Publications from OUS - Immunotherapy against solid cancers (Kyte)
74 publications found
Publications 2024
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Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors - a biomarker analysis of the ALICE and ICON trials
Mol Oncol (in press)
DOI 10.1002/1878-0261.13675, PubMed 38978352 -
Ipilimumab and nivolumab combined with anthracycline-based chemotherapy in metastatic hormone receptor-positive breast cancer: a randomized phase 2b trial
J Immunother Cancer, 12 (1)
DOI 10.1136/jitc-2023-007990, PubMed 38242720 -
Peripheral immune cells in metastatic breast cancer patients display a systemic immunosuppressed signature consistent with chronic inflammation
NPJ Breast Cancer, 10 (1), 30
DOI 10.1038/s41523-024-00638-2, PubMed 38653982 -
Comparative Evaluation of STEAP1 Targeting Chimeric Antigen Receptors with Different Costimulatory Domains and Spacers
Int J Mol Sci, 25 (1)
DOI 10.3390/ijms25010586, PubMed 38203757 -
Correction: Jin et al. Comparative Evaluation of STEAP1 Targeting Chimeric Antigen Receptors with Different Costimulatory Domains and Spacers. Int. J. Mol. Sci. 2024, 25, 586
Int J Mol Sci, 25 (18)
DOI 10.3390/ijms251810024, PubMed 39337718 -
Plasma protein dynamics during ipilimumab treatment in metastatic melanoma: associations with tumor response, adverse events and survival
Oncoimmunology, 14 (1), 2440967
DOI 10.1080/2162402X.2024.2440967, PubMed 39703053 -
Gut microbiota diversity is prognostic and associated with benefit from chemo-immunotherapy in metastatic triple-negative breast cancer
Mol Oncol (in press)
DOI 10.1002/1878-0261.13760, PubMed 39545921 -
Changes in AXL and/or MITF melanoma subpopulations in patients receiving immunotherapy
Immunooncol Technol, 24, 101009
DOI 10.1016/j.iotech.2024.101009, PubMed 39697983
Publications 2023
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Development of a TGFβ-IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy
Biomedicines, 11 (2)
DOI 10.3390/biomedicines11020459, PubMed 36830995 -
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
J Allergy Clin Immunol, 152 (1), 278-289.e6
DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861 -
Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection
Eur J Immunol, 53 (8), e2250254
DOI 10.1002/eji.202250254, PubMed 37102399
Publications 2022
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Development of a High-Affinity Antibody against the Tumor-Specific and Hyperactive 611-p95HER2 Isoform
Cancers (Basel), 14 (19)
DOI 10.3390/cancers14194859, PubMed 36230782 -
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 225
DOI 10.1186/s12967-022-03432-5, PubMed 35568909 -
Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 317
DOI 10.1186/s12967-022-03518-0, PubMed 35841045 -
Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer
Mol Ther Oncolytics, 26, 189-206
DOI 10.1016/j.omto.2022.06.007, PubMed 35860008 -
Strategies for Improving the Efficacy of CAR T Cells in Solid Cancers
Cancers (Basel), 14 (3)
DOI 10.3390/cancers14030571, PubMed 35158839 -
Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction
J Infect Dis, 225 (4), 661-674
DOI 10.1093/infdis/jiaa714, PubMed 33216130 -
Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
J Acquir Immune Defic Syndr, 89 (1), 77-86
DOI 10.1097/QAI.0000000000002817, PubMed 34878437 -
Atezolizumab plus anthracycline-based chemotherapy in metastatic triple-negative breast cancer: the randomized, double-blind phase 2b ALICE trial
Nat Med, 28 (12), 2573-2583
DOI 10.1038/s41591-022-02126-1, PubMed 36482103 -
Health-related quality of life in patients with advanced melanoma treated with ipilimumab: prognostic implications and changes during treatment
ESMO Open, 7 (5), 100588
DOI 10.1016/j.esmoop.2022.100588, PubMed 36116420
Publications 2021
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Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4+ T Cells in HIV-Infected Immunological Non-Responders
Front Immunol, 12, 744155
DOI 10.3389/fimmu.2021.744155, PubMed 34691047
Publications 2020
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CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile
Mucosal Immunol, 14 (2), 402-410
DOI 10.1038/s41385-020-0315-5, PubMed 32572129 -
Use of RNA Interference with TCR Transfer to Enhance Safety and Efficiency
Methods Mol Biol, 2115, 327-349
DOI 10.1007/978-1-0716-0290-4_18, PubMed 32006409 -
Machine learning derived input-function in a dynamic 18F-FDG PET study of mice
Biomed Phys Eng Express, 6 (1), 015020
DOI 10.1088/2057-1976/ab6496, PubMed 33438608 -
ICON: a randomized phase IIb study evaluating immunogenic chemotherapy combined with ipilimumab and nivolumab in patients with metastatic hormone receptor positive breast cancer
J Transl Med, 18 (1), 269
DOI 10.1186/s12967-020-02421-w, PubMed 32620163 -
ALICE: a randomized placebo-controlled phase II study evaluating atezolizumab combined with immunogenic chemotherapy in patients with metastatic triple-negative breast cancer
J Transl Med, 18 (1), 252
DOI 10.1186/s12967-020-02424-7, PubMed 32576225
Publications 2019
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Resident memory CD8 T cells persist for years in human small intestine
J Exp Med, 216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737 -
Transient redirection of T cells for adoptive cell therapy with telomerase-specific T helper cell receptors isolated from long term survivors after cancer vaccination
Oncoimmunology, 8 (4), e1565236
DOI 10.1080/2162402X.2019.1565236, PubMed 30906659 -
Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery
AIDS, 33 (7), 1117-1129
DOI 10.1097/QAD.0000000000002173, PubMed 30789356
Publications 2017
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T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth
Oncoimmunology, 6 (4), e1302631
DOI 10.1080/2162402X.2017.1302631, PubMed 28507809
Publications 2016
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Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease
Clin Transl Immunology, 5 (11), e109
DOI 10.1038/cti.2016.65, PubMed 27990285 -
T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy
Oncoimmunology, 5 (12), e1249090
DOI 10.1080/2162402X.2016.1249090, PubMed 28123886 -
Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells
Oncoimmunology, 5 (11), e1232237
DOI 10.1080/2162402X.2016.1232237, PubMed 27999747
Publications 2012
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Widespread CD4+ T-cell reactivity to novel hTERT epitopes following vaccination of cancer patients with a single hTERT peptide GV1001
Oncoimmunology, 1 (5), 670-686
DOI 10.4161/onci.20426, PubMed 22934259
Publications 2011
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Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial
Clin Cancer Res, 17 (21), 6847-57
DOI 10.1158/1078-0432.CCR-11-1385, PubMed 21918169 -
Is secretion of tumour-specific antigen important for cancer eradication by CD4(+) T cells?--Implications for cancer immunotherapy by adoptive T cell transfer
Scand J Immunol, 73 (6), 527-30
DOI 10.1111/j.1365-3083.2011.02558.x, PubMed 21388431 -
Vaccination of patients with cutaneous melanoma with telomerase-specific peptides
Cancer Immunol Immunother, 60 (11), 1553-64
DOI 10.1007/s00262-011-1061-z, PubMed 21681371 -
Telomerase peptide vaccination combined with temozolomide: a clinical trial in stage IV melanoma patients
Clin Cancer Res, 17 (13), 4568-80
DOI 10.1158/1078-0432.CCR-11-0184, PubMed 21586625
Publications 2010
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Transiently redirected T cells for adoptive transfer
Cytotherapy, 13 (5), 629-40
DOI 10.3109/14653249.2010.542461, PubMed 21174490 -
[We know more than we can understand]
Tidsskr Nor Laegeforen, 130 (22), 2217
DOI 10.4045/tidsskr.10.1000, PubMed 21109831 -
Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection
PLoS Pathog, 6 (12), e1001227
DOI 10.1371/journal.ppat.1001227, PubMed 21187913
Publications 2009
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Secretion of tumor-specific antigen by myeloma cells is required for cancer immunosurveillance by CD4+ T cells
Cancer Res, 69 (14), 5901-7
DOI 10.1158/0008-5472.CAN-08-4816, PubMed 19567679 -
Unconventional cytokine profiles and development of T cell memory in long-term survivors after cancer vaccination
Cancer Immunol Immunother, 58 (10), 1609-26
DOI 10.1007/s00262-009-0670-2, PubMed 19221745
Publications 2008
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Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection
J Exp Med, 205 (9), 2111-24
DOI 10.1084/jem.20072076, PubMed 18695005 -
Bone marrow stroma cells regulate TIEG1 expression in acute lymphoblastic leukemia cells: role of TGFbeta/BMP-6 and TIEG1 in chemotherapy escape
Int J Cancer, 123 (12), 2759-66
DOI 10.1002/ijc.23833, PubMed 18798273 -
Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection
J Clin Invest, 118 (5), 1835-45
DOI 10.1172/JCI33402, PubMed 18398508 -
beta-catenin is involved in N-cadherin-dependent adhesion, but not in canonical Wnt signaling in E2A-PBX1-positive B acute lymphoblastic leukemia cells
Exp Hematol, 37 (2), 225-33
DOI 10.1016/j.exphem.2008.10.007, PubMed 19101069
Publications 2007
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Characterization of early stages of human B cell development by gene expression profiling
J Immunol, 179 (6), 3662-71
DOI 10.4049/jimmunol.179.6.3662, PubMed 17785802
Publications 2006
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Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
Cancer Immunol Immunother, 55 (12), 1553-64
DOI 10.1007/s00262-006-0145-7, PubMed 16491401 -
Wnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesis
BMC Immunol, 7, 13
DOI 10.1186/1471-2172-7-13, PubMed 16808837 -
BMP-6 inhibits human bone marrow B lymphopoiesis--upregulation of Id1 and Id3
Exp Hematol, 34 (1), 72-81
DOI 10.1016/j.exphem.2005.09.010, PubMed 16413393 -
Immuno-gene therapy of cancer with tumour-mRNA transfected dendritic cells
Cancer Immunol Immunother, 55 (11), 1432-42
DOI 10.1007/s00262-006-0161-7, PubMed 16612595 -
T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
Cancer Immunol Immunother, 56 (5), 659-75
DOI 10.1007/s00262-006-0222-y, PubMed 16947019 -
Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
Cancer Gene Ther, 13 (10), 905-18
DOI 10.1038/sj.cgt.7700961, PubMed 16710345 -
Wnt3A activates canonical Wnt signalling in acute lymphoblastic leukaemia (ALL) cells and inhibits the proliferation of B-ALL cell lines
Br J Haematol, 136 (3), 400-13
DOI 10.1111/j.1365-2141.2006.06442.x, PubMed 17156404
Publications 2005
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Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL
J Exp Med, 202 (8), 1109-19
DOI 10.1084/jem.20050162, PubMed 16216889 -
Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
Cancer Gene Ther, 12 (6), 579-91
DOI 10.1038/sj.cgt.7700837, PubMed 15818380 -
Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection
J Infect Dis, 191 (7), 1169-79
DOI 10.1086/428502, PubMed 15747254 -
Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
Br J Cancer, 93 (7), 749-56
DOI 10.1038/sj.bjc.6602761, PubMed 16136047 -
CD10+ stromal cells form B-lymphocyte maturation niches in the human bone marrow
J Pathol, 205 (3), 311-7
DOI 10.1002/path.1705, PubMed 15682430
Publications 2004
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Butyrate response factor 1 is regulated by parathyroid hormone and bone morphogenetic protein-2 in osteoblastic cells
Biochem Biophys Res Commun, 324 (1), 218-23
DOI 10.1016/j.bbrc.2004.09.030, PubMed 15465005
Publications 2003
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Molecular heterogeneity in human osteosarcoma demonstrated by enriched mRNAs isolated by directional tag PCR subtraction cloning
Anticancer Res, 23 (3B), 2201-16
PubMed 12894494 -
The human solute carrier SLC41A1 belongs to a novel eukaryotic subfamily with homology to prokaryotic MgtE Mg2+ transporters
Biochem Biophys Res Commun, 306 (3), 718-24
DOI 10.1016/s0006-291x(03)01030-1, PubMed 12810078
Publications 2002
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Inhibition of HLA-DR assembly, transport, and loading by human cytomegalovirus glycoprotein US3: a novel mechanism for evading major histocompatibility complex class II antigen presentation
J Virol, 76 (21), 10929-41
DOI 10.1128/jvi.76.21.10929-10941.2002, PubMed 12368336 -
Characterization of the novel human transmembrane protein 9 (TMEM9) that localizes to lysosomes and late endosomes
Biochem Biophys Res Commun, 297 (4), 912-7
DOI 10.1016/s0006-291x(02)02228-3, PubMed 12359240 -
Inhibition of glycolipid shedding rescues recognition of a CD1+ T cell lymphoma by natural killer T (NKT) cells
Proc Natl Acad Sci U S A, 99 (12), 8197-202
DOI 10.1073/pnas.122636199, PubMed 12060764
Publications 2001
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A signal sequence trap based on cell enrichment using anti-CD19 antibody coated magnetic beads
Scand J Immunol, 54 (3), 280-4
DOI 10.1046/j.1365-3083.2001.00925.x, PubMed 11555391
Publications 2000
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Ephrin-B2 is a candidate ligand for the Eph receptor, EphB6
FEBS Lett, 466 (1), 169-74
DOI 10.1016/s0014-5793(99)01793-7, PubMed 10648835 -
Sox-4 messenger RNA is expressed in the embryonic growth plate and regulated via the parathyroid hormone/parathyroid hormone-related protein receptor in osteoblast-like cells
J Bone Miner Res, 15 (12), 2402-12
DOI 10.1359/jbmr.2000.15.12.2402, PubMed 11127205
Publications 1999
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Two human osteoblast-like osteosarcoma cell lines show distinct expression and differential regulation of parathyroid hormone-related protein
J Bone Miner Res, 14 (6), 904-14
DOI 10.1359/jbmr.1999.14.6.904, PubMed 10352098 -
Structural and functional organization of the gene encoding the human thyrotropin-releasing hormone receptor
J Neurochem, 72 (1), 40-50
DOI 10.1046/j.1471-4159.1999.0720040.x, PubMed 9886052
Publications 1995
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Midmolecular parathyroid hormone-related peptide in serum during pregnancy, lactation and in umbilical cord blood
Eur J Endocrinol, 132 (4), 438-43
DOI 10.1530/eje.0.1320438, PubMed 7711881
Publications 1993
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G-PROTEIN COUPLED SIGNALING IN OSTEOSARCOMA CELL-LINES
FRONTIERS OF OSTEOSARCOMA RESEARCH: INTERDISCIPLINARY SURVEY OF CLINICAL AND RESEARCH ADVANCES, 297-302
Publications 1991
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[Malignant humoral hypercalcemia and the parathyroid hormone related protein]
Tidsskr Nor Laegeforen, 111 (14), 1738-42
PubMed 2063384