Semiconductor nanoparticles, so-called quantum dots, are being used for fluorescent imaging of cancer cells in vitro and in animals in vivo. We introduce the concept of using these nanoparticles as photosensitizers. Real-time monitoring using Electric Cell-substrate Impedance Sensing (ECIS) of cancer cell responses to photodynamic toxicity caused by quantum dots are studied in this project.
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Espeland K, Kleinauskas A, Juzenas P, Darvekar S, Vasovic V, Warloe T, Christensen E, Jahnsen J, Peng Q(2023) Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells from Patients with Crohn's Disease Int J Mol Sci, 24(5) DOI 10.3390/ijms24054554, PubMed 36901982