Henrik S. Huitfeldt
- Group leader, professor
- +47 23 07 27 42
Publications 2021
[Environmental toxins in Norwegian food]
Tidsskr Nor Laegeforen, 141 (11)
DOI 10.4045/tidsskr.21.0499, PubMed 34423935
Environmental toxins in Norwegian food
Tidsskr. Nor. Laegeforen., 141 (11), 1038-1039
Publications 2020
Growth of hepatocellular carcinoma in the regenerating liver (vol 17, pg 866, 2011)
Liver Transplant., 26 (3), 469
DOI 10.1002/lt.25706
Publications 2018
Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene
Biochem Pharmacol, 158, 1-12
DOI 10.1016/j.bcp.2018.09.023, PubMed 30248327
Nondysplastic Ulcerative Colitis Has High Levels of the Homologous Recombination Repair Protein NUCKS1 and Low Levels of the DNA Damage Marker Gamma-H2AX
Inflamm Bowel Dis, 24 (3), 593-600
DOI 10.1093/ibd/izx071, PubMed 29462394
Publications 2017
Are environmental pollutants in the Norwegian diet harmful to children?
Tidsskr Nor Laegeforen, 137 (4), 295-297
DOI 10.4045/tidsskr.16.0978, PubMed 28225239
[Not Available]
Tidsskr Nor Laegeforen, 137 (14-15)
DOI 10.4045/tidsskr.17.0521, PubMed 28828793
Environmental toxins in the diet is about more than the fish
Tidsskr. Nor. Laegeforen., 137 (14-15), 973-974
Publications 2013
FAK regulates Cdk2 in EGF-stimulated primary cultures of hepatocytes
J Cell Physiol, 228 (6), 1304-13
DOI 10.1002/jcp.24287, PubMed 23168795
EGF activates autocrine TGFα to induce prolonged egf receptor signaling and hepatocyte proliferation
Cell Physiol Biochem, 32 (3), 511-22
DOI 10.1159/000354454, PubMed 24008581
The effect of hepatic progenitor cells on experimental hepatocellular carcinoma in the regenerating liver
Scand J Gastroenterol, 49 (1), 99-108
DOI 10.3109/00365521.2013.854406, PubMed 24188385
Publications 2012
RAF-targeted therapy for hepatocellular carcinoma in the regenerating liver
J Surg Oncol, 107 (4), 393-401
DOI 10.1002/jso.23224, PubMed 22927239
Deletion of the γ-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents
J Biol Chem, 287 (42), 35733-35746
DOI 10.1074/jbc.M112.368175, PubMed 22896705
Publications 2011
EGF-induced ERK-activation downstream of FAK requires rac1-NADPH oxidase
J Cell Physiol, 226 (9), 2267-78
DOI 10.1002/jcp.22563, PubMed 21660950
Growth of hepatocellular carcinoma in the regenerating liver
Liver Transpl, 17 (7), 866-74
DOI 10.1002/lt.22325, PubMed 21542129
Publications 2008
Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit
BMC Cell Biol, 9, 16
DOI 10.1186/1471-2121-9-16, PubMed 18380891
Distinct functions of H-Ras and K-Ras in proliferation and survival of primary hepatocytes due to selective activation of ERK and PI3K
J Cell Physiol, 215 (3), 818-26
DOI 10.1002/jcp.21367, PubMed 18163378
Publications 2007
Identification and characterization of two putative nuclear localization signals (NLS) in the DNA-binding protein NUCKS
Biochim Biophys Acta, 1773 (9), 1398-406
DOI 10.1016/j.bbamcr.2007.05.013, PubMed 17604136
MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments
FASEB J, 22 (2), 466-76
DOI 10.1096/fj.07-8650com, PubMed 17928366
CDK2 regulation through PI3K and CDK4 is necessary for cell cycle progression of primary rat hepatocytes
Cell Prolif, 40 (4), 475-87
DOI 10.1111/j.1365-2184.2007.00451.x, PubMed 17635516
Activation of the p53-p21(Cip1) pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes
Oncogene, 27 (19), 2763-71
DOI 10.1038/sj.onc.1210937, PubMed 18026139
Publications 2006
Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7
BMC Immunol, 7, 15
DOI 10.1186/1471-2172-7-15, PubMed 16839418
Regulation of rat alveolar type 2 cell proliferation in vitro involves type II cAMP-dependent protein kinase
Am J Physiol Lung Cell Mol Physiol, 292 (1), L232-9
DOI 10.1152/ajplung.00049.2006, PubMed 16980378
Publications 2005
Subtype-specific sorting of the ETA endothelin receptor by a novel endocytic recycling signal for G protein-coupled receptors
Mol Pharmacol, 67 (5), 1581-90
DOI 10.1124/mol.104.007013, PubMed 15713850
Cytoplasmic retention of peroxide-activated ERK provides survival in primary cultures of rat hepatocytes
Hepatology, 42 (1), 200-7
DOI 10.1002/hep.20762, PubMed 15962331
Altered regulation of EGF receptor signaling following a partial hepatectomy
J Cell Physiol, 202 (3), 707-16
DOI 10.1002/jcp.20171, PubMed 15389569
Publications 2004
Identification of 14-3-3zeta as an EGF receptor interacting protein
FEBS Lett, 569 (1-3), 207-10
DOI 10.1016/j.febslet.2004.05.068, PubMed 15225635
UV-radiation-induced internalization of the epidermal growth factor receptor requires distinct serine and tyrosine residues in the cytoplasmic carboxy-terminal domain
Radiat Res, 161 (6), 685-91
DOI 10.1667/rr3185, PubMed 15161351
Publications 2003
Labour market behaviour in a transition economy: the Czech experience
In Economic studies, The Department, Uppsala, 70, X, 110 s.
BIBSYS 030721342, ISBN 91-87268-77-9
Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor
Oncogene, 22 (52), 8509-18
DOI 10.1038/sj.onc.1207117, PubMed 14627991
High molecular weight DNA fragments are processed by caspase sensitive or caspase independent pathways in cultures of cerebellar granule neurons
Brain Res, 984 (1-2), 111-21
DOI 10.1016/s0006-8993(03)03119-6, PubMed 12932845
Publications 2002
CD38 is a marker of human lacteals
Virchows Arch, 441 (6), 605-13
DOI 10.1007/s00428-002-0679-9, PubMed 12461619
A putative DNA-binding domain in the NUCKS protein
Arch Biochem Biophys, 407 (2), 168-75
DOI 10.1016/s0003-9861(02)00513-1, PubMed 12413487
Localizing the EGF receptor
Nat Cell Biol, 4 (2), E22; author reply E22-3
DOI 10.1038/ncb0202-e22a, PubMed 11835048
UV induces tyrosine kinase-independent internalisation and endosome arrest of the EGF receptor
J Cell Sci, 115 (Pt 4), 793-803
DOI 10.1242/jcs.115.4.793, PubMed 11865035
Fluorescent histochemical techniques for analysis of intracellular signaling
J Histochem Cytochem, 50 (3), 289-303
DOI 10.1177/002215540205000301, PubMed 11850432
Publications 2001
Unemployment, labour market programmes and wage determination: evidence from the Czech and Slovak republics
In Working paper, The Department., Uppsala, 2001:1, 32 s.
BIBSYS 010317287
Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF
Eur J Cell Biol, 80 (4), 285-94
DOI 10.1078/0171-9335-00160, PubMed 11370743
Publications 2000
The carcinogen 2-acetylaminofluorene inhibits activation and nuclear accumulation of cyclin-dependent kinase 2 in growth-induced rat liver
Mol Carcinog, 27 (3), 190-9
DOI 10.1002/(SICI)1098-2744(200003)27:3<190::AID-MC6>3.3.CO;2-E, PubMed 10708481
Cell-specific expression of CCAAT/enhancer-binding protein delta (C/EBP delta) in epithelial lung cells
Exp Lung Res, 26 (5), 383-99
DOI 10.1080/019021400408326, PubMed 10914335
Immunocytochemical localization of Shc and activated EGF receptor in early endosomes after EGF stimulation of HeLa cells
J Histochem Cytochem, 48 (1), 21-33
DOI 10.1177/002215540004800103, PubMed 10653583
Impaired nuclear accumulation and shortened phosphorylation of ERK after growth factor stimulation in cultured hepatocytes from rats exposed to 2-acetylaminofluorene
Mol Carcinog, 28 (2), 84-96
DOI 10.1002/1098-2744(200006)28:2<84::aid-mc4>3.0.co;2-x, PubMed 10900465
Publications 1999
[Why is dioxin harmful?]
Tidsskr Nor Laegeforen, 119 (29), 4323-8
PubMed 10667131
Alteration of G1 cell-cycle protein expression and induction of p53 but not p21/waf1 by the DNA-modifying carcinogen 2-acetylaminofluorene in growth-stimulated hepatocytes in vitro
Mol Carcinog, 24 (1), 36-46
DOI 10.1002/(sici)1098-2744(199901)24:1<36::aid-mc6>3.0.co;2-i, PubMed 10029409
Publications 1998
Unemployment and labour market transitions in the Czech Republic: evidence from microdata
In Working paper, The Department., Uppsala, 1998:5, 36 s.
BIBSYS 980791146
Stress protein expression in rat liver during tumour promotion: induction of heat-shock protein 27 in hepatocytes exposed to 2-acetylaminofluorene
Carcinogenesis, 19 (9), 1559-63
DOI 10.1093/carcin/19.9.1559, PubMed 9771925
Endocytosed epidermal growth factor (EGF) receptors contribute to the EGF-mediated growth arrest in A431 cells by inducing a sustained increase in p21/CIP1
Exp Cell Res, 243 (1), 161-72
DOI 10.1006/excr.1998.4127, PubMed 9716460
Localization of cAMP-dependent signal transducers in early rat liver carcinogenesis
Histochem Cell Biol, 109 (3), 203-9
DOI 10.1007/s004180050219, PubMed 9541468
Does the mycotoxin citrinin function as a sun protectant in conidia from Penicillium verrucosum
Mycopathologia, 142 (1), 43-7
DOI 10.1023/A:1006934306071, PubMed 16284858
Publications 1997
UVB-induced formation of (6-4) photoproducts in the rat corneal epithelium
Acta Ophthalmol Scand, 75 (2), 120-3
DOI 10.1111/j.1600-0420.1997.tb00104.x, PubMed 9197553
Differential distribution and increased levels of ras proteins during lung development
Exp Lung Res, 23 (1), 35-49
DOI 10.3109/01902149709046046, PubMed 9028798
Publications 1996
Growth of colorectal polyps: redetection and evaluation of unresected polyps for a period of three years
Gut, 39 (3), 449-56
DOI 10.1136/gut.39.3.449, PubMed 8949653
Differential distribution of Met and epidermal growth factor receptor in normal and carcinogen-treated rat liver
J Histochem Cytochem, 44 (3), 227-33
DOI 10.1177/44.3.8648082, PubMed 8648082
Cyclic AMP-dependent protein kinase (cAK) in human B cells: co-localization of type I cAK (RI alpha 2 C2) with the antigen receptor during anti-immunoglobulin-induced B cell activation
Eur J Immunol, 26 (6), 1290-6
DOI 10.1002/eji.1830260617, PubMed 8647207
Expression of CYP2B1 in freshly isolated and proliferating cultures of epithelial rat lung cells
Exp Lung Res, 22 (6), 627-49
DOI 10.3109/01902149609070034, PubMed 8979047
Publications 1995
Topical application of 12-O-tetradecanoylphorbol-13-acetate induces dyssynchronous expression of keratins K1 and K10 in mouse epidermis
Cytometry, 19 (4), 313-9
DOI 10.1002/cyto.990190405, PubMed 7540972
Early cellular alterations in chemical liver carcinogenesis as addressed by immunohistochemical and molecular biological techniques
Arch Toxicol Suppl, 17, 547-53
DOI 10.1007/978-3-642-79451-3_48, PubMed 7786191
Topical application of calcitriol alters expression of filaggrin but not keratin K1 in mouse epidermis
Arch Dermatol Res, 287 (5), 480-7
DOI 10.1007/BF00373432, PubMed 7542861
CCAAT/enhancer-binding protein (C/EBP) immunoreactivity during rat liver carcinogenesis
Histochem Cell Biol, 104 (4), 287-94
DOI 10.1007/BF01464324, PubMed 8548562
Publications 1994
Expression of keratins K6 and K16 in regenerating mouse epidermis is less restricted by cell replication than the expression of K1 and K10
Epithelial Cell Biol, 3 (3), 96-101
PubMed 7534576
Application of cantharidin or 12-O-tetradecanoylphorbol-13-acetate on mouse epidermis induces a cell population shift that causes altered keratin distribution
Differentiation, 57 (3), 187-93
DOI 10.1046/j.1432-0436.1994.5730187.x, PubMed 7527355
In situ measurement of colorectal polyps to compare video and fiberoptic endoscopes
Endoscopy, 26 (5), 461-5
DOI 10.1055/s-2007-1009004, PubMed 7956955
Immunohistochemical and microfluorometric determination of hepatic DNA adduct removal in rats fed 2-acetylaminofluorene
Carcinogenesis, 15 (11), 2599-603
DOI 10.1093/carcin/15.11.2599, PubMed 7955112
Gene activation studied by immunological methods
Environ Health Perspect, 102 Suppl 6 (Suppl 6), 205-7
DOI 10.1289/ehp.94102s6205, PubMed 7889849
Pharmacokinetics and cytotoxicity of epirubicin (epi) in drug-resistant human hepatoma-cells (hb8065)
Int J Oncol, 4 (6), 1229-35
DOI 10.3892/ijo.4.6.1229, PubMed 21567042
Differential effects of topical retinoic acid application on keratin K1 and filaggrin expression in mouse epidermis
Differentiation, 57 (3), 179-85
DOI 10.1046/j.1432-0436.1994.5730179.x, PubMed 7527354
Ploidy-dependent growth and binucleation in cultured rat hepatocytes
Exp Cell Res, 214 (2), 551-60
DOI 10.1006/excr.1994.1293, PubMed 7925649
Location of cAMP-dependent protein kinase type I with the TCR-CD3 complex
Science, 263 (5143), 84-7
DOI 10.1126/science.8272870, PubMed 8272870
Publications 1993
Binucleation and polyploidization patterns in developmental and regenerative rat liver growth
Cell Prolif, 26 (6), 557-65
DOI 10.1111/j.1365-2184.1993.tb00033.x, PubMed 9116122
Microtubule-associated distribution of specific granules and secretion of atrial natriuretic factor in primary cultures of rat cardiomyocytes
Cell Tissue Res, 272 (2), 201-10
DOI 10.1007/BF00302725, PubMed 8513476
Publications 1992
Epithelial expression of HLA, secretory component (poly-Ig receptor), and adhesion molecules in the human alimentary tract
Ann N Y Acad Sci, 664, 157-79
DOI 10.1111/j.1749-6632.1992.tb39758.x, PubMed 1456647
BrdUrd incorporation studies for evaluation of spermatogenesis in the blue fox
Cytometry, 13 (4), 374-80
DOI 10.1002/cyto.990130407, PubMed 1526196
Species differences in carcinogen metabolism and interspecies extrapolation
IARC Sci Publ (116), 501-22
PubMed 1428094
Analytical methods for the study of liver cell proliferation
Cytometry, 13 (4), 404-15
DOI 10.1002/cyto.990130411, PubMed 1382009
Cytokeratins as epithelial differentiation markers in premalignant and malignant oral lesions
J Oral Pathol Med, 21 (1), 7-11
DOI 10.1111/j.1600-0714.1992.tb00960.x, PubMed 1375644
Ultrastructural morphometric analysis of human blood platelets exposed to minimal handling procedures
APMIS, 100 (10), 922-9
DOI 10.1111/j.1699-0463.1992.tb04020.x, PubMed 1445698
Publications 1991
Induction of in vitro resistance to 4'-epidoxorubicin and cis-dichlorodiammineplatinum in hepatoma cells
Anticancer Res, 11 (2), 817-23
PubMed 1676581
Carcinogen-induced alterations in rat liver DNA adduct formation determined by computerized fluorescent image analysis
Lab Invest, 64 (2), 207-14
PubMed 1997733
Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors
Carcinogenesis, 12 (11), 2063-7
DOI 10.1093/carcin/12.11.2063, PubMed 1718620
Quantitation and immunohistochemical localization of DNA adducts in rat embryos and associated yolk sac membranes exposed in vitro to N-acetoxy-2-acetylaminofluorene (N-Ac-AAF)
Teratog Carcinog Mutagen, 11 (2), 93-102
DOI 10.1002/tcm.1770110205, PubMed 1686678
Publications 1990
The spermatogenic cycle in the blue fox (Alopex lagopus): relative frequency and absolute duration of the different stages
Int J Androl, 13 (4), 315-26
DOI 10.1111/j.1365-2605.1990.tb01037.x, PubMed 2387650
In situ studies of aminofluorene-DNA adducts in experimental carcinogenesis
H. S. Huitfeldt, [Oslo], 1 b. (flere pag.)
BIBSYS 90071025x, ISBN 82-90252-29-3
Reduced DNA adduct formation in replicating liver cells during continuous feeding of a chemical carcinogen
Proc Natl Acad Sci U S A, 87 (15), 5955-8
DOI 10.1073/pnas.87.15.5955, PubMed 2198576
Chromosome site-specific immunohistochemical detection of DNA adducts in N-acetoxy-2-acetylaminofluorene--exposed Chinese hamster ovary cells
Mol Carcinog, 3 (1), 37-43
DOI 10.1002/mc.2940030109, PubMed 2322388
Two-colour immunofluorescence marker study of pleomorphic adenomas
Histochemistry, 93 (5), 459-68
DOI 10.1007/BF00266401, PubMed 2158957
Relation between T cell number and epithelial HLA class II expression quantified by image analysis in normal and inflamed human gastric mucosa
Gut, 31 (6), 647-52
DOI 10.1136/gut.31.6.647, PubMed 2199346
Publications 1989
UVB-induced (6-4) photoproducts in hairless mouse epidermis studied by quantitative immunohistochemistry
Carcinogenesis, 10 (9), 1669-73
DOI 10.1093/carcin/10.9.1669, PubMed 2670303
Publications 1988
Lack of acetylaminofluorene--DNA adduct formation in enzyme-altered foci of rat liver
Carcinogenesis, 9 (4), 647-52
DOI 10.1093/carcin/9.4.647, PubMed 2895693
Publications 1987
DNA adduct formation and removal during chronic administration of a carcinogenic aromatic amine
Prog Exp Tumor Res, 31, 33-41
DOI 10.1159/000413901, PubMed 3562858
Microfluorometric determination of DNA adducts in immunofluorescent-stained liver tissue from rats fed 2-acetylaminofluorene
Cancer Res, 47 (8), 2098-102
PubMed 2435406
Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins
Differentiation, 35 (2), 143-50
DOI 10.1111/j.1432-0436.1987.tb00162.x, PubMed 2450799
The distribution of HLA-DR determinants, secretory component (SC), amylase, lysozyme, IgA, IgM and IgD in fetal and postnatal salivary glands
Adv Exp Med Biol, 216B, 1431-8
PubMed 2447762
Pleomorphic adenomas contain a keratin-negative population of HLA-DR-positive dendritic cells
Adv Exp Med Biol, 216A, 437-44
DOI 10.1007/978-1-4684-5344-7_51, PubMed 2446470
Publications 1986
Re: Demonstration of lymphocyte surface antigens in paraffin-embedded human tissues
J Immunol Methods, 87 (2), 289-90
DOI 10.1016/0022-1759(86)90544-2, PubMed 3512728
Skin calcium-binding protein is a parvalbumin of the panniculus carnosus
J Invest Dermatol, 86 (2), 157-62
DOI 10.1111/1523-1747.ep12284197, PubMed 3745943
Immunohistochemical localization of DNA adducts in rat liver tissue and phenotypically altered foci during oral administration of 2-acetylaminofluorene
Carcinogenesis, 7 (1), 123-9
DOI 10.1093/carcin/7.1.123, PubMed 3510747
Publications 1985
Various keratin antibodies produce immunohistochemical staining of human myocardium and myometrium
Histochemistry, 83 (5), 381-9
DOI 10.1007/BF00509196, PubMed 2416716
Publications 1984
Human heart muscle contains keratin-like material in intercalated discs
Acta Pathol Microbiol Immunol Scand A, 92 (6), 481-2
DOI 10.1111/j.1699-0463.1984.tb04431.x, PubMed 6083696