Projects

  • Developmental and functional characterization of NK cell subsets and ILCs in different tissues in the rat, and their role in acute graft versus host disease.
  • Evaluation of exosomes as early prognostic markers for risk stratification of pediatric acute leukemia.
  • In-depth mechanistic studies of how NK cells may be manipulated to target leukemia blasts using in vivo rat models of T-ALL and AML.
  • Characterization of intracellular signaling cascades in human NK cells.
 
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