Publications 2024

Majid U, Bergsland CH, Sveen A, Bruun J, Eilertsen IA, Bækkevold ES, Nesbakken A, Yaqub S, Jahnsen FL, Lothe RA (2024)
The prognostic effect of tumor-associated macrophages in stage I-III colorectal cancer depends on T cell infiltration
Cell Oncol (Dordr) (in press)
DOI 10.1007/s13402-024-00926-w, PubMed 38407700

Publications 2023

Chauhan SK, Bartolomé Casado R, Landsverk OJB, Johannessen H, Phung D, Nilsen HR, Sætre F, Jahnsen J, Horneland R, Yaqub S, Aandahl EM, Lundin KEA, Bækkevold ES, Jahnsen FL (2023)
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
J Allergy Clin Immunol, 152 (1), 278-289.e6
DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861

Zilbauer M, James KR, Kaur M, Pott S, Li Z, Burger A, Thiagarajah JR, Burclaff J, Jahnsen FL, Perrone F, Ross AD, Matteoli G, Stakenborg N, Sujino T, Moor A, Bartolome-Casado R, Bækkevold ES, Zhou R, Xie B, Lau KS, Din S, Magness ST, Yao Q, Beyaz S, Arends M et al. (2023)
A Roadmap for the Human Gut Cell Atlas
Nat Rev Gastroenterol Hepatol, 20 (9), 597-614
DOI 10.1038/s41575-023-00784-1, PubMed 37258747

Publications 2022

Atlasy N, Bujko A, Bækkevold ES, Brazda P, Janssen-Megens E, Lundin KEA, Jahnsen J, Jahnsen FL, Stunnenberg HG (2022)
Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease
Nat Commun, 13 (1), 4920
DOI 10.1038/s41467-022-32691-5, PubMed 35995787

Balta MG, Schreurs O, Halder R, Küntziger TM, Saetre F, Blix IJS, Baekkevold ES, Glaab E, Schenck K (2022)
RvD1_{n-3 DPA} Downregulates the Transcription of Pro-Inflammatory Genes in Oral Epithelial Cells and Reverses Nuclear Translocation of Transcription Factor p65 after TNF-α Stimulation
Int J Mol Sci, 23 (23)
DOI 10.3390/ijms232314878, PubMed 36499208

Balta MG, Schreurs O, Hansen TV, Tungen JE, Vik A, Glaab E, Küntziger TM, Schenck K, Baekkevold ES, Blix IJS (2022)
Expression and function of resolvin RvD1_{n-3 DPA} receptors in oral epithelial cells
Eur J Oral Sci, 130 (4), e12883
DOI 10.1111/eos.12883, PubMed 35808844

Domanska D, Majid U, Karlsen VT, Merok MA, Beitnes AR, Yaqub S, Bækkevold ES, Jahnsen FL (2022)
Single-cell transcriptomic analysis of human colonic macrophages reveals niche-specific subsets
J Exp Med, 219 (3)
DOI 10.1084/jem.20211846, PubMed 35139155

Umu SU, Rapp Vander-Elst K, Karlsen VT, Chouliara M, Bækkevold ES, Jahnsen FL, Domanska D (2022)
Cellsnake: a user-friendly tool for single-cell RNA sequencing analysis
Gigascience, 12
DOI 10.1093/gigascience/giad091, PubMed 37889009

Aasebo AT, Gedde-Dahl T, Reims HM, Baekkevold ES, Jahnsen FL (2022)
Calprotectin Expressing Donor-Derived Macrophages Increase in Acute Gastrointestinal Graft-Versus-Host Disease
Transplant Cell Ther, 28 (5), 248.e1-248.e8
DOI 10.1016/j.jtct.2022.01.028, PubMed 35144036

Publications 2021

Bartolomé-Casado R, Bækkevold ES, Jahnsen FL (2021)
Response to Lauro and Zorzetti
Mucosal Immunol, 14 (6), 1395-1396
DOI 10.1038/s41385-021-00454-y, PubMed 34535772

Sikkeland LIB, Qiao SW, Ueland T, Myrdal O, Wyrożemski Ł, Aukrust P, Jahnsen FL, Sjåheim T, Kongerud J, Molberg Ø, Lund MB, Bækkevold ES (2021)
Lung CD4+ T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-γ
Eur Respir J, 57 (3)
DOI 10.1183/13993003.00983-2020, PubMed 33154027

Solhaug MB, Schreurs O, Schenck K, Blix IJ, Baekkevold ES (2021)
Origin of langerin (CD207)-expressing antigen presenting cells in the normal oral mucosa and in oral lichen planus lesions
Eur J Oral Sci, 130 (1), e12835
DOI 10.1111/eos.12835, PubMed 34935212

Publications 2020

Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Sætre F, Hagen KT, Yaqub S, Øyen O, Horneland R, Aandahl EM, Aabakken L, Bækkevold ES, Jahnsen FL (2020)
CD4⁺ T cells persist for years in the human small intestine and display a T_H1 cytokine profile
Mucosal Immunol, 14 (2), 402-410
DOI 10.1038/s41385-020-0315-5, PubMed 32572129

Bern M, Nilsen J, Ferrarese M, Sand KMK, Gjølberg TT, Lode HE, Davidson RJ, Camire RM, Bækkevold ES, Foss S, Grevys A, Dalhus B, Wilson J, Høydahl LS, Christianson GJ, Roopenian DC, Schlothauer T, Michaelsen TE, Moe MC, Lombardi S, Pinotti M, Sandlie I, Branchini A, Andersen JT (2020)
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics
Sci Transl Med, 12 (565)
DOI 10.1126/scitranslmed.abb0580, PubMed 33055243

Divito SJ, Aasebø AT, Matos TR, Hsieh PC, Collin M, Elco CP, O'Malley JT, Bækkevold ES, Reims H, Gedde-Dahl T, Hagerstrom M, Hilaire J, Lian JW, Milford EL, Pinkus GS, Ho VT, Soiffer RJ, Kim HT, Mihm MC, Ritz J, Guleria I, Cutler CS, Clark RA, Jahnsen FL, Kupper TS (2020)
Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease
J Clin Invest, 130 (9), 4624-4636
DOI 10.1172/JCI129965, PubMed 32516138

Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393

Publications 2019

Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Richter L, Phung D, Greiff V, Risnes LF, Yao Y, Neumann RS, Yaqub S, Øyen O, Horneland R, Aandahl EM, Paulsen V, Sollid LM, Qiao SW, Baekkevold ES, Jahnsen FL (2019)
Resident memory CD8 T cells persist for years in human small intestine
J Exp Med, 216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737

Cassetta L, Baekkevold ES, Brandau S, Bujko A, Cassatella MA, Dorhoi A, Krieg C, Lin A, Loré K, Marini O, Pollard JW, Roussel M, Scapini P, Umansky V, Adema GJ (2019)
Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates
Cancer Immunol Immunother, 68 (4), 687-697
DOI 10.1007/s00262-019-02302-2, PubMed 30684003

Stankovic B, Bjørhovde HAK, Skarshaug R, Aamodt H, Frafjord A, Müller E, Hammarström C, Beraki K, Bækkevold ES, Woldbæk PR, Helland Å, Brustugun OT, Øynebråten I, Corthay A (2019)
Immune Cell Composition in Human Non-small Cell Lung Cancer
Front Immunol, 9, 3101
DOI 10.3389/fimmu.2018.03101, PubMed 30774636

Publications 2018

Eguíluz-Gracia I, Malmstrom K, Dheyauldeen SA, Lohi J, Sajantila A, Aaløkken R, Sundaram AYM, Gilfillan GD, Makela M, Baekkevold ES, Jahnsen FL (2018)
Monocytes accumulate in the airways of children with fatal asthma
Clin Exp Allergy, 48 (12), 1631-1639
DOI 10.1111/cea.13265, PubMed 30184280

Poulsen LC, Edelmann RJ, Krüger S, Diéguez-Hurtado R, Shah A, Stav-Noraas TE, Renzi A, Szymanska M, Wang J, Ehling M, Benedito R, Kasprzycka M, Bækkevold E, Sundnes O, Midwood KS, Scott H, Collas P, Siebel CW, Adams RH, Haraldsen G, Sundlisæter E, Hol J (2018)
Inhibition of Endothelial NOTCH1 Signaling Attenuates Inflammation by Reducing Cytokine-Mediated Histone Acetylation at Inflammatory Enhancers
Arterioscler Thromb Vasc Biol, 38 (4), 854-869
DOI 10.1161/ATVBAHA.117.310388, PubMed 29449332

Richter L, Landsverk OJB, Atlasy N, Bujko A, Yaqub S, Horneland R, Øyen O, Aandahl EM, Lundin KEA, Stunnenberg HG, Bækkevold ES, Jahnsen FL (2018)
Transcriptional profiling reveals monocyte-related macrophages phenotypically resembling DC in human intestine
Mucosal Immunol, 11 (5), 1512-1523
DOI 10.1038/s41385-018-0060-1, PubMed 30038215

Publications 2017

Bujko A, Atlasy N, Landsverk OJB, Richter L, Yaqub S, Horneland R, Øyen O, Aandahl EM, Aabakken L, Stunnenberg HG, Bækkevold ES, Jahnsen FL (2017)
Transcriptional and functional profiling defines human small intestinal macrophage subsets
J Exp Med, 215 (2), 441-458
DOI 10.1084/jem.20170057, PubMed 29273642

Engen SA, Schreurs O, Petersen F, Blix IJS, Baekkevold ES, Schenck K (2017)
The Regulatory Role of the Oral Commensal Streptococcus mitis on Human Monocytes
Scand J Immunol, 87 (2), 80-87
DOI 10.1111/sji.12636, PubMed 29194752

Gudjonsson A, Lysén A, Balan S, Sundvold-Gjerstad V, Arnold-Schrauf C, Richter L, Bækkevold ES, Dalod M, Bogen B, Fossum E (2017)
Targeting Influenza Virus Hemagglutinin to Xcr1⁺ Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses
J Immunol, 198 (7), 2785-2795
DOI 10.4049/jimmunol.1601881, PubMed 28228559

Jahnsen FL, Bækkevold ES, Hov JR, Landsverk OJ (2017)
Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?
Trends Immunol, 39 (3), 196-208
DOI 10.1016/j.it.2017.10.006, PubMed 29162322

Landsverk OJ, Snir O, Casado RB, Richter L, Mold JE, Réu P, Horneland R, Paulsen V, Yaqub S, Aandahl EM, Øyen OM, Thorarensen HS, Salehpour M, Possnert G, Frisén J, Sollid LM, Baekkevold ES, Jahnsen FL (2017)
Antibody-secreting plasma cells persist for decades in human intestine
J Exp Med, 214 (2), 309-317
DOI 10.1084/jem.20161590, PubMed 28104812

Publications 2016

Ballke C, Gran E, Baekkevold ES, Jahnsen FL (2016)
Characterization of Regulatory T-Cell Markers in CD4+ T Cells of the Upper Airway Mucosa
PLoS One, 11 (2), e0148826
DOI 10.1371/journal.pone.0148826, PubMed 26866695

Eguíluz-Gracia I, Bosco A, Dollner R, Melum GR, Lexberg MH, Jones AC, Dheyauldeen SA, Holt PG, Bækkevold ES, Jahnsen FL (2016)
Rapid recruitment of CD14(+) monocytes in experimentally induced allergic rhinitis in human subjects
J Allergy Clin Immunol, 137 (6), 1872-1881.e12
DOI 10.1016/j.jaci.2015.11.025, PubMed 26851967

Eguíluz-Gracia I, Schultz HH, Sikkeland LI, Danilova E, Holm AM, Pronk CJ, Agace WW, Iversen M, Andersen C, Jahnsen FL, Baekkevold ES (2016)
Long-term persistence of human donor alveolar macrophages in lung transplant recipients
Thorax, 71 (11), 1006-1011
DOI 10.1136/thoraxjnl-2016-208292, PubMed 27329043

Schrøder M, Melum GR, Landsverk OJ, Bujko A, Yaqub S, Gran E, Aamodt H, Bækkevold ES, Jahnsen FL, Richter L (2016)
CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits
PLoS One, 11 (6), e0157387
DOI 10.1371/journal.pone.0157387, PubMed 27311059

Publications 2015

Skrindo I, Ballke C, Gran E, Johansen FE, Baekkevold ES, Jahnsen FL (2015)
IL-5 production by resident mucosal allergen-specific T cells in an explant model of allergic rhinitis
Clin Exp Allergy, 45 (8), 1296-304
DOI 10.1111/cea.12543, PubMed 25817862

Publications 2014

Bjerkan L, Schreurs O, Engen SA, Jahnsen FL, Baekkevold ES, Blix IJ, Schenck K (2014)
The short form of TSLP is constitutively translated in human keratinocytes and has characteristics of an antimicrobial peptide
Mucosal Immunol, 8 (1), 49-56
DOI 10.1038/mi.2014.41, PubMed 24850429

Danilova E, Skrindo I, Gran E, Hales BJ, Smith WA, Jahnsen J, Johansen FE, Jahnsen FL, Baekkevold ES (2014)
A role for CCL28-CCR3 in T-cell homing to the human upper airway mucosa
Mucosal Immunol, 8 (1), 107-14
DOI 10.1038/mi.2014.46, PubMed 24917456

Melum GR, Farkas L, Scheel C, Van Dieren B, Gran E, Liu YJ, Johansen FE, Jahnsen FL, Baekkevold ES (2014)
A thymic stromal lymphopoietin-responsive dendritic cell subset mediates allergic responses in the upper airway mucosa
J Allergy Clin Immunol, 134 (3), 613-621.e7
DOI 10.1016/j.jaci.2014.05.010, PubMed 24958565

Solberg LB, Brorson SH, Stordalen GA, Bækkevold ES, Andersson G, Reinholt FP (2014)
Increased tartrate-resistant Acid phosphatase expression in osteoblasts and osteocytes in experimental osteoporosis in rats
Calcif Tissue Int, 94 (5), 510-21
DOI 10.1007/s00223-013-9834-3, PubMed 24395179

Publications 2013

Hessle L, Stordalen GA, Wenglén C, Petzold C, Tanner E, Brorson SH, Baekkevold ES, Önnerfjord P, Reinholt FP, Heinegård D (2013)
The skeletal phenotype of chondroadherin deficient mice
PLoS One, 8 (6), e63080
DOI 10.1371/journal.pone.0063080, PubMed 23755099

Publications 2011

Schiøtz BL, Rosado EG, Baekkevold ES, Lukacs M, Mjaaland S, Sindre H, Grimholt U, Gjøen T (2011)
Enhanced transfection of cell lines from Atlantic salmon through nucoleofection and antibiotic selection
BMC Res Notes, 4, 136
DOI 10.1186/1756-0500-4-136, PubMed 21548922

Publications 2010

Melhus G, Brorson SH, Baekkevold ES, Andersson G, Jemtland R, Olstad OK, Reinholt FP (2010)
Gene expression and distribution of key bone turnover markers in the callus of estrogen-deficient, vitamin D-depleted rats
Calcif Tissue Int, 87 (1), 77-89
DOI 10.1007/s00223-010-9371-2, PubMed 20495792

Publications 2009

Schiøtz BL, Baekkevold ES, Poulsen LC, Mjaaland S, Gjøen T (2009)
Analysis of host- and strain-dependent cell death responses during infectious salmon anemia virus infection in vitro
Virol J, 6, 91
DOI 10.1186/1743-422X-6-91, PubMed 19566966

Publications 2008

García-Rosado E, Markussen T, Kileng O, Baekkevold ES, Robertsen B, Mjaaland S, Rimstad E (2008)
Molecular and functional characterization of two infectious salmon anaemia virus (ISAV) proteins with type I interferon antagonizing activity
Virus Res, 133 (2), 228-38
DOI 10.1016/j.virusres.2008.01.008, PubMed 18304672

Publications 2005

Baekkevold ES, Wurbel MA, Kivisäkk P, Wain CM, Power CA, Haraldsen G, Campbell JJ (2005)
A role for CCR4 in development of mature circulating cutaneous T helper memory cell populations
J Exp Med, 201 (7), 1045-51
DOI 10.1084/jem.20041059, PubMed 15795234

Carlsen HS, Haraldsen G, Brandtzaeg P, Baekkevold ES (2005)
Disparate lymphoid chemokine expression in mice and men: no evidence of CCL21 synthesis by human high endothelial venules
Blood, 106 (2), 444-6
DOI 10.1182/blood-2004-11-4353, PubMed 15863780

Johansen FE, Baekkevold ES, Carlsen HS, Farstad IN, Soler D, Brandtzaeg P (2005)
Regional induction of adhesion molecules and chemokine receptors explains disparate homing of human B cells to systemic and mucosal effector sites: dispersion from tonsils
Blood, 106 (2), 593-600
DOI 10.1182/blood-2004-12-4630, PubMed 15827133

Publications 2004

Brandtzaeg P, Johansen FE, Baekkevold ES, Carlsen HS, Farstad IN (2004)
The traffic of mucosal lymphocytes to extraintestinal sites
J Pediatr Gastroenterol Nutr, 39 Suppl 3, S725-6
DOI 10.1097/00005176-200406003-00004, PubMed 15167361

Carlsen HS, Baekkevold ES, Morton HC, Haraldsen G, Brandtzaeg P (2004)
Monocyte-like and mature macrophages produce CXCL13 (B cell-attracting chemokine 1) in inflammatory lesions with lymphoid neogenesis
Blood, 104 (10), 3021-7
DOI 10.1182/blood-2004-02-0701, PubMed 15284119

Lacorre DA, Baekkevold ES, Garrido I, Brandtzaeg P, Haraldsen G, Amalric F, Girard JP (2004)
Plasticity of endothelial cells: rapid dedifferentiation of freshly isolated high endothelial venule endothelial cells outside the lymphoid tissue microenvironment
Blood, 103 (11), 4164-72
DOI 10.1182/blood-2003-10-3537, PubMed 14976058

Publications 2003

Baekkevold ES, Roussigné M, Yamanaka T, Johansen FE, Jahnsen FL, Amalric F, Brandtzaeg P, Erard M, Haraldsen G, Girard JP (2003)
Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules
Am J Pathol, 163 (1), 69-79
DOI 10.1016/S0002-9440(10)63631-0, PubMed 12819012

Kivisäkk P, Mahad DJ, Callahan MK, Trebst C, Tucky B, Wei T, Wu L, Baekkevold ES, Lassmann H, Staugaitis SM, Campbell JJ, Ransohoff RM (2003)
Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin
Proc Natl Acad Sci U S A, 100 (14), 8389-94
DOI 10.1073/pnas.1433000100, PubMed 12829791

Weninger W, Carlsen HS, Goodarzi M, Moazed F, Crowley MA, Baekkevold ES, Cavanagh LL, von Andrian UH (2003)
Naive T cell recruitment to nonlymphoid tissues: a role for endothelium-expressed CC chemokine ligand 21 in autoimmune disease and lymphoid neogenesis
J Immunol, 170 (9), 4638-48
DOI 10.4049/jimmunol.170.9.4638, PubMed 12707342

Publications 2002

Carlsen HS, Baekkevold ES, Johansen FE, Haraldsen G, Brandtzaeg P (2002)
B cell attracting chemokine 1 (CXCL13) and its receptor CXCR5 are expressed in normal and aberrant gut associated lymphoid tissue
Gut, 51 (3), 364-71
DOI 10.1136/gut.51.3.364, PubMed 12171958

Publications 2001

Baekkevold ES, Yamanaka T, Palframan RT, Carlsen HS, Reinholt FP, von Andrian UH, Brandtzaeg P, Haraldsen G (2001)
The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment
J Exp Med, 193 (9), 1105-12
DOI 10.1084/jem.193.9.1105, PubMed 11342595

Brandtzaeg P, Baekkevold ES, Morton HC (2001)
From B to A the mucosal way
Nat Immunol, 2 (12), 1093-4
DOI 10.1038/ni1201-1093, PubMed 11725295

Publications 1999

Baekkevold ES, Jahnsen FL, Johansen FE, Bakke O, Gaudernack G, Brandtzaeg P, Haraldsen G (1999)
Culture characterization of differentiated high endothelial venule cells from human tonsils
Lab Invest, 79 (3), 327-36
PubMed 10092069

Brandtzaeg P, Baekkevold ES, Farstad IN, Jahnsen FL, Johansen FE, Nilsen EM, Yamanaka T (1999)
Regional specialization in the mucosal immune system: what happens in the microcompartments?
Immunol Today, 20 (3), 141-51
DOI 10.1016/s0167-5699(98)01413-3, PubMed 10203706

Girard JP, Baekkevold ES, Feliu J, Brandtzaeg P, Amalric F (1999)
Molecular cloning and functional analysis of SUT-1, a sulfate transporter from human high endothelial venules
Proc Natl Acad Sci U S A, 96 (22), 12772-7
DOI 10.1073/pnas.96.22.12772, PubMed 10535998

Girard JP, Baekkevold ES, Yamanaka T, Haraldsen G, Brandtzaeg P, Amalric F (1999)
Heterogeneity of endothelial cells: the specialized phenotype of human high endothelial venules characterized by suppression subtractive hybridization
Am J Pathol, 155 (6), 2043-55
DOI 10.1016/S0002-9440(10)65523-X, PubMed 10595934

Publications 1998

Girard JP, Baekkevold ES, Amalric F (1998)
Sulfation in high endothelial venules: cloning and expression of the human PAPS synthetase
FASEB J, 12 (7), 603-12
DOI 10.1096/fasebj.12.7.603, PubMed 9576487