Publications
Publications published since 2000 from OUS - Department of Cancer Immunology
713 publications found
Publications 2024
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Machine Learning Made Easy (MLme): a comprehensive toolkit for machine learning-driven data analysis
Gigascience, 13
DOI 10.1093/gigascience/giad111, PubMed 38206587 -
Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors - a biomarker analysis of the ALICE and ICON trials
Mol Oncol (in press)
DOI 10.1002/1878-0261.13675, PubMed 38978352 -
Ipilimumab and nivolumab combined with anthracycline-based chemotherapy in metastatic hormone receptor-positive breast cancer: a randomized phase 2b trial
J Immunother Cancer, 12 (1)
DOI 10.1136/jitc-2023-007990, PubMed 38242720 -
MetaGate: Interactive analysis of high-dimensional cytometry data with metadata integration
Patterns (N Y), 5 (7), 100989
DOI 10.1016/j.patter.2024.100989, PubMed 39081571 -
Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma
Blood Cancer J, 14 (1), 147
DOI 10.1038/s41408-024-01124-5, PubMed 39191762 -
Cell surface marker heterogeneity in human myeloma cell lines for modeling of disease and therapy
Sci Rep, 14 (1), 28805
DOI 10.1038/s41598-024-80263-y, PubMed 39567630 -
Patient-derived acellular ascites fluid affects drug responses in ovarian cancer cell lines through the activation of key signalling pathways
Mol Oncol (in press)
DOI 10.1002/1878-0261.13726, PubMed 39245677 -
Acta Oncologica Nordic Precision Cancer Medicine Symposium 2023 - merging clinical research and standard healthcare
Acta Oncol, 63, 487-490
DOI 10.2340/1651-226X.2024.24954, PubMed 38910311 -
Peripheral immune cells in metastatic breast cancer patients display a systemic immunosuppressed signature consistent with chronic inflammation
NPJ Breast Cancer, 10 (1), 30
DOI 10.1038/s41523-024-00638-2, PubMed 38653982 -
Impact of Rare Structural Variant Events in Newly Diagnosed Multiple Myeloma
Clin Cancer Res, 30 (3), 575-585
DOI 10.1158/1078-0432.CCR-23-1045, PubMed 37939148 -
The function of the complement system remains fully intact throughout the course of allogeneic stem cell transplantation
Front Immunol, 15, 1422370
DOI 10.3389/fimmu.2024.1422370, PubMed 38938578 -
Systematic evaluation of donor-KIR/recipient-HLA interactions in HLA-matched hematopoietic cell transplantation for AML
Blood Adv, 8 (3), 581-590
DOI 10.1182/bloodadvances.2023011622, PubMed 38052043 -
T cells with increased responsiveness cause obesity in mice without diet intervention
iScience, 27 (4), 109471
DOI 10.1016/j.isci.2024.109471, PubMed 38551005 -
Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
Cell Stem Cell, 31 (9), 1376-1386.e8
DOI 10.1016/j.stem.2024.06.011, PubMed 38981470 -
[Raising the quality of cancer treatment]
Tidsskr Nor Laegeforen, 144 (1)
DOI 10.4045/tidsskr.23.0740, PubMed 38258713 -
Immunophenotyping with (phospho)protein profiling and fluorescent cell barcoding for single-cell signaling analysis and biomarker discovery
NPJ Precis Oncol, 8 (1), 107
DOI 10.1038/s41698-024-00604-y, PubMed 38769096 -
CD38 regulates chronic lymphocytic leukemia proliferation via CD45 phosphatase activity
Mol Ther Oncol, 32 (3), 200841
DOI 10.1016/j.omton.2024.200841, PubMed 39474602 -
Comparative Evaluation of STEAP1 Targeting Chimeric Antigen Receptors with Different Costimulatory Domains and Spacers
Int J Mol Sci, 25 (1)
DOI 10.3390/ijms25010586, PubMed 38203757 -
Correction: Jin et al. Comparative Evaluation of STEAP1 Targeting Chimeric Antigen Receptors with Different Costimulatory Domains and Spacers. Int. J. Mol. Sci. 2024, 25, 586
Int J Mol Sci, 25 (18)
DOI 10.3390/ijms251810024, PubMed 39337718 -
IUIS 2023: yEFIS workshop on career development and code-switching
Eur J Immunol, 54 (7), e2451155
DOI 10.1002/eji.202451155, PubMed 38676471 -
Plasma protein dynamics during ipilimumab treatment in metastatic melanoma: associations with tumor response, adverse events and survival
Oncoimmunology, 14 (1), 2440967
DOI 10.1080/2162402X.2024.2440967, PubMed 39703053 -
Engineering immune-evasive allogeneic cellular immunotherapies
Nat Rev Immunol, 24 (9), 680-693
DOI 10.1038/s41577-024-01022-8, PubMed 38658708 -
Disruption of KLHL6 Fuels Oncogenic Antigen Receptor Signaling in B-Cell Lymphoma
Blood Cancer Discov, 5 (5), 331-352
DOI 10.1158/2643-3230.BCD-23-0182, PubMed 38630892 -
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127
Science, 383 (6682), eadi5798
DOI 10.1126/science.adi5798, PubMed 38301010 -
Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping
Nat Immunol, 25 (8), 1445-1459
DOI 10.1038/s41590-024-01884-z, PubMed 38956379 -
circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA
bioRxiv
DOI 10.1101/2023.09.14.557527, PubMed 37745562 -
The Tumor Immune Microenvironment in Breast Cancer Progression
Acta Oncol, 63, 359-367
DOI 10.2340/1651-226X.2024.33008, PubMed 38779867 -
The G Protein-Coupled Receptor GPR56 Is an Inhibitory Checkpoint for NK Cell Migration
J Immunol, 213 (9), 1349-1357
DOI 10.4049/jimmunol.2400228, PubMed 39320215 -
Egr2 to the rescue: nanoparticles revitalize natural killer cells in the fight against cancer
EMBO J, 43 (13), 2527-2529
DOI 10.1038/s44318-024-00144-y, PubMed 38886578 -
IMPRESS-Norway: improving public cancer care by implementing precision medicine in Norway; inclusion rates and preliminary results
Acta Oncol, 63, 379-384
DOI 10.2340/1651-226X.2024.28322, PubMed 38779911 -
High-dimensional single-cell analysis of human natural killer cell heterogeneity
Nat Immunol, 25 (8), 1474-1488
DOI 10.1038/s41590-024-01883-0, PubMed 38956378 -
Exploring the Impact of mRNA Modifications on Translation Efficiency and Immune Tolerance to Self-Antigens
Vaccines (Basel), 12 (6)
DOI 10.3390/vaccines12060624, PubMed 38932353 -
PI3K Inhibitors in Hematology: When One Door Closes…
Clin Cancer Res, 30 (17), 3667-3675
DOI 10.1158/1078-0432.CCR-24-0967, PubMed 38967552 -
Citalopram exposure of hESCs during neuronal differentiation identifies dysregulated genes involved in neurodevelopment and depression
Front Cell Dev Biol, 12, 1428538
DOI 10.3389/fcell.2024.1428538, PubMed 39055655 -
The HLA-B -21 M/T dimorphism associates with disease severity in COVID-19
Genes Immun (in press)
DOI 10.1038/s41435-024-00302-6, PubMed 39487235 -
Evolutionary mode and timing of dissemination of high-grade serous carcinomas
JCI Insight, 9 (3)
DOI 10.1172/jci.insight.170423, PubMed 38175731 -
Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor
Med (in press)
DOI 10.1016/j.medj.2024.09.010, PubMed 39423821 -
PCM4EU and PRIME-ROSE: Collaboration for implementation of precision cancer medicine in Europe
Acta Oncol, 63, 385-391
DOI 10.2340/1651-226X.2024.34791, PubMed 38779910 -
Gut microbiota diversity is prognostic and associated with benefit from chemo-immunotherapy in metastatic triple-negative breast cancer
Mol Oncol (in press)
DOI 10.1002/1878-0261.13760, PubMed 39545921 -
A temporal developmental map separates human NK cells from noncytotoxic ILCs through clonal and single-cell analysis
Blood Adv, 8 (11), 2933-2951
DOI 10.1182/bloodadvances.2023011909, PubMed 38484189 -
Interleukin-12 decorated nanosized semiflexible Immunofilaments enable directed targeting and augmented IFNγ responses of natural killer cells
Acta Biomater, 191, 386-397
DOI 10.1016/j.actbio.2024.11.012, PubMed 39528061 -
Changes in AXL and/or MITF melanoma subpopulations in patients receiving immunotherapy
Immunooncol Technol, 24, 101009
DOI 10.1016/j.iotech.2024.101009, PubMed 39697983
Publications 2023
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Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis
bioRxiv
DOI 10.1101/2023.07.04.546825, PubMed 37461685 -
Clinical forecasting of acute myeloid leukemia using ex vivo drug-sensitivity profiling
Cell Rep Methods, 3 (12), 100654
DOI 10.1016/j.crmeth.2023.100654, PubMed 38065095 -
MetaGate: Interactive Analysis of High-Dimensional Cytometry Data with Meta Data Integration
bioRxiv
DOI 10.1101/2023.10.27.564454, PubMed 37961421 -
Standardized assays to monitor drug sensitivity in hematologic cancers
Cell Death Discov, 9 (1), 435
DOI 10.1038/s41420-023-01722-5, PubMed 38040674 -
Development of a TGFβ-IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy
Biomedicines, 11 (2)
DOI 10.3390/biomedicines11020459, PubMed 36830995 -
Multiomic Mapping of Acquired Chromosome 1 Copy-Number and Structural Variants to Identify Therapeutic Vulnerabilities in Multiple Myeloma
Clin Cancer Res, 29 (19), 3901-3913
DOI 10.1158/1078-0432.CCR-22-3209, PubMed 37449980 -
Efficient chimeric antigen receptor targeting of a central epitope of CD22
J Biol Chem, 299 (7), 104883
DOI 10.1016/j.jbc.2023.104883, PubMed 37269947 -
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
J Allergy Clin Immunol, 152 (1), 278-289.e6
DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861 -
Impact of rare structural variant events in newly diagnosed multiple myeloma
bioRxiv
DOI 10.1101/2023.01.03.522573, PubMed 36711679 -
The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk
J Immunol, 211 (9), 1348-1358
DOI 10.4049/jimmunol.2300406, PubMed 37737664 -
Therapeutic cancer vaccination against telomerase: clinical developments in melanoma
Curr Opin Oncol, 35 (2), 100-106
DOI 10.1097/CCO.0000000000000922, PubMed 36700456 -
A systematic safety pipeline for selection of T-cell receptors to enter clinical use
NPJ Vaccines, 8 (1), 126
DOI 10.1038/s41541-023-00713-y, PubMed 37607971 -
Small molecule inhibitors targeting regulatory T cells for cancer treatment
Eur J Immunol, 54 (2), e2350448
DOI 10.1002/eji.202350448, PubMed 37937687 -
Affibody-based hBCMA x CD16 dual engagers for NK cell-mediated killing of multiple myeloma cells
N Biotechnol, 77, 139-148
DOI 10.1016/j.nbt.2023.09.002, PubMed 37673373 -
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo
Nat Cancer, 4 (10), 1474-1490
DOI 10.1038/s43018-023-00642-8, PubMed 37783807 -
Genetic ablation of adhesion ligands averts rejection of allogeneic immune cells
bioRxiv
DOI 10.1101/2023.10.09.557143, PubMed 37873468 -
Effect of mTOR Inhibition with Sirolimus on Natural Killer Cell Reconstitution in Allogeneic Stem Cell Transplantation
Transplant Cell Ther, 29 (6), 376.e1-376.e11
DOI 10.1016/j.jtct.2023.03.023, PubMed 36966873 -
A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine
Cell Death Discov, 9 (1), 125
DOI 10.1038/s41420-023-01426-w, PubMed 37055391 -
Functional SARS-CoV-2 cross-reactive CD4+ T cells established in early childhood decline with age
Proc Natl Acad Sci U S A, 120 (12), e2220320120
DOI 10.1073/pnas.2220320120, PubMed 36917669 -
The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy
Haematologica, 108 (9), 2454-2466
DOI 10.3324/haematol.2022.282289, PubMed 36861406 -
Fludarabine plus reduced-intensity busulfan versus fludarabine plus myeloablative busulfan in patients with non-Hodgkin lymphoma undergoing allogeneic hematopoietic cell transplantation
Ann Hematol, 102 (3), 651-661
DOI 10.1007/s00277-023-05084-x, PubMed 36631705 -
Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data
Cell Rep Methods, 3 (3), 100417
DOI 10.1016/j.crmeth.2023.100417, PubMed 37056380 -
Mapping the chemotactic landscape in NK cells reveals subset-specific synergistic migratory responses to dual chemokine receptor ligation
EBioMedicine, 96, 104811
DOI 10.1016/j.ebiom.2023.104811, PubMed 37741009 -
Modified study designs to expand treatment options in personalised oncology: a multistakeholder view
Eur J Cancer, 194, 113278
DOI 10.1016/j.ejca.2023.113278, PubMed 37820553 -
ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma
Nat Commun, 14 (1), 3375
DOI 10.1038/s41467-023-39097-x, PubMed 37291203 -
Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants
Cell Rep, 42 (1), 111995
DOI 10.1016/j.celrep.2023.111995, PubMed 36656713 -
Allelic variation of KIR and HLA tunes the cytolytic payload and determines functional hierarchy of NK cell repertoires
Blood Adv, 7 (16), 4492-4504
DOI 10.1182/bloodadvances.2023009827, PubMed 37327114 -
Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection
Eur J Immunol, 53 (8), e2250254
DOI 10.1002/eji.202250254, PubMed 37102399 -
Modulation of lytic molecules restrain serial killing in γδ T lymphocytes
Nat Commun, 14 (1), 6035
DOI 10.1038/s41467-023-41634-7, PubMed 37758698 -
Extreme body mass index and survival in newly diagnosed multiple myeloma patients
Blood Cancer J, 13 (1), 13
DOI 10.1038/s41408-022-00782-7, PubMed 36631444 -
How the initial discovery of modified RNA enabled evasion of innate immune responses and facilitated the development of RNA therapeutics
Scand J Immunol, 98 (1), e13282
DOI 10.1111/sji.13282, PubMed 37132451 -
Antibody Surface Profiling Identifies Glycoforms in Multiple Myeloma as Targets for Immunotherapy: From Antibody Derivatives to Mimetic Peptides for Killing Tumor Cells
Cancers (Basel), 15 (7)
DOI 10.3390/cancers15071934, PubMed 37046595 -
Precision Killing of M2 Macrophages with Phage-Displayed Peptide-Photosensitizer Conjugates
Cancers (Basel), 15 (7)
DOI 10.3390/cancers15072009, PubMed 37046671 -
Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure
Circulation, 147 (16), 1221-1236
DOI 10.1161/CIRCULATIONAHA.121.054168, PubMed 36876489 -
PI3K inhibitors in chronic lymphocytic leukemia: where do we go from here?
Haematologica, 108 (1), 9-21
DOI 10.3324/haematol.2022.281266, PubMed 35899388 -
Diversity of intratumoral regulatory T cells in B-cell non-Hodgkin lymphoma
Blood Adv, 7 (23), 7216-7230
DOI 10.1182/bloodadvances.2023010158, PubMed 37695745 -
High-resolution alignment of single-cell and spatial transcriptomes with CytoSPACE
Nat Biotechnol, 41 (11), 1543-1548
DOI 10.1038/s41587-023-01697-9, PubMed 36879008 -
NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts
Blood, 141 (13), 1584-1596
DOI 10.1182/blood.2022016934, PubMed 36375120 -
Tumor-Associated Macrophage Subsets: Shaping Polarization and Targeting
Int J Mol Sci, 24 (8)
DOI 10.3390/ijms24087493, PubMed 37108657
Publications 2022
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Myeloperoxidase exerts anti-tumor activity in glioma after radiotherapy
Neoplasia, 26, 100779
DOI 10.1016/j.neo.2022.100779, PubMed 35247801 -
Approach to a patient with "double refractory" chronic lymphocytic leukemia: "Double, double toil and trouble" (Shakespeare)
Am J Hematol, 97 Suppl 2, S19-S25
DOI 10.1002/ajh.26682, PubMed 36125036 -
Computational Pipeline for Rational Drug Combination Screening in Patient-Derived Cells
Methods Mol Biol, 2449, 327-348
DOI 10.1007/978-1-0716-2095-3_14, PubMed 35507270 -
PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells
J Immunother Cancer, 10 (1)
DOI 10.1136/jitc-2021-002500, PubMed 35078921 -
Chasing neoantigens; invite naïve T cells to the party
Curr Opin Immunol, 75, 102172
DOI 10.1016/j.coi.2022.102172, PubMed 35279483 -
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma
Nat Commun, 13 (1), 7341
DOI 10.1038/s41467-022-35127-2, PubMed 36446823 -
Development of a High-Affinity Antibody against the Tumor-Specific and Hyperactive 611-p95HER2 Isoform
Cancers (Basel), 14 (19)
DOI 10.3390/cancers14194859, PubMed 36230782 -
Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
Trends Pharmacol Sci, 43 (11), 973-985
DOI 10.1016/j.tips.2022.08.009, PubMed 36163057 -
Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
Front Oncol, 12, 1040730
DOI 10.3389/fonc.2022.1040730, PubMed 36523963 -
Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically
Mol Oncol, 16 (6), 1241-1258
DOI 10.1002/1878-0261.13191, PubMed 35148457 -
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Cell Rep, 38 (10), 110503
DOI 10.1016/j.celrep.2022.110503, PubMed 35235832 -
Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia
J Immunother Cancer, 10 (11)
DOI 10.1136/jitc-2022-005577, PubMed 36319065 -
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 225
DOI 10.1186/s12967-022-03432-5, PubMed 35568909 -
Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 317
DOI 10.1186/s12967-022-03518-0, PubMed 35841045 -
Asporin, an extracellular matrix protein, is a beneficial regulator of cardiac remodeling
Matrix Biol, 110, 40-59
DOI 10.1016/j.matbio.2022.04.005, PubMed 35470068 -
Capture Rate of V(D)J Sequencing for Minimal Residual Disease Detection in Multiple Myeloma
Clin Cancer Res, 28 (10), 2160-2166
DOI 10.1158/1078-0432.CCR-20-2995, PubMed 35553646 -
Mechanism of CD79A and CD79B Support for IgM+ B Cell Fitness through B Cell Receptor Surface Expression
J Immunol, 209 (10), 2042-2053
DOI 10.4049/jimmunol.2200144, PubMed 36426942 -
T-helper cell regulation of CD45 phosphatase activity by galectin-1 and CD43 governs chronic lymphocytic leukaemia proliferation
Br J Haematol, 198 (3), 556-573
DOI 10.1111/bjh.18285, PubMed 35655388 -
Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer
Mol Ther Oncolytics, 26, 189-206
DOI 10.1016/j.omto.2022.06.007, PubMed 35860008 -
Impact of KIR-ligand mismatch on pediatric T-cell acute lymphoblastic leukemia in unrelated cord blood transplantation
Transplant Cell Ther, 28 (9), 598.e1-598.e8
DOI 10.1016/j.jtct.2022.05.037, PubMed 35660064 -
Strategies for Improving the Efficacy of CAR T Cells in Solid Cancers
Cancers (Basel), 14 (3)
DOI 10.3390/cancers14030571, PubMed 35158839 -
The Karolinska KI/K COVID-19 Immune Atlas: An open resource for immunological research and educational purposes
Scand J Immunol, 96 (1), e13195 (in press)
DOI 10.1111/sji.13195, PubMed 35652743 -
Piezo1 activation by stretching of uterine myometrium supports pregnancy and prevents preterm labour
J Physiol, 601 (4), 719-721
DOI 10.1113/JP283810, PubMed 36266732 -
HLA-independent T cell receptors for targeting tumors with low antigen density
Nat Med, 28 (2), 345-352
DOI 10.1038/s41591-021-01621-1, PubMed 35027758 -
Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction
J Infect Dis, 225 (4), 661-674
DOI 10.1093/infdis/jiaa714, PubMed 33216130 -
Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
J Acquir Immune Defic Syndr, 89 (1), 77-86
DOI 10.1097/QAI.0000000000002817, PubMed 34878437 -
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
Leukemia, 36 (7), 1887-1897
DOI 10.1038/s41375-022-01597-y, PubMed 35643867 -
Small Interfering RNA Delivery Into Primary Human Natural Killer Cells for Functional Gene Analyses
Curr Protoc, 2 (11), e613
DOI 10.1002/cpz1.613, PubMed 36440989 -
An optimized platform for efficient siRNA delivery into human NK cells
Eur J Immunol, 52 (7), 1190-1193
DOI 10.1002/eji.202149710, PubMed 35416292 -
Tryptophan depletion results in tryptophan-to-phenylalanine substitutants
Nature, 603 (7902), 721-727
DOI 10.1038/s41586-022-04499-2, PubMed 35264796 -
Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants
Nature, 608 (7922), E20
DOI 10.1038/s41586-022-05097-y, PubMed 35840685 -
Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination
Br J Haematol, 197 (6), 697-708
DOI 10.1111/bjh.18149, PubMed 35254660 -
Atezolizumab plus anthracycline-based chemotherapy in metastatic triple-negative breast cancer: the randomized, double-blind phase 2b ALICE trial
Nat Med, 28 (12), 2573-2583
DOI 10.1038/s41591-022-02126-1, PubMed 36482103 -
Improved survival after single-unit cord blood transplantation using fludarabine and melphalan-based reduced-intensity conditioning for malignant lymphoma: impact of melphalan dose and graft-versus-host disease prophylaxis with mycophenolate mofetil
Ann Hematol, 101 (12), 2743-2757
DOI 10.1007/s00277-022-04990-w, PubMed 36195679 -
NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer
Cancer Cell, 40 (9), 1027-1043.e9
DOI 10.1016/j.ccell.2022.08.005, PubMed 36099881 -
Expansion, persistence, and efficacy of donor memory-like NK cells infused for posttransplant relapse
J Clin Invest, 132 (11)
DOI 10.1172/JCI154334, PubMed 35349491 -
Functional testing of relapsed chronic lymphocytic leukemia guides precision medicine and maps response and resistance mechanisms. An index case
Haematologica, 107 (8), 1994-1998
DOI 10.3324/haematol.2021.280393, PubMed 35236056 -
Determining drug dose in the era of targeted therapies: playing it (un)safe?
Blood Cancer J, 12 (8), 123
DOI 10.1038/s41408-022-00720-7, PubMed 35999205 -
A national precision cancer medicine implementation initiative for Norway
Nat Med, 28 (5), 885-887
DOI 10.1038/s41591-022-01777-4, PubMed 35513529 -
Immunoregulatory signal networks and tumor immune evasion mechanisms: insights into therapeutic targets and agents in clinical development
Biochem J, 479 (20), 2219-2260
DOI 10.1042/BCJ20210233, PubMed 36305711 -
Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Clin Cancer Res, 28 (20), 4444-4455
DOI 10.1158/1078-0432.CCR-22-1221, PubMed 35998013 -
Improved outcomes of single-unit cord blood transplantation for acute myeloid leukemia by killer immunoglobulin-like receptor 2DL1-ligand mismatch
Bone Marrow Transplant, 57 (7), 1171-1179
DOI 10.1038/s41409-022-01700-y, PubMed 35538140 -
Structural Requirements for the Binding of a Peptide to Prohibitins on the Cell Surface of Monocytes/Macrophages
Int J Mol Sci, 23 (8)
DOI 10.3390/ijms23084282, PubMed 35457098 -
Health-related quality of life in patients with advanced melanoma treated with ipilimumab: prognostic implications and changes during treatment
ESMO Open, 7 (5), 100588
DOI 10.1016/j.esmoop.2022.100588, PubMed 36116420
Publications 2021
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T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
Nat Biotechnol, 40 (4), 488-498
DOI 10.1038/s41587-021-01089-x, PubMed 34873326 -
The Presence of Activated T Cell Subsets prior to Transplantation Is Associated with Increased Rejection Risk in Pancreas Transplant Recipients
J Immunol, 207 (10), 2501-2511
DOI 10.4049/jimmunol.2001103, PubMed 34607938 -
Proteomics of Mouse Heart Ventricles Reveals Mitochondria and Metabolism as Major Targets of a Post-Infarction Short-Acting GLP1Ra-Therapy
Int J Mol Sci, 22 (16)
DOI 10.3390/ijms22168711, PubMed 34445425 -
Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors
Oncoimmunology, 10 (1), 1936757
DOI 10.1080/2162402X.2021.1936757, PubMed 34235003 -
A simplified frailty score predicts survival and can aid treatment-intensity decisions in older patients with DLBCL
Blood Adv, 5 (22), 4771-4782
DOI 10.1182/bloodadvances.2021004777, PubMed 34543384 -
A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
Nat Commun, 12 (1), 6774
DOI 10.1038/s41467-021-27029-6, PubMed 34811370 -
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Sci Transl Med, 13 (582)
DOI 10.1126/scitranslmed.abb0036, PubMed 33627483 -
Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients
Front Cell Infect Microbiol, 11, 669623
DOI 10.3389/fcimb.2021.669623, PubMed 34307194 -
PRDX-1 Supports the Survival and Antitumor Activity of Primary and CAR-Modified NK Cells under Oxidative Stress
Cancer Immunol Res, 10 (2), 228-244
DOI 10.1158/2326-6066.CIR-20-1023, PubMed 34853030 -
Bioinformatic Analysis Reveals Central Role for Tumor-Infiltrating Immune Cells in Uveal Melanoma Progression
J Immunol Res, 2021, 9920234
DOI 10.1155/2021/9920234, PubMed 34195299 -
An extended APOBEC3A mutation signature in cancer
Nat Commun, 12 (1), 1602
DOI 10.1038/s41467-021-21891-0, PubMed 33707442 -
Systems approach reveals distinct and shared signaling networks of the four PGE2 receptors in T cells
Sci Signal, 14 (703), eabc8579
DOI 10.1126/scisignal.abc8579, PubMed 34609894 -
Phosphoproteomics-Based Characterization of Prostaglandin E2 Signaling in T Cells
Mol Pharmacol, 99 (5), 370-382
DOI 10.1124/molpharm.120.000170, PubMed 33674363 -
Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4+ T Cells in HIV-Infected Immunological Non-Responders
Front Immunol, 12, 744155
DOI 10.3389/fimmu.2021.744155, PubMed 34691047 -
Copy number signatures predict chromothripsis and clinical outcomes in newly diagnosed multiple myeloma
Nat Commun, 12 (1), 5172
DOI 10.1038/s41467-021-25469-8, PubMed 34453055 -
Chromothripsis as a pathogenic driver of multiple myeloma
Semin Cell Dev Biol, 123, 115-123
DOI 10.1016/j.semcdb.2021.04.014, PubMed 33958284 -
Advances in immune therapies in hematological malignancies
J Intern Med, 292 (2), 205-220
DOI 10.1111/joim.13395, PubMed 34624160 -
Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
Mol Oncol, 16 (5), 1153-1170
DOI 10.1002/1878-0261.13153, PubMed 34861096 -
"Built-in" PD-1 blocker to rescue NK-92 activity from PD-L1-mediated tumor escape mechanisms
FASEB J, 35 (9), e21750
DOI 10.1096/fj.202100025R, PubMed 34424568 -
Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo
MAbs, 13 (1), 1893888
DOI 10.1080/19420862.2021.1893888, PubMed 33691596 -
Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
Sci Rep, 11 (1), 6317
DOI 10.1038/s41598-021-85613-8, PubMed 33737576 -
Rapid genome editing by CRISPR-Cas9-POLD3 fusion
Elife, 10
DOI 10.7554/eLife.75415, PubMed 34898428 -
COVID-19 in patients with CLL: improved survival outcomes and update on management strategies
Blood, 138 (18), 1768-1773
DOI 10.1182/blood.2021011841, PubMed 34297826 -
mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies
Commun Biol, 4 (1), 424
DOI 10.1038/s42003-021-01938-0, PubMed 33782531 -
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
Mol Oncol, 16 (1), 88-103
DOI 10.1002/1878-0261.13047, PubMed 34165864 -
Outcome of allogeneic hematopoietic stem cell transplantation for follicular lymphoma relapsing after autologous transplantation: analysis of the Japan Society for Hematopoietic Cell Transplantation
Bone Marrow Transplant, 56 (6), 1462-1466
DOI 10.1038/s41409-020-01192-8, PubMed 33514920 -
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia
Cancer Res, 81 (22), 5733-5744
DOI 10.1158/0008-5472.CAN-21-0061, PubMed 34593524 -
RNA Interference: Story and Mechanisms
Methods Mol Biol, 2282, 1-15
DOI 10.1007/978-1-0716-1298-9_1, PubMed 33928566 -
Reducing the immunosuppressive tumor microenvironment enhances photoimmunotherapy efficacy
EBioMedicine, 67, 103351
DOI 10.1016/j.ebiom.2021.103351, PubMed 33965875 -
Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Cell Monolayer and Multicellular Tumor Spheroid Models
Cancers (Basel), 13 (13)
DOI 10.3390/cancers13133356, PubMed 34283089 -
Correction: Sioud et al. Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Monolayer and Multicellular Tumor Spheroid Models. Cancers 2021, 13, 3356
Cancers (Basel), 13 (21)
DOI 10.3390/cancers13215513, PubMed 34771754 -
Overcoming resistance to targeted therapies in chronic lymphocytic leukemia
Blood Adv, 5 (1), 334-343
DOI 10.1182/bloodadvances.2020003423, PubMed 33570649 -
What It Takes to Transform a T Cell
Cancer Res, 81 (12), 3160-3161
DOI 10.1158/0008-5472.CAN-21-0784, PubMed 34224376 -
The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma
Cancer Cell, 39 (10), 1422-1437.e10
DOI 10.1016/j.ccell.2021.08.011, PubMed 34597589 -
Natural killer cell receptors regulate responses of HLA-E-restricted T cells
Sci Immunol, 6 (58)
DOI 10.1126/sciimmunol.abe9057, PubMed 33893172 -
Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
Cell Stem Cell, 28 (12), 2062-2075.e5
DOI 10.1016/j.stem.2021.08.013, PubMed 34525347 -
Aspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial
Trials, 22 (1), 642
DOI 10.1186/s13063-021-05587-w, PubMed 34544470
Publications 2020
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A Systemic Protein Deviation Score Linked to PD-1+ CD8+ T Cell Expansion That Predicts Overall Survival in Diffuse Large B Cell Lymphoma
Med, 2 (2), 180-195.e5
DOI 10.1016/j.medj.2020.10.006, PubMed 35590201 -
Gene Editing in B-Lymphoma Cell Lines Using CRISPR/Cas9 Technology
Methods Mol Biol, 2115, 445-454
DOI 10.1007/978-1-0716-0290-4_25, PubMed 32006416 -
Anti-tumour immunity induces aberrant peptide presentation in melanoma
Nature, 590 (7845), 332-337
DOI 10.1038/s41586-020-03054-1, PubMed 33328638 -
CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile
Mucosal Immunol, 14 (2), 402-410
DOI 10.1038/s41385-020-0315-5, PubMed 32572129 -
Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
iScience, 23 (6), 101154
DOI 10.1016/j.isci.2020.101154, PubMed 32450518 -
Use of RNA Interference with TCR Transfer to Enhance Safety and Efficiency
Methods Mol Biol, 2115, 327-349
DOI 10.1007/978-1-0716-0290-4_18, PubMed 32006409 -
Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI
Aging (Albany NY), 12 (23), 23578-23597
DOI 10.18632/aging.202346, PubMed 33289702 -
DNMT3B deficiency alters mitochondrial biogenesis and α-ketoglutarate levels in human embryonic stem cells
Stem Cells, 38 (11), 1409-1422
DOI 10.1002/stem.3256, PubMed 32652733 -
TRP Channels as Interior Designers: Remodeling the Endolysosomal Compartment in Natural Killer Cells
Front Immunol, 11, 753
DOI 10.3389/fimmu.2020.00753, PubMed 32411146 -
Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis
Cancers (Basel), 12 (2)
DOI 10.3390/cancers12020377, PubMed 32041351 -
Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
Mol Ther, 29 (3), 1199-1213
DOI 10.1016/j.ymthe.2020.11.019, PubMed 33212301 -
Novel chimerized IgA CD20 antibodies: Improving neutrophil activation against CD20-positive malignancies
MAbs, 12 (1), 1795505
DOI 10.1080/19420862.2020.1795505, PubMed 32744145 -
Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency
Front Immunol, 11, 574738
DOI 10.3389/fimmu.2020.574738, PubMed 33193364 -
Umbilical Cord Blood and iPSC-Derived Natural Killer Cells Demonstrate Key Differences in Cytotoxic Activity and KIR Profiles
Front Immunol, 11, 561553
DOI 10.3389/fimmu.2020.561553, PubMed 33178188 -
The DLBCL90 gene-expression assay identifies double-hit lymphomas with high sensitivity in patients from two phase II clinical trials with high-risk diffuse large B-cell lymphoma
EJHaem, 2 (1), 104-108
DOI 10.1002/jha2.109, PubMed 35846101 -
Harnessing the Antiviral-Type Responses Induced by Immunostimulatory siRNAs for Cancer Immunotherapy
Methods Mol Biol, 2115, 281-287
DOI 10.1007/978-1-0716-0290-4_16, PubMed 32006407 -
The Oncometabolite 5'-Deoxy-5'-Methylthioadenosine Blocks Multiple Signaling Pathways of NK Cell Activation
Front Immunol, 11, 2128
DOI 10.3389/fimmu.2020.02128, PubMed 33123121 -
Minimal relapse risk and early normalization of survival for patients with Burkitt lymphoma treated with intensive immunochemotherapy: an international study of 264 real-world patients
Br J Haematol, 189 (4), 661-671
DOI 10.1111/bjh.16425, PubMed 32017050 -
Machine learning derived input-function in a dynamic 18F-FDG PET study of mice
Biomed Phys Eng Express, 6 (1), 015020
DOI 10.1088/2057-1976/ab6496, PubMed 33438608 -
ICON: a randomized phase IIb study evaluating immunogenic chemotherapy combined with ipilimumab and nivolumab in patients with metastatic hormone receptor positive breast cancer
J Transl Med, 18 (1), 269
DOI 10.1186/s12967-020-02421-w, PubMed 32620163 -
ALICE: a randomized placebo-controlled phase II study evaluating atezolizumab combined with immunogenic chemotherapy in patients with metastatic triple-negative breast cancer
J Transl Med, 18 (1), 252
DOI 10.1186/s12967-020-02424-7, PubMed 32576225 -
Combinatorial CAR design improves target restriction
J Biol Chem, 296, 100116
DOI 10.1074/jbc.RA120.016234, PubMed 33234592 -
Prospects for NK Cell Therapy of Sarcoma
Cancers (Basel), 12 (12)
DOI 10.3390/cancers12123719, PubMed 33322371 -
Tuning the Antigen Density Requirement for CAR T-cell Activity
Cancer Discov, 10 (5), 702-723
DOI 10.1158/2159-8290.CD-19-0945, PubMed 32193224 -
Outcomes of COVID-19 in patients with CLL: a multicenter international experience
Blood, 136 (10), 1134-1143
DOI 10.1182/blood.2020006965, PubMed 32688395 -
Natural killer cell immunotypes related to COVID-19 disease severity
Sci Immunol, 5 (50)
DOI 10.1126/sciimmunol.abd6832, PubMed 32826343 -
Correction to: Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
Cancer Immunol Immunother, 69 (1), 159-161
DOI 10.1007/s00262-019-02409-6, PubMed 31776597 -
Sensing of HIV-1 by TLR8 activates human T cells and reverses latency
Nat Commun, 11 (1), 147
DOI 10.1038/s41467-019-13837-4, PubMed 31919342 -
Exploring 5'-Biotinylation of the Sense Strand to Improve siRNA Specificity and Potency
Methods Mol Biol, 2115, 163-170
DOI 10.1007/978-1-0716-0290-4_9, PubMed 32006400 -
Preventing a shock to the system. Two-pore channel 1 negatively regulates anaphylaxis
Cell Calcium, 92, 102289
DOI 10.1016/j.ceca.2020.102289, PubMed 33027744 -
Deciphering Natural Killer Cell Homeostasis
Front Immunol, 11, 812
DOI 10.3389/fimmu.2020.00812, PubMed 32477340 -
Distribution of ACE2, CD147, CD26, and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors
Allergy, 75 (11), 2829-2845
DOI 10.1111/all.14429, PubMed 32496587 -
Cell Cycle Analysis and Relevance for Single-Cell Gating in Mass Cytometry
Cytometry A, 97 (8), 832-844
DOI 10.1002/cyto.a.23960, PubMed 31943748 -
RNA and CRISPR Interferences: Past, Present, and Future Perspectives
Methods Mol Biol, 2115, 1-22
DOI 10.1007/978-1-0716-0290-4_1, PubMed 32006392 -
Optimized siRNA Delivery into Primary Immune Cells Using Electroporation
Methods Mol Biol, 2115, 119-131
DOI 10.1007/978-1-0716-0290-4_7, PubMed 32006398 -
Unleashing the Therapeutic Potential of Dendritic and T Cell Therapies Using RNA Interference
Methods Mol Biol, 2115, 259-280
DOI 10.1007/978-1-0716-0290-4_15, PubMed 32006406 -
Microbial sensing by haematopoietic stem and progenitor cells: Vigilance against infections and immune education of myeloid cells
Scand J Immunol, 92 (5), e12957
DOI 10.1111/sji.12957, PubMed 32767789 -
B cell signalling pathways-New targets for precision medicine in chronic lymphocytic leukaemia
Scand J Immunol, 92 (5), e12931
DOI 10.1111/sji.12931, PubMed 32640099 -
Reduced polyfunctional T cells and increased cellular activation markers in adult allergy patients reporting adverse reactions to food
BMC Immunol, 21 (1), 43
DOI 10.1186/s12865-020-00373-w, PubMed 32698761 -
Improving Dendritic Cell Cancer Vaccine Potency Using RNA Interference
Methods Mol Biol, 2115, 249-258
DOI 10.1007/978-1-0716-0290-4_14, PubMed 32006405 -
Cellular immunotherapy with multiple infusions of in vitro-expanded haploidentical natural killer cells after autologous transplantation for patients with plasma cell myeloma
Cytotherapy, 23 (4), 329-338
DOI 10.1016/j.jcyt.2020.09.009, PubMed 33268029 -
Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
Blood Adv, 4 (9), 1859-1866
DOI 10.1182/bloodadvances.2019001325, PubMed 32374878 -
Next Generation of Adoptive T Cell Therapy Using CRISPR/Cas9 Technology: Universal or Boosted?
Methods Mol Biol, 2115, 407-417
DOI 10.1007/978-1-0716-0290-4_22, PubMed 32006413 -
Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity
Cell Stem Cell, 27 (2), 224-237.e6
DOI 10.1016/j.stem.2020.05.008, PubMed 32531207
Publications 2019
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Induction of neoantigen-reactive T cells from healthy donors
Nat Protoc, 14 (6), 1926-1943
DOI 10.1038/s41596-019-0170-6, PubMed 31101906 -
Resident memory CD8 T cells persist for years in human small intestine
J Exp Med, 216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737 -
EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
SLAS Discov, 24 (3), 398-413
DOI 10.1177/2472555218816276, PubMed 30616481 -
The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
J Immunol, 202 (5), 1397-1405
DOI 10.4049/jimmunol.1701703, PubMed 30692213 -
Imbalance of Genes Encoding Natural Killer Immunoglobulin-Like Receptors and Human Leukocyte Antigen in Patients With Biliary Cancer
Gastroenterology, 157 (4), 1067-1080.e9
DOI 10.1053/j.gastro.2019.06.023, PubMed 31229495 -
Hierarchical Normalized Completely Random Measures for Robust Graphical Modeling
Bayesian Anal, 14 (4), 1271-1301
DOI 10.1214/19-ba1153, PubMed 32431780 -
Correction: Ezrin-anchored PKA phosphorylates serine 369 and 373 on connexin 43 to enhance gap junction assembly, communication, and cell fusion
Biochem J, 476 (13), 1927
DOI 10.1042/BCJ-2017-0529_COR, PubMed 31266855 -
Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma
Front Immunol, 10, 2085
DOI 10.3389/fimmu.2019.02085, PubMed 31572357 -
Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency
J Allergy Clin Immunol Pract, 7 (6), 1970-1985.e4
DOI 10.1016/j.jaip.2019.02.038, PubMed 30877075 -
Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016
Lancet Neurol, 18 (5), 439-458
DOI 10.1016/S1474-4422(19)30034-1, PubMed 30871944 -
Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study
JAMA Oncol, 5 (12), 1749-1768
DOI 10.1001/jamaoncol.2019.2996, PubMed 31560378 -
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
Nat Commun, 10 (1), 514
DOI 10.1038/s41467-019-08384-x, PubMed 30705279 -
Expanding the Clinical Cytometry Toolbox-Receptor Occupancy by Mass Cytometry
Cytometry A, 95 (10), 1046-1048
DOI 10.1002/cyto.a.23784, PubMed 31046178 -
Human Germinal Center B Cells Differ from Naïve and Memory B Cells in CD40 Expression and CD40L-Induced Signaling Response
Cytometry A, 95 (4), 442-449
DOI 10.1002/cyto.a.23737, PubMed 30838773 -
TIGIT and PD-1 Mark Intratumoral T Cells with Reduced Effector Function in B-cell Non-Hodgkin Lymphoma
Cancer Immunol Res, 7 (3), 355-362
DOI 10.1158/2326-6066.CIR-18-0351, PubMed 30659053 -
Transient redirection of T cells for adoptive cell therapy with telomerase-specific T helper cell receptors isolated from long term survivors after cancer vaccination
Oncoimmunology, 8 (4), e1565236
DOI 10.1080/2162402X.2019.1565236, PubMed 30906659 -
Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma
Blood Adv, 3 (8), 1230-1243
DOI 10.1182/bloodadvances.2018029678, PubMed 30979721 -
NK cells specifically TCR-dressed to kill cancer cells
EBioMedicine, 40, 106-117
DOI 10.1016/j.ebiom.2019.01.031, PubMed 30665853 -
Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity
Oncoimmunology, 8 (3), 1558663
DOI 10.1080/2162402X.2018.1558663, PubMed 30723591 -
Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
Cancer Immunol Immunother, 68 (8), 1235-1243
DOI 10.1007/s00262-019-02356-2, PubMed 31214732 -
Finding Neo (antigens, that is)
Blood, 134 (2), 108-109
DOI 10.1182/blood.2019001334, PubMed 31296544 -
Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity
Cell Rep, 29 (8), 2284-2294.e4
DOI 10.1016/j.celrep.2019.10.058, PubMed 31747601 -
Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer
Oncogene, 38 (35), 6301-6318
DOI 10.1038/s41388-019-0879-2, PubMed 31312022 -
Releasing the Immune System Brakes Using siRNAs Enhances Cancer Immunotherapy
Cancers (Basel), 11 (2)
DOI 10.3390/cancers11020176, PubMed 30717461 -
Phage Display Libraries: From Binders to Targeted Drug Delivery and Human Therapeutics
Mol Biotechnol, 61 (4), 286-303
DOI 10.1007/s12033-019-00156-8, PubMed 30729435 -
Targeted Killing of Monocytes/Macrophages and Myeloid Leukemia Cells with Pro-Apoptotic Peptides
Cancers (Basel), 11 (8)
DOI 10.3390/cancers11081088, PubMed 31370273 -
Off-label uses of drugs for depression
Eur J Pharmacol, 865, 172732
DOI 10.1016/j.ejphar.2019.172732, PubMed 31622593 -
An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL
Leukemia, 34 (2), 478-487
DOI 10.1038/s41375-019-0569-7, PubMed 31471562 -
Carboxyl-Terminal Src Kinase Binds CD28 upon Activation and Mutes Downstream Signaling
J Immunol, 203 (4), 1055-1063
DOI 10.4049/jimmunol.1801660, PubMed 31292214 -
A clinico-molecular predictor identifies follicular lymphoma patients at risk of early transformation after first-line immunotherapy
Haematologica, 104 (10), e460-e464
DOI 10.3324/haematol.2018.209080, PubMed 30846496 -
Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery
AIDS, 33 (7), 1117-1129
DOI 10.1097/QAD.0000000000002173, PubMed 30789356 -
FOXK1 and FOXK2 regulate aerobic glycolysis
Nature, 566 (7743), 279-283
DOI 10.1038/s41586-019-0900-5, PubMed 30700909 -
An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
Nat Commun, 10 (1), 5499
DOI 10.1038/s41467-019-13329-5, PubMed 31796750 -
Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
NPJ Breast Cancer, 5, 13
DOI 10.1038/s41523-019-0108-8, PubMed 30993194 -
Huge whole-genome study of human metastatic cancers
Nature, 575 (7781), 60-61
DOI 10.1038/d41586-019-03123-0, PubMed 31690848
Publications 2018
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Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML
Clin Cancer Res, 24 (8), 1834-1844
DOI 10.1158/1078-0432.CCR-17-3196, PubMed 29444931 -
Innovative therapy, monoclonal antibodies, and beyond: Highlights from the eighth annual meeting
Cytokine Growth Factor Rev, 44, 1-10
DOI 10.1016/j.cytogfr.2018.10.005, PubMed 30393044 -
Serum cytokine profiles and metabolic tumor burden in patients with non-small cell lung cancer undergoing palliative thoracic radiation therapy
Adv Radiat Oncol, 3 (2), 130-138
DOI 10.1016/j.adro.2017.12.007, PubMed 29904737 -
Cryopreservation of primary B cells minimally influences their signaling responses
Sci Rep, 8 (1), 17651
DOI 10.1038/s41598-018-36121-9, PubMed 30518828 -
The MCL35 gene expression proliferation assay predicts high-risk MCL patients in a Norwegian cohort of younger patients given intensive first line therapy
Br J Haematol, 183 (2), 225-234
DOI 10.1111/bjh.15518, PubMed 30080252 -
Induction of the BIM Short Splice Variant Sensitizes Proliferating NK Cells to IL-15 Withdrawal
J Immunol, 202 (3), 736-746
DOI 10.4049/jimmunol.1801146, PubMed 30578306 -
Prevalence and clinical challenges among adults with primary immunodeficiency and recombination-activating gene deficiency
J Allergy Clin Immunol, 141 (6), 2303-2306
DOI 10.1016/j.jaci.2018.02.007, PubMed 29477728 -
Molecular classification of primary mediastinal large B-cell lymphoma using routinely available tissue specimens
Blood, 132 (22), 2401-2405
DOI 10.1182/blood-2018-05-851154, PubMed 30257882 -
Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors
Cancer Immunol Res, 6 (4), 467-480
DOI 10.1158/2326-6066.CIR-17-0207, PubMed 29459477 -
Epidermal growth factor receptor (EGFR) density may not be the only determinant for the efficacy of EGFR-targeted photoimmunotherapy in human head and neck cancer cell lines
Lasers Surg Med, 50 (5), 513-522
DOI 10.1002/lsm.22930, PubMed 29777587 -
OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells
Mol Biol Cell, 29 (12), 1487-1501
DOI 10.1091/mbc.E17-09-0538, PubMed 29688805 -
Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells
Semin Immunopathol, 41 (1), 59-68
DOI 10.1007/s00281-018-0721-x, PubMed 30361801 -
Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects
J Allergy Clin Immunol, 142 (6), 1932-1946
DOI 10.1016/j.jaci.2018.02.055, PubMed 29729943 -
T-cell cross-reactivity may explain the large variation in how cancer patients respond to checkpoint inhibitors
Scand J Immunol, 87 (3)
DOI 10.1111/sji.12643, PubMed 29381830 -
Development of a new high-affinity human antibody with antitumor activity against solid and blood malignancies
FASEB J, 32 (9), 5063-5077
DOI 10.1096/fj.201701544R, PubMed 29913558 -
Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry
Am J Pathol, 188 (7), 1563-1579
DOI 10.1016/j.ajpath.2018.03.017, PubMed 29684362 -
Sample-Index Misassignment Impacts Tumour Exome Sequencing
Sci Rep, 8 (1), 5307
DOI 10.1038/s41598-018-23563-4, PubMed 29593270 -
Artesunate shows potent anti-tumor activity in B-cell lymphoma
J Hematol Oncol, 11 (1), 23
DOI 10.1186/s13045-018-0561-0, PubMed 29458389
Publications 2017
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BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5
PLoS One, 12 (5), e0177188
DOI 10.1371/journal.pone.0177188, PubMed 28489883 -
Bioinformatics Approaches to Profile the Tumor Microenvironment for Immunotherapeutic Discovery
Curr Pharm Des, 23 (32), 4716-4725
DOI 10.2174/1381612823666170710154936, PubMed 28699527 -
Human c-SRC kinase (CSK) overexpression makes T cells dummy
Cancer Immunol Immunother, 67 (4), 525-536
DOI 10.1007/s00262-017-2105-9, PubMed 29248956 -
T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth
Oncoimmunology, 6 (4), e1302631
DOI 10.1080/2162402X.2017.1302631, PubMed 28507809 -
Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
Sci Rep, 7 (1), 4916
DOI 10.1038/s41598-017-04982-1, PubMed 28687807 -
T Cells Expressing Checkpoint Receptor TIGIT Are Enriched in Follicular Lymphoma Tumors and Characterized by Reversible Suppression of T-cell Receptor Signaling
Clin Cancer Res, 24 (4), 870-881
DOI 10.1158/1078-0432.CCR-17-2337, PubMed 29217528 -
The Potential of Donor T-Cell Repertoires in Neoantigen-Targeted Cancer Immunotherapy
Front Immunol, 8, 1718
DOI 10.3389/fimmu.2017.01718, PubMed 29321773 -
Fishing therapeutic T-cell receptors in healthy donor blood, is safety predictable?
Transl. Cancer Res., 6 3, S622-S624
DOI 10.21037/tcr.2017.05.25 -
Phase I/IIa clinical trial of a novel hTERT peptide vaccine in men with metastatic hormone-naive prostate cancer
Cancer Immunol Immunother, 66 (7), 891-901
DOI 10.1007/s00262-017-1994-y, PubMed 28391357 -
Ex Vivo Expanded Adaptive NK Cells Effectively Kill Primary Acute Lymphoblastic Leukemia Cells
Cancer Immunol Res, 5 (8), 654-665
DOI 10.1158/2326-6066.CIR-16-0296, PubMed 28637877 -
Natural killer cell-mediated immunosurveillance of human cancer
Semin Immunol, 31, 20-29
DOI 10.1016/j.smim.2017.08.002, PubMed 28888619 -
Immune selection during tumor checkpoint inhibition therapy paves way for NK-cell "missing self" recognition
Immunogenetics, 69 (8-9), 547-556
DOI 10.1007/s00251-017-1011-9, PubMed 28699110 -
Manufacture of CAR-T cells in the body
Nat Biotechnol, 35 (6), 520-521
DOI 10.1038/nbt.3898, PubMed 28591119 -
Disease evolution in mixed connective tissue disease: results from a long-term nationwide prospective cohort study
Arthritis Res Ther, 19 (1), 284
DOI 10.1186/s13075-017-1494-7, PubMed 29268795 -
New Molecular Assay for the Proliferation Signature in Mantle Cell Lymphoma Applicable to Formalin-Fixed Paraffin-Embedded Biopsies
J Clin Oncol, 35 (15), 1668-1677
DOI 10.1200/JCO.2016.70.7901, PubMed 28291392 -
Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia
Sci Rep, 7, 39710
DOI 10.1038/srep39710, PubMed 28054583 -
Defective IL-4 signaling in T cells defines severe common variable immunodeficiency
J Autoimmun, 81, 110-119
DOI 10.1016/j.jaut.2017.04.004, PubMed 28476239 -
CD56bright NK cells exhibit potent antitumor responses following IL-15 priming
J Clin Invest, 127 (11), 4042-4058
DOI 10.1172/JCI90387, PubMed 28972539 -
A TCR-based Chimeric Antigen Receptor
Sci Rep, 7 (1), 10713
DOI 10.1038/s41598-017-11126-y, PubMed 28878363 -
Mass Cytometry of Follicular Lymphoma Tumors Reveals Intrinsic Heterogeneity in Proteins Including HLA-DR and a Deficit in Nonmalignant Plasmablast and Germinal Center B-Cell Populations
Cytometry B Clin Cytom, 92 (1), 79-87
DOI 10.1002/cyto.b.21498, PubMed 27933753
Publications 2016
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Deep Sequencing Analysis of Nucleolar Small RNAs: RNA Isolation and Library Preparation
Methods Mol Biol, 1455, 231-41
DOI 10.1007/978-1-4939-3792-9_18, PubMed 27576723 -
Deep Sequencing Analysis of Nucleolar Small RNAs: Bioinformatics
Methods Mol Biol, 1455, 243-8
DOI 10.1007/978-1-4939-3792-9_19, PubMed 27576724 -
Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants
Mol Ther, 24 (9), 1675-85
DOI 10.1038/mt.2016.134, PubMed 27377043 -
Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
J Immunol, 196 (3), 1400-11
DOI 10.4049/jimmunol.1501434, PubMed 26746188 -
The tumour microenvironment influences survival and time to transformation in follicular lymphoma in the rituximab era
Br J Haematol, 175 (1), 102-14
DOI 10.1111/bjh.14201, PubMed 27341313 -
Cancer immunotherapy: from the lab to clinical applications-Potential impact on cancer centres' organisation
Ecancermedicalscience, 10, 691
DOI 10.3332/ecancer.2016.691, PubMed 27994647 -
Profiling networks of distinct immune-cells in tumors
BMC Bioinformatics, 17 (1), 263
DOI 10.1186/s12859-016-1141-3, PubMed 27377892 -
Erratum: Individualized strategies to target specific mechanisms of disease in malignant melanoma patients displaying unique mutational signatures
Oncotarget, 7 (5), 6352
DOI 10.18632/oncotarget.7118, PubMed 26997263 -
Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease
Clin Transl Immunology, 5 (11), e109
DOI 10.1038/cti.2016.65, PubMed 27990285 -
Suppressive effects of tumor cell-derived 5'-deoxy-5'-methylthioadenosine on human T cells
Oncoimmunology, 5 (8), e1184802
DOI 10.1080/2162402X.2016.1184802, PubMed 27622058 -
Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease
J Hepatol, 66 (1), 116-122
DOI 10.1016/j.jhep.2016.09.002, PubMed 27647428 -
Myeloid cell leukaemia 1 has a vital role in retinoic acid-mediated protection of Toll-like receptor 9-stimulated B cells from spontaneous and DNA damage-induced apoptosis
Immunology, 149 (1), 62-73
DOI 10.1111/imm.12629, PubMed 27278254 -
Class I HLA haplotypes form two schools that educate NK cells in different ways
Sci Immunol, 1 (3)
DOI 10.1126/sciimmunol.aag1672, PubMed 27868107 -
T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy
Oncoimmunology, 5 (12), e1249090
DOI 10.1080/2162402X.2016.1249090, PubMed 28123886 -
Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells
Oncoimmunology, 5 (11), e1232237
DOI 10.1080/2162402X.2016.1232237, PubMed 27999747 -
Cognate HLA absence in trans diminishes human NK cell education
J Clin Invest, 126 (10), 3772-3782
DOI 10.1172/JCI86923, PubMed 27571408 -
Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans
Cell Rep, 15 (5), 1088-1099
DOI 10.1016/j.celrep.2016.04.005, PubMed 27117418 -
Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA
Oncoimmunology, 5 (5), e1138199
DOI 10.1080/2162402X.2016.1138199, PubMed 27467957 -
Cancer cell-binding peptide fused Fc domain activates immune effector cells and blocks tumor growth
Oncotarget, 7 (46), 75940-75953
DOI 10.18632/oncotarget.12445, PubMed 27713158 -
Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling
Blood, 129 (6), 759-770
DOI 10.1182/blood-2016-05-718494, PubMed 28011673 -
Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine
Case Rep Med, 2016, 9639585
DOI 10.1155/2016/9639585, PubMed 27504122 -
Targeting of cancer neoantigens with donor-derived T cell receptor repertoires
Science, 352 (6291), 1337-41
DOI 10.1126/science.aaf2288, PubMed 27198675 -
Patterns of constitutively phosphorylated kinases in B cells are associated with disease severity in common variable immunodeficiency
Clin Immunol, 175, 69-74
DOI 10.1016/j.clim.2016.11.014, PubMed 27919819 -
Flow Cytometry-based Assay for the Monitoring of NK Cell Functions
J Vis Exp (116)
DOI 10.3791/54615, PubMed 27842341 -
VOLIN and KJON-Two novel hyperdiploid myeloma cell lines
Genes Chromosomes Cancer, 55 (11), 890-901
DOI 10.1002/gcc.22388, PubMed 27311012 -
Mechanism-Based Strategies for the Management of Autoimmunity and Immune Dysregulation in Primary Immunodeficiencies
J Allergy Clin Immunol Pract, 4 (6), 1089-1100
DOI 10.1016/j.jaip.2016.08.004, PubMed 27836058 -
PI3-kinase mutation linked to insulin and growth factor resistance in vivo
J Clin Invest, 126 (4), 1401-12
DOI 10.1172/JCI84005, PubMed 26974159 -
Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic Latency
Cancer Res, 76 (15), 4347-58
DOI 10.1158/0008-5472.CAN-16-0008, PubMed 27261508 -
Frizzled2 signaling regulates growth of high-risk neuroblastomas by interfering with β-catenin-dependent and β-catenin-independent signaling pathways
Oncotarget, 7 (29), 46187-46202
DOI 10.18632/oncotarget.10070, PubMed 27323822
Publications 2015
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Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model
Gene Ther, 22 (5), 391-403
DOI 10.1038/gt.2015.4, PubMed 25652098 -
Polyclonal Expansion of NKG2C(+) NK Cells in TAP-Deficient Patients
Front Immunol, 6, 507
DOI 10.3389/fimmu.2015.00507, PubMed 26500647 -
Computerized image analysis of the Ki-67 proliferation index in mantle cell lymphoma
Histopathology, 67 (1), 62-9
DOI 10.1111/his.12624, PubMed 25431344 -
Content of endothelial progenitor cells in autologous stem cell grafts predict survival after transplantation for multiple myeloma
Biol Blood Marrow Transplant, 21 (5), 840-7
DOI 10.1016/j.bbmt.2014.12.027, PubMed 25689789 -
New distinct compartments in the G2 phase of the cell cycle defined by the levels of γH2AX
Cell Cycle, 14 (20), 3261-9
DOI 10.1080/15384101.2015.1087617, PubMed 26317799 -
Coordinated expression of DNAM-1 and LFA-1 in educated NK cells
J Immunol, 194 (9), 4518-27
DOI 10.4049/jimmunol.1401972, PubMed 25825444 -
Microchip-Based Single-Cell Imaging Reveals That CD56dimCD57-KIR-NKG2A+ NK Cells Have More Dynamic Migration Associated with Increased Target Cell Conjugation and Probability of Killing Compared to CD56dimCD57-KIR-NKG2A- NK Cells
J Immunol, 195 (7), 3374-81
DOI 10.4049/jimmunol.1500171, PubMed 26320254 -
Newtonian cell interactions shape natural killer cell education
Immunol Rev, 267 (1), 197-213
DOI 10.1111/imr.12325, PubMed 26284479 -
Immunological factors influencing clinical outcome in lung cancer patients after telomerase peptide vaccination
Cancer Immunol Immunother, 64 (12), 1609-21
DOI 10.1007/s00262-015-1766-5, PubMed 26498005 -
Engineering therapeutic cancer vaccines that activate antitumor immunity
Methods Mol Biol, 1218, 263-8
DOI 10.1007/978-1-4939-1538-5_15, PubMed 25319656 -
NK Cell Subgroups, Phenotype, and Functions After Autologous Stem Cell Transplantation
Front Immunol, 6, 583
DOI 10.3389/fimmu.2015.00583, PubMed 26635797 -
T-cell receptor gene therapy--ready to go viral?
Mol Oncol, 9 (10), 2019-42
DOI 10.1016/j.molonc.2015.10.006, PubMed 26548533 -
"In situ" vaccination for systemic effects in follicular lymphoma
Oncoimmunology, 4 (7), e1014773
DOI 10.1080/2162402X.2015.1014773, PubMed 26140239 -
High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires
Hepatology, 63 (5), 1608-19
DOI 10.1002/hep.28116, PubMed 26257205 -
Harnessing adaptive natural killer cells in cancer immunotherapy
Mol Oncol, 9 (10), 1904-17
DOI 10.1016/j.molonc.2015.10.001, PubMed 26604011 -
A facile method for interfering with off-target silencing mediated by the sense strand
Methods Mol Biol, 1218, 293-300
DOI 10.1007/978-1-4939-1538-5_18, PubMed 25319659 -
Recombinant Lactobacillus plantarum induces immune responses to cancer testis antigen NY-ESO-1 and maturation of dendritic cells
Hum Vaccin Immunother, 11 (11), 2664-73
DOI 10.1080/21645515.2015.1056952, PubMed 26185907 -
Incidence of Data Duplications in a Randomly Selected Pool of Life Science Publications
Sci Eng Ethics, 22 (2), 487-96
DOI 10.1007/s11948-015-9668-7, PubMed 26065681 -
The targeting of human and mouse B lymphocytes by dasatinib
Exp Hematol, 43 (5), 352-363.e4
DOI 10.1016/j.exphem.2015.01.008, PubMed 25641047 -
Magnetic bead-based isolation of exosomes
Methods Mol Biol, 1218, 465-81
DOI 10.1007/978-1-4939-1538-5_27, PubMed 25319668 -
Cancer immunotherapy--Converting immune failure to clinical response
Mol Oncol, 9 (10), 1891-3
DOI 10.1016/j.molonc.2015.10.017, PubMed 26563645 -
Cutting Edge: Redox Signaling Hypersensitivity Distinguishes Human Germinal Center B Cells
J Immunol, 195 (4), 1364-1367
DOI 10.4049/jimmunol.1500904, PubMed 26157177 -
Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function
Immunity, 42 (3), 443-56
DOI 10.1016/j.immuni.2015.02.008, PubMed 25786176 -
RNA interference: mechanisms, technical challenges, and therapeutic opportunities
Methods Mol Biol, 1218, 1-15
DOI 10.1007/978-1-4939-1538-5_1, PubMed 25319642 -
Cytoplasmic delivery of siRNAs to monocytes and dendritic cells via electroporation
Methods Mol Biol, 1218, 107-15
DOI 10.1007/978-1-4939-1538-5_6, PubMed 25319647 -
Strategies for siRNA navigation to desired cells
Methods Mol Biol, 1218, 201-16
DOI 10.1007/978-1-4939-1538-5_12, PubMed 25319653 -
Overcoming the challenges of siRNA activation of innate immunity: design better therapeutic siRNAs
Methods Mol Biol, 1218, 301-19
DOI 10.1007/978-1-4939-1538-5_19, PubMed 25319660 -
Modified 2'-ribose small RNAs function as Toll-like receptor-7/8 antagonists
Methods Mol Biol, 1218, 483-9
DOI 10.1007/978-1-4939-1538-5_28, PubMed 25319669 -
Immunosuppressive factor blockade in dendritic cells via siRNAs results in objective clinical responses
Methods Mol Biol, 1218, 269-76
DOI 10.1007/978-1-4939-1538-5_16, PubMed 25319657 -
Generation of new peptide-Fc fusion proteins that mediate antibody-dependent cellular cytotoxicity against different types of cancer cells
Mol Ther Methods Clin Dev, 2, 15043
DOI 10.1038/mtm.2015.43, PubMed 26605373 -
Impact of KIR and HLA Genotypes on Outcomes after Reduced-Intensity Conditioning Hematopoietic Cell Transplantation
Biol Blood Marrow Transplant, 21 (9), 1589-96
DOI 10.1016/j.bbmt.2015.05.002, PubMed 25960307 -
Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome
Oncotarget, 6 (33), 34178-90
DOI 10.18632/oncotarget.6213, PubMed 26497557 -
Unpredicted phenotypes of two mutants of the TcR DMF5
J Immunol Methods, 425, 37-44
DOI 10.1016/j.jim.2015.06.006, PubMed 26079729 -
Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
ACS Chem Biol, 11 (1), 251-62
DOI 10.1021/acschembio.5b00734, PubMed 26569462 -
Increased incidence of chronic GvHD and CMV disease in patients with vitamin D deficiency before allogeneic stem cell transplantation
Bone Marrow Transplant, 50 (9), 1217-23
DOI 10.1038/bmt.2015.123, PubMed 26030049 -
Soluble T-cell receptors produced in human cells for targeted delivery
PLoS One, 10 (4), e0119559
DOI 10.1371/journal.pone.0119559, PubMed 25875651 -
Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy
Methods Mol Biol, 1218, 143-61
DOI 10.1007/978-1-4939-1538-5_9, PubMed 25319650
Publications 2014
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Role for early-differentiated natural killer cells in infectious mononucleosis
Blood, 124 (16), 2533-43
DOI 10.1182/blood-2014-01-553024, PubMed 25205117 -
A gene panel, including LRP12, is frequently hypermethylated in major types of B-cell lymphoma
PLoS One, 9 (9), e104249
DOI 10.1371/journal.pone.0104249, PubMed 25226156 -
Tracing dynamic expansion of human NK-cell subsets by high-resolution analysis of KIR repertoires and cellular differentiation
Eur J Immunol, 44 (7), 2192-6
DOI 10.1002/eji.201444464, PubMed 24723455 -
High dose chemotherapy with autologous stem cell transplant for patients with transformed B-cell non-Hodgkin lymphoma in the rituximab era
Leuk Lymphoma, 55 (10), 2319-27
DOI 10.3109/10428194.2013.871632, PubMed 24432894 -
Combining MYC, BCL2 and TP53 gene and protein expression alterations improves risk stratification in diffuse large B-cell lymphoma
Leuk Lymphoma, 56 (6), 1742-9
DOI 10.3109/10428194.2014.970550, PubMed 25284491 -
Low incidence of hyperfibrinolysis and thromboembolism in 195 primary liver transplantations transfused with solvent/detergent-treated plasma
Clin Med Res, 12 (1-2), 27-32
DOI 10.3121/cmr.2013.1168, PubMed 24415744 -
Sequential intranodal immunotherapy induces antitumor immunity and correlated regression of disseminated follicular lymphoma
Blood, 125 (1), 82-9
DOI 10.1182/blood-2014-07-592162, PubMed 25293773 -
High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8+ T cells
Eur J Immunol, 44 (11), 3439-52
DOI 10.1002/eji.201444662, PubMed 25103993 -
Effects of HDV infection and pegylated interferon α treatment on the natural killer cell compartment in chronically infected individuals
Gut, 64 (3), 469-82
DOI 10.1136/gutjnl-2014-306767, PubMed 24721903 -
Therapeutic vaccines for cancer: an overview of clinical trials
Nat Rev Clin Oncol, 11 (9), 509-24
DOI 10.1038/nrclinonc.2014.111, PubMed 25001465 -
Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease
Blood, 124 (5), 812-21
DOI 10.1182/blood-2013-11-536888, PubMed 24855210 -
Expression of B-cell surface antigens in subpopulations of exosomes released from B-cell lymphoma cells
Clin Ther, 36 (6), 847-862.e1
DOI 10.1016/j.clinthera.2014.05.010, PubMed 24952935 -
Prognostic influence of macrophages in patients with diffuse large B-cell lymphoma: a correlative study from a Nordic phase II trial
Haematologica, 100 (2), 238-45
DOI 10.3324/haematol.2014.113472, PubMed 25381134 -
Determining cell-of-origin subtypes of diffuse large B-cell lymphoma using gene expression in formalin-fixed paraffin-embedded tissue
Blood, 123 (8), 1214-7
DOI 10.1182/blood-2013-11-536433, PubMed 24398326 -
Engineering better immunotherapies via RNA interference
Hum Vaccin Immunother, 10 (11), 3165-74
DOI 10.4161/hv.29754, PubMed 25483669 -
Common variable immunodeficiency revisited: normal generation of naturally occurring dendritic cells that respond to Toll-like receptors 7 and 9
Clin Exp Immunol, 175 (3), 439-48
DOI 10.1111/cei.12239, PubMed 24237110 -
Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms
Cancer Discov, 4 (4), 480-93
DOI 10.1158/2159-8290.CD-13-0915, PubMed 24491438
Publications 2013
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Signaling pathways in lymphoma: pathogenesis and therapeutic targets
Future Oncol, 9 (10), 1549-71
DOI 10.2217/fon.13.113, PubMed 24106904 -
Independent skewing of the T cell and NK cell compartments associated with cytomegalovirus infection suggests division of labor between innate and adaptive immunity
Age (Dordr), 36 (2), 571-82
DOI 10.1007/s11357-013-9587-y, PubMed 24065293 -
Identification of highly methylated genes across various types of B-cell non-hodgkin lymphoma
PLoS One, 8 (11), e79602
DOI 10.1371/journal.pone.0079602, PubMed 24260260 -
Colorectal cancer DNA methylation marker panel validated with high performance in Non-Hodgkin lymphoma
Epigenetics, 9 (3), 428-36
DOI 10.4161/epi.27554, PubMed 24362313 -
NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs
Blood, 121 (14), 2678-88
DOI 10.1182/blood-2012-10-459545, PubMed 23325834 -
Influence of KIR gene copy number on natural killer cell education
Blood, 121 (23), 4703-7
DOI 10.1182/blood-2012-10-461442, PubMed 23637128 -
Whole-genome integrative analysis reveals expression signatures predicting transformation in follicular lymphoma
Blood, 123 (7), 1051-4
DOI 10.1182/blood-2013-07-512392, PubMed 24357726 -
EZH2 mutations are frequent and represent an early event in follicular lymphoma
Blood, 122 (18), 3165-8
DOI 10.1182/blood-2013-04-496893, PubMed 24052547 -
Immune escape of cancer cells with beta2-microglobulin loss over the course of metastatic melanoma
Int J Cancer, 134 (1), 102-13
DOI 10.1002/ijc.28338, PubMed 23784959 -
Non-allergic, mastocytosis-associated rhinitis
Clin Exp Allergy, 43 (4), 406-12
DOI 10.1111/cea.12053, PubMed 23517036 -
Karyotyping of diffuse large B-cell lymphomas: loss of 17p is associated with poor patient outcome
Eur J Haematol, 91 (4), 332-8
DOI 10.1111/ejh.12171, PubMed 23859481 -
Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes
Proc Natl Acad Sci U S A, 111 (1), 403-8
DOI 10.1073/pnas.1306549111, PubMed 24344295 -
[The cancer riddle is outdated]
Tidsskr Nor Laegeforen, 133 (18), 1907
DOI 10.4045/tidsskr.13.1037, PubMed 24084948 -
Exosome-derived miRNAs and cellular miRNAs activate innate immunity
J Innate Immun, 6 (1), 105-10
DOI 10.1159/000351460, PubMed 23774807 -
High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells
Blood, 121 (8), 1367-76
DOI 10.1182/blood-2012-04-421826, PubMed 23297127 -
Lamin A/C cleavage by caspase-6 activation is crucial for apoptotic induction by photodynamic therapy with hexaminolevulinate in human B-cell lymphoma cells
Cancer Lett, 339 (1), 25-32
DOI 10.1016/j.canlet.2013.07.026, PubMed 23916608 -
Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients
Int J Oncol, 43 (1), 280-8
DOI 10.3892/ijo.2013.1922, PubMed 23620105 -
A novel peptide carrier for efficient targeting of antigens and nucleic acids to dendritic cells
FASEB J, 27 (8), 3272-83
DOI 10.1096/fj.12-224758, PubMed 23671272 -
Natural killer cell inhibitory receptor expression in humans and mice: a closer look
Front Immunol, 4, 65
DOI 10.3389/fimmu.2013.00065, PubMed 23532016 -
Classification of human natural killer cells based on migration behavior and cytotoxic response
Blood, 121 (8), 1326-34
DOI 10.1182/blood-2012-06-439851, PubMed 23287857 -
Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma
Cancer Immunol Immunother, 62 (9), 1499-509
DOI 10.1007/s00262-013-1453-3, PubMed 23817721 -
Higher World Health Organization grades of follicular lymphoma correlate with better outcome in two Nordic Lymphoma Group trials of rituximab without chemotherapy
Leuk Lymphoma, 55 (2), 288-95
DOI 10.3109/10428194.2013.802778, PubMed 23662992 -
Identification and characterization of cells with cancer stem cell properties in human primary lung cancer cell lines
PLoS One, 8 (3), e57020 (Retracted)
DOI 10.1371/journal.pone.0057020, PubMed 23469181 -
In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines
Exp Hematol Oncol, 2 (1), 16
DOI 10.1186/2162-3619-2-16, PubMed 23738757 -
Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation
Eur J Immunol, 44 (3), 774-84
DOI 10.1002/eji.201343671, PubMed 24293164 -
Influence of polymorphisms in genes encoding immunoregulatory proteins and metabolizing enzymes on susceptibility and outcome in patients with diffuse large B-cell lymphoma treated with rituximab
Leuk Lymphoma, 54 (10), 2205-14
DOI 10.3109/10428194.2013.774392, PubMed 23391141 -
Inhibition of stromal PlGF suppresses the growth of prostate cancer xenografts
Int J Mol Sci, 14 (9), 17958-71
DOI 10.3390/ijms140917958, PubMed 24005860
Publications 2012
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SARA is dispensable for functional TGF-β signaling
FEBS Lett, 586 (19), 3367-72
DOI 10.1016/j.febslet.2012.07.027, PubMed 22819827 -
Interferon regulatory factor-8 is important for histone deacetylase inhibitor-mediated antitumor activity
PLoS One, 7 (9), e45422
DOI 10.1371/journal.pone.0045422, PubMed 23028998 -
CD8 T cells express randomly selected KIRs with distinct specificities compared with NK cells
Blood, 120 (17), 3455-65
DOI 10.1182/blood-2012-03-416867, PubMed 22968455 -
Phospho-specific flow cytometry identifies aberrant signaling in indolent B-cell lymphoma
BMC Cancer, 12, 478
DOI 10.1186/1471-2407-12-478, PubMed 23072591 -
Altered BCR and CD40 signalling are associated with clinical outcome in small lymphocytic lymphoma/chronic lymphocytic leukaemia and marginal zone lymphoma patients
Br J Haematol, 159 (5), 604-8
DOI 10.1111/bjh.12073, PubMed 23043253 -
Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma
PLoS One, 7 (10), e46117
DOI 10.1371/journal.pone.0046117, PubMed 23049692 -
Widespread CD4+ T-cell reactivity to novel hTERT epitopes following vaccination of cancer patients with a single hTERT peptide GV1001
Oncoimmunology, 1 (5), 670-686
DOI 10.4161/onci.20426, PubMed 22934259 -
Leishmania donovani: immunostimulatory cellular responses of membrane and soluble protein fractions of splenic amastigotes in cured patient and hamsters
PLoS One, 7 (1), e30746
DOI 10.1371/journal.pone.0030746, PubMed 22292030 -
Toward a prime-boost regime for NK cells?
Blood, 120 (24), 4663-4
DOI 10.1182/blood-2012-09-457184, PubMed 23223209 -
Spotlight on NKG2C and the human NK-cell response to CMV infection
Eur J Immunol, 42 (12), 3141-5
DOI 10.1002/eji.201243050, PubMed 23255011 -
Copynumber: Efficient algorithms for single- and multi-track copy number segmentation
BMC Genomics, 13, 591
DOI 10.1186/1471-2164-13-591, PubMed 23442169 -
Effect of cycloheximide on epidermal growth factor receptor trafficking and signaling
FEBS Lett, 586 (20), 3575-81
DOI 10.1016/j.febslet.2012.08.022, PubMed 22971756 -
[Can the immune system target cancer?]
Tidsskr Nor Laegeforen, 132 (7), 784-5
DOI 10.4045/tidsskr.12.0156, PubMed 22511078 -
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
Nature, 490 (7418), 116-20
DOI 10.1038/nature11378, PubMed 22885699 -
Efficient siRNA targeted delivery into cancer cells by gastrin-releasing peptides
Bioconjug Chem, 23 (5), 1040-9
DOI 10.1021/bc300050j, PubMed 22443209 -
Selective killing of cancer cells by peptide-targeted delivery of an anti-microbial peptide
Biochem Pharmacol, 84 (9), 1123-32
DOI 10.1016/j.bcp.2012.08.002, PubMed 22922046 -
Polymorphisms in genes encoding interleukin-10 and drug metabolizing enzymes GSTP1, GSTT1, GSTA1 and UGT1A1 influence risk and outcome in Hodgkin lymphoma
Leuk Lymphoma, 53 (10), 1934-44
DOI 10.3109/10428194.2012.682307, PubMed 22475179 -
Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnα1 and Kpnβ1
Traffic, 13 (5), 650-64
DOI 10.1111/j.1600-0854.2012.01341.x, PubMed 22321063
Publications 2011
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T cells raised against allogeneic HLA-A2/CD20 kill primary follicular lymphoma and acute lymphoblastic leukemia cells
Int J Cancer, 130 (8), 1821-32
DOI 10.1002/ijc.26209, PubMed 21630262 -
Polyelectrolyte multilayer capsules with quantum dots for biomedical applications
Colloids Surf B Biointerfaces, 90, 211-6
DOI 10.1016/j.colsurfb.2011.10.028, PubMed 22078925 -
Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment
Blood, 118 (5), 1350-8
DOI 10.1182/blood-2011-03-345272, PubMed 21670469 -
Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial
Clin Cancer Res, 17 (21), 6847-57
DOI 10.1158/1078-0432.CCR-11-1385, PubMed 21918169 -
Is secretion of tumour-specific antigen important for cancer eradication by CD4(+) T cells?--Implications for cancer immunotherapy by adoptive T cell transfer
Scand J Immunol, 73 (6), 527-30
DOI 10.1111/j.1365-3083.2011.02558.x, PubMed 21388431 -
High dose chemotherapy with autologous stem cell support for patients with histologically transformed B-cell non-Hodgkin lymphomas. A Norwegian multi centre phase II study
Br J Haematol, 152 (5), 600-10
DOI 10.1111/j.1365-2141.2010.08519.x, PubMed 21241276 -
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC
Leukemia, 26 (5), 1073-80
DOI 10.1038/leu.2011.263, PubMed 21941367 -
Vaccination of patients with cutaneous melanoma with telomerase-specific peptides
Cancer Immunol Immunother, 60 (11), 1553-64
DOI 10.1007/s00262-011-1061-z, PubMed 21681371 -
Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7
Eur J Immunol, 41 (11), 3135-45
DOI 10.1002/eji.201141558, PubMed 21898381 -
Side population cells in highly enriched CD34-positive cells from peripheral blood progenitor cells identify an immature subtype of hematopoietic progenitor cells but do not predict time to engraftment in patients treated with high-dose therapy
Eur J Haematol, 87 (6), 494-502
DOI 10.1111/j.1600-0609.2011.01681.x, PubMed 21752097 -
Socio-demographic determinants of infant neurodevelopment at 18 months of age: Mother-Child Cohort (Rhea Study) in Crete, Greece
Infant Behav Dev, 35 (1), 48-59
DOI 10.1016/j.infbeh.2011.09.005, PubMed 22018719 -
Telomerase peptide vaccination combined with temozolomide: a clinical trial in stage IV melanoma patients
Clin Cancer Res, 17 (13), 4568-80
DOI 10.1158/1078-0432.CCR-11-0184, PubMed 21586625 -
LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome
Haematologica, 96 (7), 980-6
DOI 10.3324/haematol.2011.040568, PubMed 21459790 -
Galectin-1 and -3 gene silencing in immature and mature dendritic cells enhances T cell activation and interferon-γ production
J Leukoc Biol, 91 (3), 461-7
DOI 10.1189/jlb.0711361, PubMed 22167721 -
Promises and challenges in developing RNAi as a research tool and therapy
Methods Mol Biol, 703, 173-87
DOI 10.1007/978-1-59745-248-9_12, PubMed 21125490 -
New insights into mesenchymal stromal cell-mediated T-cell suppression through galectins
Scand J Immunol, 73 (2), 79-84
DOI 10.1111/j.1365-3083.2010.02491.x, PubMed 21198747 -
A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation
Biochem J, 436 (2), 371-85
DOI 10.1042/BJ20101493, PubMed 21388347 -
hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
Cancer Immunol Immunother, 60 (6), 809-18
DOI 10.1007/s00262-011-0991-9, PubMed 21365467 -
B7-H3 contributes to the metastatic capacity of melanoma cells by modulation of known metastasis-associated genes
Int J Cancer, 130 (10), 2282-90
DOI 10.1002/ijc.26238, PubMed 21671471 -
The amount of DNA damage needed to activate the radiation-induced G2 checkpoint varies between single cells
Radiother Oncol, 101 (1), 24-7
DOI 10.1016/j.radonc.2011.05.060, PubMed 21722983 -
The mild inflammatory response in febrile neutropenic lymphoma patients with low risk of complications is more pronounced in patients receiving tobramycin once daily compared with three times daily
Scand J Immunol, 74 (6), 632-9
DOI 10.1111/j.1365-3083.2011.02618.x, PubMed 21883353 -
Clinical significance of the WHO grades of follicular lymphoma in a population-based cohort of 505 patients with long follow-up times
Br J Haematol, 156 (2), 225-33
DOI 10.1111/j.1365-2141.2011.08942.x, PubMed 22126847 -
A practical approach to T-cell receptor cloning and expression
PLoS One, 6 (11), e27930
DOI 10.1371/journal.pone.0027930, PubMed 22132171 -
Translocation of exogenous FGF1 into cytosol and nucleus is a periodic event independent of receptor kinase activity
Exp Cell Res, 317 (7), 1005-15
DOI 10.1016/j.yexcr.2011.01.003, PubMed 21223966
Publications 2010
-
Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma
Int J Cancer, 126 (6), 1339-52
DOI 10.1002/ijc.24859, PubMed 19711348 -
Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif
Leukemia, 24 (11), 1901-9
DOI 10.1038/leu.2010.186, PubMed 20844564 -
Non-MHC-dependent redirected T cells against tumor cells
Methods Mol Biol, 629, 453-93
DOI 10.1007/978-1-60761-657-3_28, PubMed 20387166 -
Transiently redirected T cells for adoptive transfer
Cytotherapy, 13 (5), 629-40
DOI 10.3109/14653249.2010.542461, PubMed 21174490 -
TGF-β-induced growth inhibition in B-cell lymphoma correlates with Smad1/5 signalling and constitutively active p38 MAPK
BMC Immunol, 11, 57
DOI 10.1186/1471-2172-11-57, PubMed 21092277 -
Presence of STRA-STRB linked streptomycin-resistance genes in clinical isolate of Escherichia coil 2418
Arch Inst Pasteur Tunis, 87 (1-2), 77-81
PubMed 21598829 -
Light-induced gene expression using messenger RNA molecules
Oligonucleotides, 20 (1), 1-6
DOI 10.1089/oli.2009.0209, PubMed 20038251 -
Increased miR-21 expression during human monocyte differentiation into DCs
Front Biosci (Elite Ed), 2 (3), 818-28
DOI 10.2741/e143, PubMed 20515755 -
Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma
Cell, 142 (5), 699-713
DOI 10.1016/j.cell.2010.07.044, PubMed 20813259 -
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
Nature, 463 (7277), 88-92
DOI 10.1038/nature08638, PubMed 20054396 -
Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones
Blood, 116 (9), 1489-97
DOI 10.1182/blood-2010-03-272278, PubMed 20505157 -
Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis
Proc Natl Acad Sci U S A, 107 (27), 12233-8
DOI 10.1073/pnas.0915112107, PubMed 20566843 -
Recent advances in hematopoietic stem cell transplantation and perspectives of RNAi applications
Methods Mol Biol, 629, 507-23
DOI 10.1007/978-1-60761-657-3_30, PubMed 20387168 -
Cell wall anchoring of the 37-kilodalton oncofetal antigen by Lactobacillus plantarum for mucosal cancer vaccine delivery
Appl Environ Microbiol, 76 (21), 7359-62
DOI 10.1128/AEM.01031-10, PubMed 20851975 -
Both copy number and sequence variations affect expression of human DEFB4
Genes Immun, 11 (6), 458-66
DOI 10.1038/gene.2010.19, PubMed 20445567 -
B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression
Proc Natl Acad Sci U S A, 107 (29), 12747-54
DOI 10.1073/pnas.1002057107, PubMed 20543139 -
A combined immunostimulatory and immunoinhibitory short interference RNA reduces hypercoagulability in a rat model of acute promyelocytic leukaemia
Thromb Haemost, 104 (2), 350-4
DOI 10.1160/TH09-12-0816, PubMed 20539915 -
Third International Conference on Cancer Vaccines/Adjuvants/Delivery for the Next Decade (CVADD 2009)
Expert Rev Vaccines, 9 (2), 119-23
DOI 10.1586/erv.09.157, PubMed 20109021 -
[We know more than we can understand]
Tidsskr Nor Laegeforen, 130 (22), 2217
DOI 10.4045/tidsskr.10.1000, PubMed 21109831 -
Optimized protocols for siRNA delivery into monocytes and dendritic cells
Methods Mol Biol, 629, 71-85
DOI 10.1007/978-1-60761-657-3_5, PubMed 20387143 -
Oncogenically active MYD88 mutations in human lymphoma
Nature, 470 (7332), 115-9
DOI 10.1038/nature09671, PubMed 21179087 -
Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection
PLoS Pathog, 6 (12), e1001227
DOI 10.1371/journal.ppat.1001227, PubMed 21187913 -
Ex vivo expansion protocol for human tumor specific T cells for adoptive T cell therapy
J Immunol Methods, 355 (1-2), 52-60
DOI 10.1016/j.jim.2010.02.004, PubMed 20171968 -
Cooperative epigenetic modulation by cancer amplicon genes
Cancer Cell, 18 (6), 590-605
DOI 10.1016/j.ccr.2010.11.013, PubMed 21156283 -
Long-term muscular outcome and predisposing and prognostic factors in juvenile dermatomyositis: A case-control study
Arthritis Care Res (Hoboken), 62 (8), 1103-11
DOI 10.1002/acr.20203, PubMed 20506141 -
Recent advances in small interfering RNA sensing by the immune system
N Biotechnol, 27 (3), 236-42
DOI 10.1016/j.nbt.2010.02.015, PubMed 20219711 -
Advances in RNA sensing by the immune system: separation of siRNA unwanted effects from RNA interference
Methods Mol Biol, 629, 33-52
DOI 10.1007/978-1-60761-657-3_3, PubMed 20387141 -
What are the key targeted delivery technologies of siRNA now?
Methods Mol Biol, 629, 93-107
DOI 10.1007/978-1-60761-657-3_7, PubMed 20387145 -
Development of TLR7/8 small RNA antagonists
Methods Mol Biol, 629, 387-94
DOI 10.1007/978-1-60761-657-3_25, PubMed 20387163 -
Modulation of dendritic cell maturation and function by siRNA-bearing 5'-triphosphate
Methods Mol Biol, 629, 395-404
DOI 10.1007/978-1-60761-657-3_26, PubMed 20387164 -
Overcoming self-tolerance to tumour cells
Methods Mol Biol, 629, 495-505
DOI 10.1007/978-1-60761-657-3_29, PubMed 20387167 -
RNA therapeutics: function, design, and delivery. Preface
Methods Mol Biol, 629, v-vii
DOI 10.1007/978-1-60761-657-3, PubMed 20394129 -
Profiling of miRNA expression and prediction of target genes
Methods Mol Biol, 629, 257-71
DOI 10.1007/978-1-60761-657-3_16, PubMed 20387154 -
Evidence for the involvement of galectin-3 in mesenchymal stem cell suppression of allogeneic T-cell proliferation
Scand J Immunol, 71 (4), 267-74
DOI 10.1111/j.1365-3083.2010.02378.x, PubMed 20384870 -
Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins
Int J Oncol, 38 (2), 385-90
DOI 10.3892/ijo.2010.869, PubMed 21165555 -
[Close cooperation, but not oversteering]
Tidsskr Nor Laegeforen, 130 (6), 590-1
DOI 10.4045/tidsskr.10.0153, PubMed 20348990 -
[Leadership and academic competence]
Tidsskr Nor Laegeforen, 130 (6), 591
DOI 10.4045/tidsskr.10.0217, PubMed 20348994 -
Formation of biocompatible nanocapsules with emulsion core and pegylated shell by polyelectrolyte multilayer adsorption
Langmuir, 26 (15), 12592-7
DOI 10.1021/la102061s, PubMed 20604580 -
Systemic delivery of synthetic siRNAs
Methods Mol Biol, 629, 87-91
DOI 10.1007/978-1-60761-657-3_6, PubMed 20387144 -
Splice variants of enigma homolog, differentially expressed during heart development, promote or prevent hypertrophy
Cardiovasc Res, 86 (3), 374-82
DOI 10.1093/cvr/cvq023, PubMed 20097676
Publications 2009
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Targeting stromal-cancer cell interactions with siRNAs
Methods Mol Biol, 487, 243-66
DOI 10.1007/978-1-60327-547-7_12, PubMed 19301651 -
Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
Methods Mol Biol, 524, 273-85
DOI 10.1007/978-1-59745-450-6_20, PubMed 19377952 -
Improving the efficacy of cancer immunotherapy
Eur J Cancer, 45 (8), 1424-31
DOI 10.1016/j.ejca.2008.12.017, PubMed 19167214 -
Secretion of tumor-specific antigen by myeloma cells is required for cancer immunosurveillance by CD4+ T cells
Cancer Res, 69 (14), 5901-7
DOI 10.1158/0008-5472.CAN-08-4816, PubMed 19567679 -
Modulation of dendritic cell maturation and function with mono- and bifunctional small interfering RNAs targeting indoleamine 2,3-dioxygenase
Immunology, 128 (1 Suppl), e837-48
DOI 10.1111/j.1365-2567.2009.03093.x, PubMed 19740345 -
Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3
Ultrastruct Pathol, 33 (4), 175-81
DOI 10.1080/01913120903086072, PubMed 19728235 -
[Myositis-specific autoantibodies]
Tidsskr Nor Laegeforen, 129 (16), 1631-4
DOI 10.4045/tidsskr.09.35501, PubMed 19721478 -
Evidence for the involvement of FAM110C protein in cell spreading and migration
Cell Signal, 21 (12), 1866-73
DOI 10.1016/j.cellsig.2009.08.001, PubMed 19698782 -
[Molecular diagnosis of malignant lymphomas]
Tidsskr Nor Laegeforen, 129 (22), 2352-6
DOI 10.4045/tidsskr.09.0704, PubMed 19935935 -
Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion
Blood, 114 (16), 3431-8
DOI 10.1182/blood-2009-05-223958, PubMed 19641184 -
c-Met signaling promotes IL-6-induced myeloma cell proliferation
Eur J Haematol, 82 (4), 277-87
DOI 10.1111/j.1600-0609.2009.01212.x, PubMed 19187270 -
Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs
Nucleic Acids Res, 37 (22), 7560-9
DOI 10.1093/nar/gkp835, PubMed 19815667 -
Dendritic Cells Loaded with Tumor Antigens and a Dual Immunostimulatory and Anti-Interleukin 10-Specific Small Interference RNA Prime T Lymphocytes against Leukemic Cells
Transl Oncol, 2 (4), 242-6
DOI 10.1593/tlo.09154, PubMed 19956385 -
Cancer vaccination with telomerase peptide GV1001
Expert Opin Investig Drugs, 18 (5), 687-94
DOI 10.1517/13543780902897631, PubMed 19388882 -
[Nobel Prize for mitotic clock]
Tidsskr Nor Laegeforen, 129 (23), 2470
DOI 10.4045/tidsskr.09.1298, PubMed 19997132 -
Unconventional cytokine profiles and development of T cell memory in long-term survivors after cancer vaccination
Cancer Immunol Immunother, 58 (10), 1609-26
DOI 10.1007/s00262-009-0670-2, PubMed 19221745 -
Array-based DNA methylation profiling in follicular lymphoma
Leukemia, 23 (10), 1858-66
DOI 10.1038/leu.2009.114, PubMed 19587707 -
Dendritic cells in cytomegalovirus infection: viral evasion and host countermeasures
APMIS, 117 (5-6), 413-26
DOI 10.1111/j.1600-0463.2009.02449.x, PubMed 19400865 -
Deciphering the code of innate immunity recognition of siRNAs
Methods Mol Biol, 487, 41-59
DOI 10.1007/978-1-60327-547-7_2, PubMed 19301641 -
Targeted delivery of antisense oligonucleotides and siRNAs into mammalian cells
Methods Mol Biol, 487, 61-82
DOI 10.1007/978-1-60327-547-7_3, PubMed 19301642 -
Does our current understanding of immune tolerance, autoimmunity, and immunosuppressive mechanisms facilitate the design of efficient cancer vaccines?
Scand J Immunol, 70 (6), 516-25
DOI 10.1111/j.1365-3083.2009.02326.x, PubMed 19906192 -
Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs
Int J Mol Med, 23 (1), 33-9
DOI 10.3892/ijmm_00000098, PubMed 19082504 -
NOD2/CARD15 on bone marrow CD34+ hematopoietic cells mediates induction of cytokines and cell differentiation
J Leukoc Biol, 85 (6), 939-46
DOI 10.1189/jlb.1008650, PubMed 19244164 -
SNX4 in complex with clathrin and dynein: implications for endosome movement
PLoS One, 4 (6), e5935
DOI 10.1371/journal.pone.0005935, PubMed 19529763 -
β-arrestins attenuate p38-mediated endosome to Golgi transport
Cell Microbiol, 11 (5), 796-807
DOI 10.1111/j.1462-5822.2009.01292.x, PubMed 19159388 -
Dendritic cells engineered to express defined allo-HLA peptide complexes induce antigen-specific cytotoxic T cells efficiently killing tumour cells
Scand J Immunol, 69 (4), 319-28
DOI 10.1111/j.1365-3083.2008.02223.x, PubMed 19284496 -
Characterization of clathrin and Syk interaction upon Shiga toxin binding
Cell Signal, 21 (7), 1161-8
DOI 10.1016/j.cellsig.2009.03.005, PubMed 19289168 -
Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion
Nat Med, 15 (6), 633-40
DOI 10.1038/nm.1968, PubMed 19465928
Publications 2008
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Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts
Front Biosci, 13, 5571-9
DOI 10.2741/3100, PubMed 18508606 -
The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling
Oncogene, 27 (39), 5182-94
DOI 10.1038/onc.2008.157, PubMed 18469852 -
Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection
J Exp Med, 205 (9), 2111-24
DOI 10.1084/jem.20072076, PubMed 18695005 -
Bone marrow stroma cells regulate TIEG1 expression in acute lymphoblastic leukemia cells: role of TGFbeta/BMP-6 and TIEG1 in chemotherapy escape
Int J Cancer, 123 (12), 2759-66
DOI 10.1002/ijc.23833, PubMed 18798273 -
Signaling through ephrin-A ligand leads to activation of Src-family kinases, Akt phosphorylation, and inhibition of antigen receptor-induced apoptosis
J Leukoc Biol, 84 (4), 1183-91
DOI 10.1189/jlb.1207829, PubMed 18593733 -
EBV infection renders B cells resistant to growth inhibition via adenylyl cyclase
Cell Signal, 20 (6), 1169-78
DOI 10.1016/j.cellsig.2008.02.007, PubMed 18406106 -
Oncogenic CARD11 mutations in human diffuse large B cell lymphoma
Science, 319 (5870), 1676-9
DOI 10.1126/science.1153629, PubMed 18323416 -
Stromal gene signatures in large-B-cell lymphomas
N Engl J Med, 359 (22), 2313-23
DOI 10.1056/NEJMoa0802885, PubMed 19038878 -
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways
Proc Natl Acad Sci U S A, 105 (36), 13520-5
DOI 10.1073/pnas.0804295105, PubMed 18765795 -
Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection
J Clin Invest, 118 (5), 1835-45
DOI 10.1172/JCI33402, PubMed 18398508 -
Enigma homolog 1 scaffolds protein kinase D1 to regulate the activity of the cardiac L-type voltage-gated calcium channel
Cardiovasc Res, 78 (3), 458-65
DOI 10.1093/cvr/cvn052, PubMed 18296710 -
beta-catenin is involved in N-cadherin-dependent adhesion, but not in canonical Wnt signaling in E2A-PBX1-positive B acute lymphoblastic leukemia cells
Exp Hematol, 37 (2), 225-33
DOI 10.1016/j.exphem.2008.10.007, PubMed 19101069 -
The presence of TP53 mutation at diagnosis of follicular lymphoma identifies a high-risk group of patients with shortened time to disease progression and poorer overall survival
Blood, 112 (8), 3126-9
DOI 10.1182/blood-2008-05-154013, PubMed 18628487 -
Mucosal vaccination with phage-displayed tumour antigens identified through proteomics-based strategy inhibits the growth and metastasis of 4T1 breast adenocarcinoma
Int J Oncol, 32 (1), 241-7
PubMed 18097564 -
Does the understanding of immune activation by RNA predict the design of safe siRNAs?
Front Biosci, 13, 4379-92
DOI 10.2741/3011, PubMed 18508517 -
Expression profiling of microRNAs in cancer cells: technical considerations
Methods Mol Biol, 439, 179-90
DOI 10.1007/978-1-59745-188-8_12, PubMed 18370103 -
Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus
Mol Cell Biol, 28 (12), 4129-41
DOI 10.1128/MCB.02117-07, PubMed 18411303 -
Vector-based delivery of siRNAs: in vitro and in vivo challenges
Front Biosci, 13, 3488-93
DOI 10.2741/2943, PubMed 18508450 -
Treatment with autologous bone marrow mononuclear cells in patients with critical lower limb ischaemia. A pilot study
Scand J Surg, 97 (1), 56-62
DOI 10.1177/145749690809700108, PubMed 18450207
Publications 2007
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Target validation using RNA interference in solid tumors
Methods Mol Biol, 361, 227-38
DOI 10.1385/1-59745-208-4:227, PubMed 17172715 -
Identification of prostate cancer antigens by automated high-throughput filter immunoscreening
J Immunol Methods, 330 (1-2), 12-23
DOI 10.1016/j.jim.2007.10.011, PubMed 18045611 -
[A three-year-old boy with bullous skin eruptions and paresis]
Tidsskr Nor Laegeforen, 127 (15), 1950-2
PubMed 17708060 -
Expression of S100A4 by a variety of cell types present in the tumor microenvironment of human breast cancer
Int J Cancer, 121 (7), 1433-44
DOI 10.1002/ijc.22850, PubMed 17565747 -
Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
Methods Mol Biol, 360, 335-48
DOI 10.1385/1-59745-165-7:335, PubMed 17172738 -
Vitamin A potentiates CpG-mediated memory B-cell proliferation and differentiation: involvement of early activation of p38MAPK
Blood, 109 (9), 3865-72
DOI 10.1182/blood-2006-09-046748, PubMed 17209053 -
Impaired expression of indoleamine 2, 3-dioxygenase in monocyte-derived dendritic cells in response to Toll-like receptor-7/8 ligands
Immunology, 123 (2), 263-71
DOI 10.1111/j.1365-2567.2007.02695.x, PubMed 17725606 -
Characterization of the FAM110 gene family
Genomics, 90 (1), 14-27
DOI 10.1016/j.ygeno.2007.03.002, PubMed 17499476 -
Ephrin-A1 stimulates migration of CD8+CCR7+ T lymphocytes
Eur J Immunol, 37 (8), 2326-36
DOI 10.1002/eji.200737111, PubMed 17634955 -
Characterization of early stages of human B cell development by gene expression profiling
J Immunol, 179 (6), 3662-71
DOI 10.4049/jimmunol.179.6.3662, PubMed 17785802 -
A full scale comparative study of methods for generation of functional Dendritic cells for use as cancer vaccines
BMC Cancer, 7, 119
DOI 10.1186/1471-2407-7-119, PubMed 17608923 -
mRNA transfection of DC in the immature or mature state: comparable in vitro priming of Th and cytotoxic T lymphocytes against DC electroporated with tumor cell line-derived mRNA
Cytotherapy, 9 (6), 587-92
DOI 10.1080/14653240701466354, PubMed 17882723 -
Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma
J Exp Med, 204 (3), 633-43
DOI 10.1084/jem.20062041, PubMed 17353367 -
Discovery of differentially expressed genes: technical considerations
Methods Mol Biol, 360, 115-29
DOI 10.1385/1-59745-165-7:115, PubMed 17172727 -
Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signature
J Clin Oncol, 25 (10), 1216-22
DOI 10.1200/JCO.2006.08.4251, PubMed 17296973 -
Main approaches to target discovery and validation
Methods Mol Biol, 360, 1-12
DOI 10.1385/1-59745-165-7:1, PubMed 17172722 -
An overview of the immune system and technical advances in tumor antigen discovery and validation
Methods Mol Biol, 360, 277-318
DOI 10.1385/1-59745-165-7:277, PubMed 17172735 -
RNA interference and innate immunity
Adv Drug Deliv Rev, 59 (2-3), 153-63
DOI 10.1016/j.addr.2007.03.006, PubMed 17459518 -
TLR agonists induce the differentiation of human bone marrow CD34+ progenitors into CD11c+ CD80/86+ DC capable of inducing a Th1-type response
Eur J Immunol, 37 (10), 2834-46
DOI 10.1002/eji.200737112, PubMed 17853407 -
Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
Biochem Biophys Res Commun, 361 (1), 122-6
DOI 10.1016/j.bbrc.2007.06.177, PubMed 17658482 -
Druggable signaling proteins
Methods Mol Biol, 361, 1-24
DOI 10.1385/1-59745-208-4:1, PubMed 17172705 -
Treatment options and individualized medicine
Methods Mol Biol, 361, 327-40
DOI 10.1385/1-59745-208-4:327, PubMed 17172721 -
Inhibitory effects and target genes of bone morphogenetic protein 6 in Jurkat TAg cells
Eur J Immunol, 37 (10), 2937-48
DOI 10.1002/eji.200636759, PubMed 17899540 -
Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival
Blood, 109 (11), 4599-606
DOI 10.1182/blood-2006-08-039859, PubMed 17299095 -
Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway
Cancer Res, 67 (3), 1038-45
DOI 10.1158/0008-5472.CAN-06-2295, PubMed 17283136 -
Non-Hodgkin lymphoma with t(14;18): clonal evolution patterns and cytogenetic-pathologic-clinical correlations
J Cancer Res Clin Oncol, 133 (7), 455-70
DOI 10.1007/s00432-006-0188-3, PubMed 17235551
Publications 2006
-
Influence of light fluence rate on the effects of photodynamic therapy in an orthotopic rat glioma model
J Neurosurg, 104 (1), 109-17
DOI 10.3171/jns.2006.104.1.109, PubMed 16509154 -
Telomerase peptide vaccination of patients with non-resectable pancreatic cancer: A dose escalating phase I/II study
Br J Cancer, 95 (11), 1474-82
DOI 10.1038/sj.bjc.6603437, PubMed 17060934 -
Adenosine as a metabolic regulator of tissue function: production of adenosine by cytoplasmic 5'-nucleotidases
Acta Biochim Pol, 53 (2), 269-78
PubMed 16770441 -
Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
Cancer Immunol Immunother, 55 (12), 1553-64
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Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
J Mol Biol, 365 (1), 90-108
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Molecular diagnosis of Burkitt's lymphoma
N Engl J Med, 354 (23), 2431-42
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Wnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesis
BMC Immunol, 7, 13
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Evaluation of sieving matrices used to separate alleles by cycling temperature capillary electrophoresis
Electrophoresis, 27 (10), 1878-85
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Design of bifunctional siRNAs: combining immunostimulation and gene-silencing in one single siRNA molecule
Biochem Biophys Res Commun, 352 (3), 642-9
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Prospects for vaccine therapy for pancreatic cancer
Best Pract Res Clin Gastroenterol, 20 (2), 299-314
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Transcriptional targeting of small interfering RNAs into cancer cells
Biochem Biophys Res Commun, 350 (4), 854-9
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Induction of hypoxia-inducible factor-1alpha overexpression by cobalt chloride enhances cellular resistance to photodynamic therapy
Cancer Lett, 244 (2), 182-9
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BMP-6 inhibits human bone marrow B lymphopoiesis--upregulation of Id1 and Id3
Exp Hematol, 34 (1), 72-81
DOI 10.1016/j.exphem.2005.09.010, PubMed 16413393 -
[Cancer vaccines]
Tidsskr Nor Laegeforen, 126 (22), 2969-73
PubMed 17117197 -
Immuno-gene therapy of cancer with tumour-mRNA transfected dendritic cells
Cancer Immunol Immunother, 55 (11), 1432-42
DOI 10.1007/s00262-006-0161-7, PubMed 16612595 -
T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
Cancer Immunol Immunother, 56 (5), 659-75
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Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
Cancer Gene Ther, 13 (10), 905-18
DOI 10.1038/sj.cgt.7700961, PubMed 16710345 -
Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction
N Engl J Med, 355 (12), 1199-209
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Wnt3A activates canonical Wnt signalling in acute lymphoblastic leukaemia (ALL) cells and inhibits the proliferation of B-ALL cell lines
Br J Haematol, 136 (3), 400-13
DOI 10.1111/j.1365-2141.2006.06442.x, PubMed 17156404 -
CSPP and CSPP-L associate with centrosomes and microtubules and differently affect microtubule organization
J Cell Physiol, 209 (1), 199-210
DOI 10.1002/jcp.20725, PubMed 16826565 -
DNA damage responses in cell cycle G2 phase and mitosis--tracking and targeting
Anticancer Res, 26 (3A), 1909-16
PubMed 16827124 -
Characterization of novel alternative splicing sites in human telomerase reverse transcriptase (hTERT): analysis of expression and mutual correlation in mRNA isoforms from normal and tumour tissues
BMC Mol Biol, 7, 26
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Innate sensing of self and non-self RNAs by Toll-like receptors
Trends Mol Med, 12 (4), 167-76
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Ribozymes and siRnas: from structure to preclinical applications
Handb Exp Pharmacol (173), 223-42
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Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: a central role for 2'-hydroxyl uridines in immune responses
Eur J Immunol, 36 (5), 1222-30
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RNA interference below the immune radar
Nat Biotechnol, 24 (5), 521-2
DOI 10.1038/nbt0506-521, PubMed 16680132 -
RNAi therapy: antibodies guide the way
Gene Ther, 13 (3), 194-5
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Signaling through toll-like receptor 7/8 induces the differentiation of human bone marrow CD34+ progenitor cells along the myeloid lineage
J Mol Biol, 364 (5), 945-54
DOI 10.1016/j.jmb.2006.09.054, PubMed 17049554 -
Molecular basis for the immunostimulatory potency of small interfering RNAs
J Biomed Biotechnol, 2006 (4), 23429
DOI 10.1155/JBB/2006/23429, PubMed 17057361 -
RNA interference
J Biomed Biotechnol, 2006 (4), 89018
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Gain of chromosome 6p is an infrequent cause of increased PIM1 expression in B-cell non-Hodgkin's lymphomas
Leukemia, 20 (3), 539-42
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PI3K/Akt-dependent Epo-induced signalling and target genes in human early erythroid progenitor cells
Br J Haematol, 135 (1), 117-28
DOI 10.1111/j.1365-2141.2006.06252.x, PubMed 16965383 -
Computational prediction of microRNAs encoded in viral and other genomes
J Biomed Biotechnol, 2006 (4), 95270
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Molecular biology on the ICU. From understanding to treating sepsis
Minerva Anestesiol, 72 (5), 255-67
PubMed 16675935 -
Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease
Genes Immun, 7 (1), 11-8
DOI 10.1038/sj.gene.6364263, PubMed 16222343
Publications 2005
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Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression-based survival prediction
Blood, 106 (9), 3183-90
DOI 10.1182/blood-2005-04-1399, PubMed 16046532 -
Review of denaturant capillary electrophoresis in DNA variation analysis
Electrophoresis, 26 (13), 2520-30
DOI 10.1002/elps.200410403, PubMed 15934053 -
Targeting PBR by hexaminolevulinate-mediated photodynamic therapy induces apoptosis through translocation of apoptosis-inducing factor in human leukemia cells
Cancer Res, 65 (23), 11051-60
DOI 10.1158/0008-5472.CAN-05-0510, PubMed 16322255 -
Translocation t(14;18) and gain of chromosome 18/BCL2: effects on BCL2 expression and apoptosis in B-cell non-Hodgkin's lymphomas
Leukemia, 19 (12), 2313-23
DOI 10.1038/sj.leu.2403954, PubMed 16193090 -
Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL
J Exp Med, 202 (8), 1109-19
DOI 10.1084/jem.20050162, PubMed 16216889 -
Evaluation of dendritic cells loaded with apoptotic cancer cells or expressing tumour mRNA as potential cancer vaccines against leukemia
BMC Cancer, 5, 20
DOI 10.1186/1471-2407-5-20, PubMed 15720715 -
Preclinical evaluation of autologous dendritic cells transfected with mRNA or loaded with apoptotic cells for immunotherapy of high-risk neuroblastoma
Cancer Gene Ther, 12 (8), 699-707
DOI 10.1038/sj.cgt.7700820, PubMed 15846368 -
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1
BMC Immunol, 6, 9
DOI 10.1186/1471-2172-6-9, PubMed 15877825 -
Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
Cancer Gene Ther, 12 (6), 579-91
DOI 10.1038/sj.cgt.7700837, PubMed 15818380 -
Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection
J Infect Dis, 191 (7), 1169-79
DOI 10.1086/428502, PubMed 15747254 -
[Matrix metalloproteinases and their inhibitors in lung cancer with malignant pleural effusion]
Pneumologie, 59 (8), 523-8
DOI 10.1055/s-2005-870966, PubMed 16110415 -
Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
Br J Cancer, 93 (7), 749-56
DOI 10.1038/sj.bjc.6602761, PubMed 16136047 -
Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization
Oncogene, 24 (7), 1159-73
DOI 10.1038/sj.onc.1208267, PubMed 15580290 -
Systematic search for natural antisense transcripts in eukaryotes (review)
Int J Mol Med, 15 (2), 197-203
PubMed 15647831 -
Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization
J Mol Biol, 348 (5), 1079-90
DOI 10.1016/j.jmb.2005.03.013, PubMed 15854645 -
siRNA delivery in vivo
Methods Mol Biol, 309, 237-49
DOI 10.1385/1-59259-935-4:237, PubMed 15990404 -
On the delivery of small interfering RNAs into mammalian cells
Expert Opin Drug Deliv, 2 (4), 639-51
DOI 10.1517/17425247.2.4.639, PubMed 16296791 -
Ribozymes, DNAzymes and small interfering RNAs as therapeutics
Curr Drug Targets, 6 (6), 647-53
DOI 10.2174/1389450054863653, PubMed 16178798 -
High-throughput analysis of microRNA gene expression using sensitive probes
Methods Mol Biol, 309, 311-20
DOI 10.1385/1-59259-935-4:311, PubMed 15990410 -
Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs
Methods Mol Biol, 309, 83-91
DOI 10.1385/1-59259-935-4:083, PubMed 15990399 -
PU.1 protein expression has a positive linear association with protein expression of germinal centre B cell genes including BCL-6, CD10, CD20 and CD22: identification of PU.1 putative binding sites in the BCL-6 promotor
J Pathol, 206 (3), 312-9
DOI 10.1002/path.1777, PubMed 15892171 -
CD10+ stromal cells form B-lymphocyte maturation niches in the human bone marrow
J Pathol, 205 (3), 311-7
DOI 10.1002/path.1705, PubMed 15682430 -
Characterization of a novel Eph receptor tyrosine kinase, EphA10, expressed in testis
Biochim Biophys Acta, 1723 (1-3), 1-7
DOI 10.1016/j.bbagen.2005.01.011, PubMed 15777695
Publications 2004
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Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice
Cancer Res, 64 (15), 5378-84
DOI 10.1158/0008-5472.CAN-04-0961, PubMed 15289345 -
Resolving the evolutionary paradox of genetic instability: a cost-benefit analysis of DNA repair in changing environments
FEBS Lett, 563 (1-3), 7-12
DOI 10.1016/S0014-5793(04)00282-0, PubMed 15063714 -
Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
Proteomics, 4 (9), 2572-82
DOI 10.1002/pmic.200300768, PubMed 15352232 -
Transcriptional activation of the SH2D2A gene is dependent on a cyclic adenosine 5'-monophosphate-responsive element in the proximal SH2D2A promoter
J Immunol, 172 (10), 6144-51
DOI 10.4049/jimmunol.172.10.6144, PubMed 15128801 -
Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells
N Engl J Med, 351 (21), 2159-69
DOI 10.1056/NEJMoa041869, PubMed 15548776 -
A new ephrin-A1 isoform (ephrin-A1b) with altered receptor binding properties abrogates the cleavage of ephrin-A1a
Biochem J, 379 (Pt 1), 39-46
DOI 10.1042/BJ20031619, PubMed 14692877 -
Serological cloning of cancer/testis antigens expressed in prostate cancer using cDNA phage surface display
Cancer Immunol Immunother, 53 (5), 431-8
DOI 10.1007/s00262-003-0458-8, PubMed 14747957 -
NY-ESO-1 protein expression and humoral immune responses in prostate cancer
Prostate, 59 (4), 440-7
DOI 10.1002/pros.20025, PubMed 15065093 -
Characterization of a novel immunoglobulin-like domain containing receptor
Biochem Biophys Res Commun, 323 (3), 970-8
DOI 10.1016/j.bbrc.2004.08.188, PubMed 15381095 -
Repetitive 5-aminolevulinic acid mediated photodynamic therapy of rat glioma
P SOC PHOTO-OPT INS, 5312, 405-414
DOI 10.1117/12.527395 -
Gene expression analysis of peripheral T cells in a subgroup of common variable immunodeficiency shows predominance of CCR7(-) effector-memory T cells
Clin Exp Immunol, 138 (2), 278-89
DOI 10.1111/j.1365-2249.2004.02630.x, PubMed 15498038 -
Inhibition of gene expression by nucleic acid enzymes in rodent models of human disease
Methods Mol Biol, 252, 451-6
DOI 10.1385/1-59259-746-7:451, PubMed 15017070 -
Analysis of the autoantibody repertoire in Burkitt's lymphoma patients: frequent response against the transcription factor ATF-2
Cancer Immunol Immunother, 53 (12), 1119-26
DOI 10.1007/s00262-004-0558-0, PubMed 15185015 -
Experimental attempt to introduce a vaccine therapy by using DC-developed from CD34+cells
NATO SCI SER I LIFE, 361, 134 -
Identification of genes differentially expressed in breast cancer cell line SKBR3: potential identification of new prognostic biomarkers
Int J Mol Med, 14 (2), 217-22
PubMed 15254768 -
Gene-array analysis of glioma cells after treatment with an anti-PKCalpha siRNA: a general protocol
Methods Mol Biol, 252, 493-500
DOI 10.1385/1-59259-746-7:493, PubMed 15017074 -
Adapting email functionality for mobile terminals
LECT NOTES COMPUT SC, 3283, 199-206 -
Development of a clinical grade procedure for generation of mRNA transfected dendritic cells from purified frozen CD34(+) blood progenitor cells
Int J Immunopathol Pharmacol, 17 (3), 255-63
DOI 10.1177/039463200401700305, PubMed 15461859 -
Expression and functional effects of Eph receptor tyrosine kinase A family members on Langerhans like dendritic cells
BMC Immunol, 5, 9
DOI 10.1186/1471-2172-5-9, PubMed 15176971 -
Butyrate response factor 1 is regulated by parathyroid hormone and bone morphogenetic protein-2 in osteoblastic cells
Biochem Biophys Res Commun, 324 (1), 218-23
DOI 10.1016/j.bbrc.2004.09.030, PubMed 15465005 -
An experimental approach for systematic identification of antisense transcripts
Discov Med, 4 (20), 58-60
PubMed 20705023 -
Selection of peptides for specific delivery of oligonucleotides into cancer cells
Methods Mol Biol, 252, 569-80
DOI 10.1385/1-59259-746-7:569, PubMed 15017081 -
Plasma levels of transforming growth factor-1beta and alpha2-macroglobulin before and after radical prostatectomy: association to clinicopathological parameters
Prostate, 61 (3), 201-8
DOI 10.1002/pros.20062, PubMed 15368477 -
Therapeutic siRNAs
Trends Pharmacol Sci, 25 (1), 22-8
DOI 10.1016/j.tips.2003.11.006, PubMed 14723975 -
Ribozyme- and siRNA-mediated mRNA degradation: a general introduction
Methods Mol Biol, 252, 1-8
DOI 10.1385/1-59259-746-7:001, PubMed 15017038 -
Therapeutic potential of small interfering RNAs
Drug Future, 29 (7), 741-750
DOI 10.1358/dof.2004.029.07.854171 -
Potential design rules and enzymatic synthesis of siRNAs
Methods Mol Biol, 252, 457-69
DOI 10.1385/1-59259-746-7:457, PubMed 15017071 -
Profiling microRNA expression using sensitive cDNA probes and filter arrays
Biotechniques, 37 (4), 574-6, 578-80
DOI 10.2144/04374ST01, PubMed 15517969 -
Systemic delivery of synthetic siRNAs
Methods Mol Biol, 252, 515-22
DOI 10.1385/1-59259-746-7:515, PubMed 15017077 -
Ephrin-A1 binding to CD4+ T lymphocytes stimulates migration and induces tyrosine phosphorylation of PYK2
Blood, 105 (7), 2869-76
DOI 10.1182/blood-2004-08-2981, PubMed 15585656
Publications 2003
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Human alpha2-macroglobulin: genotype-phenotype relation
Exp Neurol, 184 (1), 153-61
DOI 10.1016/s0014-4886(03)00110-9, PubMed 14637088 -
Evaluation of denaturing conditions in analysis of DNA variants applied to multi-capillary electrophoresis instruments
J. Sep. Sci., 26 (12-13), 1163-1168
DOI 10.1002/jssc.200301521 -
Approach to analysis of single nucleotide polymorphisms by automated constant denaturant capillary electrophoresis
Mutat Res, 526 (1-2), 75-83
DOI 10.1016/s0027-5107(03)00033-2, PubMed 12714185 -
Direct identification of all oncogenic mutants in KRAS exon 1 by cycling temperature capillary electrophoresis
Electrophoresis, 24 (1-2), 63-9
DOI 10.1002/elps.200390032, PubMed 12652573 -
Identification and physical mapping of genes expressed in the corpus luteum in cattle
Anim Genet, 34 (5), 325-33
DOI 10.1046/j.1365-2052.2003.01023.x, PubMed 14510667 -
Probing the specificity of human myeloma proteins with a random peptide phage library
Scand J Immunol, 57 (6), 583-90
DOI 10.1046/j.1365-3083.2003.01254.x, PubMed 12791097 -
DNA variants in the ATM gene are not associated with sporadic rectal cancer in a Norwegian population-based study
Int J Colorectal Dis, 19 (1), 49-54
DOI 10.1007/s00384-003-0519-7, PubMed 12827413 -
A protocol for generation of clinical grade mRNA-transfected monocyte-derived dendritic cells for cancer vaccines
Scand J Immunol, 58 (5), 578-86
DOI 10.1046/j.1365-3083.2003.01333.x, PubMed 14629630 -
Molecular heterogeneity in human osteosarcoma demonstrated by enriched mRNAs isolated by directional tag PCR subtraction cloning
Anticancer Res, 23 (3B), 2201-16
PubMed 12894494 -
Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma
J Exp Med, 198 (6), 851-62
DOI 10.1084/jem.20031074, PubMed 12975453 -
The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma
Cancer Cell, 3 (2), 185-97
DOI 10.1016/s1535-6108(03)00028-x, PubMed 12620412 -
Systematic identification of sense-antisense transcripts in mammalian cells
Nat Biotechnol, 22 (1), 104-8
DOI 10.1038/nbt925, PubMed 14704709 -
Selective targeting of cancer cells using synthetic peptides
Drug Resist Updat, 6 (6), 363-71
DOI 10.1016/j.drup.2003.11.002, PubMed 14744500 -
Generation of an effective anti-tumor immunity after immunization with xenogeneic antigens
Eur J Immunol, 33 (1), 38-45
DOI 10.1002/immu.200390005, PubMed 12594830 -
Cationic liposome-mediated delivery of siRNAs in adult mice
Biochem Biophys Res Commun, 312 (4), 1220-5
DOI 10.1016/j.bbrc.2003.11.057, PubMed 14652004 -
Gene silencing by systemic delivery of synthetic siRNAs in adult mice
J Mol Biol, 327 (4), 761-6
DOI 10.1016/s0022-2836(03)00181-5, PubMed 12654261 -
The human solute carrier SLC41A1 belongs to a novel eukaryotic subfamily with homology to prokaryotic MgtE Mg2+ transporters
Biochem Biophys Res Commun, 306 (3), 718-24
DOI 10.1016/s0006-291x(03)01030-1, PubMed 12810078
Publications 2002
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Melting gel techniques in single nucleotide polymorphism and mutation detection: From theory to automation
J. Sep. Sci., 25 (10-11), 637-647
DOI 10.1002/1615-9314(20020701)25:10/11<637::AID-JSSC637>3.0.CO;2-L -
Mutation detection in KRAS Exon 1 by constant denaturant capillary electrophoresis in 96 parallel capillaries
Anal Biochem, 304 (2), 200-5
DOI 10.1006/abio.2002.5629, PubMed 12009696 -
Reducing the cost of consumables used for ABI 310 genetic analyzer
Anal Biochem, 306 (1), 148-9
DOI 10.1006/abio.2002.5656, PubMed 12069426 -
Population screening of single-nucleotide polymorphisms exemplified by analysis of 8000 alleles
J Biomol Screen, 7 (6), 501-6
DOI 10.1177/1087057102238623, PubMed 14599347 -
Independent prognostic significance of HER-2 oncoprotein expression in pN0 prostate cancer undergoing curative radiotherapy
Int J Cancer, 99 (1), 100-5
DOI 10.1002/ijc.10286, PubMed 11948499 -
HLA-A3 restricted mutant ras specific cytotoxic T-lymphocytes induced by vaccination with T-helper epitopes
J Mol Med (Berl), 81 (1), 43-50
DOI 10.1007/s00109-002-0390-y, PubMed 12545248 -
Inhibition of HLA-DR assembly, transport, and loading by human cytomegalovirus glycoprotein US3: a novel mechanism for evading major histocompatibility complex class II antigen presentation
J Virol, 76 (21), 10929-41
DOI 10.1128/jvi.76.21.10929-10941.2002, PubMed 12368336 -
Targeting Raf-1 gene expression by a DNA enzyme inhibits juvenile myelomonocytic leukemia cell growth
Blood, 99 (11), 4147-53
DOI 10.1182/blood.v99.11.4147, PubMed 12010819 -
Characterization of the novel human transmembrane protein 9 (TMEM9) that localizes to lysosomes and late endosomes
Biochem Biophys Res Commun, 297 (4), 912-7
DOI 10.1016/s0006-291x(02)02228-3, PubMed 12359240 -
Gene silencing in mammalian cells by preformed small RNA duplexes
Biochem Biophys Res Commun, 295 (3), 744-8
DOI 10.1016/s0006-291x(02)00736-2, PubMed 12099702 -
[Tyrosine kinase receptor-ras-ERK signal transduction pathway as therapeutic tarfet in cancer]
Tidsskr Nor Laegeforen, 122 (2), 178-82
PubMed 11873574 -
Nonviral and viral gene transfer into different subsets of human dendritic cells yield comparable efficiency of transfection
J Immunother, 25 (6), 445-54
DOI 10.1097/00002371-200211000-00001, PubMed 12439342 -
Forebrain-specific promoter/enhancer D6 derived from the mouse Dach1 gene controls expression in neural stem cells
Neuroscience, 112 (4), 951-66
DOI 10.1016/s0306-4522(02)00053-2, PubMed 12088753 -
Characterization of the human ephrin-A4 promoter
Biochem J, 366 (Pt 2), 447-58
DOI 10.1042/BJ20011693, PubMed 12030849 -
Activation of phosphatidylinositol 3-kinase is important for erythropoietin-induced erythropoiesis from CD34(+) hematopoietic progenitor cells
Exp Hematol, 30 (9), 990-1000
DOI 10.1016/s0301-472x(02)00868-8, PubMed 12225790 -
Characterization of a novel human endogenous retrovirus, HERV-H/F, expressed in human leukemia cell lines
Virology, 303 (1), 164-73
DOI 10.1006/viro.2002.1615, PubMed 12482668 -
Effect of vaccination with mutant KRAS peptides on rat colon carcinogenesis induced by azoxymethane
Anticancer Res, 22 (1A), 171-5
PubMed 12017282 -
Clinical and cell line specific expression profiles of a human gene identified in experimental central nervous system metastases
Anticancer Res, 22 (4), 1949-57
PubMed 12174869 -
The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma
N Engl J Med, 346 (25), 1937-47
DOI 10.1056/NEJMoa012914, PubMed 12075054 -
mRNA-based electrotransfection of human dendritic cells and induction of cytotoxic T lymphocyte responses against the telomerase catalytic subunit (hTERT)
J Immunol Methods, 259 (1-2), 191-203
DOI 10.1016/s0022-1759(01)00506-3, PubMed 11730854 -
Identification of novel carrier peptides for the specific delivery of therapeutics into cancer cells
FASEB J, 17 (2), 256-8
DOI 10.1096/fj.02-0280fje, PubMed 12490548 -
How does autoimmunity cause tumor regression? A potential mechanism involving cross-reaction through epitope mimicry
Mol Med, 8 (3), 115-9
DOI 10.1007/BF03402004, PubMed 12142543 -
Combination of endostatin and a protein kinase Calpha DNA enzyme improves the survival of rats with malignant glioma
Neoplasia, 4 (6), 474-9
DOI 10.1038/sj.neo.7900271, PubMed 12407440 -
Inhibition of glycolipid shedding rescues recognition of a CD1+ T cell lymphoma by natural killer T (NKT) cells
Proc Natl Acad Sci U S A, 99 (12), 8197-202
DOI 10.1073/pnas.122636199, PubMed 12060764 -
The mouse enhancer element D6 directs Cre recombinase activity in the neocortex and the hippocampus
Mech Dev, 110 (1-2), 179-82
DOI 10.1016/s0925-4773(01)00597-4, PubMed 11744379 -
Expression of human protein tyrosine phosphatase epsilon in leucocytes: a potential ERK pathway-regulating phosphatase
Scand J Immunol, 56 (2), 195-203
DOI 10.1046/j.1365-3083.2002.01126.x, PubMed 12121439 -
Characterization, expression and functional aspects of a novel protein tyrosine phosphatase epsilon isoform
Scand J Immunol, 56 (3), 276-85
DOI 10.1046/j.1365-3083.2002.01127.x, PubMed 12193229 -
Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study
BMC Bioinformatics, 3, 36
DOI 10.1186/1471-2105-3-36, PubMed 12445336
Publications 2001
-
Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study
Br J Cancer, 85 (5), 692-6
DOI 10.1054/bjoc.2001.1964, PubMed 11531254 -
Automated constant denaturant capillary electrophoresis applied for detection of KRAS exon 1 mutations
Biotechniques, 30 (5), 972-5
DOI 10.2144/01305st01, PubMed 11355359 -
Mutation analysis of TP53 exons 5-8 by automated constant denaturant capillary electrophoresis
Tumour Biol, 22 (5), 323-7
DOI 10.1159/000050634, PubMed 11553863 -
High-dose therapy in patients with Hodgkin's disease: the use of selected CD34(+) cells is as safe as unmanipulated peripheral blood progenitor cells
Bone Marrow Transplant, 28 (9), 849-57
DOI 10.1038/sj.bmt.1703244, PubMed 11781645 -
Don't stop for repairs in a war zone: Darwinian evolution unites genes and environment in cancer development
Proc Natl Acad Sci U S A, 98 (10), 5379-81
DOI 10.1073/pnas.101137698, PubMed 11344279 -
Intradermal ras peptide vaccination with granulocyte-macrophage colony-stimulating factor as adjuvant: Clinical and immunological responses in patients with pancreatic adenocarcinoma
Int J Cancer, 92 (3), 441-50
DOI 10.1002/ijc.1205, PubMed 11291084 -
Antigen-specific IgG antibodies in stage IV long-time survival breast cancer patients
Mol Med, 7 (4), 230-9
DOI 10.1007/BF03401842, PubMed 11471567 -
Identification of immunogenic antigens using a phage-displayed cDNA library from an invasive ductal breast carcinoma tumour
Int J Oncol, 19 (6), 1303-9
DOI 10.3892/ijo.19.6.1303, PubMed 11713604 -
Occurrence of matrix metalloproteinases and tissue inhibitors of metalloproteinases in tuberculous pleuritis
Tuberculosis (Edinb), 81 (3), 203-9
DOI 10.1054/tube.2000.0276, PubMed 11466032 -
[Gene therapy in cancer]
Tidsskr Nor Laegeforen, 121 (4), 482-8
PubMed 11255868 -
Successful induction of immune responses against mutant ras in melanoma patients using intradermal injection of peptides and GM-CSF as adjuvant
Exp Dermatol, 10 (3), 161-7
DOI 10.1034/j.1600-0625.2001.010003161.x, PubMed 11380611 -
DNA enzyme targeting TNF-alpha mRNA improves hemodynamic performance in rats with postinfarction heart failure
Am J Physiol Heart Circ Physiol, 281 (5), H2211-7
DOI 10.1152/ajpheart.2001.281.5.H2211, PubMed 11668085 -
[Gene therapy--status and recommendations in Norwegian health care system]
Tidsskr Nor Laegeforen, 121 (3), 343-8
PubMed 11242880 -
Evidence for the involvement of Gi2 in activation of extracellular signal-regulated kinases in hepatocytes
BMC Cell Biol, 2, 13
DOI 10.1186/1471-2121-2-13, PubMed 11495629 -
A signal sequence trap based on cell enrichment using anti-CD19 antibody coated magnetic beads
Scand J Immunol, 54 (3), 280-4
DOI 10.1046/j.1365-3083.2001.00925.x, PubMed 11555391 -
Frameshift-mutation-derived peptides as tumor-specific antigens in inherited and spontaneous colorectal cancer
Proc Natl Acad Sci U S A, 98 (23), 13255-60
DOI 10.1073/pnas.231326898, PubMed 11687624 -
A TGF betaRII frameshift-mutation-derived CTL epitope recognised by HLA-A2-restricted CD8+ T cells
Cancer Immunol Immunother, 50 (9), 469-76
DOI 10.1007/s002620100222, PubMed 11761441 -
An anti-leukemic single chain Fv antibody selected from a synthetic human phage antibody library
Biochem Biophys Res Commun, 280 (2), 548-52
DOI 10.1006/bbrc.2000.4158, PubMed 11162553 -
Nucleic acid enzymes as a novel generation of anti-gene agents
Curr Mol Med, 1 (5), 575-88
DOI 10.2174/1566524013363366, PubMed 11899232 -
Profiling the immune response in patients with breast cancer by phage-displayed cDNA libraries
Eur J Immunol, 31 (3), 716-25
DOI 10.1002/1521-4141(200103)31:3<716::aid-immu716>3.0.co;2-9, PubMed 11241275 -
Loss of chromosome 11q21-23.1 and 17p and gain of chromosome 6p are independent prognostic indicators in B-cell non-Hodgkin's lymphoma
Br J Cancer, 85 (12), 1900-13
DOI 10.1054/bjoc.2001.2164, PubMed 11747333
Publications 2000
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Co-induction of Mad1 and c-Myc in activated normal B lymphocytes
Scand J Immunol, 51 (6), 565-70
DOI 10.1046/j.1365-3083.2000.00726.x, PubMed 10849366 -
Identification of nucleolar protein No55 as a tumour-associated autoantigen in patients with prostate cancer
Br J Cancer, 83 (6), 743-9
DOI 10.1054/bjoc.2000.1365, PubMed 10952778 -
Probing antinuclear antibody specificities by peptide phage display libraries
Clin Exp Rheumatol, 18 (4), 465-72
PubMed 10949721 -
Differential expression of bcl-2 homologs in human CD34(+) hematopoietic progenitor cells induced to differentiate into erythroid or granulocytic cells
Stem Cells, 18 (4), 261-72
DOI 10.1634/stemcells.18-4-261, PubMed 10924092 -
Protein kinase Calpha isoform regulates the activation of the MAP kinase ERK1/2 in human glioma cells: involvement in cell survival and gene expression
Mol Cell Biol Res Commun, 4 (2), 106-10
DOI 10.1006/mcbr.2000.0259, PubMed 11170840 -
Ephrin-B2 is a candidate ligand for the Eph receptor, EphB6
FEBS Lett, 466 (1), 169-74
DOI 10.1016/s0014-5793(99)01793-7, PubMed 10648835 -
Protein kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation of CD34(+) progenitor cells from human bone marrow
Blood, 95 (2), 510-8
DOI 10.1182/blood.V95.2.510, PubMed 10627456 -
cAMP-mediated growth inhibition of lymphoid cells in G1: rapid down-regulation of cyclin D3 at the level of translation
Eur J Immunol, 30 (6), 1757-68
DOI 10.1002/1521-4141(200006)30:6<1757::AID-IMMU1757>3.0.CO;2-N, PubMed 10898514 -
Sox-4 messenger RNA is expressed in the embryonic growth plate and regulated via the parathyroid hormone/parathyroid hormone-related protein receptor in osteoblast-like cells
J Bone Miner Res, 15 (12), 2402-12
DOI 10.1359/jbmr.2000.15.12.2402, PubMed 11127205 -
The C1orf9 gene encodes a putative transmembrane member of a novel protein family
Biochem Biophys Res Commun, 267 (3), 855-62
DOI 10.1006/bbrc.1999.2016, PubMed 10673381 -
Profiling the immune responses in patient sera with peptide and cDNA display libraries
Int J Mol Med, 6 (2), 123-8
DOI 10.3892/ijmm.6.2.123, PubMed 10891554 -
Design of nuclease resistant protein kinase calpha DNA enzymes with potential therapeutic application
J Mol Biol, 296 (3), 937-47
DOI 10.1006/jmbi.2000.3491, PubMed 10677293 -
Therapeutic RNA and DNA enzymes
Biochem Pharmacol, 60 (8), 1023-6
DOI 10.1016/s0006-2952(00)00395-6, PubMed 11007937 -
Oncogenic aberrations in the p53 pathway are associated with a high S phase fraction and poor patient survival in B-cell Non-Hodgkin's lymphoma
Int J Cancer, 89 (4), 313-24
DOI 10.1002/1097-0215(20000720)89:4<313::aid-ijc1>3.0.co;2-d, PubMed 10956404 -
A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes
Blood, 95 (1), 221-30
DOI 10.1182/blood.V95.1.221.001k01_221_230, PubMed 10607706