Publications from OUS - Dept. of Microbiology, Nilsen - Genome Instability in Ageing and Disease
33 publications found
Publications 2025
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EpiMapper: A new tool for analyzing high-throughput sequencing from CUT&Tag
Comput Biol Med, 186, 109692
DOI 10.1016/j.compbiomed.2025.109692, PubMed 39832438 -
Decreased mitochondrial NAD+ in WRN deficient cells links to dysfunctional proliferation
Aging (Albany NY), null (in press)
DOI 10.18632/aging.206236, PubMed 40179319 -
Preparation and Characterization of an Engineered FGF1 Conjugated to 161Tb for Targeting of FGFRs
ACS Omega, 10 (6), 5730-5743
DOI 10.1021/acsomega.4c09179, PubMed 39989790 -
AOP-networkFinder-a versatile tool for the reconstruction and visualization of Adverse Outcome Pathway networks from AOP-Wiki
Bioinform Adv, 5 (1), vbaf007
DOI 10.1093/bioadv/vbaf007, PubMed 39968376
Publications 2024
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Loss of alkyladenine DNA glycosylase alters gene expression in the developing mouse brain and leads to reduced anxiety and improved memory
DNA Repair (Amst), 135, 103632
DOI 10.1016/j.dnarep.2024.103632, PubMed 38280242 -
Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study
Nat Commun, 15 (1), 1791
DOI 10.1038/s41467-024-46033-0, PubMed 38424056 -
Topology-guided polar ordering of collective cell migration
Sci Adv, 10 (16), eadk4825
DOI 10.1126/sciadv.adk4825, PubMed 38630812 -
Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells
Free Radic Biol Med, 213, 470-487
DOI 10.1016/j.freeradbiomed.2024.01.037, PubMed 38301978 -
Complete response of metastatic microsatellite-stable BRAF V600E colorectal cancer to first-line oxaliplatin-based chemotherapy and immune checkpoint blockade
Oncoimmunology, 13 (1), 2372886
DOI 10.1080/2162402X.2024.2372886, PubMed 38952672 -
Nicotinamide riboside first alleviates symptoms but later downregulates dopamine metabolism in proteasome inhibition mouse model of Parkinson's disease
Heliyon, 10 (14), e34355
DOI 10.1016/j.heliyon.2024.e34355, PubMed 39108921 -
Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies
J Gerontol A Biol Sci Med Sci, 79 (4)
DOI 10.1093/gerona/glae029, PubMed 38289789 -
Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients
J Clin Immunol, 44 (6), 133
DOI 10.1007/s10875-024-01726-5, PubMed 38780872
Publications 2023
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Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases
Cell Rep Med, 4 (10), 101211
DOI 10.1016/j.xcrm.2023.101211, PubMed 37797615 -
hGSuite HyperBrowser: A web-based toolkit for hierarchical metadata-informed analysis of genomic tracks
PLoS One, 18 (7), e0286330
DOI 10.1371/journal.pone.0286330, PubMed 37467208 -
TiSA: TimeSeriesAnalysis-a pipeline for the analysis of longitudinal transcriptomics data
NAR Genom Bioinform, 5 (1), lqad020
DOI 10.1093/nargab/lqad020, PubMed 36879899 -
DNA Glycosylases Define the Outcome of Endogenous Base Modifications
Int J Mol Sci, 24 (12)
DOI 10.3390/ijms241210307, PubMed 37373453 -
A homozygous POLR1A variant causes leukodystrophy and affects protein homeostasis
Brain, 146 (8), 3513-3527
DOI 10.1093/brain/awad086, PubMed 36917474 -
Long-Term Nicotinamide Riboside Use Improves Coordination and Eye Movements in Ataxia Telangiectasia
Mov Disord, 39 (2), 360-369
DOI 10.1002/mds.29645, PubMed 37899683 -
Identification of mitophagy-associated proteins profile as potential plasma biomarkers of idiopathic Parkinson's disease
CNS Neurosci Ther, 30 (4), e14532
DOI 10.1111/cns.14532, PubMed 37990436 -
The role of PGM1isoform 2 in PGM1-CDG: One step closer to genotype-phenotype correlation?
J Inherit Metab Dis, 46 (2), 159-160
DOI 10.1002/jimd.12601, PubMed 36843136 -
HoCoRT: host contamination removal tool
BMC Bioinformatics, 24 (1), 371
DOI 10.1186/s12859-023-05492-w, PubMed 37784008 -
Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players
iScience, 26 (4), 106448
DOI 10.1016/j.isci.2023.106448, PubMed 37020951 -
Targeted Central Nervous System Irradiation with Proton Microbeam Induces Mitochondrial Changes in Caenorhabditis elegans
Biology (Basel), 12 (6)
DOI 10.3390/biology12060839, PubMed 37372124 -
Missense mutation Q384K in the APOB gene affecting the large lipid transfer module of apoB reduces the secretion of apoB-100 in the liver without reducing the secretion of apoB-48 in the intestine
J Clin Lipidol, 17 (6), 800-807
DOI 10.1016/j.jacl.2023.08.009, PubMed 37718180 -
Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP
PLoS One, 18 (12), e0294764
DOI 10.1371/journal.pone.0294764, PubMed 38039300
Publications 2022
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Dynamic features of human mitochondrial DNA maintenance and transcription
Front Cell Dev Biol, 10, 984245
DOI 10.3389/fcell.2022.984245, PubMed 36158192 -
SMUG1 regulates fat homeostasis leading to a fatty liver phenotype in mice
DNA Repair (Amst), 120, 103410
DOI 10.1016/j.dnarep.2022.103410, PubMed 36244177 -
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 225
DOI 10.1186/s12967-022-03432-5, PubMed 35568909 -
Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 317
DOI 10.1186/s12967-022-03518-0, PubMed 35841045 -
A regulatory network comprising let-7 miRNA and SMUG1 is associated with good prognosis in ER+ breast tumours
Nucleic Acids Res, 50 (18), 10449-10468
DOI 10.1093/nar/gkac807, PubMed 36156150 -
C. elegans as an Animal Model to Study the Intersection of DNA Repair, Aging and Neurodegeneration
Front Aging, 3, 916118
DOI 10.3389/fragi.2022.916118, PubMed 35821838 -
Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging
Aging (Albany NY), 14 (21), 8661-8687
DOI 10.18632/aging.204375, PubMed 36367773 -
Correction: Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits
J Exp Med, 219 (8)
DOI 10.1084/jem.2021239107142022c, PubMed 35878878