Mehrdad Rakaee

  • Senior Researcher; PhD
 

Publications 2021

Rakaee M, Kilvaer TK, Jamaly S, Berg T, Paulsen EE, Berglund M, Richardsen E, Andersen S, Al-Saad S, Poehl M, Pezzella F, Kwiatkowski DJ, Bremnes RM, Busund LTR, Donnem T (2021)
Tertiary lymphoid structure score: a promising approach to refine the TNM staging in resected non-small cell lung cancer
Br. J. Cancer, 124 (10), 1680-1689
DOI 10.1038/s41416-021-01307-y

Ramberg H, Richardsen E, de Souza GA, Rakaee M, Stensland ME, Braadland PR, Nygard S, Ogren O, Guldvik IJ, Berge V, Svindland A, Tasken KA, Andersen S (2021)
Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
Carcinogenesis, 42 (5), 685-693
DOI 10.1093/carcin/bgab015

Stoen MJ, Andersen S, Rakaee M, Pedersen MI, Ingebriktsen LM, Donnem T, Lombardi APG, Kilvaer TK, Busund LTR, Richardsen E (2021)
Overexpression of miR-20a-5p in Tumor Epithelium Is an Independent Negative Prognostic Indicator in Prostate Cancer-A Multi-Institutional Study
Cancers, 13 (16), 4096
DOI 10.3390/cancers13164096

Publications 2020

Kilvaer TK, Paulsen EE, Andersen S, Rakaee M, Bremnes RM, Busund LTR, Donnem T (2020)
Digitally quantified CD8(+) cells: the best candidate marker for an immune cell score in non-small cell lung cancer?
Carcinogenesis, 41 (12), 1671-1681
DOI 10.1093/carcin/bgaa105

Publications 2019

Kilvaer TK, Rakaee M, Hellevik T, Vik J, De Petris L, Donnem T, Strell C, Ostman A, Busund LTR, Martinez-Zubiaurre I (2019)
Differential prognostic impact of platelet-derived growth factor receptor expression in NSCLC
Sci Rep, 9, 10163
DOI 10.1038/s41598-019-46510-3

Rakaee M, Busund LTR, Jamaly S, Paulsen EE, Richardsen E, Andersen S, Al-Saad S, Bremnes RM, Donnem T, Kilvaer TK (2019)
Prognostic Value of Macrophage Phenotypes in Resectable Non-Small Cell Lung Cancer Assessed by Multiplex Immunohistochemistry
Neoplasia, 21 (3), 282-293
DOI 10.1016/j.neo.2019.01.005

Richardsen E, Andersen S, Melbo-Jorgensen C, Rakaee M, Ness N, Al-Saad S, Nordby Y, Pedersen MI, Donnem T, Bremnes RM, Busund LT (2019)
MicroRNA 141 is associated to outcome and aggressive tumor characteristics in prostate cancer
Sci Rep, 9, 386
DOI 10.1038/s41598-018-36854-7

Publications 2018

Grindstad T, Richardsen E, Andersen S, Skjefstad K, Khanehkenari MR, Donnem T, Ness N, Nordby Y, Bremnes RM, Al-Saad S, Busund LT (2018)
Progesterone Receptors in Prostate Cancer: Progesterone receptor B is the isoform associated with disease progression
Sci Rep, 8, 11358
DOI 10.1038/s41598-018-29520-5

Hald SM, Rakaee M, Martinez I, Richardsen E, Al-Saad S, Paulsen EE, Blix ES, Kilvaer T, Andersen S, Busund LT, Bremnes RM, Donnem T (2018)
LAG-3 in Non-Small-cell Lung Cancer: Expression in Primary Tumors and Metastatic Lymph Nodes Is Associated With Improved Survival
Clin. Lung Cancer, 19 (3), 249-+
DOI 10.1016/j.cllc.2017.12.001

Kilvaer TK, Rakaee M, Hellevik T, Ostman A, Strell C, Bremnes RM, Busund LT, Donnem T, Martinez-Zubiaurre I (2018)
Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer
PLoS One, 13 (2), e0192157
DOI 10.1371/journal.pone.0192157

Rakaee M, Kilvaer TK, Dalen SM, Richardsen E, Paulsen EE, Hald SM, Al-Saad S, Andersen S, Donnem T, Bremnes RM, Busund LT (2018)
Evaluation of tumor-infiltrating lymphocytes using routine H&E slides predicts patient survival in resected non-small cell lung cancer
Hum. Pathol., 79, 188-198
DOI 10.1016/j.humpath.2018.05.017

Skjefstad K, Grindstad T, Khanehkenari MR, Richardsen E, Donnem T, Kilvaer T, Andersen S, Bremnes RM, Busund LT, Al-Saad S (2018)
Prognostic relevance of estrogen receptor alpha, beta and aromatase expression in non-small cell lung cancer (vol 113, pg 5, 2016)
Steroids, 130, 36-37
DOI 10.1016/j.steroids.2017.11.010

Publications 2017

Al-Saad S, Richardsen E, Kilvaer TK, Donnem T, Andersen S, Khanehkenari M, Bremnes RM, Busund LT (2017)
The impact of MET, IGF-1, IGF1R expression and EGFR mutations on survival of patients with non-small-cell lung cancer
PLoS One, 12 (7), e0181527
DOI 10.1371/journal.pone.0181527

Andersen S, Richardsen E, Rakaee M, Bertilsson H, Bremnes R, Borset M, Busund LT, Slordahl T (2017)
Expression of phosphatase of regenerating liver (PRL)-3, is independently associated with biochemical failure, clinical failure and death in prostate cancer
PLoS One, 12 (11), e0189000
DOI 10.1371/journal.pone.0189000

Ness N, Andersen S, Khanehkenari MR, Nordbakken CV, Valkov A, Paulsen EE, Nordby Y, Bremnes RM, Donnem T, Busund LT, Richardsen E (2017)
The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort
Oncotarget, 8 (16), 26789-26801
DOI 10.18632/oncotarget.15817

Nordby Y, Richardsen E, Rakaee M, Ness N, Donnem T, Patel HRH, Busund LT, Bremnes RM, Andersen S (2017)
High expression of PDGFR-beta in prostate cancer stroma is independently associated with clinical and biochemical prostate cancer recurrence
Sci Rep, 7, 43378
DOI 10.1038/srep43378

Paulsen EE, Kilvaer TK, Khanehkenari MR, Al-Saad S, Hald SM, Andersen S, Richardsen E, Ness N, Busund LT, Bremnes RM, Donnem T (2017)
Assessing PDL-1 and PD-1 in NoneSmall Cell Lung Cancer: A Novel Immunoscore Approach
Clin. Lung Cancer, 18 (2), 220-+
DOI 10.1016/j.cllc.2016.09.009

Paulsen EE, Kilvaer TK, Rakaee M, Richardsen E, Hald SM, Andersen S, Busund LT, Bremnes RM, Donnem T (2017)
CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases
Cancer Immunol. Immunother., 66 (11), 1449-1461
DOI 10.1007/s00262-017-2039-2

Richardsen E, Andersen S, Al-Saad S, Rakaee M, Nordby Y, Pedersen MI, Ness N, Grindstad T, Movik I, Donnem T, Bremnes R, Busund LT (2017)
Evaluation of the proliferation marker Ki-67 in a large prostatectomy cohort
PLoS One, 12 (11), e0186852
DOI 10.1371/journal.pone.0186852

Publications 2016

Bremnes RM, Busund LT, Kilvaer TL, Andersen S, Richardsen E, Paulsen EE, Hald S, Khanehkenari MR, Cooper WA, Kao SC, Donnem T (2016)
The Role of Tumor-Infiltrating Lymphocytes in Development, Progression, and Prognosis of Non-Small Cell Lung Cancer
J. Thorac. Oncol., 11 (6), 789-800
DOI 10.1016/j.jtho.2016.01.015

Grindstad T, Skjefstad K, Andersen S, Ness N, Nordby Y, Al-Saad S, Fismen S, Donnem T, Khanehkenari MR, Busund LT, Bremnes RM, Richardsen E (2016)
Estrogen receptors alpha and beta and aromatase as independent predictors for prostate cancer outcome
Sci Rep, 6, 33114
DOI 10.1038/srep33114

Kilvaer TK, Paulsen EE, Khanehkenari MR, Al-Saad S, Johansen RM, Al-Shibli K, Bremnes RM, Busund LT, Donnem T (2016)
The presence of intraepithelial CD45RO+cells in resected lymph nodes with metastases from NSCLC patients is an independent predictor of disease-specific survival
Br. J. Cancer, 114 (10), 1145-1151
DOI 10.1038/bjc.2016.92

Rakaee M, Busund LT, Paulsen EE, Richardsen E, Al-Saad S, Andersen S, Donnem T, Bremnes RM, Kilvaer TK (2016)
Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer
Oncotarget, 7 (44), 72184-72196
DOI 10.18632/oncotarget.12360

Skjefstad K, Grindstad T, Khanehkenari MR, Richardsen E, Donnem T, Kilvaer T, Andersen S, Bremnes RM, Busund LT, Al-Saad S (2016)
Prognostic relevance of estrogen receptor a, 3 and aromatase expression in non-small cell lung cancer
Steroids, 113, 5-13
DOI 10.1016/j.steroids.2016.05.008

Publications 2015

Kilvaer TK, Khanehkenari MR, Hellevik T, Al-Saad S, Paulsen EE, Bremnes RM, Busund LT, Donnem T, Martinez IZ (2015)
Cancer Associated Fibroblasts in Stage I-IIIA NSCLC: Prognostic Impact and Their Correlations with Tumor Molecular Markers
PLoS One, 10 (8), e0134965
DOI 10.1371/journal.pone.0134965

Paulsen EE, Kilvaer T, Khanehkenari MR, Maurseth RJ, Al-Saad S, Hald SM, Al-Shibli K, Andersen S, Richardsen E, Busund LT, Bremnes R, Donnem T (2015)
CD45RO (+) Memory T Lymphocytes - a Candidate Marker for TNM-Immunoscore in Squamous Non-Small Cell Lung Cancer
Neoplasia, 17 (11), 839-848
DOI 10.1016/j.neo.2015.11.004