Publications

Publications published since 2000 from OUS - Department of Cancer Immunology

446 publications found

Publications 2022

  1. Meyer-Myklestad MH, Medhus AW, Stiksrud B, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Troseid M, Reikvam DH (2022)
    Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
    JAIDS, 89 (1), 77-86
    DOI 10.1097/QAI.0000000000002817
  2. Rye IH, Huse K, Josefsson SE, Kildal W, Danielsen HE, Schlichting E, Garred O, Riis ML, Lingjaerde OC, Myklebust JH, Russnes HG, OSBREAC (2022)
    Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
    Mol. Oncol., 16 (1), 88-103
    DOI 10.1002/1878-0261.13047

Publications 2021

  1. Ali M, Giannakopoulou E, Li YQ, Lehander M, Culleton SV, Yang WW, Knetter C, Odabasi MC, Bollineni RC, Yang XB, Foldvari Z, Boschen ML, Taraldsrud E, Stronen E, Toebes M, Hillen A, Mazzi S, de Ru AH, Janssen GMC, Kolstad A, Tjonnfjord GE, Lie BA, Griffioen M, Lehmann S, Osnes LT et al. (2021)
    T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
    Nat. Biotechnol.
    DOI 10.1038/s41587-021-01089-x
  2. Ask EH, Tschan-Plessl A, Gjerdingen TJ, Saetersmoen ML, Hoel HJ, Wiiger MT, Olweus J, Wahlin BE, Lingjaerde OC, Horowitz A, Cashen AF, Watkins M, Fehniger TA, Holte H, Kolstad A, Malmberg KJ (2021)
    A Systemic Protein Deviation Score Linked to PD-1(+) CD8(+) T Cell Expansion That Predicts Overall Survival in Diffuse Large B Cell Lymphoma
    Med, 2 (2), 180-+
    DOI 10.1016/j.medj.2020.10.006
  3. Bartolome-Casado R, Landsverk OJB, Chauhan SK, Saetre F, Hagen KT, Yaqub S, Oyen O, Horneland R, Aandahl EM, Aabakken L, Baekkevold ES, Jahnsen FL (2021)
    CD4(+)T cells persist for years in the human small intestine and display a T(H)1 cytokine profile
    Mucosal Immunol., 14 (2), 402-410
    DOI 10.1038/s41385-020-0315-5
  4. Chellappa S, Kushekhar K, Hagness M, Horneland R, Tasken K, Aandahl EM (2021)
    The Presence of Activated T Cell Subsets prior to Transplantation Is Associated with Increased Rejection Risk in Pancreas Transplant Recipients
    J. Immunol., 207 (10), 2501-2511
    DOI 10.4049/jimmunol.2001103
  5. Dillard P, Casey N, Pollmann S, Vernhoff P, Gaudernack G, Kvalheim G, Walchli S, Inderberg EM (2021)
    Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors
    OncoImmunology, 10 (1), 1936757
    DOI 10.1080/2162402X.2021.1936757
  6. Dillard P, Koksal H, Maggadottir SM, Winge-Main A, Pollmann S, Menard M, Myhre MR, Maelandsmo GM, Florenes VA, Gaudernack G, Kvalheim G, Walchli S, Inderberg EM (2021)
    Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
    Mol. Ther., 29 (3), 1199-1213
    DOI 10.1016/j.ymthe.2020.11.019
  7. Isaksen KT, Mastroianni MA, Rinde M, Rusten LS, Barzenje DA, Ramslien LF, Slaaen M, Jerm MB, Smeland EB, Rostoft S, Liestol K, Brodtkorb M, Holte H (2021)
    A simplified frailty score predicts survival and can aid treatment-intensity decisions in older patients with DLBCL
    Blood Adv., 5 (22), 4771-4782
    DOI 10.1182/bloodadvances.2021004777
  8. Jenum S, Tonby K, Rueegg CS, Ruhwald M, Kristiansen MP, Bang P, Olsen IC, Sellaeg K, Rostad K, Mustafa T, Tasken K, Kvale D, Mortensen R, Dyrhol-Riise AM (2021)
    A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
    Nat. Commun., 12 (1), 6774
    DOI 10.1038/s41467-021-27029-6
  9. Jiang XJ, Bergquist A, Loscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skanland SS, Maleki KT, Cornillet M, Tasken K, Franke A, Karlsen TH, Bjorkstrom NK, Melum E (2021)
    A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
    Sci. Transl. Med., 13 (582), eabb0036
    DOI 10.1126/scitranslmed.abb0036
  10. Jorgensen MJ, Nore KG, Aass HCD, Layre E, Nigou JM, Mortensen R, Tasken K, Kvale D, Jenum S, Tonby K, Dyrhol-Riise AM (2021)
    Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients
    Front. Cell. Infect. Microbiol., 11, 669623
    DOI 10.3389/fcimb.2021.669623
  11. Koksal H, Dillard P, Juzeniene A, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Walchli S (2021)
    Combinatorial CAR design improves target restriction
    J. Biol. Chem., 296, 100116
    DOI 10.1074/jbc.RA120.016234
  12. Lachota M, Lennikov A, Malmberg KJ, Zagozdzon R (2021)
    Bioinformatic Analysis Reveals Central Role for Tumor-Infiltrating Immune Cells in Uveal Melanoma Progression
    J Immunol. Res., 2021, 9920234
    DOI 10.1155/2021/9920234
  13. Langenbucher A, Bowen D, Sakhtemani R, Bournique E, Wise JF, Zou L, Bhagwat AS, Buisson R, Lawrence MS (2021)
    An extended APOBEC3A mutation signature in cancer
    Nat. Commun., 12 (1), 1602
    DOI 10.1038/s41467-021-21891-0
  14. Lone AM, Giansanti P, Jorgensen MJ, Gjerga E, Dugourd A, Scholten A, Saez-Rodriguez J, Heck AJR, Tasken K (2021)
    Systems approach reveals distinct and shared signaling networks of the four PGE(2) receptors in T cells
    Sci. Signal., 14 (703), eabc8579
    DOI 10.1126/scisignal.abc8579
  15. Lone AM, Tasken K (2021)
    Phosphoproteomics-Based Characterization of Prostaglandin E-2 Signaling in T Cells
    Mol. Pharmacol., 99 (5), 370-382
    DOI 10.1124/molpharm.120.000170
  16. Lorvik KB, Meyer-Myklestad MH, Kushekar K, Handeland C, Medhus AW, Lund-Iversen M, Stiksrud B, Kvale D, Dyrhol-Riise AM, Tasken K, Reikvam DH (2021)
    Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4(+) T Cells in HIV-Infected Immunological Non-Responders
    Front. Immunol., 12, 744155
    DOI 10.3389/fimmu.2021.744155
  17. Maclachlan KH, Rustad EH, Derkach A, Zheng-Lin BB, Yellapantula V, Diamond B, Hultcrantz M, Ziccheddu B, Boyle EM, Blaney P, Bolli N, Zhang YM, Dogan A, Lesokhin AM, Morgan GJ, Landgren O, Maura F (2021)
    Copy number signatures predict chromothripsis and clinical outcomes in newly diagnosed multiple myeloma
    Nat. Commun., 12 (1), 5172
    DOI 10.1038/s41467-021-25469-8
  18. Mazzarella L, Enblad G, Olweus J, Malmberg KJ, Jerkeman M (2021)
    Advances in immune therapies in hematological malignancies
    J. Intern. Med.
    DOI 10.1111/joim.13395
  19. Melvold K, Giliberto M, Karlsen L, Ayuda-Duran P, Hanes R, Holien T, Enserink J, Brown JR, Tjonnfjord GE, Tasken K, Skanland SS (2021)
    Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
    Mol. Oncol.
    DOI 10.1002/1878-0261.13153
  20. Mensali N, Dillard P, Fayzullin A, Koksal H, Gaudernack G, Kvalheim G, Inderberg EM, Walchli S (2021)
    "Built-in" PD-1 blocker to rescue NK-92 activity from PD-L1-mediated tumor escape mechanisms
    Faseb J., 35 (9), e21750
    DOI 10.1096/fj.202100025R
  21. Mester S, Evers M, Meyer S, Nilsen J, Greiff V, Sandlie I, Leusen J, Andersen JT (2021)
    Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo
    mAbs, 13 (1), 1893888
    DOI 10.1080/19420862.2021.1893888
  22. Oksvold MP, Berglund UW, Gad H, Bai BY, Stokke T, Rein ID, Pham T, Sanjiv K, Oy GF, Norum JH, Smeland EB, Myklebust JH, Helleday T, Vatsveen TK (2021)
    Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
    Sci Rep, 11 (1), 6317
    DOI 10.1038/s41598-021-85613-8
  23. Roeker LE, Eyre TA, Thompson MC, Lamanna N, Coltoff AR, Davids MS, Baker PO, Leslie L, Rogers KA, Allan JN, Cordoba R, Lopez-Garcia A, Antic D, Pagel JM, Martinez-Calle N, Garcia-Moarco JA, Hernandez-Rivas JA, Miras F, Coombs CC, Osterborg A, Hansson L, Seddon AN, Jimenez JL, Wilson MR, El-Sharkawi D et al. (2021)
    COVID-19 in patients with CLL: improved survival outcomes and update on management strategies
    Blood, 138 (18), 1768-+
    DOI 10.1182/blood.2021011841
  24. Rustad EH, Nadeu F, Angelopoulos N, Ziccheddu B, Bolli N, Puente XS, Campo E, Landgren O, Maura F (2021)
    mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies
    Commun. Biol., 4 (1), 424
    DOI 10.1038/s42003-021-01938-0
  25. Sanjiv K, Calderon-Montano JM, Pham TM, Erkers T, Tsuber V, Almlof I, Hoglund A, Heshmati Y, Seashore-Ludlow B, Danda AN, Gad H, Wiita E, Gokturk C, Rasti A, Friedrich S, Centio A, Estruch M, Vatsveen TK, Struyf N, Visnes T, Scobie M, Koolmeister T, Henriksson M, Wallner O, Sandvall T et al. (2021)
    MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia
    Cancer Res., 81 (22), 5733-5744
    DOI 10.1158/0008-5472.CAN-21-0061
  26. Sioud M (2021)
    Reducing the immunosuppressive tumor microenvironment enhances photoimmunotherapy efficacy Comment
    EBioMedicine, 67, 103351
    DOI 10.1016/j.ebiom.2021.103351
  27. Sioud M, Juzenas P, Zhang QD, Kleinauskas A, Peng Q (2021)
    Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Cell Monolayer and Multicellular Tumor Spheroid Models
    Cancers, 13 (13), 3356
    DOI 10.3390/cancers13133356
  28. Sioud M, Juzenas P, Zhang QD, Kleinauskas A, Peng Q (2021)
    Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Monolayer and Multicellular Tumor Spheroid Models (vol 13, 3356, 2021)
    Cancers, 13 (21), 5513
    DOI 10.3390/cancers13215513
  29. Skanland SS, Mato AR (2021)
    Overcoming resistance to targeted therapies in chronic lymphocytic leukemia
    Blood Adv., 5 (1), 334-343
    DOI 10.1182/bloodadvances.2020003423
  30. Spasevska I, Myklebust JH (2021)
    What It Takes to Transform a T Cell
    Cancer Res., 81 (12), 3160-3161
    DOI 10.1158/0008-5472.CAN-21-0784
  31. Steen CB, Luca BA, Esfahani MS, Azizi A, Sworder BJ, Nabet BY, Kurtz DM, Liu CL, Khameneh F, Advani RH, Natkunam Y, Myklebust JH, Diehn M, Gentles AJ, Newman AM, Alizadeh AA (2021)
    The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma
    Cancer Cell, 39 (10), 1422-+
    DOI 10.1016/j.ccell.2021.08.011
  32. Sullivan LC, Nguyen THO, Harpur CM, Stankovic S, Kanagarajah AR, Koutsakos M, Saunders PM, Cai ZY, Gray JA, Widjaja JML, Lin J, Pietra G, Mingari MC, Moretta L, Samir J, Luciani F, Westall GP, Malmberg KJ, Kedzierska K, Brooks AG (2021)
    Natural killer cell receptors regulate responses of HLA-E-restricted T cells
    Sci. Immunol., 6 (58), eabe9057
    DOI 10.1126/sciimmunol.abe9057
  33. Szodoray P, Andersen TK, Heinzelbecker J, Imbery JF, Huszthy PC, Stanford SM, Bogen B, Landsverk OB, Bottini N, Tveita A, Munthe LA, Nakken B (2021)
    Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity
    Cell Reports, 36 (6), 109525
    DOI 10.1016/j.celrep.2021.109525
  34. Tschan-Plessl A, Kalberer CP, Wieboldt R, Stern M, Siegler U, Wodnar-Filipowicz A, Gerull S, Halter J, Heim D, Tichelli A, Tsakiris DA, Malmberg KJ, Passweg JR, Bottos A (2021)
    Cellular immunotherapy with multiple infusions of in vitro-expanded haploidentical natural killer cells after autologous transplantation for patients with plasma cell myeloma
    Cytotherapy, 23 (4), 329-338
    DOI 10.1016/j.jcyt.2020.09.009
  35. Woan KV, Kim H, Bjordahl R, Davis ZB, Gaidarova S, Goulding J, Hancock B, Mahmood S, Abujarour R, Wang HB, Tuininga K, Zhang B, Wu CY, Kodal B, Khaw M, Bendzick L, Rogers P, Ge MQ, Bonello G, Meza M, Felices M, Huffman J, Dailey T, Lee TT, Walcheck B et al. (2021)
    Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
    Cell Stem Cell, 28 (12), 2062-+
    DOI 10.1016/j.stem.2021.08.013
  36. Yaqub S, Bjornbeth BA, Angelsen JH, Fristrup CW, Gronbech JE, Hemmingsson O, Isaksson B, Juel IS, Larsen PN, Lindell G, Mortensen FV, Mortensen KE, Rizell M, Sandstrom P, Sandvik OM, Sparrelid E, Taflin H, Tasken K, ASAC Study grp (2021)
    Aspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial
    Trials, 22 (1), 642
    DOI 10.1186/s13063-021-05587-w

Publications 2020

  1. Bartok O, Pataskar A, Nagel R, Laos M, Goldfarb E, Hayoun D, Levy R, Korner PR, Kreuger IZM, Champagne J, Zaal EA, Bleijerveld OB, Huang XY, Kenski J, Wargo J, Brandis A, Levin Y, Mizrahi O, Alon M, Lebon S, Yang WW, Nielsen MM, Stern-Ginossar N, Altelaar M, Berkers CR et al. (2020)
    Anti-tumour immunity induces aberrant peptide presentation in melanoma
    Nature
    DOI 10.1038/s41586-020-03054-1
  2. Caglayan S, Hashim A, Cieslar-Pobuda A, Jensen V, Behringer S, Talug B, Chu DT, Pecquet C, Rogne M, Brech A, Brorson SH, Nagelhus EA, Hannibal L, Boschi A, Tasken K, Staerk J (2020)
    Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
    iScience, 23 (6), 101154
    DOI 10.1016/j.isci.2020.101154
  3. Chu DT, Phuong TNT, Tien NLB, Tran DK, Van Thanh V, Quang TL, Truong DT, Pham VH, Ngoc VTN, Chu-Dinh T, Kushekhar K (2020)
    An Update on the Progress of Isolation, Culture, Storage, and Clinical Application of Human Bone Marrow Mesenchymal Stem/Stromal Cells
    Int. J. Mol. Sci., 21 (3), 708
    DOI 10.3390/ijms21030708
  4. Clement D, Goodridge JP, Grimm C, Patel S, Malmberg KJ (2020)
    TRP Channels as Interior Designers: Remodeling the Endolysosomal Compartment in Natural Killer Cells
    Front. Immunol., 11, 753
    DOI 10.3389/fimmu.2020.00753
  5. Darvekar S, Juzenas P, Oksvold M, Kleinauskas A, Holien T, Christensen E, Stokke T, Sioud M, Peng Q (2020)
    Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis
    Cancers, 12 (2), 377
    DOI 10.3390/cancers12020377
  6. Evers M, Ten Broeke T, Jansen JHM, Nederend M, Hamdan F, Reiding KR, Meyer S, Moerer P, Brinkman I, Rosner T, Lebbink RJ, Valerius T, Leusen JHW (2020)
    Novel chimerized IgA CD20 antibodies: Improving neutrophil activation against CD20-positive malignancies
    mAbs, 12 (1), 1795505
    DOI 10.1080/19420862.2020.1795505
  7. Geier CB, Farmer JR, Foldvari Z, Ujhazi B, Steininger J, Sleasman JW, Parikh S, Dilley MA, Pai SY, Henderson L, Hazen M, Neven B, Moshous D, Sharapova SO, Mihailova S, Yankova P, Naumova E, Ozen S, Byram K, Fernandez J, Wolf HM, Eibl MM, Notarangelo LD, Calabrese LH, Walter JE (2020)
    Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency
    Front. Immunol., 11, 574738
    DOI 10.3389/fimmu.2020.574738
  8. Goldenson BH, Zhu H, Wang YM, Heragu N, Bernareggi D, Ruiz-Cisneros A, Bahena A, Ask EH, Hoel HJ, Malmberg KJ, Kaufman DS (2020)
    Umbilical Cord Blood and iPSC-Derived Natural Killer Cells Demonstrate Key Differences in Cytotoxic Activity and KIR Profiles
    Front. Immunol., 11, 561553
    DOI 10.3389/fimmu.2020.561553
  9. Jacobs B, Schlogl S, Strobl CD, Volkl S, Stoll A, Mougiakakos D, Malmberg KJ, Mackensen A, Aigner M (2020)
    The Oncometabolite 5 '-Deoxy-5 '-Methylthioadenosine Blocks Multiple Signaling Pathways of NK Cell Activation
    Front. Immunol., 11, 2128
    DOI 10.3389/fimmu.2020.02128
  10. Jakobsen LH, Ellin F, Smeland KB, Wasterlid T, Christensen JH, Jorgensen JM, Josefsson PL, Ovlisen AK, Holte H, Blaker YN, Grauslund JH, Bjorn J, Molin D, Lagerlof I, Smedby KE, Colvin K, Thanarajasingam G, Maurer MJ, Habermann TM, Song KW, Zhu KY, Gerrie AS, Cheah CY, El-Galaly TC (2020)
    Minimal relapse risk and early normalization of survival for patients with Burkitt lymphoma treated with intensive immunochemotherapy: an international study of 264 real-world patients
    Br. J. Haematol., 189 (4), 661-671
    DOI 10.1111/bjh.16425
  11. Kuttner S, Wickstrom KK, Kalda G, Dorraji SE, Martin-Armas M, Oteiza A, Jenssen R, Fenton K, Sundset R, Axelsson J (2020)
    Machine learning derived input-function in a dynamic F-18-FDG PET study of mice
    Biomed. Phys. Eng. Express, 6 (1), 015020
    DOI 10.1088/2057-1976/ab6496
  12. Kyte JA, Andresen NK, Russnes HG, Fretland SO, Falk RS, Lingjaerde OC, Naume B (2020)
    ICON: a randomized phase IIb study evaluating immunogenic chemotherapy combined with ipilimumab and nivolumab in patients with metastatic hormone receptor positive breast cancer
    J. Transl. Med., 18 (1), 269
    DOI 10.1186/s12967-020-02421-w
  13. Kyte JA, Rossevold A, Falk RS, Naume B (2020)
    ALICE: a randomized placebo-controlled phase II study evaluating atezolizumab combined with immunogenic chemotherapy in patients with metastatic triple-negative breast cancer
    J. Transl. Med., 18 (1), 252
    DOI 10.1186/s12967-020-02424-7
  14. Lachota M, Vincenti M, Winiarska M, Boye K, Zagozdzon R, Malmberg KJ (2020)
    Prospects for NK Cell Therapy of Sarcoma
    Cancers, 12 (12), 3719
    DOI 10.3390/cancers12123719
  15. Majzner RG, Rietberg SP, Sotillo E, Dong R, Vachharajani VT, Labanieh L, Myklebust JH, Kadapakkam M, Weber EW, Tousley AM, Richards RM, Heitzeneder S, Nguyen SM, Wiebking V, Theruvath J, Lynn RC, Xu P, Dunn AR, Vale RD, Mackall CL (2020)
    Tuning the Antigen Density Requirement for CAR T-cell Activity
    Cancer Discov., 10 (5), 702-723
    DOI 10.1158/2159-8290.CD-19-0945
  16. Mato AR, Roeker LE, Lamanna N, Allan JN, Leslie L, Pagel JM, Patel K, Osterborg A, Wojenski D, Kamdar M, Huntington SF, Davids MS, Brown JR, Antic D, Jacobs R, Ahn IE, Pu J, Isaac KM, Barr PM, Ujjani CS, Geyer MB, Berman E, Zelenetz AD, Malakhov N, Furman RR et al. (2020)
    Outcomes of COVID-19 in patients with CLL: a multicenter international experience
    Blood, 136 (10), 1134-1143
    DOI 10.1182/blood.2020006965
  17. Maucourant C, Filipovic I, Ponzetta A, Aleman S, Cornillet M, Hertwig L, Strunz B, Lentini A, Reinius B, Brownlie D, Cuapio A, Ask EH, Hull RM, Haroun-Izquierdo A, Schaffer M, Klingstrom J, Folkesson E, Buggert M, Sandberg JK, Eriksson LI, Rooyackers O, Ljunggren HG, Malmberg KJ, Michaelsson J, Marquardt N et al. (2020)
    Natural killer cell immunotypes related to COVID-19 disease severity
    Sci. Immunol., 5 (50), eabd6832
    DOI 10.1126/sciimmunol.abd6832
  18. Meas HZ, Haug M, Beckwith MS, Louet C, Ryan L, Hu ZY, Landskron J, Nordbo SA, Tasken K, Yin H, Damas JK, Flo TH (2020)
    Sensing of HIV-1 by TLR8 activates human T cells and reverses latency
    Nat. Commun., 11 (1), 147
    DOI 10.1038/s41467-019-13837-4
  19. Mensali N, Myhre MR, Dillard P, Pollmann S, Gaudernack G, Kvalheim G, Walchli S, Inderberg EM (2020)
    Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy (vol 68, pg 1235, 2019)
    Cancer Immunol. Immunother., 69 (1), 159-161
    DOI 10.1007/s00262-019-02409-6
  20. Patel S, Malmberg KJ (2020)
    Preventing a shock to the system. Two-pore channel 1 negatively regulates anaphylaxis
    Cell Calcium, 92, 102289
    DOI 10.1016/j.ceca.2020.102289
  21. Pfefferle A, Jacobs B, Haroun-Izquierdo A, Kveberg L, Sohlberg E, Malmberg KJ (2020)
    Deciphering Natural Killer Cell Homeostasis
    Front. Immunol., 11, 812
    DOI 10.3389/fimmu.2020.00812
  22. Rein ID, Noto HO, Bostad M, Huse K, Stokke T (2020)
    Cell Cycle Analysis and Relevance for Single-Cell Gating in Mass Cytometry
    Cytom. Part A, 97 (8), 832-844
    DOI 10.1002/cyto.a.23960
  23. Sioud M (2020)
    Microbial sensing by haematopoietic stem and progenitor cells: Vigilance against infections and immune education of myeloid cells
    Scand. J. Immunol., 92 (5), e12957
    DOI 10.1111/sji.12957
  24. Skanland SS, Cremaschi A, Bendiksen H, Hermansen JU, Raj DBTG, Munthe LA, Tjonnfjord GE, Tasken K (2020)
    An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL
    Leukemia, 34 (2), 478-487
    DOI 10.1038/s41375-019-0569-7
  25. Skanland SS, Karlsen L, Tasken K (2020)
    B cell signalling pathways-New targets for precision medicine in chronic lymphocytic leukaemia
    Scand. J. Immunol., 92 (5), e12931
    DOI 10.1111/sji.12931
  26. Sonnet F, Namork E, Stylianou E, Gaare-Olstad I, Huse K, Andorf S, Mjaaland S, Dirven H, Nygaard U (2020)
    Reduced polyfunctional T cells and increased cellular activation markers in adult allergy patients reporting adverse reactions to food
    BMC Immunol., 21 (1), 43
    DOI 10.1186/s12865-020-00373-w
  27. Wise JF, Nakken S, Steen CB, Vodak D, Troen G, Johannessen B, Lingjxrde OC, Hilden V, Blaker YN, Bai BY, Aasheim LB, Pasanen A, Lorenz S, Sveen A, Lothe RA, Myklebost O, Leppa S, Meza-Zepeda LA, Beiske K, Lawrence MS, Hovig E, Myklebust JH, Smeland EB, Holte H (2020)
    Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
    Blood Adv., 4 (9), 1859-1866
    DOI 10.1182/bloodadvances.2019001325
  28. Zhu H, Blum RH, Bernareggi D, Ask EH, Wu ZM, Hoel HJ, Meng ZP, Wu CS, Guan KL, Malmberg KJ, Kaufman DS (2020)
    Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity
    Cell Stem Cell, 27 (2), 224-+
    DOI 10.1016/j.stem.2020.05.008

Publications 2019

  1. Ali M, Foldvari Z, Giannakopoulou E, Boschen ML, Stronen E, Yang WW, Toebes M, Schubert B, Kohlbacher O, Schumacher TN, Olweus J (2019)
    Induction of neoantigen-reactive T cells from healthy donors
    Nat. Protoc., 14 (6), 1926-1943
    DOI 10.1038/s41596-019-0170-6
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    EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
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    The PI3K p110 delta Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
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  5. Cornillet M, Jansson H, Schaffer M, Hertwig L, Berglin L, Zimmer CL, Johansson H, Ellis E, Isaksson B, Gonzalez-Galarza FF, Middleton D, Malmberg KJ, Sparrelid E, Bjorkstrom NK (2019)
    Imbalance of Genes Encoding Natural Killer Immunoglobulin-Like Receptors and Human Leukocyte Antigen in Patients With Biliary Cancer
    Gastroenterology, 157 (4), 1067-+
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    Hierarchical Normalized Completely Random Measures for Robust Graphical Modeling
    Bayesian Anal., 14 (4), 1271-1301
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  7. Enqvist M, Jacobs B, Junlen HR, Schaffer M, Melen CM, Friberg D, Wahlin BE, Malmberg KJ (2019)
    Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma
    Front. Immunol., 10, 2085
    DOI 10.3389/fimmu.2019.02085
  8. Farmer JR, Foldvari Z, Ujhazi B, De Ravin SS, Chen K, Bleesing JJH, Schuetz C, Al-Herz W, Abraham RS, Joshi AY, Costa-Carvalho BT, Buchbinder D, Booth C, Reiff A, Ferguson PJ, Aghamohammadi A, Abolhassani H, Puck JM, Adeli M, Cancrini C, Palma P, Bertaina A, Locatelli F, Di Matteo G, Geha RS et al. (2019)
    Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency
    J. Allergy Clin. Immunol.-Pract., 7 (6), 1970-+
    DOI 10.1016/j.jaip.2019.02.038
  9. Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjallquist U, Linnarsson S, Patel S, Tasken K, Stenmark H, Malmberg KJ (2019)
    Remodeling of secretory lysosomes during education tunes functional potential in NK cells
    Nat. Commun., 10, 514
    DOI 10.1038/s41467-019-08384-x
  10. Huse K (2019)
    Expanding the Clinical Cytometry Toolbox-Receptor Occupancy by Mass Cytometry
    Cytom. Part A, 95 (10), 1046-1048
    DOI 10.1002/cyto.a.23784
  11. Huse K, Wogsland CE, Polikowsky HG, Diggins KE, Smeland EB, Myklebust JH, Irish JM (2019)
    Human Germinal Center B Cells Differ from Naive and Memory B Cells in CD40 Expression and CD40L-Induced Signaling Response
    Cytom. Part A, 95A (4), 442-449
    DOI 10.1002/cyto.a.23737
  12. Jacobs B, Pfefferle A, Clement D, Berg-Larsen A, Saetersmoen ML, Lorenz S, Wiiger MT, Goodridge JP, Malmberg KJ (2019)
    Induction of the BIM Short Splice Variant Sensitizes Proliferating NK Cells to IL-15 Withdrawal
    J. Immunol., 202 (3), 736-746
    DOI 10.4049/jimmunol.1801146
  13. Josefsson SE, Beiske K, Blaker YN, Forsund MS, Holte H, Ostenstad B, Kimby E, Koksal H, Walchli S, Bai BY, Smeland EB, Levy R, Kolstad A, Huse K, Myklebust JH (2019)
    TIGIT and PD-1 Mark Intratumoral T Cells with Reduced Effector Function in B-cell Non-Hodgkin Lymphoma
    Cancer Immunol. Res., 7 (3), 355-362
    DOI 10.1158/2326-6066.CIR-18-0351
  14. Koksal H, Dillard P, Josefsson SE, Maggadottir SM, Pollmann S, Fane A, Blaker YN, Beiske K, Huse K, Kolstad A, Holte H, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Walchli S (2019)
    Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma
    Blood Adv., 3 (8), 1230-1243
    DOI 10.1182/bloodadvances.2018029678
  15. Kyte JA, Fane A, Pule M, Gaudernack G (2019)
    Transient redirection of T cells for adoptive cell therapy with telomerase-specific T helper cell receptors isolated from long term survivors after cancer vaccination
    OncoImmunology, 8 (4), e1565236
    DOI 10.1080/2162402X.2019.1565236
  16. Mensali N, Dillard P, Hebeisen M, Lorenz S, Theodossiou T, Myhre MR, Fane A, Gaudernack G, Kvalheim G, Myklebust JH, Inderberg EM, Walchli S (2019)
    NK cells specifically TCR-dressed to kill cancer cells
    EBioMedicine, 40, 106-117
    DOI 10.1016/j.ebiom.2019.01.031
  17. Mensali N, Grenov A, Pati NB, Dillard P, Myhre MR, Gaudernack G, Kvalheim G, Inderberg EM, Bakke O, Walchli S (2019)
    Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity
    OncoImmunology, 8 (3), e1558663
    DOI 10.1080/2162402X.2018.1558663
  18. Mensali N, Myhre MR, Dillard P, Pollmann S, Gaudernack G, Kvalheim G, Walchli S, Inderberg EM (2019)
    Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
    Cancer Immunol. Immunother., 68 (8), 1235-1243
    DOI 10.1007/s00262-019-02356-2
  19. Olweus J, Lund-Johansen F (2019)
    Finding Neo (antigens, that is)
    Blood, 134 (2), 108-109
    DOI 10.1182/blood.2019001334
  20. Pfefferle A, Jacobs B, Netskar H, Ask EH, Lorenz S, Clancy T, Goodridge JP, Sohlberg E, Malmberg KJ (2019)
    Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity
    Cell Reports, 29 (8), 2284-+
    DOI 10.1016/j.celrep.2019.10.058
  21. Saetersmoen ML, Hammer Q, Valamehr B, Kaufman DS, Malmberg KJ (2019)
    Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells
    Semin. Immunopathol., 41 (1), 59-68
    DOI 10.1007/s00281-018-0721-x
  22. Sioud M (2019)
    Phage Display Libraries: From Binders to Targeted Drug Delivery and Human Therapeutics
    Mol. Biotechnol., 61 (4), 286-303
    DOI 10.1007/s12033-019-00156-8
  23. Sioud M (2019)
    Releasing the Immune System Brakes Using siRNAs Enhances Cancer Immunotherapy
    Cancers, 11 (2), 176
    DOI 10.3390/cancers11020176
  24. Sioud M, Pettersen S, Ailte I, Floisand Y (2019)
    Targeted Killing of Monocytes/Macrophages and Myeloid Leukemia Cells with Pro-Apoptotic Peptides
    Cancers, 11 (8), 1088
    DOI 10.3390/cancers11081088
  25. Skanland SS, Cieslar-Pobuda A (2019)
    Off-label uses of drugs for depression
    Eur. J. Pharmacol., 865, 172732
    DOI 10.1016/j.ejphar.2019.172732
  26. Skanland SS, Tasken K (2019)
    Carboxyl-Terminal Src Kinase Binds CD28 upon Activation and Mutes Downstream Signaling
    J. Immunol., 203 (4), 1055-1063
    DOI 10.4049/jimmunol.1801660
  27. Steen CB, Leich E, Myklebust JH, Lockmer S, Wise JF, Wahlin BE, Ostenstad B, Liestol K, Kimby E, Rosenwald A, Smeland EB, Holte H, Lingjaerde OC, Brodtkorb M (2019)
    A clinico-molecular predictor identifies follicular lymphoma patients at risk of early transformation after first-line immunotherapy
    Haematologica, 104 (10), E460-E464
    DOI 10.3324/haematol.2018.209080
  28. Stiksrud B, Aass HCD, Lorvik KB, Ueland T, Troseid M, Dyrhol-Riise AM (2019)
    Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4(+) recovery
    Aids, 33 (7), 1117-1129
    DOI 10.1097/QAD.0000000000002173
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    FOXK1 and FOXK2 regulate aerobic glycolysis
    Nature, 566 (7743), 279-+
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    An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
    Nat. Commun., 10, 5499
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    Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
    npj Breast Cancer, 5, 13
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    Genomes captured during tumour spread
    Nature, 575 (7781), 60-61
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Publications 2018

  1. Bidard FC, Michiels S, Riethdorf S, Mueller V, Esserman LJ, Lucci A, Naume B, Horiguchi J, Gisbert-Criado R, Sleijfer S, Toi M, Garcia-Saenz JA, Hartkopf A, Generali D, Rothe F, Smerage J, Muinelo-Romay L, Stebbing J, Viens P, Magbanua MJM, Hall CS, Engebraaten O, Takata D, Vidal-Martinez J, Onstenk W et al. (2018)
    Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-analysis
    JNCI-J. Natl. Cancer Inst., 110 (6), djy018-567
    DOI 10.1093/jnci/djy018
  2. Bjorklund AT, Carlsten M, Sohlberg E, Liu LL, Clancy T, Karimi M, Cooley S, Miller JS, Klimkowska M, Schaffer M, Watz E, Wikstrom K, Blomberg P, Wahlin BE, Palma M, Hansson L, Ljungman P, Hellstrom-Lindberg E, Ljunggren HG, Malmberg KJ (2018)
    Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML
    Clin. Cancer Res., 24 (8), 1834-1844
    DOI 10.1158/1078-0432.CCR-17-3196
  3. De Santis F, Del Vecchio M, Castagnoli L, De Braud F, Di Cosimo S, Franceschini D, Fuca G, Hiscott J, Malmberg KJ, McGranahan N, Pietrantonio F, Rivoltini L, Sangaletti S, Tagliabue E, Tripodo C, Vernieri C, Zitvogel L, Pupa SM, Di Nicola M (2018)
    Innovative therapy, monoclonal antibodies, and beyond: Highlights from the eighth annual meeting
    Cytokine Growth Factor Rev., 44, 1-10
    DOI 10.1016/j.cytogfr.2018.10.005
  4. Dukic AR, Gerbaud P, Guibourdenche J, Thiede B, Tasken K, Pidoux G (2018)
    Ezrin-anchored PKA phosphorylates serine 369 and 373 on connexin 43 to enhance gap junction assembly, communication, and cell fusion
    Biochem. J., 475, 455-476
    DOI 10.1042/BCJ20170529
  5. Eide HA, Knudtsen IS, Sandhu V, Londalen AM, Halvorsen AR, Abravan A, Kure EH, Bogsrud TV, Brustugun OT, Kyte JA, Malinen E, Helland A (2018)
    Serum cytokine profiles and metabolic tumor burden in patients with non-small cell lung cancer undergoing palliative thoracic radiation therapy
    Adv. Radiat. Oncol., 3 (2), 130-138
    DOI 10.1016/j.adro.2017.12.007
  6. Hermansen JU, Tjonnfjord GE, Munthe LA, Tasken K, Skanland SS (2018)
    Cryopreservation of primary B cells minimally influences their signaling responses
    Sci Rep, 8, 17651
    DOI 10.1038/s41598-018-36121-9
  7. Holte H, Beiske K, Boyle M, Troen G, Blaker YN, Myklebust J, Kvaloy S, Rosenwald A, Lingjaerde OC, Rimsza LM, Smeland EB, Scott DW, Kolstad A (2018)
    The MCL35 gene expression proliferation assay predicts high-risk MCL patients in a Norwegian cohort of younger patients given intensive first line therapy
    Br. J. Haematol., 183 (2), 225-234
    DOI 10.1111/bjh.15518
  8. Inderberg EM, Mensali N, Oksvold MP, Fallang LE, Fane A, Skorstad G, Stenvik GE, Progida C, Bakke O, Kvalheim G, Myklebust JH, Walchli S (2018)
    Human c-SRC kinase (CSK) overexpression makes T cells dummy
    Cancer Immunol. Immunother., 67 (4), 525-536
    DOI 10.1007/s00262-017-2105-9
  9. Josefsson SE, Huse K, Kolstad A, Beiske K, Pende D, Steen CB, Inderberg EM, Lingjaerde OC, Ostenstad B, Smeland EB, Levy R, Irish JM, Myklebust JH (2018)
    T Cells Expressing Checkpoint Receptor TIGIT Are Enriched in Follicular Lymphoma Tumors and Characterized by Reversible Suppression of T-cell Receptor Signaling
    Clin. Cancer Res., 24 (4), 870-881
    DOI 10.1158/1078-0432.CCR-17-2337
  10. Lawless D, Geier CB, Farmer JR, Allen HL, Thwaites D, Atschekzei F, Brown M, Buchbinder D, Burns SO, Butte MJ, Csomos K, Deevi SVV, Egner W, Ehl S, Eibl MM, Fadugba O, Foldvari Z, Green DM, Henrickson SE, Holland SM, John T, Klemann C, Kuijpers TW, Moreira F, Piller A et al. (2018)
    Prevalence and clinical challenges among adults with primary immunodeficiency and recombination-activating gene deficiency
    J. Allergy Clin. Immunol., 141 (6), 2303-2306
    DOI 10.1016/j.jaci.2018.02.007
  11. Mottok A, Wright G, Rosenwald A, Ott G, Ramsower C, Campo E, Braziel RM, Delabie J, Weisenburger DD, Song JY, Chan WC, Cook JR, Fu K, Greiner T, Smeland E, Holte H, Savage KJ, Glinsmann-Gibson BJ, Gascoyne RD, Staudt LM, Jaffe ES, Connors JM, Scott DW, Steidl C, Rimsza LM (2018)
    Molecular classification of primary mediastinal large B-cell lymphoma using routinely available tissue specimens
    Blood, 132 (22), 2401-2405
    DOI 10.1182/blood-2018-05-851154
  12. Oei VYS, Siernicka M, Graczyk-Jarzynka A, Hoel HJ, Yang WW, Palacios D, Almasbak H, Bajor M, Clement D, Brandt L, Onfelt B, Goodridge J, Winiarska M, Zagozdzon R, Olweus J, Kyte JA, Malmberg KJ (2018)
    Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors
    Cancer Immunol. Res., 6 (4), 467-480
    DOI 10.1158/2326-6066.CIR-17-0207
  13. Peng W, de Bruijn HS, Farrell E, Sioud M, Mashayekhi V, Oliveira S, van Dam GM, Roodenburg JLN, Witjes MJH, Robinson DJ (2018)
    Epidermal growth factor receptor (EGFR) density may not be the only determinant for the efficacy of EGFR-targeted photoimmunotherapy in human head and neck cancer cell lines
    Lasers Surg. Med., 50 (5), 513-522
    DOI 10.1002/lsm.22930
  14. Rogne M, Chu DT, Kuntziger TM, Mylonakou MN, Collas P, Tasken K (2018)
    OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells
    Mol. Biol. Cell, 29 (12), 1487-1501
    DOI 10.1091/mbc.E17-09-0538
  15. Schwab C, Gabrysch A, Olbrich P, Patino V, Warnatz K, Wolff D, Hoshino A, Kobayashi M, Imai K, Takagi M, Dybedal I, Haddock JA, Sansom DM, Lucena JM, Seidl M, Schmitt-Graeff A, Reiser V, Emmerich F, Frede N, Bulashevska A, Salzer U, Schubert D, Hayakawa S, Okada S, Kanariou M et al. (2018)
    Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects
    J. Allergy Clin. Immunol., 142 (6), 1932-1946
    DOI 10.1016/j.jaci.2018.02.055
  16. Sioud M (2018)
    T-cell cross-reactivity may explain the large variation in how cancer patients respond to checkpoint inhibitors
    Scand. J. Immunol., 87 (3), e12643
    DOI 10.1111/sji.12643
  17. Sioud M, Westby P, Vasovic V, Floisand Y, Peng Q (2018)
    Development of a new high-affinity human antibody with antitumor activity against solid and blood malignancies
    Faseb J., 32 (9), 5063-5077
    DOI 10.1096/fj.201701544R
  18. Tutturen AEV, Dorum S, Clancy T, Reims HM, Christophersen A, Lundin KEA, Sollid LM, de Souza GA, Stamnaes J (2018)
    Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry
    Am. J. Pathol., 188 (7), 1563-1579
    DOI 10.1016/j.ajpath.2018.03.017
  19. Vatsveen TK, Myhre MR, Steen CB, Walchli S, Lingjaerde OC, Bai BY, Dillard P, Theodossiou TA, Holien T, Sundan A, Inderberg EM, Smeland EB, Myklebust JH, Oksvold MP (2018)
    Artesunate shows potent anti-tumor activity in B-cell lymphoma
    J. Hematol. Oncol., 11, 23
    DOI 10.1186/s13045-018-0561-0
  20. Vodak D, Lorenz S, Nakken S, Aasheim LB, Holte H, Bai B, Myklebost O, Meza-Zepeda LA, Hovig E (2018)
    Sample-Index Misassignment Impacts Tumour Exome Sequencing
    Sci Rep, 8, 5307
    DOI 10.1038/s41598-018-23563-4

Publications 2017

  1. Balasiddaiah A, Davanian H, Aleman S, Pasetto A, Frelin L, Sallberg M, Lohmann V, Koh S, Bertoletti A, Chen M (2017)
    Hepatitis C Virus-Specific T Cell Receptor mRNA-Engineered Human T Cells: Impact of Antigen Specificity on Functional Properties
    J. Virol., 91 (9), e00010
    DOI 10.1128/JVI.00010-17
  2. Bollum LK, Huse K, Oksvold MP, Bai BY, Hilden VI, Forfang L, Yoon SO, Walchli S, Smeland EB, Myklebust JH (2017)
    BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-beta receptor type I ALK5
    PLoS One, 12 (5), e0177188
    DOI 10.1371/journal.pone.0177188
  3. Cardoso I, Osterlund EC, Stamnaes J, Iversen R, Andersen JT, Jorgensen TJD, Sollid LM (2017)
    Dissecting the interaction between transglutaminase 2 and fibronectin
    Amino Acids, 49 (3), 489-500
    DOI 10.1007/s00726-016-2296-y
  4. Clancy T, Dannenfelser R, Troyanskaya O, Malmberg KJ, Hovig E, Kristensen V (2017)
    Bioinformatics Approaches to Profile the Tumor Microenvironment for Immunotherapeutic Discovery
    Curr. Pharm. Design, 23 (32), 4716-4725
    DOI 10.2174/1381612823666170710154936
  5. Henriksen EKK, Jorgensen KK, Kaveh F, Holm K, Hamm D, Olweus J, Melum E, Chung BK, Eide TJ, Lundin KEA, Boberg KM, Karlsen TH, Hirschfield GM, Liaskou E (2017)
    Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease
    J. Hepatol., 66 (1), 116-122
    DOI 10.1016/j.jhep.2016.09.002
  6. Hov JR, Boberg KM, Taraldsrud E, Vesterhus M, Boyadzhieva M, Solberg IC, Schrumpf E, Vatn MH, Lie BA, Molberg O, Karlsen TH (2017)
    Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis
    Liver Int., 37 (3), 458-465
    DOI 10.1111/liv.13238
  7. Inderberg EM, Walchli S, Myhre MR, Trachsel S, Almasbak H, Kvalheim G, Gaudernack G (2017)
    T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth
    OncoImmunology, 6 (4), e1302631
    DOI 10.1080/2162402X.2017.1302631
  8. Jha SK, Rauniyar K, Karpanen T, Leppanen VM, Brouillard P, Vikkula M, Alitalo K, Jeltsch M (2017)
    Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
    Sci Rep, 7, 4916
    DOI 10.1038/s41598-017-04982-1
  9. Karpanen T, Olweus J (2017)
    The Potential of Donor T-Cell Repertoires in Neoantigen-Targeted Cancer Immunotherapy
    Front. Immunol., 8, 1718
    DOI 10.3389/fimmu.2017.01718
  10. Koksal H, Walchli S (2017)
    Fishing therapeutic T-cell receptors in healthy donor blood, is safety predictable?
    Transl. Cancer Res., 6 3, S622-S624
    DOI 10.21037/tcr.2017.05.25
  11. Lilleby W, Gaudernack G, Brunsvig PF, Vlatkovic L, Schulz M, Mills K, Hole KH, Inderberg EM (2017)
    Phase I/IIa clinical trial of a novel hTERT peptide vaccine in men with metastatic hormone-naive prostate cancer
    Cancer Immunol. Immunother., 66 (7), 891-901
    DOI 10.1007/s00262-017-1994-y
  12. Liu LL, Beziat V, Oei VYS, Pfefferle A, Schaffer M, Lehmann S, Hellstrom-Lindberg E, Soderhall S, Heyman M, Grander D, Malmberg KJ (2017)
    Ex Vivo Expanded Adaptive NK Cells Effectively Kill Primary Acute Lymphoblastic Leukemia Cells
    Cancer Immunol. Res., 5 (8), 654-665
    DOI 10.1158/2326-6066.CIR-16-0296
  13. Malmberg KJ, Carlsten M, Bjorklund A, Sohlberg E, Bryceson YT, Ljunggren HG (2017)
    Natural killer cell-mediated immunosurveillance of human cancer
    Semin. Immunol., 31, 20-29
    DOI 10.1016/j.smim.2017.08.002
  14. Malmberg KJ, Sohlberg E, Goodridge JP, Ljunggren HG (2017)
    Immune selection during tumor checkpoint inhibition therapy paves way for NK-cell "missing self" recognition
    Immunogenetics, 69 (8-9), 547-556
    DOI 10.1007/s00251-017-1011-9
  15. Myklebust JH, Brody J, Kohrt HE, Kolstad A, Czerwinski DK, Walchli S, Green MR, Troen G, Liestol K, Beiske K, Houot R, Delabie J, Alizadeh AA, Irish JM, Levy R (2017)
    Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling
    Blood, 129 (6), 759-770
    DOI 10.1182/blood-2016-05-718494
  16. Olweus J (2017)
    Manufacture of CAR-T cells in the body
    Nat. Biotechnol., 35 (6), 520-521
    DOI 10.1038/nbt.3898
  17. Reiseter S, Gunnarsson R, Corander J, Haydon J, Lund MB, Aalokken TM, Taraldsrud E, Hetlevik SO, Molberg O (2017)
    Disease evolution in mixed connective tissue disease: results from a long-term nationwide prospective cohort study
    Arthritis Res. Ther., 19, 284
    DOI 10.1186/s13075-017-1494-7
  18. Scott DW, Abrisqueta P, Wright GW, Slack GW, Mottok A, Villa D, Jares P, Rauert-Wunderlich H, Royo C, Clot G, Pinyol M, Boyle M, Chan FC, Braziel RM, Chan WC, Weisenburger DD, Cook JR, Greiner TC, Fu K, Ott G, Delabie J, Smeland EB, Holte H, Jaffe ES, Steidl C et al. (2017)
    New Molecular Assay for the Proliferation Signature in Mantle Cell Lymphoma Applicable to Formalin-Fixed Paraffin-Embedded Biopsies
    J. Clin. Oncol., 35 (15), 1668-+
    DOI 10.1200/JCO.2016.70.7901
  19. Sike A, Wengenroth J, Upite J, Bruning T, Eiriz I, Santha P, Biverstal H, Jansone B, Haugen HJ, Krohn M, Pahnke J (2017)
    Improved method for cannula fixation for long-term intracerebral brain infusion
    J. Neurosci. Methods, 290, 145-150
    DOI 10.1016/j.jneumeth.2017.07.026
  20. Stuchly J, Kanderova V, Vlkova M, Hermanova I, Slamova L, Pelak O, Taraldsrud E, Jilek D, Kralickova P, Fevang B, Trkova M, Hrusak O, Fronkova E, Sediva A, Litzman J, Kalina T (2017)
    Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia
    Sci Rep, 7, 39710
    DOI 10.1038/srep39710
  21. Taraldsrud E, Aukrust P, Jorgensen S, Lingjaerde OC, Olweus J, Myklebust JH, Fevang B (2017)
    Patterns of constitutively phosphorylated kinases in B cells are associated with disease severity in common variable immunodeficiency
    Clin. Immunol., 175, 69-74
    DOI 10.1016/j.clim.2016.11.014
  22. Taraldsrud E, Fevang B, Jorgensen SF, Moltu K, Hilden V, Tasken K, Aukrust P, Myklebust JH, Olweus J (2017)
    Defective IL-4 signaling in T cells defines severe common variable immunodeficiency
    J. Autoimmun., 81, 110-119
    DOI 10.1016/j.jaut.2017.04.004
  23. Wagner JA, Rosario M, Romee R, Berrien-Elliott MM, Schneider SE, Leong JW, Sullivan RP, Jewell BA, Becker-Hapak M, Schappe T, Abdel-Latif S, Ireland AR, Jaishankar D, King JA, Vij R, Clement D, Goodridge J, Malmberg KJ, Wong HC, Fehniger TA (2017)
    CD56(bright) NK cells exhibit potent antitumor responses following IL-15 priming
    J. Clin. Invest., 127 (11), 4042-4058
    DOI 10.1172/JCI90387
  24. Waiseng E, Koksal H, Sektioglu IM, Fane A, Skorstad G, Kvalheim G, Gaudernack G, Inderberg EM, Walchli S (2017)
    A TCR-based Chimeric Antigen Receptor
    Sci Rep, 7, 10713
    DOI 10.1038/s41598-017-11126-y
  25. Wogsland CE, Greenplate AR, Kolstad A, Myklebust JH, Irish JM, Huse K (2017)
    Mass Cytometry of Follicular Lymphoma Tumors Reveals Intrinsic Heterogeneity in Proteins Including HLA-DR and a Deficit in Nonmalignant Plasmablast and Germinal Center B-Cell Populations
    Cytom. Part B-Clin. Cytom., 92 (1), 79-87
    DOI 10.1002/cyto.b.21498

Publications 2016

  1. Belnoue E, Di Berardino-Besson W, Gaertner H, Carboni S, Dunand-Sauthier I, Cerini F, Suso-Inderberg EM, Walchli S, Konig S, Salazar AM, Hartley O, Dietrich PY, Walker PR, Derouazi M (2016)
    Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants
    Mol. Ther., 24 (9), 1675-1685
    DOI 10.1038/mt.2016.134
  2. Bjorklund AT, Clancy T, Goodridge JP, Beziat V, Schaffer M, Hovig E, Ljunggren HG, Ljungman PT, Malmberg KJ (2016)
    Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
    J. Immunol., 196 (3), 1400-1411
    DOI 10.4049/jimmunol.1501434
  3. Blaker YN, Spetalen S, Brodtkorb M, Lingjaerde OC, Beiske K, Ostenstad B, Sander B, Wahlin BE, Melen CM, Myklebust JH, Holte H, Delabie J, Smeland EB (2016)
    The tumour microenvironment influences survival and time to transformation in follicular lymphoma in the rituximab era
    Br. J. Haematol., 175 (1), 102-114
    DOI 10.1111/bjh.14201
  4. Cairns L, Aspeslagh S, Anichini A, Kyte JA, Blank C, Ascierto P, Rekers N, Straten PT, Awada A (2016)
    Cancer immunotherapy: from the lab to clinical applications-Potential impact on cancer centres' organisation
    eCancerMedicalScience, 10, 691
    DOI 10.3332/ecancer.2016.691
  5. Clancy T, Hovig E (2016)
    Profiling networks of distinct immune-cells in tumors
    BMC Bioinformatics, 17, 263
    DOI 10.1186/s12859-016-1141-3
  6. Eide HA, Halvorsen AR, Sandhu V, Fane A, Berg J, Haakensen VD, Kure EH, Brustugun OT, Kiserud CE, Kyte JA, Helland A (2016)
    Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease
    Clin. Transl. Immunol., 5, e109
    DOI 10.1038/cti.2016.65
  7. Holm KL, Indrevaer RL, Myklebust JH, Kolstad A, Moskaug JO, Naderi EH, Blomhoff HK (2016)
    Myeloid cell leukaemia 1 has a vital role in retinoic acid-mediated protection of Toll-like receptor 9-stimulated B cells from spontaneous and DNA damage-induced apoptosis
    Immunology, 149 (1), 62-73
    DOI 10.1111/imm.12629
  8. Horowitz A, Djaoud Z, Nemat-Gorgani N, Blokhuis J, Hilton HG, Beziat V, Malmberg KJ, Norman PJ, Guethlein LA, Parham P (2016)
    Class I HLA haplotypes form two schools that educate NK cells in different ways
    Sci. Immunol., 1 (3), eaag1672
    DOI 10.1126/sciimmunol.aag1672
  9. Haabeth OAW, Lorvik KB, Yagita H, Bogen B, Corthay A (2016)
    Interleukin-1 is required for cancer eradication mediated by tumor-specific Th1 cells
    OncoImmunology, 5 (1), e1039763
    DOI 10.1080/2162402X.2015.1039763
  10. Kyte JA, Gaudernack G, Faane A, Lislerud K, Inderberg EM, Brunsvig P, Aamdal S, Kvalheim G, Walchli S, Pule M (2016)
    T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy
    OncoImmunology, 5 (12), e1249090
    DOI 10.1080/2162402X.2016.1249090
  11. Kyte JA, Aamdal S, Dueland S, Saeboe-Larsen S, Inderberg EM, Madsbu UE, Skovlund E, Gaudernack G, Kvalheim G (2016)
    Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells
    OncoImmunology, 5 (11), e1232237
    DOI 10.1080/2162402X.2016.1232237
  12. Landtwing V, Raykova A, Pezzino G, Beziat V, Marcenaro E, Graf C, Moretta A, Capaul R, Zbinden A, Ferlazzo G, Malmberg KJ, Chijioke O, Munz C (2016)
    Cognate HLA absence in trans diminishes human NK cell education
    J. Clin. Invest., 126 (10), 3772-3782
    DOI 10.1172/JCI86923
  13. Liaskou E, Henriksen EKK, Holm K, Kaveh F, Hamm D, Fear J, Viken MK, Hov JR, Melum E, Robins H, Olweus J, Karlsen TH, Hirschfield GM (2016)
    High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires
    Hepatology, 63 (5), 1608-1619
    DOI 10.1002/hep.28116
  14. Liu LL, Landskron J, Ask EH, Enqvist M, Sohlberg E, Traherne JA, Hammer Q, Goodridge JP, Larsson S, Jayaraman J, Oei VYS, Schaffer M, Tasken K, Ljunggren HG, Romagnani C, Trowsdale J, Malmberg KJ, Beziat V (2016)
    Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans
    Cell Reports, 15 (5), 1088-1099
    DOI 10.1016/j.celrep.2016.04.005
  15. Lorvik KB, Hammarstrom C, Fauskanger M, Haabeth OAW, Zangani M, Haraldsen G, Bogen B, Corthay A (2016)
    Adoptive Transfer of Tumor-Specific Th2 Cells Eradicates Tumors by Triggering an In Situ Inflammatory Immune Response
    Cancer Res., 76 (23), 6864-6876
    DOI 10.1158/0008-5472.CAN-16-1219
  16. Mensali N, Ying F, Sheng VOY, Yang WW, Walseng E, Kumari S, Fallang LE, Kolstad A, Uckert W, Malmberg KJ, Walchli S, Olweus J (2016)
    Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA
    OncoImmunology, 5 (5), e1138199
    DOI 10.1080/2162402X.2016.1138199
  17. Mobergslien A, Peng Q, Vasovic V, Sioud M (2016)
    Cancer cell-binding peptide fused Fc domain activates immune effector cells and blocks tumor growth
    Oncotarget, 7 (46), 75940-75953
    DOI 10.18632/oncotarget.12445
  18. Oksvold MP (2016)
    Incidence of Data Duplications in a Randomly Selected Pool of Life Science Publications
    Sci. Eng. Ethics, 22 (2), 487-496
    DOI 10.1007/s11948-015-9668-7
  19. Sioud M, Nyakas M, Saeboe-Larssen S, Mobergslien A, Aamdal S, Kvalheim G (2016)
    Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine
    Case Rep. Med., 2016, 9639585
    DOI 10.1155/2016/9639585
  20. Stronen E, Toebes M, Kelderman S, van Buuren MM, Yang WW, van Rooij N, Donia M, Boschen ML, Lund-Johansen F, Olweus J, Schumacher TN (2016)
    Targeting of cancer neoantigens with donor-derived T cell receptor repertoires
    Science, 352 (6291), 1337-1341
    DOI 10.1126/science.aaf2288
  21. Theodossiou TA, Walchli S, Olsen CE, Skarpen E, Berg K (2016)
    Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
    ACS Chem. Biol., 11 (1), 251-262
    DOI 10.1021/acschembio.5b00734
  22. Vatsveen TK, Borset M, Dikic A, Tian EM, Micci F, Lid AHB, Meza-Zepeda LA, Coward E, Waage A, Sundan A, Kuehl WM, Holien T (2016)
    VOLIN and KJONTwo novel hyperdiploid myeloma cell lines
    Gene Chromosomes Cancer, 55 (11), 890-901
    DOI 10.1002/gcc.22388
  23. Walter JE, Farmer JR, Foldvari Z, Torgerson TR, Cooper MA (2016)
    Mechanism-Based Strategies for the Management of Autoimmunity and Immune Dysregulation in Primary Immunodeficiencies
    J. Allergy Clin. Immunol.-Pract., 4 (6), 1089-1100
    DOI 10.1016/j.jaip.2016.08.004
  24. Winnay JN, Solheim MH, Dirice E, Sakaguchi M, Noh HL, Kang HJ, Takahashi H, Chudasama KK, Kim JK, Molven A, Kahn CR, Njolstad PR (2016)
    PI3-kinase mutation linked to insulin and growth factor resistance in vivo
    J. Clin. Invest., 126 (4), 1401-1412
    DOI 10.1172/JCI84005
  25. Zhao F, Sucker A, Horn S, Heeke C, Bielefeld N, Schrors B, Bicker A, Lindemann M, Roesch A, Gaudernack G, Stiller M, Becker JC, Lennerz V, Wolfel T, Schadendorf D, Griewank K, Paschen A (2016)
    Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic Latency
    Cancer Res., 76 (15), 4347-4358
    DOI 10.1158/0008-5472.CAN-16-0008
  26. Zins K, Schafer R, Paulus P, Dobler S, Fakhari N, Sioud M, Aharinejad S, Abraham D (2016)
    Frizzled2 signaling regulates growth of high-risk neuroblastomas by interfering with beta-catenin-dependent and beta-catenin-independent signaling pathways
    Oncotarget, 7 (29), 46187-46202
    DOI 10.18632/oncotarget.10070

Publications 2015

  1. Almasbak H, Walseng E, Kristian A, Myhre MR, Suso EM, Munthe LA, Andersen JT, Wang MY, Kvalheim G, Gaudernack G, Kyte JA (2015)
    Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model
    Gene Ther., 22 (5), 391-403
    DOI 10.1038/gt.2015.4
  2. Beziat V, Sleiman M, Goodridge JP, Kaarbo M, Liu LL, Rollag H, Ljunggren HG, Zimmer J, Malmberg KJ (2015)
    Polyclonal expansion of NKG2C(+) NK cells in TAP-deficient patients
    Front. Immunol., 6, 507
    DOI 10.3389/fimmu.2015.00507
  3. Blaker YN, Brodtkorb M, Maddison J, Hveem TS, Nesheim JA, Mohn HM, Kolstad A, Geisler CH, Liestol K, Smeland EB, Holte H, Delabie J, Danielsen H (2015)
    Computerized image analysis of the Ki-67 proliferation index in mantle cell lymphoma
    Histopathology, 67 (1), 62-69
    DOI 10.1111/his.12624
  4. Blix ES, Kilda AB, Bertelsen E, Waage A, Myklebust JH, Kolstad A, Husebekk A (2015)
    Content of Endothelial Progenitor Cells in Autologous Stem Cell Grafts Predict Survival after Transplantation for Multiple Myeloma
    Biol. Blood Marrow Transplant., 21 (5), 840-847
    DOI 10.1016/j.bbmt.2014.12.027
  5. Calejo AI, Tasken K (2015)
    Targeting protein-protein interactions in complexes organized by A kinase anchoring proteins
    Front. Pharmacol., 6, 192
    DOI 10.3389/fphar.2015.00192
  6. Enqvist M, Ask EH, Forslund E, Carlsten M, Abrahamsen G, Beziat V, Andersson S, Schaffer M, Spurkland A, Bryceson Y, Onfelt B, Malmberg KJ (2015)
    Coordinated Expression of DNAM-1 and LFA-1 in Educated NK Cells
    J. Immunol., 194 (9), 4518-4527
    DOI 10.4049/jimmunol.1401972
  7. Fiskvik I, Beiske K, Delabie J, Yri O, Spetalen S, Karjalainen-Lindsberg ML, Leppa S, Liestol K, Smeland EB, Holte H (2015)
    Combining MYC, BCL2 and TP53 gene and protein expression alterations improves risk stratification in diffuse large B-cell lymphoma
    Leuk. Lymphoma, 56 (6), 1742-1749
    DOI 10.3109/10428194.2014.970550
  8. Forslund E, Sohlberg E, Enqvist M, Olofsson PE, Malmberg KJ, Onfelt B (2015)
    Microchip-Based Single-Cell Imaging Reveals That CD56(dim) CD57(-)KIR(-)NKG2A(+) NK Cells Have More Dynamic Migration Associated with Increased Target Cell Conjugation and Probability of Killing Compared to CD56(dim)CD57(-)KIR(-)NKG2A(-) NK Cells
    J. Immunol., 195 (7), 3374-3381
    DOI 10.4049/jimmunol.1500171
  9. Goodridge JP, Onfelt B, Malmberg KJ (2015)
    Newtonian cell interactions shape natural killer cell education
    Immunol. Rev., 267 (1), 197-213
    DOI 10.1111/imr.12325
  10. Hansen GL, Gaudernack G, Brunsvig PF, Cvancarova M, Kyte JA (2015)
    Immunological factors influencing clinical outcome in lung cancer patients after telomerase peptide vaccination
    Cancer Immunol. Immunother., 64 (12), 1609-1621
    DOI 10.1007/s00262-015-1766-5
  11. Karpanen T, Olweus J (2015)
    T-cell receptor gene therapy - ready to go-viral?
    Mol. Oncol., 9 (10), 2019-2042
    DOI 10.1016/j.molonc.2015.10.006
  12. Kolstad A, Kumari S, Walczak M, Madsbu U, Hagtvedt T, Bogsrud TV, Kvalheim G, Holte H, Aurlien E, Delabie J, Tierens A, Olweus J (2015)
    Sequential intranodal immunotherapy induces antitumor immunity and correlated regression of disseminated follicular lymphoma
    Blood, 125 (1), 82-89
    DOI 10.1182/blood-2014-07-592162
  13. Kolstad A, Olweus J (2015)
    "In situ" vaccination for systemic effects in follicular lymphoma
    OncoImmunology, 4 (7), e1014773
    DOI 10.1080/2162402X.2015.1014773
  14. Liu LL, Pfefferle A, Sheng VOY, Bjorklund AT, Beziat V, Goodridge JP, Malmberg KJ (2015)
    Harnessing adaptive natural killer cells in cancer immunotherapy
    Mol. Oncol., 9 (10), 1904-1917
    DOI 10.1016/j.molonc.2015.10.001
  15. Lunemann S, Malone DFG, Grabowski J, Port K, Beziat V, Bremer B, Malmberg KJ, Manns MP, Sandberg JK, Cornberg M, Ljunggren HG, Wedemeyer H, Bjorkstrom NK (2015)
    Effects of HDV infection and pegylated interferon a treatment on the natural killer cell compartment in chronically infected individuals
    Gut, 64 (3), 469-482
    DOI 10.1136/gutjnl-2014-306767
  16. Malecka A, Tierens A, Ostlie I, Schmitz R, Troen G, Spetalen S, Staudt LM, Smeland E, Holte H, Delabie J (2015)
    Primary diffuse large B-cell lymphoma associated with clonally-related monoclonal B lymphocytosis indicates a common precursor cell
    Haematologica, 100 (10), E415-E418
    DOI 10.3324/haematol.2015.126656
  17. Mobergslien A, Vasovic V, Mathiesen G, Fredriksen L, Westby P, Eijsink VGH, Peng Q, Sioud M (2015)
    Recombinant Lactobacillus plantarum induces immune responses to cancer testis antigen NY-ESO-1 and maturation of dendritic cells
    Human Vaccines Immunother., 11 (11), 2664-2673
    DOI 10.1080/21645515.2015.1056952
  18. Oksvold MP, Duyvestyn JM, Dagger SA, Taylor SJ, Forfang L, Myklebust JH, Smeland EB, Langdon WY (2015)
    The targeting of human and mouse B lymphocytes by dasatinib
    Exp. Hematol., 43 (5), 352-363
    DOI 10.1016/j.exphem.2015.01.008
  19. Olweus J (2015)
    Cancer immunotherapy - Converting immune failure to clinical response
    Mol. Oncol., 9 (10), 1891-1893
    DOI 10.1016/j.molonc.2015.10.017
  20. Polikowsky HG, Wogsland CE, Diggins KE, Huse K, Irish JM (2015)
    Cutting Edge: Redox Signaling Hypersensitivity Distinguishes Human Germinal Center B Cells
    J. Immunol., 195 (4), 1364-1367
    DOI 10.4049/jimmunol.1500904
  21. Rein ID, Stokke C, Jalal M, Myklebust JH, Patzke S, Stokke T (2015)
    New distinct compartments in the G(2) phase of the cell cycle defined by the levels of gamma H2AX
    Cell Cycle, 14 (20), 3261-3269
    DOI 10.1080/15384101.2015.1087617
  22. Riihijarvi S, Fiskvik I, Taskinen M, Vajavaara H, Tikkala M, Yri O, Karjalainen-Lindsberg ML, Delabie J, Smeland E, Holte H, Leppa S (2015)
    Prognostic influence of macrophages in patients with diffuse large B-cell lymphoma: a correlative study from a Nordic phase II trial
    Haematologica, 100 (2), 238-245
    DOI 10.3324/haematol.2014.113472
  23. Schlums H, Cichocki F, Tesi B, Theorell J, Beziat V, Holmes TD, Han HY, Chiang SCC, Foley B, Mattsson K, Larsson S, Schaffer M, Malmberg KJ, Ljunggren HG, Miller JS, Bryceson YT (2015)
    Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function
    Immunity, 42 (3), 443-456
    DOI 10.1016/j.immuni.2015.02.008
  24. Sioud M, Westby P, Olsen JKE, Mobergslien A (2015)
    Generation of new peptide-Fc fusion proteins that mediate antibody-dependent cellular cytotoxicity against different types of cancer cells
    Mol.Ther.-Methods Clin. Dev., 2, 15043
    DOI 10.1038/mtm.2015.43
  25. Sobecks RM, Wang T, Askar M, Gallagher MM, Haagenson M, Spellman S, Fernandez-Vina M, Malmberg KJ, Muller C, Battiwalla M, Gajewski J, Verneris MR, Ringden O, Marino S, Davies S, Dehn J, Bornhauser M, Inamoto Y, Woolfrey A, Shaw P, Pollack M, Weisdorf D, Milller J, Hurley C, Lee SJ et al. (2015)
    Impact of KIR and HLA Genotypes on Outcomes after Reduced-Intensity Conditioning Hematopoietic Cell Transplantation
    Biol. Blood Marrow Transplant., 21 (9), 1589-1596
    DOI 10.1016/j.bbmt.2015.05.002
  26. Sohlberg E, Pfefferle A, Andersson S, Baumann BC, Hellstrom-Lindberg E, Malmberg KJ (2015)
    Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome
    Oncotarget, 6 (33), 34178-34190
    DOI 10.18632/oncotarget.6213
  27. Tadesse FG, Mensali N, Fallang LE, Walseng E, Yang WW, Olweus J, Walchli S (2015)
    Unpredicted phenotypes of two mutants of the TcR DMF5
    J. Immunol. Methods, 425, 37-44
    DOI 10.1016/j.jim.2015.06.006
  28. von Bahr L, Blennow O, Alm J, Bjorklund A, Malmberg KJ, Mougiakakos D, Le Blanc A, Oefner PJ, Labopin M, Ljungman P, Le Blanc K (2015)
    Increased incidence of chronic GvHD and CMV disease in patients with vitamin D deficiency before allogeneic stem cell transplantation
    Bone Marrow Transplant., 50 (9), 1217-1223
    DOI 10.1038/bmt.2015.123
  29. Walseng E, Walchli S, Fallang LE, Yang WW, Vefferstad A, Areffard A, Olweus J (2015)
    Soluble T-Cell Receptors Produced in Human Cells for Targeted Delivery
    PLoS One, 10 (4), e0119559
    DOI 10.1371/journal.pone.0119559

Publications 2014

  1. Azzi T, Lunemann A, Murer A, Ueda S, Beziat V, Malmberg KJ, Staubli G, Gysin C, Berger C, Munz C, Chijioke O, Nadal D (2014)
    Role for early-differentiated natural killer cells in infectious mononucleosis
    Blood, 124 (16), 2533-2543
    DOI 10.1182/blood-2014-01-553024
  2. Bengner M, Beziat V, Ernerudh J, Nilsson BO, Lofgren S, Wikby A, Malmberg KJ, Strindhall J (2014)
    Independent skewing of the T cell and NK cell compartments associated with cytomegalovirus infection suggests division of labor between innate and adaptive immunity
    Age, 36 (2), 571-582
    DOI 10.1007/s11357-013-9587-y
  3. Bethge N, Honne H, Andresen K, Hilden V, Troen G, Liestol K, Holte H, Delabie J, Lind GE, Smeland EB (2014)
    A Gene Panel, Including LRP12, Is Frequently Hypermethylated in Major Types of B-Cell Lymphoma
    PLoS One, 9 (9), e104249
    DOI 10.1371/journal.pone.0104249
  4. Bethge N, Lothe RA, Honne H, Andresen K, Troen G, Eknaes M, Liestol K, Holte H, Delabie J, Smeland EB, Lind GE (2014)
    Colorectal cancer DNA methylation marker panel validated with high performance in Non-Hodgkin lymphoma
    Epigenetics, 9 (3), 428-436
    DOI 10.4161/epi.27554
  5. Beziat V, Traherne J, Malmberg JA, Ivarsson MA, Bjorkstrom NK, Retiere C, Ljunggren HG, Michaelsson J, Trowsdale J, Malmberg KJ (2014)
    Tracing dynamic expansion of human NK-cell subsets by high-resolution analysis of KIR repertoires and cellular differentiation
    Eur. J. Immunol., 44 (7), 2192-2196
    DOI 10.1002/eji.201444464
  6. Blaker YN, Eide MB, Liestol K, Lauritzsen GF, Kolstad A, Fossa A, Smeland EB, Holte H (2014)
    High dose chemotherapy with autologous stem cell transplant for patients with transformed B-cell non-Hodgkin lymphoma in the rituximab era
    Leuk. Lymphoma, 55 (10), 2319-2327
    DOI 10.3109/10428194.2013.871632
  7. Brodtkorb M, Lingjaerde OC, Huse K, Troen G, Hystad M, Hilden VI, Myklebust JH, Leich E, Rosenwald A, Delabie J, Holte H, Smeland EB (2014)
    Whole-genome integrative analysis reveals expression signatures predicting transformation in follicular lymphoma
    Blood, 123 (7), 1051-1054
    DOI 10.1182/blood-2013-07-512392
  8. del Campo AB, Kyte JA, Carretero J, Zinchencko S, Mendez R, Gonzalez-Aseguinolaza G, Ruiz-Cabello F, Aamdal S, Gaudernack G, Garrido F, Aptsiauri N (2014)
    Immune escape of cancer cells with beta2-microglobulin loss over the course of metastatic melanoma
    Int. J. Cancer, 134 (1), 102-113
    DOI 10.1002/ijc.28338
  9. Haugaa H, Taraldsrud E, Nyrerod HC, Tonnessen TI, Foss A, Solheim BG (2014)
    Low Incidence of Hyperfibrinolysis and Thromboembolism in 195 Primary Liver Transplantations Transfused with Solvent/Detergent-Treated Plasma
    Clin. Med. Res., 12 (1-2), 27-32
    DOI 10.3121/cmr.2013.1168
  10. Kumari S, Walchli S, Fallang LE, Yang WW, Lund-Johansen F, Schumacher TN, Olweus J (2014)
    Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes
    Proc. Natl. Acad. Sci. U. S. A., 111 (1), 403-408
    DOI 10.1073/pnas.1306549111
  11. Lossius A, Johansen JN, Vartdal F, Robins H, Saltyte BJ, Holmoy T, Olweus J (2014)
    High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8(+) T cells
    Eur. J. Immunol., 44 (11), 3439-3452
    DOI 10.1002/eji.201444662
  12. Mobergslien A, Sioud M (2014)
    Exosome-Derived miRNAs and Cellular miRNAs Activate Innate Immunity
    J. Innate Immun., 6 (1), 105-110
    DOI 10.1159/000351460
  13. Munneke JM, Bjorklund AT, Mjosberg JM, Garming-Legert K, Bernink JH, Blom B, Huisman C, van Oers MHJ, Spits H, Malmberg KJ, Hazenberg MD (2014)
    Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease
    Blood, 124 (5), 812-821
    DOI 10.1182/blood-2013-11-536888
  14. Muppidi JR, Schmitz R, Green JA, Xiao WM, Larsens AB, Braun SE, An JP, Xu Y, Rosenwald A, Ott G, Gascoyne RD, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Vaidehi N, Staudt LM, Cyster JG (2014)
    Loss of signalling via G alpha 13 in germinal centre B-cell-derived lymphoma
    Nature, 516 (7530), 254-+
    DOI 10.1038/nature13765
  15. Oksvold MP, Kullmann A, Forfang L, Kierulf B, Li M, Brech A, Vlassov AV, Smeland EB, Neurauter A, Pedersen KW (2014)
    Expression of B-Cell Surface Antigens in Subpopulations of Exosomes Released From B-Cell Lymphoma Cells
    Clin. Ther., 36 (6), 847-862
    DOI 10.1016/j.clinthera.2014.05.010
  16. Scott DW, Wright GW, Williams PM, Lih CJ, Walsh W, Jaffe ES, Rosenwald A, Campo E, Chan WC, Connors JM, Smeland EB, Mottok A, Braziel RM, Ott G, Delabie J, Tubbs RR, Cook JR, Weisenburger DD, Greiner TC, Glinsmann-Gibson BJ, Fu K, Staudt LM, Gascoyne RD, Rimsza LM (2014)
    Determining cell-of-origin subtypes of diffuse large B-cell lymphoma using gene expression in formalin-fixed paraffin-embedded tissue
    Blood, 123 (8), 1214-1217
    DOI 10.1182/blood-2013-11-536433
  17. Sioud M (2014)
    Engineering better immunotherapies via RNA interference
    Human Vaccines Immunother., 10 (11), 3165-3174
    DOI 10.4161/hv.29754
  18. Taraldsrud E, Fevang B, Aukrust P, Beiske KH, Floisand Y, Froland S, Rollag H, Olweus J (2014)
    Common variable immunodeficiency revisited: normal generation of naturally occurring dendritic cells that respond to Toll-like receptors 7 and 9
    Clin. Exp. Immunol., 175 (3), 439-448
    DOI 10.1111/cei.12239
  19. Wahlin BE, Sundstrom C, Sander B, Christensson B, Jeppsson-Ahlberg A, Hjalmarsson E, Holte H, Ostenstad B, Brown PD, Smeland EB, Kimby E (2014)
    Higher World Health Organization grades of follicular lymphoma correlate with better outcome in two Nordic Lymphoma Group trials of rituximab without chemotherapy
    Leuk. Lymphoma, 55 (2), 288-295
    DOI 10.3109/10428194.2013.802778
  20. Walchli S, Kumari S, Fallang LE, Sand KMK, Yang WW, Landsverk OJB, Bakke O, Olweus J, Gregers TF (2014)
    Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation
    Eur. J. Immunol., 44 (3), 774-784
    DOI 10.1002/eji.201343671
  21. Yang YB, Schmitz R, Mitala J, Whiting A, Xiao WM, Ceribelli M, Wright GW, Zhao H, Yang YD, Xu WH, Rosenwald A, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Wiestner A et al. (2014)
    Essential Role of the Linear Ubiquitin Chain Assembly Complex in Lymphoma Revealed by Rare Germline Polymorphisms
    Cancer Discov., 4 (4), 480-493
    DOI 10.1158/2159-8290.CD-13-0915

Publications 2013

  1. Arita A, McFarland DC, Myklebust JH, Parekh S, Petersen B, Gabrilove J, Brody JD (2013)
    Signaling pathways in lymphoma: pathogenesis and therapeutic targets
    Future Oncol., 9 (10), 1549-1571
    DOI 10.2217/fon.13.113
  2. Bethge N, Honne H, Hilden V, Troen G, Eknaes M, Liestol K, Holte H, Delabie J, Smeland EB, Lind GE (2013)
    Identification of Highly Methylated Genes across Various Types of B-Cell Non-Hodgkin Lymphoma
    PLoS One, 8 (11), e79602
    DOI 10.1371/journal.pone.0079602
  3. Beziat V, Liu LL, Malmberg JA, Ivarsson MA, Sohlberg E, Bjorklund AT, Retiere C, Sverremark-Ekstrom E, Traherne J, Ljungman P, Schaffer M, Price DA, Trowsdale J, Michaelsson J, Ljunggren HG, Malmberg KJ (2013)
    NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs
    Blood, 121 (14), 2678-2688
    DOI 10.1182/blood-2012-10-459545
  4. Beziat V, Traherne JA, Liu LL, Jayaraman J, Enqvist M, Larsson S, Trowsdale J, Malmberg KJ (2013)
    Influence of KIR gene copy number on natural killer cell education
    Blood, 121 (23), 4703-4707
    DOI 10.1182/blood-2012-10-461442
  5. Bodor C, Grossmann V, Popov N, Okosun J, O'Riain C, Tan K, Marzec J, Araf S, Wang J, Lee AM, Clear A, Montoto S, Matthews J, Iqbal S, Rajnai H, Rosenwald A, Ott G, Campo E, Rimsza LM, Smeland EB, Chan WC, Braziel RM, Staudt LM, Wright G, Lister TA et al. (2013)
    EZH2 mutations are frequent and represent an early event in follicular lymphoma
    Blood, 122 (18), 3165-3168
    DOI 10.1182/blood-2013-04-496893
  6. Dollner R, Taraldsrud E, Iversen K, Osnes T, Kristensen B, Kramer MF (2013)
    Non-allergic, mastocytosis-associated rhinitis
    Clin. Exp. Allergy, 43 (4), 406-412
    DOI 10.1111/cea.12053
  7. Fiskvik I, Aamot HV, Delabie J, Smeland EB, Stokke T, Heim S, Holte H (2013)
    Karyotyping of diffuse large B-cell lymphomas: loss of 17p is associated with poor patient outcome
    Eur. J. Haematol., 91 (4), 332-338
    DOI 10.1111/ejh.12171
  8. Gregers TF, Skanland SS, Walchli S, Bakke O, Sandvig K (2013)
    BiP Negatively Affects Ricin Transport
    Toxins, 5 (5), 969-982
    DOI 10.3390/toxins5050969
  9. Myklebust JH, Irish JM, Brody J, Czerwinski DK, Houot R, Kohrt HE, Timmerman J, Said J, Green MR, Delabie J, Kolstad A, Alizadeh AA, Levy R (2013)
    High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells
    Blood, 121 (8), 1367-1376
    DOI 10.1182/blood-2012-04-421826
  10. Shahzidi S, Brech A, Sioud M, Li XR, Suo ZH, Nesland JM, Peng Q (2013)
    Lamin A/C cleavage by caspase-6 activation is crucial for apoptotic induction by photodynamic therapy with hexaminolevulinate in human B-cell lymphoma cells
    Cancer Lett., 339 (1), 25-32
    DOI 10.1016/j.canlet.2013.07.026
  11. Sioud M, Saeboe-Larssen S, Hetland TE, Kaern J, Mobergslien A, Kvalheim G (2013)
    Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients
    Int. J. Oncol., 43 (1), 280-288
    DOI 10.3892/ijo.2013.1922
  12. Sioud M, Skorstad G, Mobergslien A, Sboe-Larssen S (2013)
    A novel peptide carrier for efficient targeting of antigens and nucleic acids to dendritic cells
    Faseb J., 27 (8), 3272-3283
    DOI 10.1096/fj.12-224758
  13. Sternberg-Simon M, Brodin P, Pickman Y, Onfelt B, Karre K, Malmberg KJ, Hoglund P, Mehr R (2013)
    Natural killer cell inhibitory receptor expression in humans and mice: a closer look
    Front. Immunol., 4, 65
    DOI 10.3389/fimmu.2013.00065
  14. Vanherberghen B, Olofsson PE, Forslund E, Sternberg-Simon M, Khorshidi MA, Pacouret S, Guldevall K, Enqvist M, Malmberg KJ, Mehr R, Onfelt B (2013)
    Classification of human natural killer cells based on migration behavior and cytotoxic response
    Blood, 121 (8), 1326-1334
    DOI 10.1182/blood-2012-06-439851
  15. Vik-Mo EO, Nyakas M, Mikkelsen BV, Moe MC, Due-Tonnesen P, Suso EMI, Saeboe-Larssen S, Sandberg C, Brinchmann JE, Helseth E, Rasmussen AM, Lote K, Aamdal S, Gaudernack G, Kvalheim G, Langmoen IA (2013)
    Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma
    Cancer Immunol. Immunother., 62 (9), 1499-1509
    DOI 10.1007/s00262-013-1453-3
  16. Wang P, Gao QL, Suo ZH, Munthe E, Solberg S, Ma LW, Wang MY, Westerdaal NAC, Kvalheim G, Gaudernack G (2013)
    Identification and Characterization of Cells with Cancer Stem Cell Properties in Human Primary Lung Cancer Cell Lines
    PLoS One, 8 (3), e57020
    DOI 10.1371/journal.pone.0057020
  17. Wang P, Suo ZH, Wang M, Hoifodt HK, Fodstad O, Gaudernack G, Kvalheim G (2013)
    In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines
    Exp. Hematol. Oncol., 2, 16
    DOI 10.1186/2162-3619-2-16
  18. Yri OE, Ekstrom PO, Hilden V, Gaudernack G, Liestol K, Smeland EB, Holte H (2013)
    Influence of polymorphisms in genes encoding immunoregulatory proteins and metabolizing enzymes on susceptibility and outcome in patients with diffuse large B-cell lymphoma treated with rituximab
    Leuk. Lymphoma, 54 (10), 2205-2214
    DOI 10.3109/10428194.2013.774392
  19. Zins K, Thomas A, Lucas T, Sioud M, Aharinejad S, Abraham D (2013)
    Inhibition of Stromal PlGF Suppresses the Growth of Prostate Cancer Xenografts
    Int. J. Mol. Sci., 14 (9), 17958-17971
    DOI 10.3390/ijms140917958

Publications 2012

  1. Abrahamsen IW, Kjellevoll S, Greve-Isdahl M, Mensali N, Walchli S, Kumari S, Loland BF, Egeland T, Kolstad A, Olweus J (2012)
    T cells raised against allogeneic HLA-A2/CD20 kill primary follicular lymphoma and acute lymphoblastic leukemia cells
    Int. J. Cancer, 130 (8), 1821-1832
    DOI 10.1002/ijc.26209
  2. Adamczak M, Hoel HJ, Gaudernack G, Barbasz J, Szczepanowicz K, Warszynski P (2012)
    Polyelectrolyte multilayer capsules with quantum dots for biomedical applications
    Colloid Surf. B-Biointerfaces, 90, 211-216
    DOI 10.1016/j.colsurfb.2011.10.028
  3. Bakkebo M, Huse K, Hilden VI, Forfang L, Myklebust JH, Smeland EB, Oksvold MP (2012)
    SARA is dispensable for functional TGF-beta signaling
    FEBS Lett., 586 (19), 3367-3372
    DOI 10.1016/j.febslet.2012.07.027
  4. Banik D, Khan ANH, Walseng E, Segal BH, Abrams SI (2012)
    Interferon Regulatory Factor-8 Is Important for Histone Deacetylase Inhibitor-Mediated Antitumor Activity
    PLoS One, 7 (9), e45422
    DOI 10.1371/journal.pone.0045422
  5. Bjorkstrom NK, Beziat V, Cichocki F, Liu LL, Levine J, Larsson S, Koup RA, Anderson SK, Ljunggren HG, Malmberg KJ (2012)
    CD8 T cells express randomly selected KIRs with distinct specificities compared with NK cells
    Blood, 120 (17), 3455-3465
    DOI 10.1182/blood-2012-03-416867
  6. Blix ES, Irish JM, Husebekk A, Delabie J, Forfang L, Tierens AM, Myklebust JH, Kolstad A (2012)
    Phospho-specific flow cytometry identifies aberrant signaling in indolent B-cell lymphoma
    BMC Cancer, 12, 478
    DOI 10.1186/1471-2407-12-478
  7. Blix ES, Irish JM, Husebekk A, Delabie J, Tierens AM, Myklebust JH, Kolstad A (2012)
    Altered BCR and CD40 signalling are associated with clinical outcome in small lymphocytic lymphoma/chronic lymphocytic leukaemia and marginal zone lymphoma patients
    Br. J. Haematol., 159 (5), 604-608
    DOI 10.1111/bjh.12073
  8. Holien T, Vatsveen TK, Hella H, Rampa C, Brede G, Groseth LAG, Rekvig M, Borset M, Standal T, Waage A, Sundan A (2012)
    Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC
    Leukemia, 26 (5), 1073-1080
    DOI 10.1038/leu.2011.263
  9. Huse K, Bakkebo M, Walchli S, Oksvold MP, Hilden VI, Forfang L, Bredahl ML, Liestol K, Alizadeh AA, Smeland EB, Myklebust JH (2012)
    Role of Smad Proteins in Resistance to BMP-Induced Growth Inhibition in B-Cell Lymphoma
    PLoS One, 7 (10), e46117
    DOI 10.1371/journal.pone.0046117
  10. Inderberg-Suso EM, Trachsel S, Lislerud K, Rasmussen AM, Gaudernack G (2012)
    Widespread CD4(+) T-cell reactivity to novel hTERT epitopes following vaccination of cancer patients with a single hTERT peptide GV1001
    OncoImmunology, 1 (5), 670-686
    DOI 10.4161/onci.20426
  11. Kumari S, Misra P, Tandon R, Samant M, Sundar S, Dube A (2012)
    Leishmania donovani: Immunostimulatory Cellular Responses of Membrane and Soluble Protein Fractions of Splenic Amastigotes in Cured Patient and Hamsters
    PLoS One, 7 (1), e30746
    DOI 10.1371/journal.pone.0030746
  12. Malmberg KJ (2012)
    Toward a prime-boost regime for NK cells?
    Blood, 120 (24), 4663-4664
    DOI 10.1182/blood-2012-09-457184
  13. Malmberg KJ, Beziat V, Ljunggren HG (2012)
    Spotlight on NKG2C and the human NK-cell response to CMV infection
    Eur. J. Immunol., 42 (12), 3141-3145
    DOI 10.1002/eji.201243050
  14. Mobergslien A, Sioud M (2012)
    Galectin-1 and-3 gene silencing in immature and mature dendritic cells enhances T cell activation and interferon-gamma production
    J. Leukoc. Biol., 91 (3), 461-467
    DOI 10.1189/jlb.0711361
  15. Nilsen G, Liestol K, Van Loo P, Vollan HKM, Eide MB, Rueda OM, Chin SF, Russell R, Baumbusch LO, Caldas C, Borresen-Dale AL, Lingjaerde OC (2012)
    Copynumber: Efficient algorithms for single- and multi-track copy number segmentation
    BMC Genomics, 13, 591
    DOI 10.1186/1471-2164-13-591
  16. Oksvold MP, Pedersen NM, Forfang L, Smeland EB (2012)
    Effect of cycloheximide on epidermal growth factor receptor trafficking and signaling
    FEBS Lett., 586 (20), 3575-3581
    DOI 10.1016/j.febslet.2012.08.022
  17. Schmitz R, Young RM, Ceribelli M, Jhavar S, Xiao WM, Zhang MZ, Wright G, Shaffer AL, Hodson DJ, Buras E, Liu XL, Powell J, Yang YD, Xu WH, Zhao H, Kohlhammer H, Rosenwald A, Kluin P, Muller-Hermelink HK, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES et al. (2012)
    Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
    Nature, 490 (7418), 116-120
    DOI 10.1038/nature11378
  18. Sioud M, Mobergslien A (2012)
    Efficient siRNA Targeted Delivery into Cancer Cells by Gastrin-Releasing Peptides
    Bioconjugate Chem., 23 (5), 1040-1049
    DOI 10.1021/bc300050j
  19. Sioud M, Mobergslien A (2012)
    Selective killing of cancer cells by peptide-targeted delivery of an anti-microbial peptide
    Biochem. Pharmacol., 84 (9), 1123-1132
    DOI 10.1016/j.bcp.2012.08.002
  20. Tekle C, Nygren MK, Chen YW, Dybsjord I, Nesland JM, Maelandsmo GM, Fodstad O (2012)
    B7-H3 contributes to the metastatic capacity of melanoma cells by modulation of known metastasis-associated genes
    Int. J. Cancer, 130 (10), 2282-2290
    DOI 10.1002/ijc.26238
  21. Wahlin BE, Yri OE, Kimby E, Holte H, Delabie J, Smeland EB, Sundstrom C, Christensson B, Sander B (2012)
    Clinical significance of the WHO grades of follicular lymphoma in a population-based cohort of 505 patients with long follow-up times
    Br. J. Haematol., 156 (2), 225-233
    DOI 10.1111/j.1365-2141.2011.08942.x
  22. Yri OE, Ekstrom PO, Hilden V, Gaudernack G, Liestol K, Smeland EB, Holte H (2012)
    Polymorphisms in genes encoding interleukin-10 and drug metabolizing enzymes GSTP1, GSTT1, GSTA1 and UGT1A1 influence risk and outcome in Hodgkin lymphoma
    Leuk. Lymphoma, 53 (10), 1934-1944
    DOI 10.3109/10428194.2012.682307

Publications 2011

  1. Alizadeh AA, Gentles AJ, Alencar AJ, Liu CL, Kohrt HE, Houot R, Goldstein MJ, Zhao SC, Natkunam Y, Advani RH, Gascoyne RD, Briones J, Tibshirani RJ, Myklebust JH, Plevritis SK, Lossos IS, Levy R (2011)
    Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment
    Blood, 118 (5), 1350-1358
    DOI 10.1182/blood-2011-03-345272
  2. Almasbak H, Rian E, Hoel HJ, Pule M, Walchli S, Kvalheim G, Gaudernack G, Rasmussen AM (2011)
    Transiently redirected T cells for adoptive transfer
    Cytotherapy, 13 (5), 629-640
    DOI 10.3109/14653249.2010.542461
  3. Brunsvig PF, Kyte JA, Kersten C, Sundstrum S, Muller M, Nyakas M, Hansen GL, Gaudernack G, Aamdal S (2011)
    Telomerase Peptide Vaccination in NSCLC: A Phase II Trial in Stage III Patients Vaccinated after Chemoradiotherapy and an 8-Year Update on a Phase I/II Trial
    Clin. Cancer Res., 17 (21), 6847-6857
    DOI 10.1158/1078-0432.CCR-11-1385
  4. Corthay A, Lorvik KB, Bogen B (2011)
    Is Secretion of Tumour-specific Antigen Important for Cancer Eradication by CD4(+) T Cells? - Implications for Cancer Immunotherapy by Adoptive T Cell Transfer
    Scand. J. Immunol., 73 (6), 527-530
    DOI 10.1111/j.1365-3083.2011.02558.x
  5. Eide MB, Lauritzsen GF, Kvalheim G, Kolstad A, Fagerli UM, Maisenholder M, Ostenstad B, Fluge O, Delabie J, Aarset H, Liestol K, Holte H (2011)
    High dose chemotherapy with autologous stem cell support for patients with histologically transformed B-cell non-Hodgkin lymphomas. A Norwegian multi centre phase II study
    Br. J. Haematol., 152 (5), 600-610
    DOI 10.1111/j.1365-2141.2010.08519.x
  6. Hunger RE, Lang KK, Markowski CJ, Trachsel S, Moller M, Eriksen JA, Rasmussen AM, Braathen LR, Gaudernack G (2011)
    Vaccination of patients with cutaneous melanoma with telomerase-specific peptides
    Cancer Immunol. Immunother., 60 (11), 1553-1564
    DOI 10.1007/s00262-011-1061-z
  7. Huse K, Bakkebo M, Oksvold MP, Forfang L, Hilden VI, Stokke T, Smeland EB, Myklebust JH (2011)
    Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: Differential effects of BMP-6 and BMP-7
    Eur. J. Immunol., 41 (11), 3135-3145
    DOI 10.1002/eji.201141558
  8. Josefsen D, Forfang L, Dyrhaug M, Blystad AK, Stokke T, Smeland EB, Kvalheim G (2011)
    Side population cells in highly enriched CD34-positive cells from peripheral blood progenitor cells identify an immature subtype of hematopoietic progenitor cells but do not predict time to engraftment in patients treated with high-dose therapy
    Eur. J. Haematol., 87 (6), 494-502
    DOI 10.1111/j.1600-0609.2011.01681.x
  9. Kyte JA, Gaudernack G, Dueland S, Trachsel S, Julsrud L, Aamdal S (2011)
    Telomerase Peptide Vaccination Combined with Temozolomide: A Clinical Trial in Stage IV Melanoma Patients
    Clin. Cancer Res., 17 (13), 4568-4580
    DOI 10.1158/1078-0432.CCR-11-0184
  10. Malumbres R, Fresquet V, Roman-Gomez J, Bobadilla M, Robles EF, Altobelli GG, Calasanz MJ, Smeland EB, Aznar MA, Agirre X, Martin-Palanco V, Prosper F, Lossos IS, Martinez-Climent JA (2011)
    LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome
    Haematol-Hematol. J., 96 (7), 980-986
    DOI 10.3324/haematol.2011.040568
  11. Ngo VN, Young RM, Schmitz R, Jhavar S, Xiao WM, Lim KH, Kohlhammer H, Xu WH, Yang YD, Zhao H, Shaffer AL, Romesser P, Wright G, Powell J, Rosenwald A, Muller-Hermelink HK, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Fisher RI et al. (2011)
    Oncogenically active MYD88 mutations in human lymphoma
    Nature, 470 (7332), 115-U133
    DOI 10.1038/nature09671
  12. Sioud M (2011)
    New Insights into Mesenchymal Stromal Cell-Mediated T-Cell Suppression Through Galectins
    Scand. J. Immunol., 73 (2), 79-84
    DOI 10.1111/j.1365-3083.2010.02491.x
  13. Sioud M, Mobergslien A, Boudabous A, Floisand Y (2011)
    Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins
    Int. J. Oncol., 38 (2), 385-390
    DOI 10.3892/ijo.2010.869
  14. Suso EMI, Dueland S, Rasmussen AM, Vetrhus T, Aamdal S, Kvalheim G, Gaudernack G (2011)
    hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
    Cancer Immunol. Immunother., 60 (6), 809-818
    DOI 10.1007/s00262-011-0991-9
  15. Tkacz-Stachowska K, Lund-Andersen C, Velissarou A, Myklebust JH, Stokke T, Syljuasen RG (2011)
    The amount of DNA damage needed to activate the radiation-induced G2 checkpoint varies between single cells
    Radiother. Oncol., 101 (1), 24-27
    DOI 10.1016/j.radonc.2011.05.060
  16. Torfoss D, Sandstad B, Mollnes TE, Hoiby EA, Holte H, Bjerner J, Bjoro T, Gaudernack G, Kvalheim G, Kvaloy S (2011)
    The Mild Inflammatory Response in Febrile Neutropenic Lymphoma Patients with Low Risk of Complications is More Pronounced in Patients Receiving Tobramycin Once Daily Compared with Three Times Daily
    Scand. J. Immunol., 74 (6), 632-639
    DOI 10.1111/j.1365-3083.2011.02618.x
  17. Walchli B, Loset GA, Kumari S, Johansen JN, Yang WW, Sandlie I, Olweus J (2011)
    A Practical Approach to T-Cell Receptor Cloning and Expression
    PLoS One, 6 (11), e27930
    DOI 10.1371/journal.pone.0027930

Publications 2010

  1. Abraham D, Zins K, Sioud M, Lucas T, Schafer R, Stanley ER, Aharinejad S (2010)
    Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma
    Int. J. Cancer, 126 (6), 1339-1352
    DOI 10.1002/ijc.24859
  2. Abrahamsen IW, Stronen E, Walchli S, Johansen JN, Kjellevoll S, Kumari S, Komada M, Gaudernack G, Tjonnfjord G, Toebes M, Schumacher TN, Lund-Johansen F, Olweus J (2010)
    Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif
    Leukemia, 24 (11), 1901-1909
    DOI 10.1038/leu.2010.186
  3. Bakkebo M, Huse K, Hilden VI, Smeland EB, Oksvold MP (2010)
    TGF-beta-induced growth inhibition in B-cell lymphoma correlates with Smad1/5 signalling and constitutively active p38 MAPK
    BMC Immunol., 11, 57
    DOI 10.1186/1471-2172-11-57
  4. Boe S, Saeboe-Larssen S, Hovig E (2010)
    Light-Induced Gene Expression Using Messenger RNA Molecules
    Oligonucleotides, 20 (1), 1-6
    DOI 10.1089/oli.2009.0209
  5. Chao MP, Alizadeh AA, Tang C, Myklebust JH, Varghese B, Gill S, Jan M, Cha AC, Chan CK, Tan BT, Park CY, Zhao FF, Kohrt HE, Malumbres R, Briones J, Gascoyne RD, Lossos IS, Levy R, Weissman IL, Majeti R (2010)
    Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma
    Cell, 142 (5), 699-713
    DOI 10.1016/j.cell.2010.07.044
  6. Davis RE, Ngo VN, Lenz G, Tolar P, Young RM, Romesser PB, Kohlhammer H, Lamy L, Zhao H, Yang YD, Xu WH, Shaffer AL, Wright G, Xiao WM, Powell J, Jiang JK, Thomas CJ, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Johnson NA, Rimsza LM, Campo E et al. (2010)
    Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
    Nature, 463 (7277), 88-U97
    DOI 10.1038/nature08638
  7. Eide MB, Liestol K, Lingjaerde OC, Hystad ME, Kresse SH, Meza-Zepeda L, Myklebost O, Troen G, Aamot HV, Holte H, Smeland EB, Delabie J (2010)
    Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones
    Blood, 116 (9), 1489-1497
    DOI 10.1182/blood-2010-03-272278
  8. Fredriksen L, Mathiesen G, Sioud M, Eijsink VGH (2010)
    Cell Wall Anchoring of the 37-Kilodalton Oncofetal Antigen by Lactobacillus plantarum for Mucosal Cancer Vaccine Delivery
    Appl. Environ. Microbiol., 76 (21), 7359-7362
    DOI 10.1128/AEM.01031-10
  9. Iversen PO, Sorensen DR, Sioud M (2010)
    A combined immunostimulatory and immunoinhibitory short interference RNA reduces hypercoagulability in a rat model of acute promyelocytic leukaemia
    Thromb. Haemost., 104 (2), 350-354
    DOI 10.1160/TH09-12-0816
  10. Rasmussen AM, Borelli G, Hoel HJ, Lislerud K, Gaudernack G, Kvalheim G, Aarvak T (2010)
    Ex vivo expansion protocol for human tumor specific T cells for adoptive T cell therapy
    J. Immunol. Methods, 355 (1-2), 52-60
    DOI 10.1016/j.jim.2010.02.004
  11. Rui LX, Emre NCT, Kruhlak MJ, Chung HJ, Steidl C, Slack G, Wright GW, Lenz G, Ngo VN, Shaffer AL, Xu WH, Zhao H, Yang YD, Lamy L, Davis RE, Xiao WM, Powell J, Maloney D, Thomas CJ, Moller P, Rosenwald A, Ott G, Muller-Hermelink HK, Savage K, Connors JM et al. (2010)
    Cooperative Epigenetic Modulation by Cancer Amplicon Genes
    Cancer Cell, 18 (6), 590-605
    DOI 10.1016/j.ccr.2010.11.013
  12. Sanner H, Kirkhus E, Merckoll E, Tollisen A, Roisland M, Lie BA, Taraldsrud E, Gran JT, Flato B (2010)
    Long-Term Muscular Outcome and Predisposing and Prognostic Factors in Juvenile Dermatomyositis: A Case-Control Study
    Arthritis Care Res., 62 (8), 1103-1111
    DOI 10.1002/acr.20203
  13. Sioud M (2010)
    Recent advances in small interfering RNA sensing by the immune system
    New Biotech., 27 (3), 236-242
    DOI 10.1016/j.nbt.2010.02.015
  14. Sioud M, Mobergslien A, Boudabous A, Floisand Y (2010)
    Evidence for the Involvement of Galectin-3 in Mesenchymal Stem Cell Suppression of Allogeneic T-Cell Proliferation
    Scand. J. Immunol., 71 (4), 267-274
    DOI 10.1111/j.1365-3083.2010.02378.x
  15. Szczepanowicz K, Hoel HJ, Szyk-Warszynska L, Bielanska E, Bouzga AM, Gaudernack G, Simon C, Warszynski P (2010)
    Formation of Biocompatible Nanocapsules with Emulsion Core and Pegylated Shell by Polyelectrolyte Multi layer Adsorption
    Langmuir, 26 (15), 12592-12597
    DOI 10.1021/la102061s
  16. Yamazaki T, Walchli S, Fujita T, Ryser S, Hoshijima M, Schlegel W, Kuroda S, Maturana AD (2010)
    Splice variants of Enigma homolog, differentially expressed during heart development, promote or prevent hypertrophy
    Cardiovasc. Res., 86 (3), 374-382
    DOI 10.1093/cvr/cvq023

Publications 2009

  1. Copier J, Dalgleish AG, Britten CM, Finke LH, Gaudernack G, Gnjatic S, Kallen K, Kiessling R, Schuessler-Lenz M, Singh H, Talmadge J, Zwierzina H, Hakansson L (2009)
    Improving the efficacy of cancer immunotherapy
    Eur. J. Cancer, 45 (8), 1424-1431
    DOI 10.1016/j.ejca.2008.12.017
  2. Corthay A, Lundin KU, Lorvik KB, Hofgaard PO, Bogen B (2009)
    Secretion of Tumor-Specific Antigen by Myeloma Cells Is Required for Cancer Immunosurveillance by CD4(+) T Cells
    Cancer Res., 69 (14), 5901-5907
    DOI 10.1158/0008-5472.CAN-08-4816
  3. Flatekval GF, Sioud M (2009)
    Modulation of dendritic cell maturation and function with mono- and bifunctional small interfering RNAs targeting indoleamine 2,3-dioxygenase
    Immunology, 128 (1), e837-e848
    DOI 10.1111/j.1365-2567.2009.03093.x
  4. Gao QL, Geng L, Kvalheim G, Gaudernack G, Suo ZH (2009)
    Identification of Cancer Stem-like Side Population Cells in Ovarian Cancer Cell Line OVCAR-3
    Ultrastruct. Pathol., 33 (4), PII 914188460-181
    DOI 10.1080/01913120903086072
  5. Hauge H, Fjelland KE, Sioud M, Aasheim HC (2009)
    Evidence for the involvement of FAM110C protein in cell spreading and migration
    Cell. Signal., 21 (12), 1866-1873
    DOI 10.1016/j.cellsig.2009.08.001
  6. Houot R, Goldstein MJ, Kohrt HE, Myklebust JH, Alizadeh AA, Lin JT, Irish JM, Torchia JA, Kolstad A, Chen LP, Levy R (2009)
    Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T-reg depletion
    Blood, 114 (16), 3431-3438
    DOI 10.1182/blood-2009-05-223958
  7. Hov H, Tian E, Holien T, Holt RU, Vatsveen TK, Fagerli UM, Waage A, Borset M, Sundan A (2009)
    c-Met signaling promotes IL-6-induced myeloma cell proliferation
    Eur. J. Haematol., 82 (4), 277-287
    DOI 10.1111/j.1600-0609.2009.01212.x
  8. Iversen PO, Semaeva E, Sorensen DR, Wiig H, Sioud M (2009)
    Dendritic Cells Loaded with Tumor Antigens and a Dual Immunostimulatory and Anti-Interleukin 10-Specific Small Interference RNA Prime T Lymphocytes against Leukemic Cells
    Transl. Oncol., 2 (4), 242-246
    DOI 10.1593/tlo.09154
  9. Kyte JA (2009)
    Cancer vaccination with telomerase peptide GV1001
    Expert Opin. Investig. Drugs, 18 (5), 687-694
    DOI 10.1517/13543780902897631
  10. Kyte JA, Trachsel S, Risberg B, Straten PT, Lislerud K, Gaudernack G (2009)
    Unconventional cytokine profiles and development of T cell memory in long-term survivors after cancer vaccination
    Cancer Immunol. Immunother., 58 (10), 1609-1626
    DOI 10.1007/s00262-009-0670-2
  11. Nygren MK, Dosen-Dahl G, Stubberud H, Walchli S, Munthe E, Rian E (2009)
    beta-catenin is involved in N-cadherin-dependent adhesion, but not in canonical Wnt signaling in E2A-PBX1-positive B acute lymphoblastic leukemia cells
    Exp. Hematol., 37 (2), 225-233
    DOI 10.1016/j.exphem.2008.10.007
  12. O'Riain C, O'Shea DM, Yang Y, Le Dieu R, Gribben JG, Summers K, Yeboah-Afari J, Bhaw-Rosun L, Fleischmann C, Mein CA, Crook T, Smith P, Kelly G, Rosenwald A, Ott G, Campo E, Rimsza LM, Smeland EB, Chan WC, Johnson N, Gascoyne RD, Reimer S, Braziel RM, Wright GW, Staudt LM et al. (2009)
    Array-based DNA methylation profiling in follicular lymphoma
    Leukemia, 23 (10), 1858-1866
    DOI 10.1038/leu.2009.114
  13. Rolle A, Olweus J (2009)
    Dendritic cells in cytomegalovirus infection: viral evasion and host countermeasures
    APMIS, 117 (5-6), 413-426
    DOI 10.1111/j.1600-0463.2009.02449.x
  14. Sioud M (2009)
    Does our Current Understanding of Immune Tolerance, Autoimmunity, and Immunosuppressive Mechanisms Facilitate the Design of Efficient Cancer Vaccines?
    Scand. J. Immunol., 70 (6), 516-525
    DOI 10.1111/j.1365-3083.2009.02326.x
  15. Sioud M, Boudabous A, Cekaite L (2009)
    Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs
    Int. J. Mol. Med., 23 (1), 33-39
    DOI 10.3892/ijmm_00000098
  16. Sioud M, Floisand Y (2009)
    NOD2/CARD15 on bone marrow CD34+hematopoietic cells mediates induction of cytokines and cell differentiation
    J. Leukoc. Biol., 85 (6), 939-946
    DOI 10.1189/jlb.1008650
  17. Skanland SS, Walchli S, Brech A, Sandvig K (2009)
    SNX4 in Complex with Clathrin and Dynein: Implications for Endosome Movement
    PLoS One, 4 (6), e5935
    DOI 10.1371/journal.pone.0005935
  18. Skanland SS, Walchli S, Sandvig K (2009)
    beta-arrestins attenuate p38-mediated endosome to Golgi transport
    Cell Microbiol., 11 (5), 796-807
    DOI 10.1111/j.1462-5822.2009.01292.x
  19. Stronen E, Abrahamsen IW, Gaudernack G, WAlchli S, Munthe E, Buus S, Johansen FE, Lund-Johansen F, Olweus J (2009)
    Dendritic Cells Engineered to Express Defined Allo-HLA Peptide Complexes Induce Antigen-specific Cytotoxic T Cells Efficiently Killing Tumour Cells
    Scand. J. Immunol., 69 (4), 319-328
    DOI 10.1111/j.1365-3083.2008.02223.x
  20. Walchli S, Aasheim HC, Skanland SS, Spilsberg B, Torgersen ML, Rosendal KR, Sandvig K (2009)
    Characterization of clathrin and Syk interaction upon Shiga toxin binding
    Cell. Signal., 21 (7), 1161-1168
    DOI 10.1016/j.cellsig.2009.03.005

Publications 2008

  1. Abraham D, Zins K, Sioud M, Lucas T, Aharinejad S (2008)
    Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts
    Front. Biosci., 13, 5571-5579
  2. Alsoe L, Stacy JE, Fossa A, Funderad S, Brekke OH, Gaudernack G (2008)
    Identification of prostate cancer antigens by automated high-throughput filter immunoscreening
    J. Immunol. Methods, 330 (1-2), 12-23
    DOI 10.1016/j.jim.2007.10.011
  3. Chekenya M, Krakstad C, Svendsen A, Netland IA, Staalesen V, Tysnes BB, Selheim F, Wang J, Sakariassen PO, Sandal T, Lonning PE, Flatmark T, Enger PO, Bjerkvig R, Sioud M, Stallcup WB (2008)
    The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling
    Oncogene, 27 (39), 5182-5194
    DOI 10.1038/onc.2008.157
  4. Dosen-Dahl G, Munthe E, Nygren MK, Stubberud H, Hystad ME, Rian E (2008)
    Bone marrow stroma cells regulate TIEG1 expression in acute lymphoblastic leukemia cells: Role of TGF beta/BMP-6 and TIEG1 in chemotherapy escape
    Int. J. Cancer, 123 (12), 2759-2766
    DOI 10.1002/ijc.23833
  5. Furset G, Floisand Y, Sioud M (2008)
    Impaired expression of indoleamine 2, 3-dioxygenase in monocyte-derived dendritic cells in response to Toll-like receptor-7/8 ligands
    Immunology, 123 (2), 263-271
    DOI 10.1111/j.1365-2567.2007.02695.x
  6. Kloster MM, Hafte TT, Moltzau LR, Naderi EH, Dahle MK, Skalhegg BS, Gaudernack G, Levy FO, Naderi S, Blomhoff HK (2008)
    EBV infection renders B cells resistant to growth inhibition via adenylyl cyclase
    Cell. Signal., 20 (6), 1169-1178
    DOI 10.1016/j.cellsig.2008.02.007
  7. Lenz G, Davis RE, Ngo VN, Lam L, George TC, Wright GW, Dave SS, Zhao H, Xu WH, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Fisher RI, Chan WC, Staudt LM (2008)
    Oncogenic CARD11 mutations in human diffuse large B cell lymphoma
    Science, 319 (5870), 1676-1679
    DOI 10.1126/science.1153629
  8. Lenz G, Wright G, Dave SS, Xiao W, Powell J, Zhao H, Xu W, Tan B, Goldschmidt N, Iqbal J, Vose J, Bast M, Fu K, Weisenburger DD, Greiner TC, Armitage JO, Kyle A, May L, Gascoyne RD, Connors JM, Troen G, Holte H, Kvaloy S, Dierickx D, Verhoef G et al. (2008)
    Stromal Gene Signatures in Large-B-Cell Lymphomas
    N. Engl. J. Med., 359 (22), 2313-2323
    DOI 10.1056/NEJMoa0802885
  9. Lenz G, Wright GW, Emre NCT, Kohlhammer H, Dave SS, Davis RE, Carty S, Lam LT, Shaffer AL, Xiao WM, Powell J, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Campo E, Jaffe ES, Delabie J, Smeland EB, Rimsza LM, Fisher RI, Weisenburger DD, Chan WC, Staudt LM (2008)
    Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways
    Proc. Natl. Acad. Sci. U. S. A., 105 (36), 13520-13525
    DOI 10.1073/pnas.0804295105
  10. O'Shea D, O'Riain C, Taylor C, Waters R, Carlotti E, MacDougall F, Gribben J, Rosenwald A, Ott G, Rimsza LM, Smeland EB, Johnson N, Campo E, Greiner TC, Chan WC, Gascoyne RD, Wright G, Staudt LM, Lister TA, Fitzgibbon J (2008)
    The presence of TP53 mutation at diagnosis of follicular lymphoma identifies a high-risk group of patients with shortened time to disease progression and poorer overall survival
    Blood, 112 (8), 3126-3129
    DOI 10.1182/blood-2008-05-154013
  11. Shadidi M, Sorensen D, Dybwad A, Furset G, Sioud M (2008)
    Mucosal vaccination with phage-displayed tumour antigens identified through proteomics-based strategy inhibits the growth and metastasis of 4T1 breast adenocarcinoma
    Int. J. Oncol., 32 (1), 241-247
  12. Sioud M (2008)
    Does the understanding of immune activation by RNA predict the design of safe siRNAs?
    Front. Biosci., 13, 4379-4392
    DOI 10.2741/3011
  13. Sorensen V, Zhen Y, Zakrzewska M, Haugsten EM, Walchli S, Nilsen T, Olsnes S, Wiedlocha A (2008)
    Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus
    Mol. Cell. Biol., 28 (12), 4129-4141
    DOI 10.1128/MCB.02117-07
  14. Walchli S, Sioud M (2008)
    Vector-based delivery of siRNAs: In vitro and in vivo challenges
    Front. Biosci., 13, 3488-3493
  15. Wester T, Jorgensen JJ, Stranden E, Sandbaek G, Tjonnfjord G, Bay D, Kolleros D, Kroese AJ, Brinchmann JE (2008)
    Treatment with autologous bone marrow mononuclear cells in patients with critical lower limb ischaemia. A pilot study
    Scand. J. Surg., 97 (1), 56-62
    DOI 10.1177/145749690809700108
  16. Wierod L, Rosseland CM, Lindeman B, Oksvold MP, Grosvik H, Skarpen E, Huitfeldt HS (2008)
    Activation of the p53-p21(Cip1) pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes
    Oncogene, 27 (19), 2763-2771
    DOI 10.1038/sj.onc.1210937

Publications 2007

  1. Cabezon T, Celis JE, Skibshoj I, Klingelhofer J, Grigorian M, Gromov P, Rank F, Myklebust JH, Maelandsmo GM, Lukanidin E, Ambartsumian N (2007)
    Expression of S100A4 by, a variety of cell types present in the tumor microenvironment of human breast cancer
    Int. J. Cancer, 121 (7), 1433-1444
    DOI 10.1002/ijc.22850
  2. Cekaite L, Furset G, Hovig E, Sioud M (2007)
    Gene expression analysis in blood cells in response to unmodified and 2 '-modified siRNAs reveals TLR-dependent and independent effects
    J. Mol. Biol., 365 (1), 90-108
    DOI 10.1016/j.jmb.2006.09.034
  3. Furset G, Sioud M (2007)
    Design of bifunctional siRNAs: Combining immunostimulation and gene-silencing in one single siRNA molecule
    Biochem. Biophys. Res. Commun., 352 (3), 642-649
    DOI 10.1016/j.bbrc.2006.11.059
  4. Hystad ME, Myklebust JH, Bo TH, Sivertsen EA, Rian E, Forfang L, Munthe E, Rosenwald A, Chiorazzi M, Jonassen I, Staudt LM, Smeland EB (2007)
    Characterization of early stages of human B cell development by gene expression profiling
    J. Immunol., 179 (6), 3662-3671
    DOI 10.4049/jimmunol.179.6.3662
  5. Jarnjak-Jankovic S, Hammerstad H, Saeboe-Larssen S, Kvalheim G, Gaudernack G (2007)
    A full scale comparative study of methods for generation of functional Dendritic cells for use as cancer vaccines
    BMC Cancer, 7, 119
    DOI 10.1186/1471-2407-7-119
  6. Jarnjak-Jankovic S, Saeboe-Larssen S, Kvalheim G, Gaudernack G (2007)
    MRNA transfection of DC in the immature or mature state: comparable in vitro priming of Th and cytotoxic T lymphocytes against DC electroporated with tumor cell line-derived mRNA
    Cytotherapy, 9 (6), 587-592
    DOI 10.1080/14653240701466354
  7. Kyte JA, Kvalheim G, Lislerud K, Straten PT, Dueland S, Aamdal S, Gaudernack G (2007)
    T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
    Cancer Immunol. Immunother., 56 (5), 659-675
    DOI 10.1007/s00262-006-0222-y
  8. Lenz G, Nagel I, Siebert R, Roschke AV, Sanger W, Wright GW, Dave SS, Tan B, Zhao H, Rosenwald A, Muller-Hermelink HK, Gascoyne RD, Campo E, Jaffe ES, Smeland EB, Fisher RI, Kuehl WM, Chan WC, Staudt LM (2007)
    Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma
    J. Exp. Med., 204 (3), 633-643
    DOI 10.1084/jem.20062041
  9. Nygren MK, Dosen G, Hystad ME, Stubberud H, Funderud S, Rian E (2007)
    Wnt3A activates canonical Wnt signalling in acute lymphoblastic leukaemia (ALL) cells and inhibits the proliferation of B-ALL cell lines
    Br. J. Haematol., 136 (3), 400-413
    DOI 10.1111/j.1365-2141.2006.06442.x
  10. Sioud M (2007)
    RNA interference and innate immunity
    Adv. Drug Deliv. Rev., 59 (2-3), 153-163
    DOI 10.1016/j.addr.2007.03.006
  11. Sioud M, Floisand Y (2007)
    TLR agonists induce the differentiation of human bone marrow CD34(+) progenitors into CD11c(+) CD80/86(+) DC capable of inducing a Th1-type response
    Eur. J. Immunol., 37 (10), 2834-2846
    DOI 10.1002/eji.200737112
  12. Sioud M, Furset G, Cekaite L (2007)
    Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
    Biochem. Biophys. Res. Commun., 361 (1), 122-126
    DOI 10.1016/j.bbrc.2007.06.177
  13. Sivertsen EA, Huse K, Hystad ME, Kersten C, Smeland EB, Myklebust JH (2007)
    Inhibitory effects and target genes of bone morphogenetic protein 6 in Jurkat TAg cells
    Eur. J. Immunol., 37 (10), 2937-2948
    DOI 10.1002/eji.200636759
  14. Wiestner A, Tehrani M, Chiorazzi M, Wright G, Gibellini F, Nakayama K, Liu H, Rosenwald A, Muller-Hermelink HK, Ott G, Chan WC, Greiner TC, Weisenburger DD, Vose J, Armitage JO, Gascoyne RD, Connors JM, Campo E, Montserrat E, Bosch F, Smeland EB, Kvaloy S, Holte H, Delabie J, Fisher RI et al. (2007)
    Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival
    Blood, 109 (11), 4599-4606
    DOI 10.1182/blood-2006-08-039859
  15. Zins K, Abraham D, Sioud M, Aharinejad S (2007)
    Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway
    Cancer Res., 67 (3), 1038-1045
    DOI 10.1158/0008-5472.CAN-06-2295
  16. Aamot HV, Torlakovic EE, Eide MB, Holte H, Heim S (2007)
    Non-Hodgkin lymphoma with t(14;18): clonal evolution patterns and cytogenetic-pathologic-clinical correlations
    J. Cancer Res. Clin. Oncol., 133 (7), 455-470
    DOI 10.1007/s00432-006-0188-3

Publications 2006

  1. Angell-Petersen E, Spetalen S, Madsen SJ, Sun CH, Peng Q, Carper SW, Sioud M, Hirschberg H (2006)
    Influence of light fluence rate on the effects of photodynamic therapy in an orthotopic rat glioma model
    J. Neurosurg., 104 (1), 109-117
    DOI 10.3171/jns.2006.104.1.109
  2. Bernhardt SL, Gjertsen MK, Trachsel S, Moller M, Eriksen JA, Meo M, Buanes T, Gaudernack G (2006)
    Telomerase peptide vaccination of patients with non-resectable pancreatic cancer: a dose escalating phase I/II study
    Br. J. Cancer, 95 (11), 1474-1482
    DOI 10.1038/sj.bjc.6603437
  3. Brunsvig PF, Aamdal S, Gjertsen MK, Kvalheim G, Markowski-Grimsrud CJ, Sve I, Dyrhaug M, Trachsel S, Moller M, Eriksen JA, Gaudernack G (2006)
    Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
    Cancer Immunol. Immunother., 55 (12), 1553-1564
    DOI 10.1007/s00262-006-0145-7
  4. Dave SS, Fu K, Wright GW, Lam LT, Kluin P, Boerma EJ, Greiner TC, Weisenburger DD, Rosenwald A, Ott G, Muller-Hermelink H, Gascoyne RD, Delabie J, Rimsza LM, Braziel RM, Grogan TM, Campo E, Jaffe ES, Dave BJ, Sanger W, Bast M, Vose JM, Armitage JO, Connors JM, Smeland EB et al. (2006)
    Molecular diagnosis of Burkitt's lymphoma
    N. Engl. J. Med., 354 (23), 2431-2442
    DOI 10.1056/NEJMoa055759
  5. Dosen G, Tenstad E, Nygren MK, Stubberud H, Funderud S, Rian E (2006)
    Wnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesis
    BMC Immunol., 7, 13
    DOI 10.1186/1471-2172-7-13
  6. Huynh T, Walchli S, Sioud M (2006)
    Transcriptional targeting of small interfering RNAs into cancer cells
    Biochem. Biophys. Res. Commun., 350 (4), 854-859
    DOI 10.1016/j.bbrc.2006.09.127
  7. Ji ZY, Yang GR, Shahzidi S, Tkacz-Stachowska K, Suo ZH, Nesland JM, Peng Q (2006)
    Induction of hypoxia-inducible factor-1 alpha overexpression by cobalt chloride enhances cellular resistance to photodynamic therapy
    Cancer Lett., 244 (2), 182-189
    DOI 10.1016/j.canlet.2005.12.010
  8. Kersten C, Dosen G, Myklebust JH, Sivertsen EA, Hystad ME, Smeland EB, Rian E (2006)
    BMP-6 inhibits human bone marrow B lymphopoiesis - Upregulation of Id1 and Id3
    Exp. Hematol., 34 (1), 72-81
    DOI 10.1016/j.exphem.2005.09.010
  9. Kyte JA, Gaudernack G (2006)
    Immuno-gene therapy of cancer with tumour-mRNA transfected dendritic cells
    Cancer Immunol. Immunother., 55 (11), 1432-1442
    DOI 10.1007/s00262-006-0161-7
  10. Kyte JA, Mu L, Aamdal S, Kvalheim G, Dueland S, Hauser M, Gullestad HP, Ryder T, Lislerud K, Hammerstad H, Gaudernack G (2006)
    Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
    Cancer Gene Ther., 13 (10), 905-918
    DOI 10.1038/sj.cgt.7700961
  11. Lunde K, Solheim S, Aakhus S, Arnesen H, Abdelnoor M, Egeland T, Endresen K, Ilebekk A, Mangschau A, Fjeld JG, Smith HJ, Taraldsrud E, Grogaard HK, Bjornerheim R, Brekke M, Muller C, Hopp E, Ragnarsson A, Brinchmann JE, Forfang K (2006)
    Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction
    N. Engl. J. Med., 355 (12), 1199-1209
    DOI 10.1056/NEJMoa055706
  12. Saeboe-Larssen S, Fossberg E, Gaudernack G (2006)
    Characterization of novel alternative splicing sites in human telomerase reverse transcriptase (hTERT): analysis of expression and mutual correlation in mRNA isoforms from normal and tumour tissues
    BMC Mol. Biol., 7, 26
    DOI 10.1186/1471-2199-7-26
  13. Sioud M (2006)
    RNAi therapy - Antibodies guide the way
    Gene Ther., 13 (3), 194-195
    DOI 10.1038/sj.gt.3302634
  14. Sioud M (2006)
    RNA interference below the immune radar
    Nat. Biotechnol., 24 (5), 521-522
    DOI 10.1038/nbt0506-521
  15. Sioud M (2006)
    Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: A central role for 2 '-hydroxyl uridines in immune responses
    Eur. J. Immunol., 36 (5), 1222-1230
    DOI 10.1002/eji.200535708
  16. Sioud M (2006)
    Innate sensing of self and non-self RNAs by Toll-like receptors
    Trends Mol. Med, 12 (4), 167-176
    DOI 10.1016/j.molmed.2006.02.004
  17. Sioud M, Floisand Y, Forfang U, Lund-Johansen F (2006)
    Signaling through toll-like receptor 7/8 induces the differentiation of human bone marrow CD34+progenitor cells along the myeloid lineage
    J. Mol. Biol., 364 (5), 945-954
    DOI 10.1016/j.jmb.2006.09.054
  18. Sioud M, Furset G (2006)
    Molecular basis for the immunostimulatory potency of small interfering RNAs
    J. Biomed. Biotechnol., 23429
    DOI 10.1155/JBB/2006/23429
  19. Sioud M, Haoudi A (2006)
    RNA interference
    J. Biomed. Biotechnol., 89018
    DOI 10.1155/JBB/2006/89018
  20. Sivertsen EA, Hystad ME, Gutzkow KB, Dosen G, Smeland EB, Blomhoff HK, Myklebust JH (2006)
    PI3K/Akt-dependent Epo-induced signalling and target genes in human early erythroid progenitor cells
    Br. J. Haematol., 135 (1), 117-128
    DOI 10.1111/j.1365-2141.2006.06252.x

Publications 2005

  1. Furre IE, Shahzidi S, Luksiene Z, Moller ATN, Borgen E, Morgan J, Tkacz-Stachowska K, Nesland JM, Peng Q (2005)
    Targeting PBR by hexaminolevulinate-mediated photodynamic therapy induces apoptosis through translocation of apoptosis-inducing factor in human leukemia cells
    Cancer Res., 65 (23), 11051-11060
    DOI 10.1158/0008-5472.CAN-05-0510
  2. Jarnjak-Jankovic S, Pettersen RD, Saeboe-Larssen S, Wesenberg F, Gaudernack G (2005)
    Evaluation of dendritic cells loaded with apoptotic cancer cells or expressing tumour mRNA as potential cancer vaccines against leukemia
    BMC Cancer, 5, 20
    DOI 10.1186/1471-2407-5-20
  3. Jarnjak-Jankovic S, Pettersen RD, Saeboe-Larssen S, Wesenberg F, Olafsen MRK, Gaudernack G (2005)
    Preclinical evaluation of autologous dendritic cells transfected with mRNA or loaded with apoptotic cells for immunotherapy of high-risk neuroblastoma
    Cancer Gene Ther., 12 (8), 699-707
    DOI 10.1038/sj.cgt.7700820
  4. Kersten C, Sivertsen EA, Hystad ME, Forfang L, Smeland EB, Myklebust JH (2005)
    BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1
    BMC Immunol., 6, 9
    DOI 10.1186/1471-2172-6-9
  5. Kyte JA, Kvalheim G, Aamdal S, Saeboe-Larssen S, Gaudernack G (2005)
    Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
    Cancer Gene Ther., 12 (6), 579-591
    DOI 10.1038/sj.cgt.7700837
  6. Mu LJ, Kyte JA, Kvalheim G, Aamdal S, Dueland S, Hauser M, Hammerstad H, Waehre H, Raabe N, Gaudernack G (2005)
    Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
    Br. J. Cancer, 93 (7), 749-756
    DOI 10.1038/sj.bjc.6602761
  7. Patzke S, Hauge H, Sioud M, Finne EF, Sivertsen EA, Delabie J, Stokke T, Hans-Christian A (2005)
    Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization
    Oncogene, 24 (7), 1159-1173
    DOI 10.1038/sj.onc.1208267
  8. Rosok O, Sioud M (2005)
    Systematic search for natural antisense transcripts in eukaryotes - (Review)
    Int. J. Mol. Med., 15 (2), 197-203
  9. Sioud M (2005)
    Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization
    J. Mol. Biol., 348 (5), 1079-1090
    DOI 10.1016/j.jmb.2005.03.013
  10. Sioud M, Iversen PO (2005)
    Ribozymes, DNAzymes and small interfering RNAs as therapeutics
    Curr. Drug Targets, 6 (6), 647-653
    DOI 10.2174/1389450054863653
  11. Torlakovic E, Malecka A, Myklebust JH, Tierens A, Aasheim HC, Nesland JM, Smeland E, Kvaloy S, Delabie J (2005)
    PU.1 protein expression has a positive linear association with protein expression of germinal centre B cell genes including BCL-6, CD10, CD20 and CD22: Identification of PU.1 putative binding sites in the BCL-6 promotor
    J. Pathol., 206 (3), 312-319
    DOI 10.1002/path.1777
  12. Torlakovic E, Tenstad E, Funderud S, Rian E (2005)
    CD10(+) stromal cells form B-lymphocyte maturation niches in the human bone marrow
    J. Pathol., 205 (3), 311-317
    DOI 10.1002/path.1705

Publications 2004

  1. Aharinejad S, Paulus P, Sioud M, Hofmann M, Zins K, Schafer R, Stanley ER, Abraham D (2004)
    Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice
    Cancer Res., 64 (15), 5378-5384
    DOI 10.1158/0008-5472.CAN-04-0961
  2. Breivik J, Gaudernack G (2004)
    Resolving the evolutionary paradox of genetic instability: a cost-benefit analysis of DNA repair in changing environments
    FEBS Lett., 563 (1-3), 7-12
    DOI 10.1016/S0014-5793(04)00282-0
  3. Cekaite L, Haug O, Myklebost O, Aldrin M, Ostenstad B, Holden M, Frigessi A, Hovig E, Sioud M (2004)
    Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
    Proteomics, 4 (9), 2572-2582
    DOI 10.1002/pmic.200300768
  4. Fossa A, Alsoe L, Crameri R, Funderud S, Gaudernack G, Smeland EB (2004)
    Serological cloning of cancer/testis antigens expressed in prostate cancer using cDNA phage surface display
    Cancer Immunol. Immunother., 53 (5), 431-438
    DOI 10.1007/s00262-003-0458-8
  5. Fossa A, Berner A, Fossa SD, Hernes E, Gaudernack G, Smeland EB (2004)
    NY-ESO-1 protein expression and humoral immune responses in prostate cancer
    Prostate, 59 (4), 440-447
    DOI 10.1002/pros.20025
  6. Hirschberg H, Madsen S, Angell-Petersen E, Peng Q, Sioud M, Sun CH, Sorensen DR (2004)
    Repetitive 5-aminolevulinic acid mediated photodynamic therapy of rat glioma
    P SOC PHOTO-OPT INS, 5312, 405-414
    DOI 10.1117/12.527395
  7. Kersten C, Delabie J, Gaudernack G, Smeland EB, Fossa A (2004)
    Analysis of the autoantibody repertoire in Burkitt's lymphoma patients: frequent response against the transcription factor ATF-2
    Cancer Immunol. Immunother., 53 (12), 1119-1126
    DOI 10.1007/s00262-004-0558-0
  8. Lazarova P, Lijun M, Hammerstad H, Nesland J, Gaudernack G, Kvalheim G (2004)
    Experimental attempt to introduce a vaccine therapy by using DC-developed from CD34+cells
    NATO SCI SER I LIFE, 361, 134
  9. Leirdal M, Shadidy M, Rosok O, Sioud M (2004)
    Identification of genes differentially expressed in breast cancer cell line SKBR3: Potential identification of new prognostic biomarkers
    Int. J. Mol. Med., 14 (2), 217-222
  10. Moe JF, Sivertsen E, van Thanh D (2004)
    Adapting email functionality for mobile terminals
    LECT NOTES COMPUT SC, 3283, 199-206
  11. Mu LJ, Lazarova P, Gaudernack G, Saeboe-Larssen S, Kvalheim G (2004)
    Development of a clinical grade procedure for generation of mRNA transfected dendritic cells from purified frozen CD34+blood progenitor cells
    Int. J. Immunopathol. Pharmacol., 17 (3), 255-263
    DOI 10.1177/039463200401700305
  12. Reppe S, Olstad OK, Rian E, Gautvik VT, Gautvik KM, Jemtland R (2004)
    Butyrate response factor 1 is regulated by parathyroid hormone and bone morphogenetic protein-2 in osteoblastic cells
    Biochem. Biophys. Res. Commun., 324 (1), 218-223
    DOI 10.1016/j.bbrc.2004.09.030
  13. Rosok O, Sioud M (2004)
    Systematic identification of sense-antisense transcripts in mammalian cells
    Nat. Biotechnol., 22 (1), 104-108
    DOI 10.1038/nbt925
  14. Sioud M (2004)
    Therapeutic siRNAs
    Trends Pharmacol. Sci., 25 (1), 22-28
    DOI 10.1016/j.tips.2003.11.006
  15. Sioud M (2004)
    Therapeutic potential of small interfering RNAs
    Drug Future, 29 (7), 741-750
    DOI 10.1358/dof.2004.029.07.854171
  16. Sioud M, Rosok O (2004)
    Profiling microRNA expression using sensitive cDNA probes and filter arrays
    Biotechniques, 37 (4), 574-+
    DOI 10.2144/04374ST01

Publications 2003

  1. Bjorheim J, Abrahamsen TW, Kristensen AT, Gaudernack G, Ekstrom PO (2003)
    Approach to analysis of single nucleotide polymorphisms by automated constant denaturant capillary electrophoresis
    Mutat. Res.-Fundam. Mol. Mech. Mutagen., 526 (1-2), 75-83
    DOI 10.1016/S0027-5107(03)00033-2
  2. Bjorheim J, Gaudernack G, Giercksky KE, Ekstrom PO (2003)
    Direct identification of all oncogenic mutants in KRAS exon 1 by cycling temperature capillary electrophoresis
    Electrophoresis, 24 (1-2), 63-69
    DOI 10.1002/elps.200390032
  3. Bjorheim J, Minarik M, Gaudernack G, Ekstrom PO (2003)
    Evaluation of denaturing conditions in analysis of DNA variants applied to multi-capillary electrophoresis instruments
    J. Sep. Sci., 26 (12-13), 1163-1168
    DOI 10.1002/jssc.200301521
  4. Dybwad A, Lambin P, Sioud M, Zouali M (2003)
    Probing the specificity of human myeloma proteins with a random peptide phage library
    Scand. J. Immunol., 57 (6), 583-590
    DOI 10.1046/j.1365-3083.2003.01254.x
  5. Gjertsen MK, Saeterdal I, Saeboe-Larssen S, Gaudernack G (2003)
    HLA-A3 restricted mutant ras specific cytotoxic T-lymphocytes induced by vaccination with T-helper epitopes
    J. Mol. Med., 81 (1), 43-50
    DOI 10.1007/s00109-002-0390-y
  6. Mu LJ, Gaudernack G, Saeboe-Larssen S, Hammerstad H, Tierens A, Kvalheim G (2003)
    A protocol for generation of clinical grade mRNA-transfected monocyte-derived dendritic cells for cancer vaccines
    Scand. J. Immunol., 58 (5), 578-586
    DOI 10.1046/j.1365-3083.2003.01333.x
  7. Olstad OK, Gautvik VT, Reppe S, Rian E, Jemtland R, Ohlsson C, Bruland OS, Gautvik KM (2003)
    Molecular heterogeneity in human osteosarcoma demonstrated by enriched mRNAs isolated by directional tag PCR subtraction cloning
    Anticancer Res., 23 (3B), 2201-2216
  8. Shadidi M, Sioud M (2003)
    Selective targeting of cancer cells using synthetic peptides
    Drug Resist. Update, 6 (6), 363-371
    DOI 10.1016/j.drup.2003.11.002
  9. Sioud M, Sorensen D (2003)
    Generation of an effective anti-tumor immunity after immunization with xenogeneic antigens
    Eur. J. Immunol., 33 (1), 38-45
    DOI 10.1002/immu.200390005
  10. Sioud M, Sorensen DR (2003)
    Cationic liposome-mediated delivery of siRNAs in adult mice
    Biochem. Biophys. Res. Commun., 312 (4), 1220-1225
    DOI 10.1016/j.bbrc.2003.11.057
  11. Sorensen DR, Leirdal M, Sioud M (2003)
    Gene silencing by systemic delivery of synthetic siRNAs in adult mice
    J. Mol. Biol., 327 (4), 761-766
    DOI 10.1016/S0022-2836(03)00181-5
  12. Taraldsrud E, Kvalheim G, Jorstad S, Stavem K, Aandahl GS (2003)
    A survey of therapeutic hemapheresis in Norway year 2000
    Transfus. Apher. Sci., 28 (2), 135-141
    DOI 10.1016/S1473-0502(03)00004-1
  13. Wabakken T, Rian E, Kveine M, Aasheim HC (2003)
    The human solute carrier SLC41A1 belongs to a novel eukaryotic subfamily with homology to prokaryotic MgtE Mg2+ transporters
    Biochem. Biophys. Res. Commun., 306 (3), 718-724
    DOI 10.1016/S0006-291X(03)01030-1

Publications 2002

  1. Bjorheim J, Gaudernack G, Ekstrom PO (2002)
    Melting gel techniques in single nucleotide polymorphism and mutation detection: From theory to automation
    J. Sep. Sci., 25 (10-11), 637-647
    DOI 10.1002/1615-9314(20020701)25:10/11<637::AID-JSSC637>3.0.CO;2-L
  2. Bjorheim J, Minarik M, Gaudernack G, Ekstrom PO (2002)
    Mutation detection in KRAS exon 1 by constant denaturant capillary electrophoresis in 96 parallel capillaries
    Anal. Biochem., 304 (2), 200-205
    DOI 10.1006/abio.2002.5629
  3. Ekstrom PO, Bjorheim J, Gaudernack G, Giercksky KE (2002)
    Population screening of single-nucleotide polymorphisms exemplified by analysis of 8000 alleles
    J. Biomol. Screen, 7 (6), 501-506
    DOI 10.1177/1087057102238623
  4. Fossa A, Lilleby W, Foss SD, Gaudernack G, Torlakovic G, Berner A (2002)
    Independent prognostic significance of Her-2 oncoprotein expression in pNO prostate cancer undergoing curative radiotherapy
    Int. J. Cancer, 99 (1), 100-105
    DOI 10.1002/ijc.10286
  5. Iversen PO, Emanuel PD, Sioud M (2002)
    Targeting Raf-1 gene expression by a DNA enzyme inhibits juvenile myelomonocytic leukemia cell growth
    Blood, 99 (11), 4147-4153
    DOI 10.1182/blood.V99.11.4147
  6. Kveine M, Tenstad E, Dosen G, Funderud S, Rian E (2002)
    Characterization of the novel human transmembrane protein 9 (TMEM9) that localizes to lysosomes and late endosomes
    Biochem. Biophys. Res. Commun., 297 (4), PII S0006-291X(02)02228-3-917
    DOI 10.1016/S0006-291X(02)02228-3
  7. Leirdal M, Sioud M (2002)
    Gene silencing in mammalian cells by preformed small RNA duplexes
    Biochem. Biophys. Res. Commun., 295 (3), PII S0006-291X(02)00736-2-748
    DOI 10.1016/S0006-291X(02)00736-2
  8. Machon O, Van Den Bout CJ, Backman M, Rosok O, Caubit X, Fromm SH, Geronimo B, Krauss S (2002)
    Forebrain-specific promoter/enhancer D6 derived from the mouse Dach1 gene controls expression in neural stem cells
    Neuroscience, 112 (4), PII S0306-4522(02)00053-2-966
    DOI 10.1016/S0306-4522(02)00053-2
  9. Paulsen JE, Bjorheim J, Roe J, Eide TJ, Alexander J, Gaudernack G (2002)
    Effect of vaccination with mutant KRAS peptides on rat colon carcinogenesis induced by azoxymethane
    Anticancer Res., 22 (1A), 171-175
  10. Saeboe-Larssen S, Fossberg E, Gaudernack G (2002)
    mRNA-based electrotransfection of human dendritic cells and induction of cytotoxic T lymphocyte responses against the telomerase catalytic subunit (hTERT)
    J. Immunol. Methods, 259 (1-2), 191-203
    DOI 10.1016/S0022-1759(01)00506-3
  11. Shadidi M, Sioud M (2002)
    Identification of novel carrier peptides for the specific delivery of therapeutics into cancer cells
    Faseb J., 16 (14), 256-+
    DOI 10.1096/fj.02-0280fje
  12. Sioud M (2002)
    How does autoimmunity cause tumor regression? A potential mechanism involving cross-reaction through epitope mimicry
    Mol. Med., 8 (3), 115-119
    DOI 10.1007/BF03402004
  13. Sorensen DR, Leirdal M, Iversen PO, Sioud M (2002)
    Combination of endostatin and a protein kinase C alpha DNA enzyme improves the survival of rats with malignant glioma
    Neoplasia, 4 (6), 474-479
    DOI 10.1038/sj.neo.7900271
  14. van den Bout CJ, Machon O, Rosok O, Backman M, Krauss S (2002)
    The mouse enhancer element D6 directs Cre recombinase activity in the neocortex and the hippocampus
    Mech. Dev., 110 (1-2), 179-182
    DOI 10.1016/S0925-4773(01)00597-4
  15. Wang JB, Delabie J, Aasheim HC, Smeland E, Myklebost O (2002)
    Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study
    BMC Bioinformatics, 3, 36
    DOI 10.1186/1471-2105-3-36

Publications 2001

  1. Andreyev HJN, Norman AR, Cunningham D, Oates J, Dix BR, Iacopetta BJ, Young J, Walsh T, Ward R, Hawkins N, Beranek M, Jandik P, Benamouzig R, Jullian E, Laurent-Puig P, Olschwang S, Muller O, Hoffmann I, Rabes HM, Zietz C, Troungos C, Valavanis C, Yuen ST, Ho JWC, Croke CT et al. (2001)
    Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study
    Br. J. Cancer, 85 (5), 692-696
    DOI 10.1054/bjoc.2001.1964
  2. Bjorheim J, Ekstrom PO, Fossberg E, Borresen-Dale AL, Gaudernack G (2001)
    Automated constant denaturant capillary electrophoresis applied for detection of KRAS exon 1 mutations
    Biotechniques, 30 (5), 972-975
  3. Bjorheim J, Gaudernack G, Ekstrom PO (2001)
    Mutation analysis of TP53 exons 5-8 by automated constant denaturant capillary electrophoresis
    Tumor Biol., 22 (5), 323-327
    DOI 10.1159/000050634
  4. Blystad AK, Holte H, Kvaloy S, Smeland E, Delabie J, Kvalheim G (2001)
    High-dose therapy in patients with Hodgkin's disease: the use of selected CD34(+) cells is as safe as unmanipulated peripheral blood progenitor cells
    Bone Marrow Transplant., 28 (9), 849-857
    DOI 10.1038/sj.bmt.1703244
  5. Gjertsen MK, Buanes T, Rosseland AR, Bakka A, Gladhaug I, Soreide O, Eriksen JA, Moller M, Baksaas I, Lothe RA, Saeterdal I, Gaudernack G (2001)
    Intradermal ras peptide vaccination with granulocyte-macrophage colony-stimulating factor as adjuvant: Clinical and immunological responses in patients with pancreatic adenocarcinoma
    Int. J. Cancer, 92 (3), 441-450
    DOI 10.1002/ijc.1205
  6. Hansen MH, Ostenstad B, Sioud M (2001)
    Antigen-specific IgG antibodies in stage IV long-time survival breast cancer patients
    Mol. Med., 7 (4), 230-239
    DOI 10.1007/BF03401842
  7. Hansen MH, Ostenstad B, Sioud M (2001)
    Identification of immunogenic antigens using a phage-displayed cDNA library from an invasive ductal breast carcinoma tumour
    Int. J. Oncol., 19 (6), 1303-1309
  8. Hunger RE, Brand CU, Streit M, Eriksen JA, Gjertsen MK, Saeterdal I, Braathen LR, Gaudernack G (2001)
    Successful induction of immune responses against mutant ras in melanoma patients using intradermal injection of peptides and GM-CSF as adjuvant
    Exp. Dermatol., 10 (3), 161-167
    DOI 10.1034/j.1600-0625.2001.010003161.x
  9. Iversen PO, Nicolaysen G, Sioud M (2001)
    DNA enzyme targeting TNF-alpha mRNA improves hemodynamic performance in rats with postinfarction heart failure
    Am. J. Physiol.-Heart Circul. Physiol., 281 (5), H2211-H2217
    DOI 10.1152/ajpheart.2001.281.5.H2211
  10. Melien O, Christoffersen T, Sioud M (2001)
    Evidence for the involvement of G(i2) in activation of extracellular signal-regulated kinases in hepatocytes
    BMC Cell Biol., 2, art. no.-13
    DOI 10.1186/1471-2121-2-13
  11. Rian E, Wabakken T, Hauge H, Aasheim HC (2001)
    A signal sequence trap based on cell enrichment using Anti-CD19 antibody coated magnetic beads
    Scand. J. Immunol., 54 (3), 280-284
    DOI 10.1046/j.1365-3083.2001.00925.x
  12. Saeterdal I, Bjorheim J, Lislerud K, Gjertsen MK, Bukholm IK, Olsen OC, Nesland JM, Eriksen JA, Moller M, Lindblom A, Gaudernack G (2001)
    Frameshift-mutation-derived peptides as tumor-specific antigens in inherited and spontaneous colorectal cancer
    Proc. Natl. Acad. Sci. U. S. A., 98 (23), 13255-13260
    DOI 10.1073/pnas.231326898
  13. Saeterdal I, Gjertsen MK, Straten P, Eriksen JA, Gaudernack G (2001)
    A TGF beta RII frameshift-mutation-derived CTL epitope recognised by HLA-A2-restricted CD8(+) T cells
    Cancer Immunol. Immunother., 50 (9), 469-476
    DOI 10.1007/s002620100222
  14. Shadidi M, Sioud M (2001)
    An anti-leukemic single chain Fv antibody selected from a synthetic human phage antibody library
    Biochem. Biophys. Res. Commun., 280 (2), 548-552
    DOI 10.1006/bbrc.2000.4158
  15. Sioud M, Hansen MH (2001)
    Profiling the immune response in patients with breast cancer by phage-displayed cDNA libraries
    Eur. J. Immunol., 31 (3), 716-725
    DOI 10.1002/1521-4141(200103)31:3<716::AID-IMMU716>3.0.CO;2-9

Publications 2000

  1. Fossa A, Siebert R, Aasheim HC, Maelandsmo GM, Berner A, Fossa SD, Paus E, Smeland EB, Gaudernack G (2000)
    Identification of nucleolar protein No55 as a tumour-associated autoantigen in patients with prostate cancer
    Br. J. Cancer, 83 (6), 743-749
    DOI 10.1054/bjoc.2000.1365
  2. Hansen MH, Dybwad A, Forre O, Sioud M (2000)
    Probing antinuclear antibody specificities by peptide phage display libraries
    Clin. Exp. Rheumatol., 18 (4), 465-472
  3. Josefsen D, Myklebust JH, Lomo J, Sioud M, Blomhoff HK, Smeland EB (2000)
    Differential expression of Bcl-2 homologs in human CD34(+) hematopoietic progenitor cells induced to differentiate into erythroid or granulocytic cells
    Stem Cells, 18 (4), 261-272
    DOI 10.1634/stemcells.18-4-261
  4. Munthe E, Rian E, Holien T, Rasmussen AM, Levy FO, Aasheim HC (2000)
    Ephrin-B2 is a candidate ligand for the Eph receptor, EphB6
    FEBS Lett., 466 (1), 169-174
    DOI 10.1016/S0014-5793(99)01793-7
  5. Myklebust JH, Smeland EB, Josefsen D, Sioud M (2000)
    Protein kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation of CD34(+) progenitor cells from human bone marrow
    Blood, 95 (2), 510-518
    DOI 10.1182/blood.V95.2.510
  6. Reppe S, Rian E, Jemtland R, Olstad OK, Gautvik VT, Gautvik KM (2000)
    Sox-4 messenger RNA is expressed in the embryonic growth plate and regulated via the parathyroid hormone/parathyroid hormone-related protein receptor in osteoblast-like cells
    J. Bone Miner. Res., 15 (12), 2402-2412
    DOI 10.1359/jbmr.2000.15.12.2402
  7. Rosok O, Pedeutour F, Odeberg J, Lundeberg J, Aasheim HC (2000)
    The C1orf9 gene encodes a putative transmembrane member of a novel protein family
    Biochem. Biophys. Res. Commun., 267 (3), 855-862
    DOI 10.1006/bbrc.1999.2016
  8. Sioud M, Hansen M, Dybwad A (2000)
    Profiling the immune responses in patient sera with peptide and cDNA display libraries (Review)
    Int. J. Mol. Med., 6 (2), 123-128
  9. Sioud M, Leirdal M (2000)
    Design of nuclease resistant protein kinase C alpha DNA enzymes with potential therapeutic application
    J. Mol. Biol., 296 (3), 937-947
    DOI 10.1006/jmbi.2000.3491
  10. Sioud M, Leirdal M (2000)
    Therapeutic RNA and DNA enzymes
    Biochem. Pharmacol., 60 (8), 1023-1026
    DOI 10.1016/S0006-2952(00)00395-6