The ASAC study, Scandinavian multicentre, placebo-controlled, randomized trial, initiated by our group, investigating the role of aspirin as adjuvant after surgery for colorectal liver metastases, is still recruiting patients and has now 300 of 800 patients included (www.asac.no). The trial is funded by Research Council of Norway, Norwegian Cancer Society, and KLINBEFORSK.
EXCALIBUR study; single centre, un-blinded, three-armed randomized trial for patients with high load of colorectal liver metastases, treated with 1)liver transplantation 2)liver resection 3)hepatic artery infusion of chemotherapy. The trial is approved by the Ethical committee and Norwegian Medicinal Agency and will to be initiated in 2021 (www.excaliburstudy.com).
Precision Medicine in Early Diagnostics and Therapy of Biliary Tract Cancer; is a collaborative project between several groups, led by Sheraz Yaqub, started December 2020.
TESLA trial: Liver Transplantation for Non-Resectable Intrahepatic Cholangiocarcinoma: a prospective exploratory trial; this is a collaborative study between several groups at OUH-KIT treating patients with cholangiocarcinoma
CAMINO study: Investigate the value of MRI in assessing CRC liver mets compared to CT scan, and if MRI affects the surgical decision.
Waage A, Khan A, Labori KJ, Birkeland KI, Scholz H, Jensen TG, Tholfsen T, Line PD, Hagness M(2024) Implementation of a nationwide program for total pancreatectomy and islet autotransplantation in chronic pancreatitis: A Scandinavian single-center observational study Scand J Surg, 14574969241298985(in press) DOI 10.1177/14574969241298985, PubMed 39558154
Amrutkar M, Guttorm SJT, Finstadsveen AV, Labori KJ, Eide L, Rootwelt H, Elgstøen KBP, Gladhaug IP, Verbeke CS(2024) Global metabolomic profiling of tumor tissue and paired serum samples to identify biomarkers for response to neoadjuvant FOLFIRINOX treatment of human pancreatic cancer Mol Oncol(in press) DOI 10.1002/1878-0261.13759, PubMed 39545923
Aune D, Nordsletten M, Myklebust TÅ, Robsahm TE, Skålhegg BS, Mala T, Yaqub S, Saeed U(2024) The association between body mass index and vulvar and vaginal cancer incidence: findings from a large Norwegian cohort study Cancer Causes Control(in press) DOI 10.1007/s10552-024-01930-z, PubMed 39463212