Knut E. A. Lundin
- Professor, consultant; MD, PhD
Publications 2024
Selective activation of naïve B cells with unique epitope specificity shapes autoantibody formation in celiac disease
J Autoimmun, 146, 103241
DOI 10.1016/j.jaut.2024.103241, PubMed 38754235
Transcriptomic analysis of intestine following administration of a transglutaminase 2 inhibitor to prevent gluten-induced intestinal damage in celiac disease
Nat Immunol, 25 (7), 1218-1230
DOI 10.1038/s41590-024-01867-0, PubMed 38914866
Correction: COVID-19 and its effects on endothelium in HIV-positive patients in sub-saharan Africa: cardiometabolic risk, thrombosis and vascular function (ENDOCOVID STUDY)
BMC Infect Dis, 24 (1), 207
DOI 10.1186/s12879-023-08933-2, PubMed 38360639
Suboptimal adherence to a gluten-free diet in adults with both type 1 diabetes and celiac disease using urinary gluten immunogenic peptide measurement
Scand J Gastroenterol, 1-9 (in press)
DOI 10.1080/00365521.2024.2442688, PubMed 39709550
Effects of fructan and gluten on gut microbiota in individuals with self-reported non-celiac gluten/wheat sensitivity-a randomised controlled crossover trial
BMC Med, 22 (1), 358
DOI 10.1186/s12916-024-03562-1, PubMed 39227818
Biopsy Proteome Scoring to Determine Mucosal Remodeling in Celiac Disease
Gastroenterology, 167 (3), 493-504.e10
DOI 10.1053/j.gastro.2024.03.006, PubMed 38467384
Review article: Faecal biomarkers for assessing small intestinal damage in coeliac disease and environmental enteropathy
Aliment Pharmacol Ther, 60 (8), 988-1004
DOI 10.1111/apt.18234, PubMed 39233618
Generation of circulating autoreactive pre-plasma cells fueled by naive B cells in celiac disease
Cell Rep, 43 (4), 114045
DOI 10.1016/j.celrep.2024.114045, PubMed 38578826
The Prevalence and Rate of Undiagnosed Celiac Disease in an Adult General Population, the Trøndelag Health Study, Norway
Clin Gastroenterol Hepatol (in press)
DOI 10.1016/j.cgh.2024.06.027, PubMed 38987013
Gluten-Free Diet Induces Rapid Changes in Phenotype and Survival Properties of Gluten-Specific T Cells in Celiac Disease
Gastroenterology, 167 (2), 250-263
DOI 10.1053/j.gastro.2024.03.027, PubMed 38552723
Diagnosis of Seronegative and Ultrashort Celiac Disease
Gastroenterology, 167 (1), 104-115
DOI 10.1053/j.gastro.2024.01.029, PubMed 38286391
Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients
J Clin Immunol, 44 (6), 133
DOI 10.1007/s10875-024-01726-5, PubMed 38780872
Publications 2023
Expression of transglutaminase 2 in human gut epithelial cells: Implications for coeliac disease
PLoS One, 18 (6), e0287662
DOI 10.1371/journal.pone.0287662, PubMed 37368893
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
J Allergy Clin Immunol, 152 (1), 278-289.e6
DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861
Identification of gluten T cell epitopes driving celiac disease
Sci Adv, 9 (4), eade5800
DOI 10.1126/sciadv.ade5800, PubMed 36696493
Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), 10 (25), e2300401
DOI 10.1002/advs.202300401, PubMed 37424036
Guidelines for best practices in monitoring established coeliac disease in adult patients
Nat Rev Gastroenterol Hepatol, 21 (3), 198-215
DOI 10.1038/s41575-023-00872-2, PubMed 38110546
Experiences with Gluten-Free Bread: A Qualitative Study Amongst People with Coeliac Disease Participating in a Randomised Controlled Trial
Foods, 12 (23)
DOI 10.3390/foods12234338, PubMed 38231857
Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease
Nature, 624 (7992), 653-662
DOI 10.1038/s41586-023-06776-0, PubMed 37993717
Effects of a low FODMAP diet on gut microbiota in individuals with treated coeliac disease having persistent gastrointestinal symptoms - a randomised controlled trial
Br J Nutr, 130 (12), 2061-2075
DOI 10.1017/S0007114523001253, PubMed 37272479
Standardizing Randomized Controlled Trials in Celiac Disease: An International Multidisciplinary Appropriateness Study
Gastroenterology, 166 (1), 88-102
DOI 10.1053/j.gastro.2023.08.051, PubMed 37704112
[PSA screening]
Tidsskr Nor Laegeforen, 143 (12)
DOI 10.4045/tidsskr.23.0530, PubMed 37668127
Effects of faecal microbiota transplantation on the small intestinal mucosa in systemic sclerosis
Rheumatology (Oxford), 62 (8), 2918-2929
DOI 10.1093/rheumatology/kead014, PubMed 36688692
Nutritional assessment of women with celiac disease compared to the general population
Clin Nutr ESPEN, 54, 251-257
DOI 10.1016/j.clnesp.2023.01.031, PubMed 36963870
Publications 2022
Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease
Nat Commun, 13 (1), 4920
DOI 10.1038/s41467-022-32691-5, PubMed 35995787
Phenotype-Based Isolation of Antigen-Specific CD4+ T Cells in Autoimmunity: A Study of Celiac Disease
Adv Sci (Weinh), 9 (10), e2104766
DOI 10.1002/advs.202104766, PubMed 35119226
Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T-Cell-Directed Therapies
Adv Sci (Weinh), 9 (34), e2205912
DOI 10.1002/advs.202205912, PubMed 36482157
TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences
Brief Bioinform, 23 (2)
DOI 10.1093/bib/bbab566, PubMed 35062022
Immune responses to SARS-CoV-2 vaccines in celiac disease
Scand J Gastroenterol, 58 (2), 142-147
DOI 10.1080/00365521.2022.2114809, PubMed 36049123
The development and validation of a high-capacity serological assay for celiac disease
Clin Biochem, 107, 13-18
DOI 10.1016/j.clinbiochem.2022.05.010, PubMed 35660483
Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses
J Allergy Clin Immunol, 151 (3), 767-777
DOI 10.1016/j.jaci.2022.09.029, PubMed 36220400
Seronegative coeliac disease and non-coeliac enteropathies: precision medicine, precision medicine, where are you?
Gut, 71 (11), 2148-2149
DOI 10.1136/gutjnl-2022-327768, PubMed 36104222
Detection of gluten immunogenic peptides and the Celiac Disease Adherence Test to monitor gluten-free diet: a pilot study
Eur J Clin Nutr, 76 (6), 902-903
DOI 10.1038/s41430-021-01054-6, PubMed 35001079
A Low FODMAP Diet Reduces Symptoms in Treated Celiac Patients With Ongoing Symptoms-A Randomized Controlled Trial
Clin Gastroenterol Hepatol, 20 (10), 2258-2266.e3
DOI 10.1016/j.cgh.2022.01.011, PubMed 35051648
Focused B cell response to recurring gluten motif with implications for epitope spreading in celiac disease
Cell Rep, 41 (4), 111541
DOI 10.1016/j.celrep.2022.111541, PubMed 36288703
Publications 2021
Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells
Sci Rep, 11 (1), 9252
DOI 10.1038/s41598-021-86612-5, PubMed 33927210
Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T-Cell-Directed Therapies
Adv Sci (Weinh), 8 (21), e2102778
DOI 10.1002/advs.202102778, PubMed 34495570
Comprehensive Analysis of CDR3 Sequences in Gluten-Specific T-Cell Receptors Reveals a Dominant R-Motif and Several New Minor Motifs
Front Immunol, 12, 639672
DOI 10.3389/fimmu.2021.639672, PubMed 33927715
Single-cell TCR repertoire analysis reveals highly polyclonal composition of human intraepithelial CD8+ αβ T lymphocytes in untreated celiac disease
Eur J Immunol, 51 (6), 1542-1545
DOI 10.1002/eji.202048974, PubMed 33559929
A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation
Sci Immunol, 6 (62)
DOI 10.1126/sciimmunol.abg4925, PubMed 34417258
COVID-19 and its effects on endothelium in HIV-positive patients in sub-Saharan Africa: Cardiometabolic risk, thrombosis and vascular function (ENDOCOVID STUDY)
BMC Infect Dis, 21 (1), 719
DOI 10.1186/s12879-021-06426-8, PubMed 34332551
Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells
J Exp Med, 218 (2)
DOI 10.1084/jem.20200852, PubMed 33095260
Understanding celiac disease monitoring patterns and outcomes after diagnosis: A multinational, retrospective chart review study
World J Gastroenterol, 27 (20), 2603-2614
DOI 10.3748/wjg.v27.i20.2603, PubMed 34092978
Medical education in a pandemic era
Tidsskr. Nor. Laegeforen., 141 (12), 1144
[Medical education and training during a pandemic]
Tidsskr Nor Laegeforen, 141
DOI 10.4045/tidsskr.21.0581, PubMed 34505488
Nutritional quality and costs of gluten-free products: a case-control study of food products on the Norwegian marked
Food Nutr Res, 65
DOI 10.29219/fnr.v65.6121, PubMed 33841066
Frequency of Gluten-Reactive T Cells in Active Celiac Lesions Estimated by Direct Cell Cloning
Front Immunol, 12, 646163
DOI 10.3389/fimmu.2021.646163, PubMed 33796112
Circulating CD103+ γδ and CD8+ T cells are clonally shared with tissue-resident intraepithelial lymphocytes in celiac disease
Mucosal Immunol, 14 (4), 842-851
DOI 10.1038/s41385-021-00385-8, PubMed 33654213
Statement of the Prolamin Working Group on the Determination of Gluten in Fermented Foods Containing Partially Hydrolyzed Gluten
Front Nutr, 7, 626712
DOI 10.3389/fnut.2020.626712, PubMed 33511151
THE AUTHORS REPLY
N. Engl. J. Med., 385 (16)
A Trial of a Transglutaminase 2 Inhibitor in Celiac Disease. Reply
N Engl J Med, 385 (16), e57
DOI 10.1056/NEJMc2112688, PubMed 34644485
A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease
N Engl J Med, 385 (1), 35-45
DOI 10.1056/NEJMoa2032441, PubMed 34192430
Machine Learning Analysis of Naïve B-Cell Receptor Repertoires Stratifies Celiac Disease Patients and Controls
Front Immunol, 12, 627813
DOI 10.3389/fimmu.2021.627813, PubMed 33790900
Mortality and microbial diversity after allogeneic hematopoietic stem cell transplantation: secondary analysis of a randomized nutritional intervention trial
Sci Rep, 11 (1), 11593
DOI 10.1038/s41598-021-90976-z, PubMed 34078971
Erik Thorsby (1938-2021)
Immunogenetics, 73 (3), 203-205
DOI 10.1007/s00251-021-01218-5, PubMed 33956175
In memoriam: Erik Thorsby (1938-2021)
Scand. J. Immunol., 94 (1), e13055
DOI 10.1111/sji.13055
In Well-Treated Celiac Patients Low-Level Mucosal Inflammation Predicts Response to 14-day Gluten Challenge
Adv Sci (Weinh), 8 (4), 2003526
DOI 10.1002/advs.202003526, PubMed 33643806
High disease burden in treated celiac patients - a web-based survey
Scand J Gastroenterol, 56 (8), 882-888
DOI 10.1080/00365521.2021.1930146, PubMed 34057009
Differential expression profile of gluten-specific T cells identified by single-cell RNA-seq
PLoS One, 16 (10), e0258029
DOI 10.1371/journal.pone.0258029, PubMed 34618841
Publications 2020
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393
Experiences of managing a gluten-free diet on multiple levels of society: a qualitative study
BMC Nutr, 6 (1), 65
DOI 10.1186/s40795-020-00390-3, PubMed 33292694
Efficacy and Safety of CT-P13 in Inflammatory Bowel Disease after Switching from Originator Infliximab: Exploratory Analyses from the NOR-SWITCH Main and Extension Trials
BioDrugs, 34 (5), 681-694
DOI 10.1007/s40259-020-00438-7, PubMed 32965617
Recent Progress and Recommendations on Celiac Disease From the Working Group on Prolamin Analysis and Toxicity
Front Nutr, 7, 29
DOI 10.3389/fnut.2020.00029, PubMed 32258047
A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease
Proc Natl Acad Sci U S A, 117 (6), 3063-3073
DOI 10.1073/pnas.1914308117, PubMed 31974305
T cell receptor repertoire as a potential diagnostic marker for celiac disease
Clin Immunol, 222, 108621
DOI 10.1016/j.clim.2020.108621, PubMed 33197618
Publications 2019
European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders
United European Gastroenterol J, 7 (5), 583-613
DOI 10.1177/2050640619844125, PubMed 31210940
Determination of lower cut-off levels of adalimumab associated with biochemical remission in Crohn's disease
JGH Open, 4 (3), 410-416
DOI 10.1002/jgh3.12266, PubMed 32514446
Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions
Nat Med, 25 (5), 734-737
DOI 10.1038/s41591-019-0403-9, PubMed 30911136
On the immune response to barley in celiac disease: Biased and public T-cell receptor usage to a barley unique and immunodominant gluten epitope
Eur J Immunol, 50 (2), 256-269
DOI 10.1002/eji.201948253, PubMed 31628754
Single-cell TCR sequencing of gut intraepithelial γδ T cells reveals a vast and diverse repertoire in celiac disease
Mucosal Immunol, 13 (2), 313-321
DOI 10.1038/s41385-019-0222-9, PubMed 31728027
Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping
Nat Commun, 10 (1), 628
DOI 10.1038/s41467-019-08489-3, PubMed 30733445
Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease
Sci Adv, 5 (8), eaaw7756
DOI 10.1126/sciadv.aaw7756, PubMed 31457091
Long-term efficacy and safety of biosimilar infliximab (CT-P13) after switching from originator infliximab: open-label extension of the NOR-SWITCH trial
J Intern Med, 285 (6), 653-669
DOI 10.1111/joim.12880, PubMed 30762274
No major reduction in bone mineral density after long-term treatment of patients with Celiac Disease
Eur J Intern Med, 68, 23-29
DOI 10.1016/j.ejim.2019.07.024, PubMed 31401019
Efficient T cell-B cell collaboration guides autoantibody epitope bias and onset of celiac disease
Proc Natl Acad Sci U S A, 116 (30), 15134-15139
DOI 10.1073/pnas.1901561116, PubMed 31285344
Enterovirus as trigger of coeliac disease: nested case-control study within prospective birth cohort
BMJ, 364, l231
DOI 10.1136/bmj.l231, PubMed 30760441
Coeliac disease
Nat Rev Dis Primers, 5 (1), 3
DOI 10.1038/s41572-018-0054-z, PubMed 30631077
Dietary and symptom assessment in adults with self-reported non-coeliac gluten sensitivity
Clin Nutr ESPEN, 31, 88-94
DOI 10.1016/j.clnesp.2019.02.012, PubMed 31060839
Transcriptional profiling of human intestinal plasma cells reveals effector functions beyond antibody production
United European Gastroenterol J, 7 (10), 1399-1407
DOI 10.1177/2050640619862461, PubMed 31839965
A system for students' evaluation of lectures in the medical programme in Oslo
Tidsskr. Nor. Laegeforen., 139 (11), 1056-1060
A system for students' evaluation of lectures in the medical programme in Oslo
Tidsskr Nor Laegeforen, 139 (11)
DOI 10.4045/tidsskr.19.0027, PubMed 31429231
Cytokine release after gluten ingestion differentiates coeliac disease from self-reported gluten sensitivity
United European Gastroenterol J, 8 (1), 108-118
DOI 10.1177/2050640619874173, PubMed 32213060
CD38 expression on gluten-specific T cells is a robust marker of gluten re-exposure in coeliac disease
United European Gastroenterol J, 7 (10), 1337-1344
DOI 10.1177/2050640619874183, PubMed 31839959
Publications 2018
Subtherapeutic concentrations of infliximab and adalimumab are associated with increased disease activity in Crohn's disease
Therap Adv Gastroenterol, 11, 1756284818759930
DOI 10.1177/1756284818759930, PubMed 29623105
Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes
J Biol Chem, 294 (3), 941-952
DOI 10.1074/jbc.RA118.005736, PubMed 30455354
Is Non-Celiac Rice-Starch Sensitivity as Common in Children as Non-Celiac Gluten Sensitivity?
Am J Gastroenterol, 113 (8), 1254
DOI 10.1038/s41395-018-0079-7, PubMed 29880973
Positive IgA against transglutaminase 2 in patients with distal radius and ankle fractures compared to community-based controls
Scand J Gastroenterol, 53 (10-11), 1212-1216
DOI 10.1080/00365521.2018.1509122, PubMed 30265163
Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease
Gastroenterology, 156 (5), 1428-1439.e10
DOI 10.1053/j.gastro.2018.12.013, PubMed 30593798
Fatigue as an Extra-Intestinal Manifestation of Celiac Disease: A Systematic Review
Nutrients, 10 (11)
DOI 10.3390/nu10111652, PubMed 30400298
Outcome measures in coeliac disease trials: the Tampere recommendations
Gut, 67 (8), 1410-1424
DOI 10.1136/gutjnl-2017-314853, PubMed 29440464
Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease
J Clin Invest, 128 (6), 2642-2650
DOI 10.1172/JCI98819, PubMed 29757191
Reply
Gastroenterology, 155 (1), 228
DOI 10.1053/j.gastro.2018.06.032, PubMed 29894682
Effects of individualized nutrition after allogeneic hematopoietic stem cell transplantation following myeloablative conditioning; a randomized controlled trial
Clin Nutr ESPEN, 28, 59-66
DOI 10.1016/j.clnesp.2018.08.002, PubMed 30390894
Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry
Am J Pathol, 188 (7), 1563-1579
DOI 10.1016/j.ajpath.2018.03.017, PubMed 29684362
Publications 2017
Linking Spatial Structure and Community-Level Biotic Interactions through Cooccurrence and Time Series Modeling of the Human Intestinal Microbiota
mSystems, 2 (5)
DOI 10.1128/mSystems.00086-17, PubMed 28904999
Electives in the medical degree programme
Tidsskr Nor Laegeforen, 137 (20)
DOI 10.4045/tidsskr.17.0549, PubMed 29094564
Elective courses in medicine studies
Tidsskr. Nor. Laegeforen., 137 (20), 1592-1594
Non-coeliac gluten sensitivity
J Gastroenterol Hepatol, 32 Suppl 1, 86-89
DOI 10.1111/jgh.13705, PubMed 28244667
A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions
JCI Insight, 2 (17)
DOI 10.1172/jci.insight.95193, PubMed 28878121
Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins
Cell Rep, 20 (10), 2357-2367
DOI 10.1016/j.celrep.2017.08.036, PubMed 28877470
Efficacy of infliximab biosimilars in patients with Crohn's disease - Authors' reply
Lancet, 390 (10111), 2436
DOI 10.1016/S0140-6736(17)32463-7, PubMed 29208304
Switching from originator infliximab to biosimilar CT-P13 compared with maintained treatment with originator infliximab (NOR-SWITCH): a 52-week, randomised, double-blind, non-inferiority trial
Lancet, 389 (10086), 2304-2316
DOI 10.1016/S0140-6736(17)30068-5, PubMed 28502609
CVID and Celiac Disease
Am J Gastroenterol, 112 (2), 393
DOI 10.1038/ajg.2016.551, PubMed 28154406
Early growth in children with coeliac disease: a cohort study
Arch Dis Child, 102 (11), 1037-1043
DOI 10.1136/archdischild-2016-312304, PubMed 28611068
High-Throughput Single-Cell Analysis of B Cell Receptor Usage among Autoantigen-Specific Plasma Cells in Celiac Disease
J Immunol, 199 (2), 782-791
DOI 10.4049/jimmunol.1700169, PubMed 28600290
HLA-DQ-Gluten Tetramer Blood Test Accurately Identifies Patients With and Without Celiac Disease in Absence of Gluten Consumption
Gastroenterology, 154 (4), 886-896.e6
DOI 10.1053/j.gastro.2017.11.006, PubMed 29146521
HLA-DQ:gluten tetramer test in blood gives better detection of coeliac patients than biopsy after 14-day gluten challenge
Gut, 67 (9), 1606-1613
DOI 10.1136/gutjnl-2017-314461, PubMed 28779027
Fructan, Rather Than Gluten, Induces Symptoms in Patients With Self-Reported Non-Celiac Gluten Sensitivity
Gastroenterology, 154 (3), 529-539.e2
DOI 10.1053/j.gastro.2017.10.040, PubMed 29102613
Stereotyped antibody responses target posttranslationally modified gluten in celiac disease
JCI Insight, 2 (17)
DOI 10.1172/jci.insight.93961, PubMed 28878138
Publications 2016
Healthy HLA-DQ2.5+ Subjects Lack Regulatory and Memory T Cells Specific for Immunodominant Gluten Epitopes of Celiac Disease
J Immunol, 196 (6), 2819-26
DOI 10.4049/jimmunol.1501152, PubMed 26895834
Targeting Integrin α4β7 in Steroid-Refractory Intestinal Graft-versus-Host Disease
Biol Blood Marrow Transplant, 23 (1), 172-175
DOI 10.1016/j.bbmt.2016.10.009, PubMed 27777142
Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease
J Hepatol, 66 (1), 116-122
DOI 10.1016/j.jhep.2016.09.002, PubMed 27647428
Long-term mucosal recovery and healing in celiac disease is the rule - not the exception
Scand J Gastroenterol, 51 (12), 1439-1446
DOI 10.1080/00365521.2016.1218540, PubMed 27534885
A Cross-Sectional Study of the Prevalence of Gastrointestinal Symptoms and Pathology in Patients With Common Variable Immunodeficiency
Am J Gastroenterol, 111 (10), 1467-1475
DOI 10.1038/ajg.2016.329, PubMed 27527747
Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
Mucosal Immunol, 9 (6), 1455-1465
DOI 10.1038/mi.2016.18, PubMed 26982597
Transition from childhood to adulthood in coeliac disease: the Prague consensus report
Gut, 65 (8), 1242-51
DOI 10.1136/gutjnl-2016-311574, PubMed 27196596
Wheat challenge in self-reported gluten sensitivity: a comparison of scoring methods
Scand J Gastroenterol, 52 (2), 185-192
DOI 10.1080/00365521.2016.1244705, PubMed 27797273
Publications 2015
Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma
Hepatology, 61 (5), 1651-9
DOI 10.1002/hep.27707, PubMed 25644509
Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts' Criteria
Nutrients, 7 (6), 4966-77
DOI 10.3390/nu7064966, PubMed 26096570
Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease
Mucosal Immunol, 9 (1), 254-64
DOI 10.1038/mi.2015.57, PubMed 26153762
Coeliac disease - from genetic and immunological studies to clinical applications
Scand J Gastroenterol, 50 (6), 708-17
DOI 10.3109/00365521.2015.1030766, PubMed 25846940
Coeliac disease and autoimmune disease-genetic overlap and screening
Nat Rev Gastroenterol Hepatol, 12 (9), 507-15
DOI 10.1038/nrgastro.2015.136, PubMed 26303674
Analysis of celiac disease autoreactive gut plasma cells and their corresponding memory compartment in peripheral blood using high-throughput sequencing
J Immunol, 194 (12), 5703-12
DOI 10.4049/jimmunol.1402611, PubMed 25972486
Small bowel, celiac disease and adaptive immunity
Dig Dis, 33 (2), 115-121
DOI 10.1159/000369512, PubMed 25925911
Serologic assay for diagnosis of celiac disease based on a patient-derived monoclonal antigliadin antibody
Gastroenterology, 149 (6), 1530-1540.e3
DOI 10.1053/j.gastro.2015.07.008, PubMed 26208894
Non-celiac gluten sensitivity: a work-in-progress entity in the spectrum of wheat-related disorders
Best Pract Res Clin Gastroenterol, 29 (3), 477-91
DOI 10.1016/j.bpg.2015.04.006, PubMed 26060112
Publications 2014
Tetramer-visualized gluten-specific CD4+ T cells in blood as a potential diagnostic marker for coeliac disease without oral gluten challenge
United European Gastroenterol J, 2 (4), 268-78
DOI 10.1177/2050640614540154, PubMed 25083284
[The grading system--balancing various interests]
Tidsskr Nor Laegeforen, 134 (1), 14-5
DOI 10.4045/tidsskr.13.1338, PubMed 24429749
[J. Frich and colleagues reply]
Tidsskr Nor Laegeforen, 134 (5), 496; discussion 497
DOI 10.4045/tidsskr.14.0202, PubMed 24621892
Celiac disease and risk of fracture in adults--a review
Osteoporos Int, 25 (6), 1667-76
DOI 10.1007/s00198-014-2683-8, PubMed 24691647
Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology
Gut, 63 (8), 1210-28
DOI 10.1136/gutjnl-2013-306578, PubMed 24917550
Non-celiac gluten sensitivity - why worry?
BMC Med, 12, 86
DOI 10.1186/1741-7015-12-86, PubMed 24885490
Advances in coeliac disease
Curr Opin Gastroenterol, 30 (2), 154-62
DOI 10.1097/MOG.0000000000000041, PubMed 24457347
Issues associated with the emergence of coeliac disease in the Asia–Pacific region: a working party report of the World Gastroenterology Organization and the Asian Pacific Association of Gastroenterology
J Gastroenterol Hepatol, 29 (4), 666-77
DOI 10.1111/jgh.12514, PubMed 24783246
Biosimilar medicines in inflammatory bowel disease
Tidsskr Nor Laegeforen, 134 (8), 819-20
DOI 10.4045/tidsskr.14.0192, PubMed 24780979
Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells
Nat Commun, 5, 4041
DOI 10.1038/ncomms5041, PubMed 24909383
Publications 2013
Direct cloning and tetramer staining to measure the frequency of intestinal gluten-reactive T cells in celiac disease
Eur J Immunol, 43 (10), 2605-12
DOI 10.1002/eji.201343382, PubMed 23775608
Mucosal cytokine response after short-term gluten challenge in celiac disease and non-celiac gluten sensitivity
Am J Gastroenterol, 108 (5), 842-50
DOI 10.1038/ajg.2013.91, PubMed 23588237
Transglutaminase 2-specific autoantibodies in celiac disease target clustered, N-terminal epitopes not displayed on the surface of cells
J Immunol, 190 (12), 5981-91
DOI 10.4049/jimmunol.1300183, PubMed 23690478
Increased frequency of intestinal CD4+ T cells reactive with mycobacteria in patients with Crohn's disease
Scand J Gastroenterol, 48 (11), 1278-85
DOI 10.3109/00365521.2013.837952, PubMed 24131402
Biased usage and preferred pairing of α- and β-chains of TCRs specific for an immunodominant gluten epitope in coeliac disease
Int Immunol, 26 (1), 13-9
DOI 10.1093/intimm/dxt037, PubMed 24038601
Association between maternal iron supplementation during pregnancy and risk of celiac disease in children
Clin Gastroenterol Hepatol, 12 (4), 624-31.e1-2
DOI 10.1016/j.cgh.2013.09.061, PubMed 24112997
Publications 2012
Rapid accumulation of CD14+CD11c+ dendritic cells in gut mucosa of celiac disease after in vivo gluten challenge
PLoS One, 7 (3), e33556
DOI 10.1371/journal.pone.0033556, PubMed 22438948
Evidence that HLA-DQ9 confers risk to celiac disease by presence of DQ9-restricted gluten-specific T cells
Hum Immunol, 73 (4), 376-81
DOI 10.1016/j.humimm.2012.01.016, PubMed 22342873
Absence of somatization in non-coeliac gluten sensitivity
Scand J Gastroenterol, 47 (7), 770-7
DOI 10.3109/00365521.2012.679685, PubMed 22519894
Video capsule endoscopy in celiac disease: current clinical practice
J Dig Dis, 13 (2), 94-9
DOI 10.1111/j.1751-2980.2011.00561.x, PubMed 22257477
High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
Nat Med, 18 (3), 441-5
DOI 10.1038/nm.2656, PubMed 22366952
The Oslo definitions for coeliac disease and related terms
Gut, 62 (1), 43-52
DOI 10.1136/gutjnl-2011-301346, PubMed 22345659
Non-celiac gluten sensitivity
Gastrointest Endosc Clin N Am, 22 (4), 723-34
DOI 10.1016/j.giec.2012.07.006, PubMed 23083989
Publications 2011
T-cell response to gluten in patients with HLA-DQ2.2 reveals requirement of peptide-MHC stability in celiac disease
Gastroenterology, 142 (3), 552-61
DOI 10.1053/j.gastro.2011.11.021, PubMed 22108197
INSPIRE study: does stress management improve the course of inflammatory bowel disease and disease-specific quality of life in distressed patients with ulcerative colitis or Crohn's disease? A randomized controlled trial
Inflamm Bowel Dis, 17 (9), 1863-73
DOI 10.1002/ibd.21575, PubMed 21287660
Assessing possible celiac disease by an HLA-DQ2-gliadin Tetramer Test
Am J Gastroenterol, 106 (7), 1318-24
DOI 10.1038/ajg.2011.23, PubMed 21364548
CD62L(neg)CD38⁺ expression on circulating CD4⁺ T cells identifies mucosally differentiated cells in protein fed mice and in human celiac disease patients and controls
Am J Gastroenterol, 106 (6), 1147-59
DOI 10.1038/ajg.2011.24, PubMed 21386831
Endoscopic stent treatment of a duodenal ulcer perforation
Endoscopy, 43 Suppl 2 UCTN, E60
DOI 10.1055/s-0030-1256079, PubMed 21287454
Inflammatory bowel disease in patients with primary sclerosing cholangitis: clinical characterization in liver transplanted and nontransplanted patients
Inflamm Bowel Dis, 18 (3), 536-45
DOI 10.1002/ibd.21699, PubMed 21456044
Long-lived plasma cells from human small intestine biopsies secrete immunoglobulins for many weeks in vitro
J Immunol, 187 (6), 2867-74
DOI 10.4049/jimmunol.1003181, PubMed 21841131
Posttranslational modification of gluten shapes TCR usage in celiac disease
J Immunol, 187 (6), 3064-71
DOI 10.4049/jimmunol.1101526, PubMed 21849672
Publications 2010
HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22
Mucosal Immunol, 3 (6), 594-601
DOI 10.1038/mi.2010.36, PubMed 20571486
Rapid generation of rotavirus-specific human monoclonal antibodies from small-intestinal mucosa
J Immunol, 185 (9), 5377-83
DOI 10.4049/jimmunol.1001587, PubMed 20935207
Intestinal malabsorption of D-xylose: comparison of test modalities in patients with celiac disease
Scand J Gastroenterol, 45 (11), 1289-94
DOI 10.3109/00365521.2010.503969, PubMed 20626306
Publications 2009
Isolation of Mycobacterium avium subspecies paratuberculosis reactive CD4 T cells from intestinal biopsies of Crohn's disease patients
PLoS One, 4 (5), e5641
DOI 10.1371/journal.pone.0005641, PubMed 19479064
Publications 2008
The INSPIRE study: are different personality traits related to disease-specific quality of life (IBDQ) in distressed patients with ulcerative colitis and Crohn's disease?
Inflamm Bowel Dis, 14 (5), 680-6
DOI 10.1002/ibd.20367, PubMed 18509900
The INSPIRE study: do personality traits predict general quality of life (Short form-36) in distressed patients with ulcerative colitis and Crohn's disease?
Scand J Gastroenterol, 43 (12), 1505-13
DOI 10.1080/00365520802321196, PubMed 18777439
[Cancer risk in coeliac disease]
Tidsskr Nor Laegeforen, 128 (20), 2312-5
PubMed 19096486
No induction of anti-avenin IgA by oats in adult, diet-treated coeliac disease
Scand J Gastroenterol, 43 (2), 161-5
DOI 10.1080/00365520701832822, PubMed 18224563
Publications 2007
Reduced chemokine receptor 9 on intraepithelial lymphocytes in celiac disease suggests persistent epithelial activation
Gastroenterology, 132 (7), 2371-82
DOI 10.1053/j.gastro.2007.04.023, PubMed 17570212
Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients
Proc Natl Acad Sci U S A, 104 (8), 2831-6
DOI 10.1073/pnas.0608610104, PubMed 17307878
Publications 2006
[New Swedish specialty structure]
Tidsskr Nor Laegeforen, 126 (12), 1594
PubMed 16770367
[Dosaging of proton pumps inhibitors]
Tidsskr Nor Laegeforen, 126 (22), 2985; author reply 2985
PubMed 17117203
A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells
Gastroenterology, 131 (2), 428-38
DOI 10.1053/j.gastro.2006.06.002, PubMed 16890596
HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease
J Clin Invest, 116 (8), 2226-36
DOI 10.1172/JCI27620, PubMed 16878175
Publications 2005
Gluten-free diet--what is toxic?
Best Pract Res Clin Gastroenterol, 19 (3), 359-71
DOI 10.1016/j.bpg.2005.01.003, PubMed 15925842
Commentary: transient coeliac disease back on stage again?
Scand J Gastroenterol, 40 (10), 1137-9
DOI 10.1080/00365520500206608, PubMed 16165700
Mapping of gluten T-cell epitopes in the bread wheat ancestors: implications for celiac disease
Gastroenterology, 128 (2), 393-401
DOI 10.1053/j.gastro.2004.11.003, PubMed 15685550
Effect of elemental diet on mucosal immunopathology and clinical symptoms in type 1 refractory celiac disease
Clin Gastroenterol Hepatol, 3 (9), 875-85
DOI 10.1016/s1542-3565(05)00295-8, PubMed 16234025
Publications 2004
The molecular basis for oat intolerance in patients with celiac disease
PLoS Med, 1 (1), e1
DOI 10.1371/journal.pmed.0010001, PubMed 15526039
[Cardiology as an engine for internal medicine]
Tidsskr Nor Laegeforen, 124 (8), 1139
PubMed 15114398
Publications 2003
[Coeliac disease--new clinical findings and diagnostic tools]
Tidsskr Nor Laegeforen, 123 (22), 3226-9
PubMed 14714016
[Dietary treatment of coeliac disease and dermatitis herpetiformis]
Tidsskr Nor Laegeforen, 123 (22), 3237-40
PubMed 14714019
Intestinal T-cell responses to high-molecular-weight glutenins in celiac disease
Gastroenterology, 125 (2), 337-44
DOI 10.1016/s0016-5085(03)00890-4, PubMed 12891534
[Disease mechanisms in coeliac disease]
Tidsskr Nor Laegeforen, 123 (22), 3230-3
PubMed 14714017
Publications 2002
Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues
Gastroenterology, 123 (3), 803-9
DOI 10.1053/gast.2002.35381, PubMed 12198706
Publications 1990
T cell recognition of HLA-DQ molecules
Institute of Transplantation Immunology, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 900878436, ISBN 82-90187-66-1