Stein Gunnar Larsen

  • MD; PhD
  • +47 2293 4052
 

Publications 2024

Dagenborg VJ, Brudvik KW, Lund-Andersen C, Torgunrud A, Lund-Iversen M, Flatmark K, Larsen SG, Yaqub S (2024)
Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy and Liver Resection is a Treatment Option for Patients With Peritoneal and Liver Metastases From Colorectal Cancer
Ann Surg, 280 (5), 745-752
DOI 10.1097/SLA.0000000000006492, PubMed 39185557

Fisher OM, Brown C, Esquivel J, Larsen SG, Liauw W, Alzahrani NA, Morris DL, Kepenekian V, Sourrouille I, Dumont F, Tuech JJ, Ceribelli C, Doussot B, Sgarbura O, Alhosni M, Quenet F, Glehen O, Cashin PH, (2024)
Hyperthermic intraperitoneal chemotherapy in colorectal cancer
BJS Open, 8 (3)
DOI 10.1093/bjsopen/zrae017, PubMed 38722737

Kongsgaard UE, Menchini RJ, Larsen SG, Juul-Hansen KE (2024)
Skin conductance algesimeter is unreliable during sudden perioperative temperature increases
Scand J Pain, 24 (1)
DOI 10.1515/sjpain-2023-0106, PubMed 38607365

Kongsgaard UE, Menchini RJ, Larsen SG, Juul-Hansen KE (2024)
Skin conductance algesimeter is unreliable during sudden perioperative temperature increase
Scand J Pain, 24 (1)
DOI 10.1515/sjpain-2024-0058, PubMed 39099226

Larsen SG, Graf W, Larsen RH, Revheim ME, Mariathasan AM, Sørensen O, Spasojevic M, Rashid G, Lundstrøm N, Gjertsen TJ, Aksnes AK, Bruland ØS (2024)
Eighteen-Months Safety and Efficacy Following Intraperitoneal Treatment With 224Radium-Labeled Microparticles After CRS-HIPEC in Patients With Peritoneal Metastasis From Colorectal Cancer
J Surg Oncol (in press)
DOI 10.1002/jso.27897, PubMed 39428687

Lund-Andersen C, Torgunrud A, Kanduri C, Dagenborg VJ, Frøysnes IS, Larsen MM, Davidson B, Larsen SG, Flatmark K (2024)
Novel drug resistance mechanisms and drug targets in BRAF-mutated peritoneal metastasis from colorectal cancer
J Transl Med, 22 (1), 646
DOI 10.1186/s12967-024-05467-2, PubMed 38982444

Publications 2023

Grønningsæter SR, Blakkisrud J, Selboe S, Revheim ME, Bruland ØS, Bønsdorff TB, Larsen SG, Stokke C (2023)
Radiation safety considerations for the use of radium-224-calciumcarbonate-microparticles in patients with peritoneal metastasis
Front Med (Lausanne), 10, 1058914
DOI 10.3389/fmed.2023.1058914, PubMed 36844217

Larsen SG, Graf W, Mariathasan AB, Sørensen O, Spasojevic M, Goscinski MA, Selboe S, Lundstrøm N, Holtermann A, Revheim ME, Bruland ØS (2023)
First experience with 224Radium-labeled microparticles (Radspherin®) after CRS-HIPEC for peritoneal metastasis in colorectal cancer (a phase 1 study)
Front Med (Lausanne), 10, 1070362
DOI 10.3389/fmed.2023.1070362, PubMed 36936230

Solbakken AM, Sellevold S, Spasojevic M, Julsrud L, Emblemsvåg HL, Reims HM, Sørensen O, Thorgersen EB, Fauske L, Ågren JSM, Brennhovd B, Ryder T, Larsen SG, Flatmark K (2023)
Navigation-Assisted Surgery for Locally Advanced Primary and Recurrent Rectal Cancer
Ann Surg Oncol, 30 (12), 7602-7611
DOI 10.1245/s10434-023-13964-9, PubMed 37481493

Thorgersen EB, Asvall J, Schjalm C, McAdam KE, Bruland ØS, Larsen SG, Mollnes TE (2023)
Effect of Intraperitoneal 224Radium-Labelled Microparticles on Compartmentalized Inflammation After Cytoreductive Surgery and Hypertherm Intraperitoneal Chemotherapy
Technol Cancer Res Treat, 22, 15330338231192902
DOI 10.1177/15330338231192902, PubMed 37574949

Thorgersen EB, Solbakken AM, Strøm TK, Goscinski M, Spasojevic M, Larsen SG, Flatmark K (2023)
Short-term results after robot-assisted surgery for primary rectal cancers requiring beyond total mesorectal excision in multiple compartments
Scand J Surg, 113 (1), 3-12
DOI 10.1177/14574969231200654, PubMed 37787437

Publications 2022

Cashin PH, Esquivel J, Larsen SG, Liauw W, Alzahrani NA, Morris DL, Kepenekian V, Sourrouille I, Dumont F, Tuech JJ, Ceribelli C, Doussot B, Sgarbura O, Quenet F, Glehen O, Fisher OM, Peritoneal Surface Oncology Group International (PSOGI), Nordic Peritoneal Oncology Group (NPOG), American Society for Peritoneal Surface Malignancy (ASPSM), BIG-RENAPE Groups (2022)
Perioperative chemotherapy in colorectal cancer with peritoneal metastases: A global propensity score matched study
EClinicalMedicine, 55, 101746
DOI 10.1016/j.eclinm.2022.101746, PubMed 36457647

Publications 2021

Larsen SG, Goscinski MA, Dueland S, Steigen SE, Hofsli E, Torgunrud A, Lund-Iversen M, Dagenborg VJ, Flatmark K, Sorbye H (2021)
Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
Br J Cancer, 126 (5), 726-735
DOI 10.1038/s41416-021-01620-6, PubMed 34887523

Mariathasan AB, Boye K, Dueland S, Flatmark K, Larsen SG (2021)
Metastases in locally advanced rectal cancer undergoing curatively intended treatment
Eur J Surg Oncol, 47 (9), 2377-2383
DOI 10.1016/j.ejso.2021.04.023, PubMed 34049768

Slørdahl KS, Klotz D, Olsen JÅ, Skovlund E, Undseth C, Abildgaard HL, Brændengen M, Nesbakken A, Larsen SG, Hanekamp BA, Holmboe L, Tvedt R, Sveen A, Lothe RA, Malinen E, Kaasa S, Guren MG (2021)
Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
Acta Oncol, 60 (7), 921-930
DOI 10.1080/0284186X.2021.1918763, PubMed 33966592

Spasojevic M, Mariathasan AB, Frich L, Bruland ØS, Larsen SG, Stoldt S (2021)
[Cancer therapy with isolated limb perfusion]
Tidsskr Nor Laegeforen, 141 (2021-12)
DOI 10.4045/tidsskr.21.0194, PubMed 34505491

Spasojevic M, Mariathasan AB, Frich L, Brulund OS, Larsen SG, Stoldt S (2021)
Cancer treatment with isolated extremity perfusion
Tidsskr. Nor. Laegeforen., 141 (12), 1186-1189

Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2021)
Correction to: Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of highgrade pseudomyxoma peritonei
Clin Exp Metastasis, 38 (2), 253
DOI 10.1007/s10585-021-10084-0, PubMed 33649933

Thorgersen EB, Asvall J, Frøysnes IS, Schjalm C, Larsen SG, Dueland S, Andersson Y, Fodstad Ø, Mollnes TE, Flatmark K (2021)
Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
Ann Surg Oncol, 28 (9), 5252-5262
DOI 10.1245/s10434-021-10022-0, PubMed 34019185

Publications 2020

Al-Haidari G, Skovlund E, Undseth C, Rekstad BL, Larsen SG, Åsli LM, Dueland S, Malinen E, Guren MG (2020)
Re-irradiation for recurrent rectal cancer - a single-center experience
Acta Oncol, 59 (5), 534-540
DOI 10.1080/0284186X.2020.1725111, PubMed 32056476

Larsen SG, Faerden AE, Wasmuth HH (2020)
Author response to: Comment on: Transanal total mesorectal excision for rectal cancer has been abandoned in Norway
Br J Surg, 107 (7), e222
DOI 10.1002/bjs.11592, PubMed 32364255

Wasmuth HH, Faerden AE, Larsen SG (2020)
Author response to: Comment on: Transanal total mesorectal excision for rectal cancer has been abandoned in Norway
Br J Surg, 107 (7), e224
DOI 10.1002/bjs.11596, PubMed 32364249

Wasmuth HH, Larsen SG, Faerden AE (2020)
TaTME and the worse oncological outcome - new data demonstrates a difficult method
Br J Surg, 107 (12), e611
DOI 10.1002/bjs.11850, PubMed 32936942

Publications 2019

Frøysnes IS, Andersson Y, Larsen SG, Davidson B, Øien JT, Julsrud L, Fodstad Ø, Dueland S, Flatmark K (2019)
ImmunoPeCa trial: Long-term outcome following intraperitoneal MOC31PE immunotoxin treatment in colorectal peritoneal metastasis
Eur J Surg Oncol, 47 (1), 134-138
DOI 10.1016/j.ejso.2019.04.014, PubMed 31036394

Larsen SG, Pfeffer F, Kørner H (2019)
Author response to: Comments on: Norwegian moratorium on transanal total mesorectal excision
Br J Surg, 106 (13), 1855
DOI 10.1002/bjs.11374, PubMed 31747073

Larsen SG, Pfeffer F, Kørner H, Norwegian Colorectal Cancer Group (2019)
Norwegian moratorium on transanal total mesorectal excision
Br J Surg, 106 (9), 1120-1121
DOI 10.1002/bjs.11287, PubMed 31304578

Lund-Andersen C, Nakken S, Nygård S, Fromm B, Aasheim LB, Davidson B, Julsrud L, Abrahamsen TW, Kristensen AT, Dybdahl B, Larsen SG, Hovig E, Flatmark K (2019)
Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response
Cold Spring Harb Mol Case Stud, 5 (2)
DOI 10.1101/mcs.a003566, PubMed 30862609

Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2019)
Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of high-grade pseudomyxoma peritonei
Clin Exp Metastasis, 36 (6), 511-518
DOI 10.1007/s10585-019-09991-0, PubMed 31541325

Wasmuth HH, Faerden AE, Myklebust TÅ, Pfeffer F, Norderval S, Riis R, Olsen OC, Lambrecht JR, Kørner H, Larsen SG, Norwegian TaTME Collaborative Group, on behalf of the Norwegian Colorectal Cancer Group, Forsmo HM, Baekkelund O, Lavik S, Knapp JC, Sjo O, Rashid G (2019)
Transanal total mesorectal excision for rectal cancer has been suspended in Norway
Br J Surg, 107 (1), 121-130
DOI 10.1002/bjs.11459, PubMed 31802481

Publications 2018

Mariathasan AB, Boye K, Giercksky KE, Brennhovd B, Gullestad HP, Emblemsvåg HL, Grøholt KK, Dueland S, Flatmark K, Larsen SG (2018)
Beyond total mesorectal excision in locally advanced rectal cancer with organ or pelvic side-wall involvement
Eur J Surg Oncol, 44 (8), 1226-1232
DOI 10.1016/j.ejso.2018.03.029, PubMed 29691115

Spasojevic M, Mariathasan AB, Goscinski M, Thorgersen EB, Solbakken AM, Gullestad HP, Ryder T, Flatmark K, Larsen SG (2018)
Vertical Rectus Abdominis Musculocutaneous Flap Repair Improves Perineal Wound Healing after Abdominoperineal Resection for Irradiated Locally Advanced Rectal Cancer
Ann Surg Oncol, 25 (5), 1357-1365
DOI 10.1245/s10434-018-6363-3, PubMed 29497909

Thorgersen EB, Melum E, Folseraas T, Larsen SG, Line PD (2018)
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: a case report
World J Surg Oncol, 16 (1), 180
DOI 10.1186/s12957-018-1482-7, PubMed 30185175

Publications 2017

Frøysnes IS, Andersson Y, Larsen SG, Davidson B, Øien JT, Olsen KH, Giercksky KE, Julsrud L, Fodstad Ø, Dueland S, Flatmark K (2017)
Novel Treatment with Intraperitoneal MOC31PE Immunotoxin in Colorectal Peritoneal Metastasis: Results From the ImmunoPeCa Phase 1 Trial
Ann Surg Oncol, 24 (7), 1916-1922
DOI 10.1245/s10434-017-5814-6, PubMed 28224367

Grut H, Solberg S, Seierstad T, Revheim ME, Egge TS, Larsen SG, Line PD, Dueland S (2017)
Growth rates of pulmonary metastases after liver transplantation for unresectable colorectal liver metastases
Br J Surg, 105 (3), 295-301
DOI 10.1002/bjs.10651, PubMed 29168565

Publications 2016

Dueland S, Ree AH, Grøholt KK, Saelen MG, Folkvord S, Hole KH, Seierstad T, Larsen SG, Giercksky KE, Wiig JN, Boye K, Flatmark K (2016)
Oxaliplatin-containing Preoperative Therapy in Locally Advanced Rectal Cancer: Local Response, Toxicity and Long-term Outcome
Clin Oncol (R Coll Radiol), 28 (8), 532-9
DOI 10.1016/j.clon.2016.01.014, PubMed 26888115

Frøysnes IS, Larsen SG, Spasojevic M, Dueland S, Flatmark K (2016)
Complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastasis in Norway: Prognostic factors and oncologic outcome in a national patient cohort
J Surg Oncol, 114 (2), 222-7
DOI 10.1002/jso.24290, PubMed 27173150

Thorgersen EB, Goscinski MA, Spasojevic M, Solbakken AM, Mariathasan AB, Boye K, Larsen SG, Flatmark K (2016)
Deep Pelvic Surgical Site Infection After Radiotherapy and Surgery for Locally Advanced Rectal Cancer
Ann Surg Oncol, 24 (3), 721-728
DOI 10.1245/s10434-016-5621-5, PubMed 27766561

Publications 2015

Goscinski MA, Larsen SG, Giercksky KE, Nesland JM, Suo Z (2015)
PDGFR-α and CD117 Expression Pattern in Esophageal Carcinomas
Anticancer Res, 35 (7), 3793-9
PubMed 26124324

Goscinski MA, Larsen SG, Giercksky KE, Nesland JM, Suo ZH (2015)
PDGFR-alpha and CD117 Expression Pattern in Esophageal Carcinomas
Anticancer Res., 35 (7), 3793-3799

Goscinski MA, Xu R, Zhou F, Wang J, Yang H, Huang R, Li Y, Larsen SG, Giercksky KE, Nesland JM, Suo Z (2015)
Nuclear, cytoplasmic, and stromal expression of ZEB1 in squamous and small cell carcinoma of the esophagus
APMIS, 123 (12), 1040-7
DOI 10.1111/apm.12473, PubMed 26547370

Guren MG, Kørner H, Pfeffer F, Myklebust TÅ, Eriksen MT, Edna TH, Larsen SG, Knudsen KO, Nesbakken A, Wasmuth HH, Vonen B, Hofsli E, Færden AE, Brændengen M, Dahl O, Steigen SE, Johansen MJ, Lindsetmo RO, Drolsum A, Tollåli G, Dørum LM, Møller B, Wibe A (2015)
Nationwide improvement of rectal cancer treatment outcomes in Norway, 1993-2010
Acta Oncol, 54 (10), 1714-22
DOI 10.3109/0284186X.2015.1034876, PubMed 25924970

Lambrecht JR, Larsen SG, Reiertsen O, Vaktskjold A, Julsrud L, Flatmark K (2015)
Prophylactic mesh at end-colostomy construction reduces parastomal hernia rate: a randomized trial
Colorectal Dis, 17 (10), O191-7
DOI 10.1111/codi.13065, PubMed 26179984

Publications 2014

Raabe NK, Sundfør K, Hole KH, Djupvik LH, Larsen SG, Dueland S (2014)
[High-dose-rate brachytherapy in recurrent rectal cancer after conventional recurrence treatment]
Tidsskr Nor Laegeforen, 134 (20), 1929-30
DOI 10.4045/tidsskr.14.1162, PubMed 25350435

Publications 2013

Hole KH, Larsen SG, Grøholt KK, Giercksky KE, Ree AH (2013)
Magnetic resonance-guided histopathology for improved accuracy of tumor response evaluation of neoadjuvant treatment in organ-infiltrating rectal cancer
Radiother Oncol, 107 (2), 178-83
DOI 10.1016/j.radonc.2013.03.017, PubMed 23602370

Larsen SG (2013)
Value of laparoscopy before cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis (Br J Surg 2013; 100: 285-292)
Br J Surg, 100 (2), 292
DOI 10.1002/bjs.8907, PubMed 23239481

Publications 2012

Cao C, Yan TD, Morris DL, van der Speeten K, Laurberg S, Glehen O, Link K, Piso P, Tentes AA, Deraco M, Larsen SG, Kecmanovic D, Bayón LG, Melero JT, González-Moreno S, Mahteme H, Gertsch P, Moran B, Esquivel J, Alexander R, Levine EA, Sugarbaker PH (2012)
Prospective Registry On Mesothelioma Peritonei Treatment (PROMPT): study design and rationale
Tumori, 98 (1), 166-71
DOI 10.1177/030089161209800124, PubMed 22495719

Sørensen O, Flatmark K, Reed W, Wiig JN, Dueland S, Giercksky KE, Larsen SG (2012)
Evaluation of complete cytoreductive surgery and two intraperitoneal chemotherapy techniques in Pseudomyxoma peritonei
Eur J Surg Oncol, 38 (10), 969-76
DOI 10.1016/j.ejso.2012.06.552, PubMed 22763244

Publications 2011

Wiig JN, Larsen SG, Dueland S, Flatmark K, Giercksky KE (2011)
Salvage surgery for locally recurrent rectal cancer: total mesorectal excision during the primary operation does not influence the outcome
Colorectal Dis, 13 (5), 506-11
DOI 10.1111/j.1463-1318.2010.02256.x, PubMed 20236148

Publications 2009

Goscinski MA, Larsen SG, Warloe T, Stoldt S, Nesland JM, Suo ZH, Giercksky KE (2009)
Adenocarcinomas on the rise--does it influence survival from oesophageal cancer?
Scand J Surg, 98 (4), 214-20
DOI 10.1177/145749690909800404, PubMed 20218417

Larsen SG (2009)
Locally advanced primary and recurrent rectal cancer: surgical experience after multimodality treatment at the Norwegian Radium Hospital
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 730, 1 b. (flere pag.)
BIBSYS 090176537, ISBN 978-82-8072-301-7

Publications 2008

Kristensen AT, Wiig JN, Larsen SG, Giercksky KE, Ekstrøm PO (2008)
Molecular detection (k-ras) of exfoliated tumour cells in the pelvis is a prognostic factor after resection of rectal cancer?
BMC Cancer, 8, 213
DOI 10.1186/1471-2407-8-213, PubMed 18655729

Larsen SG, Wiig JN, Emblemsvaag HL, Grøholt KK, Hole KH, Bentsen A, Dueland S, Vetrhus T, Giercksky KE (2008)
Extended total mesorectal excision in locally advanced rectal cancer (T4a) and the clinical role of MRI-evaluated neo-adjuvant downstaging
Colorectal Dis, 11 (7), 759-67
DOI 10.1111/j.1463-1318.2008.01649.x, PubMed 18662240

Publications 2007

Flatmark K, Reed W, Halvorsen T, Sørensen O, Wiig JN, Larsen SG, Fodstad Ø, Giercksky KE (2007)
Pseudomyxoma peritonei--two novel orthotopic mouse models portray the PMCA-I histopathologic subtype
BMC Cancer, 7, 116
DOI 10.1186/1471-2407-7-116, PubMed 17603904

Larsen SG, Wiig JN, Dueland S, Giercksky KE (2007)
Prognostic factors after preoperative irradiation and surgery for locally advanced rectal cancer
Eur J Surg Oncol, 34 (4), 410-7
DOI 10.1016/j.ejso.2007.05.012, PubMed 17614249

Wiig JN, Larsen SG, Dueland S, Giercksky KE (2007)
Preoperative irradiation and surgery for local recurrence of rectal and rectosigmoid cancer. Prognostic factors with regard to survival and further local recurrence
Colorectal Dis, 10 (1), 48-57
DOI 10.1111/j.1463-1318.2007.01398.x, PubMed 18028472

Publications 2006

Høiseth LØ, Giercksky KE, Larsen SG, Kongsgaard U (2006)
[Major surgery on Jehovah's Witnesses]
Tidsskr Nor Laegeforen, 126 (20), 2658-61
PubMed 17057765

Larsen SG, Wiig JN, Tretli S, Giercksky KE (2006)
Surgery and pre-operative irradiation for locally advanced or recurrent rectal cancer in patients over 75 years of age
Colorectal Dis, 8 (3), 177-85
DOI 10.1111/j.1463-1318.2005.00877.x, PubMed 16466556

Publications 2005

Larsen SG, Wiig JN, Giercksky KE (2005)
Hydronephrosis as a prognostic factor in pelvic recurrence from rectal and colon carcinomas
Am J Surg, 190 (1), 55-60
DOI 10.1016/j.amjsurg.2004.07.043, PubMed 15972173

Wiig JN, Larsen SG, Dueland S, Giercksky KE (2005)
Clinical outcome in patients with complete pathologic response (pT0) to preoperative irradiation/chemo-irradiation operated for locally advanced or locally recurrent rectal cancer
J Surg Oncol, 92 (1), 70-5
DOI 10.1002/jso.20340, PubMed 16180215

Wiig JN, Larsen SG, Giercksky KE (2005)
Operative treatment of locally recurrent rectal cancer
Recent Results Cancer Res, 165, 136-47
DOI 10.1007/3-540-27449-9_15, PubMed 15865028

Publications 2003

Wiig JN, Waehre H, Larsen SG, Braendengen M, Giercksky KE (2003)
Radical prostatectomy for locally advanced primary or recurrent rectal cancer
Eur J Surg Oncol, 29 (5), 455-8
DOI 10.1016/s0748-7983(03)00030-1, PubMed 12798751

Publications 2000

Calam RM, Jimmieson P, Cox AD, Glasgow DV, Larsen SG (2000)
Can computer-based assessment help us understand children's pain?
Eur J Anaesthesiol, 17 (5), 284-8
DOI 10.1046/j.1365-2346.2000.00655.x, PubMed 10926067

Publications 1999

Larsen SG, Nilssen A, Helseth A, Bøhler P, Giercksky KE (1999)
Invagination of the appendix with carcinoid tumour
Eur J Surg, 165 (10), 993-7
DOI 10.1080/110241599750008152, PubMed 10574110

Larsen SG, Wiiu JN, Giercksky KE, Berner A (1999)
[Transrectal specimens in recurrent rectal cancer]
Tidsskr Nor Laegeforen, 119 (28), 4170-2
PubMed 10668377

Publications 1973

Larsen SG, Hudson FG (1973)
Oral kinesthetic sensitivity and the perception of speech
Child Dev, 44 (4), 845-8
PubMed 4751306