Denis Khnykin

  • Senior scientist; PhD
  • +47 23 07 35 39

Publications 2020

Pietka W, Sundnes O, Hammarström C, Zucknick M, Khnykin D, Haraldsen G (2020)
Lack of interleukin-33 and its receptor does not prevent calcipotriol-induced atopic dermatitis-like inflammation in mice
Sci Rep, 10 (1), 6451
DOI 10.1038/s41598-020-63410-z, PubMed 32296080

Publications 2018

Crumrine D, Khnykin D, Krieg P, Man MQ, Celli A, Mauro TM, Wakefield JS, Menon G, Mauldin E, Miner JH, Lin MH, Brash AR, Sprecher E, Radner FPW, Choate K, Roop D, Uchida Y, Gruber R, Schmuth M, Elias PM (2018)
Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte Lipid Envelope
J Invest Dermatol, 139 (4), 760-768
DOI 10.1016/j.jid.2018.11.005, PubMed 30471252

de la Rosa Carrillo D, Sikorski K, Khnykin D, Wu W, Lund-Johansen F (2018)
High-resolution antibody array analysis of proteins from primary human keratinocytes and leukocytes
PLoS One, 13 (12), e0209271
DOI 10.1371/journal.pone.0209271, PubMed 30589857

Mauldin EA, Crumrine D, Casal ML, Jeong S, Opálka L, Vavrova K, Uchida Y, Park K, Craiglow B, Choate KA, Shin KO, Lee YM, Grove GL, Wakefield JS, Khnykin D, Elias PM (2018)
Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)-Deficient Canines
Am J Pathol, 188 (6), 1419-1429
DOI 10.1016/j.ajpath.2018.02.008, PubMed 29548991

Pietka W, Khnykin D, Bertelsen V, Lossius AH, Stav-Noraas TE, Hol Fosse J, Galtung HK, Haraldsen G, Sundnes O (2018)
Hypo-osmotic Stress Drives IL-33 Production in Human Keratinocytes-An Epidermal Homeostatic Response
J Invest Dermatol, 139 (1), 81-90
DOI 10.1016/j.jid.2018.07.023, PubMed 30120934

Publications 2017

Koppes SA, Engebretsen KA, Agner T, Angelova-Fischer I, Berents T, Brandner J, Brans R, Clausen ML, Hummler E, Jakasa I, Jurakić-Tončic R, John SM, Khnykin D, Molin S, Holm JO, Suomela S, Thierse HJ, Kezic S, Martin SF, Thyssen JP (2017)
Current knowledge on biomarkers for contact sensitization and allergic contact dermatitis
Contact Dermatitis, 77 (1), 1-16
DOI 10.1111/cod.12789, PubMed 28497472

Publications 2015

George R, Santhanam S, Samuel R, Chapla A, Hilmarsen HT, Braathen GJ, Reinholt FP, Jahnsen F, Khnykin D (2015)
Ichthyosis prematurity syndrome caused by a novel missense mutation in FATP4 gene-a case report from India
Clin Case Rep, 4 (1), 87-9
DOI 10.1002/ccr3.462, PubMed 26783444

Sundnes O, Pietka W, Loos T, Sponheim J, Rankin AL, Pflanz S, Bertelsen V, Sitek JC, Hol J, Haraldsen G, Khnykin D (2015)
Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences
J Invest Dermatol, 135 (7), 1771-1780
DOI 10.1038/jid.2015.85, PubMed 25739051

Publications 2013

Lin MH, Khnykin D (2013)
Fatty acid transporters in skin development, function and disease
Biochim Biophys Acta, 1841 (3), 362-8
DOI 10.1016/j.bbalip.2013.09.016, PubMed 24120574

Publications 2012

Blaas HG, Salvesen KÅ, Khnykin D, Jahnsen FL, Eik-Nes SH (2012)
Prenatal sonographic assessment and perinatal course of ichthyosis prematurity syndrome
Ultrasound Obstet Gynecol, 39 (4), 473-7
DOI 10.1002/uog.9014, PubMed 21465607

Lin C, Hindes A, Burns CJ, Koppel AC, Kiss A, Yin Y, Ma L, Blumenberg M, Khnykin D, Jahnsen FL, Crosby SD, Ramanan N, Efimova T (2012)
Serum response factor controls transcriptional network regulating epidermal function and hair follicle morphogenesis
J Invest Dermatol, 133 (3), 608-617
DOI 10.1038/jid.2012.378, PubMed 23151848

Publications 2011

Inhoff O, Hausser I, Schneider SW, Khnykin D, Jahnsen FL, Sartoris J, Goerdt S, Peitsch WK (2011)
Ichthyosis prematurity syndrome caused by a novel fatty acid transport protein 4 gene mutation in a German infant
Arch Dermatol, 147 (6), 750-2
DOI 10.1001/archdermatol.2011.139, PubMed 21690550

Khnykin D, Miner JH, Jahnsen F (2011)
Role of fatty acid transporters in epidermis: Implications for health and disease
Dermatoendocrinol, 3 (2), 53-61
DOI 10.4161/derm.3.2.14816, PubMed 21695012

Khnykin D, Rønnevig J, Johnsson M, Sitek JC, Blaas HG, Hausser I, Johansen FE, Jahnsen FL (2011)
Ichthyosis prematurity syndrome: clinical evaluation of 17 families with a rare disorder of lipid metabolism
J Am Acad Dermatol, 66 (4), 606-16
DOI 10.1016/j.jaad.2011.04.014, PubMed 21856041

Publications 2006

Khnykin D (2006)
Fibroblast growth factor receptors: role in intracellular trafficking and in diseases
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 395, 1 b. (flere pag.)
BIBSYS 060680989, ISBN 82-8072-217-3

Khnykin D, Olsnes S (2006)
Reduced binding of FGF1 to mutant fibroblast growth factor receptor 3
Growth Factors, 24 (2), 111-9
DOI 10.1080/08977190600621388, PubMed 16801131

Khnykin D, Troen G, Berner JM, Delabie J (2006)
The expression of fibroblast growth factors and their receptors in Hodgkin's lymphoma
J Pathol, 208 (3), 431-8
DOI 10.1002/path.1900, PubMed 16353171

Sørensen V, Wiedlocha A, Haugsten EM, Khnykin D, Wesche J, Olsnes S (2006)
Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail
J Cell Sci, 119 (Pt 20), 4332-41
DOI 10.1242/jcs.03209, PubMed 17003104

Publications 2004

Sørensen V, Brech A, Khnykin D, Kolpakova E, Citores L, Olsnes S (2004)
Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus
J Cell Sci, 117 (Pt 9), 1807-19
DOI 10.1242/jcs.01047, PubMed 15075241

Publications 2001

Citores L, Khnykin D, Sørensen V, Wesche J, Klingenberg O, Wiedłocha A, Olsnes S (2001)
Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain
J Cell Sci, 114 (Pt 9), 1677-89
PubMed 11398757

Publications 2000

Klingenberg O, Wiedlocha A, Rapak A, Khnykin D, Citores L, Olsnes S (2000)
Requirement for C-terminal end of fibroblast growth factor receptor 4 in translocation of acidic fibroblast growth factor to cytosol and nucleus
J Cell Sci, 113 ( Pt 10), 1827-38
PubMed 10769213

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