Publications 2025

Abu Hilal M, Hoogteijling TJ, Edwin B, Dagher I, D'Hondt M, Marques HP, Swijnenburg RJ, Boggi U, Sucandy I, Ferrero A, Marsman H, Troisi RI, Gumbs AA, Aldrighetti LA, Cherqui D, Alseidi A, Croner R, Rotellar F, Scatton O, Al Saati H, Berardi G, Cillo U, Cipriani F, Ciria R, Cugat E et al. (2025)
The Brescia internationally validated European guidelines on minimally invasive liver surgery
Br J Surg, 112 (6)
DOI 10.1093/bjs/znaf113, PubMed 40568914

Høye E, Kanduri C, Torgunrud A, Lorenz S, Edwin B, Larsen SG, Fretland ÅA, Dagenborg VJ, Flatmark K, Lund-Andersen C (2025)
Enrichment of Cancer-Associated Fibroblasts, Macrophages, and Up-Regulated TNF-α Signaling in the Tumor Microenvironment of CMS4 Colorectal Peritoneal Metastasis
Cancer Med, 14 (1), e70521
DOI 10.1002/cam4.70521, PubMed 39739693

Korenblik R, James S, Smits J, Díaz-Nieto R, Davis R, Chan BKY, Erdmann JI, Zijlstra IAJ, Arntz PJW, Kollmar O, Hoffmann MH, Vass DG, Lindsay R, Serenari M, Cappelli A, Gobardhan PD, Imani F, Suarez YF, Muños FG, Grünhagen DJ, Moelker A, Pieterman KJ, Kleeff J, Wohlgemuth WA, Herrero E et al. (2025)
Safety and efficacy of combined portal and hepatic vein embolisation in patients with colorectal liver metastases (DRAGON1): a multicentre, single-arm clinical trial
Lancet Reg Health Eur, 53, 101284
DOI 10.1016/j.lanepe.2025.101284, PubMed 40255933

Olij B, Fichtinger RS, Aldrighetti LA, Abu Hilal M, Troisi RI, Sutcliffe RP, Besselink MG, Aroori S, Menon KV, Edwin B, D'Hondt M, Lucidi V, Ulmer TF, Díaz-Nieto R, Soonawalla Z, White S, Sergeant G, Ratti F, Kuemmerli C, Scuderi V, Berrevoet F, Vanlander A, Marudanayagam R, Tanis PJ, Dewulf MJL et al. (2025)
Health-related quality of life in patients undergoing laparoscopic versus open hemihepatectomy: a secondary analysis of the ORANGE II PLUS randomised controlled, phase 3, superiority trial
Lancet Reg Health Eur, 54, 101311
DOI 10.1016/j.lanepe.2025.101311, PubMed 40491830

Perri G, Di Martino M, Minter R, Srinivasa S, Newhook T, Roch A, Guest R, Fretland A, Prodehl L, Thepbunchonchai A, Hallet J (2025)
Challenges in early career for HPB surgeons: an international practice survey
HPB (Oxford), 27 (6), 771-779
DOI 10.1016/j.hpb.2025.02.010, PubMed 40024851

Røsok BI, Ahmad SH, Fretland ÅA, Østergaard D, Edwin B, Brudvik KW, Yaqub S (2025)
Surgical resection of adrenal metastases: Single-center experience and narrative literature review with emphasis on colorectal metastases
Scand J Surg, 14574969251331341 (in press)
DOI 10.1177/14574969251331341, PubMed 40186550

Treider MA, Romandini E, Alavi DT, Aghayan D, Rasmussen MK, Marchegiani G, Lauritzen PM, Pelanis E, Edwin B, Blomhoff R, Fretland ÅA (2025)
Postoperative changes in body composition after laparoscopic and open resection of colorectal liver metastases: data from the randomized OSLO-COMET trial
Surg Endosc, 39 (4), 2450-2457
DOI 10.1007/s00464-025-11613-8, PubMed 39994051

Yaqub S, Longva A, Angelsen JH, Brudvik KW, Carling U, Edwin B, Fretland ÅA, Grünhagen DJ, Line PD, Røsok BI, Smedman TM, Sparrelid E, Syversveen T, Villanger O, Lassen K (2025)
Multimodal treatment for colorectal liver metastases: A toolbox for clinicians
Scand J Surg, 14574969251333524 (in press)
DOI 10.1177/14574969251333524, PubMed 40247715

Publications 2024

Bereska JI, Zeeuw M, Wagenaar L, Jenssen HB, Wesdorp NJ, van der Meulen D, Bereska LF, Gavves E, Janssen BV, Besselink MG, Marquering HA, van Waesberghe JTM, Aghayan DL, Pelanis E, van den Bergh J, Nota IIM, Moos S, Kemmerich G, Syversveen T, Kolrud FK, Huiskens J, Swijnenburg RJ, Punt CJA, Stoker J, Edwin B et al. (2024)
Development and external evaluation of a self-learning auto-segmentation model for Colorectal Cancer Liver Metastases Assessment (COALA)
Insights Imaging, 15 (1), 279
DOI 10.1186/s13244-024-01820-7, PubMed 39576456

Boretto L, Pelanis E, Regensburger A, Fretland ÅA, Edwin B, Elle OJ (2024)
Hybrid optical-vision tracking in laparoscopy: accuracy of navigation and ultrasound reconstruction
Minim Invasive Ther Allied Technol, 33 (3), 176-183
DOI 10.1080/13645706.2024.2313032, PubMed 38334755

Boretto L, Pelanis E, Regensburger A, Petkov K, Palomar R, Fretland ÅA, Edwin B, Elle OJ (2024)
Intraoperative patient-specific volumetric reconstruction and 3D visualization for laparoscopic liver surgery
Healthc Technol Lett, 11 (6), 374-383
DOI 10.1049/htl2.12106, PubMed 39720761

Carling U, Berger S, Gjønnæss E, Røsok B, Yaqub S, Lassen K, Fretland ÅA, Dorenberg E (2024)
Transfemoral hepatic vein access in double vein embolization - initial experience and feasibility
CVIR Endovasc, 7 (1), 64
DOI 10.1186/s42155-024-00478-y, PubMed 39225967

Fichtinger RS, Aldrighetti LA, Abu Hilal M, Troisi RI, Sutcliffe RP, Besselink MG, Aroori S, Menon KV, Edwin B, D'Hondt M, Lucidi V, Ulmer TF, Díaz-Nieto R, Soonawalla Z, White S, Sergeant G, Olij B, Ratti F, Kuemmerli C, Scuderi V, Berrevoet F, Vanlander A, Marudanayagam R, Tanis P, Dewulf MJL et al. (2024)
Laparoscopic Versus Open Hemihepatectomy: The ORANGE II PLUS Multicenter Randomized Controlled Trial
J Clin Oncol, 42 (15), 1799-1809
DOI 10.1200/JCO.23.01019, PubMed 38640453

Görgec B, Sijberden JP, Swijnenburg RJ, Fretland ÅA, Verhoef C, Besselink MG, Stoker J (2024)
Optimal imaging before local therapy of colorectal liver metastases - Authors' reply
Lancet Oncol, 25 (3), e101
DOI 10.1016/S1470-2045(24)00093-7, PubMed 38423054

Kuemmerli C, Sijberden JP, Cipriani F, Osei-Bordom D, Aghayan D, Lanari J, de Meyere C, Cacciaguerra AB, Rotellar F, Fuks D, Liu R, Besselink MG, Zimmitti G, Ruzzenente A, di Benedetto F, Succandy I, Efanov M, Memeo R, Jovine E, Vrochides D, Dagher I, Croner R, Lopez-Ben S, Geller D, Ahmad J et al. (2024)
Is prolonged operative time associated with postoperative complications in liver surgery? An international multicentre cohort study of 5424 patients
Surg Endosc, 38 (12), 7118-7130
DOI 10.1007/s00464-024-11276-x, PubMed 39347957

Kuiper BI, Abu Hilal M, Aldrighetti LA, Björnsson B, D'Hondt M, Dopazo C, Fretland ÅA, Isoniemi H, Philip Jonas J, Kazemier G, Lesurtel M, Primrose J, Schnitzbauer AA, Buffart T, Gruenberger B, Swijnenburg RJ, Gruenberger T (2024)
Pan-European survey on current treatment strategies in patients with upfront resectable colorectal liver metastases
HPB (Oxford), 26 (5), 639-647
DOI 10.1016/j.hpb.2024.01.007, PubMed 38373870

Mahootiha M, Qadir HA, Aghayan D, Fretland ÅA, von Gohren Edwin B, Balasingham I (2024)
Deep learning-assisted survival prognosis in renal cancer: A CT scan-based personalized approach
Heliyon, 10 (2), e24374
DOI 10.1016/j.heliyon.2024.e24374, PubMed 38298725

Nainamalai V, Qair HA, Pelanis E, Jenssen HB, Fretland ÅA, Edwin B, Elle OJ, Balasingham I (2024)
Automated algorithm for medical data structuring, and segmentation using artificial intelligence within secured environment for dataset creation
Eur J Radiol Open, 13, 100582
DOI 10.1016/j.ejro.2024.100582, PubMed 39041057

Pereira PL, Bale R, Fretland ÅA, Goldberg SN, Helmberger T, Meijerink MR, Orsi F, Stättner S, Vogl T, Kafkoula A, de Jong N, Zeka B, de Baère T (2024)
Correction to: Local Tumour Control Following Microwave Ablation: Protocol for the Prospective Observational CIEMAR Study
Cardiovasc Intervent Radiol, 47 (1), 130-131
DOI 10.1007/s00270-023-03618-4, PubMed 38010508

Perri G, Romandini E, Marchegiani G, Ghorbani P, Sahakyan M, Holmberg M, Cattelani A, Fretland Å, Montorsi R, Rodrigues ID, Kleive D, Bannone E, Edwin B, Gilg S, Labori K, Sparrelid E, Salvia R (2024)
Postoperative Hyperamylasemia (POH) is an Early Predictor of Pancreatic Fistula Occurrence and Severity after Distal Pancreatectomy: Results from a European Multicentric Study
Ann Surg (in press)
DOI 10.1097/SLA.0000000000006222, PubMed 38305035

Prasad PJR, Fretland AA, Albregtsen F, Elle OJ, Kumar RP (2024)
Transfer Learning with Interpretability: Liver Segmentation in CT and MR using Limited Dataset
Annu Int Conf IEEE Eng Med Biol Soc, 2024, 1-5
DOI 10.1109/EMBC53108.2024.10782042, PubMed 40039644

Ree AH, Høye E, Esbensen Y, Beitnes AR, Negård A, Bernklev L, Tetlie LK, Fretland ÅA, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Nilsen HL, Flatmark K, Meltzer S (2024)
Complete response of metastatic microsatellite-stable BRAF V600E colorectal cancer to first-line oxaliplatin-based chemotherapy and immune checkpoint blockade
Oncoimmunology, 13 (1), 2372886
DOI 10.1080/2162402X.2024.2372886, PubMed 38952672

Sijberden JP, Fiorentini G, Lanari J, Aghayan D, Osei-Bordom D, Russolillo N, Takhar A, Benedetti Cacciaguerra A, Lopez-Ben S, D'Hondt M, Giuliante F, Fuks D, Rotellar F, Ruzzenente A, Alseidi A, Efanov M, Görgec B, Zimmitti G, Gringeri E, Cipriani F, Fretland ÅA, Marudanayagam R, Vivarelli M, Primrose JN, Ferrero A et al. (2024)
The differential benefit of laparoscopic over open minor liver resection for lesions situated in the anterolateral or posterosuperior segments
Hepatobiliary Surg Nutr, 13 (4), 604-615
DOI 10.21037/hbsn-23-494, PubMed 39175716

Sijberden JP, Hoogteijling TJ, Aghayan D, Ratti F, Tan EK, Morrison-Jones V, Lanari J, Haentjens L, Wei K, Tzedakis S, Martinie J, Osei Bordom D, Zimmitti G, Crespo K, Magistri P, Russolillo N, Conci S, Görgec B, Benedetti Cacciaguerra A, D'Souza D, Zozaya G, Caula C, Geller D, Robles Campos R, Croner R et al. (2024)
Robotic Versus Laparoscopic Liver Resection in Various Settings: An International Multicenter Propensity Score Matched Study of 10.075 Patients
Ann Surg, 280 (1), 108-117
DOI 10.1097/SLA.0000000000006267, PubMed 38482665

Trehub Y, Fretland ÅA, Zelinskyi A, Kharkov D, Babashev O, Chieverdiuk D, Shchebetun A, Khyzhniak K, Pavlovskii M, Strokan A, Zemskov S (2024)
Initial experience of parenchyma-sparing liver resection with systematic selective hepatic vein reconstruction for colorectal metastases
BMJ Surg Interv Health Technol, 6 (1), e000302
DOI 10.1136/bmjsit-2024-000302, PubMed 39687210

Publications 2023

Aghayan DL, Kazaryan AM, Fretland ÅA, Edwin B (2023)
Difficult procedures, better outcomes
Hepatobiliary Surg Nutr, 12 (4), 634-636
DOI 10.21037/hbsn-23-302, PubMed 37600980

Ghotbi J, Aghayan D, Fretland Å, Edwin B, Syn NL, Cipriani F, Alzoubi M, Lim C, Scatton O, Long TCD, Herman P, Coelho FF, Marino MV, Mazzaferro V, Chiow AKH, Sucandy I, Ivanecz A, Choi SH, Lee JH, Prieto M, Vivarelli M, Giuliante F, Ruzzenente A, Yong CC, Yin M et al. (2023)
Impact of neoadjuvant chemotherapy on the difficulty and outcomes of laparoscopic and robotic major liver resections for colorectal liver metastases: A propensity-score and coarsened exact-matched controlled study
Eur J Surg Oncol, 49 (7), 1209-1216
DOI 10.1016/j.ejso.2023.01.014, PubMed 36774216

Görgec B, Hansen IS, Kemmerich G, Syversveen T, Abu Hilal M, Belt EJT, Bosscha K, Burgmans MC, Cappendijk VC, D'Hondt M, Edwin B, van Erkel AR, Gielkens HAJ, Grünhagen DJ, Gobardhan PD, Hartgrink HH, Horsthuis K, Klompenhouwer EG, Kok NFM, Kint PAM, Kuhlmann K, Leclercq WKG, Lips DJ, Lutin B, Maas M et al. (2023)
MRI in addition to CT in patients scheduled for local therapy of colorectal liver metastases (CAMINO): an international, multicentre, prospective, diagnostic accuracy trial
Lancet Oncol, 25 (1), 137-146
DOI 10.1016/S1470-2045(23)00572-7, PubMed 38081200

Krenzien F, Schmelzle M, Pratschke J, Feldbrügge L, Liu R, Liu Q, Zhang W, Zhao JJ, Tan HL, Cipriani F, Hoogteijling TJ, Aghayan DL, Fretland ÅA, Siow TF, Lim C, Scatton O, Herman P, Coelho FF, Marino MV, Mazzaferro V, Chiow AKH, Sucandy I, Ivanecz A, Choi SH, Lee JH et al. (2023)
Propensity Score-Matching Analysis Comparing Robotic Versus Laparoscopic Limited Liver Resections of the Posterosuperior Segments: An International Multicenter Study
Ann Surg, 279 (2), 297-305
DOI 10.1097/SLA.0000000000006027, PubMed 37485989

Lof S, Claassen L, Hannink G, Al-Sarireh B, Björnsson B, Boggi U, Burdio F, Butturini G, Capretti G, Casadei R, Dokmak S, Edwin B, Esposito A, Fabre JM, Ferrari G, Fretland AA, Ftériche FS, Fusai GK, Giardino A, Groot Koerkamp B, D'Hondt M, Jah A, Kamarajah SK, Kauffmann EF, Keck T et al. (2023)
Learning Curves of Minimally Invasive Distal Pancreatectomy in Experienced Pancreatic Centers
JAMA Surg, 158 (9), 927-933
DOI 10.1001/jamasurg.2023.2279, PubMed 37378968

Nygaard V, Ree AH, Dagenborg VJ, Børresen-Dale AL, Edwin B, Fretland ÅA, Grzyb K, Haugen MH, Mælandsmo GM, Flatmark K (2023)
A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases
Cancer Res Commun, 3 (2), 235-244
DOI 10.1158/2767-9764.CRC-22-0295, PubMed 36968142

Pereira PL, Bale R, Fretland ÅA, Goldberg SN, Helmberger T, Meijerink MR, Orsi F, Stättner S, Vogl T, Kafkoula A, de Jong N, Zeka B, de Baère T (2023)
Local Tumour Control Following Microwave Ablation: Protocol for the Prospective Observational CIEMAR Study
Cardiovasc Intervent Radiol, 47 (1), 121-129
DOI 10.1007/s00270-023-03573-0, PubMed 37884801

Siriwardena AK, Serrablo A, Fretland ÅA, Wigmore SJ, Ramia-Angel JM, Malik HZ, Stättner S, Søreide K, Zmora O, Meijerink M, Kartalis N, Lesurtel M, Verhoef C, Balakrishnan A, Gruenberger T, Jonas E, Devar J, Jamdar S, Jones R, Hilal MA, Andersson B, Boudjema K, Mullamitha S, Stassen L, Dasari BVM et al. (2023)
The multi-societal European consensus on the terminology, diagnosis and management of patients with synchronous colorectal cancer and liver metastases: an E-AHPBA consensus in partnership with ESSO, ESCP, ESGAR, and CIRSE
HPB (Oxford), 25 (9), 985-999
DOI 10.1016/j.hpb.2023.05.360, PubMed 37471055

Siriwardena AK, Serrablo A, Fretland ÅA, Wigmore SJ, Ramia-Angel JM, Malik HZ, Stättner S, Søreide K, Zmora O, Meijerink M, Kartalis N, Lesurtel M, Verhoef K, Balakrishnan A, Gruenberger T, Jonas E, Devar J, Jamdar S, Jones R, Hilal MA, Andersson B, Boudjema K, Mullamitha S, Stassen L, Dasari BVM et al. (2023)
Multisocietal European consensus on the terminology, diagnosis, and management of patients with synchronous colorectal cancer and liver metastases: an E-AHPBA consensus in partnership with ESSO, ESCP, ESGAR, and CIRSE
Br J Surg, 110 (9), 1161-1170
DOI 10.1093/bjs/znad124, PubMed 37442562

van der Heijde N, Görgec B, Beane JD, Ratti F, Belli G, Benedetti Cacciaguerra A, Calise F, Cillo U, De Boer MT, Fagenson AM, Fretland ÅA, Gleeson EM, de Graaff MR, Kok NFM, Lassen K, van der Poel MJ, Ruzzenente A, Sutcliffe RP, Edwin B, Aldrighetti L, Pitt HA, Abu Hilal M, Besselink MG (2023)
Transatlantic registries for minimally invasive liver surgery: towards harmonization
Surg Endosc, 37 (5), 3580-3592
DOI 10.1007/s00464-022-09765-y, PubMed 36624213

van der Heijde N, Görgec B, Beane JD, Ratti F, Belli G, Benedetti Cacciaguerra A, Calise F, Cillo U, De Boer MT, Fagenson AM, Fretland ÅA, Gleeson EM, de Graaff MR, Kok NFM, Lassen K, van der Poel MJ, Ruzzenente A, Sutcliffe RP, Edwin B, Aldrighetti L, Pitt HA, Abu Hilal M, Besselink MG (2023)
Correction: Transatlantic registries for minimally invasive liver surgery: towards harmonization
Surg Endosc, 37 (5), 4112
DOI 10.1007/s00464-023-09887-x, PubMed 36717429

Publications 2022

Aghayan DL, d'Albenzio G, Fretland ÅA, Pelanis E, Røsok BI, Yaqub S, Palomar R, Edwin B (2022)
Laparoscopic parenchyma-sparing liver resection for large (≥ 50 mm) colorectal metastases
Surg Endosc, 37 (1), 225-233
DOI 10.1007/s00464-022-09493-3, PubMed 35922606

Carling U, Røsok B, Berger S, Fretland ÅA, Dorenberg E (2022)
Reply to Letter to the Editor: Portal Vein Embolization with Vascular Plug and n-Butyl Cyanoacrylate: Are We There Yet?
Cardiovasc Intervent Radiol, 45 (10), 1549-1550
DOI 10.1007/s00270-022-03239-3, PubMed 36008573

Efanov M, Salimgereeva D, Alikhanov R, Wu AGR, Geller D, Cipriani F, Aghayan DL, Fretland AA, Sijberden J, Belli A, Marino MV, Mazzaferro V, Chiow AKH, Sucandy I, Ivanecz A, Choi SH, Lee JH, Prieto M, Vivarelli M, Giuliante F, Ruzzenente A, Yong CC, Fondevila C, Rotellar F, Choi GH et al. (2022)
Comparison between the difficulty of laparoscopic limited liver resections of tumors located in segment 7 versus segment 8: An international multicenter propensity-score matched study
J Hepatobiliary Pancreat Sci, 30 (2), 177-191
DOI 10.1002/jhbp.1210, PubMed 35758911

Gholinejad M, Pelanis E, Aghayan D, Fretland ÅA, Edwin B, Terkivatan T, Elle OJ, Loeve AJ, Dankelman J (2022)
Generic surgical process model for minimally invasive liver treatment methods
Sci Rep, 12 (1), 16684
DOI 10.1038/s41598-022-19891-1, PubMed 36202857

Ghotbi J, Sahakyan M, Søreide K, Fretland ÅA, Røsok B, Tholfsen T, Waage A, Edwin B, Labori KJ, Yaqub S, Kleive D (2022)
Minimally Invasive Pancreatoduodenectomy: Contemporary Practice, Evidence, and Knowledge Gaps
Oncol Ther, 10 (2), 301-315
DOI 10.1007/s40487-022-00203-6, PubMed 35829933

Goh BKP, Han HS, Chen KH, Chua DW, Chan CY, Cipriani F, Aghayan DL, Fretland AA, Sijberden J, D'Silva M, Siow TF, Kato Y, Lim C, Nghia PP, Herman P, Marino MV, Mazzaferro V, Chiow AKH, Sucandy I, Ivanecz A, Choi SH, Lee JH, Gastaca M, Vivarelli M, Giuliante F et al. (2022)
Defining Global Benchmarks for Laparoscopic Liver Resections: An International Multicenter Study
Ann Surg, 277 (4), e839-e848
DOI 10.1097/SLA.0000000000005530, PubMed 35837974

Høye E, Dagenborg VJ, Torgunrud A, Lund-Andersen C, Fretland ÅA, Lorenz S, Edwin B, Hovig E, Fromm B, Inderberg EM, Greiff V, Ree AH, Flatmark K (2022)
T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases
Gigascience, 12
DOI 10.1093/gigascience/giad032, PubMed 37161965

Høye E, Fromm B, Böttger PHM, Domanska D, Torgunrud A, Lund-Andersen C, Abrahamsen TW, Fretland ÅA, Dagenborg VJ, Lorenz S, Edwin B, Hovig E, Flatmark K (2022)
A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer
NAR Cancer, 4 (1), zcab051
DOI 10.1093/narcan/zcab051, PubMed 35047825

Sahakyan MA, Aghayan DL, Edwin B, Alikhanov R, Britskaia N, Brudvik KW, D'Hondt M, De Meyere C, Efanov M, Fretland ÅA, Hoff R, Ismail W, Ivanecz A, Kazaryan AM, Lassen K, Magdalenić T, Parmentier I, Røsok BI, Villanger O, Yaqub S (2022)
Laparoscopic versus open liver resection for intrahepatic cholangiocarcinoma: a multicenter propensity score-matched study
Scand J Gastroenterol, 58 (5), 489-496
DOI 10.1080/00365521.2022.2143724, PubMed 36373379

Publications 2021

Aghayan DL, Fretland ÅA, Edwin B (2021)
Survival after laparoscopic versus open resection for colorectal liver metastases
Hepatobiliary Surg Nutr, 10 (1), 134-135
DOI 10.21037/hbsn-20-796, PubMed 33575305

Aghayan DL, Kazaryan AM, Fretland ÅA, Røsok B, Barkhatov L, Lassen K, Edwin B (2021)
Evolution of laparoscopic liver surgery: 20-year experience of a Norwegian high-volume referral center
Surg Endosc, 36 (5), 2818-2826
DOI 10.1007/s00464-021-08570-3, PubMed 34036419

Barkhatov L, Aghayan DL, Scuderi V, Cipriani F, Fretland ÅA, Kazaryan AM, Ratti F, Armstrong T, Belli A, Dagher I, Belli G, Aldrighetti L, Hilal MA, Troisi RI, Edwin B (2021)
Long-term oncological outcomes after laparoscopic parenchyma-sparing redo liver resections for patients with metastatic colorectal cancer: a European multi-center study
Surg Endosc, 36 (5), 3374-3381
DOI 10.1007/s00464-021-08655-z, PubMed 34462867

Carling U, Røsok B, Berger S, Fretland ÅA, Dorenberg E (2021)
Portal Vein Embolization Using N-Butyl Cyanoacrylate-Glue: What Impact Does a Central Vascular Plug Have?
Cardiovasc Intervent Radiol, 45 (4), 450-458
DOI 10.1007/s00270-021-03014-w, PubMed 34907454

Dagenborg VJ, Marshall SE, Grzyb K, Fretland ÅA, Lund-Iversen M, Mælandsmo GM, Ree AH, Edwin B, Yaqub S, Flatmark K (2021)
Low Concordance Between T-Cell Densities in Matched Primary Tumors and Liver Metastases in Microsatellite Stable Colorectal Cancer
Front Oncol, 11, 671629
DOI 10.3389/fonc.2021.671629, PubMed 34178659

Görgec B, Fichtinger RS, Ratti F, Aghayan D, Van der Poel MJ, Al-Jarrah R, Armstrong T, Cipriani F, Fretland ÅA, Suhool A, Bemelmans M, Bosscha K, Braat AE, De Boer MT, Dejong CHC, Doornebosch PG, Draaisma WA, Gerhards MF, Gobardhan PD, Hagendoorn J, Kazemier G, Klaase J, Leclercq WKG, Liem MS, Lips DJ et al. (2021)
Comparing practice and outcome of laparoscopic liver resection between high-volume expert centres and nationwide low-to-medium volume centres
Br J Surg, 108 (8), 983-990
DOI 10.1093/bjs/znab096, PubMed 34195799

Görgec B, Hansen I, Kemmerich G, Syversveen T, Abu Hilal M, Belt EJT, Bisschops RHC, Bollen TL, Bosscha K, Burgmans MC, Cappendijk V, De Boer MT, D'Hondt M, Edwin B, Gielkens H, Grünhagen DJ, Gillardin P, Gobardhan PD, Hartgrink HH, Horsthuis K, Kok NFM, Kint PAM, Kruimer JWH, Leclercq WKG, Lips DJ et al. (2021)
Clinical added value of MRI to CT in patients scheduled for local therapy of colorectal liver metastases (CAMINO): study protocol for an international multicentre prospective diagnostic accuracy study
BMC Cancer, 21 (1), 1116
DOI 10.1186/s12885-021-08833-1, PubMed 34663243

Heil J, Heid F, Bechstein WO, Björnsson B, Brismar TB, Carling U, Erdmann J, Fretland ÅA, Grunhagen D, Hana RA, Hohmann J, Linke R, Meyer Y, Nawawi A, Olthof PB, Sandström P, Schnitzbauer AA, Sparrelid E, Verhoef C, Metrakos P, Schadde E (2021)
Sarcopenia predicts reduced liver growth and reduced resectability in patients undergoing portal vein embolization before liver resection - A DRAGON collaborative analysis of 306 patients
HPB (Oxford), 24 (3), 413-421
DOI 10.1016/j.hpb.2021.08.818, PubMed 34526229

Publications 2020

Aghayan DL, Kazaryan AM, Dagenborg VJ, Røsok BI, Fagerland MW, Waaler Bjørnelv GM, Kristiansen R, Flatmark K, Fretland ÅA, Edwin B, OSLO-COMET Survival Study Collaborators (2020)
Long-Term Oncologic Outcomes After Laparoscopic Versus Open Resection for Colorectal Liver Metastases : A Randomized Trial
Ann Intern Med, 174 (2), 175-182
DOI 10.7326/M20-4011, PubMed 33197213

Bjørnelv GMW, Edwin B, Fretland ÅA, Deb P, Aas E (2020)
Till death do us part: the effect of marital status on health care utilization and costs at end-of-life. A register study on all colorectal cancer decedents in Norway between 2009 and 2013
BMC Health Serv Res, 20 (1), 115
DOI 10.1186/s12913-019-4794-6, PubMed 32054492

Brun H, Pelanis E, Wiig O, Luzon JA, Birkeland S, Kumar RP, Fretland ÅA, Suther KR, Edwin B, Elle OJ (2020)
Mixed reality - new image technology in experimental use
Tidsskr Nor Laegeforen, 140 (17)
DOI 10.4045/tidsskr.20.0498, PubMed 33231396

Dagenborg VJ, Marshall SE, Yaqub S, Grzyb K, Boye K, Lund-Iversen M, Høye E, Berstad AE, Fretland ÅA, Edwin B, Ree AH, Flatmark K (2020)
Neoadjuvant chemotherapy is associated with a transient increase of intratumoral T-cell density in microsatellite stable colorectal liver metastases
Cancer Biol Ther, 21 (5), 432-440
DOI 10.1080/15384047.2020.1721252, PubMed 32098573

Hausken J, Fretland ÅA, Edwin B, Kvarstein G, Tønnessen TI (2020)
Response to the Comment on "Epidural Analgesia (TEA) vs. IV-PCA After Open Liver Surgery"
Ann Surg, 271 (5), e126-e127
DOI 10.1097/SLA.0000000000003684, PubMed 31800498

Kazaryan AM, Aghayan DL, Fretland ÅA, Semikov VI, Shulutko AM, Edwin B (2020)
Laparoscopic liver resection with simultaneous diaphragm resection
Ann Transl Med, 8 (5), 214
DOI 10.21037/atm.2020.01.62, PubMed 32309361

Kazaryan AM, Edwin B, Darzi A, Tamamyan GN, Sahakyan MA, Aghayan DL, Fretland ÅA, Yaqub S, Gayet B, Doctors Against The War collaborators (2020)
War in the time of COVID-19: humanitarian catastrophe in Nagorno-Karabakh and Armenia
Lancet Glob Health, 9 (3), e243-e244
DOI 10.1016/S2214-109X(20)30510-6, PubMed 33253632

Khan ZA, Beghdadi A, Cheikh FA, Kaaniche M, Pelanis E, Palomar R, Fretland AA, Edwin B, Elle OJ (2020)
Towards a Video Quality Assessment based Framework for Enhancement of Laparoscopic Videos
PROC SPIE, 11316, 113160P
DOI 10.1117/12.2549266

Kumar RP, Pelanis E, Bugge R, Brun H, Palomar R, Aghayan DL, Fretland ÅA, Edwin B, Elle OJ (2020)
Use of mixed reality for surgery planning: Assessment and development workflow
J Biomed Inform, 112S, 100077
DOI 10.1016/j.yjbinx.2020.100077, PubMed 34417006

Publications 2019

Aghayan DL, Fretland ÅA, Kazaryan AM, Sahakyan MA, Dagenborg VJ, Bjørnbeth BA, Flatmark K, Kristiansen R, Edwin B (2019)
Laparoscopic versus open liver resection in the posterosuperior segments: a sub-group analysis from the OSLO-COMET randomized controlled trial
HPB (Oxford), 21 (11), 1485-1490
DOI 10.1016/j.hpb.2019.03.358, PubMed 30962136

Aghayan DL, Kalinowski P, Kazaryan AM, Fretland ÅA, Sahakyan MA, Røsok BI, Pelanis E, Bjørnbeth BA, Edwin B (2019)
Laparoscopic liver resection for non-colorectal non-neuroendocrine metastases: perioperative and oncologic outcomes
World J Surg Oncol, 17 (1), 156
DOI 10.1186/s12957-019-1700-y, PubMed 31484583

Berardi G, Aghayan D, Fretland ÅA, Elberm H, Cipriani F, Spagnoli A, Montalti R, Ceelen WP, Aldrighetti L, Abu Hilal M, Edwin B, Troisi RI (2019)
Multicentre analysis of the learning curve for laparoscopic liver resection of the posterosuperior segments
Br J Surg, 106 (11), 1512-1522
DOI 10.1002/bjs.11286, PubMed 31441944

Brudvik KW, Jones RP, Giuliante F, Shindoh J, Passot G, Chung MH, Song J, Li L, Dagenborg VJ, Fretland ÅA, Røsok B, De Rose AM, Ardito F, Edwin B, Panettieri E, Larocca LM, Yamashita S, Conrad C, Aloia TA, Poston GJ, Bjørnbeth BA, Vauthey JN (2019)
RAS Mutation Clinical Risk Score to Predict Survival After Resection of Colorectal Liver Metastases
Ann Surg, 269 (1), 120-126
DOI 10.1097/SLA.0000000000002319, PubMed 28549012

Ciria R, Ocaña S, Gomez-Luque I, Cipriani F, Halls M, Fretland ÅA, Okuda Y, Aroori S, Briceño J, Aldrighetti L, Edwin B, Hilal MA (2019)
A systematic review and meta-analysis comparing the short- and long-term outcomes for laparoscopic and open liver resections for liver metastases from colorectal cancer
Surg Endosc, 34 (1), 349-360
DOI 10.1007/s00464-019-06774-2, PubMed 30989374

Fretland ÅA, Dagenborg VJ, Waaler Bjørnelv GM, Aghayan DL, Kazaryan AM, Barkhatov L, Kristiansen R, Fagerland MW, Edwin B, Andersen MH (2019)
Quality of life from a randomized trial of laparoscopic or open liver resection for colorectal liver metastases
Br J Surg, 106 (10), 1372-1380
DOI 10.1002/bjs.11227, PubMed 31322735

Hausken J, Fretland ÅA, Edwin B, Andersen MH, Dagenborg VJ, Bjørnelv GMW, Kristiansen R, Røysland K, Kvarstein G, Tønnessen TI (2019)
Intravenous Patient-controlled Analgesia Versus Thoracic Epidural Analgesia After Open Liver Surgery: A Prospective, Randomized, Controlled, Noninferiority Trial
Ann Surg, 270 (2), 193-199
DOI 10.1097/SLA.0000000000003209, PubMed 30676382

Kazaryan AM, Aghayan DL, Barkhatov LI, Fretland ÅA, Edwin B (2019)
Laparoscopic Multiple Parenchyma-sparing Concomitant Liver Resections for Colorectal Liver Metastases
Surg Laparosc Endosc Percutan Tech, 29 (3), 187-193
DOI 10.1097/SLE.0000000000000606, PubMed 30520815

Pelanis E, Kumar RP, Aghayan DL, Palomar R, Fretland ÅA, Brun H, Elle OJ, Edwin B (2019)
Use of mixed reality for improved spatial understanding of liver anatomy
Minim Invasive Ther Allied Technol, 29 (3), 154-160
DOI 10.1080/13645706.2019.1616558, PubMed 31116053

Teatini A, Pelanis E, Aghayan DL, Kumar RP, Palomar R, Fretland ÅA, Edwin B, Elle OJ (2019)
The effect of intraoperative imaging on surgical navigation for laparoscopic liver resection surgery
Sci Rep, 9 (1), 18687
DOI 10.1038/s41598-019-54915-3, PubMed 31822701

Publications 2018

Bjørnelv GMW, Dueland S, Line PD, Joranger P, Fretland ÅA, Edwin B, Sørbye H, Aas E (2018)
Cost-effectiveness of liver transplantation in patients with colorectal metastases confined to the liver
Br J Surg, 106 (1), 132-141
DOI 10.1002/bjs.10962, PubMed 30325494

Brudvik KW, Røsok B, Naresh U, Yaqub S, Fretland ÅA, Labori KJ, Edwin B, Bjørnbeth BA (2018)
Survival after resection of colorectal liver metastases in octogenarians and sexagenarians compared to their respective age-matched national population
Hepatobiliary Surg Nutr, 7 (4), 234-241
DOI 10.21037/hbsn.2017.09.03, PubMed 30221151

Fretland ÅA, Dagenborg VJ, Bjørnelv GMW, Kazaryan AM, Kristiansen R, Fagerland MW, Hausken J, Tønnessen TI, Abildgaard A, Barkhatov L, Yaqub S, Røsok BI, Bjørnbeth BA, Andersen MH, Flatmark K, Aas E, Edwin B (2018)
Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial
Ann Surg, 267 (2), 199-207
DOI 10.1097/SLA.0000000000002353, PubMed 28657937

Fretland ÅA, Edwin B (2018)
Response: The OSLO-COMET Randomized Controlled Trial of Laparoscopic Versus Open Liver Resection for Colorectal Metastases
Ann Surg, 268 (6), e69-e70
DOI 10.1097/SLA.0000000000002646, PubMed 29303812

Lassen K, Nymo LS, Olsen F, Brudvik KW, Fretland ÅA, Søreide K (2018)
Contemporary practice and short-term outcomes after liver resections in a complete national cohort
Langenbecks Arch Surg, 404 (1), 11-19
DOI 10.1007/s00423-018-1737-3, PubMed 30519886

Pelanis E, Kumar R, Fretland A, Elle OJ, Edwin B (2018)
An early assessment for the use of HoloLens during laparoscopic liver resections
HPB, 20, S239
PublikaID 331

Sahakyan MA, Røsok BI, Kleive D, Fretland ÅA, Kazaryan AM, Labori KJ, Edwin B (2018)
The European Experience in Laparoscopic Pancreatic Resections
J Am Coll Surg, 226 (1), 104
DOI 10.1016/j.jamcollsurg.2017.10.003, PubMed 29274644

Publications 2017

Aghayan DL, Kazaryan AM, Fretland ÅA, Sahakyan MA, Røsok BI, Bjørnbeth BA, Edwin B (2017)
Laparoscopic liver resection for metastatic melanoma
Surg Endosc, 32 (3), 1470-1477
DOI 10.1007/s00464-017-5834-0, PubMed 28916919

Barkhatov L, Tyukina N, Fretland ÅA, Røsok BI, Kazaryan AM, Riis R, Edwin B (2017)
Superior mesenteric artery syndrome: quality of life after laparoscopic duodenojejunostomy
Clin Case Rep, 6 (2), 323-329
DOI 10.1002/ccr3.1242, PubMed 29445471

Berardi G, Van Cleven S, Fretland ÅA, Barkhatov L, Halls M, Cipriani F, Aldrighetti L, Abu Hilal M, Edwin B, Troisi RI (2017)
Evolution of Laparoscopic Liver Surgery from Innovation to Implementation to Mastery: Perioperative and Oncologic Outcomes of 2,238 Patients from 4 European Specialized Centers
J Am Coll Surg, 225 (5), 639-649
DOI 10.1016/j.jamcollsurg.2017.08.006, PubMed 28838869

Fretland ÅA, Kazaryan AM, Edwin B (2017)
Laparoscopic Resection for Liver Malignancies: Do the Elderly Benefit More?
J Invest Surg, 32 (1), 83-84
DOI 10.1080/08941939.2017.1385664, PubMed 29115882

Palomar R, Cheikh FA, Edwin B, Fretland Å, Beghdadi A, Elle OJ (2017)
A novel method for planning liver resections using deformable Bézier surfaces and distance maps
Comput Methods Programs Biomed, 144, 135-145
DOI 10.1016/j.cmpb.2017.03.019, PubMed 28494998

Østrup O, Dagenborg VJ, Rødland EA, Skarpeteig V, Silwal-Pandit L, Grzyb K, Berstad AE, Fretland ÅA, Mælandsmo GM, Børresen-Dale AL, Ree AH, Edwin B, Nygaard V, Flatmark K (2017)
Molecular signatures reflecting microenvironmental metabolism and chemotherapy-induced immunogenic cell death in colorectal liver metastases
Oncotarget, 8 (44), 76290-76304
DOI 10.18632/oncotarget.19350, PubMed 29100312

Publications 2016

Barkhatov L, Fretland ÅA, Kazaryan AM, Røsok BI, Brudvik KW, Waage A, Bjørnbeth BA, Sahakyan MA, Edwin B (2016)
Validation of clinical risk scores for laparoscopic liver resections of colorectal liver metastases: A 10-year observed follow-up study
J Surg Oncol, 114 (6), 757-763
DOI 10.1002/jso.24391, PubMed 27471127

Sahakyan MA, Røsok BI, Kazaryan AM, Barkhatov L, Haugvik SP, Fretland ÅA, Ignjatovic D, Labori KJ, Edwin B (2016)
Role of laparoscopic enucleation in the treatment of pancreatic lesions: case series and case-matched analysis
Surg Endosc, 31 (5), 2310-2316
DOI 10.1007/s00464-016-5233-y, PubMed 27620912

Publications 2015

Di Fabio F, Barkhatov L, Bonadio I, Dimovska E, Fretland AA, Pearce NW, Troisi RI, Edwin B, Abu Hilal M (2015)
The impact of laparoscopic versus open colorectal cancer surgery on subsequent laparoscopic resection of liver metastases: A multicenter study (vol 157, pg 1046, 2015)
Surgery, 158 (5), 1450
DOI 10.1016/j.surg.2015.06.020

Di Fabio F, Barkhatov L, Bonadio I, Dimovska E, Fretland ÅA, Pearce NW, Troisi RI, Edwin B, Abu Hilal M (2015)
The impact of laparoscopic versus open colorectal cancer surgery on subsequent laparoscopic resection of liver metastases: A multicenter study
Surgery, 157 (6), 1046-54
DOI 10.1016/j.surg.2015.01.007, PubMed 25835216

Fretland AA, Sokolov A, Postriganova N, Kazaryan AM, Pischke SE, Nilsson PH, Rognes IN, Bjornbeth BA, Fagerland MW, Mollnes TE, Edwin B (2015)
Inflammatory Response After Laparoscopic Versus Open Resection of Colorectal Liver Metastases: Data From the Oslo-CoMet Trial
Medicine (Baltimore), 94 (42), e1786
DOI 10.1097/MD.0000000000001786, PubMed 26496309

Fretland ÅA, Kazaryan AM, Bjørnbeth BA, Flatmark K, Andersen MH, Tønnessen TI, Bjørnelv GM, Fagerland MW, Kristiansen R, Øyri K, Edwin B (2015)
Open versus laparoscopic liver resection for colorectal liver metastases (the Oslo-CoMet Study): study protocol for a randomized controlled trial
Trials, 16, 73
DOI 10.1186/s13063-015-0577-5, PubMed 25872027

Publications 2014

Afridi SA, Kazaryan AM, Marangos IP, Røsok BI, Fretland ÅA, Yaqub S, Edwin B (2014)
Laparoscopic surgery for solid pseudopapillary tumor of the pancreas
JSLS, 18 (2), 236-42
DOI 10.4293/108680813X13753907291837, PubMed 24960486

Publications 2013

Postriganova N, Kazaryan AM, Røsok BI, Fretland Å, Barkhatov L, Edwin B (2013)
Margin status after laparoscopic resection of colorectal liver metastases: does a narrow resection margin have an influence on survival and local recurrence?
HPB (Oxford), 16 (9), 822-9
DOI 10.1111/hpb.12204, PubMed 24308605

Publications 2005

Fretland AA (2005)
[Antibiotic prophylaxis in acute pancreatitis--is the evidence good enough?]
Tidsskr Nor Laegeforen, 125 (10), 1323-5
PubMed 15909002