Approaches to Profile the Tumor Microenvironment for Immunotherapeutic Discovery
   Curr Pharm Des, 23 (32), 4716-4725
   DOI 10.2174/1381612823666170710154936, PubMed 28699527
2. Liu LL, Béziat V, Oei VYS, Pfefferle A, Schaffer M, Lehmann S, Hellström-Lindberg E, Söderhäll S, Heyman M, Grandér D, Malmberg KJ (2017)
   Ex Vivo Expanded Adaptive NK Cells Effectively Kill Primary Acute Lymphoblastic Leukemia Cells
   Cancer Immunol Res, 5 (8), 654-665
   DOI 10.1158/2326-6066.CIR-16-0296, PubMed 28637877
3. Malmberg KJ, Carlsten M, Björklund A, Sohlberg E, Bryceson YT, Ljunggren HG (2017)
   Natural killer cell-mediated immunosurveillance of human cancer
   Semin Immunol, 31, 20-29
   DOI 10.1016/j.smim.2017.08.002, PubMed 28888619
4. Malmberg KJ, Sohlberg E, Goodridge JP, Ljunggren HG (2017)
   Immune selection during tumor checkpoint inhibition therapy paves way for NK-cell "missing self" recognition
   Immunogenetics, 69 (8-9), 547-556
   DOI 10.1007/s00251-017-1011-9, PubMed 28699110
5. Wagner JA, Rosario M, Romee R, Berrien-Elliott MM, Schneider SE, Leong JW, Sullivan RP, Jewell BA, Becker-Hapak M, Schappe T, Abdel-Latif S, Ireland AR, Jaishankar D, King JA, Vij R, Clement D, Goodridge J, Malmberg KJ, Wong HC, Fehniger TA (2017)
   CD56bright NK cells exhibit potent antitumor responses following IL-15 priming
   J Clin Invest, 127 (11), 4042-4058
   DOI 10.1172/JCI90387, PubMed 28972539

Publications 2016

1. Björklund AT, Clancy T, Goodridge JP, Béziat V, Schaffer M, Hovig E, Ljunggren HG, Ljungman PT, Malmberg KJ (2016)
   Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
   J Immunol, 196 (3), 1400-11
   DOI 10.4049/jimmunol.1501434, PubMed 26746188
2. Horowitz A, Djaoud Z, Nemat-Gorgani N, Blokhuis J, Hilton HG, Béziat V, Malmberg KJ, Norman PJ, Guethlein LA, Parham P (2016)
   Class I HLA haplotypes form two schools that educate NK cells in different ways
   Sci Immunol, 1 (3)
   DOI 10.1126/sciimmunol.aag1672, PubMed 27868107
3. Landtwing V, Raykova A, Pezzino G, Béziat V, Marcenaro E, Graf C, Moretta A, Capaul R, Zbinden A, Ferlazzo G, Malmberg KJ, Chijioke O, Münz C (2016)
   Cognate HLA absence in trans diminishes human NK cell education
   J Clin Invest, 126 (10), 3772-3782
   DOI 10.1172/JCI86923, PubMed 27571408
4. Liu LL, Landskron J, Ask EH, Enqvist M, Sohlberg E, Traherne JA, Hammer Q, Goodridge JP, Larsson S, Jayaraman J, Oei VYS, Schaffer M, Taskén K, Ljunggren HG, Romagnani C, Trowsdale J, Malmberg KJ, Béziat V (2016)
   Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans
   Cell Rep, 15 (5), 1088-1099
   DOI 10.1016/j.celrep.2016.04.005, PubMed 27117418
5. Mensali N, Ying F, Sheng VO, Yang W, Walseng E, Kumari S, Fallang LE, Kolstad A, Uckert W, Malmberg KJ, Wälchli S, Olweus J (2016)
   Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA
   Oncoimmunology, 5 (5), e1138199
   DOI 10.1080/2162402X.2016.1138199, PubMed 27467957

Publications 2015

1. Béziat V, Sleiman M, Goodridge JP, Kaarbø M, Liu LL, Rollag H, Ljunggren HG, Zimmer J, Malmberg KJ (2015)
   Polyclonal Expansion of NKG2C(+) NK Cells in TAP-Deficient Patients
   Front Immunol, 6, 507
   DOI 10.3389/fimmu.2015.00507, PubMed 26500647
2. Enqvist M, Ask EH, Forslund E, Carlsten M, Abrahamsen G, Béziat V, Andersson S, Schaffer M, Spurkland A, Bryceson Y, Önfelt B, Malmberg KJ (2015)
   Coordinated expression of DNAM-1 and LFA-1 in educated NK cells
   J Immunol, 194 (9), 4518-27
   DOI 10.4049/jimmunol.1401972, PubMed 25825444
3. Forslund E, Sohlberg E, Enqvist M, Olofsson PE, Malmberg KJ, Önfelt B (2015)
   Microchip-Based Single-Cell Imaging Reveals That CD56dimCD57-KIR-NKG2A+ NK Cells Have More Dynamic Migration Associated with Increased Target Cell Conjugation and Probability of Killing Compared to CD56dimCD57-KIR-NKG2A- NK Cells
   J Immunol, 195 (7), 3374-81
   DOI 10.4049/jimmunol.1500171, PubMed 26320254
4. Goodridge JP, Önfelt B, Malmberg KJ (2015)
   Newtonian cell interactions shape natural killer cell education
   Immunol Rev, 267 (1), 197-213
   DOI 10.1111/imr.12325, PubMed 26284479
5. Liu LL, Pfefferle A, Yi Sheng VO, Björklund AT, Béziat V, Goodridge JP, Malmberg KJ (2015)
   Harnessing adaptive natural killer cells in cancer immunotherapy
   Mol Oncol, 9 (10), 1904-17
   DOI 10.1016/j.molonc.2015.10.001, PubMed 26604011
6. Schlums H, Cichocki F, Tesi B, Theorell J, Beziat V, Holmes TD, Han H, Chiang SC, Foley B, Mattsson K, Larsson S, Schaffer M, Malmberg KJ, Ljunggren HG, Miller JS, Bryceson YT (2015)
   Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function
   Immunity, 42 (3), 443-56
   DOI 10.1016/j.immuni.2015.02.008, PubMed 25786176
7. Sobecks RM, Wang T, Askar M, Gallagher MM, Haagenson M, Spellman S, Fernandez-Vina M, Malmberg KJ, Müller C, Battiwalla M, Gajewski J, Verneris MR, Ringdén O, Marino S, Davies S, Dehn J, Bornhäuser M, Inamoto Y, Woolfrey A, Shaw P, Pollack M, Weisdorf D, Milller J, Hurley C, Lee SJ et al. (2015)
   Impact of KIR and HLA Genotypes on Outcomes after Reduced-Intensity Conditioning Hematopoietic Cell Transplantation
   Biol Blood Marrow Transplant, 21 (9), 1589-96
   DOI 10.1016/j.bbmt.2015.05.002, PubMed 25960307
8. Sohlberg E, Pfefferle A, Andersson S, Baumann BC, Hellström-Lindberg E, Malmberg KJ (2015)
   Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome
   Oncotarget, 6 (33), 34178-90
   DOI 10.18632/oncotarget.6213, PubMed 26497557
9. von Bahr L, Blennow O, Alm J, Björklund A, Malmberg KJ, Mougiakakos D, Le Blanc A, Oefner PJ, Labopin M, Ljungman P, Le Blanc K (2015)
   Increased incidence of chronic GvHD and CMV disease in patients with vitamin D deficiency before allogeneic stem cell transplantation
   Bone Marrow Transplant, 50 (9), 1217-23
   DOI 10.1038/bmt.2015.123, PubMed 26030049

Publications 2014

1. Azzi T, Lünemann A, Murer A, Ueda S, Béziat V, Malmberg KJ, Staubli G, Gysin C, Berger C, Münz C, Chijioke O, Nadal D (2014)
   Role for early-differentiated natural killer cells in infectious mononucleosis
   Blood, 124 (16), 2533-43
   DOI 10.1182/blood-2014-01-553024, PubMed 25205117
2. Béziat V, Traherne J, Malmberg JA, Ivarsson MA, Björkström NK, Retière C, Ljunggren HG, Michaëlsson J, Trowsdale J, Malmberg KJ (2014)
   Tracing dynamic expansion of human NK-cell subsets by high-resolution analysis of KIR repertoires and cellular differentiation
   Eur J Immunol, 44 (7), 2192-6
   DOI 10.1002/eji.201444464, PubMed 24723455
3. Lunemann S, Malone DF, Grabowski J, Port K, Béziat V, Bremer B, Malmberg KJ, Manns MP, Sandberg JK, Cornberg M, Ljunggren HG, Wedemeyer H, Björkström NK (2014)
   Effects of HDV infection and pegylated interferon α treatment on the natural killer cell compartment in chronically infected individuals
   Gut, 64 (3), 469-82
   DOI 10.1136/gutjnl-2014-306767, PubMed 24721903
4. Munneke JM, Björklund AT, Mjösberg JM, Garming-Legert K, Bernink JH, Blom B, Huisman C, van Oers MH, Spits H, Malmberg KJ, Hazenberg MD (2014)
   Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease
   Blood, 124 (5), 812-21
   DOI 10.1182/blood-2013-11-536888, PubMed 24855210

Publications 2013

1. Bengnér M, Béziat V, Ernerudh J, Nilsson BO, Löfgren S, Wikby A, Malmberg KJ, Strindhall J (2013)
   Independent skewing of the T cell and NK cell compartments associated with cytomegalovirus infection suggests division of labor between innate and adaptive immunity
   Age (Dordr), 36 (2), 571-82
   DOI 10.1007/s11357-013-9587-y, PubMed 24065293
2. Béziat V, Liu LL, Malmberg JA, Ivarsson MA, Sohlberg E, Björklund AT, Retière C, Sverremark-Ekström E, Traherne J, Ljungman P, Schaffer M, Price DA, Trowsdale J, Michaëlsson J, Ljunggren HG, Malmberg KJ (2013)
   NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs
   Blood, 121 (14), 2678-88
   DOI 10.1182/blood-2012-10-459545, PubMed 23325834
3. Béziat V, Traherne JA, Liu LL, Jayaraman J, Enqvist M, Larsson S, Trowsdale J, Malmberg KJ (2013)
   Influence of KIR gene copy number on natural killer cell education
   Blood, 121 (23), 4703-7
   DOI 10.1182/blood-2012-10-461442, PubMed 23637128
4. Sternberg-Simon M, Brodin P, Pickman Y, Onfelt B, Kärre K, Malmberg KJ, Höglund P, Mehr R (2013)
   Natural killer cell inhibitory receptor expression in humans and mice: a closer look
   Front Immunol, 4, 65
   DOI 10.3389/fimmu.2013.00065, PubMed 23532016
5. Vanherberghen B, Olofsson PE, Forslund E, Sternberg-Simon M, Khorshidi MA, Pacouret S, Guldevall K, Enqvist M, Malmberg KJ, Mehr R, Önfelt B (2013)
   Classification of human natural killer cells based on migration behavior and cytotoxic response
   Blood, 121 (8), 1326-34
   DOI 10.1182/blood-2012-06-439851, PubMed 23287857

Publications 2012

1. Björkström NK, Béziat V, Cichocki F, Liu LL, Levine J, Larsson S, Koup RA, Anderson SK, Ljunggren HG, Malmberg KJ (2012)
   CD8 T cells express randomly selected KIRs with distinct specificities compared with NK cells
   Blood, 120 (17), 3455-65
   DOI 10.1182/blood-2012-03-416867, PubMed 22968455
2. Malmberg KJ (2012)
   Toward a prime-boost regime for NK cells?
   Blood, 120 (24), 4663-4
   DOI 10.1182/blood-2012-09-457184, PubMed 23223209
3. Malmberg KJ, Beziat V, Ljunggren HG (2012)
   Spotlight on NKG2C and the human NK-cell response to CMV infection
   Eur J Immunol, 42 (12), 3141-5
   DOI 10.1002/eji.201243050, PubMed 23255011

Publications 2011

1. Béziat V, Dalgard O, Asselah T, Halfon P, Bedossa P, Boudifa A, Hervier B, Theodorou I, Martinot M, Debré P, Björkström NK, Malmberg KJ, Marcellin P, Vieillard V (2011)
   CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients
   Eur J Immunol, 42 (2), 447-57
   DOI 10.1002/eji.201141826, PubMed 22105371
2. Björkström NK, Svensson A, Malmberg KJ, Eriksson K, Ljunggren HG (2011)
   Characterization of natural killer cell phenotype and function during recurrent human HSV-2 infection
   PLoS One, 6 (11), e27664
   DOI 10.1371/journal.pone.0027664, PubMed 22110712
3. Enqvist M, Nilsonne G, Hammarfjord O, Wallin RP, Björkström NK, Björnstedt M, Hjerpe A, Ljunggren HG, Dobra K, Malmberg KJ, Carlsten M (2011)
   Selenite induces posttranscriptional blockade of HLA-E expression and sensitizes tumor cells to CD94/NKG2A-positive NK cells
   J Immunol, 187 (7), 3546-54
   DOI 10.4049/jimmunol.1100610, PubMed 21890659
4. Kuylenstierna C, Björkström NK, Andersson SK, Sahlström P, Bosnjak L, Paquin-Proulx D, Malmberg KJ, Ljunggren HG, Moll M, Sandberg JK (2011)
   NKG2D performs two functions in invariant NKT cells: direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d
   Eur J Immunol, 41 (7), 1913-23
   DOI 10.1002/eji.200940278, PubMed 21590763
5. Malmberg KJ, Michaëlsson J, Parham P, Ljunggren HG (2011)
   Killer cell immunoglobulin-like receptor workshop: insights into evolution, genetics, function, and translation
   Immunity, 35 (5), 653-7
   DOI 10.1016/j.immuni.2011.11.007, PubMed 22118518
6. Remberger M, Ackefors M, Berglund S, Blennow O, Dahllöf G, Dlugosz A, Garming-Legert K, Gertow J, Gustafsson B, Hassan M, Hassan Z, Hauzenberger D, Hägglund H, Karlsson H, Klingspor L, Kumlien G, Le Blanc K, Ljungman P, Machaczka M, Malmberg KJ, Marschall HU, Mattsson J, Olsson R, Omazic B, Sairafi D et al. (2011)
   Improved survival after allogeneic hematopoietic stem cell transplantation in recent years. A single-center study
   Biol Blood Marrow Transplant, 17 (11), 1688-97
   DOI 10.1016/j.bbmt.2011.05.001, PubMed 21620989

Publications 2010

1. Andersson S, Malmberg JA, Malmberg KJ (2010)
   Tolerant and diverse natural killer cell repertoires in the absence of selection
   Exp Cell Res, 316 (8), 1309-15
   DOI 10.1016/j.yexcr.2010.02.030, PubMed 20206161
2. Björklund AT, Schaffer M, Fauriat C, Ringdén O, Remberger M, Hammarstedt C, Barrett AJ, Ljungman P, Ljunggren HG, Malmberg KJ (2010)
   NK cells expressing inhibitory KIR for non-self-ligands remain tolerant in HLA-matched sibling stem cell transplantation
   Blood, 115 (13), 2686-94
   DOI 10.1182/blood-2009-07-229740, PubMed 20097883
3. Björkström NK, Fauriat C, Bryceson YT, Sandberg JK, Ljunggren HG, Malmberg KJ (2010)
   Analysis of the KIR repertoire in human NK cells by flow cytometry
   Methods Mol Biol, 612, 353-64
   DOI 10.1007/978-1-60761-362-6_24, PubMed 20033653
4. Björkström NK, Lindgren T, Stoltz M, Fauriat C, Braun M, Evander M, Michaëlsson J, Malmberg KJ, Klingström J, Ahlm C, Ljunggren HG (2010)
   Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus
   J Exp Med, 208 (1), 13-21
   DOI 10.1084/jem.20100762, PubMed 21173105
5. Björkström NK, Riese P, Heuts F, Andersson S, Fauriat C, Ivarsson MA, Björklund AT, Flodström-Tullberg M, Michaëlsson J, Rottenberg ME, Guzmán CA, Ljunggren HG, Malmberg KJ (2010)
   Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education
   Blood, 116 (19), 3853-64
   DOI 10.1182/blood-2010-04-281675, PubMed 20696944
6. Carlsten M, Baumann BC, Simonsson M, Jädersten M, Forsblom AM, Hammarstedt C, Bryceson YT, Ljunggren HG, Hellström-Lindberg E, Malmberg KJ (2010)
   Reduced DNAM-1 expression on bone marrow NK cells associated with impaired killing of CD34+ blasts in myelodysplastic syndrome
   Leukemia, 24 (9), 1607-16
   DOI 10.1038/leu.2010.149, PubMed 20613786
7. Fasth AE, Björkström NK, Anthoni M, Malmberg KJ, Malmström V (2010)
   Activating NK-cell receptors co-stimulate CD4(+)CD28(-) T cells in patients with rheumatoid arthritis
   Eur J Immunol, 40 (2), 378-87
   DOI 10.1002/eji.200939399, PubMed 19904767
8. Rotzius P, Thams S, Soehnlein O, Kenne E, Tseng CN, Björkström NK, Malmberg KJ, Lindbom L, Eriksson EE (2010)
   Distinct infiltration of neutrophils in lesion shoulders in ApoE-/- mice
   Am J Pathol, 177 (1), 493-500
   DOI 10.2353/ajpath.2010.090480, PubMed 20472897
9. Schellekens J, Schaffer M, Malmberg KJ, Madrigal JA, Marsh SG (2010)
   Identification of a novel KIR3DL1*072 allele by sequence-based typing
   Tissue Antigens, 76 (1), 74-5
   DOI 10.1111/j.1399-0039.2010.01464.x, PubMed 20210921
10. Taner SB, Pando MJ, Roberts A, Schellekens J, Marsh SG, Malmberg KJ, Parham P, Brodsky FM (2010)
    Interactions of NK cell receptor KIR3DL1*004 with chaperones and conformation-specific antibody reveal a functional folded state as well as predominant intracellular retention
    J Immunol, 186 (1), 62-72
    DOI 10.4049/jimmunol.0903657, PubMed 21115737

Publications 2009

1. Andersson S, Fauriat C, Malmberg JA, Ljunggren HG, Malmberg KJ (2009)
   KIR acquisition probabilities are independent of self-HLA class I ligands and increase with cellular KIR expression
   Blood, 114 (1), 95-104
   DOI 10.1182/blood-2008-10-184549, PubMed 19304956
2. Carlsten M, Malmberg KJ, Ljunggren HG (2009)
   Natural killer cell-mediated lysis of freshly isolated human tumor cells
   Int J Cancer, 124 (4), 757-62
   DOI 10.1002/ijc.24082, PubMed 19035446
3. Carlsten M, Norell H, Bryceson YT, Poschke I, Schedvins K, Ljunggren HG, Kiessling R, Malmberg KJ (2009)
   Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells
   J Immunol, 183 (8), 4921-30
   DOI 10.4049/jimmunol.0901226, PubMed 19801517
4. Curbo S, Gaudin R, Carlsten M, Malmberg KJ, Troye-Blomberg M, Ahlborg N, Karlsson A, Johansson M, Lundberg M (2009)
   Regulation of interleukin-4 signaling by extracellular reduction of intramolecular disulfides
   Biochem Biophys Res Commun, 390 (4), 1272-7
   DOI 10.1016/j.bbrc.2009.10.134, PubMed 19878651
5. Fasth AE, Dastmalchi M, Rahbar A, Salomonsson S, Pandya JM, Lindroos E, Nennesmo I, Malmberg KJ, Söderberg-Nauclér C, Trollmo C, Lundberg IE, Malmström V (2009)
   T cell infiltrates in the muscles of patients with dermatomyositis and polymyositis are dominated by CD28null T cells
   J Immunol, 183 (7), 4792-9
   DOI 10.4049/jimmunol.0803688, PubMed 19752224
6. Fauriat C, Ivarsson MA, Ljunggren HG, Malmberg KJ, Michaëlsson J (2009)
   Education of human natural killer cells by activating killer cell immunoglobulin-like receptors
   Blood, 115 (6), 1166-74
   DOI 10.1182/blood-2009-09-245746, PubMed 19903900
7. Malmberg KJ, Ljunggren HG (2009)
   Spotlight on IL-22-producing NK cell receptor-expressing mucosal lymphocytes
   Nat Immunol, 10 (1), 11-2
   DOI 10.1038/ni0109-11, PubMed 19088733

Publications 2008

1. Björkström NK, Gonzalez VD, Malmberg KJ, Falconer K, Alaeus A, Nowak G, Jorns C, Ericzon BG, Weiland O, Sandberg JK, Ljunggren HG (2008)
   Elevated numbers of Fc gamma RIIIA+ (CD16+) effector CD8 T cells with NK cell-like function in chronic hepatitis C virus infection
   J Immunol, 181 (6), 4219-28
   PubMed 18768879
2. Fauriat C, Andersson S, Björklund AT, Carlsten M, Schaffer M, Björkström NK, Baumann BC, Michaëlsson J, Ljunggren HG, Malmberg KJ (2008)
   Estimation of the size of the alloreactive NK cell repertoire: studies in individuals homozygous for the group A KIR haplotype
   J Immunol, 181 (9), 6010-9
   PubMed 18941190
3. Malmberg KJ, Bryceson YT, Carlsten M, Andersson S, Björklund A, Björkström NK, Baumann BC, Fauriat C, Alici E, Dilber MS, Ljunggren HG (2008)
   NK cell-mediated targeting of human cancer and possibilities for new means of immunotherapy
   Cancer Immunol Immunother, 57 (10), 1541-52
   DOI 10.1007/s00262-008-0492-7, PubMed 18317755

Publications 2007

1. Carlsten M, Björkström NK, Norell H, Bryceson Y, van Hall T, Baumann BC, Hanson M, Schedvins K, Kiessling R, Ljunggren HG, Malmberg KJ (2007)
   DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells
   Cancer Res, 67 (3), 1317-25
   DOI 10.1158/0008-5472.CAN-06-2264, PubMed 17283169
2. Gonzalez VD, Björkström NK, Malmberg KJ, Moll M, Kuylenstierna C, Michaëlsson J, Ljunggren HG, Sandberg JK (2007)
   Application of nine-color flow cytometry for detailed studies of the phenotypic complexity and functional heterogeneity of human lymphocyte subsets
   J Immunol Methods, 330 (1-2), 64-74
   DOI 10.1016/j.jim.2007.10.020, PubMed 18083186
3. Harlin H, Hanson M, Johansson CC, Sakurai D, Poschke I, Norell H, Malmberg KJ, Kiessling R (2007)
   The CD16- CD56(bright) NK cell subset is resistant to reactive oxygen species produced by activated granulocytes and has higher antioxidative capacity than the CD16+ CD56(dim) subset
   J Immunol, 179 (7), 4513-9
   PubMed 17878347
4. Hühn MH, Hultcrantz M, Lind K, Ljunggren HG, Malmberg KJ, Flodström-Tullberg M (2007)
   IFN-gamma production dominates the early human natural killer cell response to Coxsackievirus infection
   Cell Microbiol, 10 (2), 426-36
   DOI 10.1111/j.1462-5822.2007.01056.x, PubMed 17961184
5. Ljunggren HG, Malmberg KJ (2007)
   Prospects for the use of NK cells in immunotherapy of human cancer
   Nat Rev Immunol, 7 (5), 329-39
   DOI 10.1038/nri2073, PubMed 17438573

Publications 2006

1. Hanson MG, Ozenci V, Carlsten MC, Glimelius BL, Frödin JE, Masucci G, Malmberg KJ, Kiessling RV (2006)
   A short-term dietary supplementation with high doses of vitamin E increases NK cell cytolytic activity in advanced colorectal cancer patients
   Cancer Immunol Immunother, 56 (7), 973-84
   DOI 10.1007/s00262-006-0261-4, PubMed 17143612
2. Norell H, Carlsten M, Ohlum T, Malmberg KJ, Masucci G, Schedvins K, Altermann W, Handke D, Atkins D, Seliger B, Kiessling R (2006)
   Frequent loss of HLA-A2 expression in metastasizing ovarian carcinomas associated with genomic haplotype loss and HLA-A2-restricted HER-2/neu-specific immunity
   Cancer Res, 66 (12), 6387-94
   DOI 10.1158/0008-5472.CAN-06-0029, PubMed 16778217

Publications 2005

1. Malmberg KJ, Ljunggren HG (2005)
   Escape from immune- and nonimmune-mediated tumor surveillance
   Semin Cancer Biol, 16 (1), 16-31
   DOI 10.1016/j.semcancer.2005.07.007, PubMed 16140546
2. Malmberg KJ, Schaffer M, Ringdén O, Remberger M, Ljunggren HG (2005)
   KIR-ligand mismatch in allogeneic hematopoietic stem cell transplantation
   Mol Immunol, 42 (4), 531-4
   DOI 10.1016/j.molimm.2004.07.037, PubMed 15607809
3. Takahashi A, Hanson MG, Norell HR, Havelka AM, Kono K, Malmberg KJ, Kiessling RV (2005)
   Preferential cell death of CD8+ effector memory (CCR7-CD45RA-) T cells by hydrogen peroxide-induced oxidative stress
   J Immunol, 174 (10), 6080-7
   PubMed 15879102

Publications 2004

1. Malmberg KJ (2004)
   Effective immunotherapy against cancer: a question of overcoming immune suppression and immune escape?
   Cancer Immunol Immunother, 53 (10), 879-92
   DOI 10.1007/s00262-004-0577-x, PubMed 15338206
2. Schaffer M, Malmberg KJ, Ringdén O, Ljunggren HG, Remberger M (2004)
   Increased infection-related mortality in KIR-ligand-mismatched unrelated allogeneic hematopoietic stem-cell transplantation
   Transplantation, 78 (7), 1081-5
   PubMed 15480179

Publications 2002

1. Malmberg KJ, Lenkei R, Petersson M, Ohlum T, Ichihara F, Glimelius B, Frödin JE, Masucci G, Kiessling R (2002)
   A short-term dietary supplementation of high doses of vitamin E increases T helper 1 cytokine production in patients with advanced colorectal cancer
   Clin Cancer Res, 8 (6), 1772-8
   PubMed 12060616
2. Malmberg KJ, Levitsky V, Norell H, de Matos CT, Carlsten M, Schedvins K, Rabbani H, Moretta A, Söderström K, Levitskaya J, Kiessling R (2002)
   IFN-gamma protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism
   J Clin Invest, 110 (10), 1515-23
   DOI 10.1172/JCI15564, PubMed 12438449

Publications 2001

1. Charo J, Geluk A, Sundbäck M, Mirzai B, Diehl AD, Malmberg KJ, Achour A, Huriguchi S, van Meijgaarden KE, Drijfhout JW, Beekman N, van Veelen P, Ossendorp F, Ottenhoff TH, Kiessling R (2001)
   The identification of a common pathogen-specific HLA class I A*0201-restricted cytotoxic T cell epitope encoded within the heat shock protein 65
   Eur J Immunol, 31 (12), 3602-11
   DOI 10.1002/1521-4141(200112)31:12<3602::AID-IMMU3602gt;3.0.CO;2-L, PubMed 11745380
2. Malmberg KJ, Arulampalam V, Ichihara F, Petersson M, Seki K, Andersson T, Lenkei R, Masucci G, Pettersson S, Kiessling R (2001)
   Inhibition of activated/memory (CD45RO(+)) T cells by oxidative stress associated with block of NF-kappaB activation
   J Immunol, 167 (5), 2595-601
   PubMed 11509600

Publications 1999

1. Rongcun Y, Salazar-Onfray F, Charo J, Malmberg KJ, Evrin K, Maes H, Kono K, Hising C, Petersson M, Larsson O, Lan L, Appella E, Sette A, Celis E, Kiessling R (1999)
   Identification of new HER2/neu-derived peptide epitopes that can elicit specific CTL against autologous and allogeneic carcinomas and melanomas
   J Immunol, 163 (2), 1037-44
   PubMed 10395702