Yixin Jin

  • Researcher; PhD

Publications 2024

Jin Y, Dunn C, Persiconi I, Sike A, Skorstad G, Beck C, Kyte JA (2024)
Comparative Evaluation of STEAP1 Targeting Chimeric Antigen Receptors with Different Costimulatory Domains and Spacers
Int J Mol Sci, 25 (1)
DOI 10.3390/ijms25010586, PubMed 38203757

Publications 2023

Beck C, Casey NP, Persiconi I, Moharrami NN, Sike A, Jin Y, Kyte JA (2023)
Development of a TGFβ-IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy
Biomedicines, 11 (2)
DOI 10.3390/biomedicines11020459, PubMed 36830995

Publications 2022

Jin Y, Lorvik KB, Jin Y, Beck C, Sike A, Persiconi I, Kvaløy E, Saatcioglu F, Dunn C, Kyte JA (2022)
Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer
Mol Ther Oncolytics, 26, 189-206
DOI 10.1016/j.omto.2022.06.007, PubMed 35860008

Publications 2021

Pällmann N, Deng K, Livgård M, Tesikova M, Jin Y, Frengen NS, Kahraman N, Mokhlis HM, Ozpolat B, Kildal W, Danielsen HE, Fazli L, Rennie PS, Banerjee PP, Üren A, Jin Y, Kuzu OF, Saatcioglu F (2021)
Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression
Cancer Res, 81 (15), 4066-4078
DOI 10.1158/0008-5472.CAN-20-3956, PubMed 34183356

Publications 2019

Pällmann N, Livgård M, Tesikova M, Zeynep Nenseth H, Akkus E, Sikkeland J, Jin Y, Koc D, Kuzu OF, Pradhan M, Danielsen HE, Kahraman N, Mokhlis HM, Ozpolat B, Banerjee PP, Uren A, Fazli L, Rennie PS, Jin Y, Saatcioglu F (2019)
Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer
Oncogene, 38 (35), 6301-6318
DOI 10.1038/s41388-019-0879-2, PubMed 31312022

Publications 2016

Li J, Liu Y, Jin Y, Wang R, Wang J, Lu S, VanBuren V, Dostal DE, Zhang SL, Peng X (2016)
Essential role of Cdc42 in cardiomyocyte proliferation and cell-cell adhesion during heart development
Dev Biol, 421 (2), 271-283
DOI 10.1016/j.ydbio.2016.12.012, PubMed 27986432

Publications 2014

Zhou MH, Zheng H, Si H, Jin Y, Peng JM, He L, Zhou Y, Muñoz-Garay C, Zawieja DC, Kuo L, Peng X, Zhang SL (2014)
Stromal interaction molecule 1 (STIM1) and Orai1 mediate histamine-evoked calcium entry and nuclear factor of activated T-cells (NFAT) signaling in human umbilical vein endothelial cells
J Biol Chem, 289 (42), 29446-56
DOI 10.1074/jbc.M114.578492, PubMed 25190815

Publications 2013

Jin Y, Liu Y, Lin Q, Li J, Druso JE, Antonyak MA, Meininger CJ, Zhang SL, Dostal DE, Guan JL, Cerione RA, Peng X (2013)
Deletion of Cdc42 enhances ADAM17-mediated vascular endothelial growth factor receptor 2 shedding and impairs vascular endothelial cell survival and vasculogenesis
Mol Cell Biol, 33 (21), 4181-97
DOI 10.1128/MCB.00650-13, PubMed 23979594

Liu Y, Jin Y, Li J, Seto E, Kuo E, Yu W, Schwartz RJ, Blazo M, Zhang SL, Peng X (2013)
Inactivation of Cdc42 in neural crest cells causes craniofacial and cardiovascular morphogenesis defects
Dev Biol, 383 (2), 239-52
DOI 10.1016/j.ydbio.2013.09.013, PubMed 24056078

Zakrzewska M, Haugsten EM, Nadratowska-Wesolowska B, Oppelt A, Hausott B, Jin Y, Otlewski J, Wesche J, Wiedlocha A (2013)
ERK-mediated phosphorylation of fibroblast growth factor receptor 1 on Ser777 inhibits signaling
Sci Signal, 6 (262), ra11
DOI 10.1126/scisignal.2003087, PubMed 23405013

Publications 2012

Jin Y, Liu Y, Antonyak M, Peng X (2012)
Isolation and characterization of vascular endothelial cells from murine heart and lung
Methods Mol Biol, 843, 147-54
DOI 10.1007/978-1-61779-523-7_14, PubMed 22222529

Peng X, Lin Q, Liu Y, Jin Y, Druso JE, Antonyak MA, Guan JL, Cerione RA (2012)
Inactivation of Cdc42 in embryonic brain results in hydrocephalus with ependymal cell defects in mice
Protein Cell, 4 (3), 231-42
DOI 10.1007/s13238-012-2098-2, PubMed 23150167

Zhen Y, Sørensen V, Skjerpen CS, Haugsten EM, Jin Y, Wälchli S, Olsnes S, Wiedlocha A (2012)
Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnα1 and Kpnβ1
Traffic, 13 (5), 650-64
DOI 10.1111/j.1600-0854.2012.01341.x, PubMed 22321063

Publications 2011

Jin Y, Zhen Y, Haugsten EM, Wiedlocha A (2011)
The driver of malignancy in KG-1a leukemic cells, FGFR1OP2-FGFR1, encodes an HSP90 addicted oncoprotein
Cell Signal, 23 (11), 1758-66
DOI 10.1016/j.cellsig.2011.06.010, PubMed 21745565

Zakrzewska M, Sørensen V, Jin Y, Wiedlocha A, Olsnes S (2011)
Translocation of exogenous FGF1 into cytosol and nucleus is a periodic event independent of receptor kinase activity
Exp Cell Res, 317 (7), 1005-15
DOI 10.1016/j.yexcr.2011.01.003, PubMed 21223966

Publications 2007

Zhen Y, Sørensen V, Jin Y, Suo Z, Wiedłocha A (2007)
Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
Oncogene, 26 (44), 6372-85
DOI 10.1038/sj.onc.1210473, PubMed 17533378

Publications 2006

Oz-Arslan D, Rüscher W, Myrtek D, Ziemer M, Jin Y, Damaj BB, Sorichter S, Idzko M, Norgauer J, Maghazachi AA (2006)
IL-6 and IL-8 release is mediated via multiple signaling pathways after stimulating dendritic cells with lysophospholipids
J Leukoc Biol, 80 (2), 287-97
DOI 10.1189/jlb.1205751, PubMed 16769764

Publications 2005

Gauzzi MC, Purificato C, Donato K, Jin Y, Wang L, Daniel KC, Maghazachi AA, Belardelli F, Adorini L, Gessani S (2005)
Suppressive effect of 1alpha,25-dihydroxyvitamin D3 on type I IFN-mediated monocyte differentiation into dendritic cells: impairment of functional activities and chemotaxis
J Immunol, 174 (1), 270-6
DOI 10.4049/jimmunol.174.1.270, PubMed 15611249

Jin Y, Damaj BB, Maghazachi AA (2005)
Human resting CD16-, CD16+ and IL-2-, IL-12-, IL-15- or IFN-alpha-activated natural killer cells differentially respond to sphingosylphosphorylcholine, lysophosphatidylcholine and platelet-activating factor
Eur J Immunol, 35 (9), 2699-708
DOI 10.1002/eji.200526129, PubMed 16078278

Publications 2004

Maghazachi AA, Knudsen E, Jin Y, Jenstad M, Chaudhry FA (2004)
D-galactosyl-beta1-1'-sphingosine and D-glucosyl-beta1-1'-sphingosine induce human natural killer cell apoptosis
Biochem Biophys Res Commun, 320 (3), 810-5
DOI 10.1016/j.bbrc.2004.06.027, PubMed 15240120

Wang L, Knudsen E, Jin Y, Gessani S, Maghazachi AA (2004)
Lysophospholipids and chemokines activate distinct signal transduction pathways in T helper 1 and T helper 2 cells
Cell Signal, 16 (9), 991-1000
DOI 10.1016/j.cellsig.2004.02.001, PubMed 15212760

Publications 2003

Jin Y, Knudsen E, Wang L, Bryceson Y, Damaj B, Gessani S, Maghazachi AA (2003)
Sphingosine 1-phosphate is a novel inhibitor of T-cell proliferation
Blood, 101 (12), 4909-15
DOI 10.1182/blood-2002-09-2962, PubMed 12586615

Jin Y, Knudsen E, Wang L, Maghazachi AA (2003)
Lysophosphatidic acid induces human natural killer cell chemotaxis and intracellular calcium mobilization
Eur J Immunol, 33 (8), 2083-9
DOI 10.1002/eji.200323711, PubMed 12884281

Li Y, Jin Y, Chen H, Jie G, Tobelem G, Caen JP, Han ZC (2003)
Suppression of tumor growth by viral vector-mediated gene transfer of N-terminal truncated platelet factor 4
Cancer Biother Radiopharm, 18 (5), 829-40
DOI 10.1089/108497803770418373, PubMed 14629831

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