Brian K. Chung
- Postdoc; PhD
Publications 2024
Single-Cell Transcriptomic Profiling of Cholangiocyte Organoids Derived from Bile Ducts of Primary Sclerosing Cholangitis Patients
Dig Dis Sci (in press)
DOI 10.1007/s10620-024-08570-y, PubMed 39160386
Publications 2023
Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT
Hum Mol Genet, 32 (15), 2422-2440
DOI 10.1093/hmg/ddad062, PubMed 37129502
Cholangiocytes Modulate CD100 Expression in the Liver and Facilitate Pathogenic T-Helper 17 Cell Differentiation
Gastroenterology, 166 (4), 667-679
DOI 10.1053/j.gastro.2023.11.283, PubMed 37995866
Publications 2022
Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis
Hepatol Commun, 6 (9), 2538-2550
DOI 10.1002/hep4.2001, PubMed 35726350
Publications 2020
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393
Publications 2019
Complexity in unclassified auto-inflammatory disease: a case report illustrating the potential for disease arising from the allelic burden of multiple variants
Pediatr Rheumatol Online J, 17 (1), 70
DOI 10.1186/s12969-019-0374-x, PubMed 31660995
Publications 2018
Gut and Liver B Cells of Common Clonal Origin in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease
Hepatol Commun, 2 (8), 956-967
DOI 10.1002/hep4.1200, PubMed 30094406
Publications 2017
Immunogenetics in primary sclerosing cholangitis
Curr Opin Gastroenterol, 33 (2), 93-98
DOI 10.1097/MOG.0000000000000336, PubMed 28146446
Genetic Discoveries Highlight Environmental Factors as Key Drivers of Liver Disease
Dig Dis, 35 (4), 323-333
DOI 10.1159/000456583, PubMed 28468012
Cholangiocytes in the pathogenesis of primary sclerosing cholangitis and development of cholangiocarcinoma
Biochim Biophys Acta Mol Basis Dis, 1864 (4 Pt B), 1390-1400
DOI 10.1016/j.bbadis.2017.08.020, PubMed 28844951
Publications 2016
Phenotyping and auto-antibody production by liver-infiltrating B cells in primary sclerosing cholangitis and primary biliary cholangitis
J Autoimmun, 77, 45-54
DOI 10.1016/j.jaut.2016.10.003, PubMed 27784538
Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease
J Hepatol, 66 (1), 116-122
DOI 10.1016/j.jhep.2016.09.002, PubMed 27647428
Publications 2015
CD1d Expression and Invariant NKT Cell Responses in Herpesvirus Infections
Front Immunol, 6, 312
DOI 10.3389/fimmu.2015.00312, PubMed 26161082
Genetic Risk and the Development of Autoimmune Liver Disease
Dig Dis, 33 Suppl 2, 13-24
DOI 10.1159/000440706, PubMed 26641277
Publications 2014
Duplication of AKT3 is associated with macrocephaly and speech delay
Am J Med Genet A, 164A (7), 1868-9
DOI 10.1002/ajmg.a.36521, PubMed 24700746
Natural killer T cell strategies to combat Epstein-Barr virus infection
Oncoimmunology, 3, e28329
DOI 10.4161/onci.28329, PubMed 25050206
Publications 2013
Innate immune control of EBV-infected B cells by invariant natural killer T cells
Blood, 122 (15), 2600-8
DOI 10.1182/blood-2013-01-480665, PubMed 23974196
Publications 2011
CD1d and CD1c expression in human B cells is regulated by activation and retinoic acid receptor signaling
J Immunol, 186 (9), 5261-72
DOI 10.4049/jimmunol.1003615, PubMed 21451111
Publications 2009
Apolipoprotein-mediated lipid antigen presentation in B cells provides a pathway for innate help by NKT cells
Blood, 114 (12), 2411-6
DOI 10.1182/blood-2009-04-211417, PubMed 19620401