Publications 2021

Berg KCG, Brunsell TH, Sveen A, Alagaratnam S, Bjornslett M, Hektoen M, Brudvik KW, Rosok BI, Bjornbeth BA, Nesbakken A, Lothe RA (2021)
Genomic and prognostic heterogeneity among RAS/BRAF(V600E)/TP53 co-mutated resectable colorectal liver metastases
Mol. Oncol., 15 (4), 830-845
DOI 10.1002/1878-0261.12885

Dueland S, Yaqub S, Syversveen T, Carling U, Hagness M, Brudvik KW, Line PD (2021)
Survival Outcomes After Portal Vein Embolization and Liver Resection Compared With Liver Transplant for Patients With Extensive Colorectal Cancer Liver Metastases
JAMA Surg., 156 (6), 550-557
DOI 10.1001/jamasurg.2021.0267

Moosavi SH, Eide PW, Eilertsen IA, Brunsell TH, Berg KCG, Rosok BI, Brudvik KW, Bjornbeth BA, Guren MG, Nesbakken A, Lothe RA, Sveen A (2021)
De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
Genome Med., 13 (1), 143
DOI 10.1186/s13073-021-00956-1

Publications 2020

Brunsell TH, Sveen A, Bjornbeth BA, Rosok BI, Danielsen SA, Brudvik KW, Berg KCG, Johannessen B, Cengija V, Abildgaard A, Guren MG, Nesbakken A, Lothe RA (2020)
High Concordance and Negative Prognostic Impact of RAS/BRAF/PIK3CA Mutations in Multiple Resected Colorectal Liver Metastases
Clin. Colorectal Canc., 19 (1), E26-E47
DOI 10.1016/j.clcc.2019.09.003

Bruun J, Kryeziu K, Eide PW, Moosavi SH, Eilertsen IA, Langerud J, Rosok B, Totland MZ, Brunsell TH, Pellinen T, Saarela J, Bergsland CH, Palmer HG, Brudvik KW, Guren T, Dienstmann R, Guren MG, Nesbakken A, Bjornbeth BA, Sveen A, Lothe RA (2020)
Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
Clin. Cancer Res., 26 (15), 4107-4119
DOI 10.1158/1078-0432.CCR-19-3637

Schulz A, Joelsen-Hatlehol ES, Brudvik KW, Aasand KK, Hanekamp B, Viktil E, Johansen CK, Dormagen JB (2020)
Preoperative detection of colorectal liver metastases: DWI alone or combined with MDCT is no substitute for Gd-EOB-DTPA-enhanced MRI
Acta Radiol., 61 (3), 0284185119864000-311
DOI 10.1177/0284185119864000

Publications 2019

Brudvik KW, Jones RP, Giuliante F, Shindoh J, Passot G, Chung MH, Song J, Li L, Dagenborg VJ, Fretland AA, Rosok B, De Rose AM, Ardito F, Edwin B, Panettieri E, Larocca LM, Yamashita S, Conrad C, Aloia TA, Poston GJ, Bjornbeth BA, Vauthey JN (2019)
RAS Mutation Clinical Risk Score to Predict Survival After Resection of Colorectal Liver Metastases
Ann. Surg., 269 (1), 120-126
DOI 10.1097/SLA.0000000000002319

Brudvik KW, Shindoh J (2019)
Limitations of molecular biomarkers in patients with resectable colorectal liver metastases
Chin. Clin. Oncol., 8 (5), 48
DOI 10.21037/cco.2019.08.02

Brudvik KW, Yaqub S, Kemsley E, Coolsen MME, Dejong CHC, Wigmore SJ, Lassen K (2019)
Survey of the attitudes of hepatopancreatobiliary surgeons in northern Europe to resection of choledochal cysts in asymptomatic Western adults
BJS Open, 3 (6), 785-792
DOI 10.1002/bjs5.50208

Brunsell TH, Cengija V, Sveen A, Bjornbeth BA, Rosok BI, Brudvik KW, Guren MG, Lothe RA, Abildgaard A, Nesbakken A (2019)
Heterogeneous radiological response to neoadjuvant therapy is associated with poor prognosis after resection of colorectal liver metastases
EJSO, 45 (12), 2340-2346
DOI 10.1016/j.ejso.2019.07.017

Lassen K, Nymo LS, Olsen F, Brudvik KW, Fretland AA, Soreide K (2019)
Contemporary practice and short-term outcomes after liver resections in a complete national cohort
Langenbecks Arch. Surg., 404 (1), 11-19
DOI 10.1007/s00423-018-1737-3

Lillemoe HA, Brudvik KW, Vauthey JN (2019)
Treatment Options for Metastatic Gastrointestinal Stromal Tumors to the Liver: A Review
Semin. Liver Dis., 39 (3), 395-401
DOI 10.1055/s-0039-1685517

Rosok BI, Host-Brunsell T, Brudvik KW, Carling U, Dorenberg E, Bjornsson B, Lothe RA, Bjombeth BA, Sandstrom P (2019)
Characterization of early recurrences following liver resection by ALPPS and two stage hepatectomy in patients with colorectal liver-metastases and small future liver remnants; a translational substudy of the LIGRO-RCT
HPB, 21 (8), 1017-1023
DOI 10.1016/j.hpb.2018.12.003

Publications 2018

Bendvold B, Refsum A, Schjoth-Iversen L, Bringedal K, Husby A, Brudvik KW (2018)
Unplanned readmission and outpatient examination 90-days after acute appendectomy in adults
Am. J. Surg., 216 (2), 217-221
DOI 10.1016/j.amjsurg.2017.07.020

Brudvik KW, Rosok B, Naresh U, Yaqub S, Fretland AA, Labori KJ, Edwin B, Bjornbeth BA (2018)
Survival after resection of colorectal liver metastases in octogenarians and sexagenarians compared to their respective age-matched national population
Hepatobil. Surg. Nutr., 7 (4), 234-241
DOI 10.21037/hbsn.2017.09.03

Brudvik KW, Soreide K (2018)
Association between the lymph node ratio and hepatic tumor burden: importance for resectable colorectal liver metastases?
Hepatobil. Surg. Nutr., 7 (3), 206-208
DOI 10.21037/hbsn.2018.03.02

Kleive D, Sahakyan M, Soreide K, Brudvik KW, Line PD, Gladhaug IP, Labori KJ (2018)
Risk for hemorrhage after pancreatoduodenectomy with venous resection
Langenbecks Arch. Surg., 403 (8), 949-957
DOI 10.1007/s00423-018-1721-y

Publications 2017

Brudvik KW, Vauthey JN (2017)
SURGERY KRAS mutations and hepatic recurrence after treatment of colorectal liver metastases
Nat. Rev. Gastroenterol. Hepatol., 14 (11), 638-639
DOI 10.1038/nrgastro.2017.129

Jones RP, Brudvik KW, Franklin JM, Poston GJ (2017)
Precision surgery for colorectal liver metastases: Opportunities and challenges of omics-based decision making
EJSO, 43 (5), 875-883
DOI 10.1016/j.ejso.2017.02.014

Labori KJ, Brudvik KW (2017)
Follow-up After Surgery for Pancreatic Ductal Adenocarcinoma Steps Toward an International Consensus
Pancreas, 46 (1), E2-E3
DOI 10.1097/MPA.0000000000000689

Labori KJ, Guren MG, Brudvik KW, Rosok BI, Waage A, Nesbakken A, Larsen S, Dueland S, Edwin B, Bjornbeth BA (2017)
Resection of synchronous liver metastases between radiotherapy and definitive surgery for locally advanced rectal cancer: short-term surgical outcomes, overall survival and recurrence-free survival
Colorectal Dis., 19 (8), 731-738
DOI 10.1111/codi.13622

Mahic M, Myklebust TA, Smastuen MC, Yaqub S, Dorum LM, Bjornbeth BA, Moller B, Brudvik KW, Tasken K (2017)
Aspirin, Colorectal Cancer, and Cause of Death: A Complex Landscape Reply
J. Clin. Oncol., 35 (5), 569-+
DOI 10.1200/JCO.2016.70.8263

Schjoth-Iversen L, Refsum A, Brudvik KW (2017)
Factors associated with hernia recurrence after laparoscopic total extraperitoneal repair for inguinal hernia: a 2-year prospective cohort study
Hernia, 21 (5), 729-735
DOI 10.1007/s10029-017-1634-7

Seeberg LT, Brunborg C, Waage A, Hugenschmidt H, Renolen A, Stav I, Bjornbeth BA, Borgen E, Naume B, Brudvik KW, Wiedswang G (2017)
Survival Impact of Primary Tumor Lymph Node Status and Circulating Tumor Cells in Patients with Colorectal Liver Metastases
Ann. Surg. Oncol., 24 (8), 2113-2121
DOI 10.1245/s10434-017-5818-2

Publications 2016

Bains SJ, Mahic M, Myklebust TA, Smastuen MC, Yaqub S, Dorum LM, Bjornbeth BA, Moller B, Brudvik KW, Tasken K (2016)
Aspirin As Secondary Prevention in Patients With Colorectal Cancer: An Unselected Population-Based Study
J. Clin. Oncol., 34 (21), 2501-+
DOI 10.1200/JCO.2015.65.3519

Barkhatov L, Fretland AA, Kazaryan AM, Rosok BI, Brudvik KW, Waage A, Bjornbeth BA, Sahakyan MA, Edwin B (2016)
Validation of Clinical Risk Scores for Laparoscopic Liver Resections of Colorectal Liver Metastases: A 10-Year Observed Follow-Up Study
J. Surg. Oncol., 114 (6), 757-763
DOI 10.1002/jso.24391

Brudvik KW, Vauthey JN (2016)
Re "Comparison of techniques for volumetric analysis of the future liver remnant: implications for major hepatic resections"
HPB, 18 (6), 557
DOI 10.1016/j.hpb.2016.02.008

Passot G, Vaudoyer D, Messager M, Brudvik KW, Kim BJ, Mariette C, Glehen O (2016)
Is Extended Lymphadenectomy Needed for Elderly Patients With Gastric Adenocarcinoma?
Ann. Surg. Oncol., 23 (8), 2391-2397
DOI 10.1245/s10434-016-5260-x

Publications 2015

Brudvik KW, Seeberg LT, Hugenschmidt H, Renolen A, Schirmer CB, Brunborg C, Bjornbeth BA, Borgen E, Naume B, Waage A, Wiedswang G (2015)
Detection of Circulating Tumor Cells at Surgery and at Follow-Up Assessment to Predict Survival After Two-Stage Liver Resection of Colorectal Liver Metastases
Ann. Surg. Oncol., 22 (12), 4029-4037
DOI 10.1245/s10434-015-4482-7

Seeberg LT, Waage A, Brunborg C, Hugenschmidt H, Renolen A, Stav I, Bjornbeth BA, Brudvik KW, Borgen EF, Naume B, Wiedswang G (2015)
Circulating Tumor Cells in Patients With Colorectal Liver Metastasis Predict Impaired Survival
Ann. Surg., 261 (1), 164-171
DOI 10.1097/SLA.0000000000000580

Publications 2012

Brudvik KW, Henjum K, Aandahl EM, Bjornbeth BA, Tasken K (2012)
Regulatory T-cell-mediated inhibition of antitumor immune responses is associated with clinical outcome in patients with liver metastasis from colorectal cancer
Cancer Immunol. Immunother., 61 (7), 1045-1053
DOI 10.1007/s00262-011-1174-4

Brudvik KW, Tasken K (2012)
Modulation of T cell immune functions by the prostaglandin E2-cAMP pathway in chronic inflammatory states
Br. J. Pharmacol., 166 (2), 411-419
DOI 10.1111/j.1476-5381.2011.01800.x

Hagness M, Henjum K, Landskron J, Brudvik KW, Bjornbeth BA, Foss A, Tasken K, Aandahl EM (2012)
Kinetics and Activation Requirements of Contact-Dependent Immune Suppression by Human Regulatory T Cells
J. Immunol., 188 (11), 5459-5466
DOI 10.4049/jimmunol.1101367

Publications 2011

Brudvik KW, Paulsen JE, Aandahl EM, Roald B, Tasken K (2011)
Protein kinase A antagonist inhibits beta-catenin nuclear translocation, c-Myc and COX-2 expression and tumor promotion in Apc(Min/+) mice
Mol. Cancer, 10, 149
DOI 10.1186/1476-4598-10-149