Kristoffer Watten Brudvik
- MD, PhD
Publications 2024
Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy and Liver Resection is a Treatment Option for Patients With Peritoneal and Liver Metastases From Colorectal Cancer
Ann Surg, 280 (5), 745-52 (in press)
DOI 10.1097/SLA.0000000000006492, PubMed 39185557
Aggregated 1-year complication rates and health-related quality of life after reconstructive surgery for rectal cancer with or without diverting stoma (Norwegian Stoma Trial): a protocol for national multicentre, open-label, prospective cohort study
BJS Open, 8 (1)
DOI 10.1093/bjsopen/zrae010, PubMed 38386703
Publications 2023
Preoperative Inflammatory Markers in Liver Resection for Colorectal Liver Metastases: A National Registry-Based Study
World J Surg, 47 (9), 2213-2220
DOI 10.1007/s00268-023-07035-z, PubMed 37140610
Benchmarks and Geographic Differences in Gallbladder Cancer Surgery: An International Multicenter Study
Ann Surg Oncol, 30 (8), 4904-4911
DOI 10.1245/s10434-023-13531-2, PubMed 37149547
Publications 2022
Laparoscopic versus open liver resection for intrahepatic cholangiocarcinoma: a multicenter propensity score-matched study
Scand J Gastroenterol, 58 (5), 489-496
DOI 10.1080/00365521.2022.2143724, PubMed 36373379
Publications 2021
Genomic and prognostic heterogeneity among RAS/BRAFV600E /TP53 co-mutated resectable colorectal liver metastases
Mol Oncol, 15 (4), 830-845
DOI 10.1002/1878-0261.12885, PubMed 33325154
Survival Outcomes After Portal Vein Embolization and Liver Resection Compared With Liver Transplant for Patients With Extensive Colorectal Cancer Liver Metastases
JAMA Surg, 156 (6), 550-557
DOI 10.1001/jamasurg.2021.0267, PubMed 33787838
De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
Genome Med, 13 (1), 143
DOI 10.1186/s13073-021-00956-1, PubMed 34470666
Publications 2020
Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
Clin Cancer Res, 26 (15), 4107-4119
DOI 10.1158/1078-0432.CCR-19-3637, PubMed 32299813
Publications 2019
RAS Mutation Clinical Risk Score to Predict Survival After Resection of Colorectal Liver Metastases
Ann Surg, 269 (1), 120-126
DOI 10.1097/SLA.0000000000002319, PubMed 28549012
Limitations of molecular biomarkers in patients with resectable colorectal liver metastases
Chin Clin Oncol, 8 (5), 48
DOI 10.21037/cco.2019.08.02, PubMed 31500431
Survey of the attitudes of hepatopancreatobiliary surgeons in northern Europe to resection of choledochal cysts in asymptomatic Western adults
BJS Open, 3 (6), 785-792
DOI 10.1002/bjs5.50208, PubMed 31832585
Heterogeneous radiological response to neoadjuvant therapy is associated with poor prognosis after resection of colorectal liver metastases
Eur J Surg Oncol, 45 (12), 2340-2346
DOI 10.1016/j.ejso.2019.07.017, PubMed 31350075
High Concordance and Negative Prognostic Impact of RAS/BRAF/PIK3CA Mutations in Multiple Resected Colorectal Liver Metastases
Clin Colorectal Cancer, 19 (1), e26-e47
DOI 10.1016/j.clcc.2019.09.003, PubMed 31982351
Treatment Options for Metastatic Gastrointestinal Stromal Tumors to the Liver: A Review
Semin Liver Dis, 39 (3), 395-402
DOI 10.1055/s-0039-1685517, PubMed 31100757
Characterization of early recurrences following liver resection by ALPPS and two stage hepatectomy in patients with colorectal liver-metastases and small future liver remnants; a translational substudy of the LIGRO-RCT
HPB (Oxford), 21 (8), 1017-1023
DOI 10.1016/j.hpb.2018.12.003, PubMed 30765198
Preoperative detection of colorectal liver metastases: DWI alone or combined with MDCT is no substitute for Gd-EOB-DTPA-enhanced MRI
Acta Radiol, 61 (3), 302-311
DOI 10.1177/0284185119864000, PubMed 31335157
Publications 2018
Survival after resection of colorectal liver metastases in octogenarians and sexagenarians compared to their respective age-matched national population
Hepatobiliary Surg Nutr, 7 (4), 234-241
DOI 10.21037/hbsn.2017.09.03, PubMed 30221151
Association between the lymph node ratio and hepatic tumor burden: importance for resectable colorectal liver metastases?
Hepatobiliary Surg Nutr, 7 (3), 206-208
DOI 10.21037/hbsn.2018.03.02, PubMed 30046575
Risk for hemorrhage after pancreatoduodenectomy with venous resection
Langenbecks Arch Surg, 403 (8), 949-957
DOI 10.1007/s00423-018-1721-y, PubMed 30397778
Contemporary practice and short-term outcomes after liver resections in a complete national cohort
Langenbecks Arch Surg, 404 (1), 11-19
DOI 10.1007/s00423-018-1737-3, PubMed 30519886
Embryonic Origin of Primary Colon Cancer Predicts Pathologic Response and Survival in Patients Undergoing Resection for Colon Cancer Liver Metastases
Ann Surg, 267 (3), 514-520
DOI 10.1097/SLA.0000000000002087, PubMed 28002060
Publications 2017
Unplanned readmission and outpatient examination 90-days after acute appendectomy in adults
Am J Surg, 216 (2), 217-221
DOI 10.1016/j.amjsurg.2017.07.020, PubMed 28760356
Surgery: KRAS mutations and hepatic recurrence after treatment of colorectal liver metastases
Nat Rev Gastroenterol Hepatol, 14 (11), 638-639
DOI 10.1038/nrgastro.2017.129, PubMed 28930294
Precision surgery for colorectal liver metastases: Opportunities and challenges of omics-based decision making
Eur J Surg Oncol, 43 (5), 875-883
DOI 10.1016/j.ejso.2017.02.014, PubMed 28302330
Follow-up After Surgery for Pancreatic Ductal Adenocarcinoma: Steps Toward an International Consensus
Pancreas, 46 (1), e2-e3
DOI 10.1097/MPA.0000000000000689, PubMed 27977631
Resection of synchronous liver metastases between radiotherapy and definitive surgery for locally advanced rectal cancer: short-term surgical outcomes, overall survival and recurrence-free survival
Colorectal Dis, 19 (8), 731-738
DOI 10.1111/codi.13622, PubMed 28181384
Factors associated with hernia recurrence after laparoscopic total extraperitoneal repair for inguinal hernia: a 2-year prospective cohort study
Hernia, 21 (5), 729-735
DOI 10.1007/s10029-017-1634-7, PubMed 28752424
Survival Impact of Primary Tumor Lymph Node Status and Circulating Tumor Cells in Patients with Colorectal Liver Metastases
Ann Surg Oncol, 24 (8), 2113-2121
DOI 10.1245/s10434-017-5818-2, PubMed 28258416
Publications 2016
Aspirin As Secondary Prevention in Patients With Colorectal Cancer: An Unselected Population-Based Study
J Clin Oncol, 34 (21), 2501-8
DOI 10.1200/JCO.2015.65.3519, PubMed 27247217
Reply to M. Løberg et al
J Clin Oncol, 35 (5), 569-571
DOI 10.1200/JCO.2016.70.8263, PubMed 29236616
Validation of clinical risk scores for laparoscopic liver resections of colorectal liver metastases: A 10-year observed follow-up study
J Surg Oncol, 114 (6), 757-763
DOI 10.1002/jso.24391, PubMed 27471127
RAS Mutation Predicts Positive Resection Margins and Narrower Resection Margins in Patients Undergoing Resection of Colorectal Liver Metastases
Ann Surg Oncol, 23 (8), 2635-43
DOI 10.1245/s10434-016-5187-2, PubMed 27016292
Colorectal Liver Metastases: A Changing Treatment Landscape
J Oncol Pract, 12 (1), 40-1
DOI 10.1200/JOP.2015.009746, PubMed 26759465
Re "Comparison of techniques for volumetric analysis of the future liver remnant: implications for major hepatic resections"
HPB (Oxford), 18 (6), 557
DOI 10.1016/j.hpb.2016.02.008, PubMed 27317961
RAS Mutation Is Associated with Decreased Survival in Patients Undergoing Repeat Hepatectomy for Colorectal Liver Metastases
J Gastrointest Surg, 21 (1), 68-77
DOI 10.1007/s11605-016-3189-9, PubMed 27334313
Parenchymal-sparing Hepatectomy in Colorectal Liver Metastasis Improves Salvageability and Survival
Ann Surg, 263 (1), 146-52
DOI 10.1097/SLA.0000000000001194, PubMed 25775068
After Pancreatectomy, the “90 Days from Surgery” Definition Is Superior to the “30 Days from Discharge” Definition for Capture of Clinically Relevant Readmissions
J Gastrointest Surg, 20 (1), 77-84; discussion 84
DOI 10.1007/s11605-015-2984-z, PubMed 26493976
A Nomogram to Predict Hypertrophy of Liver Segments 2 and 3 After Right Portal Vein Embolization
J Gastrointest Surg, 20 (7), 1317-23
DOI 10.1007/s11605-016-3145-8, PubMed 27073080
Predictors of Safety and Efficacy of 2-Stage Hepatectomy for Bilateral Colorectal Liver Metastases
J Am Coll Surg, 223 (1), 99-108
DOI 10.1016/j.jamcollsurg.2015.12.057, PubMed 26968325
Is hepatectomy justified for patients with RAS mutant colorectal liver metastases? An analysis of 524 patients undergoing curative liver resection
Surgery, 161 (2), 332-340
DOI 10.1016/j.surg.2016.07.032, PubMed 27592215
Is Extended Lymphadenectomy Needed for Elderly Patients With Gastric Adenocarcinoma?
Ann Surg Oncol, 23 (8), 2391-7
DOI 10.1245/s10434-016-5260-x, PubMed 27169773
Publications 2015
Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastases
Br J Surg, 102 (10), 1175-83
DOI 10.1002/bjs.9870, PubMed 26206254
Definition of Readmission in 3,041 Patients Undergoing Hepatectomy
J Am Coll Surg, 221 (1), 38-46
DOI 10.1016/j.jamcollsurg.2015.01.063, PubMed 26047760
Survival After Resection of Gastrointestinal Stromal Tumor and Sarcoma Liver Metastases in 146 Patients
J Gastrointest Surg, 19 (8), 1476-83
DOI 10.1007/s11605-015-2845-9, PubMed 26001368
Detection of Circulating Tumor Cells at Surgery and at Follow-Up Assessment to Predict Survival After Two-Stage Liver Resection of Colorectal Liver Metastases
Ann Surg Oncol, 22 (12), 4029-37
DOI 10.1245/s10434-015-4482-7, PubMed 25801354
Peeling-off technique or bile duct resection of tumor thrombus in hepatocellular carcinoma: does future liver-directed treatment justify less extensive surgery?
Ann Surg, 261 (5), e126
DOI 10.1097/SLA.0000000000001210, PubMed 25775077
Advances in hepatectomy technique: Toward zero transfusions in the modern era of liver surgery
Surgery, 159 (3), 793-801
DOI 10.1016/j.surg.2015.10.006, PubMed 26584854
Circulating tumor cells in patients with colorectal liver metastasis predict impaired survival
Ann Surg, 261 (1), 164-71
DOI 10.1097/SLA.0000000000000580, PubMed 24509211
Publications 2014
Is complete liver resection without resection of synchronous lung metastases justified?
Ann Surg Oncol, 22 (5), 1585-92
DOI 10.1245/s10434-014-4207-3, PubMed 25373535
Publications 2013
Aggressive treatment of patients with metastatic colorectal cancer increases survival: a scandinavian single-center experience
HPB Surg, 2013, 727095
DOI 10.1155/2013/727095, PubMed 23840074
Publications 2012
Modulation of T cell immune functions by the prostaglandin E(2) - cAMP pathway in chronic inflammatory states
Br J Pharmacol, 166 (2), 411-9
DOI 10.1111/j.1476-5381.2011.01800.x, PubMed 22141738
Kinetics and activation requirements of contact-dependent immune suppression by human regulatory T cells
J Immunol, 188 (11), 5459-66
DOI 10.4049/jimmunol.1101367, PubMed 22539784
Publications 2011
Regulatory T-cell-mediated inhibition of antitumor immune responses is associated with clinical outcome in patients with liver metastasis from colorectal cancer
Cancer Immunol Immunother, 61 (7), 1045-53
DOI 10.1007/s00262-011-1174-4, PubMed 22159472
Protein kinase A antagonist inhibits β-catenin nuclear translocation, c-Myc and COX-2 expression and tumor promotion in Apc(Min/+) mice
Mol Cancer, 10, 149
DOI 10.1186/1476-4598-10-149, PubMed 22168384