Publications from OUS - Lymphoma biology group (Myklebust)
281 publications found
Publications 2024
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Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma
Blood Cancer J, 14 (1), 147
DOI 10.1038/s41408-024-01124-5, PubMed 39191762 -
Cell surface marker heterogeneity in human myeloma cell lines for modeling of disease and therapy
Sci Rep, 14 (1), 28805
DOI 10.1038/s41598-024-80263-y, PubMed 39567630 -
Peripheral immune cells in metastatic breast cancer patients display a systemic immunosuppressed signature consistent with chronic inflammation
NPJ Breast Cancer, 10 (1), 30
DOI 10.1038/s41523-024-00638-2, PubMed 38653982 -
Disruption of KLHL6 Fuels Oncogenic Antigen Receptor Signaling in B-Cell Lymphoma
Blood Cancer Discov, 5 (5), 331-352
DOI 10.1158/2643-3230.BCD-23-0182, PubMed 38630892 -
The Tumor Immune Microenvironment in Breast Cancer Progression
Acta Oncol, 63, 359-367
DOI 10.2340/1651-226X.2024.33008, PubMed 38779867
Publications 2023
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Efficient chimeric antigen receptor targeting of a central epitope of CD22
J Biol Chem, 299 (7), 104883
DOI 10.1016/j.jbc.2023.104883, PubMed 37269947 -
The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy
Haematologica, 108 (9), 2454-2466
DOI 10.3324/haematol.2022.282289, PubMed 36861406 -
Diversity of intratumoral regulatory T cells in B-cell non-Hodgkin lymphoma
Blood Adv, 7 (23), 7216-7230
DOI 10.1182/bloodadvances.2023010158, PubMed 37695745 -
High-resolution alignment of single-cell and spatial transcriptomes with CytoSPACE
Nat Biotechnol, 41 (11), 1543-1548
DOI 10.1038/s41587-023-01697-9, PubMed 36879008
Publications 2022
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Mechanism of CD79A and CD79B Support for IgM+ B Cell Fitness through B Cell Receptor Surface Expression
J Immunol, 209 (10), 2042-2053
DOI 10.4049/jimmunol.2200144, PubMed 36426942
Publications 2021
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A simplified frailty score predicts survival and can aid treatment-intensity decisions in older patients with DLBCL
Blood Adv, 5 (22), 4771-4782
DOI 10.1182/bloodadvances.2021004777, PubMed 34543384 -
An extended APOBEC3A mutation signature in cancer
Nat Commun, 12 (1), 1602
DOI 10.1038/s41467-021-21891-0, PubMed 33707442 -
Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
Sci Rep, 11 (1), 6317
DOI 10.1038/s41598-021-85613-8, PubMed 33737576 -
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
Mol Oncol, 16 (1), 88-103
DOI 10.1002/1878-0261.13047, PubMed 34165864 -
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia
Cancer Res, 81 (22), 5733-5744
DOI 10.1158/0008-5472.CAN-21-0061, PubMed 34593524 -
What It Takes to Transform a T Cell
Cancer Res, 81 (12), 3160-3161
DOI 10.1158/0008-5472.CAN-21-0784, PubMed 34224376 -
The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma
Cancer Cell, 39 (10), 1422-1437.e10
DOI 10.1016/j.ccell.2021.08.011, PubMed 34597589
Publications 2020
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Gene Editing in B-Lymphoma Cell Lines Using CRISPR/Cas9 Technology
Methods Mol Biol, 2115, 445-454
DOI 10.1007/978-1-0716-0290-4_25, PubMed 32006416 -
The DLBCL90 gene-expression assay identifies double-hit lymphomas with high sensitivity in patients from two phase II clinical trials with high-risk diffuse large B-cell lymphoma
EJHaem, 2 (1), 104-108
DOI 10.1002/jha2.109, PubMed 35846101 -
Minimal relapse risk and early normalization of survival for patients with Burkitt lymphoma treated with intensive immunochemotherapy: an international study of 264 real-world patients
Br J Haematol, 189 (4), 661-671
DOI 10.1111/bjh.16425, PubMed 32017050 -
Combinatorial CAR design improves target restriction
J Biol Chem, 296, 100116
DOI 10.1074/jbc.RA120.016234, PubMed 33234592 -
Tuning the Antigen Density Requirement for CAR T-cell Activity
Cancer Discov, 10 (5), 702-723
DOI 10.1158/2159-8290.CD-19-0945, PubMed 32193224 -
Cell Cycle Analysis and Relevance for Single-Cell Gating in Mass Cytometry
Cytometry A, 97 (8), 832-844
DOI 10.1002/cyto.a.23960, PubMed 31943748 -
Reduced polyfunctional T cells and increased cellular activation markers in adult allergy patients reporting adverse reactions to food
BMC Immunol, 21 (1), 43
DOI 10.1186/s12865-020-00373-w, PubMed 32698761 -
Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
Blood Adv, 4 (9), 1859-1866
DOI 10.1182/bloodadvances.2019001325, PubMed 32374878
Publications 2019
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Expanding the Clinical Cytometry Toolbox-Receptor Occupancy by Mass Cytometry
Cytometry A, 95 (10), 1046-1048
DOI 10.1002/cyto.a.23784, PubMed 31046178 -
Human Germinal Center B Cells Differ from Naïve and Memory B Cells in CD40 Expression and CD40L-Induced Signaling Response
Cytometry A, 95 (4), 442-449
DOI 10.1002/cyto.a.23737, PubMed 30838773 -
TIGIT and PD-1 Mark Intratumoral T Cells with Reduced Effector Function in B-cell Non-Hodgkin Lymphoma
Cancer Immunol Res, 7 (3), 355-362
DOI 10.1158/2326-6066.CIR-18-0351, PubMed 30659053 -
Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma
Blood Adv, 3 (8), 1230-1243
DOI 10.1182/bloodadvances.2018029678, PubMed 30979721 -
NK cells specifically TCR-dressed to kill cancer cells
EBioMedicine, 40, 106-117
DOI 10.1016/j.ebiom.2019.01.031, PubMed 30665853 -
A clinico-molecular predictor identifies follicular lymphoma patients at risk of early transformation after first-line immunotherapy
Haematologica, 104 (10), e460-e464
DOI 10.3324/haematol.2018.209080, PubMed 30846496 -
Huge whole-genome study of human metastatic cancers
Nature, 575 (7781), 60-61
DOI 10.1038/d41586-019-03123-0, PubMed 31690848
Publications 2018
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The MCL35 gene expression proliferation assay predicts high-risk MCL patients in a Norwegian cohort of younger patients given intensive first line therapy
Br J Haematol, 183 (2), 225-234
DOI 10.1111/bjh.15518, PubMed 30080252 -
Molecular classification of primary mediastinal large B-cell lymphoma using routinely available tissue specimens
Blood, 132 (22), 2401-2405
DOI 10.1182/blood-2018-05-851154, PubMed 30257882 -
Sample-Index Misassignment Impacts Tumour Exome Sequencing
Sci Rep, 8 (1), 5307
DOI 10.1038/s41598-018-23563-4, PubMed 29593270 -
Artesunate shows potent anti-tumor activity in B-cell lymphoma
J Hematol Oncol, 11 (1), 23
DOI 10.1186/s13045-018-0561-0, PubMed 29458389
Publications 2017
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BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5
PLoS One, 12 (5), e0177188
DOI 10.1371/journal.pone.0177188, PubMed 28489883 -
Human c-SRC kinase (CSK) overexpression makes T cells dummy
Cancer Immunol Immunother, 67 (4), 525-536
DOI 10.1007/s00262-017-2105-9, PubMed 29248956 -
T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth
Oncoimmunology, 6 (4), e1302631
DOI 10.1080/2162402X.2017.1302631, PubMed 28507809 -
T Cells Expressing Checkpoint Receptor TIGIT Are Enriched in Follicular Lymphoma Tumors and Characterized by Reversible Suppression of T-cell Receptor Signaling
Clin Cancer Res, 24 (4), 870-881
DOI 10.1158/1078-0432.CCR-17-2337, PubMed 29217528 -
Fishing therapeutic T-cell receptors in healthy donor blood, is safety predictable?
Transl. Cancer Res., 6 3, S622-S624
DOI 10.21037/tcr.2017.05.25 -
New Molecular Assay for the Proliferation Signature in Mantle Cell Lymphoma Applicable to Formalin-Fixed Paraffin-Embedded Biopsies
J Clin Oncol, 35 (15), 1668-1677
DOI 10.1200/JCO.2016.70.7901, PubMed 28291392 -
Defective IL-4 signaling in T cells defines severe common variable immunodeficiency
J Autoimmun, 81, 110-119
DOI 10.1016/j.jaut.2017.04.004, PubMed 28476239 -
A TCR-based Chimeric Antigen Receptor
Sci Rep, 7 (1), 10713
DOI 10.1038/s41598-017-11126-y, PubMed 28878363 -
Mass Cytometry of Follicular Lymphoma Tumors Reveals Intrinsic Heterogeneity in Proteins Including HLA-DR and a Deficit in Nonmalignant Plasmablast and Germinal Center B-Cell Populations
Cytometry B Clin Cytom, 92 (1), 79-87
DOI 10.1002/cyto.b.21498, PubMed 27933753
Publications 2016
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Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants
Mol Ther, 24 (9), 1675-85
DOI 10.1038/mt.2016.134, PubMed 27377043 -
The tumour microenvironment influences survival and time to transformation in follicular lymphoma in the rituximab era
Br J Haematol, 175 (1), 102-14
DOI 10.1111/bjh.14201, PubMed 27341313 -
Myeloid cell leukaemia 1 has a vital role in retinoic acid-mediated protection of Toll-like receptor 9-stimulated B cells from spontaneous and DNA damage-induced apoptosis
Immunology, 149 (1), 62-73
DOI 10.1111/imm.12629, PubMed 27278254 -
T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy
Oncoimmunology, 5 (12), e1249090
DOI 10.1080/2162402X.2016.1249090, PubMed 28123886 -
Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA
Oncoimmunology, 5 (5), e1138199
DOI 10.1080/2162402X.2016.1138199, PubMed 27467957 -
Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling
Blood, 129 (6), 759-770
DOI 10.1182/blood-2016-05-718494, PubMed 28011673 -
Patterns of constitutively phosphorylated kinases in B cells are associated with disease severity in common variable immunodeficiency
Clin Immunol, 175, 69-74
DOI 10.1016/j.clim.2016.11.014, PubMed 27919819
Publications 2015
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Computerized image analysis of the Ki-67 proliferation index in mantle cell lymphoma
Histopathology, 67 (1), 62-9
DOI 10.1111/his.12624, PubMed 25431344 -
Content of endothelial progenitor cells in autologous stem cell grafts predict survival after transplantation for multiple myeloma
Biol Blood Marrow Transplant, 21 (5), 840-7
DOI 10.1016/j.bbmt.2014.12.027, PubMed 25689789 -
New distinct compartments in the G2 phase of the cell cycle defined by the levels of γH2AX
Cell Cycle, 14 (20), 3261-9
DOI 10.1080/15384101.2015.1087617, PubMed 26317799 -
Incidence of Data Duplications in a Randomly Selected Pool of Life Science Publications
Sci Eng Ethics, 22 (2), 487-96
DOI 10.1007/s11948-015-9668-7, PubMed 26065681 -
The targeting of human and mouse B lymphocytes by dasatinib
Exp Hematol, 43 (5), 352-363.e4
DOI 10.1016/j.exphem.2015.01.008, PubMed 25641047 -
Magnetic bead-based isolation of exosomes
Methods Mol Biol, 1218, 465-81
DOI 10.1007/978-1-4939-1538-5_27, PubMed 25319668 -
Cutting Edge: Redox Signaling Hypersensitivity Distinguishes Human Germinal Center B Cells
J Immunol, 195 (4), 1364-1367
DOI 10.4049/jimmunol.1500904, PubMed 26157177 -
Unpredicted phenotypes of two mutants of the TcR DMF5
J Immunol Methods, 425, 37-44
DOI 10.1016/j.jim.2015.06.006, PubMed 26079729 -
Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
ACS Chem Biol, 11 (1), 251-62
DOI 10.1021/acschembio.5b00734, PubMed 26569462 -
Soluble T-cell receptors produced in human cells for targeted delivery
PLoS One, 10 (4), e0119559
DOI 10.1371/journal.pone.0119559, PubMed 25875651
Publications 2014
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A gene panel, including LRP12, is frequently hypermethylated in major types of B-cell lymphoma
PLoS One, 9 (9), e104249
DOI 10.1371/journal.pone.0104249, PubMed 25226156 -
High dose chemotherapy with autologous stem cell transplant for patients with transformed B-cell non-Hodgkin lymphoma in the rituximab era
Leuk Lymphoma, 55 (10), 2319-27
DOI 10.3109/10428194.2013.871632, PubMed 24432894 -
Combining MYC, BCL2 and TP53 gene and protein expression alterations improves risk stratification in diffuse large B-cell lymphoma
Leuk Lymphoma, 56 (6), 1742-9
DOI 10.3109/10428194.2014.970550, PubMed 25284491 -
Expression of B-cell surface antigens in subpopulations of exosomes released from B-cell lymphoma cells
Clin Ther, 36 (6), 847-862.e1
DOI 10.1016/j.clinthera.2014.05.010, PubMed 24952935 -
Prognostic influence of macrophages in patients with diffuse large B-cell lymphoma: a correlative study from a Nordic phase II trial
Haematologica, 100 (2), 238-45
DOI 10.3324/haematol.2014.113472, PubMed 25381134 -
Determining cell-of-origin subtypes of diffuse large B-cell lymphoma using gene expression in formalin-fixed paraffin-embedded tissue
Blood, 123 (8), 1214-7
DOI 10.1182/blood-2013-11-536433, PubMed 24398326 -
Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms
Cancer Discov, 4 (4), 480-93
DOI 10.1158/2159-8290.CD-13-0915, PubMed 24491438
Publications 2013
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Signaling pathways in lymphoma: pathogenesis and therapeutic targets
Future Oncol, 9 (10), 1549-71
DOI 10.2217/fon.13.113, PubMed 24106904 -
Identification of highly methylated genes across various types of B-cell non-hodgkin lymphoma
PLoS One, 8 (11), e79602
DOI 10.1371/journal.pone.0079602, PubMed 24260260 -
Colorectal cancer DNA methylation marker panel validated with high performance in Non-Hodgkin lymphoma
Epigenetics, 9 (3), 428-36
DOI 10.4161/epi.27554, PubMed 24362313 -
Whole-genome integrative analysis reveals expression signatures predicting transformation in follicular lymphoma
Blood, 123 (7), 1051-4
DOI 10.1182/blood-2013-07-512392, PubMed 24357726 -
EZH2 mutations are frequent and represent an early event in follicular lymphoma
Blood, 122 (18), 3165-8
DOI 10.1182/blood-2013-04-496893, PubMed 24052547 -
Karyotyping of diffuse large B-cell lymphomas: loss of 17p is associated with poor patient outcome
Eur J Haematol, 91 (4), 332-8
DOI 10.1111/ejh.12171, PubMed 23859481 -
Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes
Proc Natl Acad Sci U S A, 111 (1), 403-8
DOI 10.1073/pnas.1306549111, PubMed 24344295 -
Higher World Health Organization grades of follicular lymphoma correlate with better outcome in two Nordic Lymphoma Group trials of rituximab without chemotherapy
Leuk Lymphoma, 55 (2), 288-95
DOI 10.3109/10428194.2013.802778, PubMed 23662992 -
Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation
Eur J Immunol, 44 (3), 774-84
DOI 10.1002/eji.201343671, PubMed 24293164 -
Influence of polymorphisms in genes encoding immunoregulatory proteins and metabolizing enzymes on susceptibility and outcome in patients with diffuse large B-cell lymphoma treated with rituximab
Leuk Lymphoma, 54 (10), 2205-14
DOI 10.3109/10428194.2013.774392, PubMed 23391141
Publications 2012
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SARA is dispensable for functional TGF-β signaling
FEBS Lett, 586 (19), 3367-72
DOI 10.1016/j.febslet.2012.07.027, PubMed 22819827 -
Phospho-specific flow cytometry identifies aberrant signaling in indolent B-cell lymphoma
BMC Cancer, 12, 478
DOI 10.1186/1471-2407-12-478, PubMed 23072591 -
Altered BCR and CD40 signalling are associated with clinical outcome in small lymphocytic lymphoma/chronic lymphocytic leukaemia and marginal zone lymphoma patients
Br J Haematol, 159 (5), 604-8
DOI 10.1111/bjh.12073, PubMed 23043253 -
Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma
PLoS One, 7 (10), e46117
DOI 10.1371/journal.pone.0046117, PubMed 23049692 -
Effect of cycloheximide on epidermal growth factor receptor trafficking and signaling
FEBS Lett, 586 (20), 3575-81
DOI 10.1016/j.febslet.2012.08.022, PubMed 22971756 -
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
Nature, 490 (7418), 116-20
DOI 10.1038/nature11378, PubMed 22885699 -
Polymorphisms in genes encoding interleukin-10 and drug metabolizing enzymes GSTP1, GSTT1, GSTA1 and UGT1A1 influence risk and outcome in Hodgkin lymphoma
Leuk Lymphoma, 53 (10), 1934-44
DOI 10.3109/10428194.2012.682307, PubMed 22475179 -
Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnα1 and Kpnβ1
Traffic, 13 (5), 650-64
DOI 10.1111/j.1600-0854.2012.01341.x, PubMed 22321063
Publications 2011
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Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment
Blood, 118 (5), 1350-8
DOI 10.1182/blood-2011-03-345272, PubMed 21670469 -
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC
Leukemia, 26 (5), 1073-80
DOI 10.1038/leu.2011.263, PubMed 21941367 -
Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7
Eur J Immunol, 41 (11), 3135-45
DOI 10.1002/eji.201141558, PubMed 21898381 -
Side population cells in highly enriched CD34-positive cells from peripheral blood progenitor cells identify an immature subtype of hematopoietic progenitor cells but do not predict time to engraftment in patients treated with high-dose therapy
Eur J Haematol, 87 (6), 494-502
DOI 10.1111/j.1600-0609.2011.01681.x, PubMed 21752097 -
LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome
Haematologica, 96 (7), 980-6
DOI 10.3324/haematol.2011.040568, PubMed 21459790 -
The amount of DNA damage needed to activate the radiation-induced G2 checkpoint varies between single cells
Radiother Oncol, 101 (1), 24-7
DOI 10.1016/j.radonc.2011.05.060, PubMed 21722983 -
Clinical significance of the WHO grades of follicular lymphoma in a population-based cohort of 505 patients with long follow-up times
Br J Haematol, 156 (2), 225-33
DOI 10.1111/j.1365-2141.2011.08942.x, PubMed 22126847
Publications 2010
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TGF-β-induced growth inhibition in B-cell lymphoma correlates with Smad1/5 signalling and constitutively active p38 MAPK
BMC Immunol, 11, 57
DOI 10.1186/1471-2172-11-57, PubMed 21092277 -
Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma
Cell, 142 (5), 699-713
DOI 10.1016/j.cell.2010.07.044, PubMed 20813259 -
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
Nature, 463 (7277), 88-92
DOI 10.1038/nature08638, PubMed 20054396 -
Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones
Blood, 116 (9), 1489-97
DOI 10.1182/blood-2010-03-272278, PubMed 20505157 -
Both copy number and sequence variations affect expression of human DEFB4
Genes Immun, 11 (6), 458-66
DOI 10.1038/gene.2010.19, PubMed 20445567 -
B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression
Proc Natl Acad Sci U S A, 107 (29), 12747-54
DOI 10.1073/pnas.1002057107, PubMed 20543139 -
Oncogenically active MYD88 mutations in human lymphoma
Nature, 470 (7332), 115-9
DOI 10.1038/nature09671, PubMed 21179087 -
Cooperative epigenetic modulation by cancer amplicon genes
Cancer Cell, 18 (6), 590-605
DOI 10.1016/j.ccr.2010.11.013, PubMed 21156283 -
[Close cooperation, but not oversteering]
Tidsskr Nor Laegeforen, 130 (6), 590-1
DOI 10.4045/tidsskr.10.0153, PubMed 20348990 -
[Leadership and academic competence]
Tidsskr Nor Laegeforen, 130 (6), 591
DOI 10.4045/tidsskr.10.0217, PubMed 20348994
Publications 2009
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[Molecular diagnosis of malignant lymphomas]
Tidsskr Nor Laegeforen, 129 (22), 2352-6
DOI 10.4045/tidsskr.09.0704, PubMed 19935935 -
Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion
Blood, 114 (16), 3431-8
DOI 10.1182/blood-2009-05-223958, PubMed 19641184 -
c-Met signaling promotes IL-6-induced myeloma cell proliferation
Eur J Haematol, 82 (4), 277-87
DOI 10.1111/j.1600-0609.2009.01212.x, PubMed 19187270 -
Array-based DNA methylation profiling in follicular lymphoma
Leukemia, 23 (10), 1858-66
DOI 10.1038/leu.2009.114, PubMed 19587707
Publications 2008
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Bone marrow stroma cells regulate TIEG1 expression in acute lymphoblastic leukemia cells: role of TGFbeta/BMP-6 and TIEG1 in chemotherapy escape
Int J Cancer, 123 (12), 2759-66
DOI 10.1002/ijc.23833, PubMed 18798273 -
Oncogenic CARD11 mutations in human diffuse large B cell lymphoma
Science, 319 (5870), 1676-9
DOI 10.1126/science.1153629, PubMed 18323416 -
Stromal gene signatures in large-B-cell lymphomas
N Engl J Med, 359 (22), 2313-23
DOI 10.1056/NEJMoa0802885, PubMed 19038878 -
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways
Proc Natl Acad Sci U S A, 105 (36), 13520-5
DOI 10.1073/pnas.0804295105, PubMed 18765795 -
The presence of TP53 mutation at diagnosis of follicular lymphoma identifies a high-risk group of patients with shortened time to disease progression and poorer overall survival
Blood, 112 (8), 3126-9
DOI 10.1182/blood-2008-05-154013, PubMed 18628487
Publications 2007
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Expression of S100A4 by a variety of cell types present in the tumor microenvironment of human breast cancer
Int J Cancer, 121 (7), 1433-44
DOI 10.1002/ijc.22850, PubMed 17565747 -
Characterization of early stages of human B cell development by gene expression profiling
J Immunol, 179 (6), 3662-71
DOI 10.4049/jimmunol.179.6.3662, PubMed 17785802 -
Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma
J Exp Med, 204 (3), 633-43
DOI 10.1084/jem.20062041, PubMed 17353367 -
Inhibitory effects and target genes of bone morphogenetic protein 6 in Jurkat TAg cells
Eur J Immunol, 37 (10), 2937-48
DOI 10.1002/eji.200636759, PubMed 17899540 -
Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival
Blood, 109 (11), 4599-606
DOI 10.1182/blood-2006-08-039859, PubMed 17299095 -
Non-Hodgkin lymphoma with t(14;18): clonal evolution patterns and cytogenetic-pathologic-clinical correlations
J Cancer Res Clin Oncol, 133 (7), 455-70
DOI 10.1007/s00432-006-0188-3, PubMed 17235551
Publications 2006
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Molecular diagnosis of Burkitt's lymphoma
N Engl J Med, 354 (23), 2431-42
DOI 10.1056/NEJMoa055759, PubMed 16760443 -
BMP-6 inhibits human bone marrow B lymphopoiesis--upregulation of Id1 and Id3
Exp Hematol, 34 (1), 72-81
DOI 10.1016/j.exphem.2005.09.010, PubMed 16413393 -
Wnt3A activates canonical Wnt signalling in acute lymphoblastic leukaemia (ALL) cells and inhibits the proliferation of B-ALL cell lines
Br J Haematol, 136 (3), 400-13
DOI 10.1111/j.1365-2141.2006.06442.x, PubMed 17156404 -
Signaling through toll-like receptor 7/8 induces the differentiation of human bone marrow CD34+ progenitor cells along the myeloid lineage
J Mol Biol, 364 (5), 945-54
DOI 10.1016/j.jmb.2006.09.054, PubMed 17049554 -
Gain of chromosome 6p is an infrequent cause of increased PIM1 expression in B-cell non-Hodgkin's lymphomas
Leukemia, 20 (3), 539-42
DOI 10.1038/sj.leu.2404094, PubMed 16437153 -
PI3K/Akt-dependent Epo-induced signalling and target genes in human early erythroid progenitor cells
Br J Haematol, 135 (1), 117-28
DOI 10.1111/j.1365-2141.2006.06252.x, PubMed 16965383 -
Molecular biology on the ICU. From understanding to treating sepsis
Minerva Anestesiol, 72 (5), 255-67
PubMed 16675935 -
Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease
Genes Immun, 7 (1), 11-8
DOI 10.1038/sj.gene.6364263, PubMed 16222343
Publications 2005
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Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression-based survival prediction
Blood, 106 (9), 3183-90
DOI 10.1182/blood-2005-04-1399, PubMed 16046532 -
Translocation t(14;18) and gain of chromosome 18/BCL2: effects on BCL2 expression and apoptosis in B-cell non-Hodgkin's lymphomas
Leukemia, 19 (12), 2313-23
DOI 10.1038/sj.leu.2403954, PubMed 16193090 -
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1
BMC Immunol, 6, 9
DOI 10.1186/1471-2172-6-9, PubMed 15877825 -
[Matrix metalloproteinases and their inhibitors in lung cancer with malignant pleural effusion]
Pneumologie, 59 (8), 523-8
DOI 10.1055/s-2005-870966, PubMed 16110415 -
Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization
Oncogene, 24 (7), 1159-73
DOI 10.1038/sj.onc.1208267, PubMed 15580290 -
PU.1 protein expression has a positive linear association with protein expression of germinal centre B cell genes including BCL-6, CD10, CD20 and CD22: identification of PU.1 putative binding sites in the BCL-6 promotor
J Pathol, 206 (3), 312-9
DOI 10.1002/path.1777, PubMed 15892171
Publications 2004
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Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells
N Engl J Med, 351 (21), 2159-69
DOI 10.1056/NEJMoa041869, PubMed 15548776 -
Serological cloning of cancer/testis antigens expressed in prostate cancer using cDNA phage surface display
Cancer Immunol Immunother, 53 (5), 431-8
DOI 10.1007/s00262-003-0458-8, PubMed 14747957 -
NY-ESO-1 protein expression and humoral immune responses in prostate cancer
Prostate, 59 (4), 440-7
DOI 10.1002/pros.20025, PubMed 15065093 -
Gene expression analysis of peripheral T cells in a subgroup of common variable immunodeficiency shows predominance of CCR7(-) effector-memory T cells
Clin Exp Immunol, 138 (2), 278-89
DOI 10.1111/j.1365-2249.2004.02630.x, PubMed 15498038 -
Analysis of the autoantibody repertoire in Burkitt's lymphoma patients: frequent response against the transcription factor ATF-2
Cancer Immunol Immunother, 53 (12), 1119-26
DOI 10.1007/s00262-004-0558-0, PubMed 15185015 -
Adapting email functionality for mobile terminals
LECT NOTES COMPUT SC, 3283, 199-206 -
Plasma levels of transforming growth factor-1beta and alpha2-macroglobulin before and after radical prostatectomy: association to clinicopathological parameters
Prostate, 61 (3), 201-8
DOI 10.1002/pros.20062, PubMed 15368477
Publications 2003
-
Human alpha2-macroglobulin: genotype-phenotype relation
Exp Neurol, 184 (1), 153-61
DOI 10.1016/s0014-4886(03)00110-9, PubMed 14637088 -
Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma
J Exp Med, 198 (6), 851-62
DOI 10.1084/jem.20031074, PubMed 12975453 -
The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma
Cancer Cell, 3 (2), 185-97
DOI 10.1016/s1535-6108(03)00028-x, PubMed 12620412
Publications 2002
-
Activation of phosphatidylinositol 3-kinase is important for erythropoietin-induced erythropoiesis from CD34(+) hematopoietic progenitor cells
Exp Hematol, 30 (9), 990-1000
DOI 10.1016/s0301-472x(02)00868-8, PubMed 12225790 -
The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma
N Engl J Med, 346 (25), 1937-47
DOI 10.1056/NEJMoa012914, PubMed 12075054 -
Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study
BMC Bioinformatics, 3, 36
DOI 10.1186/1471-2105-3-36, PubMed 12445336
Publications 2001
-
High-dose therapy in patients with Hodgkin's disease: the use of selected CD34(+) cells is as safe as unmanipulated peripheral blood progenitor cells
Bone Marrow Transplant, 28 (9), 849-57
DOI 10.1038/sj.bmt.1703244, PubMed 11781645 -
Occurrence of matrix metalloproteinases and tissue inhibitors of metalloproteinases in tuberculous pleuritis
Tuberculosis (Edinb), 81 (3), 203-9
DOI 10.1054/tube.2000.0276, PubMed 11466032 -
[Gene therapy in cancer]
Tidsskr Nor Laegeforen, 121 (4), 482-8
PubMed 11255868 -
[Gene therapy--status and recommendations in Norwegian health care system]
Tidsskr Nor Laegeforen, 121 (3), 343-8
PubMed 11242880 -
Loss of chromosome 11q21-23.1 and 17p and gain of chromosome 6p are independent prognostic indicators in B-cell non-Hodgkin's lymphoma
Br J Cancer, 85 (12), 1900-13
DOI 10.1054/bjoc.2001.2164, PubMed 11747333
Publications 2000
-
Identification of nucleolar protein No55 as a tumour-associated autoantigen in patients with prostate cancer
Br J Cancer, 83 (6), 743-9
DOI 10.1054/bjoc.2000.1365, PubMed 10952778 -
Differential expression of bcl-2 homologs in human CD34(+) hematopoietic progenitor cells induced to differentiate into erythroid or granulocytic cells
Stem Cells, 18 (4), 261-72
DOI 10.1634/stemcells.18-4-261, PubMed 10924092 -
Protein kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation of CD34(+) progenitor cells from human bone marrow
Blood, 95 (2), 510-8
DOI 10.1182/blood.V95.2.510, PubMed 10627456 -
cAMP-mediated growth inhibition of lymphoid cells in G1: rapid down-regulation of cyclin D3 at the level of translation
Eur J Immunol, 30 (6), 1757-68
DOI 10.1002/1521-4141(200006)30:6<1757::AID-IMMU1757>3.0.CO;2-N, PubMed 10898514 -
Oncogenic aberrations in the p53 pathway are associated with a high S phase fraction and poor patient survival in B-cell Non-Hodgkin's lymphoma
Int J Cancer, 89 (4), 313-24
DOI 10.1002/1097-0215(20000720)89:4<313::aid-ijc1>3.0.co;2-d, PubMed 10956404 -
A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes
Blood, 95 (1), 221-30
DOI 10.1182/blood.V95.1.221.001k01_221_230, PubMed 10607706
Publications 1999
-
Evaluation of lymphoid cell populations in cytology specimens using flow cytometry and polymerase chain reaction
Diagn Mol Pathol, 8 (4), 183-8
DOI 10.1097/00019606-199912000-00003, PubMed 10617274 -
Relation between S-phase fraction of myeloma cells and anemia in patients with multiple myeloma
Exp Hematol, 27 (11), 1621-6
DOI 10.1016/s0301-472x(99)00105-8, PubMed 10560909 -
Prognostic value of lymphoma-specific S-phase fraction compared with that of other cell proliferation markers
Acta Oncol, 38 (4), 495-503
DOI 10.1080/028418699432040, PubMed 10418718 -
Retinoic acid induces apoptosis of human CD34+ hematopoietic progenitor cells: involvement of retinoic acid receptors and retinoid X receptors depends on lineage commitment of the hematopoietic progenitor cells
Exp Hematol, 27 (4), 642-53
DOI 10.1016/s0301-472x(98)00073-3, PubMed 10210322 -
Fas ligand promotes cell survival of immature human bone marrow CD34+CD38- hematopoietic progenitor cells by suppressing apoptosis
Exp Hematol, 27 (9), 1451-9
DOI 10.1016/s0301-472x(99)00073-9, PubMed 10480436 -
Activation of the cAMP signaling pathway increases apoptosis in human B-precursor cells and is associated with downregulation of Mcl-1 expression
J Cell Physiol, 180 (1), 71-80
DOI 10.1002/(SICI)1097-4652(199907)180:1<71::AID-JCP8>3.0.CO;2-N, PubMed 10362019 -
Lovastatin inhibits G1/S transition of normal human B-lymphocytes independent of apoptosis
Exp Cell Res, 252 (1), 144-53
DOI 10.1006/excr.1999.4608, PubMed 10502407 -
[University function at the central hospital in Akershus]
Tidsskr Nor Laegeforen, 119 (11), 1647
PubMed 10385812
Publications 1998
-
Combination chemotherapy with mitoguazon, ifosfamide, MTX, etoposide (MIME) and G-CSF can efficiently mobilize PBPC in patients with Hodgkin's and non-Hodgkin's lymphoma
Bone Marrow Transplant, 21 (9), 873-8
DOI 10.1038/sj.bmt.1701192, PubMed 9613778 -
[Molecular genetic diagnosis of leukemias and lymphomas]
Tidsskr Nor Laegeforen, 118 (16), 2511-8
PubMed 9667131 -
[Chronic lymphatic leukemia. Immunophenotyping as an aid to correct diagnosis]
Tidsskr Nor Laegeforen, 118 (2), 233-7
PubMed 9485618 -
RAR-, not RXR, ligands inhibit cell activation and prevent apoptosis in B-lymphocytes
J Cell Physiol, 175 (1), 68-77
DOI 10.1002/(SICI)1097-4652(199804)175:1<68::AID-JCP8>3.0.CO;2-A, PubMed 9491782 -
Generation and characterization of gp100 peptide-specific NK-T cell clones
Int J Cancer, 75 (5), 794-803
DOI 10.1002/(sici)1097-0215(19980302)75:5<794::aid-ijc21>3.0.co;2-5, PubMed 9495251 -
A simplified procedure for the isolation of immunoglobulins from human serum using a novel type of thiophilic gel at low salt concentration
J Immunol Methods, 219 (1-2), 109-18
DOI 10.1016/s0022-1759(98)00132-x, PubMed 9831392 -
Salt-independent binding of antibodies from human serum to thiophilic heterocyclic ligands
J Chromatogr B Biomed Sci Appl, 709 (2), 189-96
DOI 10.1016/s0378-4347(98)00109-1, PubMed 9657215 -
Proliferation and apoptosis in malignant and normal cells in B-cell non-Hodgkin's lymphomas
Br J Cancer, 77 (11), 1832-8
DOI 10.1038/bjc.1998.304, PubMed 9667654 -
Tumour cell proliferation, but not apoptosis, predicts survival in B-cell non-Hodgkin's lymphomas
Br J Cancer, 77 (11), 1839-41
DOI 10.1038/bjc.1998.305, PubMed 9667655
Publications 1997
-
Involvement of ICE (Caspase) family in gamma-radiation-induced apoptosis of normal B lymphocytes
Scand J Immunol, 46 (6), 601-8
DOI 10.1046/j.1365-3083.1997.d01-173.x, PubMed 9420624 -
A novel putative G-protein-coupled receptor expressed in lung, heart and lymphoid tissue
FEBS Lett, 407 (1), 59-62
DOI 10.1016/s0014-5793(97)00278-0, PubMed 9141481 -
Interleukin-13 in combination with CD40 ligand potently inhibits apoptosis in human B lymphocytes: upregulation of Bcl-xL and Mcl-1
Blood, 89 (12), 4415-24
PubMed 9192766 -
CDw78--a determinant on a major histocompatibility complex class II subpopulation that can be induced to associate with the cytoskeleton
Eur J Immunol, 27 (12), 3206-13
DOI 10.1002/eji.1830271218, PubMed 9464807 -
[Changing physician's role]
Tidsskr Nor Laegeforen, 117 (29), 4290
PubMed 9441481 -
Characterization, expression and chromosomal localization of a human gene homologous to the mouse Lsc oncogene, with strongest expression in hematopoetic tissues
Oncogene, 14 (14), 1747-52
DOI 10.1038/sj.onc.1200994, PubMed 9135076
Publications 1996
-
[High-dose therapy of cancer with CD34 positive cells as stem cell support]
Tidsskr Nor Laegeforen, 116 (21), 2542-6
PubMed 8928121 -
Purging of tumor cells from leukapheresis products: experimental and clinical aspects
J Hematother, 5 (4), 427-36
DOI 10.1089/scd.1.1996.5.427, PubMed 8877718 -
Cyclic AMP-dependent protein kinase (cAK) in human B cells: co-localization of type I cAK (RI alpha 2 C2) with the antigen receptor during anti-immunoglobulin-induced B cell activation
Eur J Immunol, 26 (6), 1290-6
DOI 10.1002/eji.1830260617, PubMed 8647207 -
Expression of the Bcl-2 homologue Mcl-1 correlates with survival of peripheral blood B lymphocytes
Cancer Res, 56 (1), 40-3
PubMed 8548771 -
The RAR-RXR as well as the RXR-RXR pathway is involved in signaling growth inhibition of human CD34+ erythroid progenitor cells
Blood, 87 (5), 1728-36
PubMed 8634418 -
Solid-phase method for differential display of genes expressed in hematopoietic stem cells
Biotechniques, 21 (1), 114-21
DOI 10.2144/96211rr02, PubMed 8816245 -
Arterial gene therapy
Lancet, 348 (9038), 1380-1; author reply 1381-2
DOI 10.1016/S0140-6736(05)65442-6, PubMed 8918290 -
Gene transfer mediated by alpha2-macroglobulin
Nucleic Acids Res, 24 (19), 3873-4
DOI 10.1093/nar/24.19.3873, PubMed 8871570
Publications 1995
-
Semiquantitative polymerase chain reaction for t(14;18) in follicular lymphomas: a colorimetric approach
Lab Invest, 72 (4), 411-8
PubMed 7723279 -
All-trans- and 9-cis-retinoic acid inhibit growth of normal human and murine B cell precursors
J Immunol, 155 (1), 58-65
PubMed 7602122 -
TGF-beta 1 and cyclic AMP promote apoptosis in resting human B lymphocytes
J Immunol, 154 (4), 1634-43
PubMed 7836748 -
[Physicians liable for military service for sale]
Tidsskr Nor Laegeforen, 115 (24), 3072
PubMed 7570542 -
Characterization of a promoter region supporting transcription of a novel human beta-galactoside alpha-2,6-sialyltransferase transcript in HepG2 cells
Biochim Biophys Acta, 1261 (1), 166-9
DOI 10.1016/0167-4781(94)00250-7, PubMed 7893756
Publications 1994
-
Retinoblastoma protein is rapidly dephosphorylated by elevated cyclic adenosine monophosphate levels in human B-lymphoid cells
Cancer Res, 54 (8), 2245-50
PubMed 8174134 -
Role of the 75-kDa tumor necrosis factor receptor: inhibition of early hematopoiesis
Proc Natl Acad Sci U S A, 91 (22), 10695-9
DOI 10.1073/pnas.91.22.10695, PubMed 7524102 -
All-trans- and 9-cis-retinoic acid: potent direct inhibitors of primitive murine hematopoietic progenitors in vitro
J Exp Med, 179 (5), 1665-70
DOI 10.1084/jem.179.5.1665, PubMed 8163945 -
Autologous bone marrow transplantation of non-Hodgkin's lymphoma patients with marrow purged using immunomagnetic beads
Prog Clin Biol Res, 389, 133-8
PubMed 7700895 -
[Bone marrow transplantation--a constantly developing procedure--requiring updating]
Tidsskr Nor Laegeforen, 114 (3), 302-3
PubMed 8191422 -
Cross-linking of CD53 promotes activation of resting human B lymphocytes
J Immunol, 153 (11), 4997-5007
PubMed 7963560 -
Bifunctional effects of tumor necrosis factor alpha (TNF alpha) on the growth of mature and primitive human hematopoietic progenitor cells: involvement of p55 and p75 TNF receptors
Blood, 83 (11), 3152-9
PubMed 7514902 -
Functional differences between CD38- and DR- subfractions of CD34+ bone marrow cells
Blood, 84 (5), 1473-81
PubMed 7520773 -
Tumor necrosis factor-alpha inhibits stem cell factor-induced proliferation of human bone marrow progenitor cells in vitro. Role of p55 and p75 tumor necrosis factor receptors
J Clin Invest, 94 (1), 165-72
DOI 10.1172/JCI117303, PubMed 7518828 -
All-trans retinoic acid directly inhibits granulocyte colony-stimulating factor-induced proliferation of CD34+ human hematopoietic progenitor cells
Blood, 84 (9), 2940-5
DOI 10.1182/blood.V84.9.2940.bloodjournal8492940, PubMed 7524761 -
A simple subtraction method for the isolation of cell-specific genes using magnetic monodisperse polymer particles
Biotechniques, 16 (4), 716-21
PubMed 8024795 -
Tissue specific expression and cDNA structure of a human transcript encoding a nucleic acid binding [oligo(dC)] protein related to the pre-mRNA binding protein K
Nucleic Acids Res, 22 (6), 959-64
DOI 10.1093/nar/22.6.959, PubMed 8152927
Publications 1993
-
Constitutive expression of c-myc does not relieve cAMP-mediated growth arrest in human lymphoid Reh cells
J Cell Physiol, 157 (1), 61-9
DOI 10.1002/jcp.1041570108, PubMed 8408242 -
Expression of CD18 (integrin beta 2 chain) correlates with prognosis in malignant B cell lymphomas
Br J Haematol, 83 (3), 392-8
DOI 10.1111/j.1365-2141.1993.tb04662.x, PubMed 8097923 -
Cytotoxic lymphocyte maturation factor (interleukin 12) is a synergistic growth factor for hematopoietic stem cells
J Exp Med, 178 (2), 413-8
DOI 10.1084/jem.178.2.413, PubMed 7688022 -
Leukemic blasts with markers of four cell lineages in Down's syndrome ("megakaryoblastic leukemia")
Med Pediatr Oncol, 21 (4), 254-8
DOI 10.1002/mpo.2950210404, PubMed 8469219 -
Cell-specific expression of human beta-galactoside alpha 2,6-sialyltransferase transcripts differing in the 5' untranslated region
Eur J Biochem, 213 (1), 467-75
DOI 10.1111/j.1432-1033.1993.tb17783.x, PubMed 8477718
Publications 1992
-
Vitamin A is a key regulator for cell growth, cytokine production, and differentiation in normal B cells
J Biol Chem, 267 (33), 23988-92
PubMed 1429735 -
Cell cycle-dependent regulation of CDw75 (beta-galactoside alpha-2,6-sialyltransferase) on human B lymphocytes
Eur J Immunol, 22 (5), 1149-55
DOI 10.1002/eji.1830220507, PubMed 1577059 -
Glucose-induced regulatory defects in the Saccharomyces cerevisiae byp1 growth initiation mutant and identification of MIG1 as a partial suppressor
J Bacteriol, 174 (12), 4183-8
DOI 10.1128/jb.174.12.4183-4188.1992, PubMed 1597433 -
A new method for detachment of Dynabeads from positively selected B lymphocytes
J Immunol Methods, 146 (2), 195-202
DOI 10.1016/0022-1759(92)90228-l, PubMed 1371532 -
Isolation and characterization of human hematopoietic progenitor cells: an effective method for positive selection of CD34+ cells
Leukemia, 6 (8), 845-52
PubMed 1379314 -
Differential chromatin structure-dependent binding of 7-aminoactinomycin D in normal and malignant bone marrow hematopoietic cells
Cancer Res, 52 (18), 5007-12
PubMed 1516056
Publications 1991
-
Acute hepatotoxicity after high-dose methotrexate administration to rats
Pharmacol Toxicol, 69 (2), 132-9
DOI 10.1111/j.1600-0773.1991.tb01286.x, PubMed 1775433 -
The effect of vindesine on methotrexate hydroxylation in the rat
Biochem Pharmacol, 42 (8), 1561-8
DOI 10.1016/0006-2952(91)90425-5, PubMed 1930283 -
Inhibition of 7-hydroxymethotrexate formation by amsacrine
Cancer Chemother Pharmacol, 28 (5), 377-83
DOI 10.1007/BF00685693, PubMed 1914082 -
Use of size fractionation of in vitro-activated human B lymphocytes for studies of cell cycle-dependent growth regulation
Scand J Immunol, 33 (1), 51-60
DOI 10.1111/j.1365-3083.1991.tb02491.x, PubMed 1899949 -
Independent regulation of 55-kDa and 75-kDa tumor necrosis factor receptors during activation of human peripheral blood B lymphocytes
Eur J Immunol, 21 (4), 1033-7
DOI 10.1002/eji.1830210426, PubMed 1850359 -
Differential effects of interferon-gamma and low molecular weight BCGF on growth of human B lymphocytes; interferon-gamma prolongs the increased c-MYC mRNA levels after activation
Scand J Immunol, 33 (4), 365-73
DOI 10.1111/j.1365-3083.1991.tb01783.x, PubMed 1902001 -
Immunomagnetic isolation of NK and LAK cells
J Immunol Methods, 136 (1), 1-9
DOI 10.1016/0022-1759(91)90242-8, PubMed 1704900 -
Interleukin-7 differentiates a subgroup of acute lymphoblastic leukemias
Blood, 77 (11), 2445-50
PubMed 2039826 -
Retinyl esters in chylomicron remnants inhibit growth of myeloid and lymphoid leukaemic cells
Eur J Clin Invest, 21 (6), 574-9
DOI 10.1111/j.1365-2362.1991.tb01411.x, PubMed 1778218
Publications 1990
-
Functional properties of CD19+ B lymphocytes positively selected from buffy coats by immunomagnetic separation
Eur J Immunol, 20 (1), 201-6
DOI 10.1002/eji.1830200129, PubMed 1689662 -
Characterization of a new malignant human T-cell line (PFI-285) sensitive to ascorbic acid
Eur J Haematol, 44 (1), 9-17
DOI 10.1111/j.1600-0609.1990.tb00340.x, PubMed 2307225 -
A transient acidification linked to intracellular Ca2+ in anti-mu-stimulated human B-lymphocytes
Acta Physiol Scand, 138 (2), 221-7
DOI 10.1111/j.1748-1716.1990.tb08836.x, PubMed 1690498 -
Immunological typing of acute leukaemias by rosetting with immunomagnetic beads: comparison with immunofluorescence staining
Scand J Immunol, 31 (5), 567-73
DOI 10.1111/j.1365-3083.1990.tb02807.x, PubMed 2189214 -
The B cell antigen CD75 is a cell surface sialytransferase
J Exp Med, 172 (2), 641-3
DOI 10.1084/jem.172.2.641, PubMed 2373995
Publications 1989
-
[Experiences of immunologic phenotyping in acute leukemia]
Tidsskr Nor Laegeforen, 109 (4), 443-6
PubMed 2919374 -
[Gene technology in the prevention of cancer]
Tidsskr Nor Laegeforen, 109 (33), 3430-4
PubMed 2609305 -
Intracellular events associated with inhibition of B cell activation by monoclonal antibodies to HLA class II antigens
Eur J Immunol, 19 (7), 1221-5
DOI 10.1002/eji.1830190711, PubMed 2547623 -
Ki67 and 4F2 antigen expression as well as DNA synthesis predict survival at relapse/tumour progression in low-grade B-cell lymphoma
Int J Cancer, 44 (6), 975-80
DOI 10.1002/ijc.2910440605, PubMed 2606582 -
Levels of myc protein, as analyzed by flow cytometry, correlate with cell growth potential in malignant B-cell lymphomas
Int J Cancer, 43 (1), 164-70
DOI 10.1002/ijc.2910430130, PubMed 2642893 -
Interleukin 4 induces selective production of interleukin 6 from normal human B lymphocytes
J Exp Med, 170 (4), 1463-8
DOI 10.1084/jem.170.4.1463, PubMed 2677211 -
[The 1989 Nobel Prize in physiology and medicine]
Tidsskr Nor Laegeforen, 109 (34-36), 3541-2
PubMed 2694425
Publications 1988
-
Triggering of neoplastic B cells via surface IgM and the cell surface antigens CD20 and CDw40. Responses differ from normal blood B cells and are restricted to certain morphologic subsets
Int J Cancer, 42 (4), 521-8
DOI 10.1002/ijc.2910420409, PubMed 2459071 -
cAMP-mediated growth inhibition of a B-lymphoid precursor cell line Reh is associated with an early transient delay in G2/M, followed by an accumulation of cells in G1
J Cell Physiol, 137 (3), 583-7
DOI 10.1002/jcp.1041370327, PubMed 2848044 -
Cyclic AMP has the ability to influence multiple events during B cell stimulation
Eur J Immunol, 18 (9), 1359-66
DOI 10.1002/eji.1830180909, PubMed 2458941 -
The use of separated subunits of yeast phosphofructokinase for the isolation of subunit-specific antibodies from polyclonal antisera
Biomed Biochim Acta, 47 (7), 705-11
PubMed 2974282 -
[The immunoglobulin gene superfamily]
Tidsskr Nor Laegeforen, 108 (13), 1029-32, 1004
PubMed 2455362 -
[Cellular oncogenes. Role in normal cell growth and activation in neoplasms]
Tidsskr Nor Laegeforen, 108 (16), 1299-303
PubMed 3291192 -
Retinol bound to physiological carrier molecules regulates growth and differentiation of myeloid leukemic cells
J Biol Chem, 263 (18), 8691-5
PubMed 3163997
Publications 1987
-
Epstein-Barr virus mediates a switch in responsiveness to transforming growth factor, type beta, in cells of the B cell lineage
Eur J Immunol, 17 (2), 299-301
DOI 10.1002/eji.1830170224, PubMed 3030769 -
Cyclic AMP-mediated suppression of normal and neoplastic B cell proliferation is associated with regulation of myc and Ha-ras protooncogenes
J Cell Physiol, 131 (3), 426-33
DOI 10.1002/jcp.1041310315, PubMed 3036888 -
The activation-associated antigen 4F2 predicts patient survival in low-grade B-cell lymphomas
Int J Cancer, 39 (5), 590-4
DOI 10.1002/ijc.2910390508, PubMed 3106247 -
Downregulation of c-myc RNA is not a prerequisite for reduced cell proliferation, but is associated with G1 arrest in B-lymphoid cell lines
Exp Cell Res, 172 (1), 84-91
DOI 10.1016/0014-4827(87)90095-4, PubMed 3115797 -
[Cerebrospinal fluid and plasma aminograms in patients with primary and secondary tumors of the CNS]
Infusionsther Klin Ernahr, 14 (2), 73-7
PubMed 3610311 -
Activation of human B cells: alternate options for initial triggering and effects of nonmitogenic concentrations of anti-IgM antibodies on resting and activated cells
J Immunol, 138 (10), 3179-84
PubMed 3553323 -
Transforming growth factor type beta (TGF beta) inhibits G1 to S transition, but not activation of human B lymphocytes
Exp Cell Res, 171 (1), 213-22
DOI 10.1016/0014-4827(87)90264-3, PubMed 2442015
Publications 1986
-
Effect of near normoglycaemia for two years on progression of early diabetic retinopathy, nephropathy, and neuropathy: the Oslo study
Br Med J (Clin Res Ed), 293 (6556), 1195-9
DOI 10.1136/bmj.293.6556.1195, PubMed 3096429 -
Characterization of human mononuclear cells after positive selection with immunomagnetic particles
Scand J Immunol, 23 (4), 509-19
DOI 10.1111/j.1365-3083.1986.tb03083.x, PubMed 2422741 -
IgG subclasses in lymphomas
Monogr Allergy, 19, 164-8
PubMed 3762542 -
Regulation of c-myc mRNA and protein levels during activation of normal human B cells
Curr Top Microbiol Immunol, 132, 290-6
DOI 10.1007/978-3-642-71562-4_43, PubMed 3539537
Publications 1985
-
Analyses of maximum cardiopulmonary performance during exposure to acute hypoxia at simulated altitude--sea level to 5000 meters (760-404 mm Hg)
Aviat Space Environ Med, 56 (12), 1192-7
PubMed 4084174 -
Antibodies to surface IgM and IgD increase the expression of various class II antigens on human B cells
Eur J Immunol, 15 (2), 173-7
DOI 10.1002/eji.1830150212, PubMed 3871699 -
Intracellular Ca2+ buffering potentiates an 86Rb+ permeability response in human lymphocytes
Acta Physiol Scand, 124 (2), 247-51
DOI 10.1111/j.1748-1716.1985.tb07658.x, PubMed 3925725 -
Characterization of two murine monoclonal antibodies reactive with human B cells. Their use in a high-yield, high-purity method for isolation of B cells and utilization of such cells in an assay for B-cell stimulating factor
Scand J Immunol, 21 (3), 205-14
DOI 10.1111/j.1365-3083.1985.tb01422.x, PubMed 3887557 -
The specific induction of myc protooncogene expression in normal human B cells is not a sufficient event for acquisition of competence to proliferate
Proc Natl Acad Sci U S A, 82 (18), 6255-9
DOI 10.1073/pnas.82.18.6255, PubMed 3929253
Publications 1984
-
Thyroid antibodies in blood donors: prevalence and clinical significance
Acta Endocrinol (Copenh), 105 (3), 324-9
DOI 10.1530/acta.0.1050324, PubMed 6702401 -
Direct two-site binding enzyme immunoassay for human alpha-1-fetoprotein. Part I: Comparison of different peroxidase-IgG-conjugates and various reaction conditions
Z Med Lab Diagn, 25 (1), 5-13
PubMed 6202071 -
Surface IgG subclasses in human B cell lymphomas as revealed by monoclonal antibodies
Clin Exp Immunol, 57 (1), 163-70
PubMed 6378459 -
Modification of the 'dividing bradycardia' by hypoxia or exercise
Respir Physiol, 56 (2), 245-51
DOI 10.1016/0034-5687(84)90108-7, PubMed 6463431
Publications 1983
-
A novel purification procedure for human alpha-fetoprotein by application of immobilised Cibacron Blue F3G-A as affinity ligand
Clin Chim Acta, 133 (3), 335-40
DOI 10.1016/0009-8981(83)90280-2, PubMed 6194922 -
Interactions of antibodies against soluble phosphofructokinase with the soluble and particulate enzymes from yeast
FEBS Lett, 155 (1), 50-4
DOI 10.1016/0014-5793(83)80207-5, PubMed 6220923
Publications 1982
-
A new procedure for the purification of proteinase B from baker's yeast and interaction of the purified enzyme with a specific inhibitor
Acta Biol Med Ger, 41 (11), 991-1002
PubMed 6763433
Publications 1981
-
[Anaesthesia and diabetes insipidus. A review (author's transl)]
Anaesthesist, 30 (4), 159-65
PubMed 7018319
Publications 1980
-
[Circulatory changes in neurosurgical patients with intracerebral angiomas in neuroleptanaesthesia (author's transl)]
Anasth Intensivther Notfallmed, 15 (2), 144-51
PubMed 7396101 -
[Circulatory effects of dihydrazinophthalazine (Nepresol) compared with sodium nitroprusside in controlled hypotension. A study of neurosurgical patients under neuroleptanesthesia]
Anasth Intensivther Notfallmed, 15 (2), 152-8
PubMed 6772047 -
[Clinical experiences with diazepam (Valium) - fentanyl combination anesthesia in neurosurgery. A study of circulation and oxygen consumption]
Anasth Intensivther Notfallmed, 15 (2), 135-43
PubMed 6772046
Publications 1979
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[Exacerbation of systemic lupus erythematosus following UV irradiation--a hypothesis]
Acta Biol Med Ger, 38 (9), 1301-6
PubMed 399148 -
[Circulatory changes in the sitting position during neurosurgical anaesthesia (NLA) (author's transl)]
Anaesthesist, 28 (12), 557-63
PubMed 539650
Publications 1978
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[The effect of buprenorphin on circulation, respiration and the electroencephalogram (a postoperative study of 12 neurosurgical cases) (author's transl)]
Prakt Anaesth, 13 (6), 489-94
PubMed 740629
Publications 1977
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[Exacerbation of lupus erythematodes visceralis due to UV irradiation. Results and hypothetical aspects]
Dermatol Monatsschr, 163 (4), 290-5
PubMed 881079
Publications 1976
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Differences in the degradation of yeast phosphofructokinase by proteinases A and B from yeast
Biochem J, 155 (3), 721-3
DOI 10.1042/bj1550721, PubMed 133676 -
[Cardiovascular changes caused by atropine in normo- and hypothermic methoxyflurane anaesthesia (author's transl)]
Anaesthesist, 25 (9), 418-24
PubMed 970597
Publications 1974
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[The effects of naloxone (Narcan) on circulation and respiration after neurolept anaesthesia for neurosurgical operations (author's transl)]
Anaesthesist, 23 (11), 493-9
PubMed 4458474 -
[Changes of the pah-plasma levels as a guideline for the renal circulation under the influence of various anaesthetic agents (author's transl)]
Anaesthesist, 23 (1), 5-9
PubMed 4458471
Publications 1972
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[Changes of lactic and pyruvic acid levels in the cerebrospinal fluid as possible indicators for central hypoxia. Studies in hydrocephalic children]
Neurochirurgia (Stuttg), 15 (6), 194-200
DOI 10.1055/s-0028-1090542, PubMed 4655985 -
[Hemodynamic changes in methoxyflurane anesthesia with controlled hypotension and hypothermia for neurosurgery]
Zentralbl Neurochir, 33 (1), 19-33
PubMed 5072148