Publications 2025

Førde D, Kilvær T, Pedersen MI, Lombardi AP, D'arsiè I, Paulsen EE, Busund LR, Rakaee M, Dønnem T, Andersen S (2025)
Prognostic impact of miR-17-5p and miR-20a-5p in NSCLC diverge in subgroups according to lymph node status
15, 1606933
DOI 10.3389/fonc.2025.1606933, PubMed 41079079

Nassar AH, Kim C, Adeyelu T, Bou Farhat E, Abushukair H, Rakaee M, Matteson K, Lau SF, Takabe Y, Ocejo A, Ardeshir-Larijani F, Leal T, Ramalingam S, Alam S, Gray JE, Hicks J, Kaldas D, Baena J, Berjaga MZ, Nana FA, Grohe C, Leuders H, Citarella F, Cortellini A, Mingo EC et al. (2025)
Integrated molecular and clinical characterization of pulmonary large cell neuroendocrine carcinoma
16 (1), 7717
DOI 10.1038/s41467-025-63091-0, PubMed 40830141

Rakaee M, Tafavvoghi M, Ricciuti B, Alessi JV, Cortellini A, Citarella F, Nibid L, Perrone G, Adib E, Fulgenzi CAM, Hidalgo Filho CM, Di Federico A, Jabar F, Hashemi S, Houda I, Richardsen E, Rasmussen Busund LT, Donnem T, Bahce I, Pinato DJ, Helland Å, Sholl LM, Awad MM, Kwiatkowski DJ (2025)
Deep Learning Model for Predicting Immunotherapy Response in Advanced Non-Small Cell Lung Cancer
11 (2), 109-118
DOI 10.1001/jamaoncol.2024.5356, PubMed 39724105

Scheiner B, Lombardi P, D'Alessio A, Kim G, Tafavvoghi M, Petrenko O, Goldin RD, Fulgenzi CAM, Torkpour A, Balcar L, Mauri FA, Pomej K, Himmelsbach V, Barsch M, Celsa C, Cabibbo G, Cheon J, Krall A, Hucke F, Di Tommaso L, Bernasconi M, Rimassa L, Samson A, Stefanini B, Mozayani B et al. (2025)
Preliminary qualification of a machine learning-based assessment of the tumor immune infiltrate as a predictor of outcome in patients with hepatocellular carcinoma treated with atezolizumab plus bevacizumab
13 (10)
DOI 10.1136/jitc-2024-010975, PubMed 41052886

Publications 2024

Tafavvoghi M, Sildnes A, Rakaee M, Shvetsov N, Bongo LA, Busund LR, Møllersen K (2024)
Deep learning-based classification of breast cancer molecular subtypes from H&E whole-slide images
16, 100410
DOI 10.1016/j.jpi.2024.100410, PubMed 39720418

Publications 2023

Nibid L, Greco C, Cordelli E, Sabarese G, Fiore M, Liu CZ, Ippolito E, Sicilia R, Miele M, Tortora M, Taffon C, Rakaee M, Soda P, Ramella S, Perrone G (2023)
Deep pathomics: A new image-based tool for predicting response to treatment in stage III non-small cell lung cancer
18 (11), e0294259
DOI 10.1371/journal.pone.0294259, PubMed 38015944

Rakaee M, Andersen S, Giannikou K, Paulsen EE, Kilvaer TK, Busund LR, Berg T, Richardsen E, Lombardi AP, Adib E, Pedersen MI, Tafavvoghi M, Wahl SGF, Petersen RH, Bondgaard AL, Yde CW, Baudet C, Licht P, Lund-Iversen M, Grønberg BH, Fjellbirkeland L, Helland Å, Pøhl M, Kwiatkowski DJ, Donnem T (2023)
Machine learning-based immune phenotypes correlate with STK11/KEAP1 co-mutations and prognosis in resectable NSCLC: a sub-study of the TNM-I trial
34 (7), 578-588
DOI 10.1016/j.annonc.2023.04.005, PubMed 37100205

Publications 2021

Jamaly S, Rakaee M, Abdi R, Tsokos GC, Fenton KA (2021)
Interplay of immune and kidney resident cells in the formation of tertiary lymphoid structures in lupus nephritis
20 (12), 102980
DOI 10.1016/j.autrev.2021.102980, PubMed 34718163

Rakaee M, Kilvaer TK, Jamaly S, Berg T, Paulsen EE, Berglund M, Richardsen E, Andersen S, Al-Saad S, Poehl M, Pezzella F, Kwiatkowski DJ, Bremnes RM, Busund LTR, Donnem T (2021)
Tertiary lymphoid structure score: a promising approach to refine the TNM staging in resected non-small cell lung cancer
Br. J. Cancer, 124 (10), 1680-1689
DOI 10.1038/s41416-021-01307-y

Ramberg H, Richardsen E, de Souza GA, Rakaee M, Stensland ME, Braadland PR, Nygård S, Ögren O, Guldvik IJ, Berge V, Svindland A, Taskén KA, Andersen S (2021)
Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
42 (5), 685-693
DOI 10.1093/carcin/bgab015, PubMed 33609362

Stoen MJ, Andersen S, Rakaee M, Pedersen MI, Ingebriktsen LM, Bremnes RM, Donnem T, Lombardi APG, Kilvaer TK, Busund LT, Richardsen E (2021)
High expression of miR-17-5p in tumor epithelium is a predictor for poor prognosis for prostate cancer patients
11 (1), 13864
DOI 10.1038/s41598-021-93208-6, PubMed 34226620

Stoen MJ, Andersen S, Rakaee M, Pedersen MI, Ingebriktsen LM, Donnem T, Lombardi APG, Kilvaer TK, Busund LR, Richardsen E (2021)
Overexpression of miR-20a-5p in Tumor Epithelium Is an Independent Negative Prognostic Indicator in Prostate Cancer-A Multi-Institutional Study
13 (16)
DOI 10.3390/cancers13164096, PubMed 34439249

Publications 2020

Kilvaer TK, Paulsen EE, Andersen S, Rakaee M, Bremnes RM, Busund LR, Donnem T (2020)
Digitally quantified CD8+ cells: the best candidate marker for an immune cell score in non-small cell lung cancer?
41 (12), 1671-1681
DOI 10.1093/carcin/bgaa105, PubMed 33035322

Publications 2019

Kilvaer TK, Rakaee M, Hellevik T, Vik J, Petris L, Donnem T, Strell C, Ostman A, Busund LR, Martinez-Zubiaurre I (2019)
Differential prognostic impact of platelet-derived growth factor receptor expression in NSCLC
9 (1), 10163
DOI 10.1038/s41598-019-46510-3, PubMed 31308421

Rakaee M, Busund LTR, Jamaly S, Paulsen EE, Richardsen E, Andersen S, Al-Saad S, Bremnes RM, Donnem T, Kilvaer TK (2019)
Prognostic Value of Macrophage Phenotypes in Resectable Non-Small Cell Lung Cancer Assessed by Multiplex Immunohistochemistry
Neoplasia, 21 (3), 282-293
DOI 10.1016/j.neo.2019.01.005

Richardsen E, Andersen S, Al-Saad S, Rakaee M, Nordby Y, Pedersen MI, Ness N, Ingebriktsen LM, Fassina A, Taskén KA, Mills IG, Donnem T, Bremnes RM, Busund LT (2019)
Low Expression of miR-424-3p is Highly Correlated with Clinical Failure in Prostate Cancer
9 (1), 10662
DOI 10.1038/s41598-019-47234-0, PubMed 31337863

Richardsen E, Andersen S, Melbo-Jorgensen C, Rakaee M, Ness N, Al-Saad S, Nordby Y, Pedersen MI, Donnem T, Bremnes RM, Busund LT (2019)
MicroRNA 141 is associated to outcome and aggressive tumor characteristics in prostate cancer
Sci Rep, 9, 386
DOI 10.1038/s41598-018-36854-7

Publications 2018

Grindstad T, Richardsen E, Andersen S, Skjefstad K, Rakaee Khanehkenari M, Donnem T, Ness N, Nordby Y, Bremnes RM, Al-Saad S, Busund LT (2018)
Progesterone Receptors in Prostate Cancer: Progesterone receptor B is the isoform associated with disease progression
8 (1), 11358
DOI 10.1038/s41598-018-29520-5, PubMed 30054508

Hald SM, Rakaee M, Martinez I, Richardsen E, Al-Saad S, Paulsen EE, Blix ES, Kilvaer T, Andersen S, Busund LT, Bremnes RM, Donnem T (2018)
LAG-3 in Non-Small-cell Lung Cancer: Expression in Primary Tumors and Metastatic Lymph Nodes Is Associated With Improved Survival
Clin. Lung Cancer, 19 (3), 249-+
DOI 10.1016/j.cllc.2017.12.001

Kilvaer TK, Rakaee M, Hellevik T, Ostman A, Strell C, Bremnes RM, Busund LT, Donnem T, Martinez-Zubiaurre I (2018)
Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer
PLoS One, 13 (2), e0192157
DOI 10.1371/journal.pone.0192157

Rakaee M, Kilvaer TK, Dalen SM, Richardsen E, Paulsen EE, Hald SM, Al-Saad S, Andersen S, Donnem T, Bremnes RM, Busund LT (2018)
Evaluation of tumor-infiltrating lymphocytes using routine H&E slides predicts patient survival in resected non-small cell lung cancer
Hum. Pathol., 79, 188-198
DOI 10.1016/j.humpath.2018.05.017

Publications 2017

Al-Saad S, Richardsen E, Kilvaer TK, Donnem T, Andersen S, Khanehkenari M, Bremnes RM, Busund LT (2017)
The impact of MET, IGF-1, IGF1R expression and EGFR mutations on survival of patients with non-small-cell lung cancer
12 (7), e0181527
DOI 10.1371/journal.pone.0181527, PubMed 28742836

Andersen S, Richardsen E, Rakaee M, Bertilsson H, Bremnes R, Borset M, Busund LT, Slordahl T (2017)
Expression of phosphatase of regenerating liver (PRL)-3, is independently associated with biochemical failure, clinical failure and death in prostate cancer
PLoS One, 12 (11), e0189000
DOI 10.1371/journal.pone.0189000

Ness N, Andersen S, Khanehkenari MR, Nordbakken CV, Valkov A, Paulsen EE, Nordby Y, Bremnes RM, Donnem T, Busund LT, Richardsen E (2017)
The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort
8 (16), 26789-26801
DOI 10.18632/oncotarget.15817, PubMed 28460462

Nordby Y, Richardsen E, Rakaee M, Ness N, Donnem T, Patel HRH, Busund LT, Bremnes RM, Andersen S (2017)
High expression of PDGFR-beta in prostate cancer stroma is independently associated with clinical and biochemical prostate cancer recurrence
Sci Rep, 7, 43378
DOI 10.1038/srep43378

Paulsen EE, Kilvaer TK, Rakaee M, Richardsen E, Hald SM, Andersen S, Busund LT, Bremnes RM, Donnem T (2017)
CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases
Cancer Immunol. Immunother., 66 (11), 1449-1461
DOI 10.1007/s00262-017-2039-2

Richardsen E, Andersen S, Al-Saad S, Rakaee M, Nordby Y, Pedersen MI, Ness N, Grindstad T, Movik I, Donnem T, Bremnes R, Busund LT (2017)
Evaluation of the proliferation marker Ki-67 in a large prostatectomy cohort
PLoS One, 12 (11), e0186852
DOI 10.1371/journal.pone.0186852

Skjefstad K, Grindstad T, Rakaee Khanehkenari M, Richardsen E, Donnem T, Kilvaer T, Andersen S, Bremnes RM, Busund LT, Al-Saad S (2017)
Corrigendum to "Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer" [Steroids 113 (2016) 5-13]
130, 36-37
DOI 10.1016/j.steroids.2017.11.010, PubMed 29273210

Publications 2016

Bremnes RM, Busund LT, Kilvær TL, Andersen S, Richardsen E, Paulsen EE, Hald S, Khanehkenari MR, Cooper WA, Kao SC, Dønnem T (2016)
The Role of Tumor-Infiltrating Lymphocytes in Development, Progression, and Prognosis of Non-Small Cell Lung Cancer
11 (6), 789-800
DOI 10.1016/j.jtho.2016.01.015, PubMed 26845192

Grindstad T, Skjefstad K, Andersen S, Ness N, Nordby Y, Al-Saad S, Fismen S, Donnem T, Khanehkenari MR, Busund LT, Bremnes RM, Richardsen E (2016)
Estrogen receptors α and β and aromatase as independent predictors for prostate cancer outcome
6, 33114
DOI 10.1038/srep33114, PubMed 27610593

Kilvaer TK, Paulsen EE, Khanehkenari MR, Al-Saad S, Johansen RM, Al-Shibli K, Bremnes RM, Busund LT, Donnem T (2016)
The presence of intraepithelial CD45RO+ cells in resected lymph nodes with metastases from NSCLC patients is an independent predictor of disease-specific survival
114 (10), 1145-51
DOI 10.1038/bjc.2016.92, PubMed 27167450

Paulsen EE, Kilvaer TK, Khanehkenari MR, Al-Saad S, Hald SM, Andersen S, Richardsen E, Ness N, Busund LT, Bremnes RM, Donnem T (2016)
Assessing PDL-1 and PD-1 in Non-Small Cell Lung Cancer: A Novel Immunoscore Approach
18 (2), 220-233.e8
DOI 10.1016/j.cllc.2016.09.009, PubMed 27816392

Rakaee M, Busund LT, Paulsen EE, Richardsen E, Al-Saad S, Andersen S, Donnem T, Bremnes RM, Kilvaer TK (2016)
Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer
Oncotarget, 7 (44), 72184-72196
DOI 10.18632/oncotarget.12360

Skjefstad K, Grindstad T, Khanehkenari MR, Richardsen E, Donnem T, Kilvaer T, Andersen S, Bremnes RM, Busund LT, Al-Saad S (2016)
Prognostic relevance of estrogen receptor α, β and aromatase expression in non-small cell lung cancer
113, 5-13
DOI 10.1016/j.steroids.2016.05.008, PubMed 27234503

Publications 2015

Kilvaer TK, Khanehkenari MR, Hellevik T, Al-Saad S, Paulsen EE, Bremnes RM, Busund LT, Donnem T, Martinez IZ (2015)
Cancer Associated Fibroblasts in Stage I-IIIA NSCLC: Prognostic Impact and Their Correlations with Tumor Molecular Markers
10 (8), e0134965
DOI 10.1371/journal.pone.0134965, PubMed 26252379

Paulsen EE, Kilvaer T, Khanehkenari MR, Maurseth RJ, Al-Saad S, Hald SM, Al-Shibli K, Andersen S, Richardsen E, Busund LT, Bremnes R, Donnem T (2015)
CD45RO(+) Memory T Lymphocytes--a Candidate Marker for TNM-Immunoscore in Squamous Non-Small Cell Lung Cancer
17 (11), 839-48
DOI 10.1016/j.neo.2015.11.004, PubMed 26678911

Publications 2012

Jamaly S, Khanehkenari MR, Rao R, Patil G, Thakur S, Ramaswamy P, Ajaikumar BS, Sahoo R (2012)
Relationship between p53 overexpression, human papillomavirus infection, and lifestyle in Indian patients with head and neck cancers
33 (2), 543-50
DOI 10.1007/s13277-011-0295-x, PubMed 22231431