Brian K. Chung

  • Postdoc; PhD
 

Publications 2024

Frank AK, Chung BK, De Novales MLL, Engesæter LK, Hoyle HW, Øgaard J, Heslop J, Karlsen TH, Tysoe O, Brevini T, Tchorz JS, Vallier L, Mohorianu I, Sampaziotis F, Melum E (2024)
Single-Cell Transcriptomic Profiling of Cholangiocyte Organoids Derived from Bile Ducts of Primary Sclerosing Cholangitis Patients
Dig Dis Sci (in press)
DOI 10.1007/s10620-024-08570-y, PubMed 39160386

Publications 2023

Al Khatib I, Deng J, Lei Y, Torres-Odio S, Rojas GR, Newman LE, Chung BK, Symes A, Zhang H, Huang SN, Pommier Y, Khan A, Shadel GS, West AP, Gibson WT, Shutt TE (2023)
Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT
Hum Mol Genet, 32 (15), 2422-2440
DOI 10.1093/hmg/ddad062, PubMed 37129502

Jiang X, Otterdal K, Chung BK, Maucourant C, Rønneberg JD, Zimmer CL, Øgaard J, Boichuk Y, Holm S, Geanon D, Schneditz G, Bergquist A, Björkström NK, Melum E (2023)
Cholangiocytes Modulate CD100 Expression in the Liver and Facilitate Pathogenic T-Helper 17 Cell Differentiation
Gastroenterology, 166 (4), 667-679
DOI 10.1053/j.gastro.2023.11.283, PubMed 37995866

Publications 2022

Chung BK, Øgaard J, Reims HM, Karlsen TH, Melum E (2022)
Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis
Hepatol Commun, 6 (9), 2538-2550
DOI 10.1002/hep4.2001, PubMed 35726350

Publications 2020

Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393

Publications 2019

Tucker LB, Lamot L, Niemietz I, Chung BK, Cabral DA, Houghton K, Petty RE, Morishita KA, Rice GI, Turvey SE, Gibson WT, Brown KL (2019)
Complexity in unclassified auto-inflammatory disease: a case report illustrating the potential for disease arising from the allelic burden of multiple variants
Pediatr Rheumatol Online J, 17 (1), 70
DOI 10.1186/s12969-019-0374-x, PubMed 31660995

Publications 2018

Chung BK, Henriksen EKK, Jørgensen KK, Karlsen TH, Hirschfield GM, Liaskou E (2018)
Gut and Liver B Cells of Common Clonal Origin in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease
Hepatol Commun, 2 (8), 956-967
DOI 10.1002/hep4.1200, PubMed 30094406

Publications 2017

Chung BK, Hirschfield GM (2017)
Immunogenetics in primary sclerosing cholangitis
Curr Opin Gastroenterol, 33 (2), 93-98
DOI 10.1097/MOG.0000000000000336, PubMed 28146446

Chung BK, Karlsen TH (2017)
Genetic Discoveries Highlight Environmental Factors as Key Drivers of Liver Disease
Dig Dis, 35 (4), 323-333
DOI 10.1159/000456583, PubMed 28468012

Chung BK, Karlsen TH, Folseraas T (2017)
Cholangiocytes in the pathogenesis of primary sclerosing cholangitis and development of cholangiocarcinoma
Biochim Biophys Acta Mol Basis Dis, 1864 (4 Pt B), 1390-1400
DOI 10.1016/j.bbadis.2017.08.020, PubMed 28844951

Publications 2016

Chung BK, Guevel BT, Reynolds GM, Gupta Udatha DB, Henriksen EK, Stamataki Z, Hirschfield GM, Karlsen TH, Liaskou E (2016)
Phenotyping and auto-antibody production by liver-infiltrating B cells in primary sclerosing cholangitis and primary biliary cholangitis
J Autoimmun, 77, 45-54
DOI 10.1016/j.jaut.2016.10.003, PubMed 27784538

Henriksen EK, Jørgensen KK, Kaveh F, Holm K, Hamm D, Olweus J, Melum E, Chung BK, Eide TJ, Lundin KE, Boberg KM, Karlsen TH, Hirschfield GM, Liaskou E (2016)
Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease
J Hepatol, 66 (1), 116-122
DOI 10.1016/j.jhep.2016.09.002, PubMed 27647428

Publications 2015

Chung BK, Priatel JJ, Tan R (2015)
CD1d Expression and Invariant NKT Cell Responses in Herpesvirus Infections
Front Immunol, 6, 312
DOI 10.3389/fimmu.2015.00312, PubMed 26161082

Karlsen TH, Chung BK (2015)
Genetic Risk and the Development of Autoimmune Liver Disease
Dig Dis, 33 Suppl 2, 13-24
DOI 10.1159/000440706, PubMed 26641277

Publications 2014

Chung BK, Eydoux P, Van Karnebeek CD, Gibson WT (2014)
Duplication of AKT3 is associated with macrocephaly and speech delay
Am J Med Genet A, 164A (7), 1868-9
DOI 10.1002/ajmg.a.36521, PubMed 24700746

Priatel JJ, Chung BK, Tsai K, Tan R (2014)
Natural killer T cell strategies to combat Epstein-Barr virus infection
Oncoimmunology, 3, e28329
DOI 10.4161/onci.28329, PubMed 25050206

Publications 2013

Chung BK, Tsai K, Allan LL, Zheng DJ, Nie JC, Biggs CM, Hasan MR, Kozak FK, van den Elzen P, Priatel JJ, Tan R (2013)
Innate immune control of EBV-infected B cells by invariant natural killer T cells
Blood, 122 (15), 2600-8
DOI 10.1182/blood-2013-01-480665, PubMed 23974196

Publications 2011

Allan LL, Stax AM, Zheng DJ, Chung BK, Kozak FK, Tan R, van den Elzen P (2011)
CD1d and CD1c expression in human B cells is regulated by activation and retinoic acid receptor signaling
J Immunol, 186 (9), 5261-72
DOI 10.4049/jimmunol.1003615, PubMed 21451111

Publications 2009

Allan LL, Hoefl K, Zheng DJ, Chung BK, Kozak FK, Tan R, van den Elzen P (2009)
Apolipoprotein-mediated lipid antigen presentation in B cells provides a pathway for innate help by NKT cells
Blood, 114 (12), 2411-6
DOI 10.1182/blood-2009-04-211417, PubMed 19620401

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