Publications 2021

Berg KCG, Brunsell TH, Sveen A, Alagaratnam S, Bjornslett M, Hektoen M, Brudvik KW, Rosok BI, Bjornbeth BA, Nesbakken A, Lothe RA (2021)
Genomic and prognostic heterogeneity among RAS/BRAF(V600E)/TP53 co-mutated resectable colorectal liver metastases
Mol. Oncol., 15 (4), 830-845
DOI 10.1002/1878-0261.12885

Eide PW, Moosavi SH, Eilertsen IA, Brunsell TH, Langerud J, Berg KCG, Rosok BI, Bjornbeth BA, Nesbakken A, Lothe RA, Sveen A (2021)
Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer
npj Genom. Med., 6 (1), 59
DOI 10.1038/s41525-021-00223-7

Hasselgren K, Rosok BI, Larsen PN, Sparrelid E, Lindell G, Schultz NA, Bjornbeth BA, Isaksson B, Larsson AL, Rizell M, Bjornsson B, Sandstrom P (2021)
ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM Survival Analysis From the Randomized Controlled Trial LIGRO
Ann. Surg., 273 (3), 442-448
DOI 10.1097/SLA.0000000000003701

Hasselgren K, Rosok BI, Larsen PN, Sparrelid E, Lindell G, Schultz NA, Bjornbeth BA, Isaksson B, Larsson AL, Rizell M, Bjornsson B, Sandstrom P (2021)
Response to Comment on "ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM - It Is Time to Entry the IDEAL Stage 4?"
Ann. Surg., 274 (6), E731-E732

Hasselgren K, Rosok BI, Larsen PN, Sparrelid E, Lindell G, Schultz NA, Bjornbeth BA, Isaksson B, Larsson AL, Rizell M, Bjornsson B, Sandstrom P (2021)
Response to the Comment on "ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM: Survival Analysis From the Randomized Controlled Trial LIGRO-Metastatic Tumor Burden in the Future Liver Remnant for Decisionmaking of Staged Hepatectomy" Reply
Ann. Surg., 274 (6), E750-E751

Moosavi SH, Eide PW, Eilertsen IA, Brunsell TH, Berg KCG, Rosok BI, Brudvik KW, Bjornbeth BA, Guren MG, Nesbakken A, Lothe RA, Sveen A (2021)
De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
Genome Med., 13 (1), 143
DOI 10.1186/s13073-021-00956-1

Sveen A, Johannessen B, Eilertsen IA, Rosok BI, Gulla M, Eide PW, Bruun J, Kryeziu K, Meza-Zepeda LA, Myklebost O, Bjornbeth BA, Skotheim RI, Nesbakken A, Lothe RA (2021)
The expressed mutational landscape of microsatellite stable colorectal cancers
Genome Med., 13 (1), 142
DOI 10.1186/s13073-021-00955-2

Yaqub S, Bjornbeth BA, Angelsen JH, Fristrup CW, Gronbech JE, Hemmingsson O, Isaksson B, Juel IS, Larsen PN, Lindell G, Mortensen FV, Mortensen KE, Rizell M, Sandstrom P, Sandvik OM, Sparrelid E, Taflin H, Tasken K, ASAC Study grp (2021)
Aspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial
Trials, 22 (1), 642
DOI 10.1186/s13063-021-05587-w

Publications 2020

Brunsell TH, Sveen A, Bjornbeth BA, Rosok BI, Danielsen SA, Brudvik KW, Berg KCG, Johannessen B, Cengija V, Abildgaard A, Guren MG, Nesbakken A, Lothe RA (2020)
High Concordance and Negative Prognostic Impact of RAS/BRAF/PIK3CA Mutations in Multiple Resected Colorectal Liver Metastases
Clin. Colorectal Canc., 19 (1), E26-E47
DOI 10.1016/j.clcc.2019.09.003

Bruun J, Kryeziu K, Eide PW, Moosavi SH, Eilertsen IA, Langerud J, Rosok B, Totland MZ, Brunsell TH, Pellinen T, Saarela J, Bergsland CH, Palmer HG, Brudvik KW, Guren T, Dienstmann R, Guren MG, Nesbakken A, Bjornbeth BA, Sveen A, Lothe RA (2020)
Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
Clin. Cancer Res., 26 (15), 4107-4119
DOI 10.1158/1078-0432.CCR-19-3637

Dueland S, Syversveen T, Solheim JM, Solberg S, Grut H, Bjornbeth BA, Hagness M, Line PD (2020)
Survival Following Liver Transplantation for Patients With Nonresectable Liver-only Colorectal Metastases
Ann. Surg., 271 (2), 212-218
DOI 10.1097/SLA.0000000000003404

Publications 2019

Aghayan DL, Fretland AA, Kazaryan AM, Sahakyan MA, Dagenborg VJ, Bjornbeth BA, Flatmark K, Kristiansen R, Edwin B (2019)
Laparoscopic versus open liver resection in the posterosuperior segments: a sub-group analysis from the OSLO-COMET randomized controlled trial
HPB, 21 (11), 1485-1490
DOI 10.1016/j.hpb.2019.03.358

Aghayan DL, Kalinowski P, Kazaryan AM, Fretland AA, Sahakyan MA, Rosok BI, Pelanis E, Bjornbeth BA, Edwin B (2019)
Laparoscopic liver resection for non-colorectal non-neuroendocrine metastases: perioperative and oncologic outcomes
World J. Surg. Oncol., 17 (1), 156
DOI 10.1186/s12957-019-1700-y

Brudvik KW, Jones RP, Giuliante F, Shindoh J, Passot G, Chung MH, Song J, Li L, Dagenborg VJ, Fretland AA, Rosok B, De Rose AM, Ardito F, Edwin B, Panettieri E, Larocca LM, Yamashita S, Conrad C, Aloia TA, Poston GJ, Bjornbeth BA, Vauthey JN (2019)
RAS Mutation Clinical Risk Score to Predict Survival After Resection of Colorectal Liver Metastases
Ann. Surg., 269 (1), 120-126
DOI 10.1097/SLA.0000000000002319

Brunsell TH, Cengija V, Sveen A, Bjornbeth BA, Rosok BI, Brudvik KW, Guren MG, Lothe RA, Abildgaard A, Nesbakken A (2019)
Heterogeneous radiological response to neoadjuvant therapy is associated with poor prognosis after resection of colorectal liver metastases
EJSO, 45 (12), 2340-2346
DOI 10.1016/j.ejso.2019.07.017

Hasselgren K, Sandstrom P, Rosok BI, Sparrelid E, Lindell G, Larsen PN, Larsson AL, Schultz NA, Bjornbeth BA, Isaksson B, Rizell M, Bjornsson B (2019)
Future Liver Remnant (FLR) Increase in Patients with Colorectal Liver Metastases Is Highest the First Week After Portal Vein Occlusion: FLR Increase in Patients with CRLM Is Highest the First Week After PVO
J. Gastrointest. Surg., 23 (3), 556-562
DOI 10.1007/s11605-018-4031-3

Nymo LS, Norderval S, Eriksen MT, Wasmuth HH, Korner H, Bjornbeth BA, Moger T, Viste A, Lassen K (2019)
Short-term outcomes after elective colon cancer surgery: an observational study from the Norwegian registry for gastrointestinal and HPB surgery, NoRGast
Surg. Endosc., 33 (9), 2821-2833
DOI 10.1007/s00464-018-6575-4

Sandstrom P, Larsson AL, Bjornsson B, Rosok BI, Sparrelid E, Larsen PN, Schultz NA, Bjornbeth BA, Lindell G, Isaksson B, Rizell M (2019)
Response to Comment on "When Innovation Is Not Enough''
Ann. Surg., 270 (2), E36-E37
DOI 10.1097/SLA.0000000000003028

Sandstrom P, Rosok BI, Sparrelid E, Larsen PN, Larsson AL, Lindell G, Schultz NA, Bjornbeth BA, Isaksson B, Rizell M, Bjornsson B (2019)
Response to "ALPPS Versus Conventional Two-stage Hepatectomy in Patients With Advanced Colorectal Liver Metastases"
Ann. Surg., 269 (1), E16-E17
DOI 10.1097/SLA.0000000000003046

Sandstrom P, Rosok BI, Sparrelid E, Lindell G, Larsen PN, Larsson AL, Schultz NA, Bjornbeth BA, Isaksson B, Rizell M, Bjornsson B (2019)
Response to the Comment on "Should We Have a Little More Patience With the Conventional 2-Stage Hepatectomy?''
Ann. Surg., 269 (3), E33-E34
DOI 10.1097/SLA.0000000000002739

Publications 2018

Aghayan DL, Kazaryan AM, Fretland AA, Sahakyan MA, Rosok BI, Bjornbeth BA, Edwin B (2018)
Laparoscopic liver resection for metastatic melanoma
Surg. Endosc., 32 (3), 1470-1477
DOI 10.1007/s00464-017-5834-0

Aghayan DL, Pelanis E, Fretland AA, Kazaryan AM, Sahakyan MA, Rosok BI, Barkhatov L, Bjornbeth BA, Elle OJ, Edwin B (2018)
Laparoscopic parenchyma-sparing liver resection for colorectal metastases
Radiol. Oncol., 52 (1), 36-41
DOI 10.1515/raon-2017-0046

Brudvik KW, Rosok B, Naresh U, Yaqub S, Fretland AA, Labori KJ, Edwin B, Bjornbeth BA (2018)
Survival after resection of colorectal liver metastases in octogenarians and sexagenarians compared to their respective age-matched national population
Hepatobil. Surg. Nutr., 7 (4), 234-241
DOI 10.21037/hbsn.2017.09.03

Fretland AA, Dagenborg VJ, Bjornelv GMW, Kazaryan AM, Kristiansen R, Fagerland MW, Hausken J, Tonnessen TI, Abildgaard A, Barkhatov L, Yaqub S, Rosok BI, Bjornbeth BA, Andersen MH, Flatmark K, Aas E, Edwin B (2018)
Laparoscopic Versus Open Resection for Colorectal Liver Metastases The OSLO-COMET Randomized Controlled Trial
Ann. Surg., 267 (2), 199-207
DOI 10.1097/SLA.0000000000002353

Lassen K, Nymo LS, Korner H, Thon K, Grindstein T, Wasmuth HH, Moger T, Bjornbeth BA, Norderval S, Eriksen MT, Viste A (2018)
The New National Registry for Gastrointestinal Surgery in Norway: NoRGast
Scand. J. Surg., 107 (3), 201-207
DOI 10.1177/1457496918766697

Sandstrom P, Rosok BI, Sparrelid E, Larsen PN, Larsson AL, Lindell G, Schultz NA, Bjornbeth BA, Isaksson B, Rizell M, Bjornsson B (2018)
ALPPS Improves Resectability Compared With Conventional Two-stage Hepatectomy in Patients With Advanced Colorectal Liver Metastasis Results From a Scandinavian Multicenter Randomized Controlled Trial (LIGRO Trial)
Ann. Surg., 267 (5), 833-840
DOI 10.1097/SLA.0000000000002511

Publications 2017

Labori KJ, Guren MG, Brudvik KW, Rosok BI, Waage A, Nesbakken A, Larsen S, Dueland S, Edwin B, Bjornbeth BA (2017)
Resection of synchronous liver metastases between radiotherapy and definitive surgery for locally advanced rectal cancer: short-term surgical outcomes, overall survival and recurrence-free survival
Colorectal Dis., 19 (8), 731-738
DOI 10.1111/codi.13622

Lassen K, Bjornbeth BA, Line PD, Abildgaard A, Soreide JA, Mortensen K, Gronbech JE, Bringeland E, Horn A (2017)
Trump's ban on colleagues from Islamic countries
Lancet, 389 (10071), 804
DOI 10.1016/S0140-6736(17)30323-9

Line PD, Bjornbeth BA (2017)
Improving the safety of associating liver partition and portal vein ligation for staged hepatectomy
Transl. Cancer Res., 6 3, S560-S563
DOI 10.21037/tcr.2017.04.17

Mahic M, Myklebust TA, Smastuen MC, Yaqub S, Dorum LM, Bjornbeth BA, Moller B, Brudvik KW, Tasken K (2017)
Aspirin, Colorectal Cancer, and Cause of Death: A Complex Landscape Reply
J. Clin. Oncol., 35 (5), 569-+
DOI 10.1200/JCO.2016.70.8263

Moltu K, Henjum K, Oberprieler NG, Bjornbeth BA, Tasken K (2017)
Proximal signaling responses in peripheral T cells from colorectal cancer patients are affected by high concentrations of circulating prostaglandin E-2
Hum. Immunol., 78 (2), 129-137
DOI 10.1016/j.humimm.2016.10.007

Seeberg LT, Brunborg C, Waage A, Hugenschmidt H, Renolen A, Stav I, Bjornbeth BA, Borgen E, Naume B, Brudvik KW, Wiedswang G (2017)
Survival Impact of Primary Tumor Lymph Node Status and Circulating Tumor Cells in Patients with Colorectal Liver Metastases
Ann. Surg. Oncol., 24 (8), 2113-2121
DOI 10.1245/s10434-017-5818-2

Publications 2016

Bains SJ, Mahic M, Myklebust TA, Smastuen MC, Yaqub S, Dorum LM, Bjornbeth BA, Moller B, Brudvik KW, Tasken K (2016)
Aspirin As Secondary Prevention in Patients With Colorectal Cancer: An Unselected Population-Based Study
J. Clin. Oncol., 34 (21), 2501-+
DOI 10.1200/JCO.2015.65.3519

Barkhatov L, Fretland AA, Kazaryan AM, Rosok BI, Brudvik KW, Waage A, Bjornbeth BA, Sahakyan MA, Edwin B (2016)
Validation of Clinical Risk Scores for Laparoscopic Liver Resections of Colorectal Liver Metastases: A 10-Year Observed Follow-Up Study
J. Surg. Oncol., 114 (6), 757-763
DOI 10.1002/jso.24391

Bjornsson B, Sparrelid E, Rosok B, Pomianowska E, Hasselgren K, Gasslander T, Bjornbeth BA, Isaksson B, Sandstrom P (2016)
Associating liver partition and portal vein ligation for staged hepatectomy in patients with colorectal liver metastases - Intermediate oncological results
EJSO, 42 (4), 531-537
DOI 10.1016/j.ejso.2015.12.013

Labori KJ, Katz MH, Tzeng CW, Bjornbeth BA, Cvancarova M, Edwin B, Kure EH, Eide TJ, Dueland S, Buanes T, Gladhaug IP (2016)
Impact of early disease progression and surgical complications on adjuvant chemotherapy completion rates and survival in patients undergoing the surgery first approach for resectable pancreatic ductal adenocarcinoma - A population-based cohort study
Acta Oncol., 55 (3), 265-277
DOI 10.3109/0284186X.2015.1068445

Rosok BI, Bjornson B, Sparrelid E, Hasselgren K, Pomianowska E, Gasslander T, Bjornbeth BA, Isaksson B, Sandstrom P (2016)
Scandinavian multicenter study on the safety and feasibility of the associating liver partition and portal vein ligation for staged hepatectomy procedure
Surgery, 159 (5), 1279-1286
DOI 10.1016/j.surg.2015.10.004

Sahakyan MA, Kazaryan AM, Pomianowska E, Abildgaard A, Line PD, Bjornbeth BA, Edwin B, Rosok BI (2016)
Laparoscopic Resection of Recurrence from Hepatocellular Carcinoma after Liver Transplantation: Case Reports and Review of the Literature
Case Rep. Oncol. Med., 2016, 8946471
DOI 10.1155/2016/8946471

Publications 2015

Brudvik KW, Seeberg LT, Hugenschmidt H, Renolen A, Schirmer CB, Brunborg C, Bjornbeth BA, Borgen E, Naume B, Waage A, Wiedswang G (2015)
Detection of Circulating Tumor Cells at Surgery and at Follow-Up Assessment to Predict Survival After Two-Stage Liver Resection of Colorectal Liver Metastases
Ann. Surg. Oncol., 22 (12), 4029-4037
DOI 10.1245/s10434-015-4482-7

Fretland AA, Kazaryan AM, Bjornbeth BA, Flatmark K, Andersen MH, Tonnessen TI, Bjornelv GMW, Fagerland MW, Kristiansen R, Oyri K, Edwin B (2015)
Open versus laparoscopic liver resection for colorectal liver metastases (the Oslo-CoMet study): study protocol for a randomized controlled trial
Trials, 16, 73
DOI 10.1186/s13063-015-0577-5

Fretland AA, Sokolov A, Postriganova N, Kazaryan AM, Pischke SE, Nilsson PH, Rognes IN, Bjornbeth BA, Fagerland MW, Mollnes TE, Edwin B (2015)
Inflammatory Response After Laparoscopic Versus Open Resection of Colorectal Liver Metastases Data From the Oslo-CoMet Trial
Medicine (Baltimore), 94 (42), e1786
DOI 10.1097/MD.0000000000001786

Labori KJ, Schulz A, Drolsum A, Guren MG, Klow NE, Bjornbeth BA (2015)
Radiofrequency ablation of unresectable colorectal liver metastases: trends in management and outcome during a decade at a single center
Acta Radiol. Open, 4 (7)
DOI 10.1177/2058460115580877

Seeberg LT, Waage A, Brunborg C, Hugenschmidt H, Renolen A, Stav I, Bjornbeth BA, Brudvik KW, Borgen EF, Naume B, Wiedswang G (2015)
Circulating Tumor Cells in Patients With Colorectal Liver Metastasis Predict Impaired Survival
Ann. Surg., 261 (1), 164-171
DOI 10.1097/SLA.0000000000000580

Publications 2012

Brudvik KW, Henjum K, Aandahl EM, Bjornbeth BA, Tasken K (2012)
Regulatory T-cell-mediated inhibition of antitumor immune responses is associated with clinical outcome in patients with liver metastasis from colorectal cancer
Cancer Immunol. Immunother., 61 (7), 1045-1053
DOI 10.1007/s00262-011-1174-4

Hagness M, Henjum K, Landskron J, Brudvik KW, Bjornbeth BA, Foss A, Tasken K, Aandahl EM (2012)
Kinetics and Activation Requirements of Contact-Dependent Immune Suppression by Human Regulatory T Cells
J. Immunol., 188 (11), 5459-5466
DOI 10.4049/jimmunol.1101367

Schulz A, Dormagen JB, Drolsum A, Bjornbeth BA, Labori KJ, Klow NE (2012)
Impact of contrast-enhanced intraoperative ultrasound on operation strategy in case of colorectal liver metastasis
Acta Radiol., 53 (10), 1081-1087
DOI 10.1258/ar.2012.120049

Publications 2008

Larssen L, Moger T, Bjornbeth BA, Lygren I, Klow NE (2008)
Transcatheter arterial embolization in the management of bleeding duodenal ulcers: A 5.5-year retrospective study of treatment and outcome
Scand. J. Gastroenterol., 43 (2), 217-222
DOI 10.1080/00365520701676443

Mahic M, Henjum K, Yaqub S, Bjornbeth BA, Torgersen KM, Tasken K, Aandahl EM (2008)
Generation of highly suppressive adaptive CD8(+)CD25(+)FOXP3(+) regulatory T cells by continuous antigen stimulation
Eur. J. Immunol., 38 (3), 640-646
DOI 10.1002/eji.200737529

Yaqub S, Henjum K, Mahic M, Jahnsen FL, Aandahl EM, Bjornbeth BA, Tasken K (2008)
Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner
Cancer Immunol. Immunother., 57 (6), 813-821
DOI 10.1007/s00262-007-0417-x

Publications 2000

Bjørnbeth BA (2000)
Bilirubinindusert cholestase
Institutt for eksperimentell medisinsk forskning, Universitetet i Oslo, Ullevål sykehus, Oslo, 66 s.
BIBSYS 000864005, ISBN 82-90246-56-0