Mucosal Immunology and Cancer Research

Publications 2024

Das S, Stamnaes J, Kemppainen E, Hervonen K, Lundin KEA, Parmar N, Jahnsen FL, Jahnsen J, Lindfors K, Salmi T, Iversen R, Sollid LM (2024)
Correction to: Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), 11 (21), e2400894
DOI 10.1002/advs.202400894, PubMed 38477397

Majid U, Bergsland CH, Sveen A, Bruun J, Eilertsen IA, Bækkevold ES, Nesbakken A, Yaqub S, Jahnsen FL, Lothe RA (2024)
The prognostic effect of tumor-associated macrophages in stage I-III colorectal cancer depends on T cell infiltration
Cell Oncol (Dordr), 47 (4), 1267-1276
DOI 10.1007/s13402-024-00926-w, PubMed 38407700

McDonald GB, Landsverk OJB, McGovern DPB, Aasebø A, Paulsen V, Haritunians T, Reims HM, McLaughlin BM, Zisman T, Li D, Elholm ETMM, Jahnsen FL, Georges GE, Gedde-Dahl T (2024)
Allogeneic bone marrow transplantation for patients with treatment-refractory Crohn's Disease
Heliyon, 10 (1), e24026
DOI 10.1016/j.heliyon.2024.e24026, PubMed 38283244

Oliver AJ, Huang N, Bartolome-Casado R, Li R, Koplev S, Nilsen HR, Moy M, Cakir B, Polanski K, Gudiño V, Melón-Ardanaz E, Sumanaweera D, Dimitrov D, Milchsack LM, FitzPatrick MEB, Provine NM, Boccacino JM, Dann E, Predeus AV, To K, Prete M, Chapman JA, Masi AC, Stephenson E, Engelbert J et al. (2024)
Single-cell integration reveals metaplasia in inflammatory gut diseases
Nature, 635 (8039), 699-707
DOI 10.1038/s41586-024-07571-1, PubMed 39567783

Polański K, Bartolomé-Casado R, Sarropoulos I, Xu C, England N, Jahnsen FL, Teichmann SA, Yayon N (2024)
Bin2cell reconstructs cells from high resolution Visium HD data
Bioinformatics, 40 (9)
DOI 10.1093/bioinformatics/btae546, PubMed 39250728

Publications 2023

Chauhan SK, Bartolomé Casado R, Landsverk OJB, Johannessen H, Phung D, Nilsen HR, Sætre F, Jahnsen J, Horneland R, Yaqub S, Aandahl EM, Lundin KEA, Bækkevold ES, Jahnsen FL (2023)
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
J Allergy Clin Immunol, 152 (1), 278-289.e6
DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861

Das S, Stamnaes J, Kemppainen E, Hervonen K, Lundin KEA, Parmar N, Jahnsen FL, Jahnsen J, Lindfors K, Salmi T, Iversen R, Sollid LM (2023)
Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), 10 (25), e2300401
DOI 10.1002/advs.202300401, PubMed 37424036

Zilbauer M, James KR, Kaur M, Pott S, Li Z, Burger A, Thiagarajah JR, Burclaff J, Jahnsen FL, Perrone F, Ross AD, Matteoli G, Stakenborg N, Sujino T, Moor A, Bartolome-Casado R, Bækkevold ES, Zhou R, Xie B, Lau KS, Din S, Magness ST, Yao Q, Beyaz S, Arends M et al. (2023)
A Roadmap for the Human Gut Cell Atlas
Nat Rev Gastroenterol Hepatol, 20 (9), 597-614
DOI 10.1038/s41575-023-00784-1, PubMed 37258747

Publications 2022

Atlasy N, Bujko A, Bækkevold ES, Brazda P, Janssen-Megens E, Lundin KEA, Jahnsen J, Jahnsen FL, Stunnenberg HG (2022)
Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease
Nat Commun, 13 (1), 4920
DOI 10.1038/s41467-022-32691-5, PubMed 35995787

Domanska D, Majid U, Karlsen VT, Merok MA, Beitnes AR, Yaqub S, Bækkevold ES, Jahnsen FL (2022)
Single-cell transcriptomic analysis of human colonic macrophages reveals niche-specific subsets
J Exp Med, 219 (3)
DOI 10.1084/jem.20211846, PubMed 35139155

Umu SU, Rapp Vander-Elst K, Karlsen VT, Chouliara M, Bækkevold ES, Jahnsen FL, Domanska D (2022)
Cellsnake: a user-friendly tool for single-cell RNA sequencing analysis
Gigascience, 12
DOI 10.1093/gigascience/giad091, PubMed 37889009

Aasebo AT, Gedde-Dahl T, Reims HM, Baekkevold ES, Jahnsen FL (2022)
Calprotectin Expressing Donor-Derived Macrophages Increase in Acute Gastrointestinal Graft-Versus-Host Disease
Transplant Cell Ther, 28 (5), 248.e1-248.e8
DOI 10.1016/j.jtct.2022.01.028, PubMed 35144036

Publications 2021

Bartolomé-Casado R, Bækkevold ES, Jahnsen FL (2021)
Response to Lauro and Zorzetti
Mucosal Immunol, 14 (6), 1395-1396
DOI 10.1038/s41385-021-00454-y, PubMed 34535772

Jahnsen FL, Johansen FE (2021)
Legends of allergology and immunology: Per Brandtzaeg - Pillar of mucosal immunology
Allergy, 76 (8), 2634-2635
DOI 10.1111/all.14824, PubMed 33752264

Sikkeland LIB, Qiao SW, Ueland T, Myrdal O, Wyrożemski Ł, Aukrust P, Jahnsen FL, Sjåheim T, Kongerud J, Molberg Ø, Lund MB, Bækkevold ES (2021)
Lung CD4+ T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-γ
Eur Respir J, 57 (3)
DOI 10.1183/13993003.00983-2020, PubMed 33154027

Publications 2020

Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Sætre F, Hagen KT, Yaqub S, Øyen O, Horneland R, Aandahl EM, Aabakken L, Bækkevold ES, Jahnsen FL (2020)
CD4⁺ T cells persist for years in the human small intestine and display a T_H1 cytokine profile
Mucosal Immunol, 14 (2), 402-410
DOI 10.1038/s41385-020-0315-5, PubMed 32572129

Divito SJ, Aasebø AT, Matos TR, Hsieh PC, Collin M, Elco CP, O'Malley JT, Bækkevold ES, Reims H, Gedde-Dahl T, Hagerstrom M, Hilaire J, Lian JW, Milford EL, Pinkus GS, Ho VT, Soiffer RJ, Kim HT, Mihm MC, Ritz J, Guleria I, Cutler CS, Clark RA, Jahnsen FL, Kupper TS (2020)
Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease
J Clin Invest, 130 (9), 4624-4636
DOI 10.1172/JCI129965, PubMed 32516138

Publications 2019

Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Richter L, Phung D, Greiff V, Risnes LF, Yao Y, Neumann RS, Yaqub S, Øyen O, Horneland R, Aandahl EM, Paulsen V, Sollid LM, Qiao SW, Baekkevold ES, Jahnsen FL (2019)
Resident memory CD8 T cells persist for years in human small intestine
J Exp Med, 216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737

Seiron P, Wiberg A, Kuric E, Krogvold L, Jahnsen FL, Dahl-Jørgensen K, Skog O, Korsgren O (2019)
Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced
J Pathol Clin Res, 5 (4), 248-255
DOI 10.1002/cjp2.140, PubMed 31493350

Publications 2018

Eguíluz-Gracia I, Malmstrom K, Dheyauldeen SA, Lohi J, Sajantila A, Aaløkken R, Sundaram AYM, Gilfillan GD, Makela M, Baekkevold ES, Jahnsen FL (2018)
Monocytes accumulate in the airways of children with fatal asthma
Clin Exp Allergy, 48 (12), 1631-1639
DOI 10.1111/cea.13265, PubMed 30184280

Høydahl LS, Richter L, Frick R, Snir O, Gunnarsen KS, Landsverk OJB, Iversen R, Jeliazkov JR, Gray JJ, Bergseng E, Foss S, Qiao SW, Lundin KEA, Jahnsen J, Jahnsen FL, Sandlie I, Sollid LM, Løset GÅ (2018)
Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease
Gastroenterology, 156 (5), 1428-1439.e10
DOI 10.1053/j.gastro.2018.12.013, PubMed 30593798

Richter L, Landsverk OJB, Atlasy N, Bujko A, Yaqub S, Horneland R, Øyen O, Aandahl EM, Lundin KEA, Stunnenberg HG, Bækkevold ES, Jahnsen FL (2018)
Transcriptional profiling reveals monocyte-related macrophages phenotypically resembling DC in human intestine
Mucosal Immunol, 11 (5), 1512-1523
DOI 10.1038/s41385-018-0060-1, PubMed 30038215

van Bergenhenegouwen J, Braber S, Loonstra R, Buurman N, Rutten L, Knipping K, Savelkoul PJ, Harthoorn LF, Jahnsen FL, Garssen J, Hartog A (2018)
Oral exposure to the free amino acid glycine inhibits the acute allergic response in a model of cow's milk allergy in mice
Nutr Res, 58, 95-105
DOI 10.1016/j.nutres.2018.07.005, PubMed 30340819

Publications 2017

Bujko A, Atlasy N, Landsverk OJB, Richter L, Yaqub S, Horneland R, Øyen O, Aandahl EM, Aabakken L, Stunnenberg HG, Bækkevold ES, Jahnsen FL (2017)
Transcriptional and functional profiling defines human small intestinal macrophage subsets
J Exp Med, 215 (2), 441-458
DOI 10.1084/jem.20170057, PubMed 29273642

Jahnsen FL, Bækkevold ES, Hov JR, Landsverk OJ (2017)
Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?
Trends Immunol, 39 (3), 196-208
DOI 10.1016/j.it.2017.10.006, PubMed 29162322

Landsverk OJ, Snir O, Casado RB, Richter L, Mold JE, Réu P, Horneland R, Paulsen V, Yaqub S, Aandahl EM, Øyen OM, Thorarensen HS, Salehpour M, Possnert G, Frisén J, Sollid LM, Baekkevold ES, Jahnsen FL (2017)
Antibody-secreting plasma cells persist for decades in human intestine
J Exp Med, 214 (2), 309-317
DOI 10.1084/jem.20161590, PubMed 28104812

Malmström K, Lohi J, Sajantila A, Jahnsen FL, Kajosaari M, Sarna S, Mäkelä MJ (2017)
Immunohistology and remodeling in fatal pediatric and adolescent asthma
Respir Res, 18 (1), 94
DOI 10.1186/s12931-017-0575-0, PubMed 28511697

Publications 2016

Ballke C, Gran E, Baekkevold ES, Jahnsen FL (2016)
Characterization of Regulatory T-Cell Markers in CD4+ T Cells of the Upper Airway Mucosa
PLoS One, 11 (2), e0148826
DOI 10.1371/journal.pone.0148826, PubMed 26866695

Eguíluz-Gracia I, Bosco A, Dollner R, Melum GR, Lexberg MH, Jones AC, Dheyauldeen SA, Holt PG, Bækkevold ES, Jahnsen FL (2016)
Rapid recruitment of CD14(+) monocytes in experimentally induced allergic rhinitis in human subjects
J Allergy Clin Immunol, 137 (6), 1872-1881.e12
DOI 10.1016/j.jaci.2015.11.025, PubMed 26851967

Eguíluz-Gracia I, Schultz HH, Sikkeland LI, Danilova E, Holm AM, Pronk CJ, Agace WW, Iversen M, Andersen C, Jahnsen FL, Baekkevold ES (2016)
Long-term persistence of human donor alveolar macrophages in lung transplant recipients
Thorax, 71 (11), 1006-1011
DOI 10.1136/thoraxjnl-2016-208292, PubMed 27329043

Jahnsen FL, Johansen FE, Haraldsen G (2016)
Obituary - In Memoriam Per Brandtzaeg
Scand J Immunol, 84 (6), 370-372
DOI 10.1111/sji.12505, PubMed 28025869

Schrøder M, Melum GR, Landsverk OJ, Bujko A, Yaqub S, Gran E, Aamodt H, Bækkevold ES, Jahnsen FL, Richter L (2016)
CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits
PLoS One, 11 (6), e0157387
DOI 10.1371/journal.pone.0157387, PubMed 27311059

Publications 2015

George R, Santhanam S, Samuel R, Chapla A, Hilmarsen HT, Braathen GJ, Reinholt FP, Jahnsen F, Khnykin D (2015)
Ichthyosis prematurity syndrome caused by a novel missense mutation in FATP4 gene-a case report from India
Clin Case Rep, 4 (1), 87-9
DOI 10.1002/ccr3.462, PubMed 26783444

Krogvold L, Wiberg A, Edwin B, Buanes T, Jahnsen FL, Hanssen KF, Larsson E, Korsgren O, Skog O, Dahl-Jørgensen K (2015)
Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes
Diabetologia, 59 (3), 492-501
DOI 10.1007/s00125-015-3820-4, PubMed 26602422

Skrindo I, Ballke C, Gran E, Johansen FE, Baekkevold ES, Jahnsen FL (2015)
IL-5 production by resident mucosal allergen-specific T cells in an explant model of allergic rhinitis
Clin Exp Allergy, 45 (8), 1296-304
DOI 10.1111/cea.12543, PubMed 25817862

Publications 2014

Bjerkan L, Schreurs O, Engen SA, Jahnsen FL, Baekkevold ES, Blix IJ, Schenck K (2014)
The short form of TSLP is constitutively translated in human keratinocytes and has characteristics of an antimicrobial peptide
Mucosal Immunol, 8 (1), 49-56
DOI 10.1038/mi.2014.41, PubMed 24850429

Danilova E, Skrindo I, Gran E, Hales BJ, Smith WA, Jahnsen J, Johansen FE, Jahnsen FL, Baekkevold ES (2014)
A role for CCL28-CCR3 in T-cell homing to the human upper airway mucosa
Mucosal Immunol, 8 (1), 107-14
DOI 10.1038/mi.2014.46, PubMed 24917456

Hammerstad SS, Jahnsen FL, Tauriainen S, Hyöty H, Paulsen T, Norheim I, Dahl-Jørgensen K (2014)
Immunological changes and increased expression of myxovirus resistance protein a in thyroid tissue of patients with recent onset and untreated Graves' disease
Thyroid, 24 (3), 537-44
DOI 10.1089/thy.2013.0287, PubMed 24032645

Jenum S, Grewal HM, Hokey DA, Kenneth J, Vaz M, Doherty TM, Jahnsen FL, TB Trials Study Group (2014)
The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy indian adolescents
PLoS One, 9 (7), e101224
DOI 10.1371/journal.pone.0101224, PubMed 24992314

Malmström K, Malmberg LP, O'Reilly R, Lindahl H, Kajosaari M, Saarinen KM, Saglani S, Jahnsen FL, Bush A, Haahtela T, Sarna S, Pelkonen AS, Mäkelä MJ (2014)
Lung function, airway remodeling, and inflammation in infants: outcome at 8 years
Ann Allergy Asthma Immunol, 114 (2), 90-6
DOI 10.1016/j.anai.2014.09.019, PubMed 25455519

Melum GR, Farkas L, Scheel C, Van Dieren B, Gran E, Liu YJ, Johansen FE, Jahnsen FL, Baekkevold ES (2014)
A thymic stromal lymphopoietin-responsive dendritic cell subset mediates allergic responses in the upper airway mucosa
J Allergy Clin Immunol, 134 (3), 613-621.e7
DOI 10.1016/j.jaci.2014.05.010, PubMed 24958565

Publications 2013

Brottveit M, Beitnes AC, Tollefsen S, Bratlie JE, Jahnsen FL, Johansen FE, Sollid LM, Lundin KE (2013)
Mucosal cytokine response after short-term gluten challenge in celiac disease and non-celiac gluten sensitivity
Am J Gastroenterol, 108 (5), 842-50
DOI 10.1038/ajg.2013.91, PubMed 23588237

Hammerstad SS, Jahnsen FL, Tauriainen S, Hyöty H, Paulsen T, Norheim I, Dahl-Jørgensen K (2013)
Inflammation and increased myxovirus resistance protein A expression in thyroid tissue in the early stages of Hashimoto's thyroiditis
Thyroid, 23 (3), 334-41
DOI 10.1089/thy.2012.0264, PubMed 22998463

Ráki M, Beitnes AC, Lundin KE, Jahnsen J, Jahnsen FL, Sollid LM (2013)
Plasmacytoid dendritic cells are scarcely represented in the human gut mucosa and are not recruited to the celiac lesion
Mucosal Immunol, 6 (5), 985-92
DOI 10.1038/mi.2012.136, PubMed 23340820

Publications 2012

Beitnes AC, Ráki M, Brottveit M, Lundin KE, Jahnsen FL, Sollid LM (2012)
Rapid accumulation of CD14+CD11c+ dendritic cells in gut mucosa of celiac disease after in vivo gluten challenge
PLoS One, 7 (3), e33556
DOI 10.1371/journal.pone.0033556, PubMed 22438948

Blaas HG, Salvesen KÅ, Khnykin D, Jahnsen FL, Eik-Nes SH (2012)
Prenatal sonographic assessment and perinatal course of ichthyosis prematurity syndrome
Ultrasound Obstet Gynecol, 39 (4), 473-7
DOI 10.1002/uog.9014, PubMed 21465607

Lin C, Hindes A, Burns CJ, Koppel AC, Kiss A, Yin Y, Ma L, Blumenberg M, Khnykin D, Jahnsen FL, Crosby SD, Ramanan N, Efimova T (2012)
Serum response factor controls transcriptional network regulating epidermal function and hair follicle morphogenesis
J Invest Dermatol, 133 (3), 608-617
DOI 10.1038/jid.2012.378, PubMed 23151848

Papadopoulos NG, Agache I, Bavbek S, Bilo BM, Braido F, Cardona V, Custovic A, Demonchy J, Demoly P, Eigenmann P, Gayraud J, Grattan C, Heffler E, Hellings PW, Jutel M, Knol E, Lötvall J, Muraro A, Poulsen LK, Roberts G, Schmid-Grendelmeier P, Skevaki C, Triggiani M, Vanree R, Werfel T et al. (2012)
Research needs in allergy: an EAACI position paper, in collaboration with EFA
Clin Transl Allergy, 2 (1), 21
DOI 10.1186/2045-7022-2-21, PubMed 23121771

Reikvam DH, Derrien M, Islam R, Erofeev A, Grcic V, Sandvik A, Gaustad P, Meza-Zepeda LA, Jahnsen FL, Smidt H, Johansen FE (2012)
Epithelial-microbial crosstalk in polymeric Ig receptor deficient mice
Eur J Immunol, 42 (11), 2959-70
DOI 10.1002/eji.201242543, PubMed 22865203

Publications 2011

Beitnes AC, Ráki M, Lundin KE, Jahnsen J, Sollid LM, Jahnsen FL (2011)
Density of CD163+ CD11c+ dendritic cells increases and CD103+ dendritic cells decreases in the coeliac lesion
Scand J Immunol, 74 (2), 186-94
DOI 10.1111/j.1365-3083.2011.02549.x, PubMed 21392045

Brottveit M, Ráki M, Bergseng E, Fallang LE, Simonsen B, Løvik A, Larsen S, Løberg EM, Jahnsen FL, Sollid LM, Lundin KE (2011)
Assessing possible celiac disease by an HLA-DQ2-gliadin Tetramer Test
Am J Gastroenterol, 106 (7), 1318-24
DOI 10.1038/ajg.2011.23, PubMed 21364548

Heier I, Søyland E, Krogstad AL, Rodríguez-Gallego C, Nenseter MS, Jahnsen FL (2011)
Sun exposure rapidly reduces plasmacytoid dendritic cells and inflammatory dermal dendritic cells in psoriatic skin
Br J Dermatol, 165 (4), 792-801
DOI 10.1111/j.1365-2133.2011.10430.x, PubMed 21623747

Inhoff O, Hausser I, Schneider SW, Khnykin D, Jahnsen FL, Sartoris J, Goerdt S, Peitsch WK (2011)
Ichthyosis prematurity syndrome caused by a novel fatty acid transport protein 4 gene mutation in a German infant
Arch Dermatol, 147 (6), 750-2
DOI 10.1001/archdermatol.2011.139, PubMed 21690550

Khnykin D, Miner JH, Jahnsen F (2011)
Role of fatty acid transporters in epidermis: Implications for health and disease
Dermatoendocrinol, 3 (2), 53-61
DOI 10.4161/derm.3.2.14816, PubMed 21695012

Khnykin D, Rønnevig J, Johnsson M, Sitek JC, Blaas HG, Hausser I, Johansen FE, Jahnsen FL (2011)
Ichthyosis prematurity syndrome: clinical evaluation of 17 families with a rare disorder of lipid metabolism
J Am Acad Dermatol, 66 (4), 606-16
DOI 10.1016/j.jaad.2011.04.014, PubMed 21856041

Reikvam DH, Erofeev A, Sandvik A, Grcic V, Jahnsen FL, Gaustad P, McCoy KD, Macpherson AJ, Meza-Zepeda LA, Johansen FE (2011)
Depletion of murine intestinal microbiota: effects on gut mucosa and epithelial gene expression
PLoS One, 6 (3), e17996
DOI 10.1371/journal.pone.0017996, PubMed 21445311

Skrindo I, Scheel C, Johansen FE, Jahnsen FL (2011)
Experimentally induced accumulation of Foxp3⁺ T cells in upper airway allergy
Clin Exp Allergy, 41 (7), 954-62
DOI 10.1111/j.1365-2222.2011.03710.x, PubMed 21418344

Søyland E, Heier I, Rodríguez-Gallego C, Mollnes TE, Johansen FE, Holven KB, Halvorsen B, Aukrust P, Jahnsen FL, de la Rosa Carrillo D, Krogstad AL, Nenseter MS (2011)
Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis
Br J Dermatol, 164 (2), 344-55
DOI 10.1111/j.1365-2133.2010.10149.x, PubMed 21271993

Publications 2010

Heier I, Malmström K, Sajantila A, Lohi J, Mäkelä M, Jahnsen FL (2010)
Characterisation of bronchus-associated lymphoid tissue and antigen-presenting cells in central airway mucosa of children
Thorax, 66 (2), 151-6
DOI 10.1136/thx.2010.149591, PubMed 21163807

Publications 2009

Holt PG, Strickland DH, Bosco A, Jahnsen FL (2009)
Pathogenic mechanisms of allergic inflammation: atopic asthma as a paradigm
Adv Immunol, 104, 51-113
DOI 10.1016/S0065-2776(08)04003-0, PubMed 20457116

Publications 2008

Heier I, Hofgaard PO, Brandtzaeg P, Jahnsen FL, Karlsson M (2008)
Depletion of CD4+ CD25+ regulatory T cells inhibits local tumour growth in a mouse model of B cell lymphoma
Clin Exp Immunol, 152 (2), 381-7
DOI 10.1111/j.1365-2249.2008.03642.x, PubMed 18341610

Heier I, Malmström K, Pelkonen AS, Malmberg LP, Kajosaari M, Turpeinen M, Lindahl H, Brandtzaeg P, Jahnsen FL, Mäkelä MJ (2008)
Bronchial response pattern of antigen presenting cells and regulatory T cells in children less than 2 years of age
Thorax, 63 (8), 703-9
DOI 10.1136/thx.2007.082974, PubMed 18250182

Holt PG, Strickland DH, Wikström ME, Jahnsen FL (2008)
Regulation of immunological homeostasis in the respiratory tract
Nat Rev Immunol, 8 (2), 142-52
DOI 10.1038/nri2236, PubMed 18204469

Skrindo I, Farkas L, Kvale EO, Johansen FE, Jahnsen FL (2008)
Depletion of CD4+CD25+CD127lo regulatory T cells does not increase allergen-driven T cell activation
Clin Exp Allergy, 38 (11), 1752-9
DOI 10.1111/j.1365-2222.2008.03081.x, PubMed 18681851

Publications 2007

Ráki M, Schjetne KW, Stamnaes J, Molberg Ø, Jahnsen FL, Issekutz TB, Bogen B, Sollid LM (2007)
Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells
Scand J Immunol, 65 (3), 213-20
DOI 10.1111/j.1365-3083.2006.01881.x, PubMed 17309775

Yaqub S, Henjum K, Mahic M, Jahnsen FL, Aandahl EM, Bjørnbeth BA, Taskén K (2007)
Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner
Cancer Immunol Immunother, 57 (6), 813-21
DOI 10.1007/s00262-007-0417-x, PubMed 17962941

Publications 2006

Farkas L, Kvale EO, Lund-Johansen F, Jahnsen FL (2006)
Plasmacytoid dendritic cells induce a distinct cytokine pattern in virus-specific CD4+ memory T cells that is modulated by CpG oligodeoxynucleotides
Scand J Immunol, 64 (4), 404-11
DOI 10.1111/j.1365-3083.2006.01792.x, PubMed 16970682

Hornell TM, Burster T, Jahnsen FL, Pashine A, Ochoa MT, Harding JJ, Macaubas C, Lee AW, Modlin RL, Mellins ED (2006)
Human dendritic cell expression of HLA-DO is subset specific and regulated by maturation
J Immunol, 176 (6), 3536-47
DOI 10.4049/jimmunol.176.6.3536, PubMed 16517722

Jahnsen FL, Strickland DH, Thomas JA, Tobagus IT, Napoli S, Zosky GR, Turner DJ, Sly PD, Stumbles PA, Holt PG (2006)
Accelerated antigen sampling and transport by airway mucosal dendritic cells following inhalation of a bacterial stimulus
J Immunol, 177 (9), 5861-7
DOI 10.4049/jimmunol.177.9.5861, PubMed 17056510

Kvale EO, Fløisand Y, Lund-Johansen F, Rollag H, Farkas L, Ghanekar S, Brandtzaeg P, Jahnsen FL, Olweus J (2006)
Plasmacytoid DCs regulate recall responses by rapid induction of IL-10 in memory T cells
Blood, 109 (8), 3369-76
DOI 10.1182/blood-2006-06-031484, PubMed 17158235

Ráki M, Tollefsen S, Molberg Ø, Lundin KE, Sollid LM, Jahnsen FL (2006)
A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells
Gastroenterology, 131 (2), 428-38
DOI 10.1053/j.gastro.2006.06.002, PubMed 16890596

Publications 2005

Dalgaard J, Beckstrøm KJ, Jahnsen FL, Brinchmann JE (2005)
Differential capability for phagocytosis of apoptotic and necrotic leukemia cells by human peripheral blood dendritic cell subsets
J Leukoc Biol, 77 (5), 689-98
DOI 10.1189/jlb.1204711, PubMed 15728242

Kvale EØ, Dalgaard J, Lund-Johansen F, Rollag H, Farkas L, Midtvedt K, Jahnsen FL, Brinchmann JE, Olweus J (2005)
CD11c+ dendritic cells and plasmacytoid DCs are activated by human cytomegalovirus and retain efficient T cell-stimulatory capability upon infection
Blood, 107 (5), 2022-9
DOI 10.1182/blood-2005-05-2016, PubMed 16269620

Rasmussen M, Skullerud K, Bakke SJ, Lebon P, Jahnsen FL (2005)
Cerebral thrombotic microangiopathy and antiphospholipid antibodies in Aicardi-Goutieres syndrome--report of two sisters
Neuropediatrics, 36 (1), 40-4
DOI 10.1055/s-2004-830532, PubMed 15776321

Publications 2004

Farkas L, Kvale EO, Johansen FE, Jahnsen FL, Lund-Johansen F (2004)
Plasmacytoid dendritic cells activate allergen-specific TH2 memory cells: modulation by CpG oligodeoxynucleotides
J Allergy Clin Immunol, 114 (2), 436-43
DOI 10.1016/j.jaci.2004.04.035, PubMed 15316529

Vuckovic S, Khalil D, Angel N, Jahnsen F, Hamilton I, Boyce A, Hock B, Hart DN (2004)
The CMRF58 antibody recognizes a subset of CD123hi dendritic cells in allergen-challenged mucosa
J Leukoc Biol, 77 (3), 344-51
DOI 10.1189/jlb.1004559, PubMed 15569693

Publications 2003

Andreassen AK, Jahnsen FL, Andersen R, Haga HJ (2003)
[Pulmonary veno-occlusive disease in a patient with scleroderma and the CREST syndrome]
Tidsskr Nor Laegeforen, 123 (23), 3391-2
PubMed 14713977

Baekkevold ES, Roussigné M, Yamanaka T, Johansen FE, Jahnsen FL, Amalric F, Brandtzaeg P, Erard M, Haraldsen G, Girard JP (2003)
Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules
Am J Pathol, 163 (1), 69-79
DOI 10.1016/S0002-9440(10)63631-0, PubMed 12819012

Chi JT, Chang HY, Haraldsen G, Jahnsen FL, Troyanskaya OG, Chang DS, Wang Z, Rockson SG, van de Rijn M, Botstein D, Brown PO (2003)
Endothelial cell diversity revealed by global expression profiling
Proc Natl Acad Sci U S A, 100 (19), 10623-8
DOI 10.1073/pnas.1434429100, PubMed 12963823

Huh JC, Strickland DH, Jahnsen FL, Turner DJ, Thomas JA, Napoli S, Tobagus I, Stumbles PA, Sly PD, Holt PG (2003)
Bidirectional interactions between antigen-bearing respiratory tract dendritic cells (DCs) and T cells precede the late phase reaction in experimental asthma: DC activation occurs in the airway mucosa but not in the lung parenchyma
J Exp Med, 198 (1), 19-30
DOI 10.1084/jem.20021328, PubMed 12835476

Jahnsen FL, Gran E, Haye R, Brandtzaeg P (2003)
Human nasal mucosa contains antigen-presenting cells of strikingly different functional phenotypes
Am J Respir Cell Mol Biol, 30 (1), 31-7
DOI 10.1165/rcmb.2002-0230OC, PubMed 12829449

Publications 2002

Jahnsen FL, Farkas L, Lund-Johansen F, Brandtzaeg P (2002)
Involvement of plasmacytoid dendritic cells in human diseases
Hum Immunol, 63 (12), 1201-5
DOI 10.1016/s0198-8859(02)00759-0, PubMed 12480264

Koss-Harnes D, Høyheim B, Anton-Lamprecht I, Gjesti A, Jørgensen RS, Jahnsen FL, Olaisen B, Wiche G, Gedde-Dahl T (2002)
A site-specific plectin mutation causes dominant epidermolysis bullosa simplex Ogna: two identical de novo mutations
J Invest Dermatol, 118 (1), 87-93
DOI 10.1046/j.0022-202x.2001.01591.x, PubMed 11851880

Publications 2001

Farkas L, Beiske K, Lund-Johansen F, Brandtzaeg P, Jahnsen FL (2001)
Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions
Am J Pathol, 159 (1), 237-43
DOI 10.1016/s0002-9440(10)61689-6, PubMed 11438470

Jahnsen FL, Moloney ED, Hogan T, Upham JW, Burke CM, Holt PG (2001)
Rapid dendritic cell recruitment to the bronchial mucosa of patients with atopic asthma in response to local allergen challenge
Thorax, 56 (11), 823-6
DOI 10.1136/thorax.56.11.823, PubMed 11641504

Publications 2000

Brandtzaeg P, Jahnsen FL (2000)
Immunohistochemistry in research and diagnosis of celiac disease
Methods Mol Med, 41, 203-39
DOI 10.1385/1-59259-082-9:203, PubMed 21374442

Jahnsen FL, Lund-Johansen F, Dunne JF, Farkas L, Haye R, Brandtzaeg P (2000)
Experimentally induced recruitment of plasmacytoid (CD123high) dendritic cells in human nasal allergy
J Immunol, 165 (7), 4062-8
DOI 10.4049/jimmunol.165.7.4062, PubMed 11034417

Publications 1999

Baekkevold ES, Jahnsen FL, Johansen FE, Bakke O, Gaudernack G, Brandtzaeg P, Haraldsen G (1999)
Culture characterization of differentiated high endothelial venule cells from human tonsils
Lab Invest, 79 (3), 327-36
PubMed 10092069

Brandtzaeg P, Baekkevold ES, Farstad IN, Jahnsen FL, Johansen FE, Nilsen EM, Yamanaka T (1999)
Regional specialization in the mucosal immune system: what happens in the microcompartments?
Immunol Today, 20 (3), 141-51
DOI 10.1016/s0167-5699(98)01413-3, PubMed 10203706

Jahnsen FL, Brandtzaeg P (1999)
Antigen presentation and stimulation of the immune system in human airways
Allergy, 54 Suppl 57, 37-49
DOI 10.1111/j.1398-9995.1999.tb04405.x, PubMed 10565479

Jahnsen FL, Haye R, Gran E, Brandtzaeg P, Johansen FE (1999)
Glucocorticosteroids inhibit mRNA expression for eotaxin, eotaxin-2, and monocyte-chemotactic protein-4 in human airway inflammation with eosinophilia
J Immunol, 163 (3), 1545-51
PubMed 10415058

Publications 1998

Brandtzaeg P, Farstad IN, Haraldsen G, Jahnsen FL (1998)
Cellular and molecular mechanisms for induction of mucosal immunity
Dev Biol Stand, 92, 93-108
PubMed 9554262

Jahnsen FL, Farstad IN, Aanesen JP, Brandtzaeg P (1998)
Phenotypic distribution of T cells in human nasal mucosa differs from that in the gut
Am J Respir Cell Mol Biol, 18 (3), 392-401
DOI 10.1165/ajrcmb.18.3.2995, PubMed 9490657

Nilsen EM, Jahnsen FL, Lundin KE, Johansen FE, Fausa O, Sollid LM, Jahnsen J, Scott H, Brandtzaeg P (1998)
Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease
Gastroenterology, 115 (3), 551-63
DOI 10.1016/s0016-5085(98)70134-9, PubMed 9721152

Nilsen EM, Johansen FE, Jahnsen FL, Lundin KE, Scholz T, Brandtzaeg P, Haraldsen G (1998)
Cytokine profiles of cultured microvascular endothelial cells from the human intestine
Gut, 42 (5), 635-42
DOI 10.1136/gut.42.5.635, PubMed 9659156

Utgaard JO, Jahnsen FL, Bakka A, Brandtzaeg P, Haraldsen G (1998)
Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells
J Exp Med, 188 (9), 1751-6
DOI 10.1084/jem.188.9.1751, PubMed 9802986

Publications 1997

Brandtzaeg P, Berstad AE, Farstad IN, Haraldsen G, Helgeland L, Jahnsen FL, Johansen FE, Natvig IB, Nilsen EM, Rugtveit J (1997)
Mucosal immunity--a major adaptive defence mechanism
Behring Inst Mitt (98), 1-23
PubMed 9382729

Brandtzaeg P, Jahnsen FL, Farstad IN, Haraldsen G (1997)
Mucosal immunology of the upper airways: an overview
Ann N Y Acad Sci, 830, 1-18
DOI 10.1111/j.1749-6632.1997.tb51875.x, PubMed 9616663

Jahnsen FL, Brandtzaeg P (1997)
Eosinophils and T cells in fatal asthma
Am J Respir Crit Care Med, 155 (3), 1167-8
DOI 10.1164/ajrccm.155.3.9117005, PubMed 9117005

Jahnsen FL, Brandtzaeg P, Haye R, Haraldsen G (1997)
Expression of functional VCAM-1 by cultured nasal polyp-derived microvascular endothelium
Am J Pathol, 150 (6), 2113-23
PubMed 9176402

Koss-Harnes D, Jahnsen FL, Wiche G, Søyland E, Brandtzaeg P, Gedde-Dahl T (1997)
Plectin abnormality in epidermolysis bullosa simplex Ogna: non-responsiveness of basal keratinocytes to some anti-rat plectin antibodies
Exp Dermatol, 6 (1), 41-8
DOI 10.1111/j.1600-0625.1997.tb00144.x, PubMed 9067706

Publications 1996

Brandtzaeg P, Jahnsen FL, Farstad IN (1996)
Immune functions and immunopathology of the mucosa of the upper respiratory pathways
Acta Otolaryngol, 116 (2), 149-59
DOI 10.3109/00016489609137812, PubMed 8725503

Publications 1995

Jahnsen F, Halstensen TS, Brandtzaeg P (1995)
Immunostaining with monoclonal antibodies to eosinophil cationic protein (EG1 and EG2) does not distinguish between resting and activated eosinophils in formalin-fixed tissue specimens
Adv Exp Med Biol, 371A, 283-6
DOI 10.1007/978-1-4615-1941-6_59, PubMed 8525926

Jahnsen FL, Brandtzaeg P (1995)
Monoclonal antibody EG2 reactivity cannot be used as an immunohistochemical activation marker for eosinophils
J Leukoc Biol, 57 (3), 513-4
DOI 10.1002/jlb.57.3.513, PubMed 7884325

Jahnsen FL, Haraldsen G, Aanesen JP, Haye R, Brandtzaeg P (1995)
Eosinophil infiltration is related to increased expression of vascular cell adhesion molecule-1 in nasal polyps
Am J Respir Cell Mol Biol, 12 (6), 624-32
DOI 10.1165/ajrcmb.12.6.7539273, PubMed 7539273

Publications 1994

Jahnsen FL, Brandtzaeg P, Halstensen TS (1994)
Monoclonal antibody EG2 does not provide reliable immunohistochemical discrimination between resting and activated eosinophils
J Immunol Methods, 175 (1), 23-36
DOI 10.1016/0022-1759(94)90328-x, PubMed 7930638

Jahnsen FL, Halstensen TS, Brandtzaeg P (1994)
Erroneous immunohistochemical application of monoclonal antibody EG2 to detect cellular activation
Lancet, 344 (8935), 1514-5
DOI 10.1016/s0140-6736(94)90336-0, PubMed 7968154

Jahnsen FL, Haraldsen G, Rugtveit J, Halstensen TS, Brandtzaeg P (1994)
Differential interference contrast microscopy combined with immunofluorescence: a new method to phenotype eosinophils in situ
J Immunol Methods, 173 (1), 77-91
DOI 10.1016/0022-1759(94)90285-2, PubMed 8034989

Publications 1993

Bjerke K, Halstensen TS, Jahnsen F, Pulford K, Brandtzaeg P (1993)
Distribution of macrophages and granulocytes expressing L1 protein (calprotectin) in human Peyer's patches compared with normal ileal lamina propria and mesenteric lymph nodes
Gut, 34 (10), 1357-63
DOI 10.1136/gut.34.10.1357, PubMed 8244101