Publications from OUS - Cell Signaling and Immune Regulation (Kjetil Taskén)

56 publications found

Publications 2024

  1. Helland Å, Steinskog ESS, Blix ES, Flobak Å, Brabrand S, Puco K, Niehusmann P, Meltzer S, Oppedal IA, Haug Å, Torkildsen CF, Randen U, Gilje B, Lønning PE, Gjertsen BT, Hovland R, Russnes HG, Fagereng GL, Smeland S, Tasken K (2024)
    [Not Available]
    Tidsskr Nor Laegeforen, 144 (1)
    DOI 10.4045/tidsskr.23.0740, PubMed 38258713
  2. Montoya S, Bourcier J, Noviski M, Lu H, Thompson MC, Chirino A, Jahn J, Sondhi AK, Gajewski S, Tan YSM, Yung S, Urban A, Wang E, Han C, Mi X, Kim WJ, Sievers Q, Auger P, Bousquet H, Brathaban N, Bravo B, Gessner M, Guiducci C, Iuliano JN, Kane T et al. (2024)
    Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127
    Science, 383 (6682), eadi5798
    DOI 10.1126/science.adi5798, PubMed 38301010
  3. Sveen A, Johannessen B, Klokkerud SM, Kraggerud SM, Meza-Zepeda LA, Bjørnslett M, Bischof K, Myklebost O, Taskén K, Skotheim RI, Dørum A, Davidson B, Lothe RA (2024)
    Evolutionary mode and timing of dissemination of high-grade serous carcinomas
    JCI Insight, 9 (3)
    DOI 10.1172/jci.insight.170423, PubMed 38175731

Publications 2023

  1. Andersen AN, Brodersen AM, Ayuda-Durán P, Piechaczyk L, Tadele DS, Baken L, Fredriksen J, Stoksflod M, Lenartova A, Fløisand Y, Skånland SS, Enserink JM (2023)
    Clinical forecasting of acute myeloid leukemia using ex vivo drug-sensitivity profiling
    Cell Rep Methods, 3 (12), 100654
    DOI 10.1016/j.crmeth.2023.100654, PubMed 38065095
  2. Ayuda-Durán P, Hermansen JU, Giliberto M, Yin Y, Hanes R, Gordon S, Kuusanmäki H, Brodersen AM, Andersen AN, Taskén K, Wennerberg K, Enserink JM, Skånland SS (2023)
    Standardized assays to monitor drug sensitivity in hematologic cancers
    Cell Death Discov, 9 (1), 435
    DOI 10.1038/s41420-023-01722-5, PubMed 38040674
  3. García-Díaz N, Wei Q, Taskén K (2023)
    Small molecule inhibitors targeting regulatory T cells for cancer treatment
    Eur J Immunol, 54 (2), e2350448
    DOI 10.1002/eji.202350448, PubMed 37937687
  4. Hermansen JU, Yin Y, Urban A, Myklebust CV, Karlsen L, Melvold K, Tveita AA, Taskén K, Munthe LA, Tjønnfjord GE, Skånland SS (2023)
    A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine
    Cell Death Discov, 9 (1), 125
    DOI 10.1038/s41420-023-01426-w, PubMed 37055391
  5. Köhn-Luque A, Myklebust EM, Tadele DS, Giliberto M, Schmiester L, Noory J, Harivel E, Arsenteva P, Mumenthaler SM, Schjesvold F, Taskén K, Enserink JM, Leder K, Frigessi A, Foo J (2023)
    Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data
    Cell Rep Methods, 3 (3), 100417
    DOI 10.1016/j.crmeth.2023.100417, PubMed 37056380
  6. Le Tourneau C, André F, Helland Å, Mileshkin L, Minnaard W, Schiel A, Taskén K, Thomas DM, Veronese ML, Durán-Pacheco G, Leyens L, Rufibach K, Thomas M, Krämer A (2023)
    Modified study designs to expand treatment options in personalised oncology: a multistakeholder view
    Eur J Cancer, 194, 113278
    DOI 10.1016/j.ejca.2023.113278, PubMed 37820553
  7. Skogestad J, Albert I, Hougen K, Lothe GB, Lunde M, Eken OS, Veras I, Huynh NTT, Børstad M, Marshall S, Shen X, Louch WE, Robinson EL, Cleveland JC, Ambardekar AV, Schwisow JA, Jonas E, Calejo AI, Morth JP, Taskén K, Melleby AO, Lunde PK, Sjaastad I, Carlson CR, Aronsen JM (2023)
    Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure
    Circulation, 147 (16), 1221-1236
    DOI 10.1161/CIRCULATIONAHA.121.054168, PubMed 36876489
  8. Skånland SS, Brown JR (2023)
    PI3K inhibitors in chronic lymphocytic leukemia: where do we go from here?
    Haematologica, 108 (1), 9-21
    DOI 10.3324/haematol.2022.281266, PubMed 35899388
  9. Spasevska I, Sharma A, Steen CB, Josefsson SE, Blaker YN, Kolstad A, Rustad EH, Meyer S, Isaksen K, Chellappa S, Kushekhar K, Beiske K, Førsund MS, Spetalen S, Holte H, Østenstad B, Brodtkorb M, Kimby E, Olweus J, Taskén K, Newman AM, Lorenz S, Smeland EB, Alizadeh AA, Huse K et al. (2023)
    Diversity of intratumoral regulatory T cells in B-cell non-Hodgkin lymphoma
    Blood Adv, 7 (23), 7216-7230
    DOI 10.1182/bloodadvances.2023010158, PubMed 37695745
  10. Zhang D, Harris HM, Chen J, Judy J, James G, Kelly A, McIntosh J, Tenn-McClellan A, Ambing E, Tan YS, Lu H, Gajewski S, Clifton MC, Yung S, Robbins DW, Pirooznia M, Skånland SS, Gaglione E, Mhibik M, Underbayev C, Ahn IE, Sun C, Herman SEM, Noviski M, Wiestner A (2023)
    NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts
    Blood, 141 (13), 1584-1596
    DOI 10.1182/blood.2022016934, PubMed 36375120

Publications 2022

  1. Aronson JH, Skånland SS, Roeker LE, Thompson MC, Mato AR (2022)
    Approach to a patient with "double refractory" chronic lymphocytic leukemia: "Double, double toil and trouble" (Shakespeare)
    Am J Hematol, 97 Suppl 2, S19-S25
    DOI 10.1002/ajh.26682, PubMed 36125036
  2. Athanasiadis P, Ianevski A, Skånland SS, Aittokallio T (2022)
    Computational Pipeline for Rational Drug Combination Screening in Patient-Derived Cells
    Methods Mol Biol, 2449, 327-348
    DOI 10.1007/978-1-0716-2095-3_14, PubMed 35507270
  3. Flobak Å, Skånland SS, Hovig E, Taskén K, Russnes HG (2022)
    Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
    Trends Pharmacol Sci, 43 (11), 973-985
    DOI 10.1016/j.tips.2022.08.009, PubMed 36163057
  4. Giliberto M, Santana LM, Holien T, Misund K, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Coward E, Waage A, Taskén K, Skånland SS (2022)
    Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
    Front Oncol, 12, 1040730
    DOI 10.3389/fonc.2022.1040730, PubMed 36523963
  5. Giliberto M, Thimiri Govinda Raj DB, Cremaschi A, Skånland SS, Gade A, Tjønnfjord GE, Schjesvold F, Munthe LA, Taskén K (2022)
    Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically
    Mol Oncol, 16 (6), 1241-1258
    DOI 10.1002/1878-0261.13191, PubMed 35148457
  6. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 225
    DOI 10.1186/s12967-022-03432-5, PubMed 35568909
  7. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 317
    DOI 10.1186/s12967-022-03518-0, PubMed 35841045
  8. Imbery JF, Heinzelbecker J, Jebsen JK, McGowan M, Myklebust C, Bottini N, Stanford SM, Skånland SS, Tveita A, Tjønnfjord GE, Munthe LA, Szodoray P, Nakken B (2022)
    T-helper cell regulation of CD45 phosphatase activity by galectin-1 and CD43 governs chronic lymphocytic leukaemia proliferation
    Br J Haematol, 198 (3), 556-573
    DOI 10.1111/bjh.18285, PubMed 35655388
  9. Skånland SS, Inngjerdingen M, Bendiksen H, York J, Spetalen S, Munthe LA, Tjønnfjord GE (2022)
    Functional testing of relapsed chronic lymphocytic leukemia guides precision medicine and maps response and resistance mechanisms. An index case
    Haematologica, 107 (8), 1994-1998
    DOI 10.3324/haematol.2021.280393, PubMed 35236056
  10. Skånland SS, Tjønnfjord GE (2022)
    Determining drug dose in the era of targeted therapies: playing it (un)safe?
    Blood Cancer J, 12 (8), 123
    DOI 10.1038/s41408-022-00720-7, PubMed 35999205
  11. Taskén K, Russnes HEG, Aas E, Bjørge L, Blix ES, CONNECT Public–Private Partnership Consortium, Enerly E, Fagereng GL, Flobak Å, Gilje B, Gjertsen BT, Guren TK, Heix J, Hovig E, Hovland R, InPreD-Norway and National Molecular Tumor Board Consortium, IMPRESS-Norway Consortium, Lønning PE, Meza-Zepeda LA, Mæhle PM, Nilsen HL, Thoresen SØ, Widerberg K, Smeland S, Helland Å (2022)
    A national precision cancer medicine implementation initiative for Norway
    Nat Med, 28 (5), 885-887
    DOI 10.1038/s41591-022-01777-4, PubMed 35513529
  12. Wei Q, Taskén K (2022)
    Immunoregulatory signal networks and tumor immune evasion mechanisms: insights into therapeutic targets and agents in clinical development
    Biochem J, 479 (20), 2219-2260
    DOI 10.1042/BCJ20210233, PubMed 36305711
  13. Yin Y, Athanasiadis P, Karlsen L, Urban A, Xu H, Murali I, Fernandes SM, Arribas AJ, Hilli AK, Taskén K, Bertoni F, Mato AR, Normant E, Brown JR, Tjønnfjord GE, Aittokallio T, Skånland SS (2022)
    Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
    Clin Cancer Res, 28 (20), 4444-4455
    DOI 10.1158/1078-0432.CCR-22-1221, PubMed 35998013

Publications 2021

  1. Chellappa S, Kushekhar K, Hagness M, Horneland R, Taskén K, Aandahl EM (2021)
    The Presence of Activated T Cell Subsets prior to Transplantation Is Associated with Increased Rejection Risk in Pancreas Transplant Recipients
    J Immunol, 207 (10), 2501-2511
    DOI 10.4049/jimmunol.2001103, PubMed 34607938
  2. Jenum S, Tonby K, Rueegg CS, Rühwald M, Kristiansen MP, Bang P, Olsen IC, Sellæg K, Røstad K, Mustafa T, Taskén K, Kvale D, Mortensen R, Dyrhol-Riise AM (2021)
    A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
    Nat Commun, 12 (1), 6774
    DOI 10.1038/s41467-021-27029-6, PubMed 34811370
  3. Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
    A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
    Sci Transl Med, 13 (582)
    DOI 10.1126/scitranslmed.abb0036, PubMed 33627483
  4. Jøntvedt Jørgensen M, Nore KG, Aass HCD, Layre E, Nigou J, Mortensen R, Tasken K, Kvale D, Jenum S, Tonby K, Dyrhol-Riise AM (2021)
    Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients
    Front Cell Infect Microbiol, 11, 669623
    DOI 10.3389/fcimb.2021.669623, PubMed 34307194
  5. Lone AM, Giansanti P, Jørgensen MJ, Gjerga E, Dugourd A, Scholten A, Saez-Rodriguez J, Heck AJR, Taskén K (2021)
    Systems approach reveals distinct and shared signaling networks of the four PGE2 receptors in T cells
    Sci Signal, 14 (703), eabc8579
    DOI 10.1126/scisignal.abc8579, PubMed 34609894
  6. Lone AM, Taskén K (2021)
    Phosphoproteomics-Based Characterization of Prostaglandin E2 Signaling in T Cells
    Mol Pharmacol, 99 (5), 370-382
    DOI 10.1124/molpharm.120.000170, PubMed 33674363
  7. Lorvik KB, Meyer-Myklestad MH, Kushekar K, Handeland C, Medhus AW, Lund-Iversen M, Stiksrud B, Kvale D, Dyrhol-Riise AM, Taskén K, Reikvam DH (2021)
    Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4+ T Cells in HIV-Infected Immunological Non-Responders
    Front Immunol, 12, 744155
    DOI 10.3389/fimmu.2021.744155, PubMed 34691047
  8. Melvold K, Giliberto M, Karlsen L, Ayuda-Durán P, Hanes R, Holien T, Enserink J, Brown JR, Tjønnfjord GE, Taskén K, Skånland SS (2021)
    Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
    Mol Oncol, 16 (5), 1153-1170
    DOI 10.1002/1878-0261.13153, PubMed 34861096
  9. Roeker LE, Eyre TA, Thompson MC, Lamanna N, Coltoff AR, Davids MS, Baker PO, Leslie L, Rogers KA, Allan JN, Cordoba R, Lopez-Garcia A, Antic D, Pagel JM, Martinez-Calle N, García-Marco JA, Hernández-Rivas JÁ, Miras F, Coombs CC, Österborg A, Hansson L, Seddon AN, López Jiménez J, Wilson MR, El-Sharkawi D et al. (2021)
    COVID-19 in patients with CLL: improved survival outcomes and update on management strategies
    Blood, 138 (18), 1768-1773
    DOI 10.1182/blood.2021011841, PubMed 34297826
  10. Skånland SS, Mato AR (2021)
    Overcoming resistance to targeted therapies in chronic lymphocytic leukemia
    Blood Adv, 5 (1), 334-343
    DOI 10.1182/bloodadvances.2020003423, PubMed 33570649
  11. Yaqub S, Bjørnbeth BA, Angelsen JH, Fristrup CW, Grønbech JE, Hemmingsson O, Isaksson B, Juel IS, Larsen PN, Lindell G, Mortensen FV, Mortensen KE, Rizell M, Sandström P, Sandvik OM, Sparrelid E, Taflin H, Taskén K, ASAC study group (2021)
    Aspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial
    Trials, 22 (1), 642
    DOI 10.1186/s13063-021-05587-w, PubMed 34544470

Publications 2020

  1. Caglayan S, Hashim A, Cieslar-Pobuda A, Jensen V, Behringer S, Talug B, Chu DT, Pecquet C, Rogne M, Brech A, Brorson SH, Nagelhus EA, Hannibal L, Boschi A, Taskén K, Staerk J (2020)
    Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
    iScience, 23 (6), 101154
    DOI 10.1016/j.isci.2020.101154, PubMed 32450518
  2. Mato AR, Roeker LE, Lamanna N, Allan JN, Leslie L, Pagel JM, Patel K, Osterborg A, Wojenski D, Kamdar M, Huntington SF, Davids MS, Brown JR, Antic D, Jacobs R, Ahn IE, Pu J, Isaac KM, Barr PM, Ujjani CS, Geyer MB, Berman E, Zelenetz AD, Malakhov N, Furman RR et al. (2020)
    Outcomes of COVID-19 in patients with CLL: a multicenter international experience
    Blood, 136 (10), 1134-1143
    DOI 10.1182/blood.2020006965, PubMed 32688395
  3. Meås HZ, Haug M, Beckwith MS, Louet C, Ryan L, Hu Z, Landskron J, Nordbø SA, Taskén K, Yin H, Damås JK, Flo TH (2020)
    Sensing of HIV-1 by TLR8 activates human T cells and reverses latency
    Nat Commun, 11 (1), 147
    DOI 10.1038/s41467-019-13837-4, PubMed 31919342
  4. Skånland SS, Karlsen L, Taskén K (2020)
    B cell signalling pathways-New targets for precision medicine in chronic lymphocytic leukaemia
    Scand J Immunol, 92 (5), e12931
    DOI 10.1111/sji.12931, PubMed 32640099

Publications 2019

  1. Brennecke P, Rasina D, Aubi O, Herzog K, Landskron J, Cautain B, Vicente F, Quintana J, Mestres J, Stechmann B, Ellinger B, Brea J, Kolanowski JL, Pilarski R, Orzaez M, Pineda-Lucena A, Laraia L, Nami F, Zielenkiewicz P, Paruch K, Hansen E, von Kries JP, Neuenschwander M, Specker E, Bartunek P et al. (2019)
    EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
    SLAS Discov, 24 (3), 398-413
    DOI 10.1177/2472555218816276, PubMed 30616481
  2. Chellappa S, Kushekhar K, Munthe LA, Tjønnfjord GE, Aandahl EM, Okkenhaug K, Taskén K (2019)
    The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
    J Immunol, 202 (5), 1397-1405
    DOI 10.4049/jimmunol.1701703, PubMed 30692213
  3. Cremaschi A, Argiento R, Shoemaker K, Peterson C, Vannucci M (2019)
    Hierarchical Normalized Completely Random Measures for Robust Graphical Modeling
    Bayesian Anal, 14 (4), 1271-1301
    DOI 10.1214/19-ba1153, PubMed 32431780
  4. Dukic AR, Gerbaud P, Guibourdenche J, Thiede B, Taskén K, Pidoux G (2019)
    Correction: Ezrin-anchored PKA phosphorylates serine 369 and 373 on connexin 43 to enhance gap junction assembly, communication, and cell fusion
    Biochem J, 476 (13), 1927
    DOI 10.1042/BCJ-2017-0529_COR, PubMed 31266855
  5. Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ (2019)
    Remodeling of secretory lysosomes during education tunes functional potential in NK cells
    Nat Commun, 10 (1), 514
    DOI 10.1038/s41467-019-08384-x, PubMed 30705279
  6. Skånland SS, Cieślar-Pobuda A (2019)
    Off-label uses of drugs for depression
    Eur J Pharmacol, 865, 172732
    DOI 10.1016/j.ejphar.2019.172732, PubMed 31622593
  7. Skånland SS, Cremaschi A, Bendiksen H, Hermansen JU, Thimiri Govinda Raj DB, Munthe LA, Tjønnfjord GE, Taskén K (2019)
    An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL
    Leukemia, 34 (2), 478-487
    DOI 10.1038/s41375-019-0569-7, PubMed 31471562
  8. Skånland SS, Taskén K (2019)
    Carboxyl-Terminal Src Kinase Binds CD28 upon Activation and Mutes Downstream Signaling
    J Immunol, 203 (4), 1055-1063
    DOI 10.4049/jimmunol.1801660, PubMed 31292214
  9. Sukonina V, Ma H, Zhang W, Bartesaghi S, Subhash S, Heglind M, Foyn H, Betz MJ, Nilsson D, Lidell ME, Naumann J, Haufs-Brusberg S, Palmgren H, Mondal T, Beg M, Jedrychowski MP, Taskén K, Pfeifer A, Peng XR, Kanduri C, Enerbäck S (2019)
    FOXK1 and FOXK2 regulate aerobic glycolysis
    Nature, 566 (7743), 279-283
    DOI 10.1038/s41586-019-0900-5, PubMed 30700909

Publications 2018

  1. Hermansen JU, Tjønnfjord GE, Munthe LA, Taskén K, Skånland SS (2018)
    Cryopreservation of primary B cells minimally influences their signaling responses
    Sci Rep, 8 (1), 17651
    DOI 10.1038/s41598-018-36121-9, PubMed 30518828
  2. Rogne M, Chu DT, Küntziger TM, Mylonakou MN, Collas P, Tasken K (2018)
    OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells
    Mol Biol Cell, 29 (12), 1487-1501
    DOI 10.1091/mbc.E17-09-0538, PubMed 29688805
  3. Schwab C, Gabrysch A, Olbrich P, Patiño V, Warnatz K, Wolff D, Hoshino A, Kobayashi M, Imai K, Takagi M, Dybedal I, Haddock JA, Sansom DM, Lucena JM, Seidl M, Schmitt-Graeff A, Reiser V, Emmerich F, Frede N, Bulashevska A, Salzer U, Schubert D, Hayakawa S, Okada S, Kanariou M et al. (2018)
    Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects
    J Allergy Clin Immunol, 142 (6), 1932-1946
    DOI 10.1016/j.jaci.2018.02.055, PubMed 29729943

Publications 2010

  1. Esaki Y, Li Y, Sakata D, Yao C, Segi-Nishida E, Matsuoka T, Fukuda K, Narumiya S (2010)
    Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis
    Proc Natl Acad Sci U S A, 107 (27), 12233-8
    DOI 10.1073/pnas.0915112107, PubMed 20566843

Publications 2009

  1. Huang H, Qiao R, Zhao D, Zhang T, Li Y, Yi F, Lai F, Hong J, Ding X, Yang Z, Zhang L, Du Q, Liang Z (2009)
    Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs
    Nucleic Acids Res, 37 (22), 7560-9
    DOI 10.1093/nar/gkp835, PubMed 19815667
  2. Yao C, Sakata D, Esaki Y, Li Y, Matsuoka T, Kuroiwa K, Sugimoto Y, Narumiya S (2009)
    Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion
    Nat Med, 15 (6), 633-40
    DOI 10.1038/nm.1968, PubMed 19465928

 
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