Bjørn Atle Bjørnbeth
- CEO Oslo University Hospital; Dr. med.
Publications 2024
Long-Term Follow-Up of Patients with Advanced Colorectal Liver Metastasis: A Survival Analysis from the Randomized Controlled Multicenter Trial LIGRO
Ann Surg Open, 5 (3), e455
DOI 10.1097/AS9.0000000000000455, PubMed 39310365
Health Economic Evaluation of Patients With Colorectal Liver Metastases Randomized to ALPPS or TSH: Analysis From the LIGRO Trial
Ann Surg Open, 5 (1), e367
DOI 10.1097/AS9.0000000000000367, PubMed 38883960
Publications 2021
Genomic and prognostic heterogeneity among RAS/BRAFV600E /TP53 co-mutated resectable colorectal liver metastases
Mol Oncol, 15 (4), 830-845
DOI 10.1002/1878-0261.12885, PubMed 33325154
Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer
NPJ Genom Med, 6 (1), 59
DOI 10.1038/s41525-021-00223-7, PubMed 34262039
ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM: Survival Analysis From the Randomized Controlled Trial LIGRO
Ann Surg, 273 (3), 442-448
DOI 10.1097/SLA.0000000000003701, PubMed 32049675
Response to the Comment on "ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM: Survival Analysis From the Randomized Controlled Trial LIGRO-Metastatic Tumor Burden in the Future Liver Remnant for Decision-making of Staged Hepatectomy"
Ann Surg, 274 (6), e750-e751
DOI 10.1097/SLA.0000000000004014, PubMed 32590545
Response to Comment on "ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM - It Is Time to Entry the IDEAL Stage 4?"
Ann Surg, 274 (6), e731-e732
DOI 10.1097/SLA.0000000000004357, PubMed 33234782
Response to Comment on: Hasselgren K, et al ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM: Survival Analysis From the Randomized Controlled Trial LIGRO. Ann Surg. 2021;273(3):442-448
Ann Surg, 276 (5), e632-e633
DOI 10.1097/SLA.0000000000005268, PubMed 35129514
Early detection of anastomotic leakage after pancreatoduodenectomy with microdialysis catheters: an observational Study
HPB (Oxford), 24 (6), 901-909
DOI 10.1016/j.hpb.2021.10.020, PubMed 34836755
De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
Genome Med, 13 (1), 143
DOI 10.1186/s13073-021-00956-1, PubMed 34470666
The expressed mutational landscape of microsatellite stable colorectal cancers
Genome Med, 13 (1), 142
DOI 10.1186/s13073-021-00955-2, PubMed 34470667
Aspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial
Trials, 22 (1), 642
DOI 10.1186/s13063-021-05587-w, PubMed 34544470
Publications 2020
Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
Clin Cancer Res, 26 (15), 4107-4119
DOI 10.1158/1078-0432.CCR-19-3637, PubMed 32299813
Survival Following Liver Transplantation for Patients With Nonresectable Liver-only Colorectal Metastases
Ann Surg, 271 (2), 212-218
DOI 10.1097/SLA.0000000000003404, PubMed 31188200
Publications 2019
Laparoscopic versus open liver resection in the posterosuperior segments: a sub-group analysis from the OSLO-COMET randomized controlled trial
HPB (Oxford), 21 (11), 1485-1490
DOI 10.1016/j.hpb.2019.03.358, PubMed 30962136
Laparoscopic liver resection for non-colorectal non-neuroendocrine metastases: perioperative and oncologic outcomes
World J Surg Oncol, 17 (1), 156
DOI 10.1186/s12957-019-1700-y, PubMed 31484583
RAS Mutation Clinical Risk Score to Predict Survival After Resection of Colorectal Liver Metastases
Ann Surg, 269 (1), 120-126
DOI 10.1097/SLA.0000000000002319, PubMed 28549012
Heterogeneous radiological response to neoadjuvant therapy is associated with poor prognosis after resection of colorectal liver metastases
Eur J Surg Oncol, 45 (12), 2340-2346
DOI 10.1016/j.ejso.2019.07.017, PubMed 31350075
High Concordance and Negative Prognostic Impact of RAS/BRAF/PIK3CA Mutations in Multiple Resected Colorectal Liver Metastases
Clin Colorectal Cancer, 19 (1), e26-e47
DOI 10.1016/j.clcc.2019.09.003, PubMed 31982351
Characterization of early recurrences following liver resection by ALPPS and two stage hepatectomy in patients with colorectal liver-metastases and small future liver remnants; a translational substudy of the LIGRO-RCT
HPB (Oxford), 21 (8), 1017-1023
DOI 10.1016/j.hpb.2018.12.003, PubMed 30765198
Response to Comment on "When Innovation Is Not Enough"
Ann Surg, 270 (2), e36-e37
DOI 10.1097/SLA.0000000000003028, PubMed 30169399
Response to "ALPPS Versus Conventional Two-stage Hepatectomy in Patients With Advanced Colorectal Liver Metastases"
Ann Surg, 269 (1), e16-e17
DOI 10.1097/SLA.0000000000003046, PubMed 30247325
Response to the Comment on "Should We Have a Little More Patience With the Conventional 2-Stage Hepatectomy?"
Ann Surg, 269 (3), e33-e34
DOI 10.1097/SLA.0000000000002739, PubMed 29557882
Publications 2018
Survival after resection of colorectal liver metastases in octogenarians and sexagenarians compared to their respective age-matched national population
Hepatobiliary Surg Nutr, 7 (4), 234-241
DOI 10.21037/hbsn.2017.09.03, PubMed 30221151
Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial
Ann Surg, 267 (2), 199-207
DOI 10.1097/SLA.0000000000002353, PubMed 28657937
Future Liver Remnant (FLR) Increase in Patients with Colorectal Liver Metastases Is Highest the First Week After Portal Vein Occlusion : FLR Increase in Patients with CRLM Is Highest the First Week After PVO
J Gastrointest Surg, 23 (3), 556-562
DOI 10.1007/s11605-018-4031-3, PubMed 30465187
The New National Registry for Gastrointestinal Surgery in Norway: NoRGast
Scand J Surg, 107 (3), 201-207
DOI 10.1177/1457496918766697, PubMed 29628007
Short-term outcomes after elective colon cancer surgery: an observational study from the Norwegian registry for gastrointestinal and HPB surgery, NoRGast
Surg Endosc, 33 (9), 2821-2833
DOI 10.1007/s00464-018-6575-4, PubMed 30413929
ALPPS Improves Resectability Compared With Conventional Two-stage Hepatectomy in Patients With Advanced Colorectal Liver Metastasis: Results From a Scandinavian Multicenter Randomized Controlled Trial (LIGRO Trial)
Ann Surg, 267 (5), 833-840
DOI 10.1097/SLA.0000000000002511, PubMed 28902669
Publications 2017
Laparoscopic liver resection for metastatic melanoma
Surg Endosc, 32 (3), 1470-1477
DOI 10.1007/s00464-017-5834-0, PubMed 28916919
Laparoscopic Parenchyma-sparing Liver Resection for Colorectal Metastases
Radiol Oncol, 52 (1), 36-41
DOI 10.1515/raon-2017-0046, PubMed 29520204
Resection of synchronous liver metastases between radiotherapy and definitive surgery for locally advanced rectal cancer: short-term surgical outcomes, overall survival and recurrence-free survival
Colorectal Dis, 19 (8), 731-738
DOI 10.1111/codi.13622, PubMed 28181384
Trump's ban on colleagues from Islamic countries
Lancet, 389 (10071), 804
DOI 10.1016/S0140-6736(17)30323-9, PubMed 28187914
Improving the safety of associating liver partition and portal vein ligation for staged hepatectomy
Transl. Cancer Res., 6 3, S560-S563
DOI 10.21037/tcr.2017.04.17
Survival Impact of Primary Tumor Lymph Node Status and Circulating Tumor Cells in Patients with Colorectal Liver Metastases
Ann Surg Oncol, 24 (8), 2113-2121
DOI 10.1245/s10434-017-5818-2, PubMed 28258416
Publications 2016
Aspirin As Secondary Prevention in Patients With Colorectal Cancer: An Unselected Population-Based Study
J Clin Oncol, 34 (21), 2501-8
DOI 10.1200/JCO.2015.65.3519, PubMed 27247217
Reply to M. Løberg et al
J Clin Oncol, 35 (5), 569-571
DOI 10.1200/JCO.2016.70.8263, PubMed 29236616
Validation of clinical risk scores for laparoscopic liver resections of colorectal liver metastases: A 10-year observed follow-up study
J Surg Oncol, 114 (6), 757-763
DOI 10.1002/jso.24391, PubMed 27471127
Associating liver partition and portal vein ligation for staged hepatectomy in patients with colorectal liver metastases--Intermediate oncological results
Eur J Surg Oncol, 42 (4), 531-7
DOI 10.1016/j.ejso.2015.12.013, PubMed 26830731
Proximal signaling responses in peripheral T cells from colorectal cancer patients are affected by high concentrations of circulating prostaglandin E2
Hum Immunol, 78 (2), 129-137
DOI 10.1016/j.humimm.2016.10.007, PubMed 27769746
Laparoscopic Resection of Recurrence from Hepatocellular Carcinoma after Liver Transplantation: Case Reports and Review of the Literature
Case Rep Oncol Med, 2016, 8946471
DOI 10.1155/2016/8946471, PubMed 27034867
Publications 2015
Detection of Circulating Tumor Cells at Surgery and at Follow-Up Assessment to Predict Survival After Two-Stage Liver Resection of Colorectal Liver Metastases
Ann Surg Oncol, 22 (12), 4029-37
DOI 10.1245/s10434-015-4482-7, PubMed 25801354
Inflammatory Response After Laparoscopic Versus Open Resection of Colorectal Liver Metastases: Data From the Oslo-CoMet Trial
Medicine (Baltimore), 94 (42), e1786
DOI 10.1097/MD.0000000000001786, PubMed 26496309
Open versus laparoscopic liver resection for colorectal liver metastases (the Oslo-CoMet Study): study protocol for a randomized controlled trial
Trials, 16, 73
DOI 10.1186/s13063-015-0577-5, PubMed 25872027
Impact of early disease progression and surgical complications on adjuvant chemotherapy completion rates and survival in patients undergoing the surgery first approach for resectable pancreatic ductal adenocarcinoma - A population-based cohort study
Acta Oncol, 55 (3), 265-77
DOI 10.3109/0284186X.2015.1068445, PubMed 26213211
Radiofrequency ablation of unresectable colorectal liver metastases: trends in management and outcome during a decade at a single center
Acta Radiol Open, 4 (7), 2058460115580877
DOI 10.1177/2058460115580877, PubMed 26346740
Scandinavian multicenter study on the safety and feasibility of the associating liver partition and portal vein ligation for staged hepatectomy procedure
Surgery, 159 (5), 1279-86
DOI 10.1016/j.surg.2015.10.004, PubMed 26606881
Circulating tumor cells in patients with colorectal liver metastasis predict impaired survival
Ann Surg, 261 (1), 164-71
DOI 10.1097/SLA.0000000000000580, PubMed 24509211
Publications 2014
[Liver cyst from the East]
Tidsskr Nor Laegeforen, 134 (7), 716
DOI 10.4045/tidsskr.13.1480, PubMed 24721860
Publications 2013
Aggressive treatment of patients with metastatic colorectal cancer increases survival: a scandinavian single-center experience
HPB Surg, 2013, 727095
DOI 10.1155/2013/727095, PubMed 23840074
Publications 2012
Kinetics and activation requirements of contact-dependent immune suppression by human regulatory T cells
J Immunol, 188 (11), 5459-66
DOI 10.4049/jimmunol.1101367, PubMed 22539784
Impact of contrast-enhanced intraoperative ultrasound on operation strategy in case of colorectal liver metastasis
Acta Radiol, 53 (10), 1081-7
DOI 10.1258/ar.2012.120049, PubMed 23081954
Publications 2011
Regulatory T-cell-mediated inhibition of antitumor immune responses is associated with clinical outcome in patients with liver metastasis from colorectal cancer
Cancer Immunol Immunother, 61 (7), 1045-53
DOI 10.1007/s00262-011-1174-4, PubMed 22159472
Publications 2008
Transcatheter arterial embolization in the management of bleeding duodenal ulcers: a 5.5-year retrospective study of treatment and outcome
Scand J Gastroenterol, 43 (2), 217-22
DOI 10.1080/00365520701676443, PubMed 18224566
Generation of highly suppressive adaptive CD8(+)CD25(+)FOXP3(+) regulatory T cells by continuous antigen stimulation
Eur J Immunol, 38 (3), 640-6
DOI 10.1002/eji.200737529, PubMed 18266270
[Surgery in liver metastases]
Tidsskr Nor Laegeforen, 128 (1), 14
PubMed 18183048
Publications 2007
Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner
Cancer Immunol Immunother, 57 (6), 813-21
DOI 10.1007/s00262-007-0417-x, PubMed 17962941
Publications 2004
[Vacuum pack technique--a good method for temporal abdominal closure]
Tidsskr Nor Laegeforen, 124 (21), 2760-2
PubMed 15534669
MRI of slow flow in artificial duct in swine
Eur Radiol, 14 (9), 1692-7
DOI 10.1007/s00330-003-2212-1, PubMed 14767600
Publications 2003
Aetiology and prognostic implication of severe jaundice in surgical trauma patients
Scand J Gastroenterol, 38 (1), 102-8
DOI 10.1080/00365520310000519, PubMed 12608472
Publications 2002
Cholestatic effect of large bilirubin loads and cholestasis protection conferred by cholic acid co-infusion: a molecular and ultrastructural study
Scand J Gastroenterol, 37 (5), 585-96
DOI 10.1080/00365520252903152, PubMed 12059062
Publications 2000
Bilirubinindusert cholestase
Institutt for eksperimentell medisinsk forskning, Universitetet i Oslo, Ullevål sykehus, Oslo, 66 s.
BIBSYS 000864005, ISBN 82-90246-56-0
Intravenous bilirubin, dibromosulfophthalein, and bromosulfophthalein infusions uncouple biliary phospholipid and cholesterol secretion from bile acid secretion by inhibiting hepatic phosphoglycoprotein-3 activity in pigs
Scand J Gastroenterol, 35 (8), 873-82
DOI 10.1080/003655200750023264, PubMed 10994628
Publications 1999
Effect of intravenous bilirubin infusion on biliary phospholipid secretion, hepatic P-glycoprotein expression, and biliary cytotoxicity in pigs
Scand J Gastroenterol, 34 (10), 1042-9
DOI 10.1080/003655299750025165, PubMed 10563676
Publications 1998
Large intravenous bilirubin loads increase the cytotoxicity of bile and lower the resistance of the canalicular membrane to cytotoxic injury and cause cholestasis in pigs
Scand J Gastroenterol, 33 (2), 201-8
DOI 10.1080/00365529850166950, PubMed 9517533
Publications 1995
Bile acids protect the liver against the cholestatic effect of large bilirubin loads
Scand J Gastroenterol, 30 (12), 1186-93
DOI 10.3109/00365529509101629, PubMed 9053972
Publications 1990
NSAID-associated gastroduodenal damage: does famotidine protection extend into the mid- and distal duodenum?
Aliment Pharmacol Ther, 4 (3), 295-303
DOI 10.1111/j.1365-2036.1990.tb00474.x, PubMed 2129490