Publications by Johannes Espolin Roksund Hov

143 publications found

Publications 2024

1. Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2024)
   Retraction Note: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
   Sci Rep, 14 (1), 3704
   DOI 10.1038/s41598-024-54117-6, PubMed 38355714
2. Lin W, Gerullat L, Braadland PR, Fournier A, Hov JR, Globisch D (2024)
   Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4-Nitrophenyl-2H-azirine
   Angew Chem Int Ed Engl, 63 (14), e202318579
   DOI 10.1002/anie.202318579, PubMed 38235602
3. Nikitina D, Lukosevicius R, Tilinde D, Muskieta T, Hov JR, Melum E, Klovins J, Org E, Kiudelis G, Kupcinskas J, Skieceviciene J (2024)
   Cell-Free Microbial DNA Analysis: Effects of Blood Plasma and Serum Quantity, Biobanking Protocols, and Isolation Kits
   Biopreserv Biobank (in press)
   DOI 10.1089/bio.2023.0048, PubMed 38416864
4. Raju SC, Molinaro A, Awoyemi A, Jørgensen SF, Braadland PR, Nendl A, Seljeflot I, Ueland PM, McCann A, Aukrust P, Vestad B, Mayerhofer C, Broch K, Gullestad L, Lappegård KT, Halvorsen B, Kristiansen K, Hov JR, Trøseid M (2024)
   Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity
   Genome Med, 16 (1), 27
   DOI 10.1186/s13073-024-01296-6, PubMed 38331891
5. Serrano-Villar S, Tincati C, Raju SC, Sáenz JS, Moreno E, Bargiela R, Cabello-Ubeda A, Sendagorta E, Kurz A, Perez Molina JA, de Benito A, Hov JR, Fernandez-Lopez L, Muriel A, Del Campo R, Moreno S, Trøseid M, Seifert J, Ferrer M (2024)
   Author Correction: Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer
   Nat Med, 30 (1), 303
   DOI 10.1038/s41591-023-02529-8, PubMed 37587221
6. Trøseid M, Molinaro A, Gelpi M, Vestad B, Kofoed KF, Fuchs A, Køber L, Holm K, Benfield T, Ueland PM, Hov JR, Nielsen SD, Knudsen AD (2024)
   Gut Microbiota Alterations and Circulating Imidazole Propionate Levels Are Associated With Obstructive Coronary Artery Disease in People With HIV
   J Infect Dis, 229 (3), 898-907
   DOI 10.1093/infdis/jiad604, PubMed 38195204

Publications 2023

1. Braadland PR, Bergquist A, Kummen M, Bossen L, Engesæter LK, Reims HM, Björk I, Grzyb K, Abildgaard A, Småstuen MC, Folseraas T, Trøseid M, Ulvik A, Ueland PM, Melum E, Line PD, Høivik ML, Grønbæk H, Karlsen TH, Vesterhus M, Hov JR (2023)
   Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation
   J Hepatol, 79 (4), 955-966
   DOI 10.1016/j.jhep.2023.05.038, PubMed 37328069
2. Gui W, Hole MJ, Molinaro A, Edlund K, Jørgensen KK, Su H, Begher-Tibbe B, Gaßler N, Schneider CV, Muthukumarasamy U, Mohs A, Liao L, Jaeger J, Mertens CJ, Bergheim I, Strowig T, Hengstler JG, Hov JR, Marschall HU, Trautwein C, Schneider KM (2023)
   Colitis ameliorates cholestatic liver disease via suppression of bile acid synthesis
   Nat Commun, 14 (1), 3304
   DOI 10.1038/s41467-023-38840-8, PubMed 37280200
3. Hole MJ, Jørgensen KK, Holm K, Braadland PR, Meyer-Myklestad MH, Medhus AW, Reikvam DH, Götz A, Grzyb K, Boberg KM, Karlsen TH, Kummen M, Hov JR (2023)
   A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation
   Hepatology, 77 (3), 715-728
   DOI 10.1002/hep.32773, PubMed 36056902
4. Hole MJ, Jørgensen KK, Holm K, Braadland PR, Meyer-Myklestad MH, Medhus AW, Reikvam DH, Götz A, Grzyb K, Boberg KM, Karlsen TH, Kummen M, Hov JR (2023)
   Reply: The mucosal gut signature in primary sclerosing cholangitis before and after liver transplantation. Is the dysbiosis index really predictive for the recurrence of PSC?
   Hepatology, 77 (6), E188-E189
   DOI 10.1097/HEP.0000000000000340, PubMed 36815351
5. Hov JR (2023)
   Editorial: dietary interventions to understand and treat primary sclerosing cholangitis-is gluten-free diet a starting point?
   Aliment Pharmacol Ther, 57 (2), 265-266
   DOI 10.1111/apt.17326, PubMed 36565005
6. Juul FE, Hov JER, Trøseid M, Johnsen PH, Valeur J (2023)
   [Not Available]
   Tidsskr Nor Laegeforen, 143 (10)
   DOI 10.4045/tidsskr.23.0121, PubMed 37376933
7. Macpherson ME, Skarpengland T, Hov JR, Ranheim T, Vestad B, Dahl TB, Fraz MSA, Michelsen AE, Holven KB, Fevang B, Berge RK, Aukrust P, Halvorsen B, Jørgensen SF (2023)
   Increased Plasma Levels of Triglyceride-Enriched Lipoproteins Associate with Systemic Inflammation, Lipopolysaccharides, and Gut Dysbiosis in Common Variable Immunodeficiency
   J Clin Immunol, 43 (6), 1229-1240
   DOI 10.1007/s10875-023-01475-x, PubMed 36995502
8. Mikaeloff F, Gelpi M, Benfeitas R, Knudsen AD, Vestad B, Høgh J, Hov JR, Benfield T, Murray D, Giske CG, Mardinoglu A, Trøseid M, Nielsen SD, Neogi U (2023)
   Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection
   Elife, 12
   DOI 10.7554/eLife.82785, PubMed 36794912
9. Nendl A, Raju SC, Broch K, Mayerhofer CCK, Holm K, Halvorsen B, Lappegård KT, Moscavitch S, Hov JR, Seljeflot I, Trøseid M, Awoyemi A (2023)
   Intestinal fatty acid binding protein is associated with cardiac function and gut dysbiosis in chronic heart failure
   Front Cardiovasc Med, 10, 1160030
   DOI 10.3389/fcvm.2023.1160030, PubMed 37332580
10. Schneider KM, Kummen M, Trivedi PJ, Hov JR (2023)
    Role of microbiome in autoimmune liver diseases
    Hepatology (in press)
    DOI 10.1097/HEP.0000000000000506, PubMed 37369002
11. Serrano-Villar S, Tincati C, Raju SC, Sáenz JS, Moreno E, Bargiela R, Cabello-Ubeda A, Sendagorta E, Kurz A, Perez Molina JA, de Benito A, Hov JR, Fernandez-Lopez L, Muriel A, Del Campo R, Moreno S, Trøseid M, Seifert J, Ferrer M (2023)
    Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer
    Nat Med, 29 (7), 1738-1749
    DOI 10.1038/s41591-023-02407-3, PubMed 37464040
12. Trøseid M, Holter JC, Holm K, Vestad B, Sazonova T, Granerud BK, Dyrhol-Riise AM, Holten AR, Tonby K, Kildal AB, Heggelund L, Tveita A, Bøe S, Müller KE, Jenum S, Hov JR, Ueland T, Norwegian SARS-CoV-2 study group (2023)
    Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19
    Crit Care, 27 (1), 69
    DOI 10.1186/s13054-023-04356-2, PubMed 36814280

Publications 2022

1. Awoniyi M, Wang J, Ngo B, Meadows V, Tam J, Viswanathan A, Lai Y, Montgomery S, Farmer M, Kummen M, Thingholm L, Schramm C, Bang C, Franke A, Lu K, Zhou H, Bajaj JS, Hylemon PB, Ting J, Popov YV, Hov JR, Francis HL, Sartor RB (2022)
   Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC
   Gut, 72 (4), 671-685
   DOI 10.1136/gutjnl-2021-326500, PubMed 35705368
2. Awoyemi A, Hov JR, Trøseid M (2022)
   Phenylacetylglutamine From the Gut Microbiota: A Future Therapeutic Target in Heart Failure?
   Circ Heart Fail, 16 (1), e010222
   DOI 10.1161/CIRCHEARTFAILURE.122.010222, PubMed 36524473
3. Braadland PR, Schneider KM, Bergquist A, Molinaro A, Lövgren-Sandblom A, Henricsson M, Karlsen TH, Vesterhus M, Trautwein C, Hov JR, Marschall HU (2022)
   Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis
   JHEP Rep, 4 (11), 100561
   DOI 10.1016/j.jhepr.2022.100561, PubMed 36176935
4. Cruz R, Diz-de Almeida S, López de Heredia M, Quintela I, Ceballos FC, Pita G, Lorenzo-Salazar JM, González-Montelongo R, Gago-Domínguez M, Sevilla Porras M, Tenorio Castaño JA, Nevado J, Aguado JM, Aguilar C, Aguilera-Albesa S, Almadana V, Almoguera B, Alvarez N, Andreu-Bernabeu Á, Arana-Arri E, Arango C, Arranz MJ, Artiga MJ, Baptista-Rosas RC, Barreda-Sánchez M et al. (2022)
   Novel genes and sex differences in COVID-19 severity
   Hum Mol Genet, 31 (22), 3789-3806
   DOI 10.1093/hmg/ddac132, PubMed 35708486
5. Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H, Rühlemann MC, Arora J, Özer O, Lenning OB, Myhre R, Vadla MS, Wacker EM, Wienbrandt L, Blandino Ortiz A, de Salazar A, Garrido Chercoles A, Palom A, Ruiz A, Garcia-Fernandez AE, Blanco-Grau A, Mantovani A, Zanella A et al. (2022)
   Detailed stratified GWAS analysis for severe COVID-19 in four European populations
   Hum Mol Genet, 31 (23), 3945-3966
   DOI 10.1093/hmg/ddac158, PubMed 35848942
6. Gelpi M, Vestad B, Raju SC, Hansen SH, Høgh J, Midttun Ø, Ueland PM, Ueland T, Benfield T, Kofoed KF, Hov JR, Trøseid M, Nielsen SD (2022)
   Association of the Kynurenine Pathway of Tryptophan Metabolism With Human Immunodeficiency Virus-Related Gut Microbiota Alterations and Visceral Adipose Tissue Accumulation
   J Infect Dis, 225 (11), 1948-1954
   DOI 10.1093/infdis/jiac018, PubMed 35089326
7. Hov JR, Karlsen TH (2022)
   The microbiota and the gut-liver axis in primary sclerosing cholangitis
   Nat Rev Gastroenterol Hepatol, 20 (3), 135-154
   DOI 10.1038/s41575-022-00690-y, PubMed 36352157
8. Kaarbø M, Yang M, Hov JR, Holm K, de Sousa MML, Macpherson ME, Reims HM, Kran AB, Halvorsen B, Karlsen TH, Aukrust P, Lundin KEA, Fevang B, Bjørås M, Jørgensen SF (2022)
   Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses
   J Allergy Clin Immunol, 151 (3), 767-777
   DOI 10.1016/j.jaci.2022.09.029, PubMed 36220400
9. Meyer-Myklestad MH, Medhus AW, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Stiksrud B, Trøseid M, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Reikvam DH (2022)
   Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction
   J Infect Dis, 225 (4), 661-674
   DOI 10.1093/infdis/jiaa714, PubMed 33216130
10. Meyer-Myklestad MH, Medhus AW, Stiksrud B, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Trøseid M, Reikvam DH (2022)
    Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
    J Acquir Immune Defic Syndr, 89 (1), 77-86
    DOI 10.1097/QAI.0000000000002817, PubMed 34878437
11. Storm-Larsen C, Hande LN, Kummen M, Thunhaug H, Vestad B, Hansen SH, Hovland A, Trøseid M, Lappegård KT, Hov JR (2022)
    Reduced gut microbial diversity in familial hypercholesterolemia with no effect of omega-3 polyunsaturated fatty acids intervention - a pilot trial
    Scand J Clin Lab Invest, 82 (5), 363-370
    DOI 10.1080/00365513.2022.2102540, PubMed 35913798
12. Stø K, Valeur J, Ueland T, Malmstrøm GH, Bjerkeli V, Trøseid M, Hov JR, Holm K, Vestad B, Halvorsen B, Skjelland M, Skagen KR (2022)
    Fecal level of butyric acid, a microbiome-derived metabolite, is increased in patients with severe carotid atherosclerosis
    Sci Rep, 12 (1), 22378
    DOI 10.1038/s41598-022-26759-x, PubMed 36572703
13. Valestrand L, Zheng F, Hansen SH, Øgaard J, Hov JR, Björkström NK, Karlsen TH, Jiang X, Melum E (2022)
    Bile from Patients with Primary Sclerosing Cholangitis Contains Mucosal-Associated Invariant T-Cell Antigens
    Am J Pathol, 192 (4), 629-641
    DOI 10.1016/j.ajpath.2021.12.008, PubMed 35063408
14. Vestad B, Ueland T, Lerum TV, Dahl TB, Holm K, Barratt-Due A, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Tonby K, Hoel H, Olsen IC, Henriksen KN, Tveita A, Manotheepan R, Haugli M, Eiken R, Berg Å, Halvorsen B, Lekva T, Ranheim T, Michelsen AE, Kildal AB, Johannessen A, Thoresen L et al. (2022)
    Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
    J Intern Med, 291 (6), 801-812
    DOI 10.1111/joim.13458, PubMed 35212063

Publications 2021

1. Awoyemi A, Mayerhofer C, Felix AS, Hov JR, Moscavitch SD, Lappegård KT, Hovland A, Halvorsen S, Halvorsen B, Gregersen I, Svardal A, Berge RK, Hansen SH, Götz A, Holm K, Aukrust P, Åkra S, Seljeflot I, Solheim S, Lorenzo A, Gullestad L, Trøseid M, Broch K (2021)
   Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
   EBioMedicine, 70, 103511
   DOI 10.1016/j.ebiom.2021.103511, PubMed 34329947
2. Bossen L, Vesterhus M, Hov JR, Färkkilä M, Rosenberg WM, Møller HJ, Boberg KM, Karlsen TH, Grønbæk H (2021)
   Circulating Macrophage Activation Markers Predict Transplant-Free Survival in Patients With Primary Sclerosing Cholangitis
   Clin Transl Gastroenterol, 12 (3), e00315
   DOI 10.14309/ctg.0000000000000315, PubMed 33646203
3. Dhillon AK, Rupp C, Bergquist A, Voitl R, Folseraas T, Trøseid M, Midttun Ø, Ueland PM, Karlsen TH, Vesterhus M, Kummen M, Hov JR (2021)
   Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis
   Scand J Gastroenterol, 56 (4), 443-452
   DOI 10.1080/00365521.2021.1880627, PubMed 33583308
4. Karlsen TR, Kong XY, Holm S, Quiles-Jiménez A, Dahl TB, Yang K, Sagen EL, Skarpengland T, S Øgaard JD, Holm K, Vestad B, Olsen MB, Aukrust P, Bjørås M, Hov JR, Halvorsen B, Gregersen I (2021)
   NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype
   Sci Rep, 11 (1), 19749
   DOI 10.1038/s41598-021-98820-0, PubMed 34611194
5. Nakanishi T, Pigazzini S, Degenhardt F, Cordioli M, Butler-Laporte G, Maya-Miles D, Bujanda L, Bouysran Y, Niemi ME, Palom A, Ellinghaus D, Khan A, Martínez-Bueno M, Rolker S, Amitrano S, Roade Tato L, Fava F, FinnGen, COVID-19 Host Genetics Initiative (HGI), Spinner CD, Prati D, Bernardo D, Garcia F, Darcis G, Fernández-Cadenas I et al. (2021)
   Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality
   J Clin Invest, 131 (23)
   DOI 10.1172/JCI152386, PubMed 34597274
6. Nakanishi T, Pigazzini S, Degenhardt F, Cordioli M, Butler-Laporte G, Maya-Miles D, Nafría-Jiménez B, Bouysran Y, Niemi M, Palom A, Ellinghaus D, Khan A, Martínez-Bueno M, Rolker S, Amitano S, Tato LR, FinnGen, The COVID-19 Host Genetics Initiative, Fava F, Spinner CD, Prati D, Bernardo D, Garcia F, Darcis G, Fernández-Cadenas I, Holter JC et al. (2021)
   Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality
   medRxiv
   DOI 10.1101/2021.03.07.21252875, PubMed 33758887
7. Reich M, Spomer L, Klindt C, Fuchs K, Stindt J, Deutschmann K, Höhne J, Liaskou E, Hov JR, Karlsen TH, Beuers U, Verheij J, Ferreira-Gonzalez S, Hirschfield G, Forbes SJ, Schramm C, Esposito I, Nierhoff D, Fickert P, Fuchs CD, Trauner M, García-Beccaria M, Gabernet G, Nahnsen S, Mallm JP et al. (2021)
   Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis
   J Hepatol, 75 (3), 634-646
   DOI 10.1016/j.jhep.2021.03.029, PubMed 33872692
8. Schneider KM, Candels LS, Hov JR, Myllys M, Hassan R, Schneider CV, Wahlström A, Mohs A, Zühlke S, Liao L, Elfers C, Kilic K, Henricsson M, Molinaro A, Hatting M, Zaza A, Drasdo D, Frissen M, Devlin AS, Gálvez EJC, Strowig T, Karlsen TH, Hengstler JG, Marschall HU, Ghallab A et al. (2021)
   Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling
   Nat Metab, 3 (9), 1228-1241
   DOI 10.1038/s42255-021-00452-1, PubMed 34552267
9. Skarpengland T, Macpherson ME, Hov JR, Kong XY, Bohov P, Halvorsen B, Fevang B, Berge RK, Aukrust P, Jørgensen SF (2021)
   Altered Plasma Fatty Acids Associate with Gut Microbial Composition in Common Variable Immunodeficiency
   J Clin Immunol, 42 (1), 146-157
   DOI 10.1007/s10875-021-01146-9, PubMed 34669143
10. Skaarud KJ, Hov JR, Hansen SH, Kummen M, Valeur J, Seljeflot I, Bye A, Paulsen V, Lundin KEA, Trøseid M, Tjønnfjord GE, Iversen PO (2021)
    Mortality and microbial diversity after allogeneic hematopoietic stem cell transplantation: secondary analysis of a randomized nutritional intervention trial
    Sci Rep, 11 (1), 11593
    DOI 10.1038/s41598-021-90976-z, PubMed 34078971
11. Vestad B, Nyman TA, Hove-Skovsgaard M, Stensland M, Hoel H, Trøseid AS, Aspelin T, Aass HCD, Puhka M, Hov JR, Nielsen SD, Øvstebø R, Trøseid M (2021)
    Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk
    Sci Rep, 11 (1), 21936
    DOI 10.1038/s41598-021-01334-y, PubMed 34754007
12. Zimmer CL, von Seth E, Buggert M, Strauss O, Hertwig L, Nguyen S, Wong AYW, Zotter C, Berglin L, Michaëlsson J, Hansson MR, Arnelo U, Sparrelid E, Ellis ECS, Söderholm JD, Keita ÅV, Holm K, Özenci V, Hov JR, Mold JE, Cornillet M, Ponzetta A, Bergquist A, Björkström NK (2021)
    A biliary immune landscape map of primary sclerosing cholangitis reveals a dominant network of neutrophils and tissue-resident T cells
    Sci Transl Med, 13 (599)
    DOI 10.1126/scitranslmed.abb3107, PubMed 34162753

Publications 2020

1. Derer S, Brethack AK, Pietsch C, Jendrek ST, Nitzsche T, Bokemeyer A, Hov JR, Schäffler H, Bettenworth D, Grassl GA, Sina C (2020)
   Inflammatory Bowel Disease-associated GP2 Autoantibodies Inhibit Mucosal Immune Response to Adherent-invasive Bacteria
   Inflamm Bowel Dis, 26 (12), 1856-1868
   DOI 10.1093/ibd/izaa069, PubMed 32304568
2. Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
   Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
   PLoS One, 15 (5), e0232739
   DOI 10.1371/journal.pone.0232739, PubMed 32437393
3. Gelpi M, Vestad B, Hansen SH, Holm K, Drivsholm N, Goetz A, Kirkby NS, Lindegaard B, Lebech AM, Hoel H, Michelsen AE, Ueland T, Gerstoft J, Lundgren J, Hov JR, Nielsen SD, Trøseid M (2020)
   Impact of Human Immunodeficiency Virus-Related Gut Microbiota Alterations on Metabolic Comorbid Conditions
   Clin Infect Dis, 71 (8), e359-e367
   DOI 10.1093/cid/ciz1235, PubMed 31894240
4. Kummen M, Solberg OG, Storm-Larsen C, Holm K, Ragnarsson A, Trøseid M, Vestad B, Skårdal R, Yndestad A, Ueland T, Svardal A, Berge RK, Seljeflot I, Gullestad L, Karlsen TH, Aaberge L, Aukrust P, Hov JR (2020)
   Rosuvastatin alters the genetic composition of the human gut microbiome
   Sci Rep, 10 (1), 5397
   DOI 10.1038/s41598-020-62261-y, PubMed 32214138
5. Kummen M, Thingholm LB, Rühlemann MC, Holm K, Hansen SH, Moitinho-Silva L, Liwinski T, Zenouzi R, Storm-Larsen C, Midttun Ø, McCann A, Ueland PM, Høivik ML, Vesterhus M, Trøseid M, Laudes M, Lieb W, Karlsen TH, Bang C, Schramm C, Franke A, Hov JR (2020)
   Altered Gut Microbial Metabolism of Essential Nutrients in Primary Sclerosing Cholangitis
   Gastroenterology, 160 (5), 1784-1798.e0
   DOI 10.1053/j.gastro.2020.12.058, PubMed 33387530
6. Macpherson ME, Hov JR, Ueland T, Dahl TB, Kummen M, Otterdal K, Holm K, Berge RK, Mollnes TE, Trøseid M, Halvorsen B, Aukrust P, Fevang B, Jørgensen SF (2020)
   Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
   Front Immunol, 11, 574500
   DOI 10.3389/fimmu.2020.574500, PubMed 33042155
7. Mayerhofer CCK, Kummen M, Holm K, Broch K, Awoyemi A, Vestad B, Storm-Larsen C, Seljeflot I, Ueland T, Bohov P, Berge RK, Svardal A, Gullestad L, Yndestad A, Aukrust P, Hov JR, Trøseid M (2020)
   Low fibre intake is associated with gut microbiota alterations in chronic heart failure
   ESC Heart Fail, 7 (2), 456-466
   DOI 10.1002/ehf2.12596, PubMed 31978943
8. Severe Covid-19 GWAS Group, Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, Fernández J, Prati D, Baselli G, Asselta R, Grimsrud MM, Milani C, Aziz F, Kässens J, May S, Wendorff M, Wienbrandt L, Uellendahl-Werth F, Zheng T, Yi X, de Pablo R, Chercoles AG, Palom A, Garcia-Fernandez AE et al. (2020)
   Genomewide Association Study of Severe Covid-19 with Respiratory Failure
   N Engl J Med, 383 (16), 1522-1534
   DOI 10.1056/NEJMoa2020283, PubMed 32558485
9. Sokolova M, Yang K, Hansen SH, Louwe MC, Kummen M, Hov JER, Sjaastad I, Berge RK, Halvorsen B, Aukrust P, Yndestad A, Ranheim T (2020)
   NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet
   Sci Rep, 10 (1), 21006
   DOI 10.1038/s41598-020-76497-1, PubMed 33273482
10. Trøseid M, Andersen GØ, Broch K, Hov JR (2020)
    The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions
    EBioMedicine, 52, 102649
    DOI 10.1016/j.ebiom.2020.102649, PubMed 32062353
11. Valestrand L, Berntsen NL, Zheng F, Schrumpf E, Hansen SH, Karlsen TH, Blumberg RS, Hov JR, Jiang X, Melum E (2020)
    Lipid antigens in bile from patients with chronic liver diseases activate natural killer T cells
    Clin Exp Immunol, 203 (2), 304-314
    DOI 10.1111/cei.13541, PubMed 33089489
12. Vesterhus M, Nielsen MJ, Hov JR, Saffioti F, Manon-Jensen T, Leeming DJ, Moum B, Boberg KM, Pinzani M, Karlsen TH, Karsdal MA, Thorburn D (2020)
    Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease
    JHEP Rep, 3 (1), 100178
    DOI 10.1016/j.jhepr.2020.100178, PubMed 33225252

Publications 2019

1. Dhillon AK, Kremer AE, Kummen M, Boberg KM, Elferink RPO, Karlsen TH, Beuers U, Vesterhus M, Hov JR (2019)
   Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis
   Sci Rep, 9 (1), 8450
   DOI 10.1038/s41598-019-44762-7, PubMed 31186435
2. Hov JR (2019)
   Editorial: proton pump inhibition - microbial complications beyond dysbiosis
   Aliment Pharmacol Ther, 50 (8), 962-963
   DOI 10.1111/apt.15495, PubMed 31591776
3. Jørgensen SF, Holm K, Macpherson ME, Storm-Larsen C, Kummen M, Fevang B, Aukrust P, Hov JR (2019)
   Selective IgA deficiency in humans is associated with reduced gut microbial diversity
   J Allergy Clin Immunol, 143 (5), 1969-1971.e11
   DOI 10.1016/j.jaci.2019.01.019, PubMed 30707969
4. Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2019)
   Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
   Sci Rep, 9 (1), 167 (Retracted)
   DOI 10.1038/s41598-018-35367-7, PubMed 30655568
5. Kummen M, Hov JR (2019)
   The gut microbial influence on cholestatic liver disease
   Liver Int, 39 (7), 1186-1196
   DOI 10.1111/liv.14153, PubMed 31125502
6. Liwinski T, Zenouzi R, John C, Ehlken H, Rühlemann MC, Bang C, Groth S, Lieb W, Kantowski M, Andersen N, Schachschal G, Karlsen TH, Hov JR, Rösch T, Lohse AW, Heeren J, Franke A, Schramm C (2019)
   Alterations of the bile microbiome in primary sclerosing cholangitis
   Gut, 69 (4), 665-672
   DOI 10.1136/gutjnl-2019-318416, PubMed 31243055
7. Lunder AK, Bakstad LT, Jahnsen J, Borthne A, Hov JR, Vatn M, Negård A (2019)
   Assessment of Bowel Inflammation and Strictures by Magnetic Resonance Enterography in Long-term Crohn's Disease
   J Crohns Colitis, 13 (5), 607-614
   DOI 10.1093/ecco-jcc/jjy208, PubMed 30541145
8. Mayerhofer CCK, Awoyemi A, Hov JR, Trøseid M, Broch K (2019)
   Reply: Potential risk associated with direct modulation of the gut flora in patients with heart failure
   ESC Heart Fail, 6 (3), 557-558
   DOI 10.1002/ehf2.12437, PubMed 31034162
9. Mazzawi T, Hausken T, Hov JR, Valeur J, Sangnes DA, El-Salhy M, Gilja OH, Hatlebakk JG, Lied GA (2019)
   Clinical response to fecal microbiota transplantation in patients with diarrhea-predominant irritable bowel syndrome is associated with normalization of fecal microbiota composition and short-chain fatty acid levels
   Scand J Gastroenterol, 54 (6), 690-699
   DOI 10.1080/00365521.2019.1624815, PubMed 31190584
10. Rühlemann MC, Solovjeva MEL, Zenouzi R, Liwinski T, Kummen M, Lieb W, Hov JR, Schramm C, Franke A, Bang C (2019)
    Gut mycobiome of primary sclerosing cholangitis patients is characterised by an increase of Trichocladium griseum and Candida species
    Gut, 69 (10), 1890-1892
    DOI 10.1136/gutjnl-2019-320008, PubMed 31653787
11. Saffioti F, Roccarina D, Vesterhus M, Hov JR, Rosenberg W, Pinzani M, Pereira SP, Boberg KM, Thorburn D (2019)
    Cholangiocarcinoma is associated with a raised enhanced liver fibrosis score independent of primary sclerosing cholangitis
    Eur J Clin Invest, 49 (5), e13088
    DOI 10.1111/eci.13088, PubMed 30762236
12. Storm-Larsen C, Myhr KM, Farbu E, Midgard R, Nyquist K, Broch L, Berg-Hansen P, Buness A, Holm K, Ueland T, Fallang LE, Burum-Auensen E, Hov JR, Holmøy T (2019)
    Gut microbiota composition during a 12-week intervention with delayed-release dimethyl fumarate in multiple sclerosis - a pilot trial
    Mult Scler J Exp Transl Clin, 5 (4), 2055217319888767
    DOI 10.1177/2055217319888767, PubMed 31798939
13. Storm-Larsen C, Stiksrud B, Eriksen C, Nowak P, Holm K, Thalme A, Dyrhol-Riise AM, Brix S, Hov JR, Trøseid M (2019)
    Microbial translocation revisited: targeting the endotoxic potential of gut microbes in HIV-infected individuals
    AIDS, 33 (4), 645-653
    DOI 10.1097/QAD.0000000000002087, PubMed 30531315
14. Trøseid M, Mayerhofer CCK, Broch K, Arora S, Svardal A, Hov JR, Andreassen AK, Gude E, Karason K, Dellgren G, Berge RK, Gullestad L, Aukrust P, Ueland T (2019)
    The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
    J Heart Lung Transplant, 38 (10), 1097-1103
    DOI 10.1016/j.healun.2019.06.003, PubMed 31301965

Publications 2018

1. Arnbjerg CJ, Vestad B, Hov JR, Pedersen KK, Jespersen S, Johannesen HH, Holm K, Halvorsen B, Fallentin E, Hansen AE, Lange T, Kjær A, Trøseid M, Fischer BM, Nielsen SD (2018)
   Effect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals
   J Acquir Immune Defic Syndr, 78 (4), 450-457
   DOI 10.1097/QAI.0000000000001693, PubMed 29874201
2. Dhillon AK, Kummen M, Trøseid M, Åkra S, Liaskou E, Moum B, Vesterhus M, Karlsen TH, Seljeflot I, Hov JR (2018)
   Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis
   Liver Int, 39 (2), 371-381
   DOI 10.1111/liv.13979, PubMed 30269440
3. Hoel H, Hove-Skovsgaard M, Hov JR, Gaardbo JC, Holm K, Kummen M, Rudi K, Nwosu F, Valeur J, Gelpi M, Seljeflot I, Ueland PM, Gerstoft J, Ullum H, Aukrust P, Nielsen SD, Trøseid M (2018)
   Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
   Sci Rep, 8 (1), 6725
   DOI 10.1038/s41598-018-25168-3, PubMed 29712976
4. Kummen M, Mayerhofer CCK, Vestad B, Broch K, Awoyemi A, Storm-Larsen C, Ueland T, Yndestad A, Hov JR, Trøseid M (2018)
   Gut Microbiota Signature in Heart Failure Defined From Profiling of 2 Independent Cohorts
   J Am Coll Cardiol, 71 (10), 1184-1186
   DOI 10.1016/j.jacc.2017.12.057, PubMed 29519360
5. Mayerhofer CCK, Awoyemi AO, Moscavitch SD, Lappegård KT, Hov JR, Aukrust P, Hovland A, Lorenzo A, Halvorsen S, Seljeflot I, Gullestad L, Trøseid M, Broch K (2018)
   Design of the GutHeart-targeting gut microbiota to treat heart failure-trial: a Phase II, randomized clinical trial
   ESC Heart Fail, 5 (5), 977-984
   DOI 10.1002/ehf2.12332, PubMed 30088346
6. Mazzawi T, Lied GA, Sangnes DA, El-Salhy M, Hov JR, Gilja OH, Hatlebakk JG, Hausken T (2018)
   The kinetics of gut microbial community composition in patients with irritable bowel syndrome following fecal microbiota transplantation
   PLoS One, 13 (11), e0194904
   DOI 10.1371/journal.pone.0194904, PubMed 30427836
7. Nielsen MJ, Thorburn D, Leeming DJ, Hov JR, Nygård S, Moum B, Saffioti F, Gilja OH, Boberg KM, Mazza G, Røsjø H, Pinzani M, Karlsen TH, Karsdal MA, Vesterhus M (2018)
   Serological markers of extracellular matrix remodeling predict transplant-free survival in primary sclerosing cholangitis
   Aliment Pharmacol Ther, 48 (2), 179-189
   DOI 10.1111/apt.14806, PubMed 29851098
8. Pollheimer MJ, Racedo S, Mikels-Vigdal A, Marshall D, Bowlus C, Lackner C, Madl T, Karlsen TH, Hov JR, Lyman SK, Adamkewicz J, Smith V, Moreau E, Zollner G, Eide TJ, Stojakovic T, Scharnagl H, Gruber HJ, Stauber RE, Trauner M, Fickert P (2018)
   Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis
   J Hepatol, 69 (2), 368-377
   DOI 10.1016/j.jhep.2018.04.009, PubMed 29709678
9. Schmitt C, Lenglet H, Yu A, Delaby C, Benecke A, Lefebvre T, Letteron P, Paradis V, Wahlin S, Sandberg S, Harper P, Sardh E, Sandvik AK, Hov JR, Aarsand AK, Chiche L, Bazille C, Scoazec JY, To-Figueras J, Carrascal M, Abian J, Mirmiran A, Karim Z, Deybach JC, Puy H et al. (2018)
   Recurrent attacks of acute hepatic porphyria: major role of the chronic inflammatory response in the liver
   J Intern Med, 284 (1), 78-91
   DOI 10.1111/joim.12750, PubMed 29498764

Publications 2017

1. Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, Böttcher K, Folseraas T, Weismüller TJ, Mason AL, Wang W, Alexander G, Alvaro D, Bergquist A, Björkström NK, Beuers U, Björnsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouillères O, Cheung A, Dalekos G, Eaton J et al. (2017)
   Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis
   Gut, 67 (8), 1517-1524
   DOI 10.1136/gutjnl-2016-313598, PubMed 28779025
2. de Muinck EJ, Trosvik P, Gilfillan GD, Hov JR, Sundaram AYM (2017)
   A novel ultra high-throughput 16S rRNA gene amplicon sequencing library preparation method for the Illumina HiSeq platform
   Microbiome, 5 (1), 68
   DOI 10.1186/s40168-017-0279-1, PubMed 28683838
3. de Vries EMG, Färkkilä M, Milkiewicz P, Hov JR, Eksteen B, Thorburn D, Chazouillères O, Pares A, Nygård S, Gilja OH, Wunsch E, Invernizzi P, Carbone M, Bernuzzi F, Boberg KM, Røsjø H, Rosenberg W, Beuers UH, Ponsioen CY, Karlsen TH, Vesterhus M (2017)
   Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study
   Liver Int, 37 (10), 1554-1561
   DOI 10.1111/liv.13402, PubMed 28267887
4. Haissman JM, Haugaard AK, Ostrowski SR, Berge RK, Hov JR, Trøseid M, Nielsen SD (2017)
   Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection
   BMC Infect Dis, 17 (1), 445
   DOI 10.1186/s12879-017-2547-x, PubMed 28645263
5. Henriksen EKK, Viken MK, Wittig M, Holm K, Folseraas T, Mucha S, Melum E, Hov JR, Lazaridis KN, Juran BD, Chazouillères O, Färkkilä M, Gotthardt DN, Invernizzi P, Carbone M, Hirschfield GM, Rushbrook SM, Goode E, UK-PSC Consortium, Ponsioen CY, Weersma RK, Eksteen B, Yimam KK, Gordon SC, Goldberg D et al. (2017)
   HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry
   HLA, 90 (4), 228-233
   DOI 10.1111/tan.13076, PubMed 28695657
6. Hov JR, Karlsen TH (2017)
   The Microbiome in Primary Sclerosing Cholangitis: Current Evidence and Potential Concepts
   Semin Liver Dis, 37 (4), 314-331
   DOI 10.1055/s-0037-1608801, PubMed 29272894
7. Hov JR, Kummen M (2017)
   Intestinal microbiota in primary sclerosing cholangitis
   Curr Opin Gastroenterol, 33 (2), 85-92
   DOI 10.1097/MOG.0000000000000334, PubMed 28030369
8. Jahnsen FL, Bækkevold ES, Hov JR, Landsverk OJ (2017)
   Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?
   Trends Immunol, 39 (3), 196-208
   DOI 10.1016/j.it.2017.10.006, PubMed 29162322
9. Koch M, Freitag-Wolf S, Schlesinger S, Borggrefe J, Hov JR, Jensen MK, Pick J, Markus MRP, Höpfner T, Jacobs G, Siegert S, Artati A, Kastenmüller G, Römisch-Margl W, Adamski J, Illig T, Nothnagel M, Karlsen TH, Schreiber S, Franke A, Krawczak M, Nöthlings U, Lieb W (2017)
   Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample
   Eur J Clin Nutr, 71 (8), 995-1001
   DOI 10.1038/ejcn.2017.43, PubMed 28378853
10. Lunder AK, Jahnsen J, Bakstad LT, Borthne A, Hov JR, Vatn M, Negård A, IBSEN Study Group (2017)
    Bowel Damage in Patients With Long-term Crohn's Disease, Assessed by Magnetic Resonance Enterography and the Lémann Index
    Clin Gastroenterol Hepatol, 16 (1), 75-82.e5
    DOI 10.1016/j.cgh.2017.06.053, PubMed 28694130
11. Mayerhofer CCK, Ueland T, Broch K, Vincent RP, Cross GF, Dahl CP, Aukrust P, Gullestad L, Hov JR, Trøseid M (2017)
    Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure
    J Card Fail, 23 (9), 666-671
    DOI 10.1016/j.cardfail.2017.06.007, PubMed 28688889
12. Rühlemann MC, Degenhardt F, Thingholm LB, Wang J, Skiecevičienė J, Rausch P, Hov JR, Lieb W, Karlsen TH, Laudes M, Baines JF, Heinsen FA, Franke A (2017)
    Application of the distance-based F test in an mGWAS investigating β diversity of intestinal microbiota identifies variants in SLC9A8 (NHE8) and 3 other loci
    Gut Microbes, 9 (1), 68-75
    DOI 10.1080/19490976.2017.1356979, PubMed 28816579
13. Tronstad RR, Kummen M, Holm K, von Volkmann HL, Anmarkrud JA, Høivik ML, Moum B, Gilja OH, Hausken T, Baines J, Karlsen TH, Fiskerstrand T, Hov JR (2017)
    Guanylate Cyclase C Activation Shapes the Intestinal Microbiota in Patients with Familial Diarrhea and Increased Susceptibility for Crohn's Disease
    Inflamm Bowel Dis, 23 (10), 1752-1761
    DOI 10.1097/MIB.0000000000001264, PubMed 28902124
14. Vesterhus M, Holm A, Hov JR, Nygård S, Schrumpf E, Melum E, Thorbjørnsen LW, Paulsen V, Lundin K, Dale I, Gilja OH, Zweers SJLB, Vatn M, Schaap FG, Jansen PLM, Ueland T, Røsjø H, Moum B, Ponsioen CY, Boberg KM, Färkkilä M, Karlsen TH, Lund-Johansen F (2017)
    Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
    J Hepatol, 66 (6), 1214-1222
    DOI 10.1016/j.jhep.2017.01.019, PubMed 28161472
15. Volkmann ER, Hoffmann-Vold AM, Chang YL, Jacobs JP, Tillisch K, Mayer EA, Clements PJ, Hov JR, Kummen M, Midtvedt Ø, Lagishetty V, Chang L, Labus JS, Molberg Ø, Braun J (2017)
    Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts
    BMJ Open Gastroenterol, 4 (1), e000134
    DOI 10.1136/bmjgast-2017-000134, PubMed 28761687

Publications 2016

1. Hov JR, Boberg KM, Taraldsrud E, Vesterhus M, Boyadzhieva M, Solberg IC, Schrumpf E, Vatn MH, Lie BA, Molberg Ø, Karlsen TH (2016)
   Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis
   Liver Int, 37 (3), 458-465
   DOI 10.1111/liv.13238, PubMed 27558072
2. Jendrek ST, Gotthardt D, Nitzsche T, Widmann L, Korf T, Michaels MA, Weiss KH, Liaskou E, Vesterhus M, Karlsen TH, Mindorf S, Schemmer P, Bär F, Teegen B, Schröder T, Ehlers M, Hammers CM, Komorowski L, Lehnert H, Fellermann K, Derer S, Hov JR, Sina C (2016)
   Anti-GP2 IgA autoantibodies are associated with poor survival and cholangiocarcinoma in primary sclerosing cholangitis
   Gut, 66 (1), 137-144
   DOI 10.1136/gutjnl-2016-311739, PubMed 27406039
3. Jørgensen SF, Trøseid M, Kummen M, Anmarkrud JA, Michelsen AE, Osnes LT, Holm K, Høivik ML, Rashidi A, Dahl CP, Vesterhus M, Halvorsen B, Mollnes TE, Berge RK, Moum B, Lundin KE, Fevang B, Ueland T, Karlsen TH, Aukrust P, Hov JR (2016)
   Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
   Mucosal Immunol, 9 (6), 1455-1465
   DOI 10.1038/mi.2016.18, PubMed 26982597
4. Knudsen A, Christensen TE, Thorsteinsson K, Ghotbi AA, Hasbak P, Lebech AM, Nielsen SD, Hov JR, Berge R, Ripa RS, Kjær A, Trøseid M (2016)
   Microbiota-Dependent Marker TMAO is Not Associated With Decreased Myocardial Perfusion in Well-Treated HIV-Infected Patients as Assessed by 82Rubidium PET/CT
   J Acquir Immune Defic Syndr, 72 (4), e83-5
   DOI 10.1097/QAI.0000000000001044, PubMed 27152465
5. Kummen M, Holm K, Anmarkrud JA, Nygård S, Vesterhus M, Høivik ML, Trøseid M, Marschall HU, Schrumpf E, Moum B, Røsjø H, Aukrust P, Karlsen TH, Hov JR (2016)
   The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
   Gut, 66 (4), 611-619
   DOI 10.1136/gutjnl-2015-310500, PubMed 26887816
6. Kummen M, Hov JR (2016)
   Response to 'Faecal microbiota profiles as diagnostic biomarkers in primary sclerosing cholangitis' by Rühlemann et al
   Gut, 66 (4), 755-756
   DOI 10.1136/gutjnl-2016-312347, PubMed 27340191
7. Kummen M, Vesterhus M, Trøseid M, Moum B, Svardal A, Boberg KM, Aukrust P, Karlsen TH, Berge RK, Hov JR (2016)
   Elevated trimethylamine-N-oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function
   United European Gastroenterol J, 5 (4), 532-541
   DOI 10.1177/2050640616663453, PubMed 28588885
8. Lunder AK, Hov JR, Borthne A, Gleditsch J, Johannesen G, Tveit K, Viktil E, Henriksen M, Hovde Ø, Huppertz-Hauss G, Høie O, Høivik ML, Monstad I, Solberg IC, Jahnsen J, Karlsen TH, Moum B, Vatn M, Negård A (2016)
   Prevalence of Sclerosing Cholangitis Detected by Magnetic Resonance Cholangiography in Patients With Long-term Inflammatory Bowel Disease
   Gastroenterology, 151 (4), 660-669.e4
   DOI 10.1053/j.gastro.2016.06.021, PubMed 27342213
9. Schrumpf E, Kummen M, Valestrand L, Greiner TU, Holm K, Arulampalam V, Reims HM, Baines J, Bäckhed F, Karlsen TH, Blumberg RS, Hov JR, Melum E (2016)
   The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation
   J Hepatol, 66 (2), 382-389
   DOI 10.1016/j.jhep.2016.09.020, PubMed 27720803
10. Skagen K, Trøseid M, Ueland T, Holm S, Abbas A, Gregersen I, Kummen M, Bjerkeli V, Reier-Nilsen F, Russell D, Svardal A, Karlsen TH, Aukrust P, Berge RK, Hov JE, Halvorsen B, Skjelland M (2016)
    The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis
    Atherosclerosis, 247, 64-9
    DOI 10.1016/j.atherosclerosis.2016.01.033, PubMed 26868510
11. Trøseid M, Hov JR, Nestvold TK, Thoresen H, Berge RK, Svardal A, Lappegård KT (2016)
    Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery
    Metab Syndr Relat Disord, 14 (4), 197-201
    DOI 10.1089/met.2015.0120, PubMed 27081744
12. Wang J, Thingholm LB, Skiecevičienė J, Rausch P, Kummen M, Hov JR, Degenhardt F, Heinsen FA, Rühlemann MC, Szymczak S, Holm K, Esko T, Sun J, Pricop-Jeckstadt M, Al-Dury S, Bohov P, Bethune J, Sommer F, Ellinghaus D, Berge RK, Hübenthal M, Koch M, Schwarz K, Rimbach G, Hübbe P et al. (2016)
    Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota
    Nat Genet, 48 (11), 1396-1406
    DOI 10.1038/ng.3695, PubMed 27723756
13. Zweers SJ, Shiryaev A, Komuta M, Vesterhus M, Hov JR, Perugorria MJ, de Waart DR, Chang JC, Tol S, Te Velde AA, de Jonge WJ, Banales JM, Roskams T, Beuers U, Karlsen TH, Jansen PL, Schaap FG (2016)
    Elevated interleukin-8 in bile of patients with primary sclerosing cholangitis
    Liver Int, 36 (9), 1370-7
    DOI 10.1111/liv.13092, PubMed 26866350

Publications 2015

1. Berntsen NL, Klingenberg O, Juran BD, Benito de Valle M, Lindkvist B, Lazaridis KN, Boberg KM, Karlsen TH, Hov JR (2015)
   Association Between HLA Haplotypes and Increased Serum Levels of IgG4 in Patients With Primary Sclerosing Cholangitis
   Gastroenterology, 148 (5), 924-927.e2
   DOI 10.1053/j.gastro.2015.01.041, PubMed 25655558
2. Carpino G, Cardinale V, Renzi A, Hov JR, Berloco PB, Rossi M, Karlsen TH, Alvaro D, Gaudio E (2015)
   Activation of biliary tree stem cells within peribiliary glands in primary sclerosing cholangitis
   J Hepatol, 63 (5), 1220-8
   DOI 10.1016/j.jhep.2015.06.018, PubMed 26119688
3. Cleynen I, Boucher G, Jostins L, Schumm LP, Zeissig S, Ahmad T, Andersen V, Andrews JM, Annese V, Brand S, Brant SR, Cho JH, Daly MJ, Dubinsky M, Duerr RH, Ferguson LR, Franke A, Gearry RB, Goyette P, Hakonarson H, Halfvarson J, Hov JR, Huang H, Kennedy NA, Kupcinskas L et al. (2015)
   Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
   Lancet, 387 (10014), 156-67
   DOI 10.1016/S0140-6736(15)00465-1, PubMed 26490195
4. Hov JE, Trøseid M (2015)
   Personalised medicine targeting the gut microbiota?
   Tidsskr Nor Laegeforen, 135 (7), 624
   DOI 10.4045/tidsskr.14.1431, PubMed 25899345
5. Hov JER, Troseid M (2015)
   Personalized intestinal flora medicine?
   Tidsskr. Nor. Laegeforen., 135 (7), 624
6. Hov JR, Zhong H, Qin B, Anmarkrud JA, Holm K, Franke A, Lie BA, Karlsen TH (2015)
   The Influence of the Autoimmunity-Associated Ancestral HLA Haplotype AH8.1 on the Human Gut Microbiota: A Cross-Sectional Study
   PLoS One, 10 (7), e0133804
   DOI 10.1371/journal.pone.0133804, PubMed 26207384
7. Kevans D, Tyler AD, Holm K, Jørgensen KK, Vatn MH, Karlsen TH, Kaplan GG, Eksteen B, Gevers D, Hov JR, Silverberg MS (2015)
   Characterization of Intestinal Microbiota in Ulcerative Colitis Patients with and without Primary Sclerosing Cholangitis
   J Crohns Colitis, 10 (3), 330-7
   DOI 10.1093/ecco-jcc/jjv204, PubMed 26526357
8. Liaskou E, Klemsdal Henriksen EK, Holm K, Kaveh F, Hamm D, Fear J, Viken MK, Hov JR, Melum E, Robins H, Olweus J, Karlsen TH, Hirschfield GM (2015)
   High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires
   Hepatology, 63 (5), 1608-19
   DOI 10.1002/hep.28116, PubMed 26257205
9. Nowak P, Troseid M, Avershina E, Barqasho B, Neogi U, Holm K, Hov JR, Noyan K, Vesterbacka J, Svärd J, Rudi K, Sönnerborg A (2015)
   Gut microbiota diversity predicts immune status in HIV-1 infection
   AIDS, 29 (18), 2409-18
   DOI 10.1097/QAD.0000000000000869, PubMed 26355675
10. Stiksrud B, Nowak P, Nwosu FC, Kvale D, Thalme A, Sonnerborg A, Ueland PM, Holm K, Birkeland SE, Dahm AE, Sandset PM, Rudi K, Hov JR, Dyrhol-Riise AM, Trøseid M (2015)
    Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART
    J Acquir Immune Defic Syndr, 70 (4), 329-37
    DOI 10.1097/QAI.0000000000000784, PubMed 26258571
11. Vesterhus M, Hov JR, Holm A, Schrumpf E, Nygård S, Godang K, Andersen IM, Naess S, Thorburn D, Saffioti F, Vatn M, Gilja OH, Lund-Johansen F, Syversveen T, Brabrand K, Parés A, Ponsioen CY, Pinzani M, Färkkilä M, Moum B, Ueland T, Røsjø H, Rosenberg W, Boberg KM, Karlsen TH (2015)
    Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis
    Hepatology, 62 (1), 188-97
    DOI 10.1002/hep.27825, PubMed 25833813
12. Wannhoff A, Folseraas T, Brune M, Rupp C, Friedrich K, Knierim J, Weiss KH, Sauer P, Flechtenmacher C, Schirmacher P, Stremmel W, Hov JR, Gotthardt DN (2015)
    A common genetic variant of fucosyltransferase 2 correlates with serum carcinoembryonic antigen levels and affects cancer screening in patients with primary sclerosing cholangitis
    United European Gastroenterol J, 4 (1), 84-91
    DOI 10.1177/2050640615581577, PubMed 26966527
13. Wannhoff A, Rupp C, Friedrich K, Brune M, Knierim J, Flechtenmacher C, Sauer P, Stremmel W, Hov JR, Schirmacher P, Weiss KH, Gotthardt DN (2015)
    Inflammation But Not Biliary Obstruction Is Associated With Carbohydrate Antigen 19-9 Levels in Patients With Primary Sclerosing Cholangitis
    Clin Gastroenterol Hepatol, 13 (13), 2372-9
    DOI 10.1016/j.cgh.2015.07.014, PubMed 26192140
14. Wittig M, Anmarkrud JA, Kässens JC, Koch S, Forster M, Ellinghaus E, Hov JR, Sauer S, Schimmler M, Ziemann M, Görg S, Jacob F, Karlsen TH, Franke A (2015)
    Development of a high-resolution NGS-based HLA-typing and analysis pipeline
    Nucleic Acids Res, 43 (11), e70
    DOI 10.1093/nar/gkv184, PubMed 25753671

Publications 2014

1. Fosby B, Næss S, Hov JR, Traherne J, Boberg KM, Trowsdale J, Foss A, Line PD, Franke A, Melum E, Scott H, Karlsen TH (2014)
   HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation
   World J Gastroenterol, 20 (14), 3986-4000
   DOI 10.3748/wjg.v20.i14.3986, PubMed 24744588
2. Friedrich K, Wannhoff A, Kattner S, Brune M, Hov JR, Weiss KH, Antoni C, Dollinger M, Neumann-Haefelin C, Seufferlein T, Schemmer P, Schirmacher P, Stremmel W, Gotthardt DN (2014)
   PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival
   J Gastroenterol Hepatol, 29 (7), 1477-84
   DOI 10.1111/jgh.12540, PubMed 25273282
3. Naess S, Björnsson E, Anmarkrud JA, Al Mamari S, Juran BD, Lazaridis KN, Chapman R, Bergquist A, Melum E, Marsh SG, Schrumpf E, Lie BA, Boberg KM, Karlsen TH, Hov JR (2014)
   Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease
   Liver Int, 34 (10), 1488-95
   DOI 10.1111/liv.12492, PubMed 24517468
4. Næss S, Lie BA, Melum E, Olsson M, Hov JR, Croucher PJ, Hampe J, Thorsby E, Bergquist A, Traherne JA, Schrumpf E, Boberg KM, Schreiber S, Franke A, Karlsen TH (2014)
   Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population
   PLoS One, 9 (12), e114486
   DOI 10.1371/journal.pone.0114486, PubMed 25521205
5. Trøseid M, Ueland T, Hov JR, Svardal A, Gregersen I, Dahl CP, Aakhus S, Gude E, Bjørndal B, Halvorsen B, Karlsen TH, Aukrust P, Gullestad L, Berge RK, Yndestad A (2014)
   Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure
   J Intern Med, 277 (6), 717-26
   DOI 10.1111/joim.12328, PubMed 25382824

Publications 2013

1. Andersen IM, Tengesdal G, Lie BA, Boberg KM, Karlsen TH, Hov JR (2013)
   Effects of coffee consumption, smoking, and hormones on risk for primary sclerosing cholangitis
   Clin Gastroenterol Hepatol, 12 (6), 1019-28
   DOI 10.1016/j.cgh.2013.09.024, PubMed 24076415
2. Ellinghaus D, Folseraas T, Holm K, Ellinghaus E, Melum E, Balschun T, Laerdahl JK, Shiryaev A, Gotthardt DN, Weismüller TJ, Schramm C, Wittig M, Bergquist A, Björnsson E, Marschall HU, Vatn M, Teufel A, Rust C, Gieger C, Wichmann HE, Runz H, Sterneck M, Rupp C, Braun F, Weersma RK et al. (2013)
   Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4
   Hepatology, 58 (3), 1074-83
   DOI 10.1002/hep.25977, PubMed 22821403
3. Friedrich K, Rupp C, Hov JR, Steinebrunner N, Weiss KH, Stiehl A, Brune M, Schaefer PK, Schemmer P, Sauer P, Schirmacher P, Runz H, Karlsen TH, Stremmel W, Gotthardt DN (2013)
   A frequent PNPLA3 variant is a sex specific disease modifier in PSC patients with bile duct stenosis
   PLoS One, 8 (3), e58734
   DOI 10.1371/journal.pone.0058734, PubMed 23505555
4. Liu JZ, Hov JR, Folseraas T, Ellinghaus E, Rushbrook SM, Doncheva NT, Andreassen OA, Weersma RK, Weismüller TJ, Eksteen B, Invernizzi P, Hirschfield GM, Gotthardt DN, Pares A, Ellinghaus D, Shah T, Juran BD, Milkiewicz P, Rust C, Schramm C, Müller T, Srivastava B, Dalekos G, Nöthen MM, Herms S et al. (2013)
   Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
   Nat Genet, 45 (6), 670-5
   DOI 10.1038/ng.2616, PubMed 23603763
5. Wannhoff A, Hov JR, Folseraas T, Rupp C, Friedrich K, Anmarkrud JA, Weiss KH, Sauer P, Schirmacher P, Boberg KM, Stremmel W, Karlsen TH, Gotthardt DN (2013)
   FUT2 and FUT3 genotype determines CA19-9 cut-off values for detection of cholangiocarcinoma in patients with primary sclerosing cholangitis
   J Hepatol, 59 (6), 1278-84
   DOI 10.1016/j.jhep.2013.08.005, PubMed 23958938

Publications 2012

1. Folseraas T, Melum E, Rausch P, Juran BD, Ellinghaus E, Shiryaev A, Laerdahl JK, Ellinghaus D, Schramm C, Weismüller TJ, Gotthardt DN, Hov JR, Clausen OP, Weersma RK, Janse M, Boberg KM, Björnsson E, Marschall HU, Cleynen I, Rosenstiel P, Holm K, Teufel A, Rust C, Gieger C, Wichmann HE et al. (2012)
   Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci
   J Hepatol, 57 (2), 366-75
   DOI 10.1016/j.jhep.2012.03.031, PubMed 22521342
2. Næss S, Shiryaev A, Hov JR, Franke A, Karlsen TH (2012)
   Genetics in primary sclerosing cholangitis
   Clin Res Hepatol Gastroenterol, 36 (4), 325-33
   DOI 10.1016/j.clinre.2012.02.003, PubMed 22554879

Publications 2011

1. Hov JR, Keitel V, Schrumpf E, Häussinger D, Karlsen TH (2011)
   TGR5 sequence variation in primary sclerosing cholangitis
   Dig Dis, 29 (1), 78-84
   DOI 10.1159/000324138, PubMed 21691110
2. Hov JR, Kosmoliaptsis V, Traherne JA, Olsson M, Boberg KM, Bergquist A, Schrumpf E, Bradley JA, Taylor CJ, Lie BA, Trowsdale J, Karlsen TH (2011)
   Electrostatic modifications of the human leukocyte antigen-DR P9 peptide-binding pocket and susceptibility to primary sclerosing cholangitis
   Hepatology, 53 (6), 1967-76
   DOI 10.1002/hep.24299, PubMed 21413052

Publications 2010

1. Hov JR, Keitel V, Laerdahl JK, Spomer L, Ellinghaus E, ElSharawy A, Melum E, Boberg KM, Manke T, Balschun T, Schramm C, Bergquist A, Weismüller T, Gotthardt D, Rust C, Henckaerts L, Onnie CM, Weersma RK, Sterneck M, Teufel A, Runz H, Stiehl A, Ponsioen CY, Wijmenga C, Vatn MH et al. (2010)
   Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis
   PLoS One, 5 (8), e12403
   DOI 10.1371/journal.pone.0012403, PubMed 20811628
2. Hov JR, Lleo A, Selmi C, Woldseth B, Fabris L, Strazzabosco M, Karlsen TH, Invernizzi P (2010)
   Genetic associations in Italian primary sclerosing cholangitis: heterogeneity across Europe defines a critical role for HLA-C
   J Hepatol, 52 (5), 712-7
   DOI 10.1016/j.jhep.2009.11.029, PubMed 20347497
3. Karlsen TH, Hov JR (2010)
   Genetics of cholestatic liver disease in 2010
   Curr Opin Gastroenterol, 26 (3), 251-8
   DOI 10.1097/MOG.0b013e328336807d, PubMed 20042859
4. Melum E, Franke A, Schramm C, Weismüller TJ, Gotthardt DN, Offner FA, Juran BD, Laerdahl JK, Labi V, Björnsson E, Weersma RK, Henckaerts L, Teufel A, Rust C, Ellinghaus E, Balschun T, Boberg KM, Ellinghaus D, Bergquist A, Sauer P, Ryu E, Hov JR, Wedemeyer J, Lindkvist B, Wittig M et al. (2010)
   Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci
   Nat Genet, 43 (1), 17-9
   DOI 10.1038/ng.728, PubMed 21151127

Publications 2009

1. Hov JR, Clench-Aas J, Bartonova A, Stavem K (2009)
   Agreement of a child's respiratory symptom diary with parental reports and peak expiratory flow
   Int J Tuberc Lung Dis, 13 (3), 400-6
   PubMed 19275804
2. Karlsen TH, Franke A, Melum E, Kaser A, Hov JR, Balschun T, Lie BA, Bergquist A, Schramm C, Weismüller TJ, Gotthardt D, Rust C, Philipp EE, Fritz T, Henckaerts L, Weersma RK, Stokkers P, Ponsioen CY, Wijmenga C, Sterneck M, Nothnagel M, Hampe J, Teufel A, Runz H, Rosenstiel P et al. (2009)
   Genome-wide association analysis in primary sclerosing cholangitis
   Gastroenterology, 138 (3), 1102-11
   DOI 10.1053/j.gastro.2009.11.046, PubMed 19944697

Publications 2008

1. Hov JR, Boberg KM, Karlsen TH (2008)
   Autoantibodies in primary sclerosing cholangitis
   World J Gastroenterol, 14 (24), 3781-91
   DOI 10.3748/wjg.14.3781, PubMed 18609700

Publications 2003

1. Røsjø HR, Hov JE, Borchsenius F, Skjønsberg OH (2003)
   [Wasp allergy vaccination]
   Tidsskr Nor Laegeforen, 123 (8), 1075-7
   PubMed 12760227